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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2240066
log Bayes Factor = 13.7416
Chromosome 6   position 31,114,335  (GRCh37) Explore rs2240066 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
M45 Ankylosing spondylitis
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.997 0.003 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.988 0.012 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.988 0.012 0.000
# Top node
0.982 0.018 0.000
M06.0 Seronegative rheumatoid arthritis
0.959 0.041 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.041 0.959
M48 Other spondylopathies
0.957 0.043 0.000
Chapter X Diseases of the respiratory system
0.949 0.051 0.000
M07 Psoriatic and enteropathic arthropathies
0.939 0.061 0.000
M48.0 Spinal stenosis
0.928 0.072 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.925 0.075 0.000
Chapter I Certain infectious and parasitic diseases
0.921 0.079 0.000
M48.02 Spinal stenosis (Cervical region)
0.920 0.080 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.918 0.082 0.000
Chapter V Mental and behavioural disorders
0.904 0.096 0.000
M07.3 Other psoriatic arthropathies
0.895 0.105 0.000
Chapter VI Diseases of the nervous system
0.892 0.108 0.000
O60-O75 Complications of labour and delivery
0.884 0.116 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.882 0.118 0.000
M46 Other inflammatory spondylopathies
0.875 0.125 0.000
Chapter VII Diseases of the eye and adnexa
0.867 0.133 0.000
J30-J39 Other diseases of upper respiratory tract
0.864 0.136 0.000
J20-J22 Other acute lower respiratory infections
0.858 0.142 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.855 0.145 0.000
J32 Chronic sinusitis
0.852 0.148 0.000
H20 Iridocyclitis
0.851 0.149 0.000
J32.9 Chronic sinusitis, unspecified
0.848 0.152 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.848 0.152 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.846 0.154 0.000
H20.9 Iridocyclitis, unspecified
0.845 0.155 0.000
G90-G99 Other disorders of the nervous system
0.844 0.156 0.000
J00-J06 Acute upper respiratory infections
0.844 0.156 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.831 0.169 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.826 0.174 0.000
Chapter XX External causes of morbidity and mortality
0.826 0.174 0.000
G91 Hydrocephalus
0.819 0.181 0.000
Chapter II Neoplasms
0.817 0.183 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.817 0.183 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.815 0.185 0.000
M06.4 Inflammatory polyarthropathy
0.813 0.187 0.000
Chapter VIII Diseases of the ear and mastoid process
0.810 0.190 0.000
Chapter XXII Codes for special purposes
0.809 0.191 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.807 0.193 0.000
M10 Gout
0.805 0.195 0.000
D10-D36 Benign neoplasms
0.802 0.198 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.800 0.200 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.799 0.201 0.000
D12.5 Sigmoid colon
0.794 0.206 0.000
B25-B34 Other viral diseases
0.791 0.209 0.000
J09-J18 Influenza and pneumonia
0.786 0.214 0.000
F30-F39 Mood [affective] disorders
0.786 0.214 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.786 0.214 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.780 0.220 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.779 0.221 0.000
G91.9 Hydrocephalus, unspecified
0.777 0.223 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.777 0.223 0.000
J38.3 Other diseases of vocal cords
0.777 0.223 0.000
J22 Unspecified acute lower respiratory infection
0.776 0.224 0.000
M86-M90 Other osteopathies
0.773 0.227 0.000
J02 Acute pharyngitis
0.772 0.228 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.770 0.230 0.000
M00-M03 Infectious arthropathies
0.769 0.231 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.767 0.233 0.000
O00-O08 Pregnancy with abortive outcome
0.759 0.241 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.758 0.242 0.000
G20-G26 Extrapyramidal and movement disorders
0.757 0.243 0.000
D17 Benign lipomatous neoplasm
0.756 0.244 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.754 0.246 0.000
A30-A49 Other bacterial diseases
0.751 0.249 0.000
M06.3 Rheumatoid nodule
0.751 0.249 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.748 0.252 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.747 0.253 0.000
M40-M43 Deforming dorsopathies
0.747 0.253 0.000
O85-O92 Complications predominantly related to the puerperium
0.747 0.253 0.000
F80-F89 Disorders of psychological development
0.746 0.254 0.000
C64-C68 Malignant neoplasms of urinary tract
0.745 0.255 0.000
J40-J47 Chronic lower respiratory diseases
0.744 0.256 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.743 0.257 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.743 0.257 0.000
H40-H42 Glaucoma
0.742 0.258 0.000
Y45.0 Opioids and related analgesics
0.742 0.258 0.000
G30-G32 Other degenerative diseases of the nervous system
0.741 0.259 0.000
H55-H59 Other disorders of eye and adnexa
0.741 0.259 0.000
F60-F69 Disorders of adult personality and behaviour
0.738 0.262 0.000
H65-H75 Diseases of middle ear and mastoid
0.738 0.262 0.000
O75.0 Maternal distress during labour and delivery
0.737 0.263 0.000
M11 Other crystal arthropathies
0.737 0.263 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.737 0.263 0.000
O70 Perineal laceration during delivery
0.736 0.264 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.733 0.267 0.000
F31 Bipolar affective disorder
0.731 0.268 0.000
J38.1 Polyp of vocal cord and larynx
0.728 0.272 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.728 0.272 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.727 0.273 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.726 0.274 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.722 0.278 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.720 0.280 0.000
J02.9 Acute pharyngitis, unspecified
0.720 0.280 0.000
M60-M63 Disorders of muscles
0.720 0.280 0.000
J38.7 Other diseases of larynx
0.719 0.281 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.717 0.283 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.717 0.283 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.717 0.283 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.717 0.283 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.717 0.283 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.717 0.283 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.717 0.283 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
M49 Spondylopathies in diseases classified elsewhere
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
G91.1 Obstructive hydrocephalus
0.716 0.284 0.000
Y52 Agents primarily affecting the cardiovascular system
0.714 0.286 0.000
B35-B49 Mycoses
0.710 0.289 0.000
A46 Erysipelas
0.708 0.292 0.000
O72 Postpartum haemorrhage
0.707 0.293 0.000
M91-M94 Chondropathies
0.704 0.296 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.704 0.296 0.000
X60-X84 Intentional self-harm
0.704 0.296 0.000
J01 Acute sinusitis
0.702 0.298 0.000
B15-B19 Viral hepatitis
0.701 0.298 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.701 0.299 0.000
J43 Emphysema
0.700 0.300 0.000
C67 Malignant neoplasm of bladder
0.699 0.301 0.000
B99-B99 Other infectious diseases
0.698 0.302 0.000
B34 Viral infection of unspecified site
0.697 0.302 0.000
F99-F99 Unspecified mental disorder
0.689 0.311 0.000
D12.4 Descending colon
0.689 0.311 0.000
A00-A09 Intestinal infectious diseases
0.688 0.312 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.688 0.312 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.688 0.312 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.688 0.312 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.688 0.312 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.688 0.312 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.688 0.312 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.688 0.312 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.688 0.312 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.688 0.312 0.000
M48.9 Spondylopathy, unspecified
0.686 0.314 0.000
M48.8 Other specified spondylopathies
0.686 0.314 0.000
M48.4 Fatigue fracture of vertebra
0.686 0.314 0.000
M48.3 Traumatic spondylopathy
0.686 0.314 0.000
M48.2 Kissing spine
0.686 0.314 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.686 0.314 0.000
O62 Abnormalities of forces of labour
0.685 0.315 0.000
D12.3 Transverse colon
0.685 0.315 0.000
C81 Hodgkin's disease
0.684 0.316 0.000
Y57 Other and unspecified drugs and medicaments
0.683 0.317 0.000
M05 Seropositive rheumatoid arthritis
0.683 0.317 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.683 0.317 0.000
H20.0 Acute and subacute iridocyclitis
0.682 0.318 0.000
Q60-Q64 Congenital malformations of the urinary system
0.681 0.319 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.680 0.320 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.679 0.321 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.678 0.321 0.000
J60-J70 Lung diseases due to external agents
0.678 0.321 0.000
F10.2 Dependence syndrome
0.678 0.322 0.000
H20.1 Chronic iridocyclitis
0.678 0.322 0.000
J47 Bronchiectasis
0.676 0.324 0.000
G24 Dystonia
0.676 0.324 0.000
G70-G73 Diseases of myoneural junction and muscle
0.674 0.326 0.000
M07.6 Other enteropathic arthropathies
0.673 0.327 0.000
M07.5 Arthropathy in ulcerative colitis
0.673 0.327 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.673 0.327 0.000
M07.2 Psoriatic spondylitis
0.673 0.327 0.000
M07.1 Arthritis mutilans
0.673 0.327 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.673 0.327 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.672 0.328 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.672 0.328 0.000
Q80-Q89 Other congenital malformations
0.671 0.329 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.671 0.329 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.669 0.331 0.000
O70.1 Second degree perineal laceration during delivery
0.669 0.331 0.000
J43.9 Emphysema, unspecified
0.669 0.331 0.000
J38.6 Stenosis of larynx
0.667 0.333 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.667 0.333 0.000
H53-H54 Visual disturbances and blindness
0.667 0.333 0.000
O73 Retained placenta and membranes, without haemorrhage
0.666 0.334 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.666 0.334 0.000
M10.9 Gout, unspecified
0.666 0.334 0.000
J20 Acute bronchitis
0.665 0.335 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.665 0.335 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.665 0.335 0.000
M48.04 Spinal stenosis (Thoracic region)
0.665 0.335 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.665 0.335 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.665 0.335 0.000
G90 Disorders of autonomic nervous system
0.664 0.336 0.000
M48.09 Spinal stenosis (Site unspecified)
0.662 0.337 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.662 0.338 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.662 0.338 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.661 0.339 0.000
D34 Benign neoplasm of thyroid gland
0.661 0.339 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.660 0.339 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.660 0.339 0.000
B50-B64 Protozoal diseases
0.660 0.339 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.660 0.339 0.000
A75-A79 Rickettsioses
0.660 0.339 0.000
A70-A74 Other diseases caused by chlamydiae
0.660 0.339 0.000
A65-A69 Other spirochaetal diseases
0.660 0.339 0.000
A20-A28 Certain zoonotic bacterial diseases
0.660 0.339 0.000
A15-A19 Tuberculosis
0.660 0.339 0.000
F31.9 Bipolar affective disorder, unspecified
0.659 0.341 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.658 0.342 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.657 0.343 0.000
J32.0 Chronic maxillary sinusitis
0.656 0.344 0.000
B95-B98 Bacterial, viral and other infectious agents
0.655 0.345 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.654 0.346 0.000
H40 Glaucoma
0.653 0.347 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.653 0.347 0.000
G60 Hereditary and idiopathic neuropathy
0.653 0.347 0.000
J95-J99 Other diseases of the respiratory system
0.652 0.348 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.652 0.348 0.000
J38.2 Nodules of vocal cords
0.650 0.350 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.650 0.350 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.649 0.351 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.648 0.352 0.000
J39 Other diseases of upper respiratory tract
0.648 0.352 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.648 0.352 0.000
F70-F79 Mental retardation
0.648 0.352 0.000
F33 Recurrent depressive disorder
0.647 0.353 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.647 0.353 0.000
F81 Specific developmental disorders of scholastic skills
0.646 0.354 0.000
C83.3 Large cell (diffuse)
0.646 0.354 0.000
C67.9 Bladder, unspecified
0.645 0.355 0.000
J11 Influenza, virus not identified
0.645 0.355 0.000
H57 Other disorders of eye and adnexa
0.644 0.356 0.000
M07.38 Other psoriatic arthropathies (Other)
0.642 0.358 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.642 0.358 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.642 0.358 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.642 0.358 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.642 0.358 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.642 0.358 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.642 0.358 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.642 0.358 0.000
H25-H28 Disorders of lens
0.642 0.358 0.000
B65-B83 Helminthiases
0.640 0.360 0.000
Y00-Y09 Assault
0.639 0.361 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.638 0.362 0.000
M65-M68 Disorders of synovium and tendon
0.638 0.362 0.000
L20-L30 Dermatitis and eczema
0.636 0.363 0.000
V40-V49 Car occupant injured in transport accident
0.636 0.364 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.636 0.364 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.635 0.365 0.000
O74 Complications of anaesthesia during labour and delivery
0.634 0.366 0.000
O71 Other obstetric trauma
0.634 0.366 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.634 0.366 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.634 0.366 0.000
O60 Preterm delivery
0.634 0.366 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.634 0.366 0.000
G93 Other disorders of brain
0.634 0.366 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.634 0.366 0.000
O75.8 Other specified complications of labour and delivery
0.632 0.368 0.000
F11 Mental and behavioural disorders due to use of opioids
0.631 0.369 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.631 0.369 0.000
B34.9 Viral infection, unspecified
0.631 0.369 0.000
M02 Reactive arthropathies
0.630 0.370 0.000
Y48 Anaesthetics and therapeutic gases
0.630 0.370 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.630 0.370 0.000
Q18 Other congenital malformations of face and neck
0.629 0.371 0.000
A80-A89 Viral infections of the central nervous system
0.628 0.372 0.000
A08 Viral and other specified intestinal infections
0.628 0.372 0.000
M46.8 Other specified inflammatory spondylopathies
0.627 0.372 0.000
M46.5 Other infective spondylopathies
0.627 0.372 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.627 0.372 0.000
M46.2 Osteomyelitis of vertebra
0.627 0.372 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.627 0.372 0.000
M46.0 Spinal enthesopathy
0.627 0.372 0.000
M46.4 Discitis, unspecified
0.627 0.373 0.000
H66 Suppurative and unspecified otitis media
0.626 0.374 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.626 0.374 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.626 0.374 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.626 0.374 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.625 0.375 0.000
D26 Other benign neoplasms of uterus
0.625 0.375 0.000
J37 Chronic laryngitis and laryngotracheitis
0.624 0.376 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.624 0.376 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.624 0.376 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.622 0.378 0.000
M89 Other disorders of bone
0.621 0.379 0.000
J32.4 Chronic pansinusitis
0.621 0.379 0.000
B35 Dermatophytosis
0.621 0.379 0.000
F60 Specific personality disorders
0.620 0.380 0.000
Y45.2 Propionic acid derivatives
0.619 0.381 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.618 0.381 0.000
C43 Malignant melanoma of skin
0.618 0.382 0.000
D31 Benign neoplasm of eye and adnexa
0.617 0.383 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.617 0.383 0.000
O66 Other obstructed labour
0.616 0.383 0.000
D12.9 Anus and anal canal
0.616 0.384 0.000
J21 Acute bronchiolitis
0.615 0.385 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.615 0.385 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.614 0.386 0.000
L10-L14 Bullous disorders
0.614 0.386 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.613 0.387 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.613 0.387 0.000
H17 Corneal scars and opacities
0.613 0.387 0.000
H15 Disorders of sclera
0.613 0.387 0.000
H20.8 Other iridocyclitis
0.613 0.387 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.612 0.388 0.000
D16 Benign neoplasm of bone and articular cartilage
0.612 0.388 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.611 0.389 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.611 0.389 0.000
J32.3 Chronic sphenoidal sinusitis
0.611 0.389 0.000
J32.1 Chronic frontal sinusitis
0.611 0.389 0.000
H20.2 Lens-induced iridocyclitis
0.610 0.390 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.610 0.390 0.000
D30 Benign neoplasm of urinary organs
0.608 0.392 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.608 0.392 0.000
Q35-Q37 Cleft lip and cleft palate
0.608 0.392 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.608 0.392 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.607 0.393 0.000
J04 Acute laryngitis and tracheitis
0.607 0.393 0.000
J38.5 Laryngeal spasm
0.606 0.394 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.605 0.395 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.605 0.395 0.000
G92 Toxic encephalopathy
0.605 0.395 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.605 0.395 0.000
O00 Ectopic pregnancy
0.603 0.397 0.000
Q00-Q07 Congenital malformations of the nervous system
0.603 0.397 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.602 0.398 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.602 0.398 0.000
J38.0 Paralysis of vocal cords and larynx
0.601 0.399 0.000
O20 Haemorrhage in early pregnancy
0.600 0.400 0.000
M10.99 Gout, unspecified (Site unspecified)
0.599 0.401 0.000
D12.2 Ascending colon
0.599 0.401 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.598 0.402 0.000
O21 Excessive vomiting in pregnancy
0.598 0.402 0.000
O75.9 Complication of labour and delivery, unspecified
0.596 0.404 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.596 0.404 0.000
O75.4 Other complications of obstetric surgery and procedures
0.596 0.404 0.000
O75.3 Other infection during labour
0.596 0.404 0.000
O75.1 Shock during or following labour and delivery
0.596 0.404 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.595 0.404 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.595 0.405 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.594 0.406 0.000
H65 Nonsuppurative otitis media
0.594 0.406 0.000
O90 Complications of the puerperium, not elsewhere classified
0.593 0.407 0.000
D18 Haemangioma and lymphangioma, any site
0.593 0.407 0.000
J14 Pneumonia due to Haemophilus influenzae
0.593 0.407 0.000
Y35-Y36 Legal intervention and operations of war
0.592 0.408 0.000
Y10-Y34 Event of undetermined intent
0.592 0.408 0.000
X85-X99 Assault
0.592 0.408 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.592 0.408 0.000
X50-X57 Overexertion, travel and privation
0.592 0.408 0.000
X30-X39 Exposure to forces of nature
0.592 0.408 0.000
X20-X29 Contact with venomous animals and plants
0.592 0.408 0.000
X10-X19 Contact with heat and hot substances
0.592 0.408 0.000
X00-X09 Exposure to smoke, fire and flames
0.592 0.408 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.592 0.408 0.000
W75-W84 Other accidental threats to breathing
0.592 0.408 0.000
W65-W74 Accidental drowning and submersion
0.592 0.408 0.000
V98-V99 Other and unspecified transport accidents
0.592 0.408 0.000
V95-V97 Air and space transport accidents
0.592 0.408 0.000
V90-V94 Water transport accidents
0.592 0.408 0.000
V70-V79 Bus occupant injured in transport accident
0.592 0.408 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.592 0.408 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.592 0.408 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.592 0.408 0.000
V01-V09 Pedestrian injured in transport accident
0.592 0.408 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.591 0.408 0.000
H21 Other disorders of iris and ciliary body
0.590 0.409 0.000
C67.6 Ureteric orifice
0.590 0.410 0.000
O02 Other abnormal products of conception
0.589 0.411 0.000
O61 Failed induction of labour
0.588 0.411 0.000
O23 Infections of genito-urinary tract in pregnancy
0.588 0.411 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.588 0.411 0.000
G91.8 Other hydrocephalus
0.587 0.413 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.587 0.413 0.000
G91.2 Normal-pressure hydrocephalus
0.587 0.413 0.000
G91.0 Communicating hydrocephalus
0.587 0.413 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.587 0.413 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.586 0.414 0.000
O04 Medical abortion
0.586 0.414 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.586 0.414 0.000
O42 Premature rupture of membranes
0.586 0.414 0.000
Y59 Other and unspecified vaccines and biological substances
0.586 0.414 0.000
Y58 Bacterial vaccines
0.586 0.414 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.586 0.414 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.586 0.414 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.586 0.414 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.586 0.414 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.586 0.414 0.000
H60-H62 Diseases of external ear
0.586 0.414 0.000
G12 Spinal muscular atrophy and related syndromes
0.585 0.415 0.000
H90-H95 Other disorders of ear
0.585 0.415 0.000
H74 Other disorders of middle ear and mastoid
0.585 0.415 0.000
G03 Meningitis due to other and unspecified causes
0.584 0.415 0.000
V20-V29 Motorcycle rider injured in transport accident
0.584 0.416 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.584 0.416 0.000
O63 Long labour
0.583 0.417 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.583 0.417 0.000
Q12 Congenital lens malformations
0.583 0.417 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.583 0.417 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.583 0.417 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.583 0.417 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.583 0.417 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.583 0.417 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.583 0.417 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.583 0.417 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.583 0.417 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.583 0.417 0.000
G96 Other disorders of central nervous system
0.582 0.418 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.582 0.418 0.000
L03 Cellulitis
0.581 0.419 0.000
H40.0 Glaucoma suspect
0.581 0.419 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.580 0.420 0.000
L08 Other local infections of skin and subcutaneous tissue
0.580 0.420 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.579 0.421 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.579 0.421 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.579 0.421 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.579 0.421 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.579 0.421 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.579 0.421 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.579 0.421 0.000
M10.4 Other secondary gout
0.577 0.423 0.000
M10.3 Gout due to impairment of renal function
0.577 0.423 0.000
M10.2 Drug-induced gout
0.577 0.423 0.000
M10.1 Lead-induced gout
0.577 0.423 0.000
M10.0 Idiopathic gout
0.577 0.423 0.000
G60.0 Hereditary motor and sensory neuropathy
0.577 0.423 0.000
M40 Kyphosis and lordosis
0.577 0.423 0.000
H55 Nystagmus and other irregular eye movements
0.577 0.423 0.000
L40-L45 Papulosquamous disorders
0.576 0.424 0.000
W20-W49 Exposure to inanimate mechanical forces
0.576 0.424 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.575 0.425 0.000
D19 Benign neoplasm of mesothelial tissue
0.575 0.425 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.575 0.425 0.000
F81.9 Developmental disorder of scholastic skills, unspecified
0.575 0.425 0.000
W50-W64 Exposure to animate mechanical forces
0.575 0.425 0.000
G24.9 Dystonia, unspecified
0.575 0.425 0.000
O30 Multiple gestation
0.573 0.427 0.000
M87 Osteonecrosis
0.573 0.427 0.000
D11 Benign neoplasm of major salivary glands
0.573 0.427 0.000
D12.1 Appendix
0.573 0.427 0.000
G95 Other diseases of spinal cord
0.573 0.427 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.572 0.428 0.000
H10-H13 Disorders of conjunctiva
0.572 0.428 0.000
M06.34 Rheumatoid nodule (Hand)
0.572 0.428 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.571 0.429 0.000
H69 Other disorders of Eustachian tube
0.571 0.429 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.570 0.430 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.570 0.430 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.569 0.431 0.000
D12.6 Colon, unspecified
0.569 0.431 0.000
F10.3 Withdrawal state
0.568 0.432 0.000
C81.2 Mixed cellularity
0.568 0.432 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.567 0.433 0.000
B33 Other viral diseases, not elsewhere classified
0.567 0.433 0.000
B30 Viral conjunctivitis
0.567 0.433 0.000
B27 Infectious mononucleosis
0.567 0.433 0.000
B26 Mumps
0.567 0.433 0.000
B25 Cytomegaloviral disease
0.567 0.433 0.000
J15.2 Pneumonia due to staphylococcus
0.566 0.434 0.000
M80-M85 Disorders of bone density and structure
0.565 0.435 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.564 0.436 0.000
J17 Pneumonia in diseases classified elsewhere
0.564 0.436 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.564 0.436 0.000
J12 Viral pneumonia, not elsewhere classified
0.564 0.436 0.000
J09 Influenza due to certain identified influenza virus
0.564 0.436 0.000
L29 Pruritus
0.564 0.436 0.000
F38 Other mood [affective] disorders
0.563 0.436 0.000
F34 Persistent mood [affective] disorders
0.563 0.436 0.000
F30 Manic episode
0.563 0.436 0.000
F39 Unspecified mood [affective] disorder
0.563 0.436 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.563 0.436 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.563 0.436 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.563 0.436 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.563 0.436 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.563 0.436 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.563 0.436 0.000
H18 Other disorders of cornea
0.563 0.437 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.563 0.437 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.562 0.438 0.000
J38.4 Oedema of larynx
0.562 0.438 0.000
C81.0 Lymphocytic predominance
0.562 0.438 0.000
J01.0 Acute maxillary sinusitis
0.562 0.438 0.000
Y44 Agents primarily affecting blood constituents
0.561 0.439 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.560 0.440 0.000
L03.3 Cellulitis of trunk
0.560 0.440 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.559 0.441 0.000
Y45.8 Other analgesics and antipyretics
0.559 0.441 0.000
Y45.5 4-Aminophenol derivatives
0.559 0.441 0.000
Y45.4 Antirheumatics
0.559 0.441 0.000
O87 Venous complications in the puerperium
0.559 0.441 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.558 0.442 0.000
C95 Leukaemia of unspecified cell type
0.558 0.442 0.000
C94 Other leukaemias of specified cell type
0.558 0.442 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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