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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2244027
log Bayes Factor = 8.8769
Chromosome 6   position 31,347,566  (GRCh37) Explore rs2244027 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.999 0.001 0.000
E10.9 Without complications
0.998 0.002 0.000
E10.3 With ophthalmic complications
0.992 0.008 0.000
E10.4 With neurological complications
0.973 0.027 0.000
E10.1 With ketoacidosis
0.895 0.105 0.000
E10.0 With coma
0.891 0.109 0.000
E10.2 With renal complications
0.860 0.140 0.000
K50.9 Crohn's disease, unspecified
0.814 0.186 0.000
K50 Crohn's disease [regional enteritis]
0.784 0.216 0.000
E10.8 With unspecified complications
0.776 0.224 0.000
E10.5 With peripheral circulatory complications
0.770 0.230 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.247 0.753
K50.1 Crohn's disease of large intestine
0.751 0.249 0.000
K50.0 Crohn's disease of small intestine
0.747 0.253 0.000
E10.6 With other specified complications
0.742 0.258 0.000
E10.7 With multiple complications
0.716 0.284 0.000
M45 Ankylosing spondylitis
0.000 0.286 0.714
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.327 0.673
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.329 0.671
K50.8 Other Crohn's disease
0.520 0.480 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.488 0.512
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.488 0.512
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.488 0.512
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.488 0.512
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.488 0.512
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.488 0.512
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.488 0.512
E10-E14 Diabetes mellitus
0.404 0.595 0.001
E03 Other hypothyroidism
0.001 0.627 0.372
E14 Unspecified diabetes mellitus
0.325 0.675 0.000
E13 Other specified diabetes mellitus
0.304 0.696 0.001
E12 Malnutrition-related diabetes mellitus
0.289 0.710 0.001
E03.5 Myxoedema coma
0.001 0.732 0.267
E03.4 Atrophy of thyroid (acquired)
0.001 0.732 0.267
E03.3 Postinfectious hypothyroidism
0.001 0.732 0.267
E14.6 With other specified complications
0.264 0.736 0.000
E14.1 With ketoacidosis
0.264 0.736 0.000
E14.2 Withrenal complications
0.260 0.740 0.000
E14.4 With neurological complications
0.257 0.743 0.000
E03.8 Other specified hypothyroidism
0.001 0.744 0.255
E03.0 Congenital hypothyroidism with diffuse goitre
0.001 0.745 0.254
E03.1 Congenital hypothyroidism without goitre
0.001 0.746 0.253
E14.8 With unspecified complications
0.251 0.749 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.001 0.753 0.246
E14.3 With ophthalmic complications
0.243 0.756 0.000
E14.7 With multiple complications
0.233 0.767 0.000
E14.0 With coma
0.233 0.767 0.000
E13.9 Without complications
0.232 0.767 0.000
E13.8 With unspecified complications
0.218 0.781 0.001
E13.7 With multiple complications
0.218 0.781 0.001
E13.6 With other specified complications
0.218 0.781 0.001
E13.5 With peripheral circulatory complications
0.218 0.781 0.001
E13.4 With neurological complications
0.218 0.781 0.001
E13.3 With ophthalmic complications
0.218 0.781 0.001
E13.2 With renal complications
0.218 0.781 0.001
E13.1 With ketoacidosis
0.218 0.781 0.001
E13.0 With coma
0.218 0.781 0.001
E12.9 Without complications
0.208 0.792 0.001
E12.8 With unspecified complications
0.208 0.792 0.001
E12.7 With multiple complications
0.208 0.792 0.001
E12.6 With other specified complications
0.208 0.792 0.001
E12.5 With peripheral circulatory complications
0.208 0.792 0.001
E12.4 With neurological complications
0.208 0.792 0.001
E12.3 With ophthalmic complications
0.208 0.792 0.001
E12.2 With renal complications
0.208 0.792 0.001
E12.1 With ketoacidosis
0.208 0.792 0.001
E12.0 With coma
0.208 0.792 0.001
E14.5 With peripheral circulatory complications
0.204 0.796 0.000
E11 Non-insulin-dependent diabetes mellitus
0.181 0.819 0.000
E11.0 With coma
0.166 0.834 0.000
E11.1 With ketoacidosis
0.166 0.834 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.838 0.162
E11.4 With neurological complications
0.146 0.854 0.000
E27 Other disorders of adrenal gland
0.001 0.854 0.146
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.857 0.143
E11.6 With other specified complications
0.135 0.865 0.000
E11.7 With multiple complications
0.130 0.870 0.000
E27.2 Addisonian crisis
0.000 0.873 0.126
E11.8 With unspecified complications
0.117 0.883 0.000
E00-E07 Disorders of thyroid gland
0.003 0.892 0.105
E27.5 Adrenomedullary hyperfunction
0.001 0.895 0.104
E27.0 Other adrenocortical overactivity
0.001 0.895 0.104
E27.8 Other specified disorders of adrenal gland
0.000 0.903 0.096
E27.9 Disorder of adrenal gland, unspecified
0.001 0.908 0.091
E11.2 With renal complications
0.091 0.909 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.914 0.085
E07 Other disorders of thyroid
0.001 0.916 0.082
E06 Thyroiditis
0.001 0.918 0.081
E02 Subclinical iodine-deficiency hypothyroidism
0.002 0.920 0.078
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.002 0.923 0.075
E00 Congenital iodine-deficiency syndrome
0.002 0.923 0.075
E07.8 Other specified disorders of thyroid
0.001 0.923 0.076
E06.3 Autoimmune thyroiditis
0.000 0.930 0.070
E14.9 Without complications
0.068 0.932 0.000
K50-K52 Noninfective enteritis and colitis
0.061 0.939 0.000
E07.1 Dyshormogenetic goitre
0.001 0.940 0.059
E07.0 Hypersecretion of calcitonin
0.001 0.940 0.059
E11.5 With peripheral circulatory complications
0.060 0.940 0.000
E06.5 Other chronic thyroiditis
0.001 0.941 0.058
E06.4 Drug-induced thyroiditis
0.001 0.941 0.058
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.001 0.941 0.058
E06.0 Acute thyroiditis
0.001 0.941 0.058
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.002 0.944 0.054
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.002 0.944 0.054
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.002 0.944 0.054
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.002 0.944 0.054
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.002 0.944 0.054
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.002 0.944 0.054
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.002 0.944 0.054
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.002 0.944 0.054
E06.1 Subacute thyroiditis
0.001 0.945 0.054
Chapter IV Endocrine, nutritional and metabolic diseases
0.028 0.946 0.026
E04 Other non-toxic goitre
0.000 0.946 0.053
E06.9 Thyroiditis, unspecified
0.001 0.950 0.049
E04.0 Non-toxic diffuse goitre
0.000 0.956 0.044
M45-M49 Spondylopathies
0.000 0.958 0.042
L40.9 Psoriasis, unspecified
0.000 0.959 0.041
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.027 0.960 0.013
E04.8 Other specified non-toxic goitre
0.000 0.961 0.038
E20-E35 Disorders of other endocrine glands
0.006 0.962 0.032
E40-E46 Malnutrition
0.023 0.963 0.013
E04.9 Non-toxic goitre, unspecified
0.000 0.964 0.036
E11.3 With ophthalmic complications
0.035 0.965 0.000
B37.8 Candidiasis of other sites
0.000 0.967 0.033
E65-E68 Obesity and other hyperalimentation
0.018 0.968 0.015
E05 Thyrotoxicosis [hyperthyroidism]
0.001 0.968 0.030
L40.5 Arthropathic psoriasis
0.000 0.968 0.032
E04.2 Non-toxic multinodular goitre
0.000 0.968 0.032
L40 Psoriasis
0.000 0.968 0.032
E28 Ovarian dysfunction
0.002 0.970 0.028
M49 Spondylopathies in diseases classified elsewhere
0.000 0.970 0.030
E16 Other disorders of pancreatic internal secretion
0.026 0.970 0.004
B37 Candidiasis
0.000 0.970 0.030
E15 Nondiabetic hypoglycaemic coma
0.019 0.971 0.010
E20 Hypoparathyroidism
0.004 0.972 0.024
B37.0 Candidal stomatitis
0.000 0.972 0.028
E26 Hyperaldosteronism
0.004 0.972 0.024
E35 Disorders of endocrine glands in diseases classified elsewhere
0.005 0.973 0.023
E32 Diseases of thymus
0.005 0.973 0.023
E31 Polyglandular dysfunction
0.005 0.973 0.023
E30 Disorders of puberty, not elsewhere classified
0.005 0.973 0.023
E28.3 Primary ovarian failure
0.001 0.973 0.026
E25 Adrenogenital disorders
0.005 0.973 0.022
E44 Protein-energy malnutrition of moderate and mild degree
0.017 0.973 0.010
E45 Retarded development following protein-energy malnutrition
0.017 0.973 0.010
E43 Unspecified severe protein-energy malnutrition
0.017 0.973 0.010
E42 Marasmic kwashiorkor
0.017 0.973 0.010
E41 Nutritional marasmus
0.017 0.973 0.010
E40 Kwashiorkor
0.017 0.973 0.010
E16.2 Hypoglycaemia, unspecified
0.026 0.974 0.000
L40.8 Other psoriasis
0.000 0.975 0.025
E34 Other endocrine disorders
0.004 0.975 0.020
B37.9 Candidiasis, unspecified
0.000 0.975 0.025
E46 Unspecified protein-energy malnutrition
0.020 0.975 0.005
E07.9 Disorder of thyroid, unspecified
0.001 0.976 0.023
L40.1 Generalised pustular psoriasis
0.000 0.976 0.024
E67 Other hyperalimentation
0.013 0.976 0.011
E68 Sequelae of hyperalimentation
0.013 0.976 0.011
B37.3 Candidiasis of vulva and vagina
0.000 0.977 0.023
E05.9 Thyrotoxicosis, unspecified
0.000 0.977 0.023
E05.5 Thyroid crisis or storm
0.001 0.977 0.022
E05.4 Thyrotoxicosis factitia
0.001 0.977 0.022
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.001 0.977 0.022
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.001 0.977 0.022
K90.0 Coeliac disease
0.000 0.977 0.023
E50-E64 Other nutritional deficiencies
0.014 0.977 0.009
L40.2 Acrodermatitis continua
0.000 0.977 0.023
E24 Cushing's syndrome
0.005 0.977 0.018
E16.0 Drug-induced hypoglycaemia without coma
0.020 0.977 0.002
E29 Testicular dysfunction
0.005 0.978 0.017
E28.9 Ovarian dysfunction, unspecified
0.002 0.978 0.020
E28.8 Other ovarian dysfunction
0.002 0.978 0.020
E28.1 Androgen excess
0.002 0.978 0.020
E28.0 Oestrogen excess
0.002 0.978 0.020
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.978 0.022
M49.4 Neuropathic spondylopathy
0.000 0.978 0.022
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.978 0.022
M49.2 Enterobacterial spondylitis
0.000 0.978 0.022
M49.1 Brucella spondylitis
0.000 0.978 0.022
M49.0 Tuberculosis of spine
0.000 0.978 0.022
E16.9 Disorder of pancreatic internal secretion, unspecified
0.019 0.978 0.003
E16.8 Other specified disorders of pancreatic internal secretion
0.019 0.978 0.003
E16.4 Abnormal secretion of gastrin
0.019 0.978 0.003
E16.3 Increased secretion of glucagon
0.019 0.978 0.003
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.978 0.021
B37.6 Candidal endocarditis
0.000 0.978 0.021
B37.5 Candidal meningitis
0.000 0.978 0.021
B37.1 Pulmonary candidiasis
0.000 0.978 0.021
E65 Localised adiposity
0.016 0.978 0.006
E16.1 Other hypoglycaemia
0.019 0.979 0.003
E20.9 Hypoparathyroidism, unspecified
0.002 0.979 0.019
M46 Other inflammatory spondylopathies
0.000 0.979 0.021
L40.4 Guttate psoriasis
0.000 0.979 0.021
B37.2 Candidiasis of skin and nail
0.000 0.979 0.021
B37.7 Candidal septicaemia
0.000 0.979 0.021
E20.8 Other hypoparathyroidism
0.003 0.979 0.018
E20.1 Pseudohypoparathyroidism
0.003 0.979 0.018
E20.0 Idiopathic hypoparathyroidism
0.003 0.979 0.018
E26.0 Primary hyperaldosteronism
0.002 0.980 0.018
L40.3 Pustulosis palmaris et plantaris
0.000 0.980 0.020
B37.4 Candidiasis of other urogenital sites
0.000 0.980 0.020
E26.9 Hyperaldosteronism, unspecified
0.003 0.980 0.017
E26.8 Other hyperaldosteronism
0.003 0.980 0.017
E26.1 Secondary hyperaldosteronism
0.003 0.980 0.017
E30.9 Disorder of puberty, unspecified
0.003 0.980 0.017
E30.8 Other disorders of puberty
0.003 0.980 0.017
E30.1 Precocious puberty
0.003 0.980 0.017
E30.0 Delayed puberty
0.003 0.980 0.017
E31.9 Polyglandular dysfunction, unspecified
0.003 0.980 0.017
E31.8 Other polyglandular dysfunction
0.003 0.980 0.017
E31.1 Polyglandular hyperfunction
0.003 0.980 0.017
E31.0 Autoimmune polyglandular failure
0.003 0.980 0.017
E32.9 Disease of thymus, unspecified
0.003 0.980 0.017
E32.8 Other diseases of thymus
0.003 0.980 0.017
E32.1 Abscess of thymus
0.003 0.980 0.017
E32.0 Persistent hyperplasia of thymus
0.003 0.980 0.017
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.003 0.980 0.017
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.003 0.980 0.017
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.003 0.980 0.017
E28.2 Polycystic ovarian syndrome
0.001 0.980 0.019
E25.9 Adrenogenital disorder, unspecified
0.003 0.981 0.016
E25.8 Other adrenogenital disorders
0.003 0.981 0.016
E34.8 Other specified endocrine disorders
0.002 0.981 0.017
E44.1 Mild protein-energy malnutrition
0.012 0.981 0.007
E44.0 Moderate protein-energy malnutrition
0.012 0.981 0.007
E23 Hypofunction and other disorders of pituitary gland
0.003 0.981 0.016
E22 Hyperfunction of pituitary gland
0.004 0.981 0.015
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.004 0.981 0.015
M35.0 Sicca syndrome [Sjogren]
0.000 0.982 0.018
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.982 0.017
E34.5 Androgen resistance syndrome
0.003 0.982 0.015
E34.4 Constitutional tall stature
0.003 0.982 0.015
E34.3 Short stature, not elsewhere classified
0.003 0.982 0.015
E34.2 Ectopic hormone secretion, not elsewhere classified
0.003 0.982 0.015
E34.1 Other hypersecretion of intestinal hormones
0.003 0.982 0.015
E04.1 Non-toxic single thyroid nodule
0.000 0.983 0.017
E67.8 Other specified hyperalimentation
0.009 0.983 0.008
E67.3 Hypervitaminosis D
0.009 0.983 0.008
E67.2 Megavitamin-B6 syndrome
0.009 0.983 0.008
E67.1 Hypercarotenaemia
0.009 0.983 0.008
E67.0 Hypervitaminosis A
0.009 0.983 0.008
M35 Other systemic involvement of connective tissue
0.000 0.983 0.017
E54 Ascorbic acid deficiency
0.012 0.983 0.006
M35.3 Polymyalgia rheumatica
0.000 0.983 0.017
E64 Sequelae of malnutrition and other nutritional deficiencies
0.010 0.983 0.006
E63 Other nutritional deficiencies
0.010 0.983 0.006
E56 Other vitamin deficiencies
0.010 0.983 0.006
E50 Vitamin A deficiency
0.010 0.983 0.006
E60 Dietary zinc deficiency
0.010 0.983 0.006
E59 Dietary selenium deficiency
0.010 0.983 0.006
E52 Niacin deficiency [pellagra]
0.010 0.983 0.006
E24.8 Other Cushing's syndrome
0.004 0.984 0.013
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.004 0.984 0.013
E24.3 Ectopic ACTH syndrome
0.004 0.984 0.013
E24.1 Nelson's syndrome
0.004 0.984 0.013
E51 Thiamine deficiency
0.010 0.984 0.007
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.000 0.984 0.016
E34.9 Endocrine disorder, unspecified
0.003 0.984 0.013
E58 Dietary calcium deficiency
0.010 0.984 0.007
E24.2 Drug-induced Cushing's syndrome
0.003 0.984 0.013
E29.9 Testicular dysfunction, unspecified
0.004 0.984 0.012
E29.8 Other testicular dysfunction
0.004 0.984 0.012
E29.0 Testicular hyperfunction
0.004 0.984 0.012
M35.7 Hypermobility syndrome
0.000 0.984 0.016
E24.0 Pituitary-dependent Cushing's disease
0.004 0.984 0.012
A63.0 Anogenital (venereal) warts
0.000 0.984 0.016
M49.09 Tuberculosis of spine (Site unspecified)
0.000 0.984 0.016
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.000 0.984 0.016
M49.07 Tuberculosis of spine (Lumbosacral region)
0.000 0.984 0.016
M49.06 Tuberculosis of spine (Lumbar region)
0.000 0.984 0.016
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.000 0.984 0.016
M49.04 Tuberculosis of spine (Thoracic region)
0.000 0.984 0.016
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.000 0.984 0.016
M49.02 Tuberculosis of spine (Cervical region)
0.000 0.984 0.016
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)
0.000 0.984 0.016
M49.00 Tuberculosis of spine (Multiple sites in spine)
0.000 0.984 0.016
M49.19 Brucella spondylitis (Site unspecified)
0.000 0.984 0.016
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)
0.000 0.984 0.016
M49.17 Brucella spondylitis (Lumbosacral region)
0.000 0.984 0.016
M49.16 Brucella spondylitis (Lumbar region)
0.000 0.984 0.016
M49.15 Brucella spondylitis (Thoracolumbar region)
0.000 0.984 0.016
M49.14 Brucella spondylitis (Thoracic region)
0.000 0.984 0.016
M49.13 Brucella spondylitis (Cervicothoracic region)
0.000 0.984 0.016
M49.12 Brucella spondylitis (Cervical region)
0.000 0.984 0.016
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)
0.000 0.984 0.016
M49.10 Brucella spondylitis (Multiple sites in spine)
0.000 0.984 0.016
M49.29 Enterobacterial spondylitis (Site unspecified)
0.000 0.984 0.016
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)
0.000 0.984 0.016
M49.27 Enterobacterial spondylitis (Lumbosacral region)
0.000 0.984 0.016
M49.26 Enterobacterial spondylitis (Lumbar region)
0.000 0.984 0.016
M49.25 Enterobacterial spondylitis (Thoracolumbar region)
0.000 0.984 0.016
M49.24 Enterobacterial spondylitis (Thoracic region)
0.000 0.984 0.016
M49.23 Enterobacterial spondylitis (Cervicothoracic region)
0.000 0.984 0.016
M49.22 Enterobacterial spondylitis (Cervical region)
0.000 0.984 0.016
M49.21 Enterobacterial spondylitis (Occipito-atlanto-axial region)
0.000 0.984 0.016
M49.20 Enterobacterial spondylitis (Multiple sites in spine)
0.000 0.984 0.016
M49.39 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Site unspecified)
0.000 0.984 0.016
M49.38 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.984 0.016
M49.37 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbosacral region)
0.000 0.984 0.016
M49.36 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbar region)
0.000 0.984 0.016
M49.35 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracolumbar region)
0.000 0.984 0.016
M49.34 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracic region)
0.000 0.984 0.016
M49.33 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervicothoracic region)
0.000 0.984 0.016
M49.32 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervical region)
0.000 0.984 0.016
M49.31 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.984 0.016
M49.30 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Multiple sites in spine)
0.000 0.984 0.016
M49.49 Neuropathic spondylopathy (Site unspecified)
0.000 0.984 0.016
M49.48 Neuropathic spondylopathy (Sacral and sacrococcygeal region)
0.000 0.984 0.016
M49.47 Neuropathic spondylopathy (Lumbosacral region)
0.000 0.984 0.016
M49.46 Neuropathic spondylopathy (Lumbar region)
0.000 0.984 0.016
M49.45 Neuropathic spondylopathy (Thoracolumbar region)
0.000 0.984 0.016
M49.44 Neuropathic spondylopathy (Thoracic region)
0.000 0.984 0.016
M49.43 Neuropathic spondylopathy (Cervicothoracic region)
0.000 0.984 0.016
M49.42 Neuropathic spondylopathy (Cervical region)
0.000 0.984 0.016
M49.41 Neuropathic spondylopathy (Occipito-atlanto-axial region)
0.000 0.984 0.016
M49.40 Neuropathic spondylopathy (Multiple sites in spine)
0.000 0.984 0.016
M49.89 Spondylopathy in other diseases classified elsewhere (Site unspecified)
0.000 0.984 0.016
M49.88 Spondylopathy in other diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.984 0.016
M49.87 Spondylopathy in other diseases classified elsewhere (Lumbosacral region)
0.000 0.984 0.016
M49.86 Spondylopathy in other diseases classified elsewhere (Lumbar region)
0.000 0.984 0.016
M49.85 Spondylopathy in other diseases classified elsewhere (Thoracolumbar region)
0.000 0.984 0.016
M49.84 Spondylopathy in other diseases classified elsewhere (Thoracic region)
0.000 0.984 0.016
M49.83 Spondylopathy in other diseases classified elsewhere (Cervicothoracic region)
0.000 0.984 0.016
M49.82 Spondylopathy in other diseases classified elsewhere (Cervical region)
0.000 0.984 0.016
M49.81 Spondylopathy in other diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.984 0.016
M49.80 Spondylopathy in other diseases classified elsewhere (Multiple sites in spine)
0.000 0.984 0.016
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)
0.000 0.984 0.016
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.984 0.016
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)
0.000 0.984 0.016
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)
0.000 0.984 0.016
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)
0.000 0.984 0.016
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)
0.000 0.984 0.016
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.984 0.016
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)
0.000 0.984 0.016
M46.0 Spinal enthesopathy
0.000 0.984 0.016
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.984 0.016
B35-B49 Mycoses
0.000 0.984 0.016
M46.8 Other specified inflammatory spondylopathies
0.000 0.984 0.015
M46.5 Other infective spondylopathies
0.000 0.984 0.015
M46.2 Osteomyelitis of vertebra
0.000 0.985 0.015
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)
0.000 0.985 0.015
M46.3 Infection of intervertebral disk (pyogenic)
0.000 0.985 0.015
M46.1 Sacro-iliitis, not elsewhere classified
0.000 0.985 0.014
E05.8 Other thyrotoxicosis
0.002 0.985 0.013
E55 Vitamin D deficiency
0.010 0.986 0.004
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.986 0.014
E61 Deficiency of other nutrient elements
0.009 0.986 0.005
E34.0 Carcinoid syndrome
0.004 0.986 0.010
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.002 0.986 0.011
E23.1 Drug-induced hypopituitarism
0.002 0.986 0.011
E22.9 Hyperfunction of pituitary gland, unspecified
0.003 0.986 0.011
E22.8 Other hyperfunction of pituitary gland
0.003 0.986 0.011
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.986 0.013
A30-A49 Other bacterial diseases
0.000 0.986 0.014
E23.6 Other disorders of pituitary gland
0.002 0.987 0.011
Chapter I Certain infectious and parasitic diseases
0.000 0.987 0.013
A41.8 Other specified septicaemia
0.000 0.987 0.013
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.000 0.987 0.013
E23.2 Diabetes insipidus
0.002 0.987 0.011
M35.8 Other specified systemic involvement of connective tissue
0.000 0.987 0.013
E66 Obesity
0.002 0.987 0.011
M48 Other spondylopathies
0.000 0.987 0.013
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.000 0.987 0.013
A41 Other septicaemia
0.000 0.987 0.013
N32.3 Diverticulum of bladder
0.013 0.987 0.000
A40 Streptococcal septicaemia
0.000 0.987 0.013
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.987 0.012
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.987 0.012
M35.5 Multifocal fibrosclerosis
0.000 0.987 0.012
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.987 0.012
M35.2 Behcet's disease
0.000 0.987 0.012
E24.9 Cushing's syndrome, unspecified
0.004 0.988 0.008
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.012 0.988 0.000
E50.9 Vitamin A deficiency, unspecified
0.008 0.988 0.005
E50.8 Other manifestations of vitamin A deficiency
0.008 0.988 0.005
E50.7 Other ocular manifestations of vitamin A deficiency
0.008 0.988 0.005
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.008 0.988 0.005
E50.5 Vitamin A deficiency with night blindness
0.008 0.988 0.005
E50.4 Vitamin A deficiency with keratomalacia
0.008 0.988 0.005
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.008 0.988 0.005
E50.2 Vitamin A deficiency with corneal xerosis
0.008 0.988 0.005
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.008 0.988 0.005
E50.0 Vitamin A deficiency with conjunctival xerosis
0.008 0.988 0.005
E56.9 Vitamin deficiency, unspecified
0.008 0.988 0.005
E56.8 Deficiency of other vitamins
0.008 0.988 0.005
E56.1 Deficiency of vitamin K
0.008 0.988 0.005
E56.0 Deficiency of vitamin E
0.008 0.988 0.005
E63.9 Nutritional deficiency, unspecified
0.008 0.988 0.005
E63.8 Other specified nutritional deficiencies
0.008 0.988 0.005
E63.1 Imbalance of constituents of food intake
0.008 0.988 0.005
E63.0 Essential fatty acid [EFA] deficiency
0.008 0.988 0.005
E64.9 Sequelae of unspecified nutritional deficiency
0.008 0.988 0.005
E64.8 Sequelae of other nutritional deficiencies
0.008 0.988 0.005
E64.3 Sequelae of rickets
0.008 0.988 0.005
E64.2 Sequelae of vitamin C deficiency
0.008 0.988 0.005
E64.1 Sequelae of vitamin A deficiency
0.008 0.988 0.005
E64.0 Sequelae of protein-energy malnutrition
0.008 0.988 0.005
E23.7 Disorder of pituitary gland, unspecified
0.003 0.988 0.010
E51.9 Thiamine deficiency, unspecified
0.007 0.988 0.005
E51.8 Other manifestations of thiamine deficiency
0.007 0.988 0.005
E51.1 Beriberi
0.007 0.988 0.005
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.988 0.012
E05.0 Thyrotoxicosis with diffuse goitre
0.001 0.988 0.011
K52 Other non-infective gastro-enteritis and colitis
0.012 0.988 0.000
M35.1 Other overlap syndromes
0.000 0.988 0.012
N32.8 Other specified disorders of bladder
0.012 0.988 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.000 0.988 0.012
M46.06 Spinal enthesopathy (Lumbar region)
0.000 0.988 0.012
L40.0 Psoriasis vulgaris
0.000 0.988 0.011
E53 Deficiency of other B group vitamins
0.007 0.988 0.005
E22.1 Hyperprolactinaemia
0.003 0.988 0.008
E51.2 Wernicke's encephalopathy
0.007 0.988 0.005
E22.0 Acromegaly and pituitary gigantism
0.003 0.988 0.009
M46.09 Spinal enthesopathy (Site unspecified)
0.000 0.988 0.011
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.000 0.988 0.011
M46.07 Spinal enthesopathy (Lumbosacral region)
0.000 0.988 0.011
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.000 0.988 0.011
M46.04 Spinal enthesopathy (Thoracic region)
0.000 0.988 0.011
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.000 0.988 0.011
M46.02 Spinal enthesopathy (Cervical region)
0.000 0.988 0.011
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.000 0.988 0.011
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.000 0.988 0.011
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.000 0.988 0.011
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.000 0.988 0.011
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.000 0.988 0.011
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.000 0.988 0.011
B48 Other mycoses, not elsewhere classified
0.000 0.988 0.011
B47 Mycetoma
0.000 0.988 0.011
B46 Zygomycosis
0.000 0.988 0.011
B45 Cryptococcosis
0.000 0.988 0.011
B43 Chromomycosis and phaeomycotic abscess
0.000 0.988 0.011
B42 Sporotrichosis
0.000 0.988 0.011
B41 Paracoccidioidomycosis
0.000 0.988 0.011
B40 Blastomycosis
0.000 0.988 0.011
B39 Histoplasmosis
0.000 0.988 0.011
B38 Coccidioidomycosis
0.000 0.988 0.011
B36 Other superficial mycoses
0.000 0.988 0.011
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.002 0.989 0.009
A48 Other bacterial diseases, not elsewhere classified
0.000 0.989 0.011
M46.59 Other infective spondylopathies (Site unspecified)
0.000 0.989 0.011
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M46.57 Other infective spondylopathies (Lumbosacral region)
0.000 0.989 0.011
M46.56 Other infective spondylopathies (Lumbar region)
0.000 0.989 0.011
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.000 0.989 0.011
M46.54 Other infective spondylopathies (Thoracic region)
0.000 0.989 0.011
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.000 0.989 0.011
M46.52 Other infective spondylopathies (Cervical region)
0.000 0.989 0.011
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.000 0.989 0.011
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.000 0.989 0.011
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.000 0.989 0.011
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.000 0.989 0.011
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.000 0.989 0.011
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.000 0.989 0.011
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.000 0.989 0.011
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)
0.000 0.989 0.011
M46.82 Other specified inflammatory spondylopathies (Cervical region)
0.000 0.989 0.011
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)
0.000 0.989 0.011
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)
0.000 0.989 0.011
N32.9 Bladder disorder, unspecified
0.011 0.989 0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.000 0.989 0.011
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.000 0.989 0.011
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.000 0.989 0.011
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.000 0.989 0.011
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.000 0.989 0.011
M46.22 Osteomyelitis of vertebra (Cervical region)
0.000 0.989 0.011
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.000 0.989 0.011
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.000 0.989 0.011
N32 Other disorders of bladder
0.011 0.989 0.000
A40.8 Other streptococcal septicaemia
0.000 0.989 0.011
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.000 0.989 0.011
B35 Dermatophytosis
0.000 0.989 0.011
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)
0.000 0.989 0.011
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)
0.000 0.989 0.011
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)
0.000 0.989 0.011
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)
0.000 0.989 0.011
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)
0.000 0.989 0.011
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)
0.000 0.989 0.011
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)
0.000 0.989 0.011
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)
0.000 0.989 0.011
E29.1 Testicular hypofunction
0.004 0.989 0.007
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.989 0.011
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.000 0.989 0.011
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.000 0.989 0.011
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.000 0.989 0.011
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.000 0.989 0.011
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.000 0.989 0.011
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.000 0.989 0.011
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.000 0.989 0.011
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.000 0.989 0.011
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.000 0.989 0.011
E66.8 Other obesity
0.000 0.989 0.011
A48.1 Legionnaires' disease
0.000 0.989 0.011
E55.0 Rickets, active
0.007 0.989 0.003
A63.8 Other specified predominantly sexually transmitted diseases
0.000 0.989 0.010
E61.9 Deficiency of nutrient element, unspecified
0.007 0.989 0.004
E61.8 Deficiency of other specified nutrient elements
0.007 0.989 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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