TreeWAS – Variant ID: rs2239800

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
E10.9 Without complications	0.000	0.020	0.980
E10 Insulin-dependent diabetes mellitus	0.001	0.030	0.969
L40.0 Psoriasis vulgaris	0.938	0.062	0.000
E10.3 With ophthalmic complications	0.000	0.077	0.923
E10.1 With ketoacidosis	0.000	0.087	0.913
E10.4 With neurological complications	0.000	0.147	0.853
L40.8 Other psoriasis	0.816	0.184	0.000
E11.9 Without complications	0.720	0.280	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
L40.1 Generalised pustular psoriasis	0.717	0.283	0.000
E11 Non-insulin-dependent diabetes mellitus	0.715	0.284	0.000
E10.5 With peripheral circulatory complications	0.000	0.294	0.706
E10.8 With unspecified complications	0.001	0.305	0.695
E10.7 With multiple complications	0.001	0.305	0.695
E10.6 With other specified complications	0.001	0.305	0.695
E10.2 With renal complications	0.001	0.305	0.695
E11.3 With ophthalmic complications	0.689	0.311	0.000
E11.2 With renal complications	0.679	0.321	0.000
E10.0 With coma	0.001	0.324	0.676
I60-I69 Cerebrovascular diseases	0.632	0.368	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.371	0.629
M06.9 Rheumatoid arthritis, unspecified	0.000	0.372	0.628
I64 Stroke, not specified as haemorrhage or infarction	0.624	0.376	0.000
I61 Intracerebral haemorrhage	0.616	0.384	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.389	0.611
L40-L45 Papulosquamous disorders	0.611	0.389	0.000
E10-E14 Diabetes mellitus	0.545	0.392	0.063
K90 Intestinal malabsorption	0.004	0.396	0.600
C44 Other malignant neoplasms of skin	0.577	0.423	0.000
I69 Sequelae of cerebrovascular disease	0.577	0.423	0.000
C44.4 Skin of scalp and neck	0.574	0.426	0.000
E11.0 With coma	0.571	0.428	0.000
I10 Essential (primary) hypertension	0.570	0.430	0.000
Chapter IX Diseases of the circulatory system	0.568	0.432	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.566	0.434	0.000
I10-I15 Hypertensive diseases	0.566	0.434	0.000
E11.8 With unspecified complications	0.562	0.437	0.000
I67 Other cerebrovascular diseases	0.558	0.442	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.454	0.546
C44.7 Skin of lower limb, including hip	0.546	0.454	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.455	0.545
I61.5 Intracerebral haemorrhage, intraventricular	0.545	0.455	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.458	0.542
I60 Subarachnoid haemorrhage	0.534	0.466	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.531	0.469	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.527	0.473	0.000
E11.1 With ketoacidosis	0.524	0.475	0.000
C44.5 Skin of trunk	0.524	0.476	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.480	0.520
C44.3 Skin of other and unspecified parts of face	0.516	0.484	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.516	0.484	0.000
E11.7 With multiple complications	0.513	0.487	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.508	0.492	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.502	0.495	0.003
K90.9 Intestinal malabsorption, unspecified	0.002	0.497	0.501
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.502	0.498	0.000
I27 Other pulmonary heart diseases	0.500	0.500	0.000
E20-E35 Disorders of other endocrine glands	0.498	0.502	0.000
C44.2 Skin of ear and external auricular canal	0.497	0.503	0.000
C44.0 Skin of lip	0.497	0.503	0.000
I67.8 Other specified cerebrovascular diseases	0.495	0.505	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.494	0.506	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.481	0.519	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.474	0.526	0.000
I11 Hypertensive heart disease	0.474	0.526	0.000
E11.6 With other specified complications	0.473	0.526	0.000
I27.2 Other secondary pulmonary hypertension	0.473	0.527	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.460	0.540	0.000
I28 Other diseases of pulmonary vessels	0.459	0.541	0.000
# Top node	0.458	0.542	0.000
I67.1 Cerebral aneurysm, nonruptured	0.456	0.544	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.454	0.546	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.453	0.547	0.000
I67.2 Cerebral atherosclerosis	0.453	0.547	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.550	0.450
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.448	0.552	0.000
I61.8 Other intracerebral haemorrhage	0.448	0.552	0.000
Chapter II Neoplasms	0.447	0.553	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.003	0.553	0.444
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.445	0.555	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.556	0.444
E21.3 Hyperparathyroidism, unspecified	0.442	0.558	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.442	0.558	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.442	0.558	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.442	0.558	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.442	0.558	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.441	0.559	0.000
E11.4 With neurological complications	0.440	0.559	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.439	0.561	0.000
L44 Other papulosquamous disorders	0.438	0.562	0.000
L41 Parapsoriasis	0.438	0.562	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.438	0.562	0.000
L42 Pityriasis rosea	0.437	0.563	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.437	0.563	0.000
E12 Malnutrition-related diabetes mellitus	0.391	0.564	0.045
K90.8 Other intestinal malabsorption	0.003	0.567	0.430
K90.3 Pancreatic steatorrhoea	0.003	0.567	0.430
K90.2 Blind loop syndrome, not elsewhere classified	0.003	0.567	0.430
K90.1 Tropical sprue	0.003	0.567	0.430
E27 Other disorders of adrenal gland	0.431	0.569	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.570	0.430
C43 Malignant melanoma of skin	0.421	0.579	0.000
E21.0 Primary hyperparathyroidism	0.419	0.581	0.000
C44.8 Overlapping lesion of skin	0.414	0.586	0.000
I05-I09 Chronic rheumatic heart diseases	0.413	0.587	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.408	0.592	0.000
Q50-Q56 Congenital malformations of genital organs	0.408	0.592	0.000
I00-I02 Acute rheumatic fever	0.407	0.592	0.000
I28.8 Other specified diseases of pulmonary vessels	0.407	0.593	0.000
I13 Hypertensive heart and renal disease	0.406	0.594	0.000
E20 Hypoparathyroidism	0.404	0.596	0.000
I27.0 Primary pulmonary hypertension	0.404	0.596	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.403	0.597	0.000
Q80-Q89 Other congenital malformations	0.403	0.597	0.000
E13 Other specified diabetes mellitus	0.358	0.598	0.045
I67.7 Cerebral arteritis, not elsewhere classified	0.400	0.600	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.400	0.600	0.000
I67.5 Moyamoya disease	0.400	0.600	0.000
I67.4 Hypertensive encephalopathy	0.400	0.600	0.000
I67.3 Progressive vascular leukoencephalopathy	0.400	0.600	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.400	0.600	0.000
I65.2 Occlusion and stenosis of carotid artery	0.395	0.605	0.000
I69.3 Sequelae of cerebral infarction	0.392	0.608	0.000
I60.8 Other subarachnoid haemorrhage	0.392	0.608	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.612	0.387
C43.3 Malignant melanoma of other and unspecified parts of face	0.387	0.613	0.000
E23 Hypofunction and other disorders of pituitary gland	0.385	0.615	0.000
E34 Other endocrine disorders	0.384	0.616	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.384	0.616	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.383	0.617	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.383	0.617	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.383	0.617	0.000
E24 Cushing's syndrome	0.383	0.617	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.381	0.619	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.380	0.620	0.000
I15 Secondary hypertension	0.377	0.622	0.000
I62 Other nontraumatic intracranial haemorrhage	0.375	0.624	0.000
I27.8 Other specified pulmonary heart diseases	0.366	0.634	0.000
Q83 Congenital malformations of breast	0.366	0.634	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.365	0.635	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.364	0.636	0.000
E11.5 With peripheral circulatory complications	0.362	0.637	0.001
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.361	0.639	0.000
I27.1 Kyphoscoliotic heart disease	0.359	0.641	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.358	0.642	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.357	0.642	0.000
E32 Diseases of thymus	0.357	0.642	0.000
E31 Polyglandular dysfunction	0.357	0.642	0.000
E30 Disorders of puberty, not elsewhere classified	0.357	0.642	0.000
E25 Adrenogenital disorders	0.357	0.642	0.000
E29 Testicular dysfunction	0.357	0.643	0.000
Q54 Hypospadias	0.356	0.644	0.000
Chapter V Mental and behavioural disorders	0.356	0.644	0.000
E26 Hyperaldosteronism	0.356	0.644	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.354	0.646	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.354	0.646	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.354	0.646	0.000
I65.1 Occlusion and stenosis of basilar artery	0.354	0.646	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.354	0.646	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.354	0.646	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.353	0.647	0.000
D00-D09 In situ neoplasms	0.351	0.649	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.350	0.650	0.000
I95 Hypotension	0.348	0.652	0.000
J47 Bronchiectasis	0.000	0.654	0.346
E21.4 Other specified disorders of parathyroid gland	0.345	0.655	0.000
E21.2 Other hyperparathyroidism	0.345	0.655	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.345	0.655	0.000
Q52 Other congenital malformations of female genitalia	0.345	0.655	0.000
C15-C26 Malignant neoplasms of digestive organs	0.345	0.655	0.000
E28 Ovarian dysfunction	0.342	0.657	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.340	0.659	0.000
L50-L54 Urticaria and erythema	0.340	0.660	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.340	0.660	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.340	0.660	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.340	0.660	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.340	0.660	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.340	0.660	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.340	0.660	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.340	0.660	0.000
J40-J47 Chronic lower respiratory diseases	0.000	0.662	0.338
M06 Other rheumatoid arthritis	0.047	0.663	0.290
I07 Rheumatic tricuspid valve diseases	0.337	0.663	0.000
E20.9 Hypoparathyroidism, unspecified	0.337	0.663	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.336	0.663	0.000
E40-E46 Malnutrition	0.331	0.666	0.002
J44 Other chronic obstructive pulmonary disease	0.000	0.666	0.334
Q83.8 Other congenital malformations of breast	0.333	0.666	0.000
E27.8 Other specified disorders of adrenal gland	0.333	0.667	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.667	0.333
C43.9 Malignant melanoma of skin, unspecified	0.332	0.668	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.331	0.669	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.331	0.669	0.000
Q60-Q64 Congenital malformations of the urinary system	0.330	0.670	0.000
L10-L14 Bullous disorders	0.330	0.670	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.330	0.670	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.329	0.671	0.000
I28.1 Aneurysm of pulmonary artery	0.329	0.671	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.329	0.671	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.329	0.671	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.329	0.671	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.328	0.671	0.000
C44.1 Skin of eyelid, including canthus	0.328	0.672	0.000
J33.9 Nasal polyp, unspecified	0.000	0.673	0.327
C60-C63 Malignant neoplasms of male genital organs	0.327	0.673	0.000
E70-E90 Metabolic disorders	0.326	0.674	0.000
E27.2 Addisonian crisis	0.325	0.674	0.000
I27.9 Pulmonary heart disease, unspecified	0.325	0.675	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.325	0.675	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.325	0.675	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.325	0.675	0.000
I68.0 Cerebral amyloid angiopathy	0.325	0.675	0.000
Q21 Congenital malformations of cardiac septa	0.322	0.677	0.000
D46 Myelodysplastic syndromes	0.322	0.678	0.000
Chapter X Diseases of the respiratory system	0.000	0.679	0.321
C64-C68 Malignant neoplasms of urinary tract	0.321	0.679	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.321	0.679	0.000
I95.9 Hypotension, unspecified	0.321	0.679	0.000
E27.9 Disorder of adrenal gland, unspecified	0.320	0.680	0.000
E22 Hyperfunction of pituitary gland	0.319	0.681	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.319	0.681	0.000
Q35-Q37 Cleft lip and cleft palate	0.319	0.681	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.319	0.681	0.000
J33 Nasal polyp	0.000	0.682	0.318
C17 Malignant neoplasm of small intestine	0.318	0.682	0.000
E27.1 Primary adrenocortical insufficiency	0.317	0.683	0.000
Q51 Congenital malformations of uterus and cervix	0.316	0.684	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.315	0.685	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.315	0.685	0.000
L41.9 Parapsoriasis, unspecified	0.314	0.686	0.000
L41.8 Other parapsoriasis	0.314	0.686	0.000
L41.5 Retiform parapsoriasis	0.314	0.686	0.000
L41.4 Large plaque parapsoriasis	0.314	0.686	0.000
L41.3 Small plaque parapsoriasis	0.314	0.686	0.000
L41.2 Lymphomatoid papulosis	0.314	0.686	0.000
L41.1 Pityriasis lichenoides chronica	0.314	0.686	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.314	0.686	0.000
L44.9 Papulosquamous disorder, unspecified	0.314	0.686	0.000
L44.8 Other specified papulosquamous disorders	0.314	0.686	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.314	0.686	0.000
L44.3 Lichen ruber moniliformis	0.314	0.686	0.000
L44.2 Lichen striatus	0.314	0.686	0.000
L44.1 Lichen nitidus	0.314	0.686	0.000
L44.0 Pityriasis rubra pilaris	0.314	0.686	0.000
Q53 Undescended testicle	0.314	0.686	0.000
C21 Malignant neoplasm of anus and anal canal	0.314	0.686	0.000
C51-C58 Malignant neoplasms of female genital organs	0.313	0.687	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.313	0.687	0.000
E12.9 Without complications	0.280	0.687	0.032
E12.8 With unspecified complications	0.280	0.687	0.032
E12.7 With multiple complications	0.280	0.687	0.032
E12.6 With other specified complications	0.280	0.687	0.032
E12.5 With peripheral circulatory complications	0.280	0.687	0.032
E12.4 With neurological complications	0.280	0.687	0.032
E12.3 With ophthalmic complications	0.280	0.687	0.032
E12.2 With renal complications	0.280	0.687	0.032
E12.1 With ketoacidosis	0.280	0.687	0.032
E12.0 With coma	0.280	0.687	0.032
E24.0 Pituitary-dependent Cushing's disease	0.310	0.690	0.000
E27.5 Adrenomedullary hyperfunction	0.309	0.691	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.309	0.691	0.000
E27.0 Other adrenocortical overactivity	0.309	0.691	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.309	0.691	0.000
D04 Carcinoma in situ of skin	0.308	0.692	0.000
Q76 Congenital malformations of spine and bony thorax	0.307	0.693	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.306	0.694	0.000
E14 Unspecified diabetes mellitus	0.284	0.694	0.022
E65-E68 Obesity and other hyperalimentation	0.305	0.694	0.001
C25 Malignant neoplasm of pancreas	0.306	0.694	0.000
C43.4 Malignant melanoma of scalp and neck	0.304	0.696	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.303	0.697	0.000
C43.8 Overlapping malignant melanoma of skin	0.302	0.698	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.302	0.698	0.000
C43.0 Malignant melanoma of lip	0.302	0.698	0.000
E23.7 Disorder of pituitary gland, unspecified	0.302	0.698	0.000
Chapter XX External causes of morbidity and mortality	0.301	0.699	0.000
I05 Rheumatic mitral valve diseases	0.300	0.700	0.000
J30-J39 Other diseases of upper respiratory tract	0.000	0.701	0.299
I99 Other and unspecified disorders of circulatory system	0.298	0.701	0.000
J00-J06 Acute upper respiratory infections	0.000	0.702	0.297
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.295	0.703	0.003
E86 Volume depletion	0.297	0.703	0.000
Q54.9 Hypospadias, unspecified	0.296	0.703	0.000
I09 Other rheumatic heart diseases	0.296	0.704	0.000
I06 Rheumatic aortic valve diseases	0.296	0.704	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.296	0.704	0.000
J60-J70 Lung diseases due to external agents	0.000	0.705	0.295
Q54.0 Hypospadias, balanic	0.294	0.705	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.294	0.706	0.000
L43 Lichen planus	0.293	0.706	0.001
Q89 Other congenital malformations, not elsewhere classified	0.294	0.706	0.000
E23.0 Hypopituitarism	0.293	0.707	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.292	0.707	0.000
Q55 Other congenital malformations of male genital organs	0.292	0.707	0.000
I02 Rheumatic chorea	0.292	0.708	0.000
I01 Rheumatic fever with heart involvement	0.292	0.708	0.000
I00 Rheumatic fever without mention of heart involvement	0.292	0.708	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.292	0.708	0.000
C32 Malignant neoplasm of larynx	0.292	0.708	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.291	0.709	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.291	0.709	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.291	0.709	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.291	0.709	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.291	0.709	0.000
E20.8 Other hypoparathyroidism	0.290	0.710	0.000
E20.1 Pseudohypoparathyroidism	0.290	0.710	0.000
E20.0 Idiopathic hypoparathyroidism	0.290	0.710	0.000
F60-F69 Disorders of adult personality and behaviour	0.290	0.710	0.000
E34.8 Other specified endocrine disorders	0.289	0.710	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.289	0.711	0.000
Q84 Other congenital malformations of integument	0.289	0.711	0.000
Q81 Epidermolysis bullosa	0.289	0.711	0.000
Q80 Congenital ichthyosis	0.289	0.711	0.000
E13.8 With unspecified complications	0.256	0.711	0.032
E13.7 With multiple complications	0.256	0.711	0.032
E13.6 With other specified complications	0.256	0.711	0.032
E13.5 With peripheral circulatory complications	0.256	0.711	0.032
E13.4 With neurological complications	0.256	0.711	0.032
E13.3 With ophthalmic complications	0.256	0.711	0.032
E13.2 With renal complications	0.256	0.711	0.032
E13.1 With ketoacidosis	0.256	0.711	0.032
E13.0 With coma	0.256	0.711	0.032
J90-J94 Other diseases of pleura	0.000	0.712	0.288
W00-W19 Falls	0.287	0.713	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.286	0.714	0.000
E34.0 Carcinoid syndrome	0.286	0.714	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.714	0.286
E78.0 Pure hypercholesterolaemia	0.286	0.714	0.000
Q85 Phakomatoses, not elsewhere classified	0.285	0.715	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.284	0.716	0.000
Q52.1 Doubling of vagina	0.284	0.716	0.000
Q00-Q07 Congenital malformations of the nervous system	0.283	0.717	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.283	0.717	0.000
I07.1 Tricuspid insufficiency	0.283	0.717	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.281	0.718	0.000
F30-F39 Mood [affective] disorders	0.281	0.719	0.000
Q82 Other congenital malformations of skin	0.281	0.719	0.000
Q83.1 Accessory breast	0.281	0.719	0.000
E34.9 Endocrine disorder, unspecified	0.281	0.719	0.000
C62 Malignant neoplasm of testis	0.281	0.719	0.000
I15.9 Seconday hypertension, unspecified	0.279	0.721	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.000	0.721	0.279
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.278	0.722	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.277	0.723	0.000
C25.0 Head of pancreas	0.276	0.724	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.276	0.724	0.000
E23.1 Drug-induced hypopituitarism	0.276	0.724	0.000
E34.5 Androgen resistance syndrome	0.276	0.724	0.000
E34.4 Constitutional tall stature	0.276	0.724	0.000
E34.3 Short stature, not elsewhere classified	0.276	0.724	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.276	0.724	0.000
E34.1 Other hypersecretion of intestinal hormones	0.276	0.724	0.000
E88 Other metabolic disorders	0.276	0.724	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.276	0.724	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.276	0.724	0.000
Q21.0 Ventricular septal defect	0.275	0.725	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.275	0.725	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.275	0.725	0.000
E24.8 Other Cushing's syndrome	0.274	0.725	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.274	0.725	0.000
E24.3 Ectopic ACTH syndrome	0.274	0.725	0.000
E24.2 Drug-induced Cushing's syndrome	0.274	0.725	0.000
E24.1 Nelson's syndrome	0.274	0.725	0.000
J33.0 Polyp of nasal cavity	0.000	0.726	0.274
D07.1 Vulva	0.274	0.726	0.000
Q25 Congenital malformations of great arteries	0.274	0.726	0.000
Q21.1 Atrial septal defect	0.274	0.726	0.000
Q52.5 Fusion of labia	0.272	0.728	0.000
C17.1 Jejunum	0.272	0.728	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.272	0.728	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.271	0.729	0.000
I15.8 Other secondary hypertension	0.271	0.729	0.000
I15.2 Hypertension secondary to endocrine disorders	0.271	0.729	0.000
I15.0 Renovascular hypertension	0.271	0.729	0.000
C21.1 Anal canal	0.270	0.730	0.000
I62.1 Nontraumatic extradural haemorrhage	0.269	0.731	0.000
Q76.0 Spina bifida occulta	0.269	0.731	0.000
J92 Pleural plaque	0.000	0.731	0.269
E23.6 Other disorders of pituitary gland	0.268	0.732	0.000
L52 Erythema nodosum	0.268	0.732	0.000
E23.2 Diabetes insipidus	0.267	0.733	0.000
J03 Acute tonsillitis	0.000	0.733	0.267
J06.9 Acute upper respiratory infection, unspecified	0.000	0.734	0.266
J69 Pneumonitis due to solids and liquids	0.000	0.734	0.266
Q24 Other congenital malformations of heart	0.265	0.734	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.265	0.735	0.000
F80-F89 Disorders of psychological development	0.264	0.736	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.264	0.736	0.000
Chapter XXII Codes for special purposes	0.263	0.737	0.000
Q83.9 Congenital malformation of breast, unspecified	0.262	0.737	0.000
Q83.3 Accessory nipple	0.262	0.737	0.000
Q83.2 Absent nipple	0.262	0.737	0.000
Q83.0 Congenital absence of breast with absent nipple	0.262	0.737	0.000
C17.2 Ileum	0.262	0.738	0.000
C51 Malignant neoplasm of vulva	0.262	0.738	0.000
E50-E64 Other nutritional deficiencies	0.260	0.738	0.002
Q78 Other osteochondrodysplasias	0.262	0.738	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.262	0.738	0.000
Q75 Other congenital malformations of skull and face bones	0.262	0.738	0.000
Q74 Other congenital malformations of limb(s)	0.262	0.738	0.000
Q73 Reduction defects of unspecified limb	0.262	0.738	0.000
Q72 Reduction defects of lower limb	0.262	0.738	0.000
Q71 Reduction defects of upper limb	0.262	0.738	0.000
Q70 Syndactyly	0.262	0.738	0.000
Q69 Polydactyly	0.262	0.738	0.000
Q68 Other congenital musculoskeletal deformities	0.262	0.738	0.000
Q65 Congenital deformities of hip	0.262	0.738	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.262	0.738	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.261	0.738	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.261	0.739	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.261	0.739	0.000
I95.0 Idiopathic hypotension	0.260	0.740	0.000
Q63 Other congenital malformations of kidney	0.260	0.740	0.000
E28.3 Primary ovarian failure	0.260	0.740	0.000
E24.9 Cushing's syndrome, unspecified	0.259	0.741	0.000
D07.5 Prostate	0.258	0.742	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.742	0.258
D04.3 Skin of other and unspecified parts of face	0.258	0.742	0.000
Q64 Other congenital malformations of urinary system	0.258	0.742	0.000
Q26 Congenital malformations of great veins	0.257	0.743	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.257	0.743	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.257	0.743	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.257	0.743	0.000
E25.9 Adrenogenital disorder, unspecified	0.256	0.743	0.000
E25.8 Other adrenogenital disorders	0.256	0.743	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.256	0.743	0.000
E30.9 Disorder of puberty, unspecified	0.256	0.743	0.000
E30.8 Other disorders of puberty	0.256	0.743	0.000
E30.1 Precocious puberty	0.256	0.743	0.000
E30.0 Delayed puberty	0.256	0.743	0.000
E31.9 Polyglandular dysfunction, unspecified	0.256	0.743	0.000
E31.8 Other polyglandular dysfunction	0.256	0.743	0.000
E31.1 Polyglandular hyperfunction	0.256	0.743	0.000
E31.0 Autoimmune polyglandular failure	0.256	0.743	0.000
E32.9 Disease of thymus, unspecified	0.256	0.743	0.000
E32.8 Other diseases of thymus	0.256	0.743	0.000
E32.1 Abscess of thymus	0.256	0.743	0.000
E32.0 Persistent hyperplasia of thymus	0.256	0.743	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.256	0.743	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.256	0.743	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.256	0.743	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.256	0.743	0.000
E29.9 Testicular dysfunction, unspecified	0.256	0.744	0.000
E29.8 Other testicular dysfunction	0.256	0.744	0.000
E29.0 Testicular hyperfunction	0.256	0.744	0.000
E29.1 Testicular hypofunction	0.256	0.744	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.256	0.744	0.000
I67.9 Cerebrovascular disease, unspecified	0.256	0.744	0.000
Q54.8 Other hypospadias	0.256	0.744	0.000
Q54.4 Congenital chordee	0.256	0.744	0.000
Q54.3 Hypospadias, perineal	0.256	0.744	0.000
Q54.2 Hypospadias, penoscrotal	0.256	0.744	0.000
Q54.1 Hypospadias, penile	0.256	0.744	0.000
I26 Pulmonary embolism	0.256	0.744	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.255	0.744	0.000
F70-F79 Mental retardation	0.255	0.744	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.255	0.744	0.000
E26.9 Hyperaldosteronism, unspecified	0.255	0.745	0.000
E26.8 Other hyperaldosteronism	0.255	0.745	0.000
E26.1 Secondary hyperaldosteronism	0.255	0.745	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.255	0.745	0.000
C21.0 Anus, unspecified	0.255	0.745	0.000
E13.9 Without complications	0.223	0.745	0.032
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.254	0.746	0.000
E26.0 Primary hyperaldosteronism	0.254	0.746	0.000
J33.8 Other polyp of sinus	0.000	0.746	0.254
D41.0 Kidney	0.253	0.746	0.000
D04.6 Skin of upper limb, including shoulder	0.253	0.747	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.253	0.747	0.000
Q51.3 Bicornate uterus	0.252	0.748	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.252	0.748	0.000
Q27 Other congenital malformations of peripheral vascular system	0.251	0.749	0.000
F99-F99 Unspecified mental disorder	0.251	0.749	0.000
C32.0 Glottis	0.251	0.749	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.251	0.749	0.000
C17.0 Duodenum	0.250	0.750	0.000
C60 Malignant neoplasm of penis	0.250	0.750	0.000
M06.0 Seronegative rheumatoid arthritis	0.024	0.750	0.225
I95.8 Other hypotension	0.249	0.750	0.000
L50 Urticaria	0.249	0.751	0.000
E22.0 Acromegaly and pituitary gigantism	0.249	0.751	0.000
X50-X57 Overexertion, travel and privation	0.248	0.751	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.248	0.752	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.248	0.752	0.000
C62.9 Testis, unspecified	0.248	0.752	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.752	0.248
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.248	0.752	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.248	0.752	0.000
F31 Bipolar affective disorder	0.248	0.752	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.247	0.753	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.247	0.753	0.000
Q53.1 Undescended testicle, unilateral	0.247	0.753	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.247	0.753	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.247	0.753	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations