TreeWAS – Variant ID: rs219553

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R40.0 Somnolence	0.036	0.964	0.000
R40 Somnolence, stupor and coma	0.032	0.968	0.000
R40.2 Coma, unspecified	0.032	0.968	0.000
R40.1 Stupor	0.026	0.974	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.021	0.979	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.020	0.980	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.020	0.980	0.000
T40.4 Other synthetic narcotics	0.020	0.980	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.020	0.980	0.000
T40.6 Other and unspecified narcotics	0.020	0.980	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.019	0.981	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.018	0.982	0.000
T42.4 Benzodiazepines	0.018	0.982	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.017	0.983	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.017	0.983	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.017	0.983	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.016	0.984	0.000
T46.1 Calcium-channel blockers	0.016	0.984	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.016	0.984	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.015	0.984	0.000
T36 Poisoning by systemic antibiotics	0.015	0.984	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.015	0.985	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.015	0.985	0.000
T40.8 Lysergide [LSD]	0.015	0.985	0.000
T40.7 Cannabis (derivatives)	0.015	0.985	0.000
T40.5 Cocaine	0.015	0.985	0.000
T40.3 Methadone	0.015	0.985	0.000
T40.1 Heroin	0.015	0.985	0.000
T40.0 Opium	0.015	0.985	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.015	0.985	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.015	0.985	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.015	0.985	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.015	0.985	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.015	0.985	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.015	0.985	0.000
T42.3 Barbiturates	0.015	0.985	0.000
T42.2 Succinimides and oxazolidinediones	0.015	0.985	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.014	0.985	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.014	0.985	0.000
T46.7 Peripheral vasodilators	0.014	0.985	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.014	0.985	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.014	0.985	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.014	0.985	0.000
T40.2 Other opioids	0.014	0.986	0.000
T42.1 Iminostilbenes	0.014	0.986	0.000
T42.0 Hydantoin derivatives	0.014	0.986	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.014	0.986	0.000
C18.2 Ascending colon	0.014	0.986	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.014	0.986	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.014	0.986	0.000
T43.2 Other and unspecified antidepressants	0.014	0.986	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.014	0.986	0.000
T43.6 Psychostimulants with abuse potential	0.013	0.986	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.013	0.987	0.000
C18.6 Descending colon	0.013	0.987	0.000
T50.8 Diagnostic agents	0.013	0.987	0.000
T47.0 Histamine H(2)-receptor antagonists	0.013	0.987	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.013	0.987	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.013	0.987	0.000
C18.5 Splenic flexure	0.013	0.987	0.000
T50.7 Analeptics and opioid receptor antagonists	0.012	0.988	0.000
T50.5 Appetite depressants	0.012	0.988	0.000
T50.4 Drugs affecting uric acid metabolism	0.012	0.988	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.012	0.988	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.012	0.988	0.000
T50.1 Loop [high-ceiling] diuretics	0.012	0.988	0.000
T50.0 Mineralocorticoids and their antagonists	0.012	0.988	0.000
C18 Malignant neoplasm of colon	0.012	0.988	0.000
T43.9 Psychotropic drug, unspecified	0.012	0.988	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.012	0.988	0.000
T36.0 Penicillins	0.012	0.988	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.012	0.988	0.000
T48.5 Anti-common-cold drugs	0.012	0.988	0.000
T48.4 Expectorants	0.012	0.988	0.000
T48.3 Antitussives	0.012	0.988	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.012	0.988	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.012	0.988	0.000
T48.0 Oxytocic drugs	0.012	0.988	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.011	0.988	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.988	0.012
M54.22 Cervicalgia (Cervical region)	0.011	0.989	0.000
T36.9 Systemic antibiotic, unspecified	0.011	0.989	0.000
T36.8 Other systemic antibiotics	0.011	0.989	0.000
T36.7 Antifungal antibiotics, systemically used	0.011	0.989	0.000
T36.6 Rifamycins	0.011	0.989	0.000
T36.5 Aminoglycosides	0.011	0.989	0.000
T36.4 Tetracyclines	0.011	0.989	0.000
T36.3 Macrolides	0.011	0.989	0.000
T36.2 Chloramphenicol group	0.011	0.989	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.011	0.989	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.011	0.989	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.011	0.989	0.000
T47.7 Emetics	0.011	0.989	0.000
T47.6 Antidiarrhoeal drugs	0.011	0.989	0.000
T47.5 Digestants	0.011	0.989	0.000
T47.4 Other laxatives	0.011	0.989	0.000
T47.3 Saline and osmotic laxatives	0.011	0.989	0.000
T47.2 Stimulant laxatives	0.011	0.989	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.011	0.989	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.011	0.989	0.000
T37.5 Antiviral drugs	0.011	0.989	0.000
T37.4 Anthelminthics	0.011	0.989	0.000
T37.3 Other antiprotozoal drugs	0.011	0.989	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.011	0.989	0.000
T37.1 Antimycobacterial drugs	0.011	0.989	0.000
T37.0 Sulphonamides	0.011	0.989	0.000
T41.5 Therapeutic gases	0.011	0.989	0.000
T41.4 Anaesthetic, unspecified	0.011	0.989	0.000
T41.3 Local anaesthetics	0.011	0.989	0.000
T41.2 Other and unspecified general anaesthetics	0.011	0.989	0.000
T41.1 Intravenous anaesthetics	0.011	0.989	0.000
T41.0 Inhaled anaesthetics	0.011	0.989	0.000
T49.9 Topical agent, unspecified	0.011	0.989	0.000
T49.8 Other topical agents	0.011	0.989	0.000
T49.7 Dental drugs, topically applied	0.011	0.989	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.011	0.989	0.000
T49.5 Ophthalmological drugs and preparations	0.011	0.989	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.011	0.989	0.000
T49.3 Emollients, demulcents and protectants	0.011	0.989	0.000
T49.2 Local astringents and local detergents	0.011	0.989	0.000
T49.1 Antipruritics	0.011	0.989	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.011	0.989	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.989	0.011
R45.1 Restlessness and agitation	0.011	0.989	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.010	0.990	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.010	0.990	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.010	0.990	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.010	0.990	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.010	0.990	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.010	0.990	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.010	0.990	0.000
T44.0 Anticholinesterase agents	0.010	0.990	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.010	0.990	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.010	0.990	0.000
C80.9 Malignant neoplasm, unspecified	0.010	0.990	0.000
T45.0 Antiallergic and antiemetic drugs	0.010	0.990	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.010	0.990	0.000
C18.9 Colon, unspecified	0.010	0.990	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.009	0.990	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.009	0.990	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.009	0.991	0.000
T45.8 Other primarily systemic and haematological agents	0.009	0.991	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.009	0.991	0.000
T45.6 Fibrinolysis-affecting drugs	0.009	0.991	0.000
T45.4 Iron and its compounds	0.009	0.991	0.000
T45.3 Enzymes, not elsewhere classified	0.009	0.991	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.009	0.991	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.009	0.991	0.000
T45.5 Anticoagulants	0.009	0.991	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.009	0.991	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.009	0.991	0.000
C18.4 Transverse colon	0.009	0.991	0.000
C79 Secondary malignant neoplasm of other sites	0.009	0.991	0.000
C80 Malignant neoplasm without specification of site	0.009	0.991	0.000
R45 Symptoms and signs involving emotional state	0.009	0.991	0.000
T45.2 Vitamins, not elsewhere classified	0.009	0.991	0.000
C18.3 Hepatic flexure	0.009	0.991	0.000
C77.0 Lymph nodes of head, face and neck	0.009	0.991	0.000
L90.5 Scar conditions and fibrosis of skin	0.009	0.991	0.000
C18.1 Appendix	0.009	0.991	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.009	0.991	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.009	0.991	0.000
T38.9 Other and unspecified hormone antagonists	0.008	0.991	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.008	0.991	0.000
T38.7 Androgens and anabolic congeners	0.008	0.991	0.000
T38.5 Other oestrogens and progestogens	0.008	0.991	0.000
T38.4 Oral contraceptives	0.008	0.991	0.000
T38.2 Antithyroid drugs	0.008	0.991	0.000
T38.0 Glucocorticoids and synthetic analogues	0.008	0.991	0.000
C43 Malignant melanoma of skin	0.009	0.991	0.000
T38.1 Thyroid hormones and substitutes	0.008	0.991	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.009	0.991	0.000
C18.8 Overlapping lesion of colon	0.008	0.991	0.000
C79.2 Secondary malignant neoplasm of skin	0.009	0.991	0.000
C44.0 Skin of lip	0.008	0.992	0.000
G30.9 Alzheimer's disease, unspecified	0.008	0.992	0.000
C18.0 Caecum	0.008	0.992	0.000
C77.4 Inguinal and lower limb lymph nodes	0.008	0.992	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.008	0.992	0.000
R45.5 Hostility	0.008	0.992	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.992	0.008
C77.8 Lymph nodes of multiple regions	0.008	0.992	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.008	0.992	0.000
C43.9 Malignant melanoma of skin, unspecified	0.007	0.992	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.007	0.993	0.000
C79.6 Secondary malignant neoplasm of ovary	0.007	0.993	0.000
C78.0 Secondary malignant neoplasm of lung	0.007	0.993	0.000
C77.1 Intrathoracic lymph nodes	0.007	0.993	0.000
R43 Disturbances of smell and taste	0.007	0.993	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.007	0.993	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.007	0.993	0.000
R45.2 Unhappiness	0.007	0.993	0.000
H02.0 Entropion and trichiasis of eyelid	0.007	0.993	0.000
R45.7 State of emotional shock and stress, unspecified	0.007	0.993	0.000
R45.6 Physical violence	0.007	0.993	0.000
R45.3 Demoralisation and apathy	0.007	0.993	0.000
R46 Symptoms and signs involving appearance and behaviour	0.007	0.993	0.000
S72.0 Fracture of neck of femur	0.000	0.993	0.007
C77.9 Lymph node, unspecified	0.007	0.993	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.007	0.993	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.006	0.993	0.000
R45.4 Irritability and anger	0.007	0.993	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.007	0.993	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.007	0.993	0.000
C43.8 Overlapping malignant melanoma of skin	0.006	0.993	0.000
C43.0 Malignant melanoma of lip	0.006	0.993	0.000
R45.0 Nervousness	0.006	0.993	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.006	0.994	0.000
C43.5 Malignant melanoma of trunk	0.006	0.994	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.006	0.994	0.000
G30 Alzheimer's disease	0.006	0.994	0.000
C77.2 Intra-abdominal lymph nodes	0.006	0.994	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.006	0.994	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.006	0.994	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.006	0.994	0.000
T39.4 Antirheumatics, not elsewhere classified	0.006	0.994	0.000
T39.2 Pyrazolone derivatives	0.006	0.994	0.000
E10.1 With ketoacidosis	0.000	0.994	0.006
R46.2 Strange and inexplicable behaviour	0.006	0.994	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.006	0.994	0.000
M54.2 Cervicalgia	0.006	0.994	0.000
R43.1 Parosmia	0.005	0.994	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.005	0.994	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.005	0.994	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.005	0.994	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.000	0.995	0.005
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.005	0.995	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.005	0.995	0.000
R43.0 Anosmia	0.005	0.995	0.000
R43.2 Parageusia	0.005	0.995	0.000
C76.0 Head, face and neck	0.005	0.995	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.005	0.995	0.000
K86.1 Other chronic pancreatitis	0.000	0.995	0.005
W10.8 Other specified place	0.000	0.995	0.005
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.995	0.005
T39.0 Salicylates	0.005	0.995	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.005	0.995	0.000
C76.1 Thorax	0.005	0.995	0.000
G30.0 Alzheimer's disease with early onset	0.005	0.995	0.000
U80.1 Methicillin resistant agent	0.000	0.995	0.005
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.005	0.995	0.000
R46.6 Undue concern and preoccupation with stressful events	0.005	0.995	0.000
R46.5 Suspiciousness and marked evasiveness	0.005	0.995	0.000
R46.3 Overactivity	0.005	0.995	0.000
R46.1 Bizarre personal appearance	0.005	0.995	0.000
R46.0 Very low level of personal hygiene	0.005	0.995	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.995	0.005
C79.7 Secondary malignant neoplasm of adrenal gland	0.005	0.995	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.005	0.995	0.000
C76.7 Other ill-defined sites	0.005	0.995	0.000
C76.5 Lower limb	0.005	0.995	0.000
C76.4 Upper limb	0.005	0.995	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.995	0.005
G30.1 Alzheimer's disease with late onset	0.005	0.995	0.000
D48.5 Skin	0.005	0.995	0.000
C76.3 Pelvis	0.005	0.995	0.000
C76.2 Abdomen	0.005	0.995	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.995	0.005
R46.4 Slowness and poor responsiveness	0.005	0.995	0.000
C78.2 Secondary malignant neoplasm of pleura	0.005	0.995	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.995	0.001
K86 Other diseases of pancreas	0.000	0.995	0.005
G30.8 Other Alzheimer's disease	0.004	0.995	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.004	0.995	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.004	0.995	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.004	0.995	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.004	0.996	0.000
L72.0 Epidermal cyst	0.004	0.996	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.996	0.004
M54.28 Cervicalgia-Sacral/sacrococ	0.004	0.996	0.000
M54.27 Cervicalgia-Lumbosacral	0.004	0.996	0.000
M54.26 Cervicalgia-Lumbar	0.004	0.996	0.000
M54.25 Cervicalgia-Thoracolumbar	0.004	0.996	0.000
M54.24 Cervicalgia-Thoracic	0.004	0.996	0.000
M54.20 Cervicalgia-Mult site	0.004	0.996	0.000
C77.5 Intrapelvic lymph nodes	0.004	0.996	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.004	0.996	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.996	0.004
D06.9 Cervix, unspecified	0.000	0.996	0.004
E10.5 With peripheral circulatory complications	0.000	0.996	0.004
K86.3 Pseudocyst of pancreas	0.000	0.996	0.004
C43.4 Malignant melanoma of scalp and neck	0.004	0.996	0.000
M54.29 Cervicalgia-Site unspe	0.004	0.996	0.000
S72.2 Subtrochanteric fracture	0.000	0.996	0.004
D48.1 Connective and other soft tissue	0.004	0.996	0.000
F00 Dementia in Alzheimer's disease	0.004	0.996	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.996	0.004
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.004	0.996	0.000
K86.8 Other specified diseases of pancreas	0.000	0.996	0.004
S72 Fracture of femur	0.000	0.996	0.004
D03 Melanoma in situ	0.004	0.996	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.996	0.004
K86.2 Cyst of pancreas	0.000	0.996	0.004
R32 Unspecified urinary incontinence	0.004	0.996	0.000
L29.9 Pruritus, unspecified	0.000	0.996	0.004
R45.8 Other symptoms and signs involving emotional state	0.003	0.996	0.000
D48.0 Bone and articular cartilage	0.004	0.996	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.003	0.996	0.000
L90 Atrophic disorders of skin	0.003	0.996	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.003	0.997	0.000
C77.3 Axillary and upper limb lymph nodes	0.003	0.997	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.003	0.997	0.000
I84.1 Internal haemorrhoids with other complications	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.003	0.997	0.000
E10.3 With ophthalmic complications	0.000	0.997	0.003
D48.4 Peritoneum	0.003	0.997	0.000
D48.3 Retroperitoneum	0.003	0.997	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.003	0.997	0.000
W13.9 Unspecified place	0.000	0.997	0.003
S72.21 Subtrochanteric fracture (open)	0.000	0.997	0.003
D03.6 Melanoma in situ of upper limb, including shoulder	0.003	0.997	0.000
D03.5 Melanoma in situ of trunk	0.003	0.997	0.000
E10.8 With unspecified complications	0.000	0.997	0.003
E10.6 With other specified complications	0.000	0.997	0.003
D48.7 Other specified sites	0.003	0.997	0.000
E10.4 With neurological complications	0.000	0.997	0.003
D03.3 Melanoma in situ of other and unspecified parts of face	0.003	0.997	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.003	0.997	0.000
G30-G32 Other degenerative diseases of the nervous system	0.003	0.997	0.000
E10.7 With multiple complications	0.000	0.997	0.003
C62.9 Testis, unspecified	0.003	0.997	0.000
R52.1 Chronic intractable pain	0.003	0.997	0.000
S72.8 Fractures of other parts of femur	0.000	0.997	0.003
S72.7 Multiple fractures of femur	0.000	0.997	0.003
K86.9 Disease of pancreas, unspecified	0.000	0.997	0.003
D03.9 Melanoma in situ, unspecified	0.003	0.997	0.000
D03.8 Melanoma in situ of other sites	0.003	0.997	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.003	0.997	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.003	0.997	0.000
D03.0 Melanoma in situ of lip	0.003	0.997	0.000
D03.4 Melanoma in situ of scalp and neck	0.003	0.997	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
E10.0 With coma	0.000	0.997	0.003
C44 Other malignant neoplasms of skin	0.003	0.997	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.003	0.997	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.003	0.997	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.997	0.003
C44.9 Malignant neoplasm of skin, unspecified	0.003	0.997	0.000
L90.9 Atrophic disorder of skin, unspecified	0.003	0.997	0.000
L90.8 Other atrophic disorders of skin	0.003	0.997	0.000
L90.6 Striae atrophicae	0.003	0.997	0.000
L90.4 Acrodermatitis chronica atrophicans	0.003	0.997	0.000
L90.3 Atrophoderma of Pasini and Pierini	0.003	0.997	0.000
L90.2 Anetoderma of Jadassohn-Pellizzari	0.003	0.997	0.000
L90.1 Anetoderma of Schweninger-Buzzi	0.003	0.997	0.000
N62 Hypertrophy of breast	0.000	0.997	0.003
W10 Fall on and from stairs and steps	0.000	0.997	0.003
S72.9 Fracture of femur, part unspecified	0.000	0.997	0.003
S72.4 Fracture of lower end of femur	0.000	0.997	0.003
C69.9 Eye, unspecified	0.003	0.997	0.000
M25.83 Other specified joint disorders (Forearm)	0.000	0.997	0.003
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.003	0.997	0.000
C25.2 Tail of pancreas	0.003	0.997	0.000
H26.0 Infantile, juvenile and presenile cataract	0.003	0.997	0.000
M25.8 Other specified joint disorders	0.000	0.997	0.003
C15.9 Oesophagus, unspecified	0.003	0.997	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.002	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.003	0.997	0.000
M25.86 Other specified joint disorders (Lower leg)	0.000	0.997	0.003
M25.84 Other specified joint disorders (Hand)	0.000	0.997	0.003
S82.40 Fracture of fibula alone (closed)	0.000	0.997	0.003
D37-D48 Neoplasms of uncertain or unknown behaviour	0.003	0.997	0.000
I95.1 Orthostatic hypotension	0.003	0.997	0.000
R44.2 Other hallucinations	0.002	0.997	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.997	0.002
C44.3 Skin of other and unspecified parts of face	0.003	0.997	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.003	0.997	0.000
L90.0 Lichen sclerosus et atrophicus	0.002	0.998	0.000
S72.3 Fracture of shaft of femur	0.000	0.998	0.002
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
K05.3 Chronic periodontitis	0.000	0.998	0.002
E10.2 With renal complications	0.000	0.998	0.002
C62 Malignant neoplasm of testis	0.002	0.998	0.000
S72.71 Multiple fractures of femur (open)	0.000	0.998	0.002
S72.70 Multiple fractures of femur (closed)	0.000	0.998	0.002
S72.81 Fractures of other parts of femur (open)	0.000	0.998	0.002
S72.80 Fractures of other parts of femur (closed)	0.000	0.998	0.002
C15.5 Lower third of oesophagus	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
G31.0 Circumscribed brain atrophy	0.002	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.002	0.998	0.000
C15 Malignant neoplasm of oesophagus	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
C44.8 Overlapping lesion of skin	0.002	0.998	0.000
C62.1 Descended testis	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.002	0.998	0.000
C69.0 Conjunctiva	0.002	0.998	0.000
W10.9 Unspecified place	0.000	0.998	0.002
W10.5 Trade and service area	0.000	0.998	0.002
W10.2 School, other institution and public administrative area	0.000	0.998	0.002
W10.0 Home	0.000	0.998	0.002
W10.7 Farm	0.000	0.998	0.002
W10.6 Industrial and construction area	0.000	0.998	0.002
W10.3 Sports and athletics area	0.000	0.998	0.002
W10.1 Residential institution	0.000	0.998	0.002
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.002	0.998	0.000
S72.41 Fracture of lower end of femur (open)	0.000	0.998	0.002
R41.1 Anterograde amnesia	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.002	0.998	0.000
S72.91 Fracture of femur, part unspecified (open)	0.000	0.998	0.002
A41.5 Septicaemia due to other Gram-negative organisms	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
D40.0 Prostate	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.002	0.998	0.000
R41.2 Retrograde amnesia	0.002	0.998	0.000
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
W10.4 Street and highway	0.000	0.998	0.002
D43.0 Brain, supratentorial	0.002	0.998	0.000
D06 Carcinoma in situ of cervix uteri	0.001	0.998	0.001
C18.7 Sigmoid colon	0.002	0.998	0.000
C25 Malignant neoplasm of pancreas	0.002	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
S72.1 Pertrochanteric fracture	0.000	0.998	0.002
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.002	0.998	0.000
C15-C26 Malignant neoplasms of digestive organs	0.002	0.998	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.002	0.998	0.000
H20.1 Chronic iridocyclitis	0.002	0.998	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.998	0.002
M25.82 Other specified joint disorders (Upper arm)	0.000	0.998	0.002
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.998	0.002
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
N80.3 Endometriosis of pelvic peritoneum	0.000	0.998	0.002
S32.7 Multiple fractures of lumbar spine and pelvis	0.002	0.998	0.000
H20 Iridocyclitis	0.002	0.998	0.000
C69.8 Overlapping lesion of eye and adnexa	0.002	0.998	0.000
C69.6 Orbit	0.002	0.998	0.000
C69.5 Lachrymal gland and duct	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
C69.3 Choroid	0.002	0.998	0.000
C69.2 Retina	0.002	0.998	0.000
C69.1 Cornea	0.002	0.998	0.000
N80.2 Endometriosis of Fallopian tube	0.002	0.998	0.000
C70 Malignant neoplasm of meninges	0.002	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.002	0.998	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.002	0.998	0.000
X62.9 Unspecified place	0.002	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.002	0.998	0.000
S72.31 Fracture of shaft of femur (open)	0.000	0.998	0.002
C26 Malignant neoplasm of other and ill-defined digestive organs	0.002	0.998	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.998	0.002
A41.1 Septicaemia due to other specified staphylococcus	0.002	0.998	0.000
C62.0 Undescended testis	0.002	0.998	0.000
D39.1 Ovary	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.002	0.998	0.000
C25.9 Pancreas, unspecified	0.002	0.998	0.000
D46.2 Refractory anaemia with excess of blasts	0.002	0.998	0.000
K55.0 Acute vascular disorders of intestine	0.002	0.998	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.002	0.998	0.000
D46.7 Other myelodysplastic syndromes	0.002	0.998	0.000
C70.0 Cerebral meninges	0.002	0.998	0.000
D40.9 Male genital organ, unspecified	0.002	0.998	0.000
D40.7 Other male genital organs	0.002	0.998	0.000
D48.6 Breast	0.002	0.998	0.000
C15.8 Overlapping lesion of oesophagus	0.002	0.998	0.000
C15.2 Abdominal part of oesophagus	0.002	0.998	0.000
C15.1 Thoracic part of oesophagus	0.002	0.998	0.000
C15.0 Cervical part of oesophagus	0.002	0.998	0.000
C71.9 Brain, unspecified	0.002	0.998	0.000
D40.1 Testis	0.002	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.998	0.002
C26.9 Ill-defined sites within the digestive system	0.002	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.002	0.998	0.000
R44.0 Auditory hallucinations	0.002	0.998	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.002	0.998	0.000
Chapter II Neoplasms	0.002	0.998	0.000
W10.08 Fall on and from stairs and steps; Home; While engaged in other specified activities	0.000	0.998	0.002
W10.04 Fall on and from stairs and steps; Home; While resting, sleeping, eating or engaging in other vital activities	0.000	0.998	0.002
W10.03 Fall on and from stairs and steps; Home; While engaged in other types of work	0.000	0.998	0.002
W10.29 Fall on and from stairs and steps; School, other institution and public administrative area; During unspecified activity	0.000	0.998	0.002
W10.59 Fall on and from stairs and steps; Trade and service area; During unspecified activity	0.000	0.998	0.002
W10.92 Fall on and from stairs and steps; Unspecified place; While working for income	0.000	0.998	0.002
W10.90 Fall on and from stairs and steps; Unspecified place; While engaged in sports activity	0.000	0.998	0.002
D43.9 Central nervous system, unspecified	0.002	0.998	0.000
D43.7 Other parts of central nervous system	0.002	0.998	0.000
D43.3 Cranial nerves	0.002	0.998	0.000
D43.1 Brain, infratentorial	0.002	0.998	0.000
S71.1 Open wound of thigh	0.000	0.998	0.002
S73.0 Dislocation of hip	0.000	0.998	0.002
C15.3 Upper third of oesophagus	0.002	0.998	0.000
C78.7 Secondary malignant neoplasm of liver	0.002	0.998	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.002	0.998	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.998	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.002	0.998	0.000
D46.1 Refractory anaemia with sideroblasts	0.002	0.998	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.002	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.998	0.002
C25.3 Pancreatic duct	0.002	0.998	0.000
W13 Fall from, out of or through building or structure	0.000	0.998	0.002
D06.7 Other parts of cervix	0.001	0.998	0.001
D06.1 Exocervix	0.001	0.998	0.001
H20.8 Other iridocyclitis	0.002	0.998	0.000
R06.8 Other and unspecified abnormalities of breathing	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations