TreeWAS – Variant ID: rs2249031

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter II Neoplasms	0.998	0.002
Chapter I Certain infectious and parasitic diseases	0.997	0.003
A30-A49 Other bacterial diseases	0.993	0.007
Chapter IX Diseases of the circulatory system	0.992	0.008
A41 Other septicaemia	0.992	0.008
I30-I52 Other forms of heart disease	0.992	0.008
C15-C26 Malignant neoplasms of digestive organs	0.989	0.011
Chapter XV Pregnancy, childbirth and the puerperium	0.988	0.012
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.986	0.014
A41.9 Septicaemia, unspecified	0.985	0.015
I34 Nonrheumatic mitral valve disorders	0.977	0.023
S80-S89 Injuries to the knee and lower leg	0.975	0.025
T20-T25 Burns and corrosions of external body surface, specified by site	0.969	0.031
D37-D48 Neoplasms of uncertain or unknown behaviour	0.968	0.032
Chapter V Mental and behavioural disorders	0.962	0.038
Chapter XXI Factors influencing health status and contact with health services	0.957	0.043
S90-S99 Injuries to the ankle and foot	0.956	0.044
S81 Open wound of lower leg	0.955	0.045
I51 Complications and ill-defined descriptions of heart disease	0.949	0.051
I34.1 Mitral (valve) prolapse	0.947	0.053
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.939	0.061
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.937	0.063
C18 Malignant neoplasm of colon	0.931	0.069
F00-F09 Organic, including symptomatic, mental disorders	0.931	0.069
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.929	0.071
I42 Cardiomyopathy	0.919	0.081
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.917	0.083
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.914	0.086
I51.7 Cardiomegaly	0.911	0.089
I46 Cardiac arrest	0.908	0.092
C78.0 Secondary malignant neoplasm of lung	0.908	0.092
O20-O29 Other maternal disorders predominantly related to pregnancy	0.905	0.095
O94-O99 Other obstetric conditions, not elsewhere classified	0.904	0.096
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.900	0.100
C64-C68 Malignant neoplasms of urinary tract	0.896	0.104
S81.8 Open wound of other parts of lower leg	0.890	0.110
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.883	0.117
A41.1 Septicaemia due to other specified staphylococcus	0.883	0.117
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.880	0.120
F03 Unspecified dementia	0.874	0.126
M40-M43 Deforming dorsopathies	0.873	0.127
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.873	0.127
T15-T19 Effects of foreign body entering through natural orifice	0.873	0.127
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.869	0.131
M65-M68 Disorders of synovium and tendon	0.868	0.132
B35-B49 Mycoses	0.865	0.135
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.865	0.135
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.865	0.135
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.865	0.135
C16 Malignant neoplasm of stomach	0.861	0.138
C77.2 Intra-abdominal lymph nodes	0.861	0.139
F60-F69 Disorders of adult personality and behaviour	0.860	0.140
I44 Atrioventricular and left bundle-branch block	0.859	0.141
S81.9 Open wound of lower leg, part unspecified	0.854	0.146
T21 Burn and corrosion of trunk	0.854	0.146
Z40-Z54 Persons encountering health services for specific procedures and health care	0.852	0.148
S92 Fracture of foot, except ankle	0.851	0.149
C18.6 Descending colon	0.850	0.150
T79-T79 Certain early complications of trauma	0.846	0.154
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.844	0.156
D37.1 Stomach	0.843	0.157
C18.7 Sigmoid colon	0.843	0.157
Chapter VII Diseases of the eye and adnexa	0.842	0.158
Z35 Supervision of high-risk pregnancy	0.842	0.158
B95-B98 Bacterial, viral and other infectious agents	0.839	0.161
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.832	0.168
T90 Sequelae of injuries of head	0.832	0.168
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.832	0.168
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.831	0.169
I83 Varicose veins of lower extremities	0.830	0.170
I42.9 Cardiomyopathy, unspecified	0.826	0.174
O16 Unspecified maternal hypertension	0.824	0.176
I83.1 Varicose veins of lower extremities with inflammation	0.824	0.176
Z00-Z13 Persons encountering health services for examination and investigation	0.823	0.177
I34.0 Mitral (valve) insufficiency	0.822	0.178
Chapter XXII Codes for special purposes	0.820	0.180
O44 Placenta praevia	0.815	0.185
T66-T78 Other and unspecified effects of external causes	0.815	0.185
Z45 Adjustment and management of implanted device	0.813	0.187
S91 Open wound of ankle and foot	0.811	0.189
I70-I79 Diseases of arteries, arterioles and capillaries	0.810	0.190
M20-M25 Other joint disorders	0.809	0.191
M65 Synovitis and tenosynovitis	0.808	0.192
C18.8 Overlapping lesion of colon	0.807	0.193
F01 Vascular dementia	0.804	0.196
I37 Pulmonary valve disorders	0.802	0.197
O85-O92 Complications predominantly related to the puerperium	0.801	0.198
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.801	0.199
C77.9 Lymph node, unspecified	0.801	0.199
S81.0 Open wound of knee	0.800	0.200
A80-A89 Viral infections of the central nervous system	0.799	0.201
M43 Other deforming dorsopathies	0.796	0.204
C77.0 Lymph nodes of head, face and neck	0.796	0.204
I31 Other diseases of pericardium	0.793	0.207
C76 Malignant neoplasm of other and ill-defined sites	0.793	0.207
C21 Malignant neoplasm of anus and anal canal	0.792	0.208
Z33 Pregnant state, incidental	0.789	0.211
I05-I09 Chronic rheumatic heart diseases	0.788	0.212
M60-M63 Disorders of muscles	0.787	0.212
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.787	0.213
I50 Heart failure	0.785	0.215
I46.9 Cardiac arrest, unspecified	0.785	0.215
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.784	0.216
A41.5 Septicaemia due to other Gram-negative organisms	0.784	0.216
C78.7 Secondary malignant neoplasm of liver	0.783	0.217
I46.0 Cardiac arrest with successful resuscitation	0.783	0.217
S86 Injury of muscle and tendon at lower leg level	0.782	0.218
T31 Burns classified according to extent of body surface involved	0.782	0.218
T23 Burn and corrosion of wrist and hand	0.780	0.220
S99 Other and unspecified injuries of ankle and foot	0.779	0.221
C20 Malignant neoplasm of rectum	0.778	0.222
B15-B19 Viral hepatitis	0.778	0.222
S10-S19 Injuries to the neck	0.778	0.222
A41.8 Other specified septicaemia	0.776	0.224
T92 Sequelae of injuries of upper limb	0.776	0.224
I33 Acute and subacute endocarditis	0.775	0.225
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.775	0.225
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.775	0.225
O36 Maternal care for other known or suspected foetal problems	0.775	0.225
H20 Iridocyclitis	0.774	0.226
Z48 Other surgical follow-up care	0.773	0.227
T21.2 Burn of second degree of trunk	0.771	0.229
D48.1 Connective and other soft tissue	0.769	0.231
C67 Malignant neoplasm of bladder	0.769	0.231
T14 Injury of unspecified body region	0.769	0.231
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.768	0.232
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.768	0.232
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.764	0.236
C25 Malignant neoplasm of pancreas	0.762	0.238
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.762	0.238
A41.0 Septicaemia due to Staphylococcus aureus	0.762	0.238
O34 Maternal care for known or suspected abnormality of pelvic organs	0.761	0.239
A48 Other bacterial diseases, not elsewhere classified	0.761	0.239
Z35.0 Supervision of pregnancy with history of infertility	0.760	0.240
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.760	0.240
C79 Secondary malignant neoplasm of other sites	0.759	0.241
O23 Infections of genito-urinary tract in pregnancy	0.759	0.241
M24 Other specific joint derangements	0.757	0.243
M65.9 Synovitis and tenosynovitis, unspecified	0.757	0.243
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.756	0.244
F40-F48 Neurotic, stress-related and somatoform disorders	0.754	0.246
S89 Other and unspecified injuries of lower leg	0.752	0.248
S90 Superficial injury of ankle and foot	0.752	0.248
O20 Haemorrhage in early pregnancy	0.752	0.248
C16.0 Cardia	0.748	0.252
Z45.0 Adjustment and management of cardiac pacemaker	0.748	0.252
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.747	0.253
C17 Malignant neoplasm of small intestine	0.745	0.255
I34.2 Nonrheumatic mitral (valve) stenosis	0.745	0.255
F60 Specific personality disorders	0.744	0.256
M21 Other acquired deformities of limbs	0.743	0.257
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.743	0.257
C69 Malignant neoplasm of eye and adnexa	0.743	0.257
Chapter VI Diseases of the nervous system	0.742	0.258
H21 Other disorders of iris and ciliary body	0.741	0.259
H46-H48 Disorders of optic nerve and visual pathways	0.741	0.259
I51.0 Cardiac septal defect, acquired	0.739	0.261
Z35.1 Supervision of pregnancy with history of abortive outcome	0.739	0.261
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.738	0.262
T17 Foreign body in respiratory tract	0.737	0.263
I42.1 Obstructive hypertrophic cardiomyopathy	0.737	0.263
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.736	0.264
I36 Nonrheumatic tricuspid valve disorders	0.736	0.264
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.736	0.264
T79 Certain early complications of trauma, not elsewhere classified	0.736	0.264
C64 Malignant neoplasm of kidney, except renal pelvis	0.732	0.268
I30 Acute pericarditis	0.732	0.268
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.732	0.268
M00-M03 Infectious arthropathies	0.732	0.268
B35 Dermatophytosis	0.731	0.268
Z70-Z76 Persons encountering health services in other circumstances	0.730	0.270
I50.0 Congestive heart failure	0.729	0.271
O28 Abnormal findings on antenatal screening of mother	0.729	0.271
D37.6 Liver, gallbladder and bile ducts	0.728	0.272
C23 Malignant neoplasm of gallbladder	0.726	0.273
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.726	0.274
Z03 Medical observation and evaluation for suspected diseases and conditions	0.725	0.275
H18 Other disorders of cornea	0.723	0.277
B20-B24 Human immunodeficiency virus [HIV] disease	0.722	0.277
O44.1 Placenta praevia with haemorrhage	0.723	0.277
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.722	0.277
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.722	0.278
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.722	0.278
B49 Unspecified mycosis	0.722	0.278
I78 Diseases of capillaries	0.722	0.278
Z08 Follow-up examination after treatment for malignant neoplasm	0.722	0.278
Z45.1 Adjustment and management of infusion pump	0.721	0.279
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.721	0.279
C65 Malignant neoplasm of renal pelvis	0.721	0.279
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.720	0.280
Z47 Other orthopaedic follow-up care	0.720	0.280
I44.3 Other and unspecified atrioventricular block	0.719	0.281
D00-D09 In situ neoplasms	0.718	0.282
I44.7 Left bundle-branch block, unspecified	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
T31.0 Burns involving less than 10% of body surface	0.716	0.284
T91 Sequelae of injuries of neck and trunk	0.716	0.284
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284
F00 Dementia in Alzheimer's disease	0.715	0.284
M43.1 Spondylolisthesis	0.715	0.285
B99-B99 Other infectious diseases	0.715	0.285
B85-B89 Pediculosis, acariasis and other infestations	0.715	0.285
B50-B64 Protozoal diseases	0.715	0.285
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.715	0.285
A75-A79 Rickettsioses	0.715	0.285
A70-A74 Other diseases caused by chlamydiae	0.715	0.285
A65-A69 Other spirochaetal diseases	0.715	0.285
A20-A28 Certain zoonotic bacterial diseases	0.715	0.285
A15-A19 Tuberculosis	0.715	0.285
I31.9 Disease of pericardium, unspecified	0.714	0.286
D37.0 Lip, oral cavity and pharynx	0.713	0.287
C19 Malignant neoplasm of rectosigmoid junction	0.713	0.287
F01.9 Vascular dementia, unspecified	0.713	0.287
A44 Bartonellosis	0.712	0.288
A43 Nocardiosis	0.712	0.288
A42 Actinomycosis	0.712	0.288
A39 Meningococcal infection	0.712	0.288
A37 Whooping cough	0.712	0.288
A36 Diphtheria	0.712	0.288
A32 Listeriosis	0.712	0.288
A31 Infection due to other mycobacteria	0.712	0.288
A30 Leprosy [Hansen's disease]	0.712	0.288
A38 Scarlet fever	0.712	0.288
A35 Other tetanus	0.712	0.288
A34 Obstetrical tetanus	0.712	0.288
A33 Tetanus neonatorum	0.712	0.288
S40-S49 Injuries to the shoulder and upper arm	0.712	0.288
I00-I02 Acute rheumatic fever	0.711	0.289
M45-M49 Spondylopathies	0.711	0.289
A40 Streptococcal septicaemia	0.711	0.289
H20.9 Iridocyclitis, unspecified	0.711	0.289
A41.4 Septicaemia due to anaerobes	0.711	0.289
A41.3 Septicaemia due to Haemophilus influenzae	0.711	0.289
A41.2 Septicaemia due to unspecified staphylococcus	0.711	0.289
I52 Other heart disorders in diseases classified elsewhere	0.711	0.289
I48 Atrial fibrillation and flutter	0.711	0.289
I43 Cardiomyopathy in diseases classified elsewhere	0.711	0.289
I41 Myocarditis in diseases classified elsewhere	0.711	0.289
I40 Acute myocarditis	0.711	0.289
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.711	0.289
I32 Pericarditis in diseases classified elsewhere	0.711	0.289
B90-B94 Sequelae of infectious and parasitic diseases	0.710	0.290
C26 Malignant neoplasm of other and ill-defined digestive organs	0.709	0.291
M41 Scoliosis	0.709	0.291
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.708	0.292
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.707	0.293
F69 Unspecified disorder of adult personality and behaviour	0.707	0.293
T18 Foreign body in alimentary tract	0.706	0.294
C18.3 Hepatic flexure	0.705	0.295
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.703	0.297
F80-F89 Disorders of psychological development	0.702	0.298
I34.8 Other nonrheumatic mitral valve disorders	0.700	0.299
O26 Maternal care for other conditions predominantly related to pregnancy	0.700	0.300
C18.0 Caecum	0.700	0.300
D45 Polycythaemia vera	0.700	0.300
Z35.8 Supervision of other high-risk pregnancies	0.700	0.300
T14.0 Superficial injury of unspecified body region	0.700	0.300
A46 Erysipelas	0.700	0.300
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.700	0.300
D37.9 Digestive organ, unspecified	0.699	0.301
S88 Traumatic amputation of lower leg	0.699	0.301
S87 Crushing injury of lower leg	0.699	0.301
S85 Injury of blood vessels at lower leg level	0.699	0.301
S84 Injury of nerves at lower leg level	0.699	0.301
T90.8 Sequelae of other specified injuries of head	0.699	0.301
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.698	0.302
D48.6 Breast	0.698	0.302
S70-S79 Injuries to the hip and thigh	0.697	0.303
Z41 Procedures for purposes other than remedying health state	0.696	0.304
T25 Burn and corrosion of ankle and foot	0.695	0.305
T20 Burn and corrosion of head and neck	0.695	0.305
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.694	0.306
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.694	0.306
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.694	0.306
I42.0 Dilated cardiomyopathy	0.694	0.306
O44.0 Placenta praevia specified as without haemorrhage	0.694	0.306
D37.7 Other digestive organs	0.693	0.307
S82 Fracture of lower leg, including ankle	0.693	0.307
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.692	0.308
T90.2 Sequelae of fracture of skull and facial bones	0.691	0.309
C22.1 Intrahepatic bile duct carcinoma	0.690	0.310
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.690	0.310
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.690	0.310
I44.2 Atrioventricular block, complete	0.690	0.310
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.690	0.310
F70-F79 Mental retardation	0.690	0.310
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.690	0.310
G50-G59 Nerve, nerve root and plexus disorders	0.689	0.311
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.687	0.313
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.687	0.313
F99-F99 Unspecified mental disorder	0.686	0.314
C16.2 Body of stomach	0.686	0.314
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.686	0.314
S98 Traumatic amputation of ankle and foot	0.686	0.314
S97 Crushing injury of ankle and foot	0.686	0.314
S96 Injury of muscle and tendon at ankle and foot level	0.686	0.314
S95 Injury of blood vessels at ankle and foot level	0.686	0.314
S94 Injury of nerves at ankle and foot level	0.686	0.314
F02 Dementia in other diseases classified elsewhere	0.685	0.315
S92.0 Fracture of calcaneus	0.685	0.315
S81.7 Multiple open wounds of lower leg	0.685	0.315
Z13 Special screening examination for other diseases and disorders	0.684	0.316
S20-S29 Injuries to the thorax	0.683	0.316
D37.4 Colon	0.683	0.317
Z52 Donors of organs and tissues	0.683	0.317
Z03.4 Observation for suspected myocardial infarction	0.683	0.317
M21.2 Flexion deformity	0.682	0.317
O23.5 Infections of the genital tract in pregnancy	0.682	0.318
T78 Adverse effects, not elsewhere classified	0.682	0.318
I42.2 Other hypertrophic cardiomyopathy	0.682	0.318
I51.8 Other ill-defined heart diseases	0.682	0.318
Z48.8 Other specified surgical follow-up care	0.681	0.319
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.681	0.319
I51.6 Cardiovascular disease, unspecified	0.681	0.319
I51.5 Myocardial degeneration	0.681	0.319
I51.4 Myocarditis, unspecified	0.681	0.319
I51.3 Intracardiac thrombosis, not elsewhere classified	0.681	0.319
I51.2 Rupture of papillary muscle, not elsewhere classified	0.681	0.319
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.681	0.319
M62 Other disorders of muscle	0.680	0.320
S31 Open wound of abdomen, lower back and pelvis	0.680	0.320
O36.5 Maternal care for poor foetal growth	0.680	0.320
C78.4 Secondary malignant neoplasm of small intestine	0.680	0.320
T36-T50 Poisoning by drugs, medicaments and biological substances	0.679	0.320
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.679	0.321
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.679	0.321
O60-O75 Complications of labour and delivery	0.679	0.321
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.678	0.322
S92.3 Fracture of metatarsal bone	0.678	0.322
U51 Admission status on psychiatric patients	0.676	0.324
M67 Other disorders of synovium and tendon	0.676	0.324
T93 Sequelae of injuries of lower limb	0.676	0.324
I51.9 Heart disease, unspecified	0.674	0.326
Z31 Procreative management	0.674	0.326
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.674	0.326
C78.1 Secondary malignant neoplasm of mediastinum	0.674	0.326
S91.3 Open wound of other parts of foot	0.673	0.326
C71 Malignant neoplasm of brain	0.673	0.327
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.671	0.329
C67.9 Bladder, unspecified	0.671	0.329
C79.8 Secondary malignant neoplasm of other specified sites	0.670	0.330
S80 Superficial injury of lower leg	0.670	0.330
O48 Prolonged pregnancy	0.670	0.330
I44.6 Other and unspecified fascicular block	0.670	0.330
C80 Malignant neoplasm without specification of site	0.669	0.331
G35-G37 Demyelinating diseases of the central nervous system	0.669	0.331
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.669	0.331
F40 Phobic anxiety disorders	0.669	0.331
C18.1 Appendix	0.668	0.332
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.667	0.332
F09 Unspecified organic or symptomatic mental disorder	0.667	0.332
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.667	0.332
I37.1 Pulmonary valve insufficiency	0.667	0.333
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.667	0.333
I07 Rheumatic tricuspid valve diseases	0.667	0.333
G56 Mononeuropathies of upper limb	0.667	0.333
T95 Sequelae of burns, corrosions and frostbite	0.666	0.334
T94 Sequelae of injuries involving multiple and unspecified body regions	0.666	0.334
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.666	0.334
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.666	0.334
A50-A64 Infections with a predominantly sexual mode of transmission	0.666	0.334
M35 Other systemic involvement of connective tissue	0.664	0.336
Z13.9 Special screening examination, unspecified	0.663	0.337
O90 Complications of the puerperium, not elsewhere classified	0.663	0.337
O20.9 Haemorrhage in early pregnancy, unspecified	0.662	0.338
Z63 Other problems related to primary support group, including family circumstances	0.661	0.339
B65-B83 Helminthiases	0.660	0.339
T92.2 Sequelae of fracture at wrist and hand level	0.660	0.340
S32 Fracture of lumbar spine and pelvis	0.660	0.340
Z45.2 Adjustment and management of vascular access device	0.660	0.340
I42.8 Other cardiomyopathies	0.659	0.341
I42.7 Cardiomyopathy due to drugs and other external agents	0.659	0.341
I42.6 Alcoholic cardiomyopathy	0.659	0.341
I42.5 Other restrictive cardiomyopathy	0.659	0.341
I42.4 Endocardial fibroelastosis	0.659	0.341
I42.3 Endomyocardial (eosinophilic) disease	0.659	0.341
M43.16 Spondylolisthesis (Lumbar region)	0.659	0.341
I78.1 Naevus, nonneoplastic	0.658	0.342
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.657	0.343
O15 Eclampsia	0.657	0.343
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.657	0.343
C69.3 Choroid	0.656	0.344
D37.3 Appendix	0.655	0.345
D37.2 Small intestine	0.655	0.345
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.655	0.345
C76.0 Head, face and neck	0.655	0.345
H53-H54 Visual disturbances and blindness	0.655	0.345
M24.5 Contracture of joint	0.654	0.346
Z37 Outcome of delivery	0.653	0.347
H47 Other disorders of optic [2nd] nerve and visual pathways	0.652	0.348
S99.9 Unspecified injury of ankle and foot	0.652	0.348
S92.2 Fracture of other tarsal bone(s)	0.652	0.348
I74 Arterial embolism and thrombosis	0.651	0.349
G56.0 Carpal tunnel syndrome	0.651	0.349
I46.1 Sudden cardiac death, so described	0.651	0.349
I87 Other disorders of veins	0.651	0.349
O29 Complications of anaesthesia during pregnancy	0.649	0.351
O22 Venous complications in pregnancy	0.649	0.351
O25 Malnutrition in pregnancy	0.649	0.351
H21.8 Other specified disorders of iris and ciliary body	0.649	0.351
M40 Kyphosis and lordosis	0.649	0.351
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.648	0.352
O97 Death from sequelae of direct obstetric causes	0.648	0.352
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.648	0.352
O95 Obstetric death of unspecified cause	0.648	0.352
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.648	0.352
A81 Atypical virus infections of central nervous system	0.647	0.353
Z54 Convalescence	0.647	0.353
I70 Atherosclerosis	0.647	0.353
Z39 Postpartum care and examination	0.646	0.354
C49 Malignant neoplasm of other connective and soft tissue	0.646	0.354
M43.0 Spondylolysis	0.644	0.356
S92.5 Fracture of other toe	0.644	0.356
I05 Rheumatic mitral valve diseases	0.644	0.356
Chapter IV Endocrine, nutritional and metabolic diseases	0.644	0.356
H18.6 Keratoconus	0.644	0.356
S86.8 Injury of other muscles and tendons at lower leg level	0.643	0.356
Z42 Follow-up care involving plastic surgery	0.643	0.357
C68 Malignant neoplasm of other and unspecified urinary organs	0.642	0.358
M65.8 Other synovitis and tenosynovitis	0.641	0.358
S30 Superficial injury of abdomen, lower back and pelvis	0.641	0.359
M21.26 Flexion deformity (Lower leg)	0.639	0.361
S92.4 Fracture of great toe	0.639	0.361
C18.4 Transverse colon	0.637	0.362
O35 Maternal care for known or suspected foetal abnormality and damage	0.637	0.363
M70-M79 Other soft tissue disorders	0.637	0.363
S91.1 Open wound of toe(s) without damage to nail	0.636	0.364
F29 Unspecified nonorganic psychosis	0.636	0.364
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.635	0.365
B35.3 Tinea pedis	0.635	0.365
D46 Myelodysplastic syndromes	0.634	0.366
O45 Premature separation of placenta [abruptio placentae]	0.633	0.367
O33 Maternal care for known or suspected disproportion	0.633	0.367
O31 Complications specific to multiple gestation	0.633	0.367
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.632	0.368
B37 Candidiasis	0.632	0.368
D41.0 Kidney	0.632	0.368
M24.1 Other articular cartilage disorders	0.632	0.368
I45 Other conduction disorders	0.631	0.368
O21 Excessive vomiting in pregnancy	0.631	0.369
M91-M94 Chondropathies	0.631	0.369
Z38 Liveborn infants according to place of birth	0.631	0.369
H20.1 Chronic iridocyclitis	0.630	0.370
T90.4 Sequelae of injury of eye and orbit	0.629	0.370
C18.5 Splenic flexure	0.628	0.372
M15-M19 Arthrosis	0.627	0.373
C21.0 Anus, unspecified	0.627	0.373
M25 Other joint disorders, not elsewhere classified	0.626	0.374
M42 Spinal osteochondrosis	0.626	0.374
T32 Corrosions classified according to extent of body surface involved	0.626	0.374
T30 Burn and corrosion, body region unspecified	0.626	0.374
T29 Burns and corrosions of multiple body regions	0.626	0.374
T98 Sequelae of other and unspecified effects of external causes	0.626	0.374
T19 Foreign body in genito-urinary tract	0.626	0.374
T15 Foreign body on external eye	0.626	0.374
T16 Foreign body in ear	0.626	0.374
E20-E35 Disorders of other endocrine glands	0.625	0.375
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.623	0.377
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.623	0.377
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.623	0.377
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.623	0.377
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.623	0.377
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.623	0.377
C77.4 Inguinal and lower limb lymph nodes	0.622	0.378
Z43 Attention to artificial openings	0.622	0.378
Z47.8 Other specified orthopaedic follow-up care	0.621	0.379
B48 Other mycoses, not elsewhere classified	0.620	0.379
B47 Mycetoma	0.620	0.379
B46 Zygomycosis	0.620	0.379
B45 Cryptococcosis	0.620	0.379
B43 Chromomycosis and phaeomycotic abscess	0.620	0.379
B42 Sporotrichosis	0.620	0.379
B41 Paracoccidioidomycosis	0.620	0.379
B40 Blastomycosis	0.620	0.379
B39 Histoplasmosis	0.620	0.379
B38 Coccidioidomycosis	0.620	0.379
B36 Other superficial mycoses	0.620	0.379
T13 Other injuries of lower limb, level unspecified	0.620	0.379
T11 Other injuries of upper limb, level unspecified	0.620	0.379
T09 Other injuries of spine and trunk, level unspecified	0.620	0.379
T12.X1 Fracture of lower limb, level unspecified (open)	0.620	0.379
T12.X0 Fracture of lower limb, level unspecified (closed)	0.620	0.379
T12 Fracture of lower limb, level unspecified	0.620	0.379
T10.X1 Fracture of upper limb, level unspecified (open)	0.620	0.379
T10.X0 Fracture of upper limb, level unspecified (closed)	0.620	0.379
T10 Fracture of upper limb, level unspecified	0.620	0.379
T08.X1 Fracture of spine, level unspecified (open)	0.620	0.379
T08.X0 Fracture of spine, level unspecified (closed)	0.620	0.379
T08 Fracture of spine, level unspecified	0.620	0.379
S00-S09 Injuries to the head	0.620	0.379
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.620	0.380
C70 Malignant neoplasm of meninges	0.620	0.380
I33.0 Acute and subacute infective endocarditis	0.620	0.380
T23.0 Burn of unspecified degree of wrist and hand	0.620	0.380
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.620	0.380

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations