TreeWAS – Variant ID: rs2237349

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M20.1 Hallux valgus (acquired)	0.841	0.159	0.000
M20.4 Other hammer toe(s) (acquired)	0.830	0.170	0.000
M20 Acquired deformities of fingers and toes	0.827	0.173	0.000
M20.3 Other deformity of hallux (acquired)	0.720	0.280	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.659	0.341	0.000
M20.5 Other deformities of toe(s) (acquired)	0.470	0.530	0.000
M20.0 Deformity of finger(s)	0.401	0.599	0.000
M20.2 Hallux rigidus	0.359	0.641	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.148	0.852	0.000
C79 Secondary malignant neoplasm of other sites	0.140	0.860	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.137	0.863	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.131	0.869	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.124	0.876	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.114	0.886	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.095	0.905	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.089	0.911	0.000
C79.6 Secondary malignant neoplasm of ovary	0.079	0.921	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.075	0.925	0.000
E55.9 Vitamin D deficiency, unspecified	0.047	0.953	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.042	0.958	0.000
C79.2 Secondary malignant neoplasm of skin	0.042	0.958	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.040	0.960	0.000
C76.0 Head, face and neck	0.036	0.964	0.000
C76.1 Thorax	0.033	0.967	0.000
C80 Malignant neoplasm without specification of site	0.033	0.967	0.000
C76.2 Abdomen	0.031	0.969	0.000
C76.3 Pelvis	0.029	0.970	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.029	0.971	0.000
C76.7 Other ill-defined sites	0.029	0.971	0.000
C76.5 Lower limb	0.029	0.971	0.000
C76.4 Upper limb	0.029	0.971	0.000
C80.9 Malignant neoplasm, unspecified	0.028	0.972	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.028	0.972	0.000
I60 Subarachnoid haemorrhage	0.025	0.975	0.000
E55 Vitamin D deficiency	0.024	0.976	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.023	0.976	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.023	0.977	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.022	0.978	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.022	0.978	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.020	0.980	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.020	0.980	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.018	0.982	0.000
E55.0 Rickets, active	0.017	0.983	0.000
I60.8 Other subarachnoid haemorrhage	0.016	0.984	0.000
D63.0 Anaemia in neoplastic disease	0.016	0.984	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.015	0.984	0.000
C34.3 Lower lobe, bronchus or lung	0.016	0.984	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.014	0.986	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.013	0.987	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.012	0.988	0.000
C78.0 Secondary malignant neoplasm of lung	0.012	0.988	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.012	0.988	0.000
C34.9 Bronchus or lung, unspecified	0.011	0.989	0.000
C34 Malignant neoplasm of bronchus and lung	0.011	0.989	0.000
Y43.3 Other antineoplastic drugs	0.011	0.989	0.000
C78.7 Secondary malignant neoplasm of liver	0.009	0.991	0.000
C34.2 Middle lobe, bronchus or lung	0.009	0.991	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.009	0.991	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.008	0.992	0.000
C78.2 Secondary malignant neoplasm of pleura	0.008	0.992	0.000
N20.2 Calculus of kidney with calculus of ureter	0.008	0.992	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.008	0.992	0.000
Z93.2 Ileostomy status	0.000	0.992	0.008
C78.4 Secondary malignant neoplasm of small intestine	0.008	0.992	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.992	0.008
E50-E64 Other nutritional deficiencies	0.008	0.992	0.000
C34.1 Upper lobe, bronchus or lung	0.008	0.992	0.000
C34.8 Overlapping lesion of bronchus and lung	0.007	0.992	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.007	0.993	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.007	0.993	0.000
E58 Dietary calcium deficiency	0.007	0.993	0.000
E63 Other nutritional deficiencies	0.006	0.994	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.006	0.994	0.000
Y85.0 Sequelae of motor-vehicle accident	0.006	0.994	0.000
Y43 Primarily systemic agents	0.006	0.994	0.000
Y83.3 Surgical operation with formation of external stoma	0.000	0.994	0.006
E64 Sequelae of malnutrition and other nutritional deficiencies	0.006	0.994	0.000
E50 Vitamin A deficiency	0.006	0.994	0.000
E60 Dietary zinc deficiency	0.006	0.994	0.000
E59 Dietary selenium deficiency	0.006	0.994	0.000
E52 Niacin deficiency [pellagra]	0.006	0.994	0.000
E54 Ascorbic acid deficiency	0.006	0.994	0.000
E51 Thiamine deficiency	0.005	0.994	0.000
E56 Other vitamin deficiencies	0.005	0.994	0.000
F01.9 Vascular dementia, unspecified	0.005	0.995	0.000
C34.0 Main bronchus	0.005	0.995	0.000
Y43.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.995	0.005
E63.9 Nutritional deficiency, unspecified	0.005	0.995	0.000
Y43.2 Antineoplastic natural products	0.005	0.995	0.000
E63.8 Other specified nutritional deficiencies	0.004	0.995	0.000
E63.1 Imbalance of constituents of food intake	0.004	0.995	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.004	0.995	0.000
E61 Deficiency of other nutrient elements	0.004	0.995	0.000
H02.5 Other disorders affecting eyelid function	0.004	0.996	0.000
H44.2 Degenerative myopia	0.004	0.996	0.000
Y43.9 Primarily systemic agent, unspecified	0.004	0.996	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.004	0.996	0.000
Y43.6 Enzymes, not elsewhere classified	0.004	0.996	0.000
Y43.5 Acidifying and alkalising agents	0.004	0.996	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.004	0.996	0.000
E50.9 Vitamin A deficiency, unspecified	0.004	0.996	0.000
E50.8 Other manifestations of vitamin A deficiency	0.004	0.996	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.004	0.996	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.004	0.996	0.000
E50.5 Vitamin A deficiency with night blindness	0.004	0.996	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.004	0.996	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.004	0.996	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.004	0.996	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.004	0.996	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.004	0.996	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.004	0.996	0.000
E64.8 Sequelae of other nutritional deficiencies	0.004	0.996	0.000
E64.3 Sequelae of rickets	0.004	0.996	0.000
E64.2 Sequelae of vitamin C deficiency	0.004	0.996	0.000
E64.1 Sequelae of vitamin A deficiency	0.004	0.996	0.000
E64.0 Sequelae of protein-energy malnutrition	0.004	0.996	0.000
Y43.1 Antineoplastic antimetabolites	0.004	0.996	0.000
E51.9 Thiamine deficiency, unspecified	0.004	0.996	0.000
E51.8 Other manifestations of thiamine deficiency	0.004	0.996	0.000
E51.1 Beriberi	0.004	0.996	0.000
Y85 Sequelae of transport accidents	0.004	0.996	0.000
E56.9 Vitamin deficiency, unspecified	0.004	0.996	0.000
E56.8 Deficiency of other vitamins	0.004	0.996	0.000
E56.0 Deficiency of vitamin E	0.004	0.996	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.004	0.996	0.000
E51.2 Wernicke's encephalopathy	0.004	0.996	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.996	0.004
E56.1 Deficiency of vitamin K	0.004	0.996	0.000
Y43.4 Immunosuppressive agents	0.004	0.996	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.996	0.004
E53 Deficiency of other B group vitamins	0.004	0.996	0.000
Z93.3 Colostomy status	0.000	0.996	0.004
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.996	0.004
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.996	0.004
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
M41.9 Scoliosis, unspecified	0.004	0.996	0.000
E61.9 Deficiency of nutrient element, unspecified	0.003	0.996	0.000
E61.8 Deficiency of other specified nutrient elements	0.003	0.996	0.000
E61.7 Deficiency of multiple nutrient elements	0.003	0.996	0.000
E61.6 Vanadium deficiency	0.003	0.996	0.000
E61.5 Molybdenum deficiency	0.003	0.996	0.000
E61.4 Chromium deficiency	0.003	0.996	0.000
E61.3 Manganese deficiency	0.003	0.996	0.000
E61.0 Copper deficiency	0.003	0.996	0.000
E61.2 Magnesium deficiency	0.003	0.997	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.003	0.997	0.000
N81.6 Rectocele	0.003	0.997	0.000
H02.1 Ectropion of eyelid	0.003	0.997	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.997	0.003
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.997	0.003
Z36.8 Other antenatal screening	0.000	0.997	0.003
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.997	0.003
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.003	0.997	0.000
E53.1 Pyridoxine deficiency	0.003	0.997	0.000
E53.0 Riboflavin deficiency	0.003	0.997	0.000
I84.5 External haemorrhoids without complication	0.000	0.997	0.003
M41.94 Scoliosis, unspecified (Thoracic region)	0.003	0.997	0.000
O28 Abnormal findings on antenatal screening of mother	0.000	0.997	0.003
G62 Other polyneuropathies	0.000	0.997	0.003
Y54.3 Benzothiadiazine derivatives	0.003	0.997	0.000
E53.9 Vitamin B deficiency, unspecified	0.003	0.997	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.997	0.003
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
C32.1 Supraglottis	0.003	0.997	0.000
C32 Malignant neoplasm of larynx	0.003	0.997	0.000
S42.10 Fracture of scapula (closed)	0.000	0.997	0.003
O80.8 Other single spontaneous delivery	0.000	0.997	0.003
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
C71.9 Brain, unspecified	0.000	0.997	0.003
J47 Bronchiectasis	0.000	0.997	0.003
D27 Benign neoplasm of ovary	0.000	0.997	0.003
C31 Malignant neoplasm of accessory sinuses	0.002	0.997	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.003	0.997	0.000
G12.2 Motor neuron disease	0.000	0.997	0.003
G62.8 Other specified polyneuropathies	0.000	0.997	0.003
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.997	0.002
M41.92 Scoliosis, unspecified (Cervical region)	0.002	0.997	0.000
N83.1 Corpus luteum cyst	0.000	0.997	0.003
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.003	0.997	0.000
C32.3 Laryngeal cartilage	0.002	0.997	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.002	0.997	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.998	0.002
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.998	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.998	0.002
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.998	0.002
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.998	0.002
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.998	0.002
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.998	0.002
G62.2 Polyneuropathy due to other toxic agents	0.000	0.998	0.002
G62.1 Alcoholic polyneuropathy	0.000	0.998	0.002
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.002	0.998	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.998	0.002
C77.3 Axillary and upper limb lymph nodes	0.002	0.998	0.000
M23.49 Loose body in knee-Unspec lig/men	0.000	0.998	0.002
G62.0 Drug-induced polyneuropathy	0.000	0.998	0.002
C32.8 Overlapping lesion of larynx	0.002	0.998	0.000
C32.2 Subglottis	0.002	0.998	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.998	0.002
C31.0 Maxillary sinus	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.000	0.998	0.002
C77.0 Lymph nodes of head, face and neck	0.002	0.998	0.000
G60.0 Hereditary motor and sensory neuropathy	0.000	0.998	0.002
I70.00 Atherosclerosis of aorta (without gangrene)	0.002	0.998	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
C33 Malignant neoplasm of trachea	0.002	0.998	0.000
E61.1 Iron deficiency	0.002	0.998	0.000
M41 Scoliosis	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
C31.9 Accessory sinus, unspecified	0.002	0.998	0.000
C31.8 Overlapping lesion of accessory sinuses	0.002	0.998	0.000
C31.3 Sphenoidal sinus	0.002	0.998	0.000
C31.2 Frontal sinus	0.002	0.998	0.000
C31.1 Ethmoidal sinus	0.002	0.998	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
C38 Malignant neoplasm of heart, mediastinum and pleura	0.002	0.998	0.000
C37 Malignant neoplasm of thymus	0.002	0.998	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
M79.58 Residual foreign body in soft tissue (Other)	0.002	0.998	0.000
C39.9 Ill-defined sites within the respiratory system	0.002	0.998	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.002	0.998	0.000
C39.0 Upper respiratory tract, part unspecified	0.002	0.998	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.002	0.998	0.000
O81.4 Vacuum extractor delivery	0.000	0.998	0.002
S49 Other and unspecified injuries of shoulder and upper arm	0.000	0.998	0.002
M41.5 Other secondary scoliosis	0.002	0.998	0.000
O80 Single spontaneous delivery	0.000	0.998	0.002
C71.3 Parietal lobe	0.000	0.998	0.002
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
G60 Hereditary and idiopathic neuropathy	0.000	0.998	0.002
C32.0 Glottis	0.002	0.998	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.998	0.002
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
G37 Other demyelinating diseases of central nervous system	0.002	0.998	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.002	0.998	0.000
C32.9 Larynx, unspecified	0.002	0.998	0.000
K90.0 Coeliac disease	0.000	0.998	0.002
S42.1 Fracture of scapula	0.000	0.998	0.002
Z01.5 Diagnostic skin and sensitisation tests	0.002	0.998	0.000
O80.9 Single spontaneous delivery, unspecified	0.000	0.998	0.002
M25.57 Pain in joint (Ankle and foot)	0.002	0.998	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.002	0.998	0.000
C77.1 Intrathoracic lymph nodes	0.002	0.998	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.000	0.998	0.002
J38.7 Other diseases of larynx	0.000	0.998	0.002
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
Z29.0 Isolation	0.000	0.998	0.002
C30.1 Middle ear	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.002	0.998	0.000
M41.8 Other forms of scoliosis	0.002	0.998	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
M41.4 Neuromuscular scoliosis	0.002	0.998	0.000
M41.3 Thoracogenic scoliosis	0.002	0.998	0.000
M41.2 Other idiopathic scoliosis	0.002	0.998	0.000
M41.1 Juvenile idiopathic scoliosis	0.002	0.998	0.000
M41.0 Infantile idiopathic scoliosis	0.002	0.998	0.000
N80.1 Endometriosis of ovary	0.000	0.998	0.002
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.998	0.002
F01 Vascular dementia	0.002	0.998	0.000
K36 Other appendicitis	0.000	0.998	0.002
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.002	0.998	0.000
C38.2 Posterior mediastinum	0.002	0.998	0.000
C38.1 Anterior mediastinum	0.002	0.998	0.000
C38.0 Heart	0.002	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
S42.0 Fracture of clavicle	0.000	0.998	0.002
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
T59.8 Other specified gases, fumes and vapours	0.002	0.998	0.000
I63 Cerebral infarction	0.000	0.998	0.002
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.998	0.002
C38.3 Mediastinum, part unspecified	0.001	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
S62.2 Fracture of first metacarpal bone	0.000	0.998	0.002
M79.5 Residual foreign body in soft tissue	0.002	0.998	0.000
O61.0 Failed medical induction of labour	0.002	0.998	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.000	0.998	0.002
M41.59 Other secondary scoliosis (Site unspecified)	0.002	0.998	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.002	0.998	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.002	0.998	0.000
M41.54 Other secondary scoliosis (Thoracic region)	0.002	0.998	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.002	0.998	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.002	0.998	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.002	0.998	0.000
O80.1 Spontaneous breech delivery	0.000	0.998	0.002
M54.36 Sciatica (Lumbar region)	0.000	0.998	0.002
G60.3 Idiopathic progressive neuropathy	0.000	0.998	0.002
G60.2 Neuropathy in association with hereditary ataxia	0.000	0.998	0.002
G60.1 Refsum's disease	0.000	0.998	0.002
N81.8 Other female genital prolapse	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.002	0.998	0.000
G37.5 Concentric sclerosis [Balo]	0.002	0.998	0.000
G37.4 Subacute necrotising myelitis	0.002	0.998	0.000
G37.2 Central pontine myelinolysis	0.002	0.998	0.000
G37.1 Central demyelination of corpus callosum	0.002	0.998	0.000
G37.0 Diffuse sclerosis	0.002	0.998	0.000
L05.0 Pilonidal cyst with abscess	0.000	0.998	0.002
S42.11 Fracture of scapula (open)	0.000	0.998	0.002
C30.0 Nasal cavity	0.001	0.998	0.000
S20.2 Contusion of thorax	0.000	0.998	0.002
M41.89 Other forms of scoliosis (Site unspecified)	0.001	0.998	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.001	0.998	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.001	0.998	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.001	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
C77.9 Lymph node, unspecified	0.002	0.998	0.000
Q24.0 Dextrocardia	0.002	0.998	0.000
S20.3 Other superficial injuries of front wall of thorax	0.000	0.998	0.002
Z52.4 Kidney donor	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.000	0.998	0.002
C71.8 Overlapping lesion of brain	0.000	0.998	0.002
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.002	0.998	0.000
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.001	0.998	0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)	0.001	0.998	0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)	0.001	0.998	0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)	0.001	0.998	0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)	0.001	0.998	0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)	0.001	0.998	0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.29 Other idiopathic scoliosis (Site unspecified)	0.001	0.998	0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.26 Other idiopathic scoliosis (Lumbar region)	0.001	0.998	0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.24 Other idiopathic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.22 Other idiopathic scoliosis (Cervical region)	0.001	0.998	0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.39 Thoracogenic scoliosis-Site unspe	0.001	0.998	0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ	0.001	0.998	0.000
M41.37 Thoracogenic scoliosis-Lumbosacral	0.001	0.998	0.000
M41.36 Thoracogenic scoliosis-Lumbar	0.001	0.998	0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.34 Thoracogenic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.32 Thoracogenic scoliosis-Cervical	0.001	0.998	0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl	0.001	0.998	0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.49 Neuromuscular scoliosis (Site unspecified)	0.001	0.998	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.46 Neuromuscular scoliosis (Lumbar region)	0.001	0.998	0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.44 Neuromuscular scoliosis (Thoracic region)	0.001	0.998	0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.42 Neuromuscular scoliosis (Cervical region)	0.001	0.998	0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
F01.8 Other vascular dementia	0.001	0.998	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.001	0.998	0.000
F01.2 Subcortical vascular dementia	0.001	0.998	0.000
F01.0 Vascular dementia of acute onset	0.001	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M79.56 Residual foreign body in soft tissue (Lower leg)	0.001	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
S22.20 Fracture of sternum (closed)	0.002	0.998	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.000	0.998	0.001
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
O82 Single delivery by Caesarean section	0.000	0.998	0.002
O81 Single delivery by forceps and vacuum extractor	0.000	0.998	0.002
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.998	0.001
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.998	0.001
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.001
G12 Spinal muscular atrophy and related syndromes	0.000	0.998	0.002
M94.26 Chondromalacia (Lower leg)	0.000	0.998	0.001
S62.21 Fracture of first metacarpal bone (open)	0.000	0.998	0.001
G37.8 Other specified demyelinating diseases of central nervous system	0.001	0.998	0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.001	0.998	0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.001	0.998	0.000
M79.52 Residual foreign body in soft tissue (Upper arm)	0.001	0.998	0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.001	0.998	0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.001	0.998	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.000	0.998	0.002
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
Z36 Antenatal screening	0.000	0.998	0.002
Z93 Artificial opening status	0.000	0.998	0.002
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.998	0.001
K05.3 Chronic periodontitis	0.000	0.998	0.002
Y52.3 Coronary vasodilators, not elsewhere classified	0.001	0.998	0.000
G61 Inflammatory polyneuropathy	0.000	0.998	0.001
S42.01 Fracture of clavicle (open)	0.000	0.998	0.001
C38.4 Pleura	0.001	0.998	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.998	0.001
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.999	0.001
M79.53 Residual foreign body in soft tissue (Forearm)	0.001	0.999	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.000	0.999	0.001
O82.0 Delivery by elective Caesarean section	0.000	0.999	0.001
C44.5 Skin of trunk	0.000	0.999	0.001
O80-O84 Delivery	0.000	0.999	0.001
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.999	0.001
C71.4 Occipital lobe	0.000	0.999	0.001
G61.0 Guillain-Barre syndrome	0.000	0.999	0.001
O82.9 Delivery by Caesarean section, unspecified	0.000	0.999	0.001
O82.1 Delivery by emergency Caesarean section	0.000	0.999	0.001
Y52.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
G64 Other disorders of peripheral nervous system	0.000	0.999	0.001
D40.0 Prostate	0.000	0.999	0.001
L71.1 Rhinophyma	0.001	0.999	0.000
O22.4 Haemorrhoids in pregnancy	0.000	0.999	0.001
Q24.4 Congenital subaortic stenosis	0.001	0.999	0.000
M23.43 Loose body in knee-Med lig/oth men	0.000	0.999	0.001
F62.9 Enduring personality change, unspecified	0.001	0.999	0.000
M23.0 Cystic meniscus	0.000	0.999	0.001
N90.4 Leukoplakia of vulva	0.001	0.999	0.000
Q24.3 Pulmonary infundibular stenosis	0.001	0.999	0.000
Q24.2 Cor triatriatum	0.001	0.999	0.000
Q24.1 Levocardia	0.001	0.999	0.000
Z85.9 Personal history of malignant neoplasm, unspecified	0.001	0.999	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.999	0.001
C71.1 Frontal lobe	0.000	0.999	0.001
C71.0 Cerebrum, except lobes and ventricles	0.000	0.999	0.001
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.999	0.001
O81.2 Mid-cavity forceps with rotation	0.000	0.999	0.001
O81.1 Mid-cavity forceps delivery	0.000	0.999	0.001
O82.8 Other single delivery by Caesarean section	0.000	0.999	0.001
O82.2 Delivery by Caesarean hysterectomy	0.000	0.999	0.001
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.999	0.001
Y52.7 Peripheral vasodilators	0.001	0.999	0.000
Y89.9 Sequelae of unspecified external cause	0.001	0.999	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.999	0.001
Z49.0 Preparatory care for dialysis	0.001	0.999	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
C71.6 Cerebellum	0.000	0.999	0.001
G12.9 Spinal muscular atrophy, unspecified	0.000	0.999	0.001
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.999	0.001
G12.1 Other inherited spinal muscular atrophy	0.000	0.999	0.001
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.999	0.001
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.999	0.001
I70.0 Atherosclerosis of aorta	0.001	0.999	0.000
O22 Venous complications in pregnancy	0.000	0.999	0.001
K08.3 Retained dental root	0.000	0.999	0.001
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.999	0.001
M23.4 Loose body in knee	0.000	0.999	0.001
T17.3 Foreign body in larynx	0.001	0.999	0.000
Z36.5 Antenatal screening for isoimmunisation	0.000	0.999	0.001
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.000	0.999	0.001
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.999	0.001
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.999	0.001
C71.7 Brain stem	0.000	0.999	0.001
F01.1 Multi-infarct dementia	0.001	0.999	0.000
G61.1 Serum neuropathy	0.000	0.999	0.001
H66.9 Otitis media, unspecified	0.000	0.999	0.001
M67.2 Synovial hypertrophy, not elsewhere classified	0.001	0.999	0.000
O22.1 Genital varices in pregnancy	0.000	0.999	0.001
S20.1 Other and unspecified superficial injuries of breast	0.000	0.999	0.001
T17.8 Foreign body in other and multiple parts of respiratory tract	0.001	0.999	0.000
T17.2 Foreign body in pharynx	0.001	0.999	0.000
H44.8 Other disorders of globe	0.001	0.999	0.000
I85.0 Oesophageal varices with bleeding	0.000	0.999	0.001
K05.0 Acute gingivitis	0.000	0.999	0.001
T17.5 Foreign body in bronchus	0.001	0.999	0.000
H44 Disorders of globe	0.001	0.999	0.000
S82.50 Fracture of medial malleolus (closed)	0.001	0.999	0.000
O21.8 Other vomiting complicating pregnancy	0.000	0.999	0.001
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.999	0.001
C71.5 Cerebral ventricle	0.000	0.999	0.001
O81.0 Low forceps delivery	0.000	0.999	0.001
Q24.6 Congenital heart block	0.001	0.999	0.000
M23.07 Cystic meniscus-Capsular lig	0.000	0.999	0.001
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.000	0.999	0.001
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.999	0.001
M23.00 Cystic meniscus (Multiple sites)	0.000	0.999	0.001
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.999	0.001
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.999	0.001
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.999	0.001
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.999	0.001
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.999	0.001
G63.1 Polyneuropathy in neoplastic disease	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations