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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2240062
log Bayes Factor = 45.5978
Chromosome 6   position 31,114,762  (GRCh37) Explore rs2240062 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.999 0.001 0.000
E03 Other hypothyroidism
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E78.0 Pure hypercholesterolaemia
0.000 0.002 0.998
E10 Insulin-dependent diabetes mellitus
0.000 0.004 0.996
E10.9 Without complications
0.000 0.004 0.996
E11.9 Without complications
0.000 0.004 0.996
E11 Non-insulin-dependent diabetes mellitus
0.000 0.005 0.995
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.008 0.992
L40 Psoriasis
0.000 0.010 0.990
E70-E90 Metabolic disorders
0.000 0.020 0.980
L40.5 Arthropathic psoriasis
0.000 0.034 0.966
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.057 0.943
E05.9 Thyrotoxicosis, unspecified
0.000 0.062 0.938
E14 Unspecified diabetes mellitus
0.000 0.069 0.931
L40.8 Other psoriasis
0.000 0.120 0.880
E78.8 Other disorders of lipoprotein metabolism
0.000 0.134 0.866
G35-G37 Demyelinating diseases of the central nervous system
0.854 0.146 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.154 0.846
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.159 0.841
E14.3 With ophthalmic complications
0.000 0.166 0.834
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.175 0.825
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.182 0.818
G37 Other demyelinating diseases of central nervous system
0.816 0.184 0.000
L40.0 Psoriasis vulgaris
0.000 0.193 0.807
E11.0 With coma
0.000 0.198 0.802
E78.2 Mixed hyperlipidaemia
0.000 0.198 0.802
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.200 0.800
E14.9 Without complications
0.000 0.206 0.794
E10.3 With ophthalmic complications
0.000 0.210 0.790
E10.8 With unspecified complications
0.000 0.214 0.785
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.219 0.781
G37.9 Demyelinating disease of central nervous system, unspecified
0.774 0.226 0.000
E78.4 Other hyperlipidaemia
0.000 0.233 0.767
E13 Other specified diabetes mellitus
0.000 0.234 0.766
E11.2 With renal complications
0.000 0.237 0.763
E78.1 Pure hyperglyceridaemia
0.000 0.240 0.760
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.242 0.758
L40.1 Generalised pustular psoriasis
0.000 0.248 0.752
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.251 0.749
E10.6 With other specified complications
0.000 0.255 0.745
E78.5 Hyperlipidaemia, unspecified
0.000 0.261 0.739
L40-L45 Papulosquamous disorders
0.000 0.263 0.737
E11.1 With ketoacidosis
0.000 0.264 0.736
E78.6 Lipoprotein deficiency
0.000 0.274 0.726
E74 Other disorders of carbohydrate metabolism
0.000 0.280 0.720
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.8 Other specified hypothyroidism
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E10.7 With multiple complications
0.000 0.286 0.714
E07 Other disorders of thyroid
0.000 0.286 0.714
E11.7 With multiple complications
0.000 0.287 0.713
E14.1 With ketoacidosis
0.000 0.287 0.713
E78.3 Hyperchylomicronaemia
0.000 0.289 0.711
L40.4 Guttate psoriasis
0.000 0.290 0.710
L40.2 Acrodermatitis continua
0.000 0.290 0.710
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.293 0.707
E14.5 With peripheral circulatory complications
0.000 0.295 0.705
E79 Disorders of purine and pyrimidine metabolism
0.000 0.297 0.702
E77 Disorders of glycoprotein metabolism
0.000 0.297 0.702
E76 Disorders of glycosaminoglycan metabolism
0.000 0.297 0.702
E72 Other disorders of amino-acid metabolism
0.000 0.297 0.702
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.297 0.702
E70 Disorders of aromatic amino-acid metabolism
0.000 0.297 0.702
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.297 0.702
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.313 0.687
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.313 0.686
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.316 0.684
E05.5 Thyroid crisis or storm
0.000 0.324 0.676
E05.4 Thyrotoxicosis factitia
0.000 0.324 0.676
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.324 0.676
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.324 0.676
G37.8 Other specified demyelinating diseases of central nervous system
0.676 0.324 0.000
E84 Cystic fibrosis
0.000 0.324 0.675
E14.4 With neurological complications
0.000 0.325 0.675
L43 Lichen planus
0.000 0.327 0.673
E14.7 With multiple complications
0.000 0.332 0.667
E14.0 With coma
0.000 0.332 0.667
E10.0 With coma
0.000 0.333 0.667
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.334 0.666
K51.9 Ulcerative colitis, unspecified
0.658 0.342 0.000
G36 Other acute disseminated demyelination
0.656 0.344 0.000
K51 Ulcerative colitis
0.654 0.346 0.000
E14.2 Withrenal complications
0.000 0.351 0.649
L43.9 Lichen planus, unspecified
0.000 0.356 0.644
E14.6 With other specified complications
0.000 0.361 0.639
E03.1 Congenital hypothyroidism without goitre
0.000 0.362 0.638
K51.2 Ulcerative (chronic) proctitis
0.634 0.366 0.000
E40-E46 Malnutrition
0.000 0.369 0.631
E13.9 Without complications
0.000 0.372 0.628
E10.5 With peripheral circulatory complications
0.000 0.384 0.616
E14.8 With unspecified complications
0.000 0.386 0.614
E10.1 With ketoacidosis
0.000 0.395 0.605
E11.8 With unspecified complications
0.000 0.398 0.602
E10.2 With renal complications
0.000 0.398 0.601
K51.5 Mucosal proctocolitis
0.599 0.401 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.591 0.409 0.000
E85 Amyloidosis
0.000 0.413 0.587
G37.5 Concentric sclerosis [Balo]
0.585 0.415 0.000
G37.4 Subacute necrotising myelitis
0.585 0.415 0.000
G37.2 Central pontine myelinolysis
0.585 0.415 0.000
G37.1 Central demyelination of corpus callosum
0.585 0.415 0.000
G37.0 Diffuse sclerosis
0.585 0.415 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.415 0.585
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.419 0.581
E80.2 Other porphyria
0.000 0.425 0.575
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.425 0.575
E16 Other disorders of pancreatic internal secretion
0.000 0.429 0.571
E80.6 Other disorders of bilirubin metabolism
0.000 0.432 0.568
L42 Pityriasis rosea
0.000 0.433 0.567
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.565 0.435 0.000
E73 Lactose intolerance
0.000 0.441 0.558
E80.4 Gilbert's syndrome
0.000 0.449 0.551
E13.8 With unspecified complications
0.000 0.451 0.549
E13.7 With multiple complications
0.000 0.451 0.549
E13.6 With other specified complications
0.000 0.451 0.549
E13.5 With peripheral circulatory complications
0.000 0.451 0.549
E13.4 With neurological complications
0.000 0.451 0.549
E13.2 With renal complications
0.000 0.451 0.549
E13.1 With ketoacidosis
0.000 0.451 0.549
E13.0 With coma
0.000 0.451 0.549
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.456 0.544
E80.5 Crigler-Najjar syndrome
0.000 0.456 0.544
E80.3 Defects of catalase and peroxydase
0.000 0.456 0.544
E80.0 Hereditary erythropoietic porphyria
0.000 0.456 0.544
E80.1 Porphyria cutanea tarda
0.000 0.458 0.541
E07.9 Disorder of thyroid, unspecified
0.000 0.459 0.541
K51.4 Pseudopolyposis of colon
0.538 0.462 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.463 0.537
E83 Disorders of mineral metabolism
0.458 0.463 0.079
E05.8 Other thyrotoxicosis
0.000 0.465 0.534
L44 Other papulosquamous disorders
0.000 0.472 0.528
L41 Parapsoriasis
0.000 0.472 0.528
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.472 0.528
K51.1 Ulcerative (chronic) ileocolitis
0.527 0.473 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.484 0.516
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.484 0.516
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.484 0.516
E74.2 Disorders of galactose metabolism
0.000 0.484 0.516
E74.1 Disorders of fructose metabolism
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
G36.0 Neuromyelitis optica [Devic]
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E07.1 Dyshormogenetic goitre
0.000 0.488 0.512
E07.0 Hypersecretion of calcitonin
0.000 0.488 0.512
E13.3 With ophthalmic complications
0.000 0.496 0.504
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.496 0.504
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.496 0.504
E70.3 Albinism
0.000 0.496 0.504
E70.2 Disorders of tyrosine metabolism
0.000 0.496 0.504
E70.1 Other hyperphenylalaninaemias
0.000 0.496 0.504
E70.0 Classical phenylketonuria
0.000 0.496 0.504
E71.3 Disorders of fatty-acid metabolism
0.000 0.496 0.504
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.496 0.504
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.496 0.504
E71.0 Maple-syrup-urine disease
0.000 0.496 0.504
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.496 0.504
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.496 0.504
E72.5 Disorders of glycine metabolism
0.000 0.496 0.504
E72.4 Disorders of ornithine metabolism
0.000 0.496 0.504
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.496 0.504
E72.2 Disorders of urea cycle metabolism
0.000 0.496 0.504
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.496 0.504
E72.0 Disorders of amino-acid transport
0.000 0.496 0.504
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.496 0.504
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.496 0.504
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.496 0.504
E76.2 Other mucopolysaccharidoses
0.000 0.496 0.504
E76.1 Mucopolysaccharidosis, type II
0.000 0.496 0.504
E76.0 Mucopolysaccharidosis, type I
0.000 0.496 0.504
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.496 0.504
E77.8 Other disorders of glycoprotein metabolism
0.000 0.496 0.504
E77.1 Defects in glycoprotein degradation
0.000 0.496 0.504
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.496 0.504
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.496 0.504
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.496 0.504
E79.1 Lesch-Nyhan syndrome
0.000 0.496 0.504
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.496 0.504
E75.6 Lipid storage disorder, unspecified
0.000 0.508 0.492
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.508 0.492
E75.3 Sphingolipidosis, unspecified
0.000 0.508 0.492
E75.2 Other sphingolipidosis
0.000 0.508 0.492
E75.1 Other gangliosidosis
0.000 0.508 0.492
E75.0 GM2 gangliosidosis
0.000 0.508 0.492
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.510 0.490
E10.4 With neurological complications
0.000 0.510 0.489
E88 Other metabolic disorders
0.000 0.511 0.489
E84.8 Cystic fibrosis with other manifestations
0.000 0.515 0.484
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.515 0.484
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.515 0.484
K51.8 Other ulcerative colitis
0.483 0.517 0.000
L43.3 Subacute (active) lichen planus
0.000 0.517 0.483
L43.2 Lichenoid drug reaction
0.000 0.517 0.483
L43.1 Bullous lichen planus
0.000 0.517 0.483
L43.0 Hypertrophic lichen planus
0.000 0.517 0.483
E11.5 With peripheral circulatory complications
0.000 0.519 0.481
E07.8 Other specified disorders of thyroid
0.000 0.523 0.477
E75.5 Other lipid storage disorders
0.000 0.524 0.476
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.527 0.473
G36.9 Acute disseminated demyelination, unspecified
0.470 0.530 0.000
G36.8 Other specified acute disseminated demyelination
0.470 0.530 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.470 0.530 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.542 0.457
E16.1 Other hypoglycaemia
0.000 0.543 0.457
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.547 0.453
E45 Retarded development following protein-energy malnutrition
0.000 0.547 0.453
E43 Unspecified severe protein-energy malnutrition
0.000 0.547 0.453
E42 Marasmic kwashiorkor
0.000 0.547 0.453
E41 Nutritional marasmus
0.000 0.547 0.453
E40 Kwashiorkor
0.000 0.547 0.453
E11.6 With other specified complications
0.000 0.548 0.452
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.551 0.449
E74.0 Glycogen storage disease
0.000 0.554 0.446
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.557 0.443
E85.8 Other amyloidosis
0.000 0.579 0.421
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.579 0.421
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.579 0.421
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.579 0.421
M06 Other rheumatoid arthritis
0.000 0.586 0.414
K90 Intestinal malabsorption
0.001 0.587 0.412
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.591 0.409
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.591 0.409
E16.4 Abnormal secretion of gastrin
0.000 0.591 0.409
E16.3 Increased secretion of glucagon
0.000 0.591 0.409
E73.8 Other lactose intolerance
0.000 0.599 0.400
E73.1 Secondary lactase deficiency
0.000 0.599 0.400
E73.0 Congenital lactase deficiency
0.000 0.599 0.400
E85.9 Amyloidosis, unspecified
0.000 0.601 0.399
K51.0 Ulcerative (chronic) enterocolitis
0.394 0.606 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.608 0.392
E85.4 Organ-limited amyloidosis
0.000 0.610 0.390
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.611 0.388
L43.8 Other lichen planus
0.000 0.614 0.386
E83.9 Disorder of mineral metabolism, unspecified
0.328 0.615 0.057
E83.8 Other disorders of mineral metabolism
0.328 0.615 0.057
E83.2 Disorders of zinc metabolism
0.328 0.615 0.057
E83.0 Disorders of copper metabolism
0.328 0.615 0.057
E83.3 Disorders of phosphorus metabolism
0.350 0.619 0.032
L41.9 Parapsoriasis, unspecified
0.000 0.621 0.379
L41.8 Other parapsoriasis
0.000 0.621 0.379
L41.5 Retiform parapsoriasis
0.000 0.621 0.379
L41.4 Large plaque parapsoriasis
0.000 0.621 0.379
L41.3 Small plaque parapsoriasis
0.000 0.621 0.379
L41.2 Lymphomatoid papulosis
0.000 0.621 0.379
L41.1 Pityriasis lichenoides chronica
0.000 0.621 0.379
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.621 0.379
L44.9 Papulosquamous disorder, unspecified
0.000 0.621 0.379
L44.8 Other specified papulosquamous disorders
0.000 0.621 0.379
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.621 0.379
L44.3 Lichen ruber moniliformis
0.000 0.621 0.379
L44.2 Lichen striatus
0.000 0.621 0.379
L44.1 Lichen nitidus
0.000 0.621 0.379
L44.0 Pityriasis rubra pilaris
0.000 0.621 0.379
E85.3 Secondary systemic amyloidosis
0.000 0.622 0.377
E11.4 With neurological complications
0.000 0.622 0.377
E65-E68 Obesity and other hyperalimentation
0.000 0.624 0.376
E89.3 Postprocedural hypopituitarism
0.000 0.628 0.372
E46 Unspecified protein-energy malnutrition
0.000 0.632 0.368
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.637 0.363
E06 Thyroiditis
0.001 0.638 0.362
E89.4 Postprocedural ovarian failure
0.000 0.643 0.357
E88.2 Lipomatosis, not elsewhere classified
0.000 0.645 0.355
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.648 0.352
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.648 0.352
E89.5 Postprocedural testicular hypofunction
0.000 0.648 0.352
E89.1 Postprocedural hypoinsulinaemia
0.000 0.648 0.352
E88.9 Metabolic disorder, unspecified
0.000 0.649 0.350
E88.8 Other specified metabolic disorders
0.000 0.649 0.350
E88.3 Tumour lysis syndrome
0.000 0.649 0.350
E50-E64 Other nutritional deficiencies
0.001 0.655 0.344
M06.3 Rheumatoid nodule
0.000 0.661 0.339
I25 Chronic ischaemic heart disease
0.000 0.661 0.339
M06.4 Inflammatory polyarthropathy
0.000 0.667 0.333
I25.5 Ischaemic cardiomyopathy
0.000 0.667 0.333
E16.2 Hypoglycaemia, unspecified
0.000 0.669 0.331
E44.1 Mild protein-energy malnutrition
0.000 0.675 0.325
E44.0 Moderate protein-energy malnutrition
0.000 0.675 0.325
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.677 0.322
I20-I25 Ischaemic heart diseases
0.000 0.682 0.318
I25.1 Atherosclerotic heart disease
0.000 0.682 0.318
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.683 0.317
I22 Subsequent myocardial infarction
0.000 0.687 0.313
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.691 0.309
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.699 0.301
M06.2 Rheumatoid bursitis
0.000 0.703 0.297
M06.1 Adult-onset Still's disease
0.000 0.703 0.297
K90.3 Pancreatic steatorrhoea
0.001 0.704 0.295
K90.2 Blind loop syndrome, not elsewhere classified
0.001 0.704 0.295
K90.1 Tropical sprue
0.001 0.704 0.295
E83.4 Disorders of magnesium metabolism
0.258 0.712 0.029
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.712 0.287
M06.8 Other specified rheumatoid arthritis
0.000 0.715 0.285
E89.2 Postprocedural hypoparathyroidism
0.000 0.719 0.281
I25.2 Old myocardial infarction
0.000 0.720 0.280
E20-E35 Disorders of other endocrine glands
0.000 0.720 0.280
I24 Other acute ischaemic heart diseases
0.000 0.722 0.278
K90.9 Intestinal malabsorption, unspecified
0.000 0.724 0.276
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.725 0.275
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.729 0.271
E67 Other hyperalimentation
0.000 0.730 0.270
E68 Sequelae of hyperalimentation
0.000 0.730 0.270
I23 Certain current complications following acute myocardial infarction
0.000 0.730 0.270
K90.8 Other intestinal malabsorption
0.001 0.731 0.268
M06.34 Rheumatoid nodule (Hand)
0.000 0.732 0.268
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.736 0.264
E06.5 Other chronic thyroiditis
0.001 0.740 0.259
E06.4 Drug-induced thyroiditis
0.001 0.740 0.259
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.001 0.740 0.259
E06.0 Acute thyroiditis
0.001 0.740 0.259
E73.9 Lactose intolerance, unspecified
0.001 0.743 0.256
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.745 0.255
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.753 0.246
E63 Other nutritional deficiencies
0.001 0.753 0.246
E56 Other vitamin deficiencies
0.001 0.753 0.246
E50 Vitamin A deficiency
0.001 0.753 0.246
E60 Dietary zinc deficiency
0.001 0.753 0.246
E59 Dietary selenium deficiency
0.001 0.753 0.246
E58 Dietary calcium deficiency
0.001 0.753 0.246
E54 Ascorbic acid deficiency
0.001 0.753 0.246
E52 Niacin deficiency [pellagra]
0.001 0.753 0.246
E51 Thiamine deficiency
0.001 0.755 0.244
I22.8 Subsequent myocardial infarction of other sites
0.000 0.756 0.243
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.757 0.243
M06.38 Rheumatoid nodule (Other)
0.000 0.757 0.243
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.757 0.243
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.757 0.243
M06.33 Rheumatoid nodule (Forearm)
0.000 0.757 0.243
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.757 0.243
I25.6 Silent myocardial ischaemia
0.000 0.757 0.243
E28 Ovarian dysfunction
0.000 0.759 0.241
E06.1 Subacute thyroiditis
0.001 0.760 0.239
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.760 0.240
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.761 0.239
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.761 0.239
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.761 0.239
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.761 0.239
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.761 0.239
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.761 0.239
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.761 0.239
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.761 0.239
E61 Deficiency of other nutrient elements
0.001 0.761 0.238
I21 Acute myocardial infarction
0.000 0.763 0.237
I23.8 Other current complications following acute myocardial infarction
0.000 0.765 0.235
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.769 0.231
M06.0 Seronegative rheumatoid arthritis
0.000 0.771 0.228
E24 Cushing's syndrome
0.000 0.773 0.227
E65 Localised adiposity
0.000 0.774 0.225
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.775 0.225
E28.2 Polycystic ovarian syndrome
0.000 0.776 0.224
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.777 0.223
I25.3 Aneurysm of heart
0.000 0.778 0.222
I25.4 Coronary artery aneurysm
0.000 0.780 0.220
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.781 0.219
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.781 0.219
E83.5 Disorders of calcium metabolism
0.206 0.784 0.010
E23 Hypofunction and other disorders of pituitary gland
0.000 0.785 0.215
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.787 0.213
M06.18 Adult-onset Still's disease (Other)
0.000 0.787 0.213
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.787 0.213
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.787 0.213
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.787 0.213
M06.14 Adult-onset Still's disease (Hand)
0.000 0.787 0.213
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.787 0.213
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.787 0.213
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.787 0.213
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.787 0.213
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.787 0.213
M06.28 Rheumatoid bursitis (Other)
0.000 0.787 0.213
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.787 0.213
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.787 0.213
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.787 0.213
M06.24 Rheumatoid bursitis (Hand)
0.000 0.787 0.213
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.787 0.213
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.787 0.213
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.787 0.213
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.787 0.213
E26 Hyperaldosteronism
0.000 0.792 0.208
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.795 0.204
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.795 0.204
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.795 0.204
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.795 0.204
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.795 0.204
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.795 0.204
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.795 0.204
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.795 0.204
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.795 0.204
E11.3 With ophthalmic complications
0.000 0.797 0.203
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.799 0.201
E32 Diseases of thymus
0.000 0.799 0.201
E31 Polyglandular dysfunction
0.000 0.799 0.201
E30 Disorders of puberty, not elsewhere classified
0.000 0.799 0.201
E25 Adrenogenital disorders
0.000 0.799 0.201
I21.9 Acute myocardial infarction, unspecified
0.000 0.802 0.198
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.804 0.196
E67.8 Other specified hyperalimentation
0.000 0.806 0.193
E67.3 Hypervitaminosis D
0.000 0.806 0.193
E67.2 Megavitamin-B6 syndrome
0.000 0.806 0.193
E67.1 Hypercarotenaemia
0.000 0.806 0.193
E67.0 Hypervitaminosis A
0.000 0.806 0.193
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.806 0.194
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.806 0.194
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.806 0.194
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.806 0.194
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.806 0.194
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.806 0.194
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.806 0.194
I21.4 Acute subendocardial myocardial infarction
0.000 0.808 0.192
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.808 0.192
E24.2 Drug-induced Cushing's syndrome
0.000 0.816 0.184
E50.9 Vitamin A deficiency, unspecified
0.001 0.823 0.177
E50.8 Other manifestations of vitamin A deficiency
0.001 0.823 0.177
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.823 0.177
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.823 0.177
E50.5 Vitamin A deficiency with night blindness
0.001 0.823 0.177
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.823 0.177
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.823 0.177
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.823 0.177
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.823 0.177
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.823 0.177
E56.9 Vitamin deficiency, unspecified
0.001 0.823 0.177
E56.8 Deficiency of other vitamins
0.001 0.823 0.177
E56.1 Deficiency of vitamin K
0.001 0.823 0.177
E56.0 Deficiency of vitamin E
0.001 0.823 0.177
E63.9 Nutritional deficiency, unspecified
0.001 0.823 0.177
E63.8 Other specified nutritional deficiencies
0.001 0.823 0.177
E63.1 Imbalance of constituents of food intake
0.001 0.823 0.177
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.823 0.177
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.823 0.177
E64.8 Sequelae of other nutritional deficiencies
0.001 0.823 0.177
E64.3 Sequelae of rickets
0.001 0.823 0.177
E64.2 Sequelae of vitamin C deficiency
0.001 0.823 0.177
E64.1 Sequelae of vitamin A deficiency
0.001 0.823 0.177
E64.0 Sequelae of protein-energy malnutrition
0.001 0.823 0.177
E23.7 Disorder of pituitary gland, unspecified
0.000 0.823 0.177
E61.1 Iron deficiency
0.000 0.823 0.176
E06.9 Thyroiditis, unspecified
0.001 0.824 0.175
E51.9 Thiamine deficiency, unspecified
0.001 0.824 0.175
E51.8 Other manifestations of thiamine deficiency
0.001 0.824 0.175
E51.1 Beriberi
0.001 0.824 0.175
E28.9 Ovarian dysfunction, unspecified
0.000 0.827 0.173
E28.8 Other ovarian dysfunction
0.000 0.827 0.173
E28.1 Androgen excess
0.000 0.827 0.173
E28.0 Oestrogen excess
0.000 0.827 0.173
E51.2 Wernicke's encephalopathy
0.001 0.827 0.172
E61.9 Deficiency of nutrient element, unspecified
0.001 0.828 0.171
E61.8 Deficiency of other specified nutrient elements
0.001 0.828 0.171
E61.7 Deficiency of multiple nutrient elements
0.001 0.828 0.171
E61.6 Vanadium deficiency
0.001 0.828 0.171
E61.5 Molybdenum deficiency
0.001 0.828 0.171
E61.4 Chromium deficiency
0.001 0.828 0.171
E61.3 Manganese deficiency
0.001 0.828 0.171
E61.0 Copper deficiency
0.001 0.828 0.171
E55 Vitamin D deficiency
0.001 0.829 0.170
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.830 0.170
E24.9 Cushing's syndrome, unspecified
0.000 0.830 0.170
E29 Testicular dysfunction
0.000 0.831 0.169
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.834 0.166
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.836 0.164
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.836 0.164
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.836 0.164
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.836 0.164
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.836 0.164
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.836 0.164
E20 Hypoparathyroidism
0.000 0.836 0.163
E24.8 Other Cushing's syndrome
0.000 0.837 0.163
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.837 0.163
E24.3 Ectopic ACTH syndrome
0.000 0.837 0.163
E24.1 Nelson's syndrome
0.000 0.837 0.163
E24.0 Pituitary-dependent Cushing's disease
0.000 0.837 0.163
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.838 0.162
I24.1 Dressler's syndrome
0.000 0.840 0.160
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.840 0.160

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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