TreeWAS – Variant ID: rs216195

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.004	0.996
I20 Angina pectoris	0.000	0.007	0.993
I20.9 Angina pectoris, unspecified	0.000	0.012	0.988
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.019	0.981
I25.5 Ischaemic cardiomyopathy	0.000	0.057	0.943
I20.8 Other forms of angina pectoris	0.000	0.070	0.930
I22 Subsequent myocardial infarction	0.000	0.118	0.882
I25.3 Aneurysm of heart	0.000	0.153	0.847
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.169	0.831
I22.8 Subsequent myocardial infarction of other sites	0.000	0.184	0.816
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.217	0.783
I23 Certain current complications following acute myocardial infarction	0.000	0.221	0.779
I24 Other acute ischaemic heart diseases	0.000	0.232	0.768
I25.2 Old myocardial infarction	0.000	0.245	0.755
I25.4 Coronary artery aneurysm	0.000	0.252	0.748
I21 Acute myocardial infarction	0.000	0.278	0.722
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I24.8 Other forms of acute ischaemic heart disease	0.000	0.318	0.682
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.340	0.660
I20.0 Unstable angina	0.000	0.344	0.656
I23.8 Other current complications following acute myocardial infarction	0.000	0.376	0.624
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.441	0.559
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.441	0.559
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.441	0.559
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.441	0.559
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.441	0.559
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.441	0.559
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.441	0.559
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.470	0.530
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.480	0.520
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.482	0.517
I24.1 Dressler's syndrome	0.000	0.489	0.511
I21.9 Acute myocardial infarction, unspecified	0.000	0.491	0.509
I20.1 Angina pectoris with documented spasm	0.000	0.492	0.508
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.549	0.451
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.554	0.446
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.556	0.444
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.558	0.442
I21.4 Acute subendocardial myocardial infarction	0.000	0.571	0.429
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.602	0.398
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.952	0.048
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.959	0.041
I72 Other aneurysm	0.000	0.967	0.033
I72.4 Aneurysm of artery of lower extremity	0.000	0.968	0.032
I72.3 Aneurysm of iliac artery	0.000	0.968	0.032
I72.8 Aneurysm of other specified arteries	0.000	0.969	0.031
Z95.1 Presence of aortocoronary bypass graft	0.000	0.971	0.029
I72.2 Aneurysm of renal artery	0.000	0.974	0.026
I72.9 Aneurysm of unspecified site	0.000	0.974	0.026
F33.9 Recurrent depressive disorder, unspecified	0.000	0.974	0.026
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.976	0.023
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.976	0.023
I72.1 Aneurysm of artery of upper extremity	0.000	0.978	0.022
F33 Recurrent depressive disorder	0.000	0.978	0.022
I72.0 Aneurysm of carotid artery	0.000	0.980	0.020
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.981	0.019
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.983	0.017
F30-F39 Mood [affective] disorders	0.000	0.983	0.017
F33.8 Other recurrent depressive disorders	0.000	0.984	0.016
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.984	0.016
M43.1 Spondylolisthesis	0.000	0.984	0.016
F30 Manic episode	0.000	0.984	0.016
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.985	0.015
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.986	0.014
F31 Bipolar affective disorder	0.000	0.986	0.014
F39 Unspecified mood [affective] disorder	0.000	0.986	0.014
F30.0 Hypomania	0.000	0.986	0.014
F30.9 Manic episode, unspecified	0.000	0.986	0.013
F31.9 Bipolar affective disorder, unspecified	0.000	0.987	0.013
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.987	0.013
F30.2 Mania with psychotic symptoms	0.000	0.988	0.012
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.988	0.012
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.988	0.012
M43.19 Spondylolisthesis (Site unspecified)	0.000	0.988	0.012
F38 Other mood [affective] disorders	0.000	0.988	0.012
F34 Persistent mood [affective] disorders	0.000	0.988	0.012
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.000	0.988	0.011
M43.15 Spondylolisthesis (Thoracolumbar region)	0.000	0.988	0.011
M43.14 Spondylolisthesis (Thoracic region)	0.000	0.988	0.011
M43.13 Spondylolisthesis (Cervicothoracic region)	0.000	0.988	0.011
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.000	0.988	0.011
M43.10 Spondylolisthesis (Multiple sites in spine)	0.000	0.988	0.011
F30.8 Other manic episodes	0.000	0.988	0.011
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.989	0.011
F31.7 Bipolar affective disorder, currently in remission	0.000	0.989	0.011
N75.0 Cyst of Bartholin's gland	0.000	0.989	0.011
M43.12 Spondylolisthesis (Cervical region)	0.000	0.989	0.011
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.989	0.010
F30.1 Mania without psychotic symptoms	0.000	0.990	0.010
Z35 Supervision of high-risk pregnancy	0.000	0.990	0.010
Z35.5 Supervision of elderly primigravida	0.000	0.990	0.010
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.991	0.009
F31.8 Other bipolar affective disorders	0.000	0.991	0.009
C53.9 Cervix uteri, unspecified	0.009	0.991	0.000
F38.8 Other specified mood [affective] disorders	0.000	0.991	0.009
F38.1 Other recurrent mood [affective] disorders	0.000	0.991	0.009
F38.0 Other single mood [affective] disorders	0.000	0.991	0.009
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.991	0.009
F34.8 Other persistent mood [affective] disorders	0.000	0.991	0.009
F34.0 Cyclothymia	0.000	0.991	0.009
Z72.0 Tobacco use	0.000	0.991	0.009
F34.1 Dysthymia	0.000	0.991	0.009
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.991	0.008
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.009	0.991	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.992	0.008
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.992	0.008
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.992	0.008
K70.9 Alcoholic liver disease, unspecified	0.008	0.992	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.992	0.008
D47.3 Essential (haemorrhagic) thrombocythaemia	0.008	0.992	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.992	0.008
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.992	0.008
R61.9 Hyperhidrosis, unspecified	0.000	0.992	0.008
Chapter IX Diseases of the circulatory system	0.000	0.992	0.008
K75.4 Autoimmune hepatitis	0.000	0.993	0.007
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.993	0.007
Z35.6 Supervision of very young primigravida	0.000	0.993	0.007
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.993	0.007
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.993	0.007
K70.4 Alcoholic hepatic failure	0.007	0.993	0.000
I70.0 Atherosclerosis of aorta	0.000	0.993	0.007
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.993	0.007
M43 Other deforming dorsopathies	0.000	0.993	0.007
K70 Alcoholic liver disease	0.007	0.993	0.000
I70 Atherosclerosis	0.000	0.993	0.007
K70.0 Alcoholic fatty liver	0.007	0.993	0.000
C53 Malignant neoplasm of cervix uteri	0.006	0.994	0.000
C53.0 Endocervix	0.006	0.994	0.000
M87.9 Osteonecrosis, unspecified	0.006	0.994	0.000
I00-I02 Acute rheumatic fever	0.000	0.994	0.006
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.994	0.006
I85.9 Oesophageal varices without bleeding	0.006	0.994	0.000
A63.0 Anogenital (venereal) warts	0.000	0.995	0.005
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.995	0.005
N75 Diseases of Bartholin's gland	0.000	0.995	0.005
M43.6 Torticollis	0.000	0.995	0.005
M43.9 Deforming dorsopathy, unspecified	0.000	0.995	0.005
M43.8 Other specified deforming dorsopathies	0.000	0.995	0.005
M43.5 Other recurrent vertebral subluxation	0.000	0.995	0.005
M43.4 Other recurrent atlantoaxial subluxation	0.000	0.995	0.005
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.000	0.995	0.005
I70.8 Atherosclerosis of other arteries	0.000	0.995	0.005
I70.9 Generalised and unspecified atherosclerosis	0.000	0.995	0.005
I71 Aortic aneurysm and dissection	0.000	0.995	0.005
M87 Osteonecrosis	0.005	0.995	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.995	0.005
C53.8 Overlapping lesion of cervix uteri	0.005	0.995	0.000
C53.1 Exocervix	0.005	0.995	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.995	0.005
Z35.8 Supervision of other high-risk pregnancies	0.000	0.995	0.005
K70.3 Alcoholic cirrhosis of liver	0.005	0.995	0.000
K70.1 Alcoholic hepatitis	0.005	0.995	0.000
M43.0 Spondylolysis	0.000	0.995	0.004
M54.64 Pain in thoracic spine (Thoracic region)	0.005	0.995	0.000
I00 Rheumatic fever without mention of heart involvement	0.000	0.995	0.004
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.004	0.995	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.004	0.995	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.004	0.995	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.004	0.995	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.004	0.995	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.004	0.995	0.000
K75 Other inflammatory liver diseases	0.000	0.995	0.005
K70.2 Alcoholic fibrosis and sclerosis of liver	0.004	0.995	0.000
M43.2 Other fusion of spine	0.000	0.995	0.004
M87.8 Other osteonecrosis	0.004	0.995	0.000
I70.1 Atherosclerosis of renal artery	0.000	0.995	0.004
I02 Rheumatic chorea	0.000	0.996	0.004
I01 Rheumatic fever with heart involvement	0.000	0.996	0.004
N75.1 Abscess of Bartholin's gland	0.000	0.996	0.004
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.996	0.004
M87.2 Osteonecrosis due to previous trauma	0.004	0.996	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.996	0.004
M43.09 Spondylolysis (Site unspecified)	0.000	0.996	0.004
K50.9 Crohn's disease, unspecified	0.000	0.996	0.004
I74 Arterial embolism and thrombosis	0.000	0.996	0.004
I79.1 Aortitis in diseases classified elsewhere	0.000	0.996	0.004
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.996	0.004
X63.0 Home	0.004	0.996	0.000
F32 Depressive episode	0.000	0.996	0.004
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.996	0.004
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.996	0.004
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.004	0.996	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.004	0.996	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.996	0.004
H80.9 Otosclerosis, unspecified	0.004	0.996	0.000
M43.62 Torticollis-Cervical	0.000	0.996	0.004
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.004	0.996	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.004	0.996	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.996	0.004
K75.9 Inflammatory liver disease, unspecified	0.000	0.996	0.004
I09 Other rheumatic heart diseases	0.000	0.996	0.004
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.996	0.004
N75.9 Disease of Bartholin's gland, unspecified	0.000	0.996	0.004
N75.8 Other diseases of Bartholin's gland	0.000	0.996	0.004
M43.69 Torticollis-Site unspe	0.000	0.996	0.004
M43.68 Torticollis-Sacral/sacrococ	0.000	0.996	0.004
M43.67 Torticollis-Lumbosacral	0.000	0.996	0.004
M43.66 Torticollis-Lumbar	0.000	0.996	0.004
M43.65 Torticollis-Thoracolumbar	0.000	0.996	0.004
M43.64 Torticollis-Thoracic	0.000	0.996	0.004
M43.63 Torticollis-Cervicothoracic	0.000	0.996	0.004
M43.61 Torticollis-Occipit-atl-axl	0.000	0.996	0.004
M43.60 Torticollis-Mult site	0.000	0.996	0.004
E78.5 Hyperlipidaemia, unspecified	0.000	0.996	0.004
I07.1 Tricuspid insufficiency	0.000	0.996	0.004
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.996	0.004
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)	0.000	0.996	0.004
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)	0.000	0.996	0.004
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)	0.000	0.996	0.004
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)	0.000	0.996	0.004
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)	0.000	0.996	0.004
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)	0.000	0.996	0.004
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)	0.000	0.996	0.004
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)	0.000	0.996	0.004
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)	0.000	0.996	0.004
M43.49 Other recurrent atlantoaxial subluxation-Site unspe	0.000	0.996	0.004
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ	0.000	0.996	0.004
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral	0.000	0.996	0.004
M43.46 Other recurrent atlantoaxial subluxation-Lumbar	0.000	0.996	0.004
M43.45 Other recurrent atlantoaxial subluxation-Thoracolumbar	0.000	0.996	0.004
M43.44 Other recurrent atlantoaxial subluxation-Thoracic	0.000	0.996	0.004
M43.43 Other recurrent atlantoaxial subluxation-Cervicothoracic	0.000	0.996	0.004
M43.42 Other recurrent atlantoaxial subluxation-Cervical	0.000	0.996	0.004
M43.41 Other recurrent atlantoaxial subluxation-Occipit-atl-axl	0.000	0.996	0.004
M43.40 Other recurrent atlantoaxial subluxation-Mult site	0.000	0.996	0.004
M43.59 Other recurrent vertebral subluxation (Site unspecified)	0.000	0.996	0.004
M43.58 Other recurrent vertebral subluxation (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M43.57 Other recurrent vertebral subluxation (Lumbosacral region)	0.000	0.996	0.004
M43.56 Other recurrent vertebral subluxation (Lumbar region)	0.000	0.996	0.004
M43.55 Other recurrent vertebral subluxation (Thoracolumbar region)	0.000	0.996	0.004
M43.54 Other recurrent vertebral subluxation (Thoracic region)	0.000	0.996	0.004
M43.53 Other recurrent vertebral subluxation (Cervicothoracic region)	0.000	0.996	0.004
M43.52 Other recurrent vertebral subluxation (Cervical region)	0.000	0.996	0.004
M43.51 Other recurrent vertebral subluxation-Occipit-atl-axl	0.000	0.996	0.004
M43.50 Other recurrent vertebral subluxation (Multiple sites in spine)	0.000	0.996	0.004
M43.89 Other specified deforming dorsopathies (Site unspecified)	0.000	0.996	0.004
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M43.87 Other specified deforming dorsopathies (Lumbosacral region)	0.000	0.996	0.004
M43.86 Other specified deforming dorsopathies (Lumbar region)	0.000	0.996	0.004
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)	0.000	0.996	0.004
M43.84 Other specified deforming dorsopathies (Thoracic region)	0.000	0.996	0.004
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)	0.000	0.996	0.004
M43.82 Other specified deforming dorsopathies (Cervical region)	0.000	0.996	0.004
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)	0.000	0.996	0.004
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)	0.000	0.996	0.004
M43.99 Deforming dorsopathy, unspecified (Site unspecified)	0.000	0.996	0.004
M43.98 Deforming dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M43.97 Deforming dorsopathy, unspecified (Lumbosacral region)	0.000	0.996	0.004
M43.96 Deforming dorsopathy, unspecified (Lumbar region)	0.000	0.996	0.004
M43.95 Deforming dorsopathy, unspecified (Thoracolumbar region)	0.000	0.996	0.004
M43.94 Deforming dorsopathy, unspecified (Thoracic region)	0.000	0.996	0.004
M43.93 Deforming dorsopathy, unspecified (Cervicothoracic region)	0.000	0.996	0.004
M43.92 Deforming dorsopathy, unspecified (Cervical region)	0.000	0.996	0.004
M43.91 Deforming dorsopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.996	0.004
M43.90 Deforming dorsopathy, unspecified (Multiple sites in spine)	0.000	0.996	0.004
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.004	0.996	0.000
K50.0 Crohn's disease of small intestine	0.000	0.996	0.004
I71.0 Dissection of aorta [any part]	0.000	0.996	0.004
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.996	0.004
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.996	0.004
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.996	0.004
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.996	0.004
Z03.4 Observation for suspected myocardial infarction	0.000	0.996	0.004
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.996	0.004
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.996	0.004
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.996	0.004
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.996	0.004
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.996	0.004
M87.3 Other secondary osteonecrosis	0.004	0.996	0.000
M87.1 Osteonecrosis due to drugs	0.004	0.996	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.004	0.996	0.000
W29.9 Unspecified place	0.004	0.996	0.000
F32.8 Other depressive episodes	0.000	0.996	0.004
I08 Multiple valve diseases	0.000	0.996	0.004
Y57.5 X-ray contrast media	0.000	0.996	0.004
D07.5 Prostate	0.004	0.996	0.000
I06 Rheumatic aortic valve diseases	0.000	0.996	0.004
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.996	0.004
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.000	0.996	0.003
M43.05 Spondylolysis (Thoracolumbar region)	0.000	0.996	0.003
M43.04 Spondylolysis (Thoracic region)	0.000	0.996	0.003
M43.03 Spondylolysis (Cervicothoracic region)	0.000	0.996	0.003
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.000	0.996	0.003
M43.00 Spondylolysis (Multiple sites in spine)	0.000	0.996	0.003
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.996	0.004
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.003	0.996	0.000
I09.9 Rheumatic heart disease, unspecified	0.000	0.996	0.003
K75.2 Nonspecific reactive hepatitis	0.000	0.996	0.003
K75.1 Phlebitis of portal vein	0.000	0.996	0.003
M43.29 Other fusion of spine (Site unspecified)	0.000	0.996	0.003
M43.28 Other fusion of spine (Sacral and sacrococcygeal region)	0.000	0.996	0.003
M43.25 Other fusion of spine (Thoracolumbar region)	0.000	0.996	0.003
M43.24 Other fusion of spine (Thoracic region)	0.000	0.996	0.003
M43.23 Other fusion of spine (Cervicothoracic region)	0.000	0.996	0.003
M43.22 Other fusion of spine (Cervical region)	0.000	0.996	0.003
M43.21 Other fusion of spine (Occipito-atlanto-axial region)	0.000	0.996	0.003
M43.20 Other fusion of spine (Multiple sites in spine)	0.000	0.996	0.003
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.996	0.003
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.996	0.003
M87.89 Other osteonecrosis (Site unspecified)	0.003	0.996	0.000
M87.88 Other osteonecrosis (Other)	0.003	0.996	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.003	0.996	0.000
M87.86 Other osteonecrosis (Lower leg)	0.003	0.996	0.000
M87.84 Other osteonecrosis (Hand)	0.003	0.996	0.000
M87.83 Other osteonecrosis (Forearm)	0.003	0.996	0.000
M87.82 Other osteonecrosis (Upper arm)	0.003	0.996	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.003	0.996	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.003	0.996	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.997	0.003
I01.8 Other acute rheumatic heart disease	0.000	0.997	0.003
I01.2 Acute rheumatic myocarditis	0.000	0.997	0.003
I01.1 Acute rheumatic endocarditis	0.000	0.997	0.003
I01.0 Acute rheumatic pericarditis	0.000	0.997	0.003
I02.9 Rheumatic chorea without heart involvement	0.000	0.997	0.003
I02.0 Rheumatic chorea with heart involvement	0.000	0.997	0.003
Y52 Agents primarily affecting the cardiovascular system	0.000	0.997	0.003
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.003	0.997	0.000
I95.2 Hypotension due to drugs	0.000	0.997	0.003
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.003	0.997	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.003	0.997	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.003	0.997	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.003	0.997	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.003	0.997	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.003	0.997	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.003	0.997	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.997	0.003
I07.8 Other tricuspid valve diseases	0.000	0.997	0.003
I07.2 Tricuspid stenosis with insufficiency	0.000	0.997	0.003
I07.0 Tricuspid stenosis	0.000	0.997	0.003
K75.0 Abscess of liver	0.000	0.997	0.003
I74.8 Embolism and thrombosis of other arteries	0.000	0.997	0.003
M43.06 Spondylolysis (Lumbar region)	0.000	0.997	0.003
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.997	0.003
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.997	0.003
I74.5 Embolism and thrombosis of iliac artery	0.000	0.997	0.003
D45 Polycythaemia vera	0.003	0.997	0.000
G63.2 Diabetic polyneuropathy	0.003	0.997	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.997	0.003
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.003	0.997	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.003	0.997	0.000
I09.8 Other specified rheumatic heart diseases	0.000	0.997	0.003
I09.2 Chronic rheumatic pericarditis	0.000	0.997	0.003
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.997	0.003
I09.0 Rheumatic myocarditis	0.000	0.997	0.003
M43.07 Spondylolysis (Lumbosacral region)	0.000	0.997	0.003
M43.26 Other fusion of spine (Lumbar region)	0.000	0.997	0.003
F32.0 Mild depressive episode	0.000	0.997	0.003
N89.5 Stricture and atresia of vagina	0.000	0.997	0.003
I78 Diseases of capillaries	0.000	0.997	0.003
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.997	0.003
M43.27 Other fusion of spine (Lumbosacral region)	0.000	0.997	0.003
M90.7 Fracture of bone in neoplastic disease	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.003	0.997	0.000
Z99.1 Dependence on respirator	0.003	0.997	0.000
I28 Other diseases of pulmonary vessels	0.000	0.997	0.003
I85 Oesophageal varices	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.997	0.003
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
S89.9 Unspecified injury of lower leg	0.000	0.997	0.003
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.997	0.003
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.997	0.003
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.003	0.997	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.003	0.997	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.003	0.997	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.003	0.997	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.003	0.997	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.003	0.997	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.003	0.997	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.003	0.997	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.003	0.997	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.003	0.997	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.003	0.997	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.003	0.997	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.003	0.997	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.003	0.997	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.003	0.997	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.003	0.997	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.003	0.997	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.003	0.997	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.003	0.997	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.003	0.997	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.003	0.997	0.000
M87.38 Other secondary osteonecrosis (Other)	0.003	0.997	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.003	0.997	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.003	0.997	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.003	0.997	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.003	0.997	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.003	0.997	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.003	0.997	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.003	0.997	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.003	0.997	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.997	0.003
I95 Hypotension	0.000	0.997	0.003
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.997	0.003
I08.9 Multiple valve disease, unspecified	0.000	0.997	0.003
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
I26 Pulmonary embolism	0.000	0.997	0.003
Z72.2 Drug use	0.000	0.997	0.003
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.997	0.003
T43.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
M40-M43 Deforming dorsopathies	0.000	0.997	0.003
T46.1 Calcium-channel blockers	0.003	0.997	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.997	0.003
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.997	0.003
I06.8 Other rheumatic aortic valve diseases	0.000	0.997	0.003
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.997	0.003
I06.1 Rheumatic aortic insufficiency	0.000	0.997	0.003
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.997	0.003
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.997	0.002
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.003	0.997	0.000
K92.0 Haematemesis	0.003	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
M90 Osteopathies in diseases classified elsewhere	0.003	0.997	0.000
E04.2 Non-toxic multinodular goitre	0.003	0.997	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.997	0.003
Y52.7 Peripheral vasodilators	0.000	0.997	0.003
I95.1 Orthostatic hypotension	0.000	0.997	0.003
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.997	0.003
Y57.8 Other drugs and medicaments	0.000	0.997	0.003
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.997	0.003
M90.78 Fracture of bone in neoplastic disease (Other)	0.003	0.997	0.000
I06.0 Rheumatic aortic stenosis	0.000	0.997	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
I85.0 Oesophageal varices with bleeding	0.003	0.997	0.000
Y60.0 During surgical operation	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
M41 Scoliosis	0.000	0.997	0.003
W29 Contact with other powered hand tools and household machinery	0.003	0.997	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.997	0.003
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.003	0.997	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
T92.1 Sequelae of fracture of arm	0.003	0.997	0.000
X63.9 Unspecified place	0.002	0.997	0.000
X63.8 Other specified place	0.002	0.997	0.000
X63.7 Farm	0.002	0.997	0.000
X63.6 Industrial and construction area	0.002	0.997	0.000
X63.5 Trade and service area	0.002	0.997	0.000
X63.4 Street and highway	0.002	0.997	0.000
X63.3 Sports and athletics area	0.002	0.997	0.000
X63.2 School, other institution and public administrative area	0.002	0.997	0.000
X63.1 Residential institution	0.002	0.997	0.000
I28.8 Other specified diseases of pulmonary vessels	0.000	0.997	0.002
Y57 Other and unspecified drugs and medicaments	0.000	0.997	0.003
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.997	0.002
Z72 Problems related to lifestyle	0.000	0.997	0.003
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.997	0.002
F32.1 Moderate depressive episode	0.000	0.997	0.003
I78.8 Other diseases of capillaries	0.000	0.997	0.002
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.002	0.997	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.002	0.997	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.002	0.997	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.002	0.997	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.997	0.000
I95.0 Idiopathic hypotension	0.000	0.997	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.997	0.002
R61 Hyperhidrosis	0.000	0.997	0.003
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.997	0.000
M86-M90 Other osteopathies	0.003	0.997	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.997	0.002
I28.1 Aneurysm of pulmonary artery	0.000	0.997	0.002
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.997	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.997	0.000
T44.0 Anticholinesterase agents	0.002	0.997	0.000
M41.9 Scoliosis, unspecified	0.000	0.997	0.003
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.997	0.003
T43.6 Psychostimulants with abuse potential	0.002	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.997	0.000
T38.7 Androgens and anabolic congeners	0.002	0.997	0.000
T38.5 Other oestrogens and progestogens	0.002	0.997	0.000
T38.4 Oral contraceptives	0.002	0.997	0.000
T38.2 Antithyroid drugs	0.002	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.997	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
H80 Otosclerosis	0.002	0.998	0.000
I10-I15 Hypertensive diseases	0.000	0.998	0.002
X60-X84 Intentional self-harm	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.000	0.998	0.002
O14.1 Severe preeclampsia	0.000	0.998	0.002
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.998	0.002
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.002	0.998	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations