TreeWAS – Variant ID: rs2176598

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.677	0.323
I51.7 Cardiomegaly	0.000	0.698	0.302
I10-I15 Hypertensive diseases	0.000	0.943	0.057
I11 Hypertensive heart disease	0.000	0.954	0.046
I13 Hypertensive heart and renal disease	0.000	0.960	0.040
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.961	0.039
I15 Secondary hypertension	0.000	0.968	0.032
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.969	0.030
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.971	0.029
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.971	0.029
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.972	0.028
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.973	0.027
I15.2 Hypertension secondary to endocrine disorders	0.000	0.975	0.025
I15.9 Seconday hypertension, unspecified	0.000	0.976	0.024
I15.8 Other secondary hypertension	0.000	0.977	0.023
I15.0 Renovascular hypertension	0.000	0.980	0.020
H36.0 Diabetic retinopathy	0.000	0.983	0.017
I15.1 Hypertension secondary to other renal disorders	0.000	0.985	0.015
R82.9 Other and unspecified abnormal finding in urine	0.015	0.985	0.000
R82 Other abnormal findings in urine	0.013	0.987	0.000
H35.0 Background retinopathy and retinal vascular changes	0.000	0.987	0.013
R82.8 Abnormal findings on cytological and histological examination of urine	0.013	0.987	0.000
R80 Isolated proteinuria	0.013	0.987	0.000
I12 Hypertensive renal disease	0.000	0.988	0.012
H36 Retinal disorders in diseases classified elsewhere	0.000	0.988	0.012
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.012	0.988	0.000
N76.0 Acute vaginitis	0.000	0.989	0.011
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.010	0.990	0.000
R82.3 Haemoglobinuria	0.010	0.990	0.000
R82.2 Biliuria	0.010	0.990	0.000
R82.0 Chyluria	0.010	0.990	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.009	0.990	0.000
R82.4 Acetonuria	0.009	0.990	0.000
Z29.2 Other prophylactic chemotherapy	0.009	0.991	0.000
R82.1 Myoglobinuria	0.009	0.991	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.991	0.009
R81 Glycosuria	0.009	0.991	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.991	0.009
H40.1 Primary open-angle glaucoma	0.000	0.991	0.009
H35 Other retinal disorders	0.000	0.992	0.008
H30-H36 Disorders of choroid and retina	0.000	0.992	0.008
Z22 Carrier of infectious disease	0.008	0.992	0.000
Z29 Need for other prophylactic measures	0.008	0.992	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.992	0.008
Z22.3 Carrier of other specified bacterial diseases	0.008	0.992	0.000
H35.3 Degeneration of macula and posterior pole	0.000	0.992	0.008
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.008	0.992	0.000
Z22.5 Carrier of viral hepatitis	0.008	0.992	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.007	0.993	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.007	0.993	0.000
I22 Subsequent myocardial infarction	0.000	0.993	0.007
H35.6 Retinal haemorrhage	0.000	0.993	0.007
S00.3 Superficial injury of nose	0.007	0.993	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.006	0.993	0.000
H31 Other disorders of choroid	0.000	0.993	0.007
Z29.8 Other specified prophylactic measures	0.007	0.993	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.993	0.006
L05.9 Pilonidal cyst without abscess	0.006	0.994	0.000
H35.2 Other proliferative retinopathy	0.000	0.994	0.006
H35.1 Retinopathy of prematurity	0.000	0.994	0.006
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.994	0.006
Z22.9 Carrier of infectious disease, unspecified	0.006	0.994	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.006	0.994	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.006	0.994	0.000
Z22.2 Carrier of diphtheria	0.006	0.994	0.000
Z22.0 Carrier of typhoid	0.006	0.994	0.000
Z20 Contact with and exposure to communicable diseases	0.006	0.994	0.000
Z29.9 Prophylactic measure, unspecified	0.006	0.994	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.006	0.994	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.006	0.994	0.000
Z22.8 Carrier of other infectious diseases	0.006	0.994	0.000
H34 Retinal vascular occlusions	0.000	0.994	0.006
H31.9 Disorder of choroid, unspecified	0.000	0.994	0.006
Z28 Immunisation not carried out	0.006	0.994	0.000
Z25 Need for immunisation against other single viral diseases	0.006	0.994	0.000
Z23 Need for immunisation against single bacterial diseases	0.006	0.994	0.000
H31.1 Choroidal degeneration	0.000	0.994	0.006
Z27 Need for immunisation against combinations of infectious diseases	0.006	0.994	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.006	0.994	0.000
Z29.0 Isolation	0.006	0.994	0.000
H30 Chorioretinal inflammation	0.000	0.994	0.005
H33.3 Retinal breaks without detachment	0.000	0.995	0.005
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.005	0.995	0.000
Z24 Need for immunisation against certain single viral diseases	0.005	0.995	0.000
Z26 Need for immunisation against other single infectious diseases	0.005	0.995	0.000
N76 Other inflammation of vagina and vulva	0.000	0.995	0.005
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.995	0.005
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
H34.8 Other retinal vascular occlusions	0.000	0.995	0.005
N76.8 Other specified inflammation of vagina and vulva	0.000	0.995	0.005
H31.4 Choroidal detachment	0.000	0.995	0.005
H31.2 Hereditary choroidal dystrophy	0.000	0.995	0.005
H35.7 Separation of retinal layers	0.000	0.995	0.005
H31.0 Chorioretinal scars	0.000	0.995	0.005
H35.5 Hereditary retinal dystrophy	0.000	0.995	0.005
Z20.9 Contact with and exposure to unspecified communicable disease	0.005	0.995	0.000
Z20.1 Contact with and exposure to tuberculosis	0.005	0.995	0.000
H33 Retinal detachments and breaks	0.000	0.995	0.005
H31.3 Choroidal haemorrhage and rupture	0.000	0.995	0.005
D17.9 Benign lipomatous neoplasm, unspecified	0.000	0.995	0.005
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.000	0.995	0.004
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.004
H35.8 Other specified retinal disorders	0.000	0.995	0.005
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.004	0.995	0.000
Z20.6 Contact with and exposure to human immunodeficiency virus [HIV]	0.004	0.995	0.000
Z20.5 Contact with and exposure to viral hepatitis	0.004	0.995	0.000
Z20.4 Contact with and exposure to rubella	0.004	0.995	0.000
Z20.3 Contact with and exposure to rabies	0.004	0.995	0.000
Z20.2 Contact with and exposure to infections with a predominantly sexual mode of transmission	0.004	0.995	0.000
Z20.0 Contact with and exposure to intestinal infectious diseases	0.004	0.995	0.000
Q21.1 Atrial septal defect	0.005	0.995	0.000
N76.3 Subacute and chronic vulvitis	0.000	0.996	0.004
H34.0 Transient retinal artery occlusion	0.000	0.996	0.004
H31.8 Other specified disorders of choroid	0.000	0.996	0.004
Z23.8 Need for immunisation against other single bacterial diseases	0.004	0.996	0.000
Z23.7 Need for immunisation against pertussis alone	0.004	0.996	0.000
Z23.6 Need for immunisation against diphtheria alone	0.004	0.996	0.000
Z23.5 Need for immunisation against tetanus alone	0.004	0.996	0.000
Z23.4 Need for immunisation against tularaemia	0.004	0.996	0.000
Z23.3 Need for immunisation against plague	0.004	0.996	0.000
Z23.2 Need for immunisation against tuberculosis [BCG]	0.004	0.996	0.000
Z23.1 Need for immunisation against typhoid-paratyphoid alone [TAB]	0.004	0.996	0.000
Z23.0 Need for immunisation against cholera alone	0.004	0.996	0.000
Z25.8 Need for immunisation against other specified single viral diseases	0.004	0.996	0.000
Z25.1 Need for immunisation against influenza	0.004	0.996	0.000
Z25.0 Need for immunisation against mumps alone	0.004	0.996	0.000
Z28.9 Immunisation not carried out for unspecified reason	0.004	0.996	0.000
Z28.8 Immunisation not carried out for other reasons	0.004	0.996	0.000
Z28.2 Immunisation not carried out because of patient's decision for other and unspecified reasons	0.004	0.996	0.000
Z28.1 Immunisation not carried out because of patient's decision for reasons of belief or group pressure	0.004	0.996	0.000
Z28.0 Immunisation not carried out because of contraindication	0.004	0.996	0.000
H30.2 Posterior cyclitis	0.000	0.996	0.004
Z27.9 Need for immunisation against unspecified combinations of infectious diseases	0.004	0.996	0.000
Z27.8 Need for immunisation against other combinations of infectious diseases	0.004	0.996	0.000
Z27.3 Need for immunisation against diphtheria-tetanus-pertussis with poliomyelitis [DTP + polio]	0.004	0.996	0.000
Z27.2 Need for immunisation against diphtheria-tetanus-pertussis with typhoid-paratyphoid [DTP + TAB]	0.004	0.996	0.000
Z27.1 Need for immunisation against diphtheria-tetanus-pertussis, combined [DTP]	0.004	0.996	0.000
Z27.0 Need for immunisation against cholera with typhoid-paratyphoid [cholera + TAB]	0.004	0.996	0.000
N76.5 Ulceration of vagina	0.000	0.996	0.004
Z20.8 Contact with and exposure to other communicable diseases	0.004	0.996	0.000
Z27.4 Need for immunisation against measles-mumps-rubella [MMR]	0.004	0.996	0.000
S32.0 Fracture of lumbar vertebra	0.004	0.996	0.000
L05 Pilonidal cyst	0.004	0.996	0.000
H30.8 Other chorioretinal inflammations	0.000	0.996	0.004
H30.1 Disseminated chorioretinal inflammation	0.000	0.996	0.004
H30.0 Focal chorioretinal inflammation	0.000	0.996	0.004
L05.0 Pilonidal cyst with abscess	0.004	0.996	0.000
Z24.6 Need for immunisation against viral hepatitis	0.004	0.996	0.000
Z24.4 Need for immunisation against measles alone	0.004	0.996	0.000
Z24.3 Need for immunisation against yellow fever	0.004	0.996	0.000
Z24.2 Need for immunisation against rabies	0.004	0.996	0.000
Z24.1 Need for immunisation against arthropod-borne viral encephalitis	0.004	0.996	0.000
Z24.0 Need for immunisation against poliomyelitis	0.004	0.996	0.000
Z26.8 Need for immunisation against other specified single infectious diseases	0.004	0.996	0.000
Z26.0 Need for immunisation against leishmaniasis	0.004	0.996	0.000
N92.4 Excessive bleeding in the premenopausal period	0.004	0.996	0.000
H34.1 Central retinal artery occlusion	0.000	0.996	0.004
D23.6 Skin of upper limb, including shoulder	0.000	0.996	0.004
H34.9 Retinal vascular occlusion, unspecified	0.000	0.996	0.004
I51 Complications and ill-defined descriptions of heart disease	0.000	0.996	0.004
J38.1 Polyp of vocal cord and larynx	0.000	0.996	0.004
N76.1 Subacute and chronic vaginitis	0.000	0.996	0.004
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.996	0.004
R01.0 Benign and innocent cardiac murmurs	0.000	0.996	0.004
Z24.5 Need for immunisation against rubella alone	0.004	0.996	0.000
Z26.9 Need for immunisation against unspecified infectious disease	0.003	0.996	0.000
H35.9 Retinal disorder, unspecified	0.000	0.996	0.003
Z29.1 Prophylactic immunotherapy	0.004	0.996	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.996	0.004
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.996	0.004
H34.2 Other retinal artery occlusions	0.000	0.996	0.003
C15.5 Lower third of oesophagus	0.004	0.996	0.000
H30.9 Chorioretinal inflammation, unspecified	0.000	0.996	0.003
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.996	0.003
N76.6 Ulceration of vulva	0.000	0.997	0.003
N94.1 Dyspareunia	0.000	0.997	0.003
R12 Heartburn	0.003	0.997	0.000
S32.01 Fracture of lumbar vertebra (open)	0.003	0.997	0.000
C15.9 Oesophagus, unspecified	0.003	0.997	0.000
N76.2 Acute vulvitis	0.000	0.997	0.003
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.997	0.003
C15 Malignant neoplasm of oesophagus	0.003	0.997	0.000
C15.4 Middle third of oesophagus	0.003	0.997	0.000
I12.9 Hypertensive renal disease without renal failure	0.001	0.997	0.002
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.997	0.003
S32 Fracture of lumbar spine and pelvis	0.003	0.997	0.000
C44.5 Skin of trunk	0.000	0.997	0.003
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.997	0.003
B02.9 Zoster without complication	0.000	0.997	0.003
H33.4 Traction detachment of retina	0.000	0.997	0.003
S32.7 Multiple fractures of lumbar spine and pelvis	0.003	0.997	0.000
Y85.0 Sequelae of motor-vehicle accident	0.000	0.997	0.003
N13 Obstructive and reflux uropathy	0.003	0.997	0.000
F60.3 Emotionally unstable personality disorder	0.003	0.997	0.000
I22.8 Subsequent myocardial infarction of other sites	0.001	0.997	0.002
N13.5 Kinking and stricture of ureter without hydronephrosis	0.003	0.997	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.997	0.003
I51.5 Myocardial degeneration	0.000	0.997	0.003
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.003	0.997	0.000
I51.6 Cardiovascular disease, unspecified	0.000	0.997	0.003
S32.3 Fracture of ilium	0.003	0.997	0.000
N76.4 Abscess of vulva	0.000	0.997	0.003
S30 Superficial injury of abdomen, lower back and pelvis	0.003	0.997	0.000
C15.1 Thoracic part of oesophagus	0.003	0.997	0.000
C15.3 Upper third of oesophagus	0.003	0.997	0.000
N13.6 Pyonephrosis	0.003	0.997	0.000
H33.2 Serous retinal detachment	0.000	0.997	0.003
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.997	0.003
N13.9 Obstructive and reflux uropathy, unspecified	0.003	0.997	0.000
C71.9 Brain, unspecified	0.003	0.997	0.000
C71.8 Overlapping lesion of brain	0.003	0.997	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.997	0.003
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.997	0.003
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.997	0.003
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.997	0.003
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.997	0.003
C15.8 Overlapping lesion of oesophagus	0.003	0.997	0.000
C15.2 Abdominal part of oesophagus	0.003	0.997	0.000
S32.30 Fracture of ilium (closed)	0.003	0.997	0.000
S30.1 Contusion of abdominal wall	0.003	0.997	0.000
S32.2 Fracture of coccyx	0.002	0.997	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.997	0.003
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.002	0.997	0.000
H40 Glaucoma	0.000	0.997	0.003
C15.0 Cervical part of oesophagus	0.002	0.997	0.000
S32.1 Fracture of sacrum	0.002	0.997	0.000
R01 Cardiac murmurs and other cardiac sounds	0.000	0.997	0.003
H35.4 Peripheral retinal degeneration	0.001	0.997	0.002
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.002	0.998	0.000
I51.4 Myocarditis, unspecified	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.000	0.998	0.002
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
I51.0 Cardiac septal defect, acquired	0.000	0.998	0.002
N13.4 Hydroureter	0.002	0.998	0.000
N36.2 Urethral caruncle	0.000	0.998	0.002
H40.4 Glaucoma secondary to eye inflammation	0.000	0.998	0.002
Z83.5 Family history of eye and ear disorders	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.002	0.998	0.000
S32.31 Fracture of ilium (open)	0.002	0.998	0.000
S00.7 Multiple superficial injuries of head	0.000	0.998	0.002
E10.3 With ophthalmic complications	0.000	0.998	0.002
N13.7 Vesicoureteral-reflux-associated uropathy	0.002	0.998	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
M47.9 Spondylosis, unspecified	0.000	0.998	0.002
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.998	0.002
S32.4 Fracture of acetabulum	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.998	0.002
V28.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.998	0.002
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
H33.0 Retinal detachment with retinal break	0.000	0.998	0.002
H40.0 Glaucoma suspect	0.000	0.998	0.002
S32.5 Fracture of pubis	0.002	0.998	0.000
H33.5 Other retinal detachments	0.000	0.998	0.002
J81 Pulmonary oedema	0.000	0.998	0.002
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.998	0.002
N13.8 Other obstructive and reflux uropathy	0.002	0.998	0.000
F60 Specific personality disorders	0.002	0.998	0.000
S32.21 Fracture of coccyx (open)	0.002	0.998	0.000
S32.20 Fracture of coccyx (closed)	0.002	0.998	0.000
E11.3 With ophthalmic complications	0.000	0.998	0.002
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
F60.8 Other specific personality disorders	0.002	0.998	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.002	0.998	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
S32.11 Fracture of sacrum (open)	0.002	0.998	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.002	0.998	0.000
F60.0 Paranoid personality disorder	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
R01.2 Other cardiac sounds	0.000	0.998	0.002
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.002
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
F60.7 Dependent personality disorder	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
Z39.0 Care and examination immediately after delivery	0.002	0.998	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.002	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.002	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
H54.4 Blindness, one eye	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
C71.7 Brain stem	0.002	0.998	0.000
H40.5 Glaucoma secondary to other eye disorders	0.000	0.998	0.002
H40.8 Other glaucoma	0.000	0.998	0.002
H40.3 Glaucoma secondary to eye trauma	0.000	0.998	0.002
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.002	0.998	0.000
S31.1 Open wound of abdominal wall	0.002	0.998	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.000	0.998	0.002
S37 Injury of urinary and pelvic organs	0.002	0.998	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.002	0.998	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
H40.6 Glaucoma secondary to drugs	0.000	0.998	0.002
N05.9 Unspecified	0.002	0.998	0.000
N83.2 Other and unspecified ovarian cysts	0.000	0.998	0.002
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
S30.0 Contusion of lower back and pelvis	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.000	0.998	0.002
C71.1 Frontal lobe	0.002	0.998	0.000
R16.1 Splenomegaly, not elsewhere classified	0.002	0.998	0.000
S32.41 Fracture of acetabulum (open)	0.002	0.998	0.000
S62.31 Fracture of other metacarpal bone (open)	0.000	0.998	0.002
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.002	0.998	0.000
S32.51 Fracture of pubis (open)	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
S34.1 Other injury of lumbar spinal cord	0.002	0.998	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.000	0.998	0.002
Y85 Sequelae of transport accidents	0.000	0.998	0.002
F60.1 Schizoid personality disorder	0.002	0.998	0.000
K04.6 Periapical abscess with sinus	0.000	0.998	0.002
N05.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
C67.4 Posterior wall of bladder	0.002	0.998	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.002	0.998	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.998	0.002
Y85.9 Sequelae of other and unspecified transport accidents	0.000	0.998	0.002
S31 Open wound of abdomen, lower back and pelvis	0.002	0.998	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.998	0.002
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.002	0.998	0.000
F60.4 Histrionic personality disorder	0.002	0.998	0.000
G03.9 Meningitis, unspecified	0.002	0.998	0.000
S37.3 Injury of urethra	0.002	0.998	0.000
C71.2 Temporal lobe	0.002	0.998	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.002	0.998	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.002	0.998	0.000
V28 Motorcycle rider injured in noncollision transport accident	0.000	0.998	0.002
S62.61 Fracture of other finger (open)	0.000	0.998	0.002
I51.9 Heart disease, unspecified	0.000	0.998	0.002
S62.5 Fracture of thumb	0.000	0.998	0.002
S30.2 Contusion of external genital organs	0.001	0.998	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.002	0.998	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.002	0.998	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.002	0.998	0.000
S34.4 Injury of lumbosacral plexus	0.002	0.998	0.000
S34.3 Injury of cauda equina	0.002	0.998	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
G24.5 Blepharospasm	0.000	0.998	0.002
S46.3 Injury of muscle and tendon of triceps	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
C71.4 Occipital lobe	0.002	0.998	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.998	0.002
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.998	0.002
N05.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
V28.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.998	0.002
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.998	0.002
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.001	0.998	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.001	0.998	0.000
S33.4 Traumatic rupture of symphysis pubis	0.001	0.998	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.001	0.998	0.000
S33.1 Dislocation of lumbar vertebra	0.001	0.998	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.001	0.998	0.000
S37.8 Injury of other pelvic organs	0.001	0.998	0.000
S37.7 Injury of multiple pelvic organs	0.001	0.998	0.000
S37.6 Injury of uterus	0.001	0.998	0.000
S37.5 Injury of Fallopian tube	0.001	0.998	0.000
S37.4 Injury of ovary	0.001	0.998	0.000
S37.2 Injury of bladder	0.001	0.998	0.000
S37.1 Injury of ureter	0.001	0.998	0.000
S62.6 Fracture of other finger	0.000	0.998	0.002
S37.30 Injury of urethra (without open wound into cavity)	0.001	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.998	0.002
S37.0 Injury of kidney	0.001	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.002
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.998	0.002
S62 Fracture at wrist and hand level	0.000	0.998	0.002
F60.6 Anxious [avoidant] personality disorder	0.001	0.998	0.000
S33.5 Sprain and strain of lumbar spine	0.001	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.001
S36 Injury of intra-abdominal organs	0.002	0.998	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.998	0.002
K60.3 Anal fistula	0.002	0.998	0.000
S37.9 Injury of unspecified pelvic organ	0.001	0.998	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.001	0.998	0.000
S38.2 Traumatic amputation of external genital organs	0.001	0.998	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.001	0.998	0.000
S38.0 Crushing injury of external genital organs	0.001	0.998	0.000
N05 Unspecified nephritic syndrome	0.002	0.998	0.000
F60.5 Anankastic personality disorder	0.001	0.998	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.001	0.998	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.001	0.998	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.001	0.998	0.000
S35.5 Injury of iliac blood vessels	0.001	0.998	0.000
S35.4 Injury of renal blood vessels	0.001	0.998	0.000
S35.3 Injury of portal or splenic vein	0.001	0.998	0.000
S35.1 Injury of inferior vena cava	0.001	0.998	0.000
S35.0 Injury of abdominal aorta	0.001	0.998	0.000
F03 Unspecified dementia	0.000	0.998	0.002
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.000	0.998	0.002
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.998	0.002
S31.8 Open wound of other and unspecified parts of abdomen	0.001	0.998	0.000
S31.3 Open wound of scrotum and testes	0.001	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.001	0.998	0.000
S31.5 Open wound of other and unspecified external genital organs	0.001	0.998	0.000
S35.2 Injury of coeliac or mesenteric artery	0.001	0.998	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.998	0.001
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.998	0.001
S62.1 Fracture of other carpal bone(s)	0.000	0.998	0.001
V28.5 Passenger injured in traffic accident	0.000	0.998	0.001
F60.2 Dissocial personality disorder	0.001	0.998	0.000
J38.3 Other diseases of vocal cords	0.000	0.998	0.002
S37.31 Injury of urethra (with open wound into cavity)	0.001	0.998	0.000
H21.0 Hyphaema	0.000	0.998	0.002
S62.2 Fracture of first metacarpal bone	0.000	0.998	0.001
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.000	0.998	0.001
V28.4 Driver injured in traffic accident	0.000	0.998	0.001
V28.0 Driver injured in nontraffic accident	0.000	0.998	0.001
V28.1 Passenger injured in nontraffic accident	0.000	0.998	0.001
Z96.0 Presence of urogenital implants	0.002	0.998	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.998	0.001
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.002	0.998	0.000
J02.9 Acute pharyngitis, unspecified	0.002	0.998	0.000
J38.5 Laryngeal spasm	0.000	0.998	0.002
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
S62.51 Fracture of thumb (open)	0.000	0.998	0.001
H17.8 Other corneal scars and opacities	0.000	0.998	0.001
N82.3 Fistula of vagina to large intestine	0.001	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
S36.4 Injury of small intestine	0.001	0.998	0.000
S37.20 Injury of bladder (without open wound into cavity)	0.001	0.998	0.000
O86.0 Infection of obstetric surgical wound	0.000	0.998	0.001
S31.2 Open wound of penis	0.001	0.998	0.000
S62.7 Multiple fractures of fingers	0.000	0.998	0.001
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.999	0.001
S37.01 Injury of kidney (with open wound into cavity)	0.001	0.999	0.000
S37.11 Injury of ureter (with open wound into cavity)	0.001	0.999	0.000
S37.10 Injury of ureter (without open wound into cavity)	0.001	0.999	0.000
S37.21 Injury of bladder (with open wound into cavity)	0.001	0.999	0.000
S37.41 Injury of ovary (with open wound into cavity)	0.001	0.999	0.000
S37.40 Injury of ovary (without open wound into cavity)	0.001	0.999	0.000
S37.51 Injury of fallopian tube (with open wound into cavity)	0.001	0.999	0.000
S37.50 Injury of fallopian tube (without open wound into cavity)	0.001	0.999	0.000
S37.61 Injury of uterus (with open wound into cavity)	0.001	0.999	0.000
S37.60 Injury of uterus (without open wound into cavity)	0.001	0.999	0.000
S37.71 Injury of multiple pelvic organs (with open wound into cavity)	0.001	0.999	0.000
S37.70 Injury of multiple pelvic organs (without open wound into cavity)	0.001	0.999	0.000
S37.81 Injury of other pelvic organs (with open wound into cavity)	0.001	0.999	0.000
S37.80 Injury of other pelvic organs (without open wound into cavity)	0.001	0.999	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.999	0.001
J18.0 Bronchopneumonia, unspecified	0.000	0.999	0.001
K00.6 Disturbances in tooth eruption	0.001	0.999	0.000
V28.3 Person injured while boarding or alighting	0.000	0.999	0.001
Z31 Procreative management	0.001	0.999	0.000
S32.40 Fracture of acetabulum (closed)	0.001	0.999	0.000
N05.8 Other	0.001	0.999	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.999	0.001
S37.00 Injury of kidney (without open wound into cavity)	0.001	0.999	0.000
S37.91 Injury of unspecified pelvic organ (with open wound into cavity)	0.001	0.999	0.000
C67.8 Overlapping lesion of bladder	0.001	0.999	0.000
L60.8 Other nail disorders	0.000	0.999	0.001
N05.6 Dense deposit disease	0.001	0.999	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N05.0 Minor glomerular abnormality	0.001	0.999	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.001	0.999	0.000
S36.7 Injury of multiple intra-abdominal organs	0.001	0.999	0.000
S36.6 Injury of rectum	0.001	0.999	0.000
S36.5 Injury of colon	0.001	0.999	0.000
S36.3 Injury of stomach	0.001	0.999	0.000
S36.2 Injury of pancreas	0.001	0.999	0.000
S62.70 Multiple fractures of fingers (closed)	0.000	0.999	0.001
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.001	0.999	0.000
O70.9 Perineal laceration during delivery, unspecified	0.001	0.999	0.000
Q21.4 Aortopulmonary septal defect	0.001	0.999	0.000
Q21.2 Atrioventricular septal defect	0.001	0.999	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.999	0.001
Z31.4 Procreative investigation and testing	0.000	0.999	0.001
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.001	0.999	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.999	0.001
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.001	0.999	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.001	0.999	0.000
S37.90 Injury of unspecified pelvic organ (without open wound into cavity)	0.001	0.999	0.000
S62.21 Fracture of first metacarpal bone (open)	0.000	0.999	0.001
N05.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
S36.8 Injury of other intra-abdominal organs	0.001	0.999	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.001	0.999	0.000
V28.09 Motorcycle rider injured in noncollision transport accident; driver injured in nontraffic accident; during unspecified activity	0.000	0.999	0.001
V28.49 Motorcycle rider injured in noncollision transport accident; driver injured in traffic accident; during unspecified activity	0.000	0.999	0.001
D61.1 Drug-induced aplastic anaemia	0.001	0.999	0.000
Z31.6 General counselling and advice on procreation	0.001	0.999	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.001	0.999	0.000
E83.5 Disorders of calcium metabolism	0.000	0.999	0.001
I23.8 Other current complications following acute myocardial infarction	0.000	0.999	0.001
N92.5 Other specified irregular menstruation	0.001	0.999	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.999	0.001
H40-H42 Glaucoma	0.000	0.999	0.001
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.999	0.001
S32.50 Fracture of pubis (closed)	0.001	0.999	0.000
S62.60 Fracture of other finger (closed)	0.000	0.999	0.001
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.999	0.001
I60.8 Other subarachnoid haemorrhage	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations