TreeWAS – Variant ID: rs2161277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.978	0.022
H72 Perforation of tympanic membrane	0.000	0.985	0.015
M54.9 Dorsalgia, unspecified	0.014	0.986	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.013	0.987	0.000
M54 Dorsalgia	0.013	0.987	0.000
M54.56 Low back pain (Lumbar region)	0.013	0.987	0.000
M54.5 Low back pain	0.012	0.988	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.988	0.012
M54.94 Dorsalgia, unspecified (Thoracic region)	0.012	0.988	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.011	0.989	0.000
M54.1 Radiculopathy	0.011	0.989	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.011	0.989	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.989	0.011
H72.1 Attic perforation of tympanic membrane	0.000	0.989	0.011
M54.4 Lumbago with sciatica	0.011	0.989	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.989	0.010
M54.6 Pain in thoracic spine	0.010	0.990	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.990	0.010
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.010	0.990	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.010	0.990	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.010	0.990	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.010	0.990	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.010	0.990	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.010	0.990	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.010	0.990	0.000
H66 Suppurative and unspecified otitis media	0.000	0.990	0.010
H65-H75 Diseases of middle ear and mastoid	0.000	0.990	0.010
M54.14 Radiculopathy (Thoracic region)	0.009	0.990	0.000
M54.16 Radiculopathy (Lumbar region)	0.009	0.990	0.000
M54.50 Low back pain (Multiple sites in spine)	0.009	0.991	0.000
M54.8 Other dorsalgia	0.009	0.991	0.000
M54.0 Panniculitis affecting regions of neck and back	0.009	0.991	0.000
M54.12 Radiculopathy (Cervical region)	0.009	0.991	0.000
M54.19 Radiculopathy (Site unspecified)	0.009	0.991	0.000
M50.0 Cervical disk disorder with myelopathy	0.009	0.991	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.009	0.991	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.009	0.991	0.000
M54.54 Low back pain-Thoracic	0.009	0.991	0.000
M54.53 Low back pain-Cervicothoracic	0.009	0.991	0.000
M54.52 Low back pain-Cervical	0.009	0.991	0.000
M54.51 Low back pain-Occipit-atl-axl	0.009	0.991	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.009	0.991	0.000
M54.55 Low back pain (Thoracolumbar region)	0.008	0.991	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.008	0.992	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.008	0.992	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.008	0.992	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.008	0.992	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.008	0.992	0.000
H66.9 Otitis media, unspecified	0.000	0.992	0.008
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.008	0.992	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.008	0.992	0.000
M54.44 Lumbago with sciatica-Thoracic	0.008	0.992	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.008	0.992	0.000
M54.42 Lumbago with sciatica-Cervical	0.008	0.992	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.008	0.992	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.008	0.992	0.000
M54.69 Pain in thoracic spine-Site unspe	0.008	0.992	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.008	0.992	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.008	0.992	0.000
M54.66 Pain in thoracic spine-Lumbar	0.008	0.992	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.008	0.992	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.008	0.992	0.000
M54.62 Pain in thoracic spine-Cervical	0.008	0.992	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.008	0.992	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.008	0.992	0.000
M50 Cervical disk disorders	0.008	0.992	0.000
M54.3 Sciatica	0.008	0.992	0.000
Y57 Other and unspecified drugs and medicaments	0.008	0.992	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.993	0.007
H66.0 Acute suppurative otitis media	0.000	0.993	0.007
M54.46 Lumbago with sciatica (Lumbar region)	0.007	0.993	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.993	0.007
H68 Eustachian salpingitis and obstruction	0.000	0.993	0.007
H67 Otitis media in diseases classified elsewhere	0.000	0.993	0.007
M50-M54 Other dorsopathies	0.007	0.993	0.000
Y57.8 Other drugs and medicaments	0.007	0.993	0.000
H69 Other disorders of Eustachian tube	0.000	0.993	0.007
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.007	0.993	0.000
H70 Mastoiditis and related conditions	0.000	0.993	0.007
M54.57 Low back pain (Lumbosacral region)	0.007	0.993	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.993	0.007
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.007	0.993	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.007	0.993	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.007	0.993	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.007	0.993	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.007	0.993	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.007	0.993	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.007	0.993	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.007	0.993	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.007	0.993	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.007	0.993	0.000
M54.89 Other dorsalgia (Site unspecified)	0.007	0.993	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.007	0.993	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.007	0.993	0.000
M54.86 Other dorsalgia (Lumbar region)	0.007	0.993	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.007	0.993	0.000
M54.84 Other dorsalgia (Thoracic region)	0.007	0.993	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.007	0.993	0.000
M54.82 Other dorsalgia (Cervical region)	0.007	0.993	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.007	0.993	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.007	0.993	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.007	0.993	0.000
M50.3 Other cervical disk degeneration	0.007	0.993	0.000
M54.2 Cervicalgia	0.006	0.993	0.000
H65 Nonsuppurative otitis media	0.000	0.993	0.007
Y49.2 Other and unspecified antidepressants	0.006	0.993	0.000
Y43 Primarily systemic agents	0.007	0.993	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.994	0.006
Y57.6 Other diagnostic agents	0.006	0.994	0.000
H73 Other disorders of tympanic membrane	0.000	0.994	0.006
Y40 Systemic antibiotics	0.006	0.994	0.000
M50.9 Cervical disk disorder, unspecified	0.006	0.994	0.000
H74 Other disorders of middle ear and mastoid	0.000	0.994	0.006
I20.8 Other forms of angina pectoris	0.006	0.994	0.000
H71 Cholesteatoma of middle ear	0.000	0.994	0.006
Y57.9 Drug or medicament, unspecified	0.006	0.994	0.000
H65.2 Chronic serous otitis media	0.000	0.994	0.006
Y40.0 Penicillins	0.006	0.994	0.000
Y57.5 X-ray contrast media	0.006	0.994	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.006	0.994	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.006	0.994	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.006	0.994	0.000
M50.8 Other cervical disk disorders	0.006	0.994	0.000
M50.2 Other cervical disk displacement	0.006	0.994	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.006	0.994	0.000
M54.35 Sciatica (Thoracolumbar region)	0.006	0.994	0.000
M54.34 Sciatica-Thoracic	0.006	0.994	0.000
M54.33 Sciatica-Cervicothoracic	0.006	0.994	0.000
M54.32 Sciatica-Cervical	0.006	0.994	0.000
M54.31 Sciatica-Occipit-atl-axl	0.006	0.994	0.000
M54.30 Sciatica (Multiple sites in spine)	0.006	0.994	0.000
Y49.5 Other antipsychotics and neuroleptics	0.006	0.994	0.000
Y57.7 Vitamins, not elsewhere classified	0.006	0.994	0.000
Y57.4 Pharmaceutical excipients	0.006	0.994	0.000
Y57.3 Alcohol deterrents	0.006	0.994	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.006	0.994	0.000
Y57.1 Lipotropic drugs	0.006	0.994	0.000
Y57.0 Appetite depressants [anorectics]	0.006	0.994	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.006	0.994	0.000
Y43.3 Other antineoplastic drugs	0.006	0.994	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.994	0.005
Y40.9 Systemic antibiotic, unspecified	0.006	0.994	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.995	0.005
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.995	0.005
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.995	0.005
H68.1 Obstruction of Eustachian tube	0.000	0.995	0.005
H68.0 Eustachian salpingitis	0.000	0.995	0.005
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.995	0.005
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
H69.0 Patulous Eustachian tube	0.000	0.995	0.005
Y43.4 Immunosuppressive agents	0.005	0.995	0.000
Y43.1 Antineoplastic antimetabolites	0.005	0.995	0.000
Y59 Other and unspecified vaccines and biological substances	0.005	0.995	0.000
Y58 Bacterial vaccines	0.005	0.995	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.005	0.995	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.005	0.995	0.000
H70.8 Other mastoiditis and related conditions	0.000	0.995	0.005
H70.2 Petrositis	0.000	0.995	0.005
H70.1 Chronic mastoiditis	0.000	0.995	0.005
H70.0 Acute mastoiditis	0.000	0.995	0.005
H74.4 Polyp of middle ear	0.000	0.995	0.005
Y45.5 4-Aminophenol derivatives	0.005	0.995	0.000
M54.37 Sciatica (Lumbosacral region)	0.005	0.995	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
M54.39 Sciatica (Site unspecified)	0.005	0.995	0.000
Y49.9 Psychotropic drug, unspecified	0.005	0.995	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
Y49.7 Psychostimulants with abuse potential	0.005	0.995	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.005	0.995	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.995	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.005	0.995	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
Y48 Anaesthetics and therapeutic gases	0.005	0.995	0.000
H70.9 Mastoiditis, unspecified	0.000	0.995	0.005
Y54.4 Loop [high-ceiling] diuretics	0.005	0.995	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.005	0.995	0.000
M54.27 Cervicalgia-Lumbosacral	0.005	0.995	0.000
M54.26 Cervicalgia-Lumbar	0.005	0.995	0.000
M54.25 Cervicalgia-Thoracolumbar	0.005	0.995	0.000
M54.24 Cervicalgia-Thoracic	0.005	0.995	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.005	0.995	0.000
M54.20 Cervicalgia-Mult site	0.005	0.995	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.995	0.005
H65.0 Acute serous otitis media	0.000	0.995	0.005
Y45.8 Other analgesics and antipyretics	0.005	0.995	0.000
K62.1 Rectal polyp	0.000	0.995	0.005
Y46 Antiepileptics and anti-Parkinsonism drugs	0.005	0.995	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.995	0.005
H69.8 Other specified disorders of Eustachian tube	0.000	0.995	0.005
Y43.9 Primarily systemic agent, unspecified	0.005	0.995	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.005	0.995	0.000
Y43.6 Enzymes, not elsewhere classified	0.005	0.995	0.000
Y43.5 Acidifying and alkalising agents	0.005	0.995	0.000
Y43.2 Antineoplastic natural products	0.005	0.995	0.000
M54.36 Sciatica (Lumbar region)	0.005	0.995	0.000
Y44 Agents primarily affecting blood constituents	0.005	0.995	0.000
Y45.0 Opioids and related analgesics	0.005	0.995	0.000
H73.1 Chronic myringitis	0.000	0.995	0.005
H73.0 Acute myringitis	0.000	0.995	0.005
Y40.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
Y40.6 Rifamycins	0.005	0.995	0.000
Y40.5 Aminoglycosides	0.005	0.995	0.000
Y40.4 Tetracyclines	0.005	0.995	0.000
Y40.2 Chloramphenicol group	0.005	0.995	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.995	0.005
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.995	0.005
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.005	0.995	0.000
H61 Other disorders of external ear	0.000	0.995	0.005
Y54.3 Benzothiadiazine derivatives	0.005	0.995	0.000
Y43.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
M53 Other dorsopathies, not elsewhere classified	0.005	0.995	0.000
H74.0 Tympanosclerosis	0.000	0.995	0.005
Y60.0 During surgical operation	0.005	0.995	0.000
R29.6 Tendency to fall, not elsewhere classified	0.000	0.995	0.005
Y52 Agents primarily affecting the cardiovascular system	0.005	0.995	0.000
H74.1 Adhesive middle ear disease	0.000	0.995	0.004
Y45.2 Propionic acid derivatives	0.005	0.995	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.004	0.995	0.000
Y54.9 Mineral salts, not elsewhere classified	0.004	0.995	0.000
Y54.8 Agents affecting uric acid metabolism	0.004	0.995	0.000
Y54.7 Agents affecting calcification	0.004	0.995	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.004	0.995	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.004	0.995	0.000
Y54.0 Mineralocorticoids	0.004	0.995	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.995	0.004
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.004	0.995	0.000
Y45.4 Antirheumatics	0.004	0.995	0.000
Y54.5 Other diuretics	0.004	0.995	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
Y40.8 Other systemic antibiotics	0.004	0.996	0.000
H61.8 Other specified disorders of external ear	0.000	0.996	0.004
Y60-Y69 Misadventures to patients during surgical and medical care	0.004	0.996	0.000
Chapter VIII Diseases of the ear and mastoid process	0.000	0.996	0.004
H65.3 Chronic mucoid otitis media	0.000	0.996	0.004
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.004	0.996	0.000
Y40.3 Macrolides	0.004	0.996	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.996	0.004
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
Y45.1 Salicylates	0.004	0.996	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.996	0.004
H60-H62 Diseases of external ear	0.000	0.996	0.004
H61.1 Non-infective disorders of pinna	0.000	0.996	0.004
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.996	0.004
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.004	0.996	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.996	0.004
Y65 Other misadventures during surgical and medical care	0.004	0.996	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.996	0.004
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.996	0.004
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.004	0.996	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.004	0.996	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.004	0.996	0.000
Y47.4 Bromine compounds	0.004	0.996	0.000
Y47.3 Paraldehyde	0.004	0.996	0.000
Y47.2 Chloral derivatives	0.004	0.996	0.000
Y47.1 Benzodiazepines	0.004	0.996	0.000
Y47.0 Barbiturates, not elsewhere classified	0.004	0.996	0.000
Y50.9 Central nervous system stimulant, unspecified	0.004	0.996	0.000
Y50.8 Other central nervous system stimulants	0.004	0.996	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.004	0.996	0.000
Y50.1 Opioid receptor antagonists	0.004	0.996	0.000
Y50.0 Analeptics	0.004	0.996	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
Y55.5 Anticommon cold drugs	0.004	0.996	0.000
Y55.4 Expectorants	0.004	0.996	0.000
Y55.3 Antitussives	0.004	0.996	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
Y55.0 Oxytocic drugs	0.004	0.996	0.000
Y58.9 Other and unspecified bacterial vaccines	0.004	0.996	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.004	0.996	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.004	0.996	0.000
Y58.5 Diphtheria vaccine	0.004	0.996	0.000
Y58.4 Tetanus vaccine	0.004	0.996	0.000
Y58.3 Plague vaccine	0.004	0.996	0.000
Y58.2 Cholera vaccine	0.004	0.996	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.004	0.996	0.000
Y58.0 BCG vaccine	0.004	0.996	0.000
Y59.9 Vaccine or biological substance, unspecified	0.004	0.996	0.000
Y59.8 Other specified vaccines and biological substances	0.004	0.996	0.000
Y59.3 Immunoglobulin	0.004	0.996	0.000
Y59.2 Protozoal vaccines	0.004	0.996	0.000
Y59.1 Rickettsial vaccines	0.004	0.996	0.000
Y59.0 Viral vaccines	0.004	0.996	0.000
Y65.8 Other specified misadventures during surgical and medical care	0.004	0.996	0.000
T93 Sequelae of injuries of lower limb	0.000	0.996	0.004
Y48.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
Y53.7 Emetics	0.004	0.996	0.000
Y53.6 Antidiarrhoeal drugs	0.004	0.996	0.000
Y53.5 Digestants	0.004	0.996	0.000
Y53.3 Saline and osmotic laxatives	0.004	0.996	0.000
Y53.2 Stimulant laxatives	0.004	0.996	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.000
Y53.0 Histamine H2-receptor antagonists	0.004	0.996	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
Y51.0 Anticholinesterase agents	0.004	0.996	0.000
Chapter XX External causes of morbidity and mortality	0.004	0.996	0.000
Y48.5 Therapeutic gases	0.004	0.996	0.000
Y48.4 Anaesthetic, unspecified	0.004	0.996	0.000
Y48.1 Parenteral anaesthetics	0.004	0.996	0.000
Y48.0 Inhaled anaesthetics	0.004	0.996	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.996	0.004
S82.40 Fracture of fibula alone (closed)	0.000	0.996	0.004
Y53.4 Other laxatives	0.004	0.996	0.000
M54.59 Low back pain (Site unspecified)	0.004	0.996	0.000
W51.9 Unspecified place	0.004	0.996	0.000
Y46.8 Antispasticity drugs	0.004	0.996	0.000
Y46.7 Anti-Parkinsonism drugs	0.004	0.996	0.000
Y46.6 Other and unspecified antiepileptics	0.004	0.996	0.000
Y46.5 Valproic acid	0.004	0.996	0.000
Y46.3 Deoxybarbiturates	0.004	0.996	0.000
Y46.2 Hydantoin derivatives	0.004	0.996	0.000
Y46.1 Oxazolidinediones	0.004	0.996	0.000
Y46.0 Succinimides	0.004	0.996	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.004	0.996	0.000
H61.2 Impacted cerumen	0.000	0.996	0.004
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.004	0.996	0.000
Y44.7 Plasma substitutes	0.004	0.996	0.000
Y44.6 Natural blood and blood products	0.004	0.996	0.000
Y44.5 Thrombolytic drugs	0.004	0.996	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.004	0.996	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.004	0.996	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.004	0.996	0.000
W50-W64 Exposure to animate mechanical forces	0.004	0.996	0.000
W51 Striking against or bumped into by another person	0.004	0.996	0.000
Y56.9 Topical agent, unspecified	0.003	0.996	0.000
Y56.8 Other topical agents	0.003	0.996	0.000
Y56.7 Dental drugs, topically applied	0.003	0.996	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.003	0.996	0.000
Y56.5 Ophthalmological drugs and preparations	0.003	0.996	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.996	0.000
Y56.3 Emollients, demulcents and protectants	0.003	0.996	0.000
Y56.2 Local astringents and local detergents	0.003	0.996	0.000
Y56.1 Antipruritics	0.003	0.996	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.996	0.004
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
M53.9 Dorsopathy, unspecified	0.003	0.996	0.000
M53.8 Other specified dorsopathies	0.003	0.996	0.000
M53.2 Spinal instabilities	0.003	0.996	0.000
M53.1 Cervicobrachial syndrome	0.003	0.996	0.000
M53.0 Cervicocranial syndrome	0.003	0.996	0.000
Y48.3 Local anaesthetics	0.003	0.996	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.996	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.996	0.000
Y52.7 Peripheral vasodilators	0.003	0.996	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.996	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.004	0.996	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.004	0.996	0.000
H61.0 Perichondritis of external ear	0.000	0.996	0.004
M54.22 Cervicalgia (Cervical region)	0.003	0.996	0.000
T93.1 Sequelae of fracture of femur	0.000	0.996	0.003
Y46.4 Iminostilbenes	0.003	0.996	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.003	0.997	0.000
Y41.4 Anthelminthics	0.003	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.003	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
Y41.1 Antimycobacterial drugs	0.003	0.997	0.000
Y41.0 Sulphonamides	0.003	0.997	0.000
W08.0 Home	0.003	0.997	0.000
Y64 Contaminated medical or biological substances	0.003	0.997	0.000
Y63 Failure in dosage during surgical and medical care	0.003	0.997	0.000
Y62 Failure of sterile precautions during surgical and medical care	0.003	0.997	0.000
Y61 Foreign object accidentally left in body during surgical and medical care	0.003	0.997	0.000
Y69 Unspecified misadventure during surgical and medical care	0.003	0.997	0.000
Y66 Nonadministration of surgical and medical care	0.003	0.997	0.000
Y60.9 During unspecified surgical and medical care	0.003	0.997	0.000
Y60.8 During other surgical and medical care	0.003	0.997	0.000
Y60.7 During administration of enema	0.003	0.997	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.003	0.997	0.000
Y60.5 During heart catheterisation	0.003	0.997	0.000
Y60.3 During injection or immunisation	0.003	0.997	0.000
Y60.2 During kidney dialysis or other perfusion	0.003	0.997	0.000
Y60.1 During infusion or transfusion	0.003	0.997	0.000
H80-H83 Diseases of inner ear	0.000	0.997	0.003
X50-X57 Overexertion, travel and privation	0.003	0.997	0.000
V20-V29 Motorcycle rider injured in transport accident	0.003	0.997	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.997	0.003
X10-X19 Contact with heat and hot substances	0.003	0.997	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
Y44.2 Anticoagulants	0.003	0.997	0.000
V10-V19 Pedal cyclist injured in transport accident	0.003	0.997	0.000
V40-V49 Car occupant injured in transport accident	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
Y65.5 Performance of inappropriate operation	0.003	0.997	0.000
Y65.4 Failure to introduce or to remove other tube or instrument	0.003	0.997	0.000
Y65.3 Endotracheal tube wrongly placed during anaesthetic procedure	0.003	0.997	0.000
Y65.2 Failure in suture or ligature during surgical operation	0.003	0.997	0.000
Y65.1 Wrong fluid used in infusion	0.003	0.997	0.000
Y65.0 Mismatched blood used in transfusion	0.003	0.997	0.000
H81 Disorders of vestibular function	0.000	0.997	0.003
V01-V09 Pedestrian injured in transport accident	0.003	0.997	0.000
W20-W49 Exposure to inanimate mechanical forces	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
K70.9 Alcoholic liver disease, unspecified	0.003	0.997	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.997	0.003
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
W75-W84 Other accidental threats to breathing	0.003	0.997	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.997	0.003
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.997	0.003
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.997	0.003
T93.0 Sequelae of open wound of lower limb	0.000	0.997	0.003
N43.3 Hydrocele, unspecified	0.003	0.997	0.000
W55 Bitten or struck by other mammals	0.003	0.997	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.003	0.997	0.000
Y60.4 During endoscopic examination	0.003	0.997	0.000
Y35-Y36 Legal intervention and operations of war	0.003	0.997	0.000
Y10-Y34 Event of undetermined intent	0.003	0.997	0.000
X85-X99 Assault	0.003	0.997	0.000
X30-X39 Exposure to forces of nature	0.003	0.997	0.000
X00-X09 Exposure to smoke, fire and flames	0.003	0.997	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.003	0.997	0.000
W65-W74 Accidental drowning and submersion	0.003	0.997	0.000
V98-V99 Other and unspecified transport accidents	0.003	0.997	0.000
V95-V97 Air and space transport accidents	0.003	0.997	0.000
V90-V94 Water transport accidents	0.003	0.997	0.000
V80-V89 Other land transport accidents	0.003	0.997	0.000
V70-V79 Bus occupant injured in transport accident	0.003	0.997	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.003	0.997	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.003	0.997	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.003	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
M54.29 Cervicalgia-Site unspe	0.002	0.997	0.001
R60.0 Localised oedema	0.000	0.997	0.003
X40-X49 Accidental poisoning by and exposure to noxious substances	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.997	0.003
W29 Contact with other powered hand tools and household machinery	0.003	0.997	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.003	0.997	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus	0.003	0.997	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.003	0.997	0.000
Y81 General- and plastic-surgery devices associated with adverse incidents	0.003	0.997	0.000
Y80 Physical medicine devices associated with adverse incidents	0.003	0.997	0.000
Y78 Radiological devices associated with adverse incidents	0.003	0.997	0.000
Y75 Neurological devices associated with adverse incidents	0.003	0.997	0.000
Y74 General hospital and personal-use devices associated with adverse incidents	0.003	0.997	0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.003	0.997	0.000
Y72 Otorhinolaryngological devices associated with adverse incidents	0.003	0.997	0.000
Y71 Cardiovascular devices associated with adverse incidents	0.003	0.997	0.000
Y70 Anaesthesiology devices associated with adverse incidents	0.003	0.997	0.000
D12.8 Rectum	0.000	0.997	0.003
W64 Exposure to other and unspecified animate mechanical forces	0.003	0.997	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.003	0.997	0.000
W59 Bitten or crushed by other reptiles	0.003	0.997	0.000
W58 Bitten or struck by crocodile or alligator	0.003	0.997	0.000
W56 Contact with marine animal	0.003	0.997	0.000
W54 Bitten or struck by dog	0.003	0.997	0.000
W53 Bitten by rat	0.003	0.997	0.000
W52 Crushed, pushed and stepped on by crowd or human stampede	0.003	0.997	0.000
W51.8 Other specified place	0.003	0.997	0.000
W51.3 Sports and athletics area	0.003	0.997	0.000
W51.0 Home	0.003	0.997	0.000
W51.7 Farm	0.003	0.997	0.000
W51.6 Industrial and construction area	0.003	0.997	0.000
W51.5 Trade and service area	0.003	0.997	0.000
W51.4 Street and highway	0.003	0.997	0.000
W51.2 School, other institution and public administrative area	0.003	0.997	0.000
W51.1 Residential institution	0.003	0.997	0.000
X51 Travel and motion	0.003	0.997	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.003	0.997	0.000
M53.09 Cervicocranial syndrome-Site unspe	0.003	0.997	0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.003	0.997	0.000
M53.07 Cervicocranial syndrome-Lumbosacral	0.003	0.997	0.000
M53.06 Cervicocranial syndrome-Lumbar	0.003	0.997	0.000
M53.05 Cervicocranial syndrome-Thoracolumbar	0.003	0.997	0.000
M53.04 Cervicocranial syndrome-Thoracic	0.003	0.997	0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.003	0.997	0.000
M53.02 Cervicocranial syndrome (Cervical region)	0.003	0.997	0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.003	0.997	0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.003	0.997	0.000
M53.19 Cervicobrachial syndrome-Site unspe	0.003	0.997	0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.003	0.997	0.000
M53.17 Cervicobrachial syndrome-Lumbosacral	0.003	0.997	0.000
M53.16 Cervicobrachial syndrome-Lumbar	0.003	0.997	0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.003	0.997	0.000
M53.14 Cervicobrachial syndrome-Thoracic	0.003	0.997	0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations