TreeWAS – Variant ID: rs223296

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I20 Angina pectoris	0.999	0.001	0.000
I20.9 Angina pectoris, unspecified	0.998	0.002	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.990	0.010	0.000
I20.0 Unstable angina	0.949	0.051	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.892	0.108	0.000
I21 Acute myocardial infarction	0.876	0.124	0.000
I25.3 Aneurysm of heart	0.820	0.180	0.000
I21.4 Acute subendocardial myocardial infarction	0.805	0.195	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.785	0.215	0.000
I22 Subsequent myocardial infarction	0.773	0.227	0.000
I24 Other acute ischaemic heart diseases	0.770	0.230	0.000
I23 Certain current complications following acute myocardial infarction	0.753	0.247	0.000
I25.2 Old myocardial infarction	0.742	0.258	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.737	0.263	0.000
I20.8 Other forms of angina pectoris	0.719	0.281	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283	0.000
I25.4 Coronary artery aneurysm	0.697	0.303	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.697	0.303	0.000
I20.1 Angina pectoris with documented spasm	0.677	0.323	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.628	0.372	0.000
I24.8 Other forms of acute ischaemic heart disease	0.611	0.389	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.588	0.412	0.000
I25.5 Ischaemic cardiomyopathy	0.587	0.413	0.000
I23.8 Other current complications following acute myocardial infarction	0.576	0.424	0.000
I24.1 Dressler's syndrome	0.552	0.448	0.000
I22.8 Subsequent myocardial infarction of other sites	0.551	0.449	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.540	0.460	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.540	0.460	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.540	0.460	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.540	0.460	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.540	0.460	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.540	0.460	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.540	0.460	0.000
I21.9 Acute myocardial infarction, unspecified	0.514	0.486	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.508	0.492	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.498	0.502	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.406	0.594	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.397	0.603	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.339	0.661	0.000
Z95.1 Presence of aortocoronary bypass graft	0.076	0.924	0.000
Chapter IX Diseases of the circulatory system	0.017	0.983	0.000
D12.3 Transverse colon	0.017	0.983	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.016	0.984	0.000
I27 Other pulmonary heart diseases	0.016	0.984	0.000
I27.0 Primary pulmonary hypertension	0.015	0.985	0.000
I05-I09 Chronic rheumatic heart diseases	0.015	0.985	0.000
D12.6 Colon, unspecified	0.014	0.986	0.000
I27.9 Pulmonary heart disease, unspecified	0.014	0.986	0.000
D12.5 Sigmoid colon	0.013	0.987	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.013	0.987	0.000
I28 Other diseases of pulmonary vessels	0.013	0.987	0.000
I00-I02 Acute rheumatic fever	0.013	0.987	0.000
I05 Rheumatic mitral valve diseases	0.012	0.987	0.000
I27.2 Other secondary pulmonary hypertension	0.012	0.988	0.000
I05.0 Mitral stenosis	0.012	0.988	0.000
I07 Rheumatic tricuspid valve diseases	0.012	0.988	0.000
I27.1 Kyphoscoliotic heart disease	0.011	0.988	0.000
I27.8 Other specified pulmonary heart diseases	0.011	0.989	0.000
I09 Other rheumatic heart diseases	0.011	0.989	0.000
I06 Rheumatic aortic valve diseases	0.011	0.989	0.000
I28.8 Other specified diseases of pulmonary vessels	0.010	0.989	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.010	0.990	0.000
I10-I15 Hypertensive diseases	0.010	0.990	0.000
D12.1 Appendix	0.010	0.990	0.000
I05.2 Mitral stenosis with insufficiency	0.010	0.990	0.000
D12.0 Caecum	0.010	0.990	0.000
I07.1 Tricuspid insufficiency	0.009	0.990	0.000
D12.9 Anus and anal canal	0.009	0.990	0.000
I08 Multiple valve diseases	0.009	0.991	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.009	0.991	0.000
I28.1 Aneurysm of pulmonary artery	0.009	0.991	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.009	0.991	0.000
D12.2 Ascending colon	0.009	0.991	0.000
I02 Rheumatic chorea	0.009	0.991	0.000
I01 Rheumatic fever with heart involvement	0.009	0.991	0.000
I00 Rheumatic fever without mention of heart involvement	0.009	0.991	0.000
I05.8 Other mitral valve diseases	0.009	0.991	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.009	0.991	0.000
I07.9 Tricuspid valve disease, unspecified	0.008	0.991	0.000
I07.8 Other tricuspid valve diseases	0.008	0.991	0.000
I07.2 Tricuspid stenosis with insufficiency	0.008	0.991	0.000
I07.0 Tricuspid stenosis	0.008	0.991	0.000
I05.1 Rheumatic mitral insufficiency	0.008	0.991	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.008	0.992	0.000
D12.7 Rectosigmoid junction	0.008	0.992	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.008	0.992	0.000
I15 Secondary hypertension	0.008	0.992	0.000
I08.0 Disorders of both mitral and aortic valves	0.008	0.992	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.008	0.992	0.000
I06.8 Other rheumatic aortic valve diseases	0.008	0.992	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.008	0.992	0.000
I06.1 Rheumatic aortic insufficiency	0.008	0.992	0.000
I06.0 Rheumatic aortic stenosis	0.008	0.992	0.000
I09.9 Rheumatic heart disease, unspecified	0.008	0.992	0.000
I09.8 Other specified rheumatic heart diseases	0.008	0.992	0.000
I09.2 Chronic rheumatic pericarditis	0.008	0.992	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.008	0.992	0.000
I09.0 Rheumatic myocarditis	0.008	0.992	0.000
I26 Pulmonary embolism	0.008	0.992	0.000
I60-I69 Cerebrovascular diseases	0.008	0.992	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.007	0.992	0.000
I49.9 Cardiac arrhythmia, unspecified	0.008	0.992	0.000
I60 Subarachnoid haemorrhage	0.007	0.992	0.000
I05.9 Mitral valve disease, unspecified	0.007	0.992	0.000
I11 Hypertensive heart disease	0.007	0.993	0.000
I12 Hypertensive renal disease	0.007	0.993	0.000
I13 Hypertensive heart and renal disease	0.007	0.993	0.000
I08.9 Multiple valve disease, unspecified	0.007	0.993	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.007	0.993	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.007	0.993	0.000
I01.8 Other acute rheumatic heart disease	0.007	0.993	0.000
I01.2 Acute rheumatic myocarditis	0.007	0.993	0.000
I01.1 Acute rheumatic endocarditis	0.007	0.993	0.000
I01.0 Acute rheumatic pericarditis	0.007	0.993	0.000
I02.9 Rheumatic chorea without heart involvement	0.007	0.993	0.000
I02.0 Rheumatic chorea with heart involvement	0.007	0.993	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.007	0.993	0.000
I15.1 Hypertension secondary to other renal disorders	0.007	0.993	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.007	0.993	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.007	0.993	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.006	0.993	0.000
I63 Cerebral infarction	0.006	0.994	0.000
I95 Hypotension	0.006	0.994	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.006	0.994	0.000
I08.8 Other multiple valve diseases	0.006	0.994	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.006	0.994	0.000
I97.0 Postcardiotomy syndrome	0.006	0.994	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.006	0.994	0.000
I99 Other and unspecified disorders of circulatory system	0.006	0.994	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.006	0.994	0.000
D12.4 Descending colon	0.006	0.994	0.000
I15.9 Seconday hypertension, unspecified	0.006	0.994	0.000
I15.8 Other secondary hypertension	0.006	0.994	0.000
I15.2 Hypertension secondary to endocrine disorders	0.006	0.994	0.000
I15.0 Renovascular hypertension	0.006	0.994	0.000
I69 Sequelae of cerebrovascular disease	0.006	0.994	0.000
I60.8 Other subarachnoid haemorrhage	0.006	0.994	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.006	0.994	0.000
I97.1 Other functional disturbances following cardiac surgery	0.006	0.994	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.006	0.994	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.006	0.994	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.006	0.994	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.006	0.994	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.006	0.994	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.006	0.994	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.006	0.994	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.006	0.994	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.006	0.994	0.000
I12.0 Hypertensive renal disease with renal failure	0.006	0.994	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.005	0.994	0.000
I12.9 Hypertensive renal disease without renal failure	0.005	0.994	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.005	0.994	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.005	0.994	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.005	0.994	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.005	0.994	0.000
I95.2 Hypotension due to drugs	0.005	0.994	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.005	0.995	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.995	0.005
M47.82 Other spondylosis (Cervical region)	0.005	0.995	0.000
T39.1 4-Aminophenol derivatives	0.000	0.995	0.005
I69.0 Sequelae of subarachnoid haemorrhage	0.005	0.995	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.005	0.995	0.000
I69.3 Sequelae of cerebral infarction	0.005	0.995	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.005	0.995	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.005	0.995	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.005	0.995	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
I98.0 Cardiovascular syphilis	0.005	0.995	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.005	0.995	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.005	0.995	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.005	0.995	0.000
I95.0 Idiopathic hypotension	0.005	0.995	0.000
I95.9 Hypotension, unspecified	0.005	0.995	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.005	0.995	0.000
I95.8 Other hypotension	0.005	0.995	0.000
E86 Volume depletion	0.005	0.995	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.005	0.995	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.004	0.995	0.000
O36.9 Maternal care for foetal problem, unspecified	0.005	0.995	0.000
O36 Maternal care for other known or suspected foetal problems	0.005	0.995	0.000
C18.0 Caecum	0.000	0.996	0.004
I62 Other nontraumatic intracranial haemorrhage	0.004	0.996	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.996	0.004
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.004	0.996	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.004	0.996	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.004	0.996	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.004	0.996	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.004	0.996	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.004	0.996	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.004	0.996	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.004	0.996	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.004	0.996	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
I68.0 Cerebral amyloid angiopathy	0.004	0.996	0.000
O36.8 Maternal care for other specified foetal problems	0.004	0.996	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.004	0.996	0.000
Z36 Antenatal screening	0.000	0.996	0.004
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.004	0.996	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.004	0.996	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.004	0.996	0.000
I65.1 Occlusion and stenosis of basilar artery	0.004	0.996	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.004	0.996	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.004	0.996	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.004	0.996	0.000
Z36.8 Other antenatal screening	0.000	0.996	0.004
O36.4 Maternal care for intra-uterine death	0.004	0.996	0.000
I61 Intracerebral haemorrhage	0.004	0.996	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.004	0.996	0.000
Z95.4 Presence of other heart-valve replacement	0.004	0.996	0.000
Z95.3 Presence of xenogenic heart valve	0.004	0.996	0.000
I65.2 Occlusion and stenosis of carotid artery	0.004	0.996	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.004	0.996	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.004	0.996	0.000
I63.8 Other cerebral infarction	0.004	0.996	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.996	0.004
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.004	0.996	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.003	0.996	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.003	0.996	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.003	0.996	0.000
O36.2 Maternal care for hydrops foetalis	0.003	0.996	0.000
O36.1 Maternal care for other isoimmunisation	0.003	0.996	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.996	0.003
M47.89 Other spondylosis (Site unspecified)	0.003	0.997	0.000
I62.1 Nontraumatic extradural haemorrhage	0.003	0.997	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
R63.4 Abnormal weight loss	0.000	0.997	0.003
M47.8 Other spondylosis	0.003	0.997	0.000
Z36.5 Antenatal screening for isoimmunisation	0.000	0.997	0.003
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.997	0.003
N43.3 Hydrocele, unspecified	0.003	0.997	0.000
O36.5 Maternal care for poor foetal growth	0.003	0.997	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.997	0.003
Z95.2 Presence of prosthetic heart valve	0.003	0.997	0.000
C18 Malignant neoplasm of colon	0.000	0.997	0.003
I49 Other cardiac arrhythmias	0.003	0.997	0.000
C71.2 Temporal lobe	0.003	0.997	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.003	0.997	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.003	0.997	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.003	0.997	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.003	0.997	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.003	0.997	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.003	0.997	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
E23.0 Hypopituitarism	0.003	0.997	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.997	0.003
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.003	0.997	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
C71.1 Frontal lobe	0.003	0.997	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.003	0.997	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.003	0.997	0.000
K56.2 Volvulus	0.000	0.997	0.003
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
I61.8 Other intracerebral haemorrhage	0.003	0.997	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.997	0.003
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.997	0.003
T39.4 Antirheumatics, not elsewhere classified	0.000	0.997	0.003
T39.2 Pyrazolone derivatives	0.000	0.997	0.003
N41.9 Inflammatory disease of prostate, unspecified	0.003	0.997	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.997	0.003
C71 Malignant neoplasm of brain	0.003	0.997	0.000
N41.0 Acute prostatitis	0.003	0.997	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.003	0.997	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.003	0.997	0.000
C18.9 Colon, unspecified	0.000	0.997	0.003
C71.9 Brain, unspecified	0.003	0.997	0.000
I49.1 Atrial premature depolarisation	0.003	0.997	0.000
N41.1 Chronic prostatitis	0.003	0.997	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
N41 Inflammatory diseases of prostate	0.003	0.997	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.997	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.003	0.997	0.000
M47.84 Other spondylosis (Thoracic region)	0.003	0.997	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.003	0.997	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.003	0.997	0.000
I95.1 Orthostatic hypotension	0.003	0.997	0.000
O36.6 Maternal care for excessive foetal growth	0.002	0.997	0.000
C18.2 Ascending colon	0.000	0.997	0.003
C18.4 Transverse colon	0.000	0.997	0.003
C18.1 Appendix	0.000	0.997	0.003
C18.8 Overlapping lesion of colon	0.000	0.997	0.002
E89.2 Postprocedural hypoparathyroidism	0.003	0.997	0.000
I49.2 Junctional premature depolarisation	0.002	0.997	0.000
C18.7 Sigmoid colon	0.000	0.997	0.003
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.003	0.997	0.000
C18.6 Descending colon	0.000	0.997	0.002
E28.2 Polycystic ovarian syndrome	0.002	0.997	0.000
T39.0 Salicylates	0.000	0.997	0.002
E23 Hypofunction and other disorders of pituitary gland	0.002	0.997	0.000
C18.5 Splenic flexure	0.000	0.997	0.002
I49.8 Other specified cardiac arrhythmias	0.002	0.997	0.000
R22.0 Localised swelling, mass and lump, head	0.002	0.997	0.000
I49.3 Ventricular premature depolarisation	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
E89.3 Postprocedural hypopituitarism	0.002	0.998	0.000
I44.0 Atrioventricular block, first degree	0.000	0.998	0.002
I61.9 Intracerebral haemorrhage, unspecified	0.002	0.998	0.000
D12.8 Rectum	0.002	0.998	0.000
B37.8 Candidiasis of other sites	0.002	0.998	0.000
I49.0 Ventricular fibrillation and flutter	0.002	0.998	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.998	0.002
C71.7 Brain stem	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
C71.4 Occipital lobe	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
I49.4 Other and unspecified premature depolarisation	0.002	0.998	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
N41.8 Other inflammatory diseases of prostate	0.002	0.998	0.000
N41.3 Prostatocystitis	0.002	0.998	0.000
N41.2 Abscess of prostate	0.002	0.998	0.000
C18.3 Hepatic flexure	0.000	0.998	0.002
M47.87 Other spondylosis (Lumbosacral region)	0.002	0.998	0.000
E23.7 Disorder of pituitary gland, unspecified	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.002	0.998	0.000
E28 Ovarian dysfunction	0.002	0.998	0.000
Z99.1 Dependence on respirator	0.002	0.998	0.000
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.002	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.002	0.998	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.002	0.998	0.000
N43 Hydrocele and spermatocele	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
I63.9 Cerebral infarction, unspecified	0.002	0.998	0.000
E46 Unspecified protein-energy malnutrition	0.002	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.002	0.998	0.000
E34 Other endocrine disorders	0.002	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.002	0.998	0.000
I49.5 Sick sinus syndrome	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.998	0.002
O47.1 False labour at or after 37 completed weeks of gestation	0.002	0.998	0.000
J69 Pneumonitis due to solids and liquids	0.000	0.998	0.002
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
N42.1 Congestion and haemorrhage of prostate	0.002	0.998	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.998	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
E20-E35 Disorders of other endocrine glands	0.002	0.998	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.002	0.998	0.000
O03.4 Incomplete, without complication	0.000	0.998	0.002
C61 Malignant neoplasm of prostate	0.000	0.998	0.002
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.998	0.002
C22.0 Liver cell carcinoma	0.000	0.998	0.002
N43.4 Spermatocele	0.002	0.998	0.000
N43.2 Other hydrocele	0.002	0.998	0.000
N43.1 Infected hydrocele	0.002	0.998	0.000
N43.0 Encysted hydrocele	0.002	0.998	0.000
Z51.3 Blood transfusion without reported diagnosis	0.000	0.998	0.002
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.998	0.002
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
J10 Influenza due to identified influenza virus	0.002	0.998	0.000
E14.9 Without complications	0.002	0.998	0.000
Z95.0 Presence of cardiac pacemaker	0.002	0.998	0.000
C22.1 Intrahepatic bile duct carcinoma	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.002	0.998	0.000
C15-C26 Malignant neoplasms of digestive organs	0.000	0.998	0.002
M47.86 Other spondylosis (Lumbar region)	0.002	0.998	0.000
M51.2 Other specified intervertebral disk displacement	0.000	0.998	0.002
R20.8 Other and unspecified disturbances of skin sensation	0.002	0.998	0.000
O97 Death from sequelae of direct obstetric causes	0.001	0.998	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.001	0.998	0.000
O95 Obstetric death of unspecified cause	0.001	0.998	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.001	0.998	0.000
B37.1 Pulmonary candidiasis	0.002	0.998	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.998	0.002
E29.1 Testicular hypofunction	0.000	0.998	0.001
I47.2 Ventricular tachycardia	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.001	0.998	0.000
E34.4 Constitutional tall stature	0.001	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.001	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.001	0.998	0.000
E34.0 Carcinoid syndrome	0.001	0.998	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.001	0.998	0.000
C25 Malignant neoplasm of pancreas	0.000	0.998	0.002
B37.7 Candidal septicaemia	0.001	0.998	0.000
C25.0 Head of pancreas	0.000	0.998	0.002
J69.8 Pneumonitis due to other solids and liquids	0.000	0.998	0.001
J69.1 Pneumonitis due to oils and essences	0.000	0.998	0.001
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
K58 Irritable bowel syndrome	0.002	0.998	0.000
E70-E90 Metabolic disorders	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.001	0.998	0.000
E32 Diseases of thymus	0.001	0.998	0.000
E31 Polyglandular dysfunction	0.001	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.001	0.998	0.000
E29 Testicular dysfunction	0.001	0.998	0.001
E26 Hyperaldosteronism	0.001	0.998	0.000
E25 Adrenogenital disorders	0.001	0.998	0.000
E20 Hypoparathyroidism	0.001	0.998	0.000
N42 Other disorders of prostate	0.002	0.998	0.000
C22.7 Other specified carcinomas of liver	0.000	0.998	0.001
C22.4 Other sarcomas of liver	0.000	0.998	0.001
C22.3 Angiosarcoma of liver	0.000	0.998	0.001
C22.2 Hepatoblastoma	0.000	0.998	0.001
E88.3 Tumour lysis syndrome	0.001	0.998	0.000
N42.0 Calculus of prostate	0.001	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.000	0.998	0.001
I72.8 Aneurysm of other specified arteries	0.001	0.998	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.001	0.998	0.000
E24 Cushing's syndrome	0.001	0.998	0.000
B37 Candidiasis	0.002	0.998	0.000
E88 Other metabolic disorders	0.001	0.998	0.000
B37.2 Candidiasis of skin and nail	0.001	0.998	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.998	0.001
E80.4 Gilbert's syndrome	0.000	0.999	0.001
K90.0 Coeliac disease	0.001	0.999	0.000
O96.9 Death from unspecified obstetric cause	0.001	0.999	0.000
O96.1 Death from indirect obstetric cause	0.001	0.999	0.000
O96.0 Death from direct obstetric cause	0.001	0.999	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.001	0.999	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.001	0.999	0.000
O97.0 Death from sequelae of direct obstetric cause	0.001	0.999	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.999	0.001
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.001	0.999	0.000
N42.2 Atrophy of prostate	0.001	0.999	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.001	0.999	0.000
I72 Other aneurysm	0.001	0.999	0.000
C22.9 Liver, unspecified	0.000	0.999	0.001
C25.8 Overlapping lesion of pancreas	0.000	0.999	0.001
C25.7 Other parts of pancreas	0.000	0.999	0.001
C25.4 Endocrine pancreas	0.000	0.999	0.001
C25.3 Pancreatic duct	0.000	0.999	0.001
C25.2 Tail of pancreas	0.000	0.999	0.001
C25.1 Body of pancreas	0.000	0.999	0.001
S42.10 Fracture of scapula (closed)	0.001	0.999	0.000
E20.9 Hypoparathyroidism, unspecified	0.001	0.999	0.000
E20.8 Other hypoparathyroidism	0.001	0.999	0.000
E20.1 Pseudohypoparathyroidism	0.001	0.999	0.000
E20.0 Idiopathic hypoparathyroidism	0.001	0.999	0.000
E25.9 Adrenogenital disorder, unspecified	0.001	0.999	0.000
E25.8 Other adrenogenital disorders	0.001	0.999	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.001	0.999	0.000
E26.9 Hyperaldosteronism, unspecified	0.001	0.999	0.000
E26.8 Other hyperaldosteronism	0.001	0.999	0.000
E26.1 Secondary hyperaldosteronism	0.001	0.999	0.000
E26.0 Primary hyperaldosteronism	0.001	0.999	0.000
E30.9 Disorder of puberty, unspecified	0.001	0.999	0.000
E30.8 Other disorders of puberty	0.001	0.999	0.000
E30.1 Precocious puberty	0.001	0.999	0.000
E30.0 Delayed puberty	0.001	0.999	0.000
E31.9 Polyglandular dysfunction, unspecified	0.001	0.999	0.000
E31.8 Other polyglandular dysfunction	0.001	0.999	0.000
E31.1 Polyglandular hyperfunction	0.001	0.999	0.000
E31.0 Autoimmune polyglandular failure	0.001	0.999	0.000
E32.9 Disease of thymus, unspecified	0.001	0.999	0.000
E32.8 Other diseases of thymus	0.001	0.999	0.000
E32.1 Abscess of thymus	0.001	0.999	0.000
E32.0 Persistent hyperplasia of thymus	0.001	0.999	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.001	0.999	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.001	0.999	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.001	0.999	0.000
I37.1 Pulmonary valve insufficiency	0.001	0.999	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.999	0.001
E84 Cystic fibrosis	0.001	0.999	0.000
E79 Disorders of purine and pyrimidine metabolism	0.001	0.999	0.000
E77 Disorders of glycoprotein metabolism	0.001	0.999	0.000
E76 Disorders of glycosaminoglycan metabolism	0.001	0.999	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.001	0.999	0.000
E74 Other disorders of carbohydrate metabolism	0.001	0.999	0.000
E72 Other disorders of amino-acid metabolism	0.001	0.999	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.001	0.999	0.000
E70 Disorders of aromatic amino-acid metabolism	0.001	0.999	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.001	0.999	0.000
I47 Paroxysmal tachycardia	0.001	0.999	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.001	0.999	0.000
D86.9 Sarcoidosis, unspecified	0.001	0.999	0.000
E29.9 Testicular dysfunction, unspecified	0.001	0.999	0.001
E29.8 Other testicular dysfunction	0.001	0.999	0.001
E29.0 Testicular hyperfunction	0.001	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations