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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2160669
log Bayes Factor = 14.6357
Chromosome 11   position 116,647,607  (GRCh37) Explore rs2160669 on Ensembl!
Variant rs2160669 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.006 0.994
E78.5 Hyperlipidaemia, unspecified
0.000 0.012 0.988
E78.2 Mixed hyperlipidaemia
0.000 0.073 0.927
I10 Essential (primary) hypertension
0.000 0.191 0.809
E78.1 Pure hyperglyceridaemia
0.000 0.217 0.783
E78.4 Other hyperlipidaemia
0.000 0.261 0.739
E78.8 Other disorders of lipoprotein metabolism
0.000 0.261 0.739
E78.3 Hyperchylomicronaemia
0.000 0.297 0.703
E78.6 Lipoprotein deficiency
0.000 0.329 0.670
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.377 0.623
I10-I15 Hypertensive diseases
0.000 0.734 0.266
I11 Hypertensive heart disease
0.000 0.791 0.209
I13 Hypertensive heart and renal disease
0.000 0.800 0.200
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.823 0.177
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.847 0.153
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.851 0.149
I15 Secondary hypertension
0.000 0.856 0.144
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.856 0.144
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.862 0.137
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.866 0.134
I12 Hypertensive renal disease
0.000 0.881 0.119
I15.0 Renovascular hypertension
0.000 0.893 0.107
I15.2 Hypertension secondary to endocrine disorders
0.000 0.897 0.102
I15.8 Other secondary hypertension
0.000 0.897 0.102
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.905 0.095
I15.9 Seconday hypertension, unspecified
0.001 0.907 0.092
I71 Aortic aneurysm and dissection
0.000 0.917 0.083
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.919 0.081
Chapter IX Diseases of the circulatory system
0.000 0.920 0.080
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.920 0.080
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.921 0.079
I12.9 Hypertensive renal disease without renal failure
0.000 0.925 0.075
I70 Atherosclerosis
0.000 0.927 0.073
I15.1 Hypertension secondary to other renal disorders
0.001 0.929 0.070
I74 Arterial embolism and thrombosis
0.000 0.931 0.069
I60-I69 Cerebrovascular diseases
0.000 0.931 0.069
I34.0 Mitral (valve) insufficiency
0.000 0.937 0.063
I34 Nonrheumatic mitral valve disorders
0.000 0.938 0.062
I72 Other aneurysm
0.000 0.939 0.061
I70.0 Atherosclerosis of aorta
0.000 0.939 0.061
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.940 0.060
I30-I52 Other forms of heart disease
0.000 0.940 0.060
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.940 0.060
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.940 0.059
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.940 0.059
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.941 0.059
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.941 0.059
I45.1 Other and unspecified right bundle-branch block
0.000 0.942 0.058
I70.8 Atherosclerosis of other arteries
0.000 0.942 0.058
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.943 0.057
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.943 0.057
I45 Other conduction disorders
0.000 0.943 0.057
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.944 0.056
I00-I02 Acute rheumatic fever
0.000 0.944 0.056
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.945 0.055
I35 Nonrheumatic aortic valve disorders
0.000 0.946 0.054
I71.0 Dissection of aorta [any part]
0.000 0.946 0.054
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.946 0.054
I70.1 Atherosclerosis of renal artery
0.000 0.946 0.054
I70.9 Generalised and unspecified atherosclerosis
0.000 0.947 0.053
I42 Cardiomyopathy
0.000 0.947 0.053
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.948 0.052
I74.8 Embolism and thrombosis of other arteries
0.000 0.948 0.052
I35.0 Aortic (valve) stenosis
0.000 0.949 0.051
I74.5 Embolism and thrombosis of iliac artery
0.000 0.949 0.051
I05-I09 Chronic rheumatic heart diseases
0.000 0.950 0.050
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.950 0.050
I77 Other disorders of arteries and arterioles
0.000 0.950 0.050
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.951 0.049
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.951 0.049
I67 Other cerebrovascular diseases
0.000 0.951 0.049
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.951 0.049
I36 Nonrheumatic tricuspid valve disorders
0.000 0.951 0.048
I72.8 Aneurysm of other specified arteries
0.000 0.952 0.048
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.952 0.048
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.952 0.048
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.953 0.047
I37 Pulmonary valve disorders
0.000 0.953 0.046
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.954 0.046
I72.1 Aneurysm of artery of upper extremity
0.000 0.954 0.046
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.954 0.046
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.954 0.046
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.954 0.045
I34.1 Mitral (valve) prolapse
0.000 0.954 0.045
I77.1 Stricture of artery
0.000 0.955 0.045
I72.3 Aneurysm of iliac artery
0.000 0.955 0.045
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.955 0.045
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.955 0.045
I72.0 Aneurysm of carotid artery
0.000 0.955 0.045
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.956 0.044
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.956 0.044
I45.3 Trifascicular block
0.000 0.956 0.044
I42.9 Cardiomyopathy, unspecified
0.000 0.956 0.044
I67.8 Other specified cerebrovascular diseases
0.000 0.956 0.044
I52 Other heart disorders in diseases classified elsewhere
0.000 0.957 0.043
I48 Atrial fibrillation and flutter
0.000 0.957 0.043
I41 Myocarditis in diseases classified elsewhere
0.000 0.957 0.043
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.957 0.043
I32 Pericarditis in diseases classified elsewhere
0.000 0.957 0.043
I78 Diseases of capillaries
0.000 0.957 0.043
I72.9 Aneurysm of unspecified site
0.000 0.957 0.043
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.957 0.043
I72.4 Aneurysm of artery of lower extremity
0.000 0.957 0.043
I42.6 Alcoholic cardiomyopathy
0.000 0.957 0.043
I79.1 Aortitis in diseases classified elsewhere
0.000 0.957 0.042
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.957 0.042
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.958 0.042
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.958 0.042
I31 Other diseases of pericardium
0.000 0.958 0.042
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.958 0.041
I30 Acute pericarditis
0.000 0.958 0.042
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.959 0.041
I42.2 Other hypertrophic cardiomyopathy
0.000 0.959 0.041
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.959 0.041
I42.4 Endocardial fibroelastosis
0.000 0.959 0.040
I45.0 Right fascicular block
0.000 0.960 0.040
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.960 0.040
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.960 0.040
I12.0 Hypertensive renal disease with renal failure
0.000 0.960 0.040
I02 Rheumatic chorea
0.000 0.960 0.040
I01 Rheumatic fever with heart involvement
0.000 0.960 0.040
I38 Endocarditis, valve unspecified
0.000 0.960 0.040
I42.8 Other cardiomyopathies
0.000 0.960 0.040
I45.4 Nonspecific intraventricular block
0.000 0.960 0.040
I35.9 Aortic valve disorder, unspecified
0.000 0.960 0.040
I45.8 Other specified conduction disorders
0.000 0.960 0.040
I45.2 Bifascicular block
0.000 0.960 0.039
I69 Sequelae of cerebrovascular disease
0.000 0.961 0.039
I42.5 Other restrictive cardiomyopathy
0.000 0.961 0.039
I40 Acute myocarditis
0.000 0.961 0.039
I05 Rheumatic mitral valve diseases
0.000 0.961 0.039
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.961 0.039
I72.2 Aneurysm of renal artery
0.000 0.961 0.038
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.961 0.038
I46 Cardiac arrest
0.000 0.962 0.038
I62 Other nontraumatic intracranial haemorrhage
0.000 0.962 0.038
I99 Other and unspecified disorders of circulatory system
0.000 0.962 0.038
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.962 0.038
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.962 0.038
I00 Rheumatic fever without mention of heart involvement
0.000 0.962 0.038
I37.1 Pulmonary valve insufficiency
0.000 0.963 0.037
I45.5 Other specified heart block
0.000 0.963 0.037
I07 Rheumatic tricuspid valve diseases
0.000 0.963 0.037
I42.0 Dilated cardiomyopathy
0.000 0.963 0.037
I33 Acute and subacute endocarditis
0.000 0.963 0.037
I31.9 Disease of pericardium, unspecified
0.000 0.963 0.037
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.964 0.036
I77.5 Necrosis of artery
0.000 0.964 0.036
I77.4 Coeliac artery compression syndrome
0.000 0.964 0.036
I09 Other rheumatic heart diseases
0.000 0.964 0.036
I67.9 Cerebrovascular disease, unspecified
0.000 0.964 0.036
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.964 0.036
I77.3 Arterial fibromuscular dysplasia
0.000 0.964 0.035
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.965 0.035
I67.4 Hypertensive encephalopathy
0.000 0.965 0.035
I77.8 Other specified disorders of arteries and arterioles
0.000 0.965 0.035
I67.5 Moyamoya disease
0.000 0.965 0.035
I67.3 Progressive vascular leukoencephalopathy
0.000 0.965 0.035
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.965 0.035
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.965 0.035
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.965 0.035
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.965 0.035
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.965 0.035
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.965 0.035
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.965 0.035
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.965 0.035
I05.0 Mitral stenosis
0.000 0.965 0.035
I77.0 Arteriovenous fistula, acquired
0.000 0.965 0.034
I35.8 Other aortic valve disorders
0.000 0.966 0.034
M16.1 Other primary coxarthrosis
0.034 0.966 0.000
I68.0 Cerebral amyloid angiopathy
0.000 0.966 0.034
I78.8 Other diseases of capillaries
0.000 0.966 0.034
I37.9 Pulmonary valve disorder, unspecified
0.000 0.966 0.033
I37.8 Other pulmonary valve disorders
0.000 0.966 0.033
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.966 0.033
I63 Cerebral infarction
0.000 0.967 0.033
I06 Rheumatic aortic valve diseases
0.000 0.967 0.033
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.967 0.032
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.967 0.032
I37.0 Pulmonary valve stenosis
0.000 0.967 0.032
I45.9 Conduction disorder, unspecified
0.000 0.967 0.032
I77.2 Rupture of artery
0.000 0.968 0.032
I61 Intracerebral haemorrhage
0.000 0.968 0.032
I30.1 Infective pericarditis
0.000 0.968 0.032
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.968 0.032
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.969 0.031
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.969 0.031
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.969 0.031
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.969 0.031
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.969 0.031
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.969 0.031
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.969 0.031
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.969 0.031
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.969 0.031
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.969 0.031
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.969 0.031
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.969 0.031
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.969 0.031
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.969 0.031
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.969 0.031
I48.4 Atypical atrial flutter
0.000 0.969 0.031
I48.3 Typical atrial flutter
0.000 0.969 0.031
I48.2 Chronic atrial fibrillation
0.000 0.969 0.031
I48.1 Persistent atrial fibrillation
0.000 0.969 0.031
I48.0 Paroxysmal atrial fibrillation
0.000 0.969 0.031
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.969 0.031
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.969 0.031
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.969 0.031
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.969 0.031
I45.6 Preexcitation syndrome
0.000 0.969 0.031
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.969 0.031
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.969 0.031
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.969 0.031
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.969 0.030
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.969 0.030
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.970 0.030
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.970 0.030
I31.8 Other specified diseases of pericardium
0.000 0.970 0.030
I31.2 Haemopericardium, not elsewhere classified
0.000 0.970 0.030
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.970 0.030
I31.1 Chronic constrictive pericarditis
0.000 0.970 0.030
I30.8 Other forms of acute pericarditis
0.000 0.970 0.030
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.970 0.030
I46.1 Sudden cardiac death, so described
0.000 0.970 0.030
I78.9 Disease of capillaries, unspecified
0.000 0.970 0.030
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.970 0.030
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.970 0.030
I69.3 Sequelae of cerebral infarction
0.000 0.971 0.029
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.971 0.029
I01.8 Other acute rheumatic heart disease
0.000 0.971 0.029
I01.2 Acute rheumatic myocarditis
0.000 0.971 0.029
I01.1 Acute rheumatic endocarditis
0.000 0.971 0.029
I01.0 Acute rheumatic pericarditis
0.000 0.971 0.029
I02.9 Rheumatic chorea without heart involvement
0.000 0.971 0.029
I02.0 Rheumatic chorea with heart involvement
0.000 0.971 0.029
I31.0 Chronic adhesive pericarditis
0.000 0.971 0.029
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.971 0.029
I73 Other peripheral vascular diseases
0.000 0.971 0.029
I05.2 Mitral stenosis with insufficiency
0.000 0.971 0.028
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.972 0.028
I40.8 Other acute myocarditis
0.000 0.972 0.028
I40.1 Isolated myocarditis
0.000 0.972 0.028
I05.8 Other mitral valve diseases
0.000 0.972 0.028
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.972 0.028
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.972 0.028
I05.1 Rheumatic mitral insufficiency
0.000 0.972 0.028
I62.1 Nontraumatic extradural haemorrhage
0.000 0.972 0.028
I07.1 Tricuspid insufficiency
0.000 0.972 0.028
I67.1 Cerebral aneurysm, nonruptured
0.000 0.972 0.028
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.973 0.027
I08 Multiple valve diseases
0.000 0.973 0.027
I07.9 Tricuspid valve disease, unspecified
0.000 0.973 0.027
I07.8 Other tricuspid valve diseases
0.000 0.973 0.027
I07.2 Tricuspid stenosis with insufficiency
0.000 0.973 0.027
I07.0 Tricuspid stenosis
0.000 0.973 0.027
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.973 0.027
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.973 0.027
I40.0 Infective myocarditis
0.000 0.974 0.026
I40.9 Acute myocarditis, unspecified
0.000 0.974 0.026
I09.8 Other specified rheumatic heart diseases
0.000 0.974 0.026
I09.2 Chronic rheumatic pericarditis
0.000 0.974 0.026
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.974 0.026
I09.0 Rheumatic myocarditis
0.000 0.974 0.026
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.974 0.026
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.974 0.026
I30.9 Acute pericarditis, unspecified
0.000 0.974 0.026
I09.9 Rheumatic heart disease, unspecified
0.000 0.974 0.025
I67.2 Cerebral atherosclerosis
0.000 0.974 0.025
I61.8 Other intracerebral haemorrhage
0.000 0.974 0.025
I35.1 Aortic (valve) insufficiency
0.000 0.974 0.025
I65.1 Occlusion and stenosis of basilar artery
0.000 0.974 0.025
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.975 0.025
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.975 0.025
I47 Paroxysmal tachycardia
0.000 0.975 0.025
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.975 0.025
I46.0 Cardiac arrest with successful resuscitation
0.000 0.975 0.025
I06.1 Rheumatic aortic insufficiency
0.000 0.976 0.024
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.976 0.024
I06.8 Other rheumatic aortic valve diseases
0.000 0.976 0.024
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.976 0.024
I33.9 Acute endocarditis, unspecified
0.000 0.976 0.024
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.976 0.024
I33.0 Acute and subacute infective endocarditis
0.000 0.976 0.024
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.976 0.023
I46.9 Cardiac arrest, unspecified
0.000 0.977 0.023
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.977 0.023
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.977 0.023
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.977 0.023
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.977 0.023
I97.1 Other functional disturbances following cardiac surgery
0.000 0.977 0.023
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.977 0.023
I97.0 Postcardiotomy syndrome
0.000 0.977 0.023
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.977 0.023
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.977 0.022
I47.0 Reentry ventricular arrhythmia
0.000 0.978 0.022
I06.0 Rheumatic aortic stenosis
0.000 0.978 0.022
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.978 0.022
I08.9 Multiple valve disease, unspecified
0.000 0.978 0.022
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.978 0.022
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.978 0.022
I98.0 Cardiovascular syphilis
0.000 0.978 0.022
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.978 0.022
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.978 0.022
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.978 0.021
I08.8 Other multiple valve diseases
0.000 0.979 0.021
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.979 0.021
M16 Coxarthrosis [arthrosis of hip]
0.021 0.979 0.000
I73.8 Other specified peripheral vascular diseases
0.000 0.980 0.020
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.980 0.020
I65.2 Occlusion and stenosis of carotid artery
0.000 0.980 0.020
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.980 0.020
I63.8 Other cerebral infarction
0.000 0.980 0.019
I77.6 Arteritis, unspecified
0.001 0.981 0.019
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.981 0.019
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.981 0.018
I05.9 Mitral valve disease, unspecified
0.000 0.981 0.018
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.981 0.018
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.982 0.018
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.982 0.018
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.982 0.018
M16.9 Coxarthrosis, unspecified
0.018 0.982 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.983 0.017
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.983 0.017
I63.9 Cerebral infarction, unspecified
0.000 0.983 0.017
M16.7 Other secondary coxarthrosis
0.017 0.983 0.000
I08.0 Disorders of both mitral and aortic valves
0.000 0.983 0.017
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.983 0.017
I20-I25 Ischaemic heart diseases
0.000 0.983 0.017
M16.5 Other posttraumatic coxarthrosis
0.016 0.984 0.000
I31.3 Pericardial effusion (noninflammatory)
0.000 0.985 0.015
M16.4 Posttraumatic coxarthrosis, bilateral
0.015 0.985 0.000
I28 Other diseases of pulmonary vessels
0.001 0.985 0.014
I51 Complications and ill-defined descriptions of heart disease
0.000 0.985 0.015
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.015 0.985 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.985 0.015
I73.0 Raynaud's syndrome
0.000 0.986 0.014
M16.3 Other dysplastic coxarthrosis
0.014 0.986 0.000
I25 Chronic ischaemic heart disease
0.000 0.986 0.014
M16.6 Other secondary coxarthrosis, bilateral
0.014 0.986 0.000
I95 Hypotension
0.000 0.987 0.013
I78.1 Naevus, nonneoplastic
0.000 0.987 0.013
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.987 0.013
M16.0 Primary coxarthrosis, bilateral
0.013 0.987 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.988 0.012
I23 Certain current complications following acute myocardial infarction
0.000 0.988 0.012
D18.0 Haemangioma, any site
0.012 0.988 0.000
I60 Subarachnoid haemorrhage
0.002 0.988 0.010
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.989 0.011
I51.0 Cardiac septal defect, acquired
0.000 0.989 0.011
I51.5 Myocardial degeneration
0.000 0.989 0.011
I95.8 Other hypotension
0.000 0.989 0.011
I28.1 Aneurysm of pulmonary artery
0.001 0.989 0.010
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.989 0.011
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.989 0.010
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.989 0.010
I25.4 Coronary artery aneurysm
0.000 0.989 0.010
I51.7 Cardiomegaly
0.000 0.990 0.010
I28.8 Other specified diseases of pulmonary vessels
0.001 0.990 0.010
I47.2 Ventricular tachycardia
0.000 0.990 0.010
I26 Pulmonary embolism
0.001 0.990 0.009
I25.1 Atherosclerotic heart disease
0.000 0.990 0.010
I51.6 Cardiovascular disease, unspecified
0.000 0.990 0.010
I25.6 Silent myocardial ischaemia
0.000 0.990 0.010
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.990 0.009
I88 Nonspecific lymphadenitis
0.000 0.990 0.010
I82 Other venous embolism and thrombosis
0.000 0.991 0.009
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.991 0.009
I85 Oesophageal varices
0.000 0.991 0.009
I24 Other acute ischaemic heart diseases
0.000 0.991 0.009
E70-E90 Metabolic disorders
0.000 0.991 0.009
T81.3 Disruption of operation wound, not elsewhere classified
0.009 0.991 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.991 0.009
I95.0 Idiopathic hypotension
0.000 0.991 0.009
I51.4 Myocarditis, unspecified
0.000 0.991 0.009
I60.4 Subarachnoid haemorrhage from basilar artery
0.001 0.991 0.008
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.991 0.008
I51.9 Heart disease, unspecified
0.000 0.991 0.009
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.991 0.008
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.991 0.008
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.991 0.008
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.991 0.008
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.991 0.008
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.991 0.008
I81 Portal vein thrombosis
0.000 0.991 0.009
I60.5 Subarachnoid haemorrhage from vertebral artery
0.001 0.991 0.007
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.992 0.008
I49 Other cardiac arrhythmias
0.000 0.992 0.008
I23.8 Other current complications following acute myocardial infarction
0.000 0.992 0.008
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.001 0.992 0.007
I25.5 Ischaemic cardiomyopathy
0.000 0.992 0.008
I25.3 Aneurysm of heart
0.000 0.992 0.008
I82.8 Embolism and thrombosis of other specified veins
0.000 0.992 0.008
R26.8 Other and unspecified abnormalities of gait and mobility
0.000 0.992 0.008
I88.8 Other nonspecific lymphadenitis
0.000 0.992 0.008
S92.00 Fracture of calcaneus (closed)
0.000 0.992 0.008
I60.8 Other subarachnoid haemorrhage
0.001 0.992 0.007
I27 Other pulmonary heart diseases
0.001 0.992 0.007
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.002 0.992 0.006
I85.9 Oesophageal varices without bleeding
0.000 0.992 0.008
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.992 0.008
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.002 0.992 0.006
I95.2 Hypotension due to drugs
0.000 0.992 0.007
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.001 0.992 0.006
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.001 0.992 0.006
I85.0 Oesophageal varices with bleeding
0.000 0.992 0.007
I82.2 Embolism and thrombosis of vena cava
0.000 0.992 0.007
I25.2 Old myocardial infarction
0.000 0.993 0.007
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.001 0.993 0.006
E84 Cystic fibrosis
0.000 0.993 0.007
I86 Varicose veins of other sites
0.000 0.993 0.007
I95.1 Orthostatic hypotension
0.000 0.993 0.007
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.993 0.007
I82.3 Embolism and thrombosis of renal vein
0.000 0.993 0.007
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.001 0.993 0.007
I20 Angina pectoris
0.000 0.993 0.007
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.993 0.007
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.993 0.007
E72 Other disorders of amino-acid metabolism
0.000 0.993 0.007
I82.1 Thrombophlebitis migrans
0.000 0.993 0.007
E76 Disorders of glycosaminoglycan metabolism
0.000 0.993 0.007
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.993 0.007
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.993 0.007
E70 Disorders of aromatic amino-acid metabolism
0.000 0.993 0.007
E85 Amyloidosis
0.000 0.993 0.007
I82.0 Budd-Chiari syndrome
0.000 0.993 0.007
E77 Disorders of glycoprotein metabolism
0.000 0.993 0.007
I24.1 Dressler's syndrome
0.000 0.993 0.007
E74 Other disorders of carbohydrate metabolism
0.000 0.993 0.007
Z45.8 Adjustment and management of other implanted devices
0.000 0.993 0.007
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.993 0.007
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.993 0.007
E79 Disorders of purine and pyrimidine metabolism
0.000 0.993 0.007
H81.0 Meniere's disease
0.000 0.993 0.007
S92.0 Fracture of calcaneus
0.000 0.993 0.007
E88 Other metabolic disorders
0.000 0.993 0.007
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.993 0.006
I49.1 Atrial premature depolarisation
0.000 0.993 0.006
E73 Lactose intolerance
0.000 0.994 0.006
I50 Heart failure
0.000 0.994 0.006
I22 Subsequent myocardial infarction
0.000 0.994 0.006
I20.0 Unstable angina
0.000 0.994 0.006
I49.2 Junctional premature depolarisation
0.000 0.994 0.006
E80.4 Gilbert's syndrome
0.000 0.994 0.006
I21 Acute myocardial infarction
0.000 0.994 0.006
I49.4 Other and unspecified premature depolarisation
0.000 0.994 0.006
I27.1 Kyphoscoliotic heart disease
0.001 0.994 0.005
I86.3 Vulval varices
0.000 0.994 0.006
S92 Fracture of foot, except ankle
0.000 0.994 0.006
I86.4 Gastric varices
0.000 0.994 0.006
I87 Other disorders of veins
0.000 0.994 0.006
I49.0 Ventricular fibrillation and flutter
0.000 0.994 0.006
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.994 0.006
I73.9 Peripheral vascular disease, unspecified
0.000 0.994 0.006
J69.0 Pneumonitis due to food and vomit
0.006 0.994 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.994 0.005
E80.6 Other disorders of bilirubin metabolism
0.000 0.994 0.005
I49.8 Other specified cardiac arrhythmias
0.000 0.994 0.006
E72.0 Disorders of amino-acid transport
0.000 0.994 0.005
E84.8 Cystic fibrosis with other manifestations
0.000 0.994 0.005
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.994 0.005
D18 Haemangioma and lymphangioma, any site
0.006 0.994 0.000
I86.0 Sublingual varices
0.000 0.994 0.005
E80.5 Crigler-Najjar syndrome
0.000 0.994 0.005
E80.3 Defects of catalase and peroxydase
0.000 0.994 0.005
E80.0 Hereditary erythropoietic porphyria
0.000 0.994 0.005
E85.8 Other amyloidosis
0.000 0.994 0.005
E80.1 Porphyria cutanea tarda
0.000 0.995 0.005
S92.3 Fracture of metatarsal bone
0.000 0.995 0.005
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.995 0.005
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.995 0.005
E72.5 Disorders of glycine metabolism
0.000 0.995 0.005
E72.4 Disorders of ornithine metabolism
0.000 0.995 0.005
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.995 0.005
E72.2 Disorders of urea cycle metabolism
0.000 0.995 0.005
I27.8 Other specified pulmonary heart diseases
0.001 0.995 0.005
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.995 0.005
J35.8 Other chronic diseases of tonsils and adenoids
0.000 0.995 0.005
S92.2 Fracture of other tarsal bone(s)
0.000 0.995 0.005
E71.3 Disorders of fatty-acid metabolism
0.000 0.995 0.005
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.995 0.005
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.995 0.005
E71.0 Maple-syrup-urine disease
0.000 0.995 0.005
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.995 0.005
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.995 0.005
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.995 0.005
E76.2 Other mucopolysaccharidoses
0.000 0.995 0.005
E76.1 Mucopolysaccharidosis, type II
0.000 0.995 0.005
E76.0 Mucopolysaccharidosis, type I
0.000 0.995 0.005
E85.3 Secondary systemic amyloidosis
0.000 0.995 0.005
I86.8 Varicose veins of other specified sites
0.000 0.995 0.005
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.995 0.005
S92.30 Fracture of metatarsal bone (closed)
0.000 0.995 0.005
E88.2 Lipomatosis, not elsewhere classified
0.000 0.995 0.005
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.995 0.005
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.995 0.005
E70.2 Disorders of tyrosine metabolism
0.000 0.995 0.005
E70.1 Other hyperphenylalaninaemias
0.000 0.995 0.005
E70.0 Classical phenylketonuria
0.000 0.995 0.005
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.995 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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