TreeWAS – Variant ID: rs2219939

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I20.9 Angina pectoris, unspecified	0.000	0.000	1.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.001	0.999
I20.8 Other forms of angina pectoris	0.000	0.006	0.994
I25.2 Old myocardial infarction	0.000	0.014	0.986
I24 Other acute ischaemic heart diseases	0.000	0.074	0.926
I21 Acute myocardial infarction	0.000	0.082	0.918
I21.9 Acute myocardial infarction, unspecified	0.000	0.090	0.910
I20.0 Unstable angina	0.000	0.112	0.888
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.140	0.860
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.156	0.844
I20.1 Angina pectoris with documented spasm	0.000	0.161	0.839
I24.1 Dressler's syndrome	0.000	0.180	0.820
I23 Certain current complications following acute myocardial infarction	0.000	0.201	0.799
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.230	0.770
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.240	0.760
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.253	0.747
I25.6 Silent myocardial ischaemia	0.000	0.258	0.742
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.342	0.658
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.350	0.650
I25.4 Coronary artery aneurysm	0.000	0.358	0.642
I23.8 Other current complications following acute myocardial infarction	0.000	0.360	0.639
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.406	0.594
I24.8 Other forms of acute ischaemic heart disease	0.000	0.423	0.577
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.427	0.573
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.427	0.573
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.427	0.573
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.427	0.573
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.427	0.573
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.427	0.573
I22 Subsequent myocardial infarction	0.000	0.449	0.551
I25.3 Aneurysm of heart	0.000	0.455	0.545
I21.4 Acute subendocardial myocardial infarction	0.000	0.481	0.519
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.559	0.441
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.571	0.429
I21.3 Acute transmural myocardial infarction of unspecified site	0.001	0.571	0.428
I22.8 Subsequent myocardial infarction of other sites	0.000	0.617	0.383
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.632	0.368
I25.5 Ischaemic cardiomyopathy	0.000	0.654	0.345
Z95.1 Presence of aortocoronary bypass graft	0.000	0.761	0.239
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.766	0.234
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.795	0.205
Z95.3 Presence of xenogenic heart valve	0.000	0.801	0.199
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.808	0.192
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.001	0.942	0.057
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.979	0.020
N81.2 Incomplete uterovaginal prolapse	0.000	0.979	0.021
N81 Female genital prolapse	0.000	0.981	0.019
N81.9 Female genital prolapse, unspecified	0.000	0.982	0.018
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.018	0.982	0.000
N81.5 Vaginal enterocele	0.000	0.982	0.018
M35.0 Sicca syndrome [Sjogren]	0.000	0.983	0.017
I71 Aortic aneurysm and dissection	0.017	0.983	0.000
N81.8 Other female genital prolapse	0.000	0.983	0.017
I77 Other disorders of arteries and arterioles	0.016	0.984	0.000
N81.0 Female urethrocele	0.000	0.984	0.016
I72 Other aneurysm	0.015	0.985	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.015	0.985	0.000
N81.6 Rectocele	0.000	0.985	0.015
I70-I79 Diseases of arteries, arterioles and capillaries	0.015	0.985	0.000
I77.0 Arteriovenous fistula, acquired	0.015	0.985	0.000
I72.0 Aneurysm of carotid artery	0.015	0.985	0.000
I72.8 Aneurysm of other specified arteries	0.014	0.986	0.000
I77.8 Other specified disorders of arteries and arterioles	0.014	0.986	0.000
I77.2 Rupture of artery	0.014	0.986	0.000
N81.3 Complete uterovaginal prolapse	0.000	0.986	0.014
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.014	0.986	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.013	0.987	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.987	0.013
I78 Diseases of capillaries	0.013	0.987	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.013	0.987	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.987	0.012
I71.0 Dissection of aorta [any part]	0.012	0.988	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.012	0.988	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.012	0.988	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.012	0.988	0.000
I78.8 Other diseases of capillaries	0.012	0.988	0.000
I72.4 Aneurysm of artery of lower extremity	0.012	0.988	0.000
N81.1 Cystocele	0.000	0.988	0.012
I72.2 Aneurysm of renal artery	0.012	0.988	0.000
I77.5 Necrosis of artery	0.012	0.988	0.000
I77.4 Coeliac artery compression syndrome	0.012	0.988	0.000
I77.6 Arteritis, unspecified	0.012	0.988	0.000
I70 Atherosclerosis	0.012	0.988	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.012	0.988	0.000
M35 Other systemic involvement of connective tissue	0.000	0.988	0.012
I72.6 Aneurysm and dissection of vertebral artery	0.011	0.989	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.011	0.989	0.000
I72.9 Aneurysm of unspecified site	0.011	0.989	0.000
I72.1 Aneurysm of artery of upper extremity	0.010	0.989	0.000
M35.7 Hypermobility syndrome	0.000	0.989	0.010
I77.3 Arterial fibromuscular dysplasia	0.010	0.990	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.010	0.990	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.010	0.990	0.000
M35.1 Other overlap syndromes	0.000	0.990	0.010
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.010	0.990	0.000
E21.3 Hyperparathyroidism, unspecified	0.010	0.990	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.009	0.990	0.000
E21.0 Primary hyperparathyroidism	0.010	0.990	0.000
I70.0 Atherosclerosis of aorta	0.009	0.990	0.000
I70.8 Atherosclerosis of other arteries	0.009	0.991	0.000
I78.9 Disease of capillaries, unspecified	0.009	0.991	0.000
I70.9 Generalised and unspecified atherosclerosis	0.009	0.991	0.000
M35.2 Behcet's disease	0.000	0.991	0.009
I72.3 Aneurysm of iliac artery	0.008	0.991	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.991	0.008
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.991	0.008
M35.5 Multifocal fibrosclerosis	0.000	0.991	0.008
N28.1 Cyst of kidney, acquired	0.008	0.992	0.000
M35.3 Polymyalgia rheumatica	0.000	0.992	0.008
Z95.0 Presence of cardiac pacemaker	0.000	0.992	0.008
Z71.3 Dietary counselling and surveillance	0.008	0.992	0.000
E21.2 Other hyperparathyroidism	0.008	0.992	0.000
I70.1 Atherosclerosis of renal artery	0.008	0.992	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.008	0.992	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.992	0.008
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.992	0.008
M35.8 Other specified systemic involvement of connective tissue	0.000	0.992	0.008
I70.2 Atherosclerosis of arteries of the extremities	0.008	0.992	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.008	0.992	0.000
E21.4 Other specified disorders of parathyroid gland	0.007	0.993	0.000
E34 Other endocrine disorders	0.007	0.993	0.000
E22 Hyperfunction of pituitary gland	0.007	0.993	0.000
I79.1 Aortitis in diseases classified elsewhere	0.007	0.993	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.007	0.993	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.007	0.993	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.007	0.993	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.007	0.993	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.007	0.993	0.000
E20-E35 Disorders of other endocrine glands	0.007	0.993	0.000
E34.9 Endocrine disorder, unspecified	0.007	0.993	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.007	0.993	0.000
E22.0 Acromegaly and pituitary gigantism	0.007	0.993	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.007	0.993	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.006	0.993	0.000
S92.5 Fracture of other toe	0.000	0.993	0.007
E34.0 Carcinoid syndrome	0.007	0.993	0.000
S92.51 Fracture of other toe (open)	0.000	0.993	0.006
E34.8 Other specified endocrine disorders	0.006	0.994	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.994	0.006
I78.1 Naevus, nonneoplastic	0.006	0.994	0.000
S92.50 Fracture of other toe (closed)	0.000	0.994	0.006
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.006	0.994	0.000
I74 Arterial embolism and thrombosis	0.006	0.994	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.006	0.994	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.006	0.994	0.000
S92 Fracture of foot, except ankle	0.000	0.994	0.006
S92.00 Fracture of calcaneus (closed)	0.000	0.994	0.006
E22.1 Hyperprolactinaemia	0.006	0.994	0.000
S92.0 Fracture of calcaneus	0.000	0.994	0.006
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.006	0.994	0.000
E32 Diseases of thymus	0.006	0.994	0.000
E34.5 Androgen resistance syndrome	0.005	0.994	0.000
E34.4 Constitutional tall stature	0.005	0.994	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.005	0.994	0.000
E34.1 Other hypersecretion of intestinal hormones	0.005	0.994	0.000
E20 Hypoparathyroidism	0.005	0.994	0.000
E22.8 Other hyperfunction of pituitary gland	0.005	0.995	0.000
E34.3 Short stature, not elsewhere classified	0.005	0.995	0.000
E25 Adrenogenital disorders	0.005	0.995	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.005	0.995	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E30 Disorders of puberty, not elsewhere classified	0.005	0.995	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.005	0.995	0.000
E31 Polyglandular dysfunction	0.005	0.995	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.005	0.995	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.005	0.995	0.000
S92.2 Fracture of other tarsal bone(s)	0.000	0.995	0.005
N28 Other disorders of kidney and ureter, not elsewhere classified	0.005	0.995	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.005	0.995	0.000
S92.4 Fracture of great toe	0.000	0.995	0.005
E28 Ovarian dysfunction	0.005	0.995	0.000
E29 Testicular dysfunction	0.005	0.995	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.005	0.995	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.995	0.004
E32.8 Other diseases of thymus	0.004	0.995	0.000
L03.9 Cellulitis, unspecified	0.000	0.995	0.005
I74.8 Embolism and thrombosis of other arteries	0.004	0.995	0.000
S92.1 Fracture of talus	0.000	0.996	0.004
E32.9 Disease of thymus, unspecified	0.004	0.996	0.000
N28.0 Ischaemia and infarction of kidney	0.004	0.996	0.000
E23 Hypofunction and other disorders of pituitary gland	0.004	0.996	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.004	0.996	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.996	0.004
S92.40 Fracture of great toe (closed)	0.000	0.996	0.004
E20.9 Hypoparathyroidism, unspecified	0.004	0.996	0.000
E26 Hyperaldosteronism	0.004	0.996	0.000
S92.3 Fracture of metatarsal bone	0.000	0.996	0.004
E20.8 Other hypoparathyroidism	0.004	0.996	0.000
E32.1 Abscess of thymus	0.004	0.996	0.000
E32.0 Persistent hyperplasia of thymus	0.004	0.996	0.000
E20.1 Pseudohypoparathyroidism	0.004	0.996	0.000
E20.0 Idiopathic hypoparathyroidism	0.004	0.996	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.004	0.996	0.000
I77.1 Stricture of artery	0.004	0.996	0.000
S92.9 Fracture of foot, unspecified	0.000	0.996	0.004
E25.9 Adrenogenital disorder, unspecified	0.004	0.996	0.000
E25.8 Other adrenogenital disorders	0.004	0.996	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.004	0.996	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.004	0.996	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.004	0.996	0.000
S92.7 Multiple fractures of foot	0.000	0.996	0.004
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.996	0.004
E30.9 Disorder of puberty, unspecified	0.004	0.996	0.000
E30.8 Other disorders of puberty	0.004	0.996	0.000
E30.1 Precocious puberty	0.004	0.996	0.000
E30.0 Delayed puberty	0.004	0.996	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.004	0.996	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.004	0.996	0.000
E31.9 Polyglandular dysfunction, unspecified	0.004	0.996	0.000
E31.8 Other polyglandular dysfunction	0.004	0.996	0.000
E31.1 Polyglandular hyperfunction	0.004	0.996	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.996	0.004
E31.0 Autoimmune polyglandular failure	0.004	0.996	0.000
E28.3 Primary ovarian failure	0.004	0.996	0.000
S91.0 Open wound of ankle	0.000	0.996	0.004
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.996	0.004
S90-S99 Injuries to the ankle and foot	0.000	0.996	0.004
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.004	0.996	0.000
E28.9 Ovarian dysfunction, unspecified	0.004	0.996	0.000
E28.8 Other ovarian dysfunction	0.004	0.996	0.000
E28.1 Androgen excess	0.004	0.996	0.000
E28.0 Oestrogen excess	0.004	0.996	0.000
S99.9 Unspecified injury of ankle and foot	0.000	0.996	0.004
S99 Other and unspecified injuries of ankle and foot	0.000	0.996	0.004
E27 Other disorders of adrenal gland	0.004	0.996	0.000
N28.8 Other specified disorders of kidney and ureter	0.004	0.996	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.996	0.004
E29.8 Other testicular dysfunction	0.003	0.996	0.000
E29.0 Testicular hyperfunction	0.003	0.996	0.000
E24 Cushing's syndrome	0.003	0.996	0.000
S92.10 Fracture of talus (closed)	0.000	0.996	0.003
E29.9 Testicular dysfunction, unspecified	0.003	0.996	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.004	0.996	0.000
C53.9 Cervix uteri, unspecified	0.004	0.996	0.000
E23.6 Other disorders of pituitary gland	0.003	0.996	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.997	0.000
S91 Open wound of ankle and foot	0.000	0.997	0.003
S92.41 Fracture of great toe (open)	0.000	0.997	0.003
E26.8 Other hyperaldosteronism	0.003	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.003	0.997	0.000
S92.31 Fracture of metatarsal bone (open)	0.000	0.997	0.003
E23.0 Hypopituitarism	0.003	0.997	0.000
I74.5 Embolism and thrombosis of iliac artery	0.003	0.997	0.000
S92.91 Fracture of foot, unspecified (open)	0.000	0.997	0.003
I73 Other peripheral vascular diseases	0.003	0.997	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.000	0.997	0.003
S92.11 Fracture of talus (open)	0.000	0.997	0.003
S92.71 Multiple fractures of foot (open)	0.000	0.997	0.003
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.000	0.997	0.003
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.997	0.003
S98 Traumatic amputation of ankle and foot	0.000	0.997	0.003
S92.30 Fracture of metatarsal bone (closed)	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
T51.0 Ethanol	0.003	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
L03.3 Cellulitis of trunk	0.000	0.997	0.003
T51.9 Alcohol, unspecified	0.003	0.997	0.000
R05 Cough	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.000	0.997	0.003
S94 Injury of nerves at ankle and foot level	0.000	0.997	0.003
G70.0 Myasthenia gravis	0.003	0.997	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.003	0.997	0.000
N76.2 Acute vulvitis	0.003	0.997	0.000
S93.0 Dislocation of ankle joint	0.000	0.997	0.003
S99.8 Other specified injuries of ankle and foot	0.000	0.997	0.003
S99.7 Multiple injuries of ankle and foot	0.000	0.997	0.003
E27.5 Adrenomedullary hyperfunction	0.003	0.997	0.000
E27.0 Other adrenocortical overactivity	0.003	0.997	0.000
S92.90 Fracture of foot, unspecified (closed)	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.997	0.003
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.003	0.997	0.000
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
F60.9 Personality disorder, unspecified	0.000	0.997	0.003
Z89.6 Acquired absence of leg above knee	0.000	0.997	0.003
S90 Superficial injury of ankle and foot	0.000	0.997	0.003
E27.2 Addisonian crisis	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.997	0.000
C81.9 Hodgkin's disease, unspecified	0.003	0.997	0.000
E26.0 Primary hyperaldosteronism	0.003	0.997	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.997	0.003
S92.70 Multiple fractures of foot (closed)	0.000	0.997	0.002
S97.1 Crushing injury of toe(s)	0.000	0.997	0.003
N04.9 Unspecified	0.003	0.997	0.000
S98.1 Traumatic amputation of one toe	0.000	0.997	0.002
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.997	0.003
M50.2 Other cervical disk displacement	0.003	0.997	0.000
J84 Other interstitial pulmonary diseases	0.003	0.997	0.000
E23.2 Diabetes insipidus	0.002	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.997	0.002
D75.0 Familial erythrocytosis	0.003	0.997	0.000
S90.0 Contusion of ankle	0.000	0.997	0.002
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.997	0.002
S97.0 Crushing injury of ankle	0.000	0.997	0.002
T51 Toxic effect of alcohol	0.003	0.997	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.997	0.002
E24.0 Pituitary-dependent Cushing's disease	0.002	0.997	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.997	0.002
S98.3 Traumatic amputation of other parts of foot	0.000	0.997	0.002
S98.2 Traumatic amputation of two or more toes	0.000	0.997	0.002
S98.0 Traumatic amputation of foot at ankle level	0.000	0.997	0.002
S90.3 Contusion of other and unspecified parts of foot	0.000	0.997	0.002
M25.86 Other specified joint disorders (Lower leg)	0.002	0.997	0.000
H60.8 Other otitis externa	0.002	0.997	0.000
J84.0 Alveolar and parietoalveolar conditions	0.002	0.997	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.998	0.002
S94.8 Injury of other nerves at ankle and foot level	0.000	0.998	0.002
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.998	0.002
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.998	0.002
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.998	0.002
S94.1 Injury of medial plantar nerve	0.000	0.998	0.002
S94.0 Injury of lateral plantar nerve	0.000	0.998	0.002
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.998	0.002
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.998	0.002
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.998	0.002
S95.2 Injury of dorsal vein of foot	0.000	0.998	0.002
S95.1 Injury of plantar artery of foot	0.000	0.998	0.002
S95.0 Injury of dorsal artery of foot	0.000	0.998	0.002
E24.8 Other Cushing's syndrome	0.002	0.998	0.001
S91.1 Open wound of toe(s) without damage to nail	0.000	0.998	0.002
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.998	0.002
D75 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
W07.0 Home	0.000	0.998	0.002
S93.4 Sprain and strain of ankle	0.000	0.998	0.002
S93.5 Sprain and strain of toe(s)	0.000	0.998	0.002
D75.2 Essential thrombocytosis	0.002	0.998	0.000
J84.8 Other specified interstitial pulmonary diseases	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.998	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.998	0.002
S90.2 Contusion of toe(s) with damage to nail	0.000	0.998	0.002
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.998	0.002
T18.1 Foreign body in oesophagus	0.000	0.998	0.002
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.002	0.998	0.000
Z89.9 Acquired absence of limb, unspecified	0.000	0.998	0.002
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.998	0.002
S90.1 Contusion of toe(s) without damage to nail	0.000	0.998	0.002
Z71.8 Other specified counselling	0.002	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
S91.3 Open wound of other parts of foot	0.000	0.998	0.002
D75.1 Secondary polycythaemia	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
S71.1 Open wound of thigh	0.000	0.998	0.002
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.998	0.002
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
O80.9 Single spontaneous delivery, unspecified	0.000	0.998	0.002
T51.8 Other alcohols	0.002	0.998	0.000
T51.3 Fusel oil	0.002	0.998	0.000
T51.2 2-Propanol	0.002	0.998	0.000
T51.1 Methanol	0.002	0.998	0.000
J00 Acute nasopharyngitis [common cold]	0.002	0.998	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.998	0.002
G70 Myasthenia gravis and other myoneural disorders	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
M51.9 Intervertebral disk disorder, unspecified	0.002	0.998	0.000
Z89 Acquired absence of limb	0.000	0.998	0.002
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.998	0.002
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.000	0.998	0.002
S93.40 Sprain of unspecified ligament of ankle	0.000	0.998	0.002
G93.9 Disorder of brain, unspecified	0.002	0.998	0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.002	0.998	0.000
C53 Malignant neoplasm of cervix uteri	0.002	0.998	0.000
J80 Adult respiratory distress syndrome	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
C67.6 Ureteric orifice	0.002	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
G70.9 Myoneural disorder, unspecified	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.998	0.002
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.998	0.002
Z71.7 Human immunodeficiency virus [HIV] counselling	0.002	0.998	0.000
Z71.5 Drug abuse counselling and surveillance	0.002	0.998	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.002	0.998	0.000
Z71.0 Person consulting on behalf of another person	0.002	0.998	0.000
N04 Nephrotic syndrome	0.002	0.998	0.000
C90.0 Multiple myeloma	0.000	0.998	0.002
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.998	0.002
J92.0 Pleural plaque with presence of asbestos	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.998	0.002
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.002	0.998	0.000
M47.89 Other spondylosis (Site unspecified)	0.000	0.998	0.002
C53.0 Endocervix	0.002	0.998	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.000	0.998	0.002
S82.8 Fractures of other parts of lower leg	0.000	0.998	0.002
N04.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
H60 Otitis externa	0.002	0.998	0.000
C67.1 Dome of bladder	0.002	0.998	0.000
G70.8 Other specified myoneural disorders	0.002	0.998	0.000
G70.2 Congenital and developmental myasthenia	0.002	0.998	0.000
G70.1 Toxic myoneural disorders	0.002	0.998	0.000
C17.9 Small intestine, unspecified	0.002	0.998	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.998	0.002
Z89.1 Acquired absence of hand and wrist	0.000	0.998	0.002
L03.8 Cellulitis of other sites	0.000	0.998	0.002
Z71.9 Counselling, unspecified	0.002	0.998	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.998	0.002
O82 Single delivery by Caesarean section	0.000	0.998	0.002
J43.9 Emphysema, unspecified	0.002	0.998	0.000
N04.0 Minor glomerular abnormality	0.002	0.998	0.000
S31.0 Open wound of lower back and pelvis	0.000	0.998	0.002
V89.3 Person injured in unspecified nonmotor-vehicle accident, traffic	0.000	0.998	0.002
V89.1 Person injured in unspecified nonmotor-vehicle accident, nontraffic	0.000	0.998	0.002
V89.0 Person injured in unspecified motor-vehicle accident, nontraffic	0.000	0.998	0.002
Z89.2 Acquired absence of upper limb above wrist	0.000	0.998	0.002
C53.8 Overlapping lesion of cervix uteri	0.002	0.998	0.000
C53.1 Exocervix	0.002	0.998	0.000
L53.9 Erythematous condition, unspecified	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
N25-N29 Other disorders of kidney and ureter	0.002	0.998	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.002	0.998	0.000
Y83.4 Other reconstructive surgery	0.000	0.998	0.002
N04.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
N04.8 Other	0.001	0.998	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.001	0.998	0.000
N04.6 Dense deposit disease	0.001	0.998	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.998	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.998	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.998	0.000
H60.3 Other infective otitis externa	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.000	0.998	0.001
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.002	0.998	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.001
C67.4 Posterior wall of bladder	0.002	0.998	0.000
H60.0 Abscess of external ear	0.002	0.998	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.998	0.002
L03 Cellulitis	0.000	0.998	0.002
M80 Osteoporosis with pathological fracture	0.000	0.998	0.002
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.998	0.002
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.001	0.998	0.000
Z73.8 Other problems related to life-management difficulty	0.000	0.998	0.002
C67.3 Anterior wall of bladder	0.002	0.998	0.000
S82.86 Maisonneuve's fracture	0.000	0.998	0.001
K07.6 Temporomandibular joint disorders	0.000	0.998	0.002
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.998	0.002
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
H60.5 Acute otitis externa, non-infective	0.001	0.998	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.998	0.002
R46.8 Other symptoms and signs involving appearance and behaviour	0.000	0.998	0.002
V89.9 Person injured in unspecified vehicle accident	0.000	0.998	0.001
S31 Open wound of abdomen, lower back and pelvis	0.000	0.998	0.002
S42.20 Fracture of upper end of humerus (closed)	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.002	0.998	0.000
I44.6 Other and unspecified fascicular block	0.002	0.998	0.000
K56.1 Intussusception	0.000	0.998	0.002
O04.4 Incomplete, without complication	0.000	0.998	0.002
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.001
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.998	0.002
S71.0 Open wound of hip	0.000	0.998	0.001
M77.57 Other enthesopathy of foot-Ankle/Foot	0.000	0.998	0.001
S82.81 Fractures of other parts of lower leg (open)	0.000	0.998	0.001
C67.8 Overlapping lesion of bladder	0.001	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.000	0.998	0.001
O82.2 Delivery by Caesarean hysterectomy	0.000	0.998	0.001
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.001	0.998	0.000
S31.1 Open wound of abdominal wall	0.000	0.998	0.001
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.998	0.001
C67 Malignant neoplasm of bladder	0.002	0.998	0.000
N27 Small kidney of unknown cause	0.001	0.998	0.000
M87.2 Osteonecrosis due to previous trauma	0.000	0.999	0.001
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations