TreeWAS – Variant ID: rs2239815

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.954	0.046	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.936	0.064	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.929	0.071	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.920	0.080	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.911	0.089	0.000
T42.4 Benzodiazepines	0.907	0.093	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.904	0.096	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.870	0.130	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.839	0.161	0.000
T46.1 Calcium-channel blockers	0.838	0.162	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.837	0.163	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.816	0.184	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.805	0.195	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.778	0.222	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.752	0.248	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.744	0.256	0.000
T39.0 Salicylates	0.744	0.256	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.742	0.258	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.737	0.263	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.734	0.266	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.730	0.270	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.729	0.271	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.718	0.282	0.000
T43.2 Other and unspecified antidepressants	0.717	0.283	0.000
T43.6 Psychostimulants with abuse potential	0.715	0.285	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.708	0.292	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.707	0.293	0.000
T45.0 Antiallergic and antiemetic drugs	0.707	0.293	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.705	0.295	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.702	0.298	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.694	0.306	0.000
T50.8 Diagnostic agents	0.693	0.307	0.000
T38.1 Thyroid hormones and substitutes	0.689	0.311	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.684	0.316	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.684	0.316	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.682	0.318	0.000
T47.0 Histamine H(2)-receptor antagonists	0.679	0.321	0.000
T39.1 4-Aminophenol derivatives	0.679	0.321	0.000
T50.7 Analeptics and opioid receptor antagonists	0.671	0.329	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.671	0.329	0.000
T50.5 Appetite depressants	0.671	0.329	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.671	0.329	0.000
T50.1 Loop [high-ceiling] diuretics	0.671	0.329	0.000
T50.0 Mineralocorticoids and their antagonists	0.671	0.329	0.000
T50.4 Drugs affecting uric acid metabolism	0.670	0.330	0.000
T42.0 Hydantoin derivatives	0.667	0.333	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.666	0.334	0.000
T42.3 Barbiturates	0.666	0.334	0.000
T42.2 Succinimides and oxazolidinediones	0.666	0.334	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.653	0.347	0.000
T46.7 Peripheral vasodilators	0.653	0.347	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.653	0.347	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.653	0.347	0.000
T43.9 Psychotropic drug, unspecified	0.648	0.352	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.648	0.352	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.648	0.352	0.000
T45.5 Anticoagulants	0.630	0.370	0.000
T36 Poisoning by systemic antibiotics	0.630	0.370	0.000
T39.4 Antirheumatics, not elsewhere classified	0.624	0.376	0.000
T39.2 Pyrazolone derivatives	0.624	0.376	0.000
T45.2 Vitamins, not elsewhere classified	0.614	0.386	0.000
T42.1 Iminostilbenes	0.607	0.393	0.000
T38.9 Other and unspecified hormone antagonists	0.600	0.400	0.000
T38.7 Androgens and anabolic congeners	0.600	0.400	0.000
T38.5 Other oestrogens and progestogens	0.600	0.400	0.000
T38.4 Oral contraceptives	0.600	0.400	0.000
T38.2 Antithyroid drugs	0.600	0.400	0.000
T38.0 Glucocorticoids and synthetic analogues	0.600	0.400	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.600	0.400	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.594	0.406	0.000
T47.2 Stimulant laxatives	0.594	0.406	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.590	0.410	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.587	0.413	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.585	0.415	0.000
T45.8 Other primarily systemic and haematological agents	0.585	0.415	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.585	0.415	0.000
T45.6 Fibrinolysis-affecting drugs	0.585	0.415	0.000
T45.4 Iron and its compounds	0.585	0.415	0.000
T45.3 Enzymes, not elsewhere classified	0.585	0.415	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.583	0.417	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.582	0.418	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.579	0.420	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.577	0.423	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.577	0.423	0.000
T47.7 Emetics	0.577	0.423	0.000
T47.6 Antidiarrhoeal drugs	0.577	0.423	0.000
T47.5 Digestants	0.577	0.423	0.000
T47.4 Other laxatives	0.577	0.423	0.000
T47.3 Saline and osmotic laxatives	0.577	0.423	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.570	0.430	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.561	0.438	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.543	0.457	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.534	0.466	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.534	0.466	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.534	0.466	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.534	0.466	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.534	0.466	0.000
T44.0 Anticholinesterase agents	0.534	0.466	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.529	0.471	0.000
T37.5 Antiviral drugs	0.529	0.471	0.000
T37.4 Anthelminthics	0.529	0.471	0.000
T37.3 Other antiprotozoal drugs	0.529	0.471	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.529	0.471	0.000
T37.1 Antimycobacterial drugs	0.529	0.471	0.000
T37.0 Sulphonamides	0.529	0.471	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.521	0.479	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.518	0.481	0.000
T40.6 Other and unspecified narcotics	0.509	0.491	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.503	0.496	0.000
T48.5 Anti-common-cold drugs	0.503	0.496	0.000
T48.4 Expectorants	0.503	0.496	0.000
T48.3 Antitussives	0.503	0.496	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.503	0.496	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.503	0.496	0.000
T48.0 Oxytocic drugs	0.503	0.496	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.503	0.497	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.501	0.498	0.000
T41.5 Therapeutic gases	0.491	0.509	0.000
T41.4 Anaesthetic, unspecified	0.491	0.509	0.000
T41.3 Local anaesthetics	0.491	0.509	0.000
T41.2 Other and unspecified general anaesthetics	0.491	0.509	0.000
T41.1 Intravenous anaesthetics	0.491	0.509	0.000
T41.0 Inhaled anaesthetics	0.491	0.509	0.000
T49.9 Topical agent, unspecified	0.491	0.509	0.000
T49.8 Other topical agents	0.491	0.509	0.000
T49.7 Dental drugs, topically applied	0.491	0.509	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.491	0.509	0.000
T49.5 Ophthalmological drugs and preparations	0.491	0.509	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.491	0.509	0.000
T49.3 Emollients, demulcents and protectants	0.491	0.509	0.000
T49.2 Local astringents and local detergents	0.491	0.509	0.000
T49.1 Antipruritics	0.491	0.509	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.491	0.509	0.000
T36.3 Macrolides	0.482	0.518	0.000
T36.9 Systemic antibiotic, unspecified	0.452	0.548	0.000
T36.8 Other systemic antibiotics	0.452	0.548	0.000
T36.7 Antifungal antibiotics, systemically used	0.452	0.548	0.000
T36.6 Rifamycins	0.452	0.548	0.000
T36.5 Aminoglycosides	0.452	0.548	0.000
T36.4 Tetracyclines	0.452	0.548	0.000
T36.2 Chloramphenicol group	0.452	0.548	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.452	0.548	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.431	0.569	0.000
T40.8 Lysergide [LSD]	0.431	0.569	0.000
T40.7 Cannabis (derivatives)	0.431	0.569	0.000
T40.5 Cocaine	0.431	0.569	0.000
T40.3 Methadone	0.431	0.569	0.000
T40.1 Heroin	0.431	0.569	0.000
T40.0 Opium	0.431	0.569	0.000
T36.0 Penicillins	0.350	0.649	0.000
T40.4 Other synthetic narcotics	0.326	0.674	0.000
T40.2 Other opioids	0.309	0.691	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.189	0.811	0.000
I10 Essential (primary) hypertension	0.077	0.923	0.000
S72.00 Fracture of neck of femur (closed)	0.036	0.964	0.000
I38 Endocarditis, valve unspecified	0.031	0.969	0.000
R57.2 Septic shock	0.000	0.975	0.025
I10-I15 Hypertensive diseases	0.024	0.976	0.000
R57.0 Cardiogenic shock	0.000	0.978	0.022
V18.0 Driver injured in nontraffic accident	0.000	0.978	0.022
R57 Shock, not elsewhere classified	0.000	0.978	0.022
S72.0 Fracture of neck of femur	0.022	0.978	0.000
I11 Hypertensive heart disease	0.019	0.981	0.000
I13 Hypertensive heart and renal disease	0.018	0.982	0.000
R57.1 Hypovolaemic shock	0.000	0.982	0.018
I11.9 Hypertensive heart disease without (congestive) heart failure	0.017	0.983	0.000
R57.8 Other shock	0.000	0.984	0.016
R57.9 Shock, unspecified	0.000	0.984	0.016
S72.01 Fracture of neck of femur (open)	0.016	0.984	0.000
I27.0 Primary pulmonary hypertension	0.015	0.985	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.014	0.986	0.000
I15 Secondary hypertension	0.013	0.987	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.000	0.987	0.013
I13.9 Hypertensive heart and renal disease, unspecified	0.013	0.987	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.013	0.987	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.013	0.987	0.000
I51 Complications and ill-defined descriptions of heart disease	0.013	0.987	0.000
I51.7 Cardiomegaly	0.013	0.987	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.012	0.988	0.000
I51.8 Other ill-defined heart diseases	0.012	0.988	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.988	0.012
I30 Acute pericarditis	0.012	0.988	0.000
S72 Fracture of femur	0.011	0.988	0.000
I30.9 Acute pericarditis, unspecified	0.011	0.989	0.000
I51.6 Cardiovascular disease, unspecified	0.011	0.989	0.000
I47.1 Supraventricular tachycardia	0.011	0.989	0.000
I30-I52 Other forms of heart disease	0.011	0.989	0.000
I15.0 Renovascular hypertension	0.011	0.989	0.000
I30.1 Infective pericarditis	0.010	0.990	0.000
V18.1 Passenger injured in nontraffic accident	0.000	0.990	0.010
I27 Other pulmonary heart diseases	0.010	0.990	0.000
S72.2 Subtrochanteric fracture	0.010	0.990	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.990	0.010
I51.4 Myocarditis, unspecified	0.010	0.990	0.000
I15.8 Other secondary hypertension	0.010	0.990	0.000
I15.2 Hypertension secondary to endocrine disorders	0.010	0.990	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.000	0.990	0.010
V18.4 Driver injured in traffic accident	0.000	0.990	0.010
V18.5 Passenger injured in traffic accident	0.000	0.990	0.010
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.010	0.990	0.000
V18.3 Person injured while boarding or alighting	0.000	0.990	0.009
I51.5 Myocardial degeneration	0.009	0.990	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.009	0.990	0.000
I47 Paroxysmal tachycardia	0.009	0.991	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.009	0.991	0.000
S72.20 Subtrochanteric fracture (closed)	0.009	0.991	0.000
I42.0 Dilated cardiomyopathy	0.009	0.991	0.000
I42 Cardiomyopathy	0.009	0.991	0.000
I40 Acute myocarditis	0.009	0.991	0.000
I15.9 Seconday hypertension, unspecified	0.009	0.991	0.000
I27.8 Other specified pulmonary heart diseases	0.009	0.991	0.000
S72.3 Fracture of shaft of femur	0.009	0.991	0.000
S70-S79 Injuries to the hip and thigh	0.009	0.991	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.009	0.991	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.008	0.991	0.000
I30.8 Other forms of acute pericarditis	0.008	0.991	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.008	0.991	0.000
S72.7 Multiple fractures of femur	0.008	0.991	0.000
I51.9 Heart disease, unspecified	0.009	0.991	0.000
T51.9 Alcohol, unspecified	0.008	0.992	0.000
I51.0 Cardiac septal defect, acquired	0.008	0.992	0.000
I12 Hypertensive renal disease	0.008	0.992	0.000
T51 Toxic effect of alcohol	0.008	0.992	0.000
I52 Other heart disorders in diseases classified elsewhere	0.008	0.992	0.000
I48 Atrial fibrillation and flutter	0.008	0.992	0.000
I41 Myocarditis in diseases classified elsewhere	0.008	0.992	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I32 Pericarditis in diseases classified elsewhere	0.008	0.992	0.000
I36 Nonrheumatic tricuspid valve disorders	0.008	0.992	0.000
S72.9 Fracture of femur, part unspecified	0.008	0.992	0.000
I42.9 Cardiomyopathy, unspecified	0.008	0.992	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.008	0.992	0.000
S72.31 Fracture of shaft of femur (open)	0.007	0.992	0.000
I27.1 Kyphoscoliotic heart disease	0.007	0.992	0.000
S72.21 Subtrochanteric fracture (open)	0.007	0.992	0.000
S72.8 Fractures of other parts of femur	0.007	0.993	0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.000	0.993	0.007
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.000	0.993	0.007
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.007	0.993	0.000
I40.9 Acute myocarditis, unspecified	0.007	0.993	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.007	0.993	0.000
S71 Open wound of hip and thigh	0.007	0.993	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.007	0.993	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.007	0.993	0.000
I40.0 Infective myocarditis	0.007	0.993	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.007	0.993	0.000
T51.0 Ethanol	0.007	0.993	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.007	0.993	0.000
I31 Other diseases of pericardium	0.007	0.993	0.000
Chapter IX Diseases of the circulatory system	0.007	0.993	0.000
I82.8 Embolism and thrombosis of other specified veins	0.007	0.993	0.000
I37 Pulmonary valve disorders	0.007	0.993	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.007	0.993	0.000
I40.8 Other acute myocarditis	0.007	0.993	0.000
I40.1 Isolated myocarditis	0.007	0.993	0.000
I42.5 Other restrictive cardiomyopathy	0.007	0.993	0.000
I42.4 Endocardial fibroelastosis	0.007	0.993	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.007	0.993	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.007	0.993	0.000
I33 Acute and subacute endocarditis	0.007	0.993	0.000
I82 Other venous embolism and thrombosis	0.007	0.993	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.007	0.993	0.000
T79-T79 Certain early complications of trauma	0.006	0.993	0.000
S78 Traumatic amputation of hip and thigh	0.006	0.993	0.000
S77 Crushing injury of hip and thigh	0.006	0.993	0.000
S75 Injury of blood vessels at hip and thigh level	0.006	0.993	0.000
S74 Injury of nerves at hip and thigh level	0.006	0.993	0.000
T56 Toxic effect of metals	0.006	0.994	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.006	0.994	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.006	0.994	0.000
S72.71 Multiple fractures of femur (open)	0.006	0.994	0.000
S72.70 Multiple fractures of femur (closed)	0.006	0.994	0.000
I42.6 Alcoholic cardiomyopathy	0.006	0.994	0.000
I27.9 Pulmonary heart disease, unspecified	0.006	0.994	0.000
S73.0 Dislocation of hip	0.006	0.994	0.000
D48.1 Connective and other soft tissue	0.006	0.994	0.000
T58 Toxic effect of carbon monoxide	0.006	0.994	0.000
T14.0 Superficial injury of unspecified body region	0.006	0.994	0.000
I42.8 Other cardiomyopathies	0.006	0.994	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.006	0.994	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.006	0.994	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.006	0.994	0.000
T14 Injury of unspecified body region	0.006	0.994	0.000
I15.1 Hypertension secondary to other renal disorders	0.006	0.994	0.000
S71.1 Open wound of thigh	0.006	0.994	0.000
S72.4 Fracture of lower end of femur	0.006	0.994	0.000
I28 Other diseases of pulmonary vessels	0.006	0.994	0.000
V10-V19 Pedal cyclist injured in transport accident	0.000	0.994	0.006
T51.8 Other alcohols	0.006	0.994	0.000
T51.3 Fusel oil	0.006	0.994	0.000
T51.2 2-Propanol	0.006	0.994	0.000
T51.1 Methanol	0.006	0.994	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.006	0.994	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.006	0.994	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.006	0.994	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.006	0.994	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.006	0.994	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.006	0.994	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.006	0.994	0.000
I48.4 Atypical atrial flutter	0.006	0.994	0.000
I48.3 Typical atrial flutter	0.006	0.994	0.000
I48.2 Chronic atrial fibrillation	0.006	0.994	0.000
I48.1 Persistent atrial fibrillation	0.006	0.994	0.000
I48.0 Paroxysmal atrial fibrillation	0.006	0.994	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.006	0.994	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.006	0.994	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.006	0.994	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.006	0.994	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.006	0.994	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.006	0.994	0.000
I46 Cardiac arrest	0.006	0.994	0.000
S72.91 Fracture of femur, part unspecified (open)	0.006	0.994	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.006	0.994	0.000
I82.2 Embolism and thrombosis of vena cava	0.006	0.994	0.000
T56.8 Other metals	0.006	0.994	0.000
I89.1 Lymphangitis	0.006	0.994	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.006	0.994	0.000
I35.1 Aortic (valve) insufficiency	0.006	0.994	0.000
S80.8 Other superficial injuries of lower leg	0.006	0.994	0.000
I31.0 Chronic adhesive pericarditis	0.006	0.994	0.000
I33.9 Acute endocarditis, unspecified	0.006	0.994	0.000
S71.0 Open wound of hip	0.005	0.994	0.000
S72.1 Pertrochanteric fracture	0.005	0.994	0.000
S72.81 Fractures of other parts of femur (open)	0.005	0.994	0.000
S79 Other and unspecified injuries of hip and thigh	0.005	0.994	0.000
I31.1 Chronic constrictive pericarditis	0.005	0.994	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.005	0.994	0.000
T60 Toxic effect of pesticides	0.005	0.994	0.000
T57 Toxic effect of other inorganic substances	0.005	0.994	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.005	0.994	0.000
T52 Toxic effect of organic solvents	0.005	0.994	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.005	0.994	0.000
T55 Toxic effect of soaps and detergents	0.005	0.994	0.000
I82.3 Embolism and thrombosis of renal vein	0.005	0.994	0.000
S73.1 Sprain and strain of hip	0.005	0.994	0.000
I31.9 Disease of pericardium, unspecified	0.005	0.994	0.000
T65 Toxic effect of other and unspecified substances	0.005	0.994	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.005	0.995	0.000
S71.7 Multiple open wounds of of hip and thigh	0.005	0.995	0.000
T62 Toxic effect of other noxious substances eaten as food	0.005	0.995	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.005	0.995	0.000
S76.1 Injury of quadriceps muscle and tendon	0.005	0.995	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.005	0.995	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.005	0.995	0.000
S76.0 Injury of muscle and tendon of hip	0.005	0.995	0.000
I35 Nonrheumatic aortic valve disorders	0.005	0.995	0.000
T54 Toxic effect of corrosive substances	0.005	0.995	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.005	0.995	0.000
S72.30 Fracture of shaft of femur (closed)	0.005	0.995	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.005	0.995	0.000
T79.8 Other early complications of trauma	0.005	0.995	0.000
I31.8 Other specified diseases of pericardium	0.005	0.995	0.000
I31.2 Haemopericardium, not elsewhere classified	0.005	0.995	0.000
I47.0 Reentry ventricular arrhythmia	0.005	0.995	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.000	0.995	0.005
I37.0 Pulmonary valve stenosis	0.005	0.995	0.000
T63 Toxic effect of contact with venomous animals	0.005	0.995	0.000
I37.9 Pulmonary valve disorder, unspecified	0.005	0.995	0.000
I37.8 Other pulmonary valve disorders	0.005	0.995	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.005	0.995	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.005	0.995	0.000
T33-T35 Frostbite	0.005	0.995	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.005	0.995	0.000
T14.1 Open wound of unspecified body region	0.005	0.995	0.000
I28.8 Other specified diseases of pulmonary vessels	0.005	0.995	0.000
I82.1 Thrombophlebitis migrans	0.005	0.995	0.000
I82.0 Budd-Chiari syndrome	0.005	0.995	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.005	0.995	0.000
T79.9 Unspecified early complication of trauma	0.005	0.995	0.000
T79.4 Traumatic shock	0.005	0.995	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.005	0.995	0.000
T79.1 Fat embolism (traumatic)	0.005	0.995	0.000
T79.0 Air embolism (traumatic)	0.005	0.995	0.000
T13 Other injuries of lower limb, level unspecified	0.005	0.995	0.000
I27.2 Other secondary pulmonary hypertension	0.005	0.995	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.005	0.995	0.000
S74.8 Injury of other nerves at hip and thigh level	0.005	0.995	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.005	0.995	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.005	0.995	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.005	0.995	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.005	0.995	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.005	0.995	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.005	0.995	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.005	0.995	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.005	0.995	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.005	0.995	0.000
S75.0 Injury of femoral artery	0.005	0.995	0.000
S77.2 Crushing injury of hip with thigh	0.005	0.995	0.000
S77.1 Crushing injury of thigh	0.005	0.995	0.000
S77.0 Crushing injury of hip	0.005	0.995	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.005	0.995	0.000
S78.1 Traumatic amputation at level between hip and knee	0.005	0.995	0.000
S78.0 Traumatic amputation at hip joint	0.005	0.995	0.000
T56.9 Metal, unspecified	0.005	0.995	0.000
T56.7 Beryllium and its compounds	0.005	0.995	0.000
T56.6 Tin and its compounds	0.005	0.995	0.000
T56.5 Zinc and its compounds	0.005	0.995	0.000
T56.4 Copper and its compounds	0.005	0.995	0.000
T56.3 Cadmium and its compounds	0.005	0.995	0.000
T56.2 Chromium and its compounds	0.005	0.995	0.000
T56.1 Mercury and its compounds	0.005	0.995	0.000
T56.0 Lead and its compounds	0.005	0.995	0.000
I00-I02 Acute rheumatic fever	0.005	0.995	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.005	0.995	0.000
T79.7 Traumatic subcutaneous emphysema	0.005	0.995	0.000
H50.0 Convergent concomitant strabismus	0.000	0.995	0.005
I46.1 Sudden cardiac death, so described	0.005	0.995	0.000
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident	0.000	0.995	0.005
T79.5 Traumatic anuria	0.005	0.995	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.005	0.995	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.005	0.995	0.000
K61.3 Ischiorectal abscess	0.000	0.995	0.005
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.005	0.995	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.005	0.995	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.005	0.995	0.000
T12 Fracture of lower limb, level unspecified	0.005	0.995	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.005	0.995	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.005	0.995	0.000
T10 Fracture of upper limb, level unspecified	0.005	0.995	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.005	0.995	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.005	0.995	0.000
T08 Fracture of spine, level unspecified	0.005	0.995	0.000
I35.8 Other aortic valve disorders	0.005	0.995	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.005	0.995	0.000
T14.2 Fracture of unspecified body region	0.005	0.995	0.000
T14.8 Other injuries of unspecified body region	0.005	0.995	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.005	0.995	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.005	0.995	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.005	0.995	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.005	0.995	0.000
T00-T07 Injuries involving multiple body regions	0.005	0.995	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.005	0.995	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.004	0.995	0.000
I28.1 Aneurysm of pulmonary artery	0.004	0.995	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.004	0.995	0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle	0.000	0.995	0.004
V15 Pedal cyclist injured in collision with railway train or railway vehicle	0.000	0.995	0.004
V13 Pedal cyclist injured in collision with car, pick-up truck or van	0.000	0.995	0.004
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle	0.000	0.995	0.004
V10 Pedal cyclist injured in collision with pedestrian or animal	0.000	0.995	0.004
T15-T19 Effects of foreign body entering through natural orifice	0.005	0.995	0.000
T11 Other injuries of upper limb, level unspecified	0.004	0.995	0.000
S10-S19 Injuries to the neck	0.005	0.995	0.000
I12.9 Hypertensive renal disease without renal failure	0.005	0.995	0.000
S72.80 Fractures of other parts of femur (closed)	0.004	0.995	0.000
S10.9 Superficial injury of neck, part unspecified	0.005	0.995	0.000
I42.2 Other hypertrophic cardiomyopathy	0.004	0.995	0.000
T25 Burn and corrosion of ankle and foot	0.004	0.995	0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.000	0.995	0.004
T21 Burn and corrosion of trunk	0.004	0.995	0.000
V11 Pedal cyclist injured in collision with other pedal cycle	0.000	0.995	0.004
S10 Superficial injury of neck	0.004	0.995	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.004	0.996	0.000
T14.9 Injury, unspecified	0.004	0.996	0.000
V17 Pedal cyclist injured in collision with fixed or stationary object	0.000	0.996	0.004
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.004	0.996	0.000
S72.11 Pertrochanteric fracture (open)	0.004	0.996	0.000
S79.7 Multiple injuries of hip and thigh	0.004	0.996	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.004	0.996	0.000
I45 Other conduction disorders	0.004	0.996	0.000
S72.41 Fracture of lower end of femur (open)	0.004	0.996	0.000
T52.9 Organic solvent, unspecified	0.004	0.996	0.000
T52.8 Other organic solvents	0.004	0.996	0.000
T52.4 Ketones	0.004	0.996	0.000
T52.3 Glycols	0.004	0.996	0.000
T52.2 Homologues of benzene	0.004	0.996	0.000
T52.1 Benzene	0.004	0.996	0.000
T52.0 Petroleum products	0.004	0.996	0.000
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.004	0.996	0.000
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.004	0.996	0.000
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.004	0.996	0.000
T53.5 Chlorofluorocarbons	0.004	0.996	0.000
T53.4 Dichloromethane	0.004	0.996	0.000
T53.3 Tetrachloroethylene	0.004	0.996	0.000
T53.2 Trichloroethylene	0.004	0.996	0.000
T53.1 Chloroform	0.004	0.996	0.000
T53.0 Carbon tetrachloride	0.004	0.996	0.000
T57.9 Inorganic substance, unspecified	0.004	0.996	0.000
T57.8 Other specified inorganic substances	0.004	0.996	0.000
T57.3 Hydrogen cyanide	0.004	0.996	0.000
T57.2 Manganese and its compounds	0.004	0.996	0.000
T57.1 Phosphorus and its compounds	0.004	0.996	0.000
T57.0 Arsenic and its compounds	0.004	0.996	0.000
T60.9 Pesticide, unspecified	0.004	0.996	0.000
T60.8 Other pesticides	0.004	0.996	0.000
T60.4 Rodenticides	0.004	0.996	0.000
T60.3 Herbicides and fungicides	0.004	0.996	0.000
T60.2 Other insecticides	0.004	0.996	0.000
T60.1 Halogenated insecticides	0.004	0.996	0.000
T60.0 Organophosphate and carbamate insecticides	0.004	0.996	0.000
T61.9 Toxic effect of unspecified seafood	0.004	0.996	0.000
T61.8 Toxic effect of other seafoods	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations