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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2227956
log Bayes Factor = 126.303
Chromosome 6   position 31,778,272  (GRCh37) Explore rs2227956 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.001 0.999
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
G20-G26 Extrapyramidal and movement disorders
0.998 0.002 0.000
G20 Parkinson's disease
0.998 0.002 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E14 Unspecified diabetes mellitus
0.000 0.004 0.996
E16 Other disorders of pancreatic internal secretion
0.000 0.004 0.996
E07 Other disorders of thyroid
0.000 0.004 0.996
E83.1 Disorders of iron metabolism
0.995 0.005 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.006 0.994
E16.2 Hypoglycaemia, unspecified
0.000 0.007 0.993
G37 Other demyelinating diseases of central nervous system
0.992 0.008 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.013 0.987
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.014 0.986
G37.9 Demyelinating disease of central nervous system, unspecified
0.982 0.018 0.000
E14.3 With ophthalmic complications
0.000 0.019 0.981
M06 Other rheumatoid arthritis
0.000 0.020 0.980
L40 Psoriasis
0.969 0.031 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.039 0.961
G40-G47 Episodic and paroxysmal disorders
0.950 0.050 0.000
H36.0 Diabetic retinopathy
0.000 0.053 0.947
J33.9 Nasal polyp, unspecified
0.000 0.054 0.946
G40 Epilepsy
0.946 0.054 0.000
J33 Nasal polyp
0.000 0.055 0.945
E14.9 Without complications
0.000 0.060 0.940
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.062 0.938
E10.5 With peripheral circulatory complications
0.000 0.064 0.936
H36 Retinal disorders in diseases classified elsewhere
0.000 0.073 0.927
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.074 0.926
J33.0 Polyp of nasal cavity
0.000 0.074 0.926
E11 Non-insulin-dependent diabetes mellitus
0.000 0.075 0.925
M05-M14 Inflammatory polyarthropathies
0.000 0.077 0.923
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.079 0.921
L40.0 Psoriasis vulgaris
0.920 0.080 0.000
J45 Asthma
0.000 0.080 0.920
M45 Ankylosing spondylitis
0.000 0.081 0.919
E10.2 With renal complications
0.000 0.082 0.918
I10-I15 Hypertensive diseases
0.000 0.086 0.914
H30-H36 Disorders of choroid and retina
0.000 0.088 0.912
L40.5 Arthropathic psoriasis
0.910 0.090 0.000
I10 Essential (primary) hypertension
0.000 0.092 0.908
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.905 0.095 0.000
I12 Hypertensive renal disease
0.000 0.099 0.901
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.900 0.100 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.100 0.900
E83 Disorders of mineral metabolism
0.892 0.101 0.007
J40-J47 Chronic lower respiratory diseases
0.000 0.105 0.895
E10.0 With coma
0.000 0.111 0.889
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.111 0.889
Chapter X Diseases of the respiratory system
0.000 0.112 0.888
M45-M49 Spondylopathies
0.000 0.114 0.886
E10.8 With unspecified complications
0.000 0.115 0.885
I12.9 Hypertensive renal disease without renal failure
0.000 0.116 0.884
# Top node
0.001 0.116 0.883
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.117 0.883
E11.9 Without complications
0.000 0.125 0.875
Chapter VII Diseases of the eye and adnexa
0.000 0.125 0.875
J30-J39 Other diseases of upper respiratory tract
0.000 0.125 0.875
Chapter IX Diseases of the circulatory system
0.000 0.130 0.870
E13 Other specified diabetes mellitus
0.000 0.130 0.870
H43-H45 Disorders of vitreous body and globe
0.000 0.136 0.864
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.136 0.864
I15 Secondary hypertension
0.000 0.137 0.863
H43 Disorders of vitreous body
0.000 0.137 0.863
H43.8 Other disorders of vitreous body
0.000 0.141 0.859
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.142 0.858
I20-I25 Ischaemic heart diseases
0.000 0.142 0.858
G37.8 Other specified demyelinating diseases of central nervous system
0.857 0.143 0.000
J33.8 Other polyp of sinus
0.000 0.145 0.855
I22 Subsequent myocardial infarction
0.000 0.147 0.853
H35 Other retinal disorders
0.000 0.147 0.853
E06 Thyroiditis
0.000 0.153 0.847
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.162 0.838
J86 Pyothorax
0.000 0.166 0.834
E83.3 Disorders of phosphorus metabolism
0.832 0.167 0.002
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.169 0.831
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.175 0.825
H35.8 Other specified retinal disorders
0.000 0.176 0.824
E11.0 With coma
0.000 0.177 0.823
M06.3 Rheumatoid nodule
0.000 0.179 0.821
G24 Dystonia
0.817 0.183 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.186 0.814
M06.4 Inflammatory polyarthropathy
0.000 0.186 0.814
E83.5 Disorders of calcium metabolism
0.808 0.192 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.197 0.803
E10.6 With other specified complications
0.000 0.197 0.803
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.199 0.801
E16.1 Other hypoglycaemia
0.000 0.199 0.801
G46 Vascular syndromes of brain in cerebrovascular diseases
0.797 0.203 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.203 0.797
I15.1 Hypertension secondary to other renal disorders
0.000 0.203 0.797
G41 Status epilepticus
0.793 0.207 0.000
J44 Other chronic obstructive pulmonary disease
0.000 0.213 0.787
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.214 0.786
J86.9 Pyothorax without fistula
0.000 0.216 0.784
G30-G32 Other degenerative diseases of the nervous system
0.784 0.216 0.000
I20 Angina pectoris
0.000 0.219 0.781
E03.8 Other specified hypothyroidism
0.000 0.220 0.780
M65-M68 Disorders of synovium and tendon
0.000 0.222 0.778
E13.9 Without complications
0.000 0.223 0.777
M06.0 Seronegative rheumatoid arthritis
0.000 0.224 0.776
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.226 0.774
I12.0 Hypertensive renal disease with renal failure
0.000 0.228 0.772
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.232 0.768
G40.5 Special epileptic syndromes
0.766 0.234 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.764 0.236 0.000
J46 Status asthmaticus
0.000 0.246 0.754
G25 Other extrapyramidal and movement disorders
0.750 0.250 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.250 0.749
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.749 0.251 0.000
G40.9 Epilepsy, unspecified
0.749 0.251 0.000
E11.5 With peripheral circulatory complications
0.000 0.253 0.747
M65 Synovitis and tenosynovitis
0.000 0.254 0.746
J37 Chronic laryngitis and laryngotracheitis
0.000 0.258 0.742
I20.1 Angina pectoris with documented spasm
0.000 0.260 0.740
H35.4 Peripheral retinal degeneration
0.000 0.261 0.739
E14.1 With ketoacidosis
0.000 0.267 0.733
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.267 0.733
I15.9 Seconday hypertension, unspecified
0.000 0.268 0.732
G40.7 Petit mal, unspecified, without grand mal seizures
0.731 0.269 0.000
J86.0 Pyothorax with fistula
0.000 0.272 0.728
M06.34 Rheumatoid nodule (Hand)
0.000 0.272 0.728
J85 Abscess of lung and mediastinum
0.000 0.272 0.728
H34 Retinal vascular occlusions
0.000 0.273 0.727
H43.9 Disorder of vitreous body, unspecified
0.000 0.276 0.724
H31 Other disorders of choroid
0.000 0.278 0.722
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.279 0.721
E83.9 Disorder of mineral metabolism, unspecified
0.716 0.279 0.004
G24.9 Dystonia, unspecified
0.720 0.280 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.281 0.719
J42 Unspecified chronic bronchitis
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.716 0.284 0.000
G23 Other degenerative diseases of basal ganglia
0.716 0.284 0.000
G21 Secondary Parkinsonism
0.716 0.284 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.716 0.284 0.000
G22 Parkinsonism in diseases classified elsewhere
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
E14.8 With unspecified complications
0.000 0.286 0.714
E14.7 With multiple complications
0.000 0.286 0.714
E14.5 With peripheral circulatory complications
0.000 0.286 0.714
E14.2 Withrenal complications
0.000 0.286 0.714
E14.0 With coma
0.000 0.286 0.714
E14.6 With other specified complications
0.000 0.286 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.286 0.714
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.286 0.714
E16.4 Abnormal secretion of gastrin
0.000 0.286 0.714
E16.3 Increased secretion of glucagon
0.000 0.286 0.714
E07.1 Dyshormogenetic goitre
0.000 0.286 0.714
E07.0 Hypersecretion of calcitonin
0.000 0.286 0.714
E06.3 Autoimmune thyroiditis
0.000 0.287 0.713
E14.4 With neurological complications
0.000 0.288 0.712
I20.9 Angina pectoris, unspecified
0.000 0.288 0.712
G37.5 Concentric sclerosis [Balo]
0.711 0.289 0.000
G37.4 Subacute necrotising myelitis
0.711 0.289 0.000
G37.2 Central pontine myelinolysis
0.711 0.289 0.000
G37.1 Central demyelination of corpus callosum
0.711 0.289 0.000
G37.0 Diffuse sclerosis
0.711 0.289 0.000
K90 Intestinal malabsorption
0.000 0.289 0.711
E11.1 With ketoacidosis
0.000 0.291 0.709
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.708 0.292 0.000
L40.1 Generalised pustular psoriasis
0.707 0.293 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.294 0.706
M06.8 Other specified rheumatoid arthritis
0.000 0.297 0.703
M06.2 Rheumatoid bursitis
0.000 0.297 0.703
M06.1 Adult-onset Still's disease
0.000 0.297 0.703
H43.2 Crystalline deposits in vitreous body
0.000 0.298 0.702
L40.3 Pustulosis palmaris et plantaris
0.701 0.299 0.000
E05.8 Other thyrotoxicosis
0.000 0.300 0.700
G00-G09 Inflammatory diseases of the central nervous system
0.699 0.301 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.302 0.698
L40.4 Guttate psoriasis
0.695 0.305 0.000
L40.2 Acrodermatitis continua
0.695 0.305 0.000
H35.2 Other proliferative retinopathy
0.000 0.316 0.684
H43.3 Other vitreous opacities
0.000 0.320 0.680
G40.4 Other generalised epilepsy and epileptic syndromes
0.678 0.322 0.000
J33.1 Polypoid sinus degeneration
0.000 0.323 0.677
L40.8 Other psoriasis
0.677 0.323 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.326 0.673
G40.8 Other epilepsy
0.668 0.331 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.335 0.664
E11.7 With multiple complications
0.000 0.337 0.663
G41.0 Grand mal status epilepticus
0.663 0.337 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.338 0.662
M08 Juvenile arthritis
0.000 0.338 0.662
J45.8 Mixed asthma
0.000 0.340 0.659
J45.1 Nonallergic asthma
0.000 0.340 0.659
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.341 0.659
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.341 0.659
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.341 0.659
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.341 0.659
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.341 0.659
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.341 0.659
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.341 0.659
H30 Chorioretinal inflammation
0.000 0.341 0.658
I23 Certain current complications following acute myocardial infarction
0.000 0.342 0.658
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.343 0.657
I13 Hypertensive heart and renal disease
0.000 0.345 0.655
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.346 0.654
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.347 0.653
H35.5 Hereditary retinal dystrophy
0.000 0.347 0.653
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.347 0.652
H35.6 Retinal haemorrhage
0.000 0.350 0.650
E06.9 Thyroiditis, unspecified
0.000 0.351 0.649
J37.0 Chronic laryngitis
0.000 0.352 0.648
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.646 0.353 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.355 0.645
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.355 0.645
M05.2 Rheumatoid vasculitis
0.000 0.355 0.645
M05.1 Rheumatoid lung disease
0.000 0.355 0.645
M05.0 Felty's syndrome
0.000 0.355 0.645
E83.8 Other disorders of mineral metabolism
0.639 0.356 0.005
E83.2 Disorders of zinc metabolism
0.639 0.356 0.005
E83.0 Disorders of copper metabolism
0.639 0.356 0.005
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.356 0.644
J41 Simple and mucopurulent chronic bronchitis
0.000 0.358 0.642
J95-J99 Other diseases of the respiratory system
0.000 0.359 0.641
G46.7 Other lacunar syndromes
0.641 0.359 0.000
E40-E46 Malnutrition
0.000 0.360 0.640
G46.4 Cerebellar stroke syndrome
0.640 0.360 0.000
E11.6 With other specified complications
0.000 0.362 0.638
K90.9 Intestinal malabsorption, unspecified
0.000 0.364 0.636
Chapter XVI Certain conditions originating in the perinatal period
0.001 0.366 0.633
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.367 0.633
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.367 0.633
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.367 0.633
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.367 0.633
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.367 0.633
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.367 0.633
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.367 0.633
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.367 0.633
M49 Spondylopathies in diseases classified elsewhere
0.000 0.368 0.632
G24.8 Other dystonia
0.625 0.375 0.000
H35.7 Separation of retinal layers
0.000 0.376 0.624
E13.8 With unspecified complications
0.000 0.376 0.624
E13.7 With multiple complications
0.000 0.376 0.624
E13.6 With other specified complications
0.000 0.376 0.624
E13.5 With peripheral circulatory complications
0.000 0.376 0.624
E13.4 With neurological complications
0.000 0.376 0.624
E13.3 With ophthalmic complications
0.000 0.376 0.624
E13.2 With renal complications
0.000 0.376 0.624
E13.1 With ketoacidosis
0.000 0.376 0.624
E13.0 With coma
0.000 0.376 0.624
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.380 0.620
M11 Other crystal arthropathies
0.000 0.380 0.620
I15.8 Other secondary hypertension
0.000 0.381 0.619
I15.2 Hypertension secondary to endocrine disorders
0.000 0.381 0.619
I15.0 Renovascular hypertension
0.000 0.381 0.619
H43.0 Vitreous prolapse
0.000 0.381 0.619
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.619 0.381 0.000
E11.8 With unspecified complications
0.000 0.384 0.616
H35.1 Retinopathy of prematurity
0.000 0.388 0.611
E07.8 Other specified disorders of thyroid
0.000 0.391 0.609
M12 Other specific arthropathies
0.000 0.392 0.608
E06.5 Other chronic thyroiditis
0.000 0.393 0.607
E06.4 Drug-induced thyroiditis
0.000 0.393 0.607
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.393 0.607
E06.1 Subacute thyroiditis
0.000 0.393 0.607
E06.0 Acute thyroiditis
0.000 0.393 0.607
I24 Other acute ischaemic heart diseases
0.000 0.393 0.607
M80-M85 Disorders of bone density and structure
0.000 0.394 0.606
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.394 0.605
I00-I02 Acute rheumatic fever
0.000 0.397 0.603
E70-E90 Metabolic disorders
0.015 0.399 0.586
G41.9 Status epilepticus, unspecified
0.598 0.401 0.000
I11 Hypertensive heart disease
0.000 0.402 0.598
J85.2 Abscess of lung without pneumonia
0.000 0.405 0.595
H31.0 Chorioretinal scars
0.000 0.405 0.595
E11.2 With renal complications
0.000 0.409 0.591
G25.1 Drug-induced tremor
0.590 0.410 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.412 0.588
M06.38 Rheumatoid nodule (Other)
0.000 0.412 0.588
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.412 0.588
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.412 0.588
M06.33 Rheumatoid nodule (Forearm)
0.000 0.412 0.588
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.412 0.588
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.412 0.588
G24.4 Idiopathic orofacial dystonia
0.585 0.414 0.000
G24.2 Idiopathic nonfamilial dystonia
0.585 0.414 0.000
G24.1 Idiopathic familial dystonia
0.585 0.414 0.000
G24.0 Drug-induced dystonia
0.585 0.414 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.416 0.583
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.416 0.583
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.416 0.583
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.416 0.583
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.416 0.583
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.416 0.583
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.416 0.583
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.416 0.583
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.583 0.416 0.000
G11 Hereditary ataxia
0.583 0.417 0.000
G24.3 Spasmodic torticollis
0.583 0.417 0.000
M14 Arthropathies in other diseases classified elsewhere
0.000 0.417 0.583
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.418 0.582
E78.0 Pure hypercholesterolaemia
0.000 0.421 0.579
G70-G73 Diseases of myoneural junction and muscle
0.577 0.423 0.000
J85.1 Abscess of lung with pneumonia
0.000 0.424 0.576
H35.9 Retinal disorder, unspecified
0.000 0.424 0.576
J31.2 Chronic pharyngitis
0.000 0.424 0.576
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.572 0.428 0.000
G46.6 Pure sensory lacunar syndrome
0.572 0.428 0.000
G46.5 Pure motor lacunar syndrome
0.572 0.428 0.000
G46.3 Brain stem stroke syndrome
0.572 0.428 0.000
G46.2 Posterior cerebral artery syndrome
0.572 0.428 0.000
G46.1 Anterior cerebral artery syndrome
0.572 0.428 0.000
G46.0 Middle cerebral artery syndrome
0.572 0.428 0.000
M65.1 Other infective (teno)synovitis
0.000 0.431 0.569
G41.8 Other status epilepticus
0.568 0.431 0.000
G41.2 Complex partial status epilepticus
0.568 0.431 0.000
G41.1 Petit mal status epilepticus
0.568 0.431 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.432 0.568
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.434 0.566
H34.8 Other retinal vascular occlusions
0.000 0.435 0.564
G00 Bacterial meningitis, not elsewhere classified
0.564 0.436 0.000
M65.8 Other synovitis and tenosynovitis
0.000 0.436 0.564
J31.0 Chronic rhinitis
0.000 0.439 0.561
M82 Osteoporosis in diseases classified elsewhere
0.000 0.439 0.561
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.442 0.558
E11.3 With ophthalmic complications
0.000 0.443 0.557
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.443 0.557
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.443 0.557
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.443 0.557
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.443 0.557
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.443 0.557
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.443 0.557
K90.8 Other intestinal malabsorption
0.000 0.444 0.556
G25.3 Myoclonus
0.556 0.444 0.000
G30 Alzheimer's disease
0.554 0.445 0.000
H34.1 Central retinal artery occlusion
0.000 0.446 0.554
G83 Other paralytic syndromes
0.551 0.449 0.000
H31.1 Choroidal degeneration
0.000 0.450 0.550
G81 Hemiplegia
0.550 0.450 0.000
G25.2 Other specified forms of tremor
0.548 0.452 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.540 0.460 0.000
H34.2 Other retinal artery occlusions
0.000 0.460 0.539
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.461 0.539
G25.6 Drug-induced tics and other tics of organic origin
0.538 0.462 0.000
G25.5 Other chorea
0.538 0.462 0.000
G25.4 Drug-induced chorea
0.538 0.462 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.537 0.463 0.000
G03 Meningitis due to other and unspecified causes
0.536 0.464 0.000
M65.2 Calcific tendinitis
0.000 0.465 0.535
M65.0 Abscess of tendon sheath
0.000 0.465 0.535
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.465 0.535
G25.9 Extrapyramidal and movement disorder, unspecified
0.534 0.465 0.000
J37.1 Chronic laryngotracheitis
0.000 0.468 0.532
M82.1 Osteoporosis in endocrine disorders
0.000 0.471 0.529
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.528 0.472 0.000
I22.8 Subsequent myocardial infarction of other sites
0.000 0.473 0.527
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.475 0.525
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.475 0.525
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.475 0.525
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.475 0.525
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.475 0.525
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.475 0.525
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.475 0.525
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.475 0.525
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.476 0.524
G09 Sequelae of inflammatory diseases of central nervous system
0.523 0.477 0.000
G90-G99 Other disorders of the nervous system
0.523 0.477 0.000
J85.3 Abscess of mediastinum
0.000 0.478 0.522
J85.0 Gangrene and necrosis of lung
0.000 0.478 0.522
H34.0 Transient retinal artery occlusion
0.000 0.479 0.521
H25-H28 Disorders of lens
0.000 0.479 0.521
E78.2 Mixed hyperlipidaemia
0.000 0.479 0.521
M00-M03 Infectious arthropathies
0.000 0.479 0.521
H31.9 Disorder of choroid, unspecified
0.000 0.482 0.518
H31.4 Choroidal detachment
0.000 0.482 0.518
H31.3 Choroidal haemorrhage and rupture
0.000 0.482 0.518
H31.2 Hereditary choroidal dystrophy
0.000 0.482 0.518
M60-M63 Disorders of muscles
0.000 0.484 0.516
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.002 0.484 0.514
J31.1 Chronic nasopharyngitis
0.000 0.484 0.516
I23.8 Other current complications following acute myocardial infarction
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
G36.9 Acute disseminated demyelination, unspecified
0.514 0.486 0.000
G36.8 Other specified acute disseminated demyelination
0.514 0.486 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.514 0.486 0.000
G36.0 Neuromyelitis optica [Devic]
0.514 0.486 0.000
G21.9 Secondary Parkinsonism, unspecified
0.513 0.487 0.000
G21.8 Other secondary Parkinsonism
0.513 0.487 0.000
G21.4 Vascular parkinsonism
0.513 0.487 0.000
G21.3 Postencephalitic Parkinsonism
0.513 0.487 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.513 0.487 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.513 0.487 0.000
G21.0 Malignant neuroleptic syndrome
0.513 0.487 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.513 0.487 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.513 0.487 0.000
G23.3 Multiple system atrophy, cerebellar type
0.513 0.487 0.000
G23.2 Striatonigral degeneration
0.513 0.487 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.513 0.487 0.000
G23.0 Hallervorden-Spatz disease
0.513 0.487 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.488 0.512
K90.3 Pancreatic steatorrhoea
0.000 0.490 0.510
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.490 0.510
K90.1 Tropical sprue
0.000 0.490 0.510
I05-I09 Chronic rheumatic heart diseases
0.000 0.492 0.508
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.507 0.492 0.000
G10 Huntington's disease
0.507 0.492 0.000
H34.9 Retinal vascular occlusion, unspecified
0.000 0.494 0.506
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.496 0.504
M06.18 Adult-onset Still's disease (Other)
0.000 0.496 0.504
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.496 0.504
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.496 0.504
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.496 0.504
M06.14 Adult-onset Still's disease (Hand)
0.000 0.496 0.504
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.496 0.504
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.496 0.504
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.496 0.504
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.496 0.504
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.496 0.504
M06.28 Rheumatoid bursitis (Other)
0.000 0.496 0.504
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.496 0.504
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.496 0.504
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.496 0.504
M06.24 Rheumatoid bursitis (Hand)
0.000 0.496 0.504
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.496 0.504
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.496 0.504
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.496 0.504
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.496 0.504
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.496 0.504
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.496 0.504
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.496 0.504
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.496 0.504
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.496 0.504
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.496 0.504
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.496 0.504
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.496 0.504
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.496 0.504
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.496 0.504
G14 Postpolio syndrome
0.503 0.497 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.501 0.499 0.000
J32 Chronic sinusitis
0.000 0.500 0.500
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.501 0.499
M15-M19 Arthrosis
0.000 0.508 0.492
H43.1 Vitreous haemorrhage
0.000 0.509 0.491
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.511 0.489
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.000 0.514 0.486
G25.0 Essential tremor
0.484 0.515 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.483 0.517 0.000
G44 Other headache syndromes
0.483 0.517 0.000
H27 Other disorders of lens
0.000 0.518 0.482
G06 Intracranial and intraspinal abscess and granuloma
0.481 0.519 0.000
G11.4 Hereditary spastic paraplegia
0.481 0.519 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.000 0.520 0.480
J60-J70 Lung diseases due to external agents
0.000 0.521 0.478
H30.9 Chorioretinal inflammation, unspecified
0.000 0.523 0.476
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.524 0.476
M18 Arthrosis of first carpometacarpal joint
0.000 0.524 0.476
M08.9 Juvenile arthritis, unspecified
0.000 0.525 0.474
M08.8 Other juvenile arthritis
0.000 0.525 0.474
M08.4 Pauciarticular juvenile arthritis
0.000 0.525 0.474

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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