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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2206040
log Bayes Factor = 54.9841
Chromosome 6   position 29,178,514  (GRCh37) Explore rs2206040 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.009 0.991
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.039 0.961
E10.2 With renal complications
0.000 0.044 0.956
E10.1 With ketoacidosis
0.000 0.108 0.892
E10.4 With neurological complications
0.000 0.116 0.884
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.190 0.810
E05.8 Other thyrotoxicosis
0.000 0.196 0.804
E16.1 Other hypoglycaemia
0.000 0.203 0.797
E13 Other specified diabetes mellitus
0.000 0.227 0.773
E10.7 With multiple complications
0.000 0.246 0.754
E14 Unspecified diabetes mellitus
0.000 0.262 0.738
E40-E46 Malnutrition
0.000 0.274 0.726
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E10.0 With coma
0.000 0.288 0.712
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.671 0.329 0.000
E10.6 With other specified complications
0.000 0.343 0.657
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.357 0.642
E10.5 With peripheral circulatory complications
0.000 0.358 0.642
E07 Other disorders of thyroid
0.000 0.358 0.642
E14.3 With ophthalmic complications
0.000 0.360 0.640
E06 Thyroiditis
0.000 0.362 0.638
E13.9 Without complications
0.000 0.380 0.620
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.412 0.588
E14.1 With ketoacidosis
0.000 0.415 0.585
E14.6 With other specified complications
0.000 0.432 0.568
E14.8 With unspecified complications
0.000 0.436 0.564
E10.8 With unspecified complications
0.000 0.439 0.561
E14.4 With neurological complications
0.000 0.441 0.559
E13.8 With unspecified complications
0.000 0.446 0.554
E13.7 With multiple complications
0.000 0.446 0.554
E13.6 With other specified complications
0.000 0.446 0.554
E13.5 With peripheral circulatory complications
0.000 0.446 0.554
E13.4 With neurological complications
0.000 0.446 0.554
E13.2 With renal complications
0.000 0.446 0.554
E13.1 With ketoacidosis
0.000 0.446 0.554
E13.0 With coma
0.000 0.446 0.554
E13.3 With ophthalmic complications
0.000 0.459 0.541
E06.9 Thyroiditis, unspecified
0.000 0.469 0.530
E46 Unspecified protein-energy malnutrition
0.000 0.470 0.530
E14.7 With multiple complications
0.000 0.471 0.529
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.480 0.520
E45 Retarded development following protein-energy malnutrition
0.000 0.480 0.520
E43 Unspecified severe protein-energy malnutrition
0.000 0.480 0.520
E42 Marasmic kwashiorkor
0.000 0.480 0.520
E41 Nutritional marasmus
0.000 0.480 0.520
E40 Kwashiorkor
0.000 0.480 0.520
E12.9 Without complications
0.000 0.486 0.513
E12.8 With unspecified complications
0.000 0.486 0.513
E12.7 With multiple complications
0.000 0.486 0.513
E12.6 With other specified complications
0.000 0.486 0.513
E12.5 With peripheral circulatory complications
0.000 0.486 0.513
E12.4 With neurological complications
0.000 0.486 0.513
E12.3 With ophthalmic complications
0.000 0.486 0.513
E12.2 With renal complications
0.000 0.486 0.513
E12.1 With ketoacidosis
0.000 0.486 0.513
E12.0 With coma
0.000 0.486 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E03 Other hypothyroidism
0.000 0.492 0.508
E07.8 Other specified disorders of thyroid
0.000 0.492 0.508
E14.5 With peripheral circulatory complications
0.000 0.493 0.507
E14.0 With coma
0.000 0.502 0.498
E14.2 Withrenal complications
0.000 0.510 0.490
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.516 0.484
E06.1 Subacute thyroiditis
0.000 0.517 0.482
E07.1 Dyshormogenetic goitre
0.000 0.540 0.460
E07.0 Hypersecretion of calcitonin
0.000 0.540 0.460
E06.4 Drug-induced thyroiditis
0.000 0.542 0.457
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.542 0.457
E06.0 Acute thyroiditis
0.000 0.542 0.457
K90 Intestinal malabsorption
0.000 0.547 0.453
E06.5 Other chronic thyroiditis
0.000 0.557 0.443
R31 Unspecified haematuria
0.418 0.582 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.617 0.383
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.625 0.375
E44.1 Mild protein-energy malnutrition
0.000 0.627 0.373
E44.0 Moderate protein-energy malnutrition
0.000 0.627 0.373
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.628 0.372
E03.5 Myxoedema coma
0.000 0.635 0.365
E03.4 Atrophy of thyroid (acquired)
0.000 0.635 0.365
E03.3 Postinfectious hypothyroidism
0.000 0.635 0.365
E03.1 Congenital hypothyroidism without goitre
0.000 0.645 0.355
E65-E68 Obesity and other hyperalimentation
0.000 0.657 0.343
K90.3 Pancreatic steatorrhoea
0.000 0.675 0.325
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.675 0.325
K90.1 Tropical sprue
0.000 0.675 0.325
K90.8 Other intestinal malabsorption
0.000 0.683 0.317
E03.8 Other specified hypothyroidism
0.000 0.698 0.302
E50-E64 Other nutritional deficiencies
0.000 0.702 0.298
E07.9 Disorder of thyroid, unspecified
0.000 0.704 0.296
K90.9 Intestinal malabsorption, unspecified
0.000 0.722 0.278
E20-E35 Disorders of other endocrine glands
0.000 0.751 0.249
E67 Other hyperalimentation
0.000 0.754 0.246
E68 Sequelae of hyperalimentation
0.000 0.754 0.246
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.767 0.233
E24 Cushing's syndrome
0.000 0.769 0.231
E21.3 Hyperparathyroidism, unspecified
0.000 0.773 0.227
E03.9 Hypothyroidism, unspecified
0.000 0.774 0.226
E51 Thiamine deficiency
0.000 0.786 0.214
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.786 0.213
E50 Vitamin A deficiency
0.000 0.786 0.213
E60 Dietary zinc deficiency
0.000 0.786 0.213
E59 Dietary selenium deficiency
0.000 0.786 0.213
E52 Niacin deficiency [pellagra]
0.000 0.786 0.213
E54 Ascorbic acid deficiency
0.000 0.790 0.210
E56 Other vitamin deficiencies
0.000 0.797 0.203
E65 Localised adiposity
0.000 0.800 0.200
E24.9 Cushing's syndrome, unspecified
0.000 0.800 0.200
E58 Dietary calcium deficiency
0.000 0.803 0.197
E11 Non-insulin-dependent diabetes mellitus
0.000 0.803 0.197
E24.0 Pituitary-dependent Cushing's disease
0.000 0.806 0.194
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.806 0.194
E63 Other nutritional deficiencies
0.000 0.806 0.193
E24.2 Drug-induced Cushing's syndrome
0.000 0.817 0.183
E21.4 Other specified disorders of parathyroid gland
0.000 0.818 0.182
E11.6 With other specified complications
0.000 0.819 0.181
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.821 0.179
E32 Diseases of thymus
0.000 0.821 0.179
E30 Disorders of puberty, not elsewhere classified
0.000 0.821 0.179
E55 Vitamin D deficiency
0.000 0.822 0.178
E67.8 Other specified hyperalimentation
0.000 0.823 0.177
E67.3 Hypervitaminosis D
0.000 0.823 0.177
E67.2 Megavitamin-B6 syndrome
0.000 0.823 0.177
E67.1 Hypercarotenaemia
0.000 0.823 0.177
E67.0 Hypervitaminosis A
0.000 0.823 0.177
E20 Hypoparathyroidism
0.000 0.823 0.177
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.824 0.176
E25 Adrenogenital disorders
0.000 0.826 0.174
E61 Deficiency of other nutrient elements
0.000 0.826 0.174
E83 Disorders of mineral metabolism
0.170 0.827 0.003
E06.3 Autoimmune thyroiditis
0.000 0.828 0.171
E31 Polyglandular dysfunction
0.000 0.828 0.171
E21.2 Other hyperparathyroidism
0.000 0.831 0.169
E24.8 Other Cushing's syndrome
0.000 0.834 0.166
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.834 0.166
E24.3 Ectopic ACTH syndrome
0.000 0.834 0.166
E24.1 Nelson's syndrome
0.000 0.834 0.166
E53 Deficiency of other B group vitamins
0.000 0.841 0.159
E11.2 With renal complications
0.000 0.844 0.156
E51.2 Wernicke's encephalopathy
0.000 0.846 0.154
E51.9 Thiamine deficiency, unspecified
0.000 0.846 0.153
E51.8 Other manifestations of thiamine deficiency
0.000 0.846 0.153
E51.1 Beriberi
0.000 0.846 0.153
E50.9 Vitamin A deficiency, unspecified
0.000 0.847 0.153
E50.8 Other manifestations of vitamin A deficiency
0.000 0.847 0.153
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.847 0.153
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.847 0.153
E50.5 Vitamin A deficiency with night blindness
0.000 0.847 0.153
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.847 0.153
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.847 0.153
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.847 0.153
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.847 0.153
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.847 0.153
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.847 0.153
E64.8 Sequelae of other nutritional deficiencies
0.000 0.847 0.153
E64.3 Sequelae of rickets
0.000 0.847 0.153
E64.2 Sequelae of vitamin C deficiency
0.000 0.847 0.153
E64.1 Sequelae of vitamin A deficiency
0.000 0.847 0.153
E64.0 Sequelae of protein-energy malnutrition
0.000 0.847 0.153
E29 Testicular dysfunction
0.000 0.849 0.151
E11.0 With coma
0.000 0.849 0.151
E83.3 Disorders of phosphorus metabolism
0.148 0.851 0.001
E56.9 Vitamin deficiency, unspecified
0.000 0.854 0.146
E56.8 Deficiency of other vitamins
0.000 0.854 0.146
E56.0 Deficiency of vitamin E
0.000 0.854 0.146
E11.1 With ketoacidosis
0.000 0.858 0.142
E11.7 With multiple complications
0.000 0.859 0.141
E28 Ovarian dysfunction
0.000 0.859 0.141
E63.8 Other specified nutritional deficiencies
0.000 0.861 0.139
E63.1 Imbalance of constituents of food intake
0.000 0.861 0.139
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.861 0.139
E34 Other endocrine disorders
0.000 0.861 0.138
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.861 0.138
C20 Malignant neoplasm of rectum
0.000 0.862 0.138
C15-C26 Malignant neoplasms of digestive organs
0.000 0.864 0.136
E56.1 Deficiency of vitamin K
0.000 0.865 0.135
M45.X9 Ankylosing spondylitis (Site unspecified)
0.134 0.866 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.871 0.128
E30.8 Other disorders of puberty
0.000 0.871 0.128
E30.1 Precocious puberty
0.000 0.871 0.128
E30.0 Delayed puberty
0.000 0.871 0.128
E32.9 Disease of thymus, unspecified
0.000 0.871 0.128
E32.8 Other diseases of thymus
0.000 0.871 0.128
E32.1 Abscess of thymus
0.000 0.871 0.128
E32.0 Persistent hyperplasia of thymus
0.000 0.871 0.128
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.871 0.128
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.871 0.128
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.871 0.128
E55.0 Rickets, active
0.000 0.872 0.128
E20.8 Other hypoparathyroidism
0.000 0.873 0.127
E20.1 Pseudohypoparathyroidism
0.000 0.873 0.127
E20.0 Idiopathic hypoparathyroidism
0.000 0.873 0.127
C15 Malignant neoplasm of oesophagus
0.000 0.873 0.127
E25.9 Adrenogenital disorder, unspecified
0.000 0.875 0.125
E25.8 Other adrenogenital disorders
0.000 0.875 0.125
E61.9 Deficiency of nutrient element, unspecified
0.000 0.875 0.125
E61.8 Deficiency of other specified nutrient elements
0.000 0.875 0.125
E61.7 Deficiency of multiple nutrient elements
0.000 0.875 0.125
E61.6 Vanadium deficiency
0.000 0.875 0.125
E61.5 Molybdenum deficiency
0.000 0.875 0.125
E61.4 Chromium deficiency
0.000 0.875 0.125
E61.3 Manganese deficiency
0.000 0.875 0.125
E61.0 Copper deficiency
0.000 0.875 0.125
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.875 0.125
E20.9 Hypoparathyroidism, unspecified
0.000 0.875 0.124
E83.8 Other disorders of mineral metabolism
0.122 0.876 0.003
E83.2 Disorders of zinc metabolism
0.122 0.876 0.003
E83.0 Disorders of copper metabolism
0.122 0.876 0.003
E53.9 Vitamin B deficiency, unspecified
0.000 0.876 0.123
E31.9 Polyglandular dysfunction, unspecified
0.000 0.877 0.123
E31.8 Other polyglandular dysfunction
0.000 0.877 0.123
E31.1 Polyglandular hyperfunction
0.000 0.877 0.123
E83.9 Disorder of mineral metabolism, unspecified
0.121 0.877 0.003
E11.8 With unspecified complications
0.000 0.877 0.123
E26 Hyperaldosteronism
0.000 0.879 0.121
E14.9 Without complications
0.000 0.879 0.121
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.879 0.120
E63.9 Nutritional deficiency, unspecified
0.000 0.881 0.119
I83 Varicose veins of lower extremities
0.117 0.883 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.884 0.116
C25 Malignant neoplasm of pancreas
0.000 0.885 0.115
E53.1 Pyridoxine deficiency
0.000 0.886 0.114
E53.0 Riboflavin deficiency
0.000 0.886 0.114
S02.4 Fracture of malar and maxillary bones
0.000 0.887 0.113
C15.5 Lower third of oesophagus
0.000 0.889 0.111
E61.1 Iron deficiency
0.000 0.891 0.109
E29.9 Testicular dysfunction, unspecified
0.000 0.891 0.109
E29.8 Other testicular dysfunction
0.000 0.891 0.109
E29.0 Testicular hyperfunction
0.000 0.891 0.109
C15.4 Middle third of oesophagus
0.000 0.892 0.108
E61.2 Magnesium deficiency
0.000 0.893 0.107
S02 Fracture of skull and facial bones
0.000 0.893 0.107
E21.0 Primary hyperparathyroidism
0.000 0.894 0.106
C17 Malignant neoplasm of small intestine
0.000 0.894 0.106
E22 Hyperfunction of pituitary gland
0.000 0.894 0.106
E34.3 Short stature, not elsewhere classified
0.000 0.898 0.101
E28.9 Ovarian dysfunction, unspecified
0.000 0.899 0.101
E28.8 Other ovarian dysfunction
0.000 0.899 0.101
E28.1 Androgen excess
0.000 0.899 0.101
E28.0 Oestrogen excess
0.000 0.899 0.101
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.899 0.101
C17.0 Duodenum
0.000 0.899 0.101
E34.5 Androgen resistance syndrome
0.000 0.900 0.099
E34.4 Constitutional tall stature
0.000 0.900 0.099
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.900 0.099
E34.1 Other hypersecretion of intestinal hormones
0.000 0.900 0.099
C15.9 Oesophagus, unspecified
0.000 0.901 0.099
C25.3 Pancreatic duct
0.000 0.904 0.096
C25.1 Body of pancreas
0.000 0.905 0.095
C15.0 Cervical part of oesophagus
0.000 0.905 0.095
S02.0 Fracture of vault of skull
0.000 0.905 0.095
C25.2 Tail of pancreas
0.000 0.906 0.094
E55.9 Vitamin D deficiency, unspecified
0.000 0.908 0.092
E34.9 Endocrine disorder, unspecified
0.000 0.908 0.092
S02.8 Fractures of other skull and facial bones
0.000 0.908 0.092
C15.8 Overlapping lesion of oesophagus
0.000 0.909 0.091
C15.2 Abdominal part of oesophagus
0.000 0.909 0.091
C24.0 Extrahepatic bile duct
0.000 0.909 0.090
S02.6 Fracture of mandible
0.000 0.910 0.090
C25.4 Endocrine pancreas
0.000 0.910 0.090
C15.1 Thoracic part of oesophagus
0.000 0.911 0.089
E34.8 Other specified endocrine disorders
0.000 0.913 0.087
E26.8 Other hyperaldosteronism
0.000 0.913 0.087
E26.1 Secondary hyperaldosteronism
0.000 0.913 0.087
C25.8 Overlapping lesion of pancreas
0.000 0.913 0.087
E28.3 Primary ovarian failure
0.000 0.914 0.086
S02.00 Fracture of vault of skull (closed)
0.000 0.914 0.086
E34.0 Carcinoid syndrome
0.000 0.914 0.085
S02.3 Fracture of orbital floor
0.000 0.915 0.085
S02.7 Multiple fractures involving skull and facial bones
0.000 0.915 0.085
S02.5 Fracture of tooth
0.000 0.916 0.084
C15.3 Upper third of oesophagus
0.000 0.916 0.083
E28.2 Polycystic ovarian syndrome
0.000 0.916 0.083
S02.2 Fracture of nasal bones
0.000 0.918 0.082
E29.1 Testicular hypofunction
0.000 0.919 0.081
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.919 0.081
C21 Malignant neoplasm of anus and anal canal
0.000 0.921 0.079
S02.60 Fracture of mandible (closed)
0.000 0.922 0.078
I83.0 Varicose veins of lower extremities with ulcer
0.078 0.922 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.922 0.077
C17.8 Overlapping lesion of small intestine
0.000 0.924 0.076
C17.3 Meckel's diverticulum
0.000 0.924 0.076
E11.3 With ophthalmic complications
0.000 0.924 0.076
E22.8 Other hyperfunction of pituitary gland
0.000 0.924 0.076
C25.9 Pancreas, unspecified
0.000 0.924 0.076
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.924 0.076
C25.7 Other parts of pancreas
0.000 0.924 0.076
E22.1 Hyperprolactinaemia
0.000 0.925 0.075
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.073 0.927 0.000
C24.8 Overlapping lesion of biliary tract
0.000 0.927 0.072
C17.1 Jejunum
0.000 0.927 0.072
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.928 0.072
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.929 0.071
C24.9 Biliary tract, unspecified
0.000 0.930 0.070
S02.30 Fracture of orbital floor (closed)
0.000 0.930 0.070
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.930 0.070
S02.21 Fracture of nasal bones (open)
0.000 0.930 0.070
S02.50 Fracture of tooth (closed)
0.000 0.932 0.068
S02.01 Fracture of vault of skull (open)
0.000 0.932 0.068
S02.81 Fractures of other skull and facial bones (open)
0.000 0.934 0.066
E11.5 With peripheral circulatory complications
0.000 0.935 0.065
M45 Ankylosing spondylitis
0.065 0.935 0.000
S02.61 Fracture of mandible (open)
0.000 0.935 0.065
E23 Hypofunction and other disorders of pituitary gland
0.000 0.936 0.064
C23 Malignant neoplasm of gallbladder
0.000 0.936 0.064
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.937 0.063
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.938 0.062
S02.31 Fracture of orbital floor (open)
0.000 0.939 0.061
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.939 0.061
S02.51 Fracture of tooth (open)
0.000 0.939 0.061
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.939 0.060
E83.4 Disorders of magnesium metabolism
0.057 0.941 0.002
S02.1 Fracture of base of skull
0.000 0.942 0.058
C21.2 Cloacogenic zone
0.000 0.943 0.057
C17.9 Small intestine, unspecified
0.000 0.943 0.057
E22.0 Acromegaly and pituitary gigantism
0.000 0.943 0.056
Z71.8 Other specified counselling
0.053 0.947 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.947 0.053
M45.X2 Ankylosing spondylitis (Cervical region)
0.052 0.948 0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.949 0.051
E23.7 Disorder of pituitary gland, unspecified
0.000 0.949 0.051
C17.2 Ileum
0.000 0.950 0.050
E26.0 Primary hyperaldosteronism
0.001 0.950 0.049
M45.X6 Ankylosing spondylitis (Lumbar region)
0.050 0.950 0.000
S02.20 Fracture of nasal bones (closed)
0.000 0.951 0.049
C22.9 Liver, unspecified
0.000 0.953 0.047
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.047 0.953 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.047 0.953 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.047 0.953 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.047 0.953 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.047 0.953 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.047 0.953 0.000
E04 Other non-toxic goitre
0.002 0.953 0.045
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.954 0.046
E23.1 Drug-induced hypopituitarism
0.000 0.954 0.046
C18.9 Colon, unspecified
0.000 0.954 0.046
C18 Malignant neoplasm of colon
0.000 0.954 0.046
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.954 0.046
C21.1 Anal canal
0.000 0.955 0.045
C22.7 Other specified carcinomas of liver
0.000 0.955 0.045
C22.4 Other sarcomas of liver
0.000 0.955 0.045
C22.3 Angiosarcoma of liver
0.000 0.955 0.045
C22.2 Hepatoblastoma
0.000 0.955 0.045
C21.0 Anus, unspecified
0.000 0.956 0.044
C26.8 Overlapping lesion of digestive system
0.000 0.956 0.043
C26.1 Spleen
0.000 0.956 0.043
C18.1 Appendix
0.000 0.957 0.043
C22.1 Intrahepatic bile duct carcinoma
0.000 0.958 0.042
E27 Other disorders of adrenal gland
0.000 0.959 0.041
S02.11 Fracture of base of skull (open)
0.000 0.959 0.040
C25.0 Head of pancreas
0.000 0.959 0.041
C24.1 Ampulla of Vater
0.001 0.960 0.039
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.038 0.962 0.000
E11.4 With neurological complications
0.000 0.964 0.036
C18.8 Overlapping lesion of colon
0.000 0.965 0.035
I83.1 Varicose veins of lower extremities with inflammation
0.035 0.965 0.000
E04.8 Other specified non-toxic goitre
0.002 0.966 0.032
E53.8 Deficiency of other specified B group vitamins
0.000 0.967 0.033
C26.9 Ill-defined sites within the digestive system
0.000 0.968 0.032
S00-S09 Injuries to the head
0.000 0.968 0.032
C18.4 Transverse colon
0.000 0.969 0.031
E27.1 Primary adrenocortical insufficiency
0.000 0.969 0.031
S05 Injury of eye and orbit
0.000 0.969 0.031
E27.5 Adrenomedullary hyperfunction
0.000 0.970 0.029
E27.0 Other adrenocortical overactivity
0.000 0.970 0.029
E11.9 Without complications
0.000 0.971 0.029
E23.6 Other disorders of pituitary gland
0.001 0.971 0.028
C26.0 Intestinal tract, part unspecified
0.000 0.971 0.028
K90-K93 Other diseases of the digestive system
0.000 0.971 0.028
E23.2 Diabetes insipidus
0.000 0.972 0.028
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.973 0.027
E70-E90 Metabolic disorders
0.002 0.973 0.024
E27.9 Disorder of adrenal gland, unspecified
0.000 0.974 0.026
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.974 0.026
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.974 0.026
S00 Superficial injury of head
0.000 0.974 0.026
S02.10 Fracture of base of skull (closed)
0.000 0.975 0.025
E27.2 Addisonian crisis
0.000 0.975 0.025
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.975 0.025
I77 Other disorders of arteries and arterioles
0.000 0.975 0.025
S05.8 Other injuries of eye and orbit
0.000 0.975 0.025
I77.6 Arteritis, unspecified
0.000 0.975 0.025
E66 Obesity
0.000 0.976 0.024
E04.0 Non-toxic diffuse goitre
0.002 0.976 0.022
C18.6 Descending colon
0.000 0.976 0.024
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.976 0.024
S00.0 Superficial injury of scalp
0.000 0.976 0.024
S07 Crushing injury of head
0.000 0.977 0.023
S04 Injury of cranial nerves
0.000 0.977 0.023
I77.8 Other specified disorders of arteries and arterioles
0.000 0.977 0.023
C18.7 Sigmoid colon
0.000 0.977 0.023
S08 Traumatic amputation of part of head
0.000 0.977 0.023
C16 Malignant neoplasm of stomach
0.000 0.977 0.023
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.978 0.022
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.978 0.022
S05.7 Avulsion of eye
0.000 0.978 0.022
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.978 0.022
I77.1 Stricture of artery
0.000 0.978 0.022
S05.1 Contusion of eyeball and orbital tissues
0.000 0.978 0.022
E78.2 Mixed hyperlipidaemia
0.000 0.978 0.022
S00.4 Superficial injury of ear
0.000 0.978 0.021
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.979 0.021
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.979 0.020
S00.1 Contusion of eyelid and periocular area
0.000 0.980 0.020
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.980 0.020
S09 Other and unspecified injuries of head
0.000 0.980 0.020
E73 Lactose intolerance
0.001 0.980 0.019
K14.8 Other diseases of tongue
0.000 0.980 0.020
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.980 0.019
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.980 0.018
E23.0 Hypopituitarism
0.000 0.980 0.019
E78.5 Hyperlipidaemia, unspecified
0.000 0.981 0.019
E78.1 Pure hyperglyceridaemia
0.000 0.981 0.019
E77 Disorders of glycoprotein metabolism
0.002 0.981 0.017
E76 Disorders of glycosaminoglycan metabolism
0.002 0.981 0.017
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.002 0.981 0.017
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.002 0.981 0.017
E74 Other disorders of carbohydrate metabolism
0.002 0.981 0.018
C18.3 Hepatic flexure
0.000 0.981 0.019
H40.2 Primary angle-closure glaucoma
0.019 0.981 0.000
S05.9 Injury of eye and orbit, part unspecified
0.000 0.981 0.019
E27.8 Other specified disorders of adrenal gland
0.000 0.981 0.018
E85 Amyloidosis
0.001 0.981 0.017
E70 Disorders of aromatic amino-acid metabolism
0.002 0.981 0.017
S09.8 Other specified injuries of head
0.000 0.981 0.019
I77.2 Rupture of artery
0.000 0.981 0.018
I77.3 Arterial fibromuscular dysplasia
0.000 0.981 0.018
I77.5 Necrosis of artery
0.000 0.982 0.018
I77.4 Coeliac artery compression syndrome
0.000 0.982 0.018
S00.7 Multiple superficial injuries of head
0.000 0.982 0.018
E72 Other disorders of amino-acid metabolism
0.002 0.982 0.016
E79 Disorders of purine and pyrimidine metabolism
0.002 0.982 0.016
E78.6 Lipoprotein deficiency
0.000 0.982 0.018
E66.1 Drug-induced obesity
0.000 0.982 0.017
E88 Other metabolic disorders
0.001 0.982 0.017
E84 Cystic fibrosis
0.002 0.983 0.015
E78.3 Hyperchylomicronaemia
0.000 0.983 0.017
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.017 0.983 0.000
S04.9 Injury of unspecified cranial nerve
0.000 0.983 0.017
S04.8 Injury of other cranial nerves
0.000 0.983 0.017
S04.7 Injury of accessory nerve
0.000 0.983 0.017
S04.6 Injury of acoustic nerve
0.000 0.983 0.017
S04.5 Injury of facial nerve
0.000 0.983 0.017
S04.4 Injury of abducent nerve
0.000 0.983 0.017
S04.3 Injury of trigeminal nerve
0.000 0.983 0.017
S04.2 Injury of trochlear nerve
0.000 0.983 0.017
S04.1 Injury of oculomotor nerve
0.000 0.983 0.017
S04.0 Injury of optic nerve and pathways
0.000 0.983 0.017
S07.9 Crushing injury of head, part unspecified
0.000 0.983 0.017
S07.8 Crushing injury of other parts of head
0.000 0.983 0.017
S07.1 Crushing injury of skull
0.000 0.983 0.017
S07.0 Crushing injury of face
0.000 0.983 0.017
S08.9 Traumatic amputation of unspecified part of head
0.000 0.983 0.016
S08.8 Traumatic amputation of other parts of head
0.000 0.983 0.016
S08.0 Avulsion of scalp
0.000 0.983 0.016
S08.1 Traumatic amputation of ear
0.000 0.984 0.016
S00.5 Superficial injury of lip and oral cavity
0.000 0.984 0.016
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.984 0.016
S03.0 Dislocation of jaw
0.000 0.984 0.016
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.016 0.984 0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head
0.000 0.984 0.015
S03.4 Sprain and strain of jaw
0.000 0.984 0.015
S03.3 Dislocation of other and unspecified parts of head
0.000 0.984 0.015
C16.2 Body of stomach
0.000 0.985 0.015
E73.9 Lactose intolerance, unspecified
0.001 0.985 0.015
C16.5 Lesser curvature of stomach, unspecified
0.000 0.985 0.015
I89.0 Lymphoedema, not elsewhere classified
0.015 0.985 0.000
S03.2 Dislocation of tooth
0.000 0.985 0.015
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.985 0.015
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.985 0.015
K93.1 Megacolon in Chagas' disease
0.000 0.985 0.015
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.985 0.015

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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