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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2239524
log Bayes Factor = 79.6129
Chromosome 6   position 31,125,569  (GRCh37) Explore rs2239524 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.003 0.997
E10 Insulin-dependent diabetes mellitus
0.000 0.021 0.979
E10.9 Without complications
0.000 0.030 0.970
L40.0 Psoriasis vulgaris
0.000 0.043 0.957
E05.9 Thyrotoxicosis, unspecified
0.000 0.054 0.946
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.056 0.944
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.057 0.943
E11.0 With coma
0.000 0.058 0.942
E00-E07 Disorders of thyroid gland
0.000 0.065 0.935
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.075 0.925
E70-E90 Metabolic disorders
0.000 0.083 0.917
E78.5 Hyperlipidaemia, unspecified
0.000 0.087 0.913
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.093 0.907
E78.0 Pure hypercholesterolaemia
0.000 0.109 0.891
E14 Unspecified diabetes mellitus
0.000 0.113 0.887
E11.4 With neurological complications
0.000 0.131 0.869
E10.3 With ophthalmic complications
0.000 0.131 0.869
L40.8 Other psoriasis
0.000 0.161 0.839
L40.1 Generalised pustular psoriasis
0.000 0.169 0.831
E10.2 With renal complications
0.000 0.181 0.819
E13 Other specified diabetes mellitus
0.000 0.184 0.816
K90 Intestinal malabsorption
0.000 0.188 0.812
E78.4 Other hyperlipidaemia
0.000 0.199 0.801
E78.2 Mixed hyperlipidaemia
0.000 0.203 0.797
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.207 0.793
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.209 0.791
E78.8 Other disorders of lipoprotein metabolism
0.000 0.209 0.791
E14.3 With ophthalmic complications
0.000 0.222 0.778
E79 Disorders of purine and pyrimidine metabolism
0.000 0.225 0.775
E11.2 With renal complications
0.000 0.227 0.773
L40.4 Guttate psoriasis
0.000 0.237 0.763
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.238 0.762
E10.8 With unspecified complications
0.000 0.244 0.756
E14.8 With unspecified complications
0.000 0.280 0.720
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E14.2 Withrenal complications
0.000 0.295 0.705
E13.9 Without complications
0.000 0.298 0.702
E10.7 With multiple complications
0.000 0.298 0.702
E11.5 With peripheral circulatory complications
0.000 0.299 0.701
E14.5 With peripheral circulatory complications
0.000 0.305 0.695
E88 Other metabolic disorders
0.000 0.316 0.684
E74 Other disorders of carbohydrate metabolism
0.000 0.317 0.683
E16 Other disorders of pancreatic internal secretion
0.000 0.319 0.681
E80.4 Gilbert's syndrome
0.000 0.324 0.676
E05.5 Thyroid crisis or storm
0.000 0.324 0.676
E05.4 Thyrotoxicosis factitia
0.000 0.324 0.676
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.324 0.676
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.324 0.676
E11.7 With multiple complications
0.000 0.325 0.675
E10.1 With ketoacidosis
0.000 0.326 0.674
E70 Disorders of aromatic amino-acid metabolism
0.000 0.326 0.673
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.328 0.672
E85 Amyloidosis
0.000 0.328 0.672
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.330 0.670
E00 Congenital iodine-deficiency syndrome
0.000 0.330 0.670
E78.3 Hyperchylomicronaemia
0.000 0.337 0.663
E77 Disorders of glycoprotein metabolism
0.000 0.342 0.658
E76 Disorders of glycosaminoglycan metabolism
0.000 0.342 0.658
E72 Other disorders of amino-acid metabolism
0.000 0.342 0.658
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.342 0.658
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.342 0.658
E11.1 With ketoacidosis
0.000 0.348 0.652
E78.6 Lipoprotein deficiency
0.000 0.352 0.648
K90.8 Other intestinal malabsorption
0.000 0.359 0.641
E14.7 With multiple complications
0.000 0.364 0.636
E11.8 With unspecified complications
0.000 0.367 0.633
E78.1 Pure hyperglyceridaemia
0.000 0.367 0.633
E14.4 With neurological complications
0.000 0.371 0.628
E14.0 With coma
0.000 0.373 0.627
E80.6 Other disorders of bilirubin metabolism
0.000 0.375 0.625
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.375 0.625
E14.6 With other specified complications
0.000 0.383 0.617
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.389 0.610
L40.3 Pustulosis palmaris et plantaris
0.000 0.396 0.604
E06 Thyroiditis
0.000 0.396 0.604
E16.2 Hypoglycaemia, unspecified
0.000 0.401 0.599
E13.8 With unspecified complications
0.000 0.415 0.585
E13.7 With multiple complications
0.000 0.415 0.585
E13.6 With other specified complications
0.000 0.415 0.585
E13.5 With peripheral circulatory complications
0.000 0.415 0.585
E13.4 With neurological complications
0.000 0.415 0.585
E13.2 With renal complications
0.000 0.415 0.585
E13.1 With ketoacidosis
0.000 0.415 0.585
E13.0 With coma
0.000 0.415 0.585
K90.3 Pancreatic steatorrhoea
0.000 0.417 0.582
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.417 0.582
K90.1 Tropical sprue
0.000 0.417 0.582
E84 Cystic fibrosis
0.000 0.423 0.576
E80.1 Porphyria cutanea tarda
0.000 0.425 0.575
E10.0 With coma
0.000 0.425 0.575
E05.8 Other thyrotoxicosis
0.000 0.429 0.571
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.431 0.568
E80.5 Crigler-Najjar syndrome
0.000 0.431 0.568
E80.3 Defects of catalase and peroxydase
0.000 0.431 0.568
E80.0 Hereditary erythropoietic porphyria
0.000 0.431 0.568
E88.8 Other specified metabolic disorders
0.000 0.432 0.568
E15 Nondiabetic hypoglycaemic coma
0.000 0.433 0.567
E14.9 Without complications
0.000 0.433 0.567
L40-L45 Papulosquamous disorders
0.000 0.434 0.566
E10.6 With other specified complications
0.000 0.437 0.563
K90.9 Intestinal malabsorption, unspecified
0.000 0.437 0.563
E80.2 Other porphyria
0.000 0.444 0.556
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.444 0.555
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.444 0.555
E79.1 Lesch-Nyhan syndrome
0.000 0.444 0.555
E14.1 With ketoacidosis
0.000 0.447 0.553
E13.3 With ophthalmic complications
0.000 0.447 0.552
E88.9 Metabolic disorder, unspecified
0.000 0.451 0.549
E85.4 Organ-limited amyloidosis
0.000 0.451 0.549
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.458 0.541
E40-E46 Malnutrition
0.000 0.470 0.529
E11.6 With other specified complications
0.000 0.471 0.529
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E85.9 Amyloidosis, unspecified
0.000 0.494 0.506
E70.3 Albinism
0.000 0.501 0.499
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.506 0.494
E16.1 Other hypoglycaemia
0.000 0.507 0.493
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.510 0.490
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.510 0.490
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.510 0.490
E74.2 Disorders of galactose metabolism
0.000 0.510 0.490
E74.1 Disorders of fructose metabolism
0.000 0.510 0.490
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.510 0.490
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.512 0.488
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.512 0.488
E16.4 Abnormal secretion of gastrin
0.000 0.512 0.488
E16.3 Increased secretion of glucagon
0.000 0.512 0.488
E10.5 With peripheral circulatory complications
0.000 0.514 0.486
E88.2 Lipomatosis, not elsewhere classified
0.000 0.516 0.484
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.517 0.483
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.517 0.483
E70.2 Disorders of tyrosine metabolism
0.000 0.517 0.483
E70.1 Other hyperphenylalaninaemias
0.000 0.517 0.483
E70.0 Classical phenylketonuria
0.000 0.517 0.483
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.518 0.481
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.518 0.481
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.518 0.481
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.519 0.481
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.519 0.481
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.519 0.481
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.519 0.481
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.519 0.481
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.519 0.481
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.519 0.481
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.519 0.481
E07 Other disorders of thyroid
0.000 0.528 0.472
E71.3 Disorders of fatty-acid metabolism
0.000 0.528 0.472
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.528 0.472
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.528 0.472
E71.0 Maple-syrup-urine disease
0.000 0.528 0.472
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.528 0.472
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.528 0.472
E72.5 Disorders of glycine metabolism
0.000 0.528 0.472
E72.4 Disorders of ornithine metabolism
0.000 0.528 0.472
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.528 0.472
E72.2 Disorders of urea cycle metabolism
0.000 0.528 0.472
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.528 0.472
E72.0 Disorders of amino-acid transport
0.000 0.528 0.472
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.528 0.472
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.528 0.472
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.528 0.472
E76.2 Other mucopolysaccharidoses
0.000 0.528 0.472
E76.1 Mucopolysaccharidosis, type II
0.000 0.528 0.472
E76.0 Mucopolysaccharidosis, type I
0.000 0.528 0.472
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.528 0.472
E77.8 Other disorders of glycoprotein metabolism
0.000 0.528 0.472
E77.1 Defects in glycoprotein degradation
0.000 0.528 0.472
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.528 0.472
E88.3 Tumour lysis syndrome
0.000 0.533 0.467
E85.8 Other amyloidosis
0.000 0.538 0.462
L43 Lichen planus
0.000 0.542 0.458
E74.0 Glycogen storage disease
0.000 0.545 0.454
E73 Lactose intolerance
0.001 0.546 0.453
E10.4 With neurological complications
0.000 0.548 0.451
E75.5 Other lipid storage disorders
0.000 0.551 0.448
E75.6 Lipid storage disorder, unspecified
0.000 0.552 0.448
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.552 0.448
E75.3 Sphingolipidosis, unspecified
0.000 0.552 0.448
E75.1 Other gangliosidosis
0.000 0.552 0.448
E75.0 GM2 gangliosidosis
0.000 0.552 0.448
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.557 0.443
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.557 0.443
E06.5 Other chronic thyroiditis
0.000 0.559 0.441
L42 Pityriasis rosea
0.000 0.565 0.435
E06.1 Subacute thyroiditis
0.000 0.567 0.433
E06.4 Drug-induced thyroiditis
0.000 0.567 0.433
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.567 0.433
E06.0 Acute thyroiditis
0.000 0.567 0.433
E03 Other hypothyroidism
0.000 0.568 0.432
E50-E64 Other nutritional deficiencies
0.000 0.576 0.424
E65-E68 Obesity and other hyperalimentation
0.000 0.578 0.422
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.584 0.416
E75.2 Other sphingolipidosis
0.000 0.585 0.415
E84.8 Cystic fibrosis with other manifestations
0.000 0.586 0.413
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.586 0.413
E84.9 Cystic fibrosis, unspecified
0.000 0.590 0.410
E06.9 Thyroiditis, unspecified
0.000 0.592 0.408
L43.9 Lichen planus, unspecified
0.000 0.594 0.406
L44 Other papulosquamous disorders
0.000 0.594 0.406
L41 Parapsoriasis
0.000 0.594 0.406
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.594 0.406
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.596 0.404
E85.3 Secondary systemic amyloidosis
0.000 0.611 0.389
E06.3 Autoimmune thyroiditis
0.000 0.615 0.385
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.620 0.380
E45 Retarded development following protein-energy malnutrition
0.000 0.620 0.380
E43 Unspecified severe protein-energy malnutrition
0.000 0.620 0.380
E42 Marasmic kwashiorkor
0.000 0.620 0.380
E41 Nutritional marasmus
0.000 0.620 0.380
E40 Kwashiorkor
0.000 0.620 0.380
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.652 0.348
E07.8 Other specified disorders of thyroid
0.000 0.656 0.344
E07.1 Dyshormogenetic goitre
0.000 0.661 0.338
E07.0 Hypersecretion of calcitonin
0.000 0.661 0.338
E89.3 Postprocedural hypopituitarism
0.000 0.663 0.337
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.663 0.337
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.663 0.337
E61 Deficiency of other nutrient elements
0.000 0.667 0.333
E89.1 Postprocedural hypoinsulinaemia
0.000 0.669 0.331
L43.3 Subacute (active) lichen planus
0.000 0.671 0.328
L43.2 Lichenoid drug reaction
0.000 0.671 0.328
L43.1 Bullous lichen planus
0.000 0.671 0.328
L43.0 Hypertrophic lichen planus
0.000 0.671 0.328
E73.8 Other lactose intolerance
0.001 0.674 0.325
E73.1 Secondary lactase deficiency
0.001 0.674 0.325
E73.0 Congenital lactase deficiency
0.001 0.674 0.325
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.682 0.317
E03.8 Other specified hypothyroidism
0.000 0.683 0.317
E03.5 Myxoedema coma
0.000 0.690 0.310
E03.4 Atrophy of thyroid (acquired)
0.000 0.690 0.310
E03.3 Postinfectious hypothyroidism
0.000 0.690 0.310
E89.4 Postprocedural ovarian failure
0.000 0.691 0.309
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.693 0.307
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.696 0.304
E63 Other nutritional deficiencies
0.000 0.696 0.304
E50 Vitamin A deficiency
0.000 0.696 0.304
E60 Dietary zinc deficiency
0.000 0.696 0.304
E59 Dietary selenium deficiency
0.000 0.696 0.304
E52 Niacin deficiency [pellagra]
0.000 0.696 0.304
E67 Other hyperalimentation
0.000 0.697 0.303
E68 Sequelae of hyperalimentation
0.000 0.697 0.303
E55 Vitamin D deficiency
0.000 0.698 0.302
G56.0 Carpal tunnel syndrome
0.000 0.700 0.300
E89.5 Postprocedural testicular hypofunction
0.000 0.700 0.299
E56 Other vitamin deficiencies
0.000 0.701 0.299
Z86.1 Personal history of infectious and parasitic diseases
0.000 0.701 0.299
E58 Dietary calcium deficiency
0.000 0.708 0.292
L41.9 Parapsoriasis, unspecified
0.000 0.709 0.291
L41.8 Other parapsoriasis
0.000 0.709 0.291
L41.5 Retiform parapsoriasis
0.000 0.709 0.291
L41.4 Large plaque parapsoriasis
0.000 0.709 0.291
L41.3 Small plaque parapsoriasis
0.000 0.709 0.291
L41.2 Lymphomatoid papulosis
0.000 0.709 0.291
L41.1 Pityriasis lichenoides chronica
0.000 0.709 0.291
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.709 0.291
L44.9 Papulosquamous disorder, unspecified
0.000 0.709 0.291
L44.8 Other specified papulosquamous disorders
0.000 0.709 0.291
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.709 0.291
L44.3 Lichen ruber moniliformis
0.000 0.709 0.291
L44.2 Lichen striatus
0.000 0.709 0.291
L44.1 Lichen nitidus
0.000 0.709 0.291
L44.0 Pityriasis rubra pilaris
0.000 0.709 0.291
E03.1 Congenital hypothyroidism without goitre
0.000 0.711 0.289
E51 Thiamine deficiency
0.000 0.715 0.285
E89.2 Postprocedural hypoparathyroidism
0.000 0.715 0.285
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.717 0.283
E44.1 Mild protein-energy malnutrition
0.000 0.727 0.272
E44.0 Moderate protein-energy malnutrition
0.000 0.727 0.272
L43.8 Other lichen planus
0.000 0.735 0.265
E61.2 Magnesium deficiency
0.000 0.739 0.261
E54 Ascorbic acid deficiency
0.000 0.744 0.255
E65 Localised adiposity
0.000 0.749 0.251
E61.1 Iron deficiency
0.000 0.752 0.248
E61.9 Deficiency of nutrient element, unspecified
0.000 0.761 0.239
E61.8 Deficiency of other specified nutrient elements
0.000 0.761 0.239
E61.7 Deficiency of multiple nutrient elements
0.000 0.761 0.239
E61.6 Vanadium deficiency
0.000 0.761 0.239
E61.5 Molybdenum deficiency
0.000 0.761 0.239
E61.4 Chromium deficiency
0.000 0.761 0.239
E61.3 Manganese deficiency
0.000 0.761 0.239
E61.0 Copper deficiency
0.000 0.761 0.239
E46 Unspecified protein-energy malnutrition
0.000 0.768 0.232
E50.9 Vitamin A deficiency, unspecified
0.000 0.782 0.218
E50.8 Other manifestations of vitamin A deficiency
0.000 0.782 0.218
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.782 0.218
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.782 0.218
E50.5 Vitamin A deficiency with night blindness
0.000 0.782 0.218
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.782 0.218
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.782 0.218
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.782 0.218
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.782 0.218
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.782 0.218
E63.9 Nutritional deficiency, unspecified
0.000 0.782 0.218
E63.8 Other specified nutritional deficiencies
0.000 0.782 0.218
E63.1 Imbalance of constituents of food intake
0.000 0.782 0.218
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.782 0.218
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.782 0.218
E64.8 Sequelae of other nutritional deficiencies
0.000 0.782 0.218
E64.3 Sequelae of rickets
0.000 0.782 0.218
E64.2 Sequelae of vitamin C deficiency
0.000 0.782 0.218
E64.1 Sequelae of vitamin A deficiency
0.000 0.782 0.218
E64.0 Sequelae of protein-energy malnutrition
0.000 0.782 0.218
E67.8 Other specified hyperalimentation
0.000 0.783 0.217
E67.3 Hypervitaminosis D
0.000 0.783 0.217
E67.2 Megavitamin-B6 syndrome
0.000 0.783 0.217
E67.1 Hypercarotenaemia
0.000 0.783 0.217
E67.0 Hypervitaminosis A
0.000 0.783 0.217
E55.0 Rickets, active
0.000 0.783 0.217
E55.9 Vitamin D deficiency, unspecified
0.000 0.785 0.215
E56.9 Vitamin deficiency, unspecified
0.000 0.785 0.215
E56.8 Deficiency of other vitamins
0.000 0.785 0.215
E56.0 Deficiency of vitamin E
0.000 0.785 0.215
E56.1 Deficiency of vitamin K
0.000 0.790 0.210
E51.9 Thiamine deficiency, unspecified
0.000 0.795 0.204
E51.8 Other manifestations of thiamine deficiency
0.000 0.795 0.204
E51.1 Beriberi
0.000 0.795 0.204
E51.2 Wernicke's encephalopathy
0.000 0.814 0.186
E11.3 With ophthalmic complications
0.000 0.814 0.186
E53 Deficiency of other B group vitamins
0.000 0.838 0.162
E66 Obesity
0.000 0.839 0.161
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.853 0.147
G56 Mononeuropathies of upper limb
0.000 0.858 0.142
E89.0 Postprocedural hypothyroidism
0.000 0.864 0.136
E07.9 Disorder of thyroid, unspecified
0.000 0.874 0.126
G56.9 Mononeuropathy of upper limb, unspecified
0.000 0.878 0.122
E73.9 Lactose intolerance, unspecified
0.002 0.878 0.120
G56.8 Other mononeuropathies of upper limb
0.000 0.881 0.119
E53.1 Pyridoxine deficiency
0.000 0.883 0.116
E53.0 Riboflavin deficiency
0.000 0.883 0.116
E66.1 Drug-induced obesity
0.000 0.885 0.115
G56.3 Lesion of radial nerve
0.000 0.885 0.115
G56.4 Causalgia
0.000 0.903 0.097
E66.0 Obesity due to excess calories
0.000 0.904 0.096
G56.1 Other lesions of median nerve
0.000 0.908 0.092
E20-E35 Disorders of other endocrine glands
0.000 0.911 0.089
E53.9 Vitamin B deficiency, unspecified
0.000 0.912 0.088
E86 Volume depletion
0.000 0.923 0.077
E24 Cushing's syndrome
0.000 0.927 0.073
E25 Adrenogenital disorders
0.000 0.928 0.072
E23 Hypofunction and other disorders of pituitary gland
0.000 0.935 0.065
E24.0 Pituitary-dependent Cushing's disease
0.000 0.936 0.064
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.936 0.064
E32 Diseases of thymus
0.000 0.936 0.064
E30 Disorders of puberty, not elsewhere classified
0.000 0.936 0.064
K90-K93 Other diseases of the digestive system
0.000 0.937 0.062
E24.2 Drug-induced Cushing's syndrome
0.000 0.939 0.061
E31 Polyglandular dysfunction
0.000 0.939 0.061
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.941 0.059
E04 Other non-toxic goitre
0.001 0.942 0.057
E26 Hyperaldosteronism
0.000 0.944 0.056
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.944 0.056
E23.7 Disorder of pituitary gland, unspecified
0.000 0.944 0.056
E23.6 Other disorders of pituitary gland
0.000 0.947 0.053
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.948 0.052
E24.3 Ectopic ACTH syndrome
0.000 0.948 0.052
E24.1 Nelson's syndrome
0.000 0.948 0.052
E22 Hyperfunction of pituitary gland
0.000 0.948 0.052
E25.9 Adrenogenital disorder, unspecified
0.000 0.948 0.051
E25.8 Other adrenogenital disorders
0.000 0.948 0.051
E20 Hypoparathyroidism
0.000 0.949 0.051
E24.8 Other Cushing's syndrome
0.000 0.951 0.048
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.953 0.047
E23.1 Drug-induced hypopituitarism
0.000 0.953 0.047
E28 Ovarian dysfunction
0.000 0.953 0.047
E29 Testicular dysfunction
0.000 0.953 0.047
E53.8 Deficiency of other specified B group vitamins
0.000 0.953 0.047
E30.9 Disorder of puberty, unspecified
0.000 0.954 0.046
E30.8 Other disorders of puberty
0.000 0.954 0.046
E30.1 Precocious puberty
0.000 0.954 0.046
E30.0 Delayed puberty
0.000 0.954 0.046
E32.9 Disease of thymus, unspecified
0.000 0.954 0.046
E32.8 Other diseases of thymus
0.000 0.954 0.046
E32.1 Abscess of thymus
0.000 0.954 0.046
E32.0 Persistent hyperplasia of thymus
0.000 0.954 0.046
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.954 0.046
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.954 0.046
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.954 0.046
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.955 0.045
E31.9 Polyglandular dysfunction, unspecified
0.000 0.956 0.044
E31.8 Other polyglandular dysfunction
0.000 0.956 0.044
E31.1 Polyglandular hyperfunction
0.000 0.956 0.044
E21.2 Other hyperparathyroidism
0.000 0.957 0.043
E21.3 Hyperparathyroidism, unspecified
0.000 0.957 0.043
E34 Other endocrine disorders
0.000 0.957 0.042
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.958 0.042
E83 Disorders of mineral metabolism
0.002 0.958 0.040
E04.8 Other specified non-toxic goitre
0.001 0.958 0.041
E22.1 Hyperprolactinaemia
0.000 0.958 0.041
E26.8 Other hyperaldosteronism
0.000 0.959 0.041
E26.1 Secondary hyperaldosteronism
0.000 0.959 0.041
E21.4 Other specified disorders of parathyroid gland
0.000 0.959 0.041
E31.0 Autoimmune polyglandular failure
0.000 0.960 0.040
E26.9 Hyperaldosteronism, unspecified
0.000 0.960 0.040
E23.0 Hypopituitarism
0.000 0.960 0.040
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.962 0.038
E66.8 Other obesity
0.000 0.962 0.038
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.962 0.037
E22.8 Other hyperfunction of pituitary gland
0.000 0.962 0.037
E20.8 Other hypoparathyroidism
0.000 0.963 0.037
E20.1 Pseudohypoparathyroidism
0.000 0.963 0.037
E20.0 Idiopathic hypoparathyroidism
0.000 0.963 0.037
E04.0 Non-toxic diffuse goitre
0.001 0.964 0.035
E28.9 Ovarian dysfunction, unspecified
0.000 0.966 0.034
E28.8 Other ovarian dysfunction
0.000 0.966 0.034
E28.1 Androgen excess
0.000 0.966 0.034
E28.0 Oestrogen excess
0.000 0.966 0.034
E24.9 Cushing's syndrome, unspecified
0.000 0.966 0.034
E26.0 Primary hyperaldosteronism
0.000 0.966 0.034
E29.9 Testicular dysfunction, unspecified
0.000 0.966 0.034
E29.8 Other testicular dysfunction
0.000 0.966 0.034
E29.0 Testicular hyperfunction
0.000 0.966 0.034
E23.2 Diabetes insipidus
0.000 0.967 0.033
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.967 0.032
K93.1 Megacolon in Chagas' disease
0.000 0.967 0.032
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.967 0.032
E34.8 Other specified endocrine disorders
0.000 0.967 0.032
E22.0 Acromegaly and pituitary gigantism
0.000 0.968 0.032
E28.3 Primary ovarian failure
0.000 0.969 0.031
E34.5 Androgen resistance syndrome
0.000 0.969 0.030
E34.4 Constitutional tall stature
0.000 0.969 0.030
E34.3 Short stature, not elsewhere classified
0.000 0.969 0.030
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.969 0.030
E34.1 Other hypersecretion of intestinal hormones
0.000 0.969 0.030
E83.8 Other disorders of mineral metabolism
0.001 0.970 0.029
E83.2 Disorders of zinc metabolism
0.001 0.970 0.029
E83.0 Disorders of copper metabolism
0.001 0.970 0.029
E27 Other disorders of adrenal gland
0.000 0.971 0.029
E83.9 Disorder of mineral metabolism, unspecified
0.001 0.972 0.027
K91.4 Colostomy and enterostomy malfunction
0.026 0.973 0.000
E21.0 Primary hyperparathyroidism
0.000 0.974 0.026
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.975 0.025
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.975 0.025
E34.9 Endocrine disorder, unspecified
0.000 0.976 0.024
E20.9 Hypoparathyroidism, unspecified
0.001 0.976 0.023
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.977 0.023
E28.2 Polycystic ovarian syndrome
0.000 0.978 0.022
E27.5 Adrenomedullary hyperfunction
0.000 0.979 0.021
E27.0 Other adrenocortical overactivity
0.000 0.979 0.021
E27.9 Disorder of adrenal gland, unspecified
0.000 0.979 0.021
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.982 0.018
E27.8 Other specified disorders of adrenal gland
0.000 0.982 0.018
Z88.4 Personal history of allergy to anaesthetic agent
0.018 0.982 0.000
E34.0 Carcinoid syndrome
0.001 0.983 0.017
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.001 0.983 0.016
E29.1 Testicular hypofunction
0.000 0.984 0.016
M07.3 Other psoriatic arthropathies
0.000 0.984 0.016
E03.9 Hypothyroidism, unspecified
0.000 0.984 0.016
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.984 0.016
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.984 0.016
G56.2 Lesion of ulnar nerve
0.000 0.984 0.016
C16.9 Stomach, unspecified
0.000 0.984 0.016
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.985 0.015
C85.1 B-cell lymphoma, unspecified
0.000 0.985 0.015
E27.1 Primary adrenocortical insufficiency
0.000 0.985 0.015
E83.4 Disorders of magnesium metabolism
0.001 0.985 0.014
K91.1 Postgastric surgery syndromes
0.000 0.985 0.015
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.986 0.014
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.986 0.014
C83.3 Large cell (diffuse)
0.000 0.986 0.014
K91.9 Postprocedural disorder of digestive system, unspecified
0.001 0.986 0.013
E83.3 Disorders of phosphorus metabolism
0.002 0.986 0.012
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.987 0.013
E83.5 Disorders of calcium metabolism
0.000 0.987 0.013
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.987 0.013
E27.2 Addisonian crisis
0.000 0.987 0.012
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.987 0.012
R94.3 Abnormal results of cardiovascular function studies
0.013 0.987 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.987 0.012
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.988 0.012
K91.5 Postcholecystectomy syndrome
0.001 0.988 0.011
M07.38 Other psoriatic arthropathies (Other)
0.000 0.988 0.012
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.988 0.012
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.988 0.012
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.988 0.012
C85.0 Lymphosarcoma
0.000 0.988 0.012
K91.2 Postsurgical malabsorption, not elsewhere classified
0.001 0.989 0.011
E04.9 Non-toxic goitre, unspecified
0.000 0.989 0.011
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.989 0.010
E04.1 Non-toxic single thyroid nodule
0.001 0.989 0.010
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.990 0.010
H71 Cholesteatoma of middle ear
0.000 0.990 0.010
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.990 0.010
C77.1 Intrathoracic lymph nodes
0.000 0.990 0.010
C16 Malignant neoplasm of stomach
0.000 0.992 0.008

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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