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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2236313
log Bayes Factor = 11.6047
Chromosome 6   position 167,360,389  (GRCh37) Explore rs2236313 on Ensembl!
Variant rs2236313 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.005 0.995
E03.8 Other specified hypothyroidism
0.000 0.109 0.891
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.165 0.835
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.172 0.828
E03.1 Congenital hypothyroidism without goitre
0.000 0.245 0.755
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E07 Other disorders of thyroid
0.000 0.331 0.669
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.338 0.662
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.351 0.648
E05.8 Other thyrotoxicosis
0.000 0.368 0.632
E07.9 Disorder of thyroid, unspecified
0.000 0.454 0.546
E06 Thyroiditis
0.000 0.470 0.530
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E07.1 Dyshormogenetic goitre
0.000 0.520 0.480
E07.0 Hypersecretion of calcitonin
0.000 0.520 0.480
E06.1 Subacute thyroiditis
0.000 0.591 0.409
E06.5 Other chronic thyroiditis
0.000 0.615 0.385
E06.4 Drug-induced thyroiditis
0.000 0.620 0.380
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.620 0.380
E06.0 Acute thyroiditis
0.000 0.620 0.380
E06.9 Thyroiditis, unspecified
0.000 0.678 0.322
E07.8 Other specified disorders of thyroid
0.001 0.694 0.305
E06.3 Autoimmune thyroiditis
0.000 0.777 0.222
E04 Other non-toxic goitre
0.000 0.809 0.191
E04.8 Other specified non-toxic goitre
0.000 0.863 0.137
E04.0 Non-toxic diffuse goitre
0.000 0.868 0.131
E04.9 Non-toxic goitre, unspecified
0.000 0.896 0.104
E04.2 Non-toxic multinodular goitre
0.000 0.922 0.078
C44.3 Skin of other and unspecified parts of face
0.040 0.960 0.000
C44.6 Skin of upper limb, including shoulder
0.037 0.963 0.000
C44.5 Skin of trunk
0.034 0.966 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.966 0.034
C44 Other malignant neoplasms of skin
0.033 0.967 0.000
C44.2 Skin of ear and external auricular canal
0.031 0.969 0.000
L43.9 Lichen planus, unspecified
0.000 0.970 0.030
C44.8 Overlapping lesion of skin
0.024 0.976 0.000
L43 Lichen planus
0.000 0.981 0.019
C44.9 Malignant neoplasm of skin, unspecified
0.017 0.983 0.000
L43.8 Other lichen planus
0.000 0.983 0.017
Z04.8 Examination and observation for other specified reasons
0.000 0.985 0.015
F31.0 Bipolar affective disorder, current episode hypomanic
0.014 0.986 0.000
L43.3 Subacute (active) lichen planus
0.000 0.986 0.014
L43.2 Lichenoid drug reaction
0.000 0.986 0.014
L43.1 Bullous lichen planus
0.000 0.986 0.014
L43.0 Hypertrophic lichen planus
0.000 0.986 0.014
F31 Bipolar affective disorder
0.013 0.987 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.013 0.987 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.012 0.988 0.000
F31.7 Bipolar affective disorder, currently in remission
0.012 0.988 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.012 0.988 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.011 0.989 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.989 0.011
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.011 0.989 0.000
S20.2 Contusion of thorax
0.011 0.989 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.010 0.990 0.000
F31.8 Other bipolar affective disorders
0.009 0.990 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.009 0.991 0.000
F31.9 Bipolar affective disorder, unspecified
0.008 0.992 0.000
S83.2 Tear of meniscus, current
0.000 0.992 0.008
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.992 0.008
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.008 0.992 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.007 0.993 0.000
C48.1 Specified parts of peritoneum
0.007 0.993 0.000
C48.0 Retroperitoneum
0.007 0.993 0.000
T79.6 Traumatic ischaemia of muscle
0.000 0.993 0.007
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.007 0.993 0.000
E40-E46 Malnutrition
0.000 0.993 0.007
F31.6 Bipolar affective disorder, current episode mixed
0.006 0.993 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.007 0.993 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.000 0.993 0.007
E23.0 Hypopituitarism
0.000 0.994 0.006
G12.2 Motor neuron disease
0.000 0.994 0.006
E50-E64 Other nutritional deficiencies
0.000 0.994 0.006
C45.9 Mesothelioma, unspecified
0.006 0.994 0.000
C49.3 Connective and soft tissue of thorax
0.006 0.994 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.000 0.994 0.006
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.000 0.994 0.006
C48.2 Peritoneum, unspecified
0.006 0.994 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.994 0.006
C45 Mesothelioma
0.006 0.994 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.000 0.994 0.006
C44.4 Skin of scalp and neck
0.006 0.994 0.000
K70.3 Alcoholic cirrhosis of liver
0.006 0.994 0.000
C49.0 Connective and soft tissue of head, face and neck
0.006 0.994 0.000
C49.5 Connective and soft tissue of pelvis
0.006 0.994 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.994 0.006
C49.4 Connective and soft tissue of abdomen
0.006 0.994 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.994 0.006
C49.9 Connective and soft tissue, unspecified
0.006 0.994 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.006 0.994 0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.006 0.994 0.000
S83.3 Tear of articular cartilage of knee, current
0.000 0.994 0.006
C49.8 Overlapping lesion of connective and soft tissue
0.005 0.994 0.000
E89.0 Postprocedural hypothyroidism
0.000 0.995 0.005
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.995 0.005
E16 Other disorders of pancreatic internal secretion
0.000 0.995 0.005
E23 Hypofunction and other disorders of pituitary gland
0.000 0.995 0.005
T79.5 Traumatic anuria
0.000 0.995 0.005
T79.8 Other early complications of trauma
0.000 0.995 0.005
E51 Thiamine deficiency
0.000 0.995 0.005
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.005 0.995 0.000
C46 Kaposi's sarcoma
0.005 0.995 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.995 0.005
E45 Retarded development following protein-energy malnutrition
0.000 0.995 0.005
E43 Unspecified severe protein-energy malnutrition
0.000 0.995 0.005
E42 Marasmic kwashiorkor
0.000 0.995 0.005
E41 Nutritional marasmus
0.000 0.995 0.005
E40 Kwashiorkor
0.000 0.995 0.005
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.000 0.995 0.005
C44.7 Skin of lower limb, including hip
0.005 0.995 0.000
E83.1 Disorders of iron metabolism
0.000 0.995 0.005
C44.0 Skin of lip
0.005 0.995 0.000
C49.6 Connective and soft tissue of trunk, unspecified
0.005 0.995 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.995 0.005
C43.5 Malignant melanoma of trunk
0.005 0.995 0.000
E14 Unspecified diabetes mellitus
0.000 0.995 0.005
E61 Deficiency of other nutrient elements
0.000 0.995 0.005
D46 Myelodysplastic syndromes
0.005 0.995 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.995 0.005
E50 Vitamin A deficiency
0.000 0.995 0.005
E60 Dietary zinc deficiency
0.000 0.995 0.005
E59 Dietary selenium deficiency
0.000 0.995 0.005
E58 Dietary calcium deficiency
0.000 0.995 0.005
E54 Ascorbic acid deficiency
0.000 0.995 0.005
E52 Niacin deficiency [pellagra]
0.000 0.995 0.005
E56 Other vitamin deficiencies
0.000 0.995 0.005
E10-E14 Diabetes mellitus
0.000 0.995 0.005
C45.2 Mesothelioma of pericardium
0.005 0.995 0.000
C45.1 Mesothelioma of peritoneum
0.005 0.995 0.000
T79.9 Unspecified early complication of trauma
0.000 0.995 0.005
T79.2 Traumatic secondary and recurrent haemorrhage
0.000 0.995 0.005
T79.1 Fat embolism (traumatic)
0.000 0.995 0.005
T79.0 Air embolism (traumatic)
0.000 0.995 0.005
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.995 0.005
E20-E35 Disorders of other endocrine glands
0.000 0.995 0.005
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.000 0.995 0.005
E14.9 Without complications
0.000 0.995 0.005
E53 Deficiency of other B group vitamins
0.000 0.995 0.004
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.000 0.995 0.004
E63 Other nutritional deficiencies
0.000 0.996 0.004
S83.7 Injury to multiple structures of knee
0.000 0.996 0.004
E14.3 With ophthalmic complications
0.000 0.996 0.004
E89.3 Postprocedural hypopituitarism
0.000 0.996 0.004
S83.1 Dislocation of knee
0.000 0.996 0.004
C43 Malignant melanoma of skin
0.004 0.996 0.000
E51.2 Wernicke's encephalopathy
0.000 0.996 0.004
T79.4 Traumatic shock
0.000 0.996 0.004
E70-E90 Metabolic disorders
0.000 0.996 0.004
E14.4 With neurological complications
0.000 0.996 0.004
C45.7 Mesothelioma of other sites
0.004 0.996 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.996 0.004
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.996 0.004
E16.4 Abnormal secretion of gastrin
0.000 0.996 0.004
E16.3 Increased secretion of glucagon
0.000 0.996 0.004
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.996 0.004
E89.5 Postprocedural testicular hypofunction
0.000 0.996 0.004
K70.9 Alcoholic liver disease, unspecified
0.004 0.996 0.000
E89.1 Postprocedural hypoinsulinaemia
0.000 0.996 0.004
S00.8 Superficial injury of other parts of head
0.000 0.996 0.004
E16.1 Other hypoglycaemia
0.000 0.996 0.004
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.996 0.004
E23.1 Drug-induced hypopituitarism
0.000 0.996 0.004
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.996 0.004
E61.2 Magnesium deficiency
0.000 0.996 0.004
S83.0 Dislocation of patella
0.000 0.996 0.004
E14.1 With ketoacidosis
0.000 0.996 0.004
E51.9 Thiamine deficiency, unspecified
0.000 0.996 0.004
E51.8 Other manifestations of thiamine deficiency
0.000 0.996 0.004
E51.1 Beriberi
0.000 0.996 0.004
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.996 0.004
C46.9 Kaposi's sarcoma, unspecified
0.004 0.996 0.000
C46.8 Kaposi's sarcoma of multiple organs
0.004 0.996 0.000
C46.7 Kaposi's sarcoma of other sites
0.004 0.996 0.000
C46.3 Kaposi's sarcoma of lymph nodes
0.004 0.996 0.000
C46.2 Kaposi's sarcoma of palate
0.004 0.996 0.000
C46.1 Kaposi's sarcoma of soft tissue
0.004 0.996 0.000
C46.0 Kaposi's sarcoma of skin
0.004 0.996 0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.004 0.996 0.000
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.004 0.996 0.000
C47.6 Peripheral nerves of trunk, unspecified
0.004 0.996 0.000
C47.5 Peripheral nerves of pelvis
0.004 0.996 0.000
C47.4 Peripheral nerves of abdomen
0.004 0.996 0.000
C47.3 Peripheral nerves of thorax
0.004 0.996 0.000
C47.2 Peripheral nerves of lower limb, including hip
0.004 0.996 0.000
C47.1 Peripheral nerves of upper limb, including shoulder
0.004 0.996 0.000
C47.0 Peripheral nerves of head, face and neck
0.004 0.996 0.000
C44.1 Skin of eyelid, including canthus
0.004 0.996 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.996 0.004
E44.0 Moderate protein-energy malnutrition
0.000 0.996 0.004
D46.2 Refractory anaemia with excess of blasts
0.004 0.996 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.004 0.996 0.000
D46.4 Refractory anaemia, unspecified
0.004 0.996 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.996 0.004
E23.2 Diabetes insipidus
0.000 0.996 0.004
E14.5 With peripheral circulatory complications
0.000 0.996 0.004
E83 Disorders of mineral metabolism
0.000 0.996 0.004
E14.7 With multiple complications
0.000 0.996 0.004
E14.0 With coma
0.000 0.996 0.004
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
0.000 0.996 0.004
E61.9 Deficiency of nutrient element, unspecified
0.000 0.996 0.004
E61.8 Deficiency of other specified nutrient elements
0.000 0.996 0.004
E61.7 Deficiency of multiple nutrient elements
0.000 0.996 0.004
E61.6 Vanadium deficiency
0.000 0.996 0.004
E61.5 Molybdenum deficiency
0.000 0.996 0.004
E61.4 Chromium deficiency
0.000 0.996 0.004
E61.3 Manganese deficiency
0.000 0.996 0.004
E61.0 Copper deficiency
0.000 0.996 0.004
E74 Other disorders of carbohydrate metabolism
0.000 0.996 0.004
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.004 0.996 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.004 0.996 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.004 0.996 0.000
E14.2 Withrenal complications
0.000 0.996 0.004
E50.9 Vitamin A deficiency, unspecified
0.000 0.996 0.004
E50.8 Other manifestations of vitamin A deficiency
0.000 0.996 0.004
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.996 0.004
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.996 0.004
E50.5 Vitamin A deficiency with night blindness
0.000 0.996 0.004
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.996 0.004
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.996 0.004
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.996 0.004
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.996 0.004
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.996 0.004
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.996 0.004
E64.8 Sequelae of other nutritional deficiencies
0.000 0.996 0.004
E64.3 Sequelae of rickets
0.000 0.996 0.004
E64.2 Sequelae of vitamin C deficiency
0.000 0.996 0.004
E64.1 Sequelae of vitamin A deficiency
0.000 0.996 0.004
E64.0 Sequelae of protein-energy malnutrition
0.000 0.996 0.004
C45.0 Mesothelioma of pleura
0.004 0.996 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.996 0.004
G12 Spinal muscular atrophy and related syndromes
0.000 0.996 0.004
C43.3 Malignant melanoma of other and unspecified parts of face
0.004 0.996 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.996 0.004
E12 Malnutrition-related diabetes mellitus
0.000 0.996 0.004
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.000 0.996 0.004
D46.1 Refractory anaemia with sideroblasts
0.004 0.996 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.996 0.003
E56.8 Deficiency of other vitamins
0.000 0.996 0.003
E56.0 Deficiency of vitamin E
0.000 0.996 0.003
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.996 0.004
E14.6 With other specified complications
0.000 0.996 0.004
E53.8 Deficiency of other specified B group vitamins
0.000 0.996 0.004
C43.9 Malignant melanoma of skin, unspecified
0.004 0.996 0.000
E13 Other specified diabetes mellitus
0.000 0.996 0.004
E25 Adrenogenital disorders
0.000 0.996 0.004
E56.1 Deficiency of vitamin K
0.000 0.996 0.003
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.996 0.003
E32 Diseases of thymus
0.000 0.996 0.003
E30 Disorders of puberty, not elsewhere classified
0.000 0.996 0.003
K70 Alcoholic liver disease
0.004 0.996 0.000
C43.4 Malignant melanoma of scalp and neck
0.003 0.996 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.996 0.004
E88 Other metabolic disorders
0.000 0.996 0.004
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.000 0.996 0.004
E53.1 Pyridoxine deficiency
0.000 0.996 0.003
E53.0 Riboflavin deficiency
0.000 0.996 0.003
E61.1 Iron deficiency
0.000 0.996 0.003
M62.8 Other specified disorders of muscle
0.000 0.996 0.004
D46.7 Other myelodysplastic syndromes
0.003 0.996 0.000
K55.2 Angiodysplasia of colon
0.004 0.996 0.000
E63.8 Other specified nutritional deficiencies
0.000 0.997 0.003
E63.1 Imbalance of constituents of food intake
0.000 0.997 0.003
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.997 0.003
E46 Unspecified protein-energy malnutrition
0.000 0.997 0.003
E72 Other disorders of amino-acid metabolism
0.000 0.997 0.003
M62.82 Other specified disorders of muscle (Upper arm)
0.000 0.997 0.003
C43.8 Overlapping malignant melanoma of skin
0.003 0.997 0.000
C43.0 Malignant melanoma of lip
0.003 0.997 0.000
T79.7 Traumatic subcutaneous emphysema
0.000 0.997 0.003
E31 Polyglandular dysfunction
0.000 0.997 0.003
E14.8 With unspecified complications
0.000 0.997 0.003
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.997 0.003
M62.83 Other specified disorders of muscle (Forearm)
0.000 0.997 0.003
E77 Disorders of glycoprotein metabolism
0.000 0.997 0.003
E76 Disorders of glycosaminoglycan metabolism
0.000 0.997 0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.997 0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.997 0.003
E70 Disorders of aromatic amino-acid metabolism
0.000 0.997 0.003
M62.80 Other specified disorders of muscle (Multiple sites)
0.000 0.997 0.003
E75.5 Other lipid storage disorders
0.000 0.997 0.003
E88.8 Other specified metabolic disorders
0.000 0.997 0.003
E28 Ovarian dysfunction
0.000 0.997 0.003
E28.3 Primary ovarian failure
0.000 0.997 0.003
E24 Cushing's syndrome
0.000 0.997 0.003
E79 Disorders of purine and pyrimidine metabolism
0.000 0.997 0.003
E26 Hyperaldosteronism
0.000 0.997 0.003
O66.0 Obstructed labour due to shoulder dystocia
0.003 0.997 0.000
E84 Cystic fibrosis
0.000 0.997 0.003
M62.84 Other specified disorders of muscle (Hand)
0.000 0.997 0.003
E29 Testicular dysfunction
0.000 0.997 0.003
E55 Vitamin D deficiency
0.000 0.997 0.003
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.000 0.997 0.003
K83.0 Cholangitis
0.000 0.997 0.003
E21.2 Other hyperparathyroidism
0.000 0.997 0.003
Y40.9 Systemic antibiotic, unspecified
0.000 0.997 0.003
E83.3 Disorders of phosphorus metabolism
0.000 0.997 0.003
N89.5 Stricture and atresia of vagina
0.003 0.997 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.997 0.003
E63.9 Nutritional deficiency, unspecified
0.000 0.997 0.003
M62.88 Other specified disorders of muscle (Other)
0.000 0.997 0.003
D68.0 Von Willebrand's disease
0.000 0.997 0.003
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.997 0.003
E83.8 Other disorders of mineral metabolism
0.000 0.997 0.003
E83.2 Disorders of zinc metabolism
0.000 0.997 0.003
E83.0 Disorders of copper metabolism
0.000 0.997 0.003
E21.0 Primary hyperparathyroidism
0.000 0.997 0.003
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.997 0.003
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.997 0.003
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.997 0.003
E74.2 Disorders of galactose metabolism
0.000 0.997 0.003
E74.1 Disorders of fructose metabolism
0.000 0.997 0.003
E74.0 Glycogen storage disease
0.000 0.997 0.003
Z39.1 Care and examination of lactating mother
0.000 0.997 0.003
C43.1 Malignant melanoma of eyelid, including canthus
0.003 0.997 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.997 0.003
G12.9 Spinal muscular atrophy, unspecified
0.000 0.997 0.003
G12.8 Other spinal muscular atrophies and related syndromes
0.000 0.997 0.003
G12.1 Other inherited spinal muscular atrophy
0.000 0.997 0.003
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.000 0.997 0.003
M87.2 Osteonecrosis due to previous trauma
0.000 0.997 0.003
E20 Hypoparathyroidism
0.000 0.997 0.003
E89.4 Postprocedural ovarian failure
0.000 0.997 0.003
M87.9 Osteonecrosis, unspecified
0.000 0.997 0.003
E67 Other hyperalimentation
0.000 0.997 0.003
E68 Sequelae of hyperalimentation
0.000 0.997 0.003
E12.9 Without complications
0.000 0.997 0.003
E12.8 With unspecified complications
0.000 0.997 0.003
E12.7 With multiple complications
0.000 0.997 0.003
E12.6 With other specified complications
0.000 0.997 0.003
E12.5 With peripheral circulatory complications
0.000 0.997 0.003
E12.4 With neurological complications
0.000 0.997 0.003
E12.3 With ophthalmic complications
0.000 0.997 0.003
E12.2 With renal complications
0.000 0.997 0.003
E12.1 With ketoacidosis
0.000 0.997 0.003
E12.0 With coma
0.000 0.997 0.003
E75.6 Lipid storage disorder, unspecified
0.000 0.997 0.003
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.997 0.003
E75.3 Sphingolipidosis, unspecified
0.000 0.997 0.003
E75.1 Other gangliosidosis
0.000 0.997 0.003
E75.0 GM2 gangliosidosis
0.000 0.997 0.003
E73 Lactose intolerance
0.000 0.997 0.003
E13.8 With unspecified complications
0.000 0.997 0.003
E13.7 With multiple complications
0.000 0.997 0.003
E13.6 With other specified complications
0.000 0.997 0.003
E13.5 With peripheral circulatory complications
0.000 0.997 0.003
E13.4 With neurological complications
0.000 0.997 0.003
E13.2 With renal complications
0.000 0.997 0.003
E13.1 With ketoacidosis
0.000 0.997 0.003
E13.0 With coma
0.000 0.997 0.003
E88.9 Metabolic disorder, unspecified
0.000 0.997 0.003
E25.9 Adrenogenital disorder, unspecified
0.000 0.997 0.003
E25.8 Other adrenogenital disorders
0.000 0.997 0.003
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.997 0.003
E72.0 Disorders of amino-acid transport
0.000 0.997 0.003
K70.2 Alcoholic fibrosis and sclerosis of liver
0.003 0.997 0.000
E13.9 Without complications
0.000 0.997 0.003
F42.9 Obsessive-compulsive disorder, unspecified
0.003 0.997 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.997 0.003
E85 Amyloidosis
0.000 0.997 0.003
E13.3 With ophthalmic complications
0.000 0.997 0.003
E30.9 Disorder of puberty, unspecified
0.000 0.997 0.003
E30.8 Other disorders of puberty
0.000 0.997 0.003
E30.1 Precocious puberty
0.000 0.997 0.003
E30.0 Delayed puberty
0.000 0.997 0.003
E32.9 Disease of thymus, unspecified
0.000 0.997 0.003
E32.8 Other diseases of thymus
0.000 0.997 0.003
E32.1 Abscess of thymus
0.000 0.997 0.003
E32.0 Persistent hyperplasia of thymus
0.000 0.997 0.003
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.997 0.003
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.997 0.003
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.997 0.003
E75.2 Other sphingolipidosis
0.000 0.997 0.003
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.997 0.003
E21.3 Hyperparathyroidism, unspecified
0.000 0.997 0.003
E53.9 Vitamin B deficiency, unspecified
0.000 0.997 0.003
O47.1 False labour at or after 37 completed weeks of gestation
0.003 0.997 0.000
O47.0 False labour before 37 completed weeks of gestation
0.003 0.997 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.000 0.997 0.003
E23.6 Other disorders of pituitary gland
0.000 0.997 0.002
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.997 0.003
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.997 0.003
E72.5 Disorders of glycine metabolism
0.000 0.997 0.003
E72.4 Disorders of ornithine metabolism
0.000 0.997 0.003
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.997 0.003
E72.2 Disorders of urea cycle metabolism
0.000 0.997 0.003
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.997 0.003
E31.9 Polyglandular dysfunction, unspecified
0.000 0.997 0.003
E31.8 Other polyglandular dysfunction
0.000 0.997 0.003
E31.1 Polyglandular hyperfunction
0.000 0.997 0.003
K70.0 Alcoholic fatty liver
0.003 0.997 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.997 0.003
D68.6 Other Thrombophilia
0.000 0.997 0.003
E71.3 Disorders of fatty-acid metabolism
0.000 0.997 0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.997 0.002
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.997 0.002
E71.0 Maple-syrup-urine disease
0.000 0.997 0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.997 0.002
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.997 0.002
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.997 0.002
E76.2 Other mucopolysaccharidoses
0.000 0.997 0.002
E76.1 Mucopolysaccharidosis, type II
0.000 0.997 0.002
E76.0 Mucopolysaccharidosis, type I
0.000 0.997 0.002
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.997 0.002
E77.8 Other disorders of glycoprotein metabolism
0.000 0.997 0.002
E77.1 Defects in glycoprotein degradation
0.000 0.997 0.002
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.997 0.002
E24.0 Pituitary-dependent Cushing's disease
0.000 0.997 0.003
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.997 0.002
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.997 0.002
E70.2 Disorders of tyrosine metabolism
0.000 0.997 0.002
E70.1 Other hyperphenylalaninaemias
0.000 0.997 0.002
E70.0 Classical phenylketonuria
0.000 0.997 0.002
E28.9 Ovarian dysfunction, unspecified
0.000 0.997 0.002
E28.8 Other ovarian dysfunction
0.000 0.997 0.002
E28.1 Androgen excess
0.000 0.997 0.002
E28.0 Oestrogen excess
0.000 0.997 0.002
E70.3 Albinism
0.000 0.997 0.002
K70.4 Alcoholic hepatic failure
0.003 0.997 0.000
E24.8 Other Cushing's syndrome
0.000 0.997 0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.997 0.002
E24.3 Ectopic ACTH syndrome
0.000 0.997 0.002
E24.1 Nelson's syndrome
0.000 0.997 0.002
E26.9 Hyperaldosteronism, unspecified
0.000 0.997 0.002
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.997 0.002
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.997 0.002
E79.1 Lesch-Nyhan syndrome
0.000 0.997 0.002
M96.0 Pseudarthrosis after fusion or arthrodesis
0.003 0.997 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.997 0.002
T79-T79 Certain early complications of trauma
0.000 0.997 0.003
E26.8 Other hyperaldosteronism
0.000 0.997 0.002
E26.1 Secondary hyperaldosteronism
0.000 0.997 0.002
S62.3 Fracture of other metacarpal bone
0.000 0.997 0.003
S20 Superficial injury of thorax
0.003 0.997 0.000
D68.8 Other specified coagulation defects
0.000 0.997 0.003
D68.2 Hereditary deficiency of other clotting factors
0.000 0.997 0.003
E84.8 Cystic fibrosis with other manifestations
0.000 0.997 0.002
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.997 0.002
M62.81 Other specified disorders of muscle (Shoulder region)
0.000 0.997 0.002
E29.9 Testicular dysfunction, unspecified
0.000 0.997 0.002
E29.8 Other testicular dysfunction
0.000 0.997 0.002
E29.0 Testicular hyperfunction
0.000 0.997 0.002
E55.0 Rickets, active
0.000 0.997 0.002
D68 Other coagulation defects
0.000 0.997 0.003
M87 Osteonecrosis
0.000 0.997 0.002
C43.2 Malignant melanoma of ear and external auricular canal
0.002 0.997 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.997 0.002
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.997 0.002
S20.0 Contusion of breast
0.002 0.997 0.000
E83.4 Disorders of magnesium metabolism
0.000 0.997 0.003
Y40.1 Cefalosporins and other -lactam antibiotics
0.000 0.997 0.002
F81.9 Developmental disorder of scholastic skills, unspecified
0.002 0.998 0.000
E88.3 Tumour lysis syndrome
0.000 0.998 0.002
K50.8 Other Crohn's disease
0.000 0.998 0.002
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)
0.000 0.998 0.002
E24.9 Cushing's syndrome, unspecified
0.000 0.998 0.002
E24.2 Drug-induced Cushing's syndrome
0.000 0.998 0.002
E84.9 Cystic fibrosis, unspecified
0.000 0.998 0.002
M87.29 Osteonecrosis due to previous trauma (Site unspecified)
0.000 0.998 0.002
M87.28 Osteonecrosis due to previous trauma (Other)
0.000 0.998 0.002
M87.26 Osteonecrosis due to previous trauma (Lower leg)
0.000 0.998 0.002
M87.24 Osteonecrosis due to previous trauma (Hand)
0.000 0.998 0.002
M87.23 Osteonecrosis due to previous trauma (Forearm)
0.000 0.998 0.002
M87.22 Osteonecrosis due to previous trauma (Upper arm)
0.000 0.998 0.002
M87.21 Osteonecrosis due to previous trauma (Shoulder region)
0.000 0.998 0.002
E20.8 Other hypoparathyroidism
0.000 0.998 0.002
E20.1 Pseudohypoparathyroidism
0.000 0.998 0.002
E20.0 Idiopathic hypoparathyroidism
0.000 0.998 0.002
M62.89 Other specified disorders of muscle (Site unspecified)
0.000 0.998 0.002
M87.99 Osteonecrosis, unspecified (Site unspecified)
0.000 0.998 0.002
M87.94 Osteonecrosis, unspecified (Hand)
0.000 0.998 0.002
M87.93 Osteonecrosis, unspecified (Forearm)
0.000 0.998 0.002
M87.92 Osteonecrosis, unspecified (Upper arm)
0.000 0.998 0.002
M87.90 Osteonecrosis, unspecified (Multiple sites)
0.000 0.998 0.002
E67.8 Other specified hyperalimentation
0.000 0.998 0.002
E67.3 Hypervitaminosis D
0.000 0.998 0.002
E67.2 Megavitamin-B6 syndrome
0.000 0.998 0.002
E67.1 Hypercarotenaemia
0.000 0.998 0.002
E67.0 Hypervitaminosis A
0.000 0.998 0.002
E73.8 Other lactose intolerance
0.000 0.998 0.002
E73.1 Secondary lactase deficiency
0.000 0.998 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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