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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2233955
log Bayes Factor = 64.9269
Chromosome 6   position 31,081,251  (GRCh37) Explore rs2233955 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.012 0.988
L40 Psoriasis
0.000 0.025 0.975
L40.5 Arthropathic psoriasis
0.000 0.036 0.964
L40.0 Psoriasis vulgaris
0.000 0.117 0.883
L40.8 Other psoriasis
0.000 0.290 0.710
L40.4 Guttate psoriasis
0.000 0.301 0.699
L40.3 Pustulosis palmaris et plantaris
0.000 0.301 0.699
L40.2 Acrodermatitis continua
0.000 0.301 0.699
L40.1 Generalised pustular psoriasis
0.000 0.301 0.699
K90 Intestinal malabsorption
0.000 0.307 0.693
K90.9 Intestinal malabsorption, unspecified
0.000 0.391 0.609
E83.1 Disorders of iron metabolism
0.000 0.409 0.591
K90.8 Other intestinal malabsorption
0.000 0.471 0.529
K90.3 Pancreatic steatorrhoea
0.000 0.503 0.497
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.503 0.497
K90.1 Tropical sprue
0.000 0.503 0.497
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.507 0.493
R31 Unspecified haematuria
0.462 0.538 0.000
E03 Other hypothyroidism
0.331 0.664 0.006
L40-L45 Papulosquamous disorders
0.000 0.756 0.244
E03.5 Myxoedema coma
0.237 0.759 0.004
E03.4 Atrophy of thyroid (acquired)
0.237 0.759 0.004
E03.3 Postinfectious hypothyroidism
0.237 0.759 0.004
E03.1 Congenital hypothyroidism without goitre
0.237 0.759 0.004
E03.0 Congenital hypothyroidism with diffuse goitre
0.237 0.759 0.004
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.207 0.789 0.005
C71.9 Brain, unspecified
0.203 0.797 0.000
C71 Malignant neoplasm of brain
0.201 0.799 0.000
E03.8 Other specified hypothyroidism
0.188 0.808 0.005
C71.0 Cerebrum, except lobes and ventricles
0.188 0.812 0.000
C71.2 Temporal lobe
0.179 0.821 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.823 0.177
L44 Other papulosquamous disorders
0.000 0.825 0.175
L41 Parapsoriasis
0.000 0.825 0.175
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.825 0.175
D86 Sarcoidosis
0.000 0.827 0.173
L42 Pityriasis rosea
0.000 0.833 0.167
C71.3 Parietal lobe
0.167 0.833 0.000
C71.4 Occipital lobe
0.165 0.835 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.845 0.155
D86.0 Sarcoidosis of lung
0.000 0.847 0.153
C71.8 Overlapping lesion of brain
0.150 0.850 0.000
C71.1 Frontal lobe
0.149 0.851 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.855 0.145
C71.7 Brain stem
0.145 0.855 0.000
C71.6 Cerebellum
0.145 0.855 0.000
C71.5 Cerebral ventricle
0.145 0.855 0.000
D86.3 Sarcoidosis of skin
0.000 0.868 0.132
L41.9 Parapsoriasis, unspecified
0.000 0.874 0.126
L41.8 Other parapsoriasis
0.000 0.874 0.126
L41.5 Retiform parapsoriasis
0.000 0.874 0.126
L41.4 Large plaque parapsoriasis
0.000 0.874 0.126
L41.3 Small plaque parapsoriasis
0.000 0.874 0.126
L41.2 Lymphomatoid papulosis
0.000 0.874 0.126
L41.1 Pityriasis lichenoides chronica
0.000 0.874 0.126
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.874 0.126
L44.9 Papulosquamous disorder, unspecified
0.000 0.874 0.126
L44.8 Other specified papulosquamous disorders
0.000 0.874 0.126
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.874 0.126
L44.3 Lichen ruber moniliformis
0.000 0.874 0.126
L44.2 Lichen striatus
0.000 0.874 0.126
L44.1 Lichen nitidus
0.000 0.874 0.126
L44.0 Pityriasis rubra pilaris
0.000 0.874 0.126
D80-D89 Certain disorders involving the immune mechanism
0.000 0.876 0.124
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.877 0.123
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.119 0.881 0.000
L43 Lichen planus
0.000 0.889 0.111
D75 Other diseases of blood and blood-forming organs
0.000 0.891 0.109
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.893 0.107
D75.1 Secondary polycythaemia
0.000 0.894 0.106
E00-E07 Disorders of thyroid gland
0.093 0.897 0.010
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.899 0.101
C69 Malignant neoplasm of eye and adnexa
0.101 0.899 0.000
M51.2 Other specified intervertebral disk displacement
0.000 0.902 0.098
D80 Immunodeficiency with predominantly antibody defects
0.000 0.903 0.097
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.903 0.097
D73 Diseases of spleen
0.000 0.906 0.094
D72 Other disorders of white blood cells
0.000 0.906 0.094
K90-K93 Other diseases of the digestive system
0.000 0.906 0.094
D83 Common variable immunodeficiency
0.000 0.910 0.090
D82 Immunodeficiency associated with other major defects
0.000 0.911 0.089
D81 Combined immunodeficiencies
0.000 0.911 0.089
C70 Malignant neoplasm of meninges
0.089 0.911 0.000
D75.2 Essential thrombocytosis
0.000 0.911 0.089
D72.8 Other specified disorders of white blood cells
0.000 0.913 0.087
E07 Other disorders of thyroid
0.082 0.913 0.005
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.085 0.914 0.000
D75.0 Familial erythrocytosis
0.000 0.915 0.085
D73.0 Hyposplenism
0.000 0.916 0.084
C69.9 Eye, unspecified
0.082 0.918 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.920 0.080
L43.3 Subacute (active) lichen planus
0.000 0.920 0.079
L43.2 Lichenoid drug reaction
0.000 0.920 0.079
L43.1 Bullous lichen planus
0.000 0.920 0.079
L43.0 Hypertrophic lichen planus
0.000 0.920 0.079
E02 Subclinical iodine-deficiency hypothyroidism
0.073 0.921 0.006
C69.0 Conjunctiva
0.078 0.922 0.000
E07.9 Disorder of thyroid, unspecified
0.077 0.923 0.001
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.923 0.077
D74 Methaemoglobinaemia
0.000 0.923 0.077
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.923 0.077
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.923 0.077
E06 Thyroiditis
0.070 0.925 0.004
C69.3 Choroid
0.075 0.925 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.067 0.926 0.007
E00 Congenital iodine-deficiency syndrome
0.067 0.926 0.007
D50-D53 Nutritional anaemias
0.000 0.927 0.073
D73.8 Other diseases of spleen
0.000 0.927 0.072
E83 Disorders of mineral metabolism
0.000 0.927 0.072
D55-D59 Haemolytic anaemias
0.000 0.927 0.072
C69.8 Overlapping lesion of eye and adnexa
0.072 0.928 0.000
C69.6 Orbit
0.072 0.928 0.000
C69.5 Lachrymal gland and duct
0.072 0.928 0.000
C69.4 Ciliary body
0.072 0.928 0.000
C69.2 Retina
0.072 0.928 0.000
C69.1 Cornea
0.072 0.928 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.929 0.071
D84 Other immunodeficiencies
0.000 0.929 0.071
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.929 0.071
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.930 0.070
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.930 0.070
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.930 0.070
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.930 0.070
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.930 0.070
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.930 0.070
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.930 0.070
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.930 0.070
E16.2 Hypoglycaemia, unspecified
0.000 0.931 0.069
L43.8 Other lichen planus
0.000 0.931 0.069
D73.4 Cyst of spleen
0.000 0.931 0.069
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.932 0.068
D73.9 Disease of spleen, unspecified
0.000 0.932 0.068
D73.3 Abscess of spleen
0.000 0.932 0.068
D73.2 Chronic congestive splenomegaly
0.000 0.932 0.068
D73.1 Hypersplenism
0.000 0.932 0.068
M51 Other intervertebral disk disorders
0.000 0.932 0.068
C70.0 Cerebral meninges
0.067 0.932 0.000
D72.9 Disorder of white blood cells, unspecified
0.000 0.933 0.067
D72.0 Genetic anomalies of leukocytes
0.000 0.933 0.067
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.933 0.067
D83.9 Common variable immunodeficiency, unspecified
0.000 0.935 0.065
D83.8 Other common variable immunodeficiencies
0.000 0.935 0.065
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.935 0.065
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.935 0.065
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.935 0.065
D81.9 Combined immunodeficiency, unspecified
0.000 0.936 0.064
D81.8 Other combined immunodeficiencies
0.000 0.936 0.064
D81.7 Major histocompatibility complex class II deficiency
0.000 0.936 0.064
D81.6 Major histocompatibility complex class I deficiency
0.000 0.936 0.064
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.936 0.064
D81.4 Nezelof's syndrome
0.000 0.936 0.064
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.936 0.064
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.936 0.064
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.936 0.064
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.936 0.064
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.936 0.064
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.936 0.064
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.936 0.064
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.936 0.064
D82.2 Immunodeficiency with short-limbed stature
0.000 0.936 0.064
D82.1 Di George's syndrome
0.000 0.936 0.064
D82.0 Wiskott-Aldrich syndrome
0.000 0.936 0.064
D51 Vitamin B12 deficiency anaemia
0.000 0.936 0.064
C70.9 Meninges, unspecified
0.064 0.936 0.000
C70.1 Spinal meninges
0.064 0.936 0.000
D73.5 Infarction of spleen
0.000 0.937 0.062
E07.1 Dyshormogenetic goitre
0.059 0.938 0.003
E07.0 Hypersecretion of calcitonin
0.059 0.938 0.003
D70 Agranulocytosis
0.000 0.938 0.062
C72.9 Central nervous system, unspecified
0.061 0.938 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.061 0.938 0.000
C72.5 Other and unspecified cranial nerves
0.061 0.938 0.000
C72.4 Acoustic nerve
0.061 0.938 0.000
C72.3 Optic nerve
0.061 0.938 0.000
C72.2 Olfactory nerve
0.061 0.938 0.000
C72.1 Cauda equina
0.061 0.938 0.000
C72.0 Spinal cord
0.061 0.938 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.939 0.061
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.940 0.059
D59 Acquired haemolytic anaemia
0.000 0.940 0.059
M51.8 Other specified intervertebral disk disorders
0.000 0.941 0.059
E06.1 Subacute thyroiditis
0.056 0.941 0.003
D53 Other nutritional anaemias
0.000 0.941 0.059
E06.5 Other chronic thyroiditis
0.056 0.941 0.003
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.943 0.057
D89.3 Immune reconstitution syndrome
0.000 0.943 0.057
D89.1 Cryoglobulinaemia
0.000 0.943 0.057
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.943 0.057
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.943 0.057
D72.1 Eosinophilia
0.000 0.943 0.056
D74.9 Methaemoglobinaemia, unspecified
0.000 0.945 0.055
D74.8 Other methaemoglobinaemias
0.000 0.945 0.055
D74.0 Congenital methaemoglobinaemia
0.000 0.945 0.055
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.945 0.055
E07.8 Other specified disorders of thyroid
0.051 0.945 0.004
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.946 0.054
E06.4 Drug-induced thyroiditis
0.051 0.946 0.003
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.051 0.946 0.003
E06.0 Acute thyroiditis
0.051 0.946 0.003
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.048 0.947 0.005
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.048 0.947 0.005
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.048 0.947 0.005
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.048 0.947 0.005
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.048 0.947 0.005
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.048 0.947 0.005
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.048 0.947 0.005
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.048 0.947 0.005
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.947 0.053
D57 Sickle-cell disorders
0.000 0.948 0.052
D55 Anaemia due to enzyme disorders
0.000 0.948 0.052
E06.3 Autoimmune thyroiditis
0.050 0.948 0.002
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.948 0.052
E83.8 Other disorders of mineral metabolism
0.000 0.948 0.052
E83.2 Disorders of zinc metabolism
0.000 0.948 0.052
E83.0 Disorders of copper metabolism
0.000 0.948 0.052
M51.4 Schmorl's nodes
0.000 0.948 0.052
D58 Other hereditary haemolytic anaemias
0.000 0.948 0.052
D84.8 Other specified immunodeficiencies
0.000 0.949 0.051
D84.1 Defects in the complement system
0.000 0.949 0.051
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.949 0.051
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.950 0.050
Chapter IV Endocrine, nutritional and metabolic diseases
0.001 0.950 0.049
M51.9 Intervertebral disk disorder, unspecified
0.000 0.951 0.049
D53.9 Nutritional anaemia, unspecified
0.000 0.951 0.049
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.000 0.951 0.049
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.951 0.049
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.951 0.049
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.951 0.049
M51.3 Other specified intervertebral disk degeneration
0.000 0.951 0.049
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.000 0.951 0.049
E10-E14 Diabetes mellitus
0.000 0.951 0.049
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.951 0.048
K93.1 Megacolon in Chagas' disease
0.000 0.951 0.048
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.951 0.048
E70-E90 Metabolic disorders
0.000 0.952 0.048
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.954 0.046
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.954 0.046
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.954 0.046
D51.2 Transcobalamin II deficiency
0.000 0.954 0.046
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.954 0.046
E88 Other metabolic disorders
0.000 0.954 0.046
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.954 0.046
E50-E64 Other nutritional deficiencies
0.000 0.956 0.044
E16.1 Other hypoglycaemia
0.000 0.956 0.044
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.956 0.044
K91.3 Postoperative intestinal obstruction
0.000 0.956 0.044
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.956 0.044
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.956 0.044
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.956 0.044
E16.4 Abnormal secretion of gastrin
0.000 0.956 0.044
E16.3 Increased secretion of glucagon
0.000 0.956 0.044
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.956 0.044
E06.9 Thyroiditis, unspecified
0.040 0.956 0.004
D59.1 Other autoimmune haemolytic anaemias
0.000 0.956 0.044
E11 Non-insulin-dependent diabetes mellitus
0.000 0.956 0.044
E10 Insulin-dependent diabetes mellitus
0.000 0.956 0.044
E11.4 With neurological complications
0.000 0.957 0.043
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.957 0.043
D59.8 Other acquired haemolytic anaemias
0.000 0.957 0.043
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.957 0.043
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.957 0.043
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.957 0.043
D59.3 Haemolytic-uraemic syndrome
0.000 0.957 0.043
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.957 0.043
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.957 0.043
D53.8 Other specified nutritional anaemias
0.000 0.957 0.042
D53.2 Scorbutic anaemia
0.000 0.957 0.042
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.957 0.042
D53.0 Protein deficiency anaemia
0.000 0.957 0.042
E55 Vitamin D deficiency
0.000 0.958 0.042
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.958 0.042
E55.9 Vitamin D deficiency, unspecified
0.000 0.959 0.041
E85 Amyloidosis
0.000 0.959 0.041
D56 Thalassaemia
0.000 0.959 0.041
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.959 0.041
D76.3 Other histiocytosis syndromes
0.000 0.960 0.040
E13 Other specified diabetes mellitus
0.000 0.960 0.040
E10.3 With ophthalmic complications
0.000 0.961 0.039
K91.1 Postgastric surgery syndromes
0.000 0.961 0.039
L43.9 Lichen planus, unspecified
0.000 0.961 0.039
E15 Nondiabetic hypoglycaemic coma
0.000 0.961 0.039
E11.5 With peripheral circulatory complications
0.000 0.962 0.038
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.962 0.037
D55.8 Other anaemias due to enzyme disorders
0.000 0.962 0.037
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.962 0.037
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.962 0.037
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.962 0.037
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.962 0.037
D57.8 Other sickle-cell disorders
0.000 0.962 0.037
D57.3 Sickle-cell trait
0.000 0.962 0.037
D57.2 Double heterozygous sickling disorders
0.000 0.962 0.037
D57.1 Sickle-cell anaemia without crisis
0.000 0.962 0.037
D57.0 Sickle-cell anaemia with crisis
0.000 0.962 0.037
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.962 0.037
D58.2 Other haemoglobinopathies
0.000 0.962 0.037
D58.1 Hereditary elliptocytosis
0.000 0.962 0.037
K91.5 Postcholecystectomy syndrome
0.000 0.962 0.038
D52 Folate deficiency anaemia
0.000 0.963 0.037
E11.8 With unspecified complications
0.000 0.965 0.035
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified
0.000 0.965 0.035
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region
0.000 0.965 0.035
M51.37 Other intervertebral disc degeneration, lumbosacral region
0.000 0.965 0.035
E10.2 With renal complications
0.000 0.965 0.035
E12 Malnutrition-related diabetes mellitus
0.000 0.965 0.035
E79 Disorders of purine and pyrimidine metabolism
0.000 0.965 0.035
E77 Disorders of glycoprotein metabolism
0.000 0.965 0.035
E76 Disorders of glycosaminoglycan metabolism
0.000 0.965 0.035
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.965 0.035
E72 Other disorders of amino-acid metabolism
0.000 0.965 0.035
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.965 0.035
E70 Disorders of aromatic amino-acid metabolism
0.000 0.965 0.035
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.965 0.035
E14 Unspecified diabetes mellitus
0.000 0.965 0.035
E84 Cystic fibrosis
0.000 0.965 0.035
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.965 0.035
E53 Deficiency of other B group vitamins
0.000 0.966 0.034
E85.4 Organ-limited amyloidosis
0.000 0.966 0.034
E11.6 With other specified complications
0.000 0.966 0.034
E04 Other non-toxic goitre
0.032 0.966 0.001
E13.9 Without complications
0.000 0.966 0.034
E88.9 Metabolic disorder, unspecified
0.000 0.967 0.033
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.967 0.033
D84.9 Immunodeficiency, unspecified
0.001 0.967 0.032
E10.0 With coma
0.000 0.967 0.033
E10.9 Without complications
0.000 0.967 0.033
E88.3 Tumour lysis syndrome
0.000 0.967 0.033
E85.9 Amyloidosis, unspecified
0.000 0.967 0.033
E88.2 Lipomatosis, not elsewhere classified
0.000 0.967 0.033
D50 Iron deficiency anaemia
0.000 0.967 0.033
E11.1 With ketoacidosis
0.000 0.968 0.032
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.968 0.032
E63 Other nutritional deficiencies
0.000 0.968 0.032
E56 Other vitamin deficiencies
0.000 0.968 0.032
E51 Thiamine deficiency
0.000 0.968 0.032
E50 Vitamin A deficiency
0.000 0.968 0.032
E60 Dietary zinc deficiency
0.000 0.968 0.032
E59 Dietary selenium deficiency
0.000 0.968 0.032
E58 Dietary calcium deficiency
0.000 0.968 0.032
E54 Ascorbic acid deficiency
0.000 0.968 0.032
E52 Niacin deficiency [pellagra]
0.000 0.968 0.032
E65-E68 Obesity and other hyperalimentation
0.000 0.968 0.032
E10.8 With unspecified complications
0.000 0.968 0.032
E74 Other disorders of carbohydrate metabolism
0.000 0.968 0.032
E88.8 Other specified metabolic disorders
0.000 0.968 0.032
E11.7 With multiple complications
0.000 0.968 0.032
E10.7 With multiple complications
0.000 0.969 0.031
D58.0 Hereditary spherocytosis
0.000 0.969 0.031
E10.6 With other specified complications
0.000 0.969 0.031
E55.0 Rickets, active
0.000 0.969 0.030
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.969 0.030
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.970 0.030
E10.1 With ketoacidosis
0.000 0.970 0.030
E11.2 With renal complications
0.000 0.970 0.030
I26 Pulmonary embolism
0.000 0.970 0.030
E85.8 Other amyloidosis
0.000 0.970 0.030
E85.3 Secondary systemic amyloidosis
0.000 0.970 0.030
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.970 0.030
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.970 0.030
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.970 0.030
D56.9 Thalassaemia, unspecified
0.000 0.970 0.029
D56.8 Other thalassaemias
0.000 0.970 0.029
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.970 0.029
D56.2 Delta-beta thalassaemia
0.000 0.970 0.029
D56.0 Alpha thalassaemia
0.000 0.970 0.029
D50.8 Other iron deficiency anaemias
0.000 0.971 0.029
E73 Lactose intolerance
0.000 0.971 0.029
E10.4 With neurological complications
0.000 0.971 0.029
E13.8 With unspecified complications
0.000 0.971 0.029
E13.7 With multiple complications
0.000 0.971 0.029
E13.6 With other specified complications
0.000 0.971 0.029
E13.5 With peripheral circulatory complications
0.000 0.971 0.029
E13.4 With neurological complications
0.000 0.971 0.029
E13.3 With ophthalmic complications
0.000 0.971 0.029
E13.2 With renal complications
0.000 0.971 0.029
E13.1 With ketoacidosis
0.000 0.971 0.029
E13.0 With coma
0.000 0.971 0.029
E14.4 With neurological complications
0.000 0.971 0.029
E10.5 With peripheral circulatory complications
0.000 0.971 0.029
E83.5 Disorders of calcium metabolism
0.000 0.972 0.028
I27.9 Pulmonary heart disease, unspecified
0.000 0.973 0.027
D60-D64 Aplastic and other anaemias
0.000 0.973 0.027
E14.8 With unspecified complications
0.000 0.973 0.027
E11.0 With coma
0.000 0.973 0.027
I27 Other pulmonary heart diseases
0.000 0.973 0.027
D52.8 Other folate deficiency anaemias
0.000 0.973 0.026
D52.1 Drug-induced folate deficiency anaemia
0.000 0.973 0.026
D52.0 Dietary folate deficiency anaemia
0.000 0.973 0.026
D56.3 Thalassaemia trait
0.000 0.973 0.026
E40-E46 Malnutrition
0.001 0.973 0.026
E53.8 Deficiency of other specified B group vitamins
0.000 0.973 0.027
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.974 0.026
E05 Thyrotoxicosis [hyperthyroidism]
0.017 0.974 0.008
E11.3 With ophthalmic complications
0.000 0.974 0.026
E12.9 Without complications
0.000 0.975 0.025
E12.8 With unspecified complications
0.000 0.975 0.025
E12.7 With multiple complications
0.000 0.975 0.025
E12.6 With other specified complications
0.000 0.975 0.025
E12.5 With peripheral circulatory complications
0.000 0.975 0.025
E12.4 With neurological complications
0.000 0.975 0.025
E12.3 With ophthalmic complications
0.000 0.975 0.025
E12.2 With renal complications
0.000 0.975 0.025
E12.1 With ketoacidosis
0.000 0.975 0.025
E12.0 With coma
0.000 0.975 0.025
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.975 0.025
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.975 0.025
E70.3 Albinism
0.000 0.975 0.025
E70.2 Disorders of tyrosine metabolism
0.000 0.975 0.025
E70.1 Other hyperphenylalaninaemias
0.000 0.975 0.025
E70.0 Classical phenylketonuria
0.000 0.975 0.025
E71.3 Disorders of fatty-acid metabolism
0.000 0.975 0.025
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.975 0.025
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.975 0.025
E71.0 Maple-syrup-urine disease
0.000 0.975 0.025
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.975 0.025
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.975 0.025
E72.5 Disorders of glycine metabolism
0.000 0.975 0.025
E72.4 Disorders of ornithine metabolism
0.000 0.975 0.025
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.975 0.025
E72.2 Disorders of urea cycle metabolism
0.000 0.975 0.025
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.975 0.025
E72.0 Disorders of amino-acid transport
0.000 0.975 0.025
E75.6 Lipid storage disorder, unspecified
0.000 0.975 0.025
E75.5 Other lipid storage disorders
0.000 0.975 0.025
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.975 0.025
E75.3 Sphingolipidosis, unspecified
0.000 0.975 0.025
E75.2 Other sphingolipidosis
0.000 0.975 0.025
E75.1 Other gangliosidosis
0.000 0.975 0.025
E75.0 GM2 gangliosidosis
0.000 0.975 0.025
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.975 0.025
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.975 0.025
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.975 0.025
E76.2 Other mucopolysaccharidoses
0.000 0.975 0.025
E76.1 Mucopolysaccharidosis, type II
0.000 0.975 0.025
E76.0 Mucopolysaccharidosis, type I
0.000 0.975 0.025
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.975 0.025
E77.8 Other disorders of glycoprotein metabolism
0.000 0.975 0.025
E77.1 Defects in glycoprotein degradation
0.000 0.975 0.025
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.975 0.025
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.975 0.025
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.975 0.025
E79.1 Lesch-Nyhan syndrome
0.000 0.975 0.025
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.975 0.025
E14.7 With multiple complications
0.000 0.975 0.025
E14.2 Withrenal complications
0.000 0.975 0.025
E14.0 With coma
0.000 0.975 0.025
E84.8 Cystic fibrosis with other manifestations
0.000 0.975 0.025
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.975 0.025
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.975 0.025
E14.6 With other specified complications
0.000 0.975 0.025
E84.9 Cystic fibrosis, unspecified
0.000 0.975 0.025
E14.1 With ketoacidosis
0.000 0.975 0.025
E53.9 Vitamin B deficiency, unspecified
0.000 0.975 0.025
E53.1 Pyridoxine deficiency
0.000 0.975 0.024
E53.0 Riboflavin deficiency
0.000 0.975 0.024
E04.8 Other specified non-toxic goitre
0.023 0.976 0.001
E61 Deficiency of other nutrient elements
0.000 0.976 0.024
E14.3 With ophthalmic complications
0.000 0.976 0.024
E14.5 With peripheral circulatory complications
0.000 0.976 0.024
D50.1 Sideropenic dysphagia
0.000 0.976 0.023
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.976 0.023
E83.3 Disorders of phosphorus metabolism
0.001 0.977 0.023
E50.9 Vitamin A deficiency, unspecified
0.000 0.977 0.023
E50.8 Other manifestations of vitamin A deficiency
0.000 0.977 0.023
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.977 0.023
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.977 0.023
E50.5 Vitamin A deficiency with night blindness
0.000 0.977 0.023
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.977 0.023
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.977 0.023
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.977 0.023
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.977 0.023
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.977 0.023
E51.9 Thiamine deficiency, unspecified
0.000 0.977 0.023
E51.8 Other manifestations of thiamine deficiency
0.000 0.977 0.023
E51.2 Wernicke's encephalopathy
0.000 0.977 0.023
E51.1 Beriberi
0.000 0.977 0.023
E56.9 Vitamin deficiency, unspecified
0.000 0.977 0.023
E56.8 Deficiency of other vitamins
0.000 0.977 0.023
E56.1 Deficiency of vitamin K
0.000 0.977 0.023
E56.0 Deficiency of vitamin E
0.000 0.977 0.023
E63.9 Nutritional deficiency, unspecified
0.000 0.977 0.023
E63.8 Other specified nutritional deficiencies
0.000 0.977 0.023
E63.1 Imbalance of constituents of food intake
0.000 0.977 0.023
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.977 0.023
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.977 0.023
E64.8 Sequelae of other nutritional deficiencies
0.000 0.977 0.023
E64.3 Sequelae of rickets
0.000 0.977 0.023
E64.2 Sequelae of vitamin C deficiency
0.000 0.977 0.023
E64.1 Sequelae of vitamin A deficiency
0.000 0.977 0.023
E64.0 Sequelae of protein-energy malnutrition
0.000 0.977 0.023
E04.1 Non-toxic single thyroid nodule
0.023 0.977 0.000
E67 Other hyperalimentation
0.000 0.977 0.023
E68 Sequelae of hyperalimentation
0.000 0.977 0.023
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.977 0.023
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.977 0.023
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.977 0.023
E74.2 Disorders of galactose metabolism
0.000 0.977 0.023
E74.1 Disorders of fructose metabolism
0.000 0.977 0.023
E74.0 Glycogen storage disease
0.000 0.977 0.023

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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