TreeWAS – Variant ID: rs2250245

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N64.5 Other signs and symptoms in breast	0.022	0.978	0.000
Z34.8 Supervision of other normal pregnancy	0.021	0.979	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.019	0.981	0.000
Z34 Supervision of normal pregnancy	0.018	0.982	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.018	0.982	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.017	0.983	0.000
N39.3 Stress incontinence	0.000	0.984	0.016
M17.0 Primary gonarthrosis, bilateral	0.015	0.985	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.013	0.987	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.987	0.013
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.012	0.988	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.012	0.988	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.988	0.012
I08 Multiple valve diseases	0.000	0.989	0.011
G58.9 Mononeuropathy, unspecified	0.011	0.989	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.011	0.989	0.000
Z34.0 Supervision of normal first pregnancy	0.011	0.989	0.000
Q54 Hypospadias	0.011	0.989	0.000
Q54.0 Hypospadias, balanic	0.011	0.989	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.011	0.989	0.000
Q80-Q89 Other congenital malformations	0.011	0.989	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.989	0.011
Q89 Other congenital malformations, not elsewhere classified	0.011	0.989	0.000
Q50-Q56 Congenital malformations of genital organs	0.010	0.989	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
Q54.9 Hypospadias, unspecified	0.010	0.990	0.000
Q89.2 Congenital malformations of other endocrine glands	0.010	0.990	0.000
Q51 Congenital malformations of uterus and cervix	0.010	0.990	0.000
Q28 Other congenital malformations of circulatory system	0.010	0.990	0.000
Q82 Other congenital malformations of skin	0.010	0.990	0.000
Q51.3 Bicornate uterus	0.010	0.990	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.009	0.991	0.000
M54.22 Cervicalgia (Cervical region)	0.000	0.991	0.009
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O46.9 Antepartum haemorrhage, unspecified	0.009	0.991	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.009	0.991	0.000
Q89.3 Situs inversus	0.009	0.991	0.000
Q82.8 Other specified congenital malformations of skin	0.009	0.991	0.000
R47.0 Dysphasia and aphasia	0.000	0.991	0.009
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.009	0.991	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.991	0.009
Q54.1 Hypospadias, penile	0.008	0.991	0.000
Q83 Congenital malformations of breast	0.008	0.991	0.000
Q82.5 Congenital nonneoplastic naevus	0.008	0.991	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.992	0.008
Q23 Congenital malformations of aortic and mitral valves	0.008	0.992	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.008	0.992	0.000
Q54.8 Other hypospadias	0.008	0.992	0.000
Q54.4 Congenital chordee	0.008	0.992	0.000
Q54.3 Hypospadias, perineal	0.008	0.992	0.000
Q54.2 Hypospadias, penoscrotal	0.008	0.992	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.992	0.008
Q87.4 Marfan's syndrome	0.008	0.992	0.000
Q53 Undescended testicle	0.008	0.992	0.000
Q55 Other congenital malformations of male genital organs	0.008	0.992	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.008	0.992	0.000
Q84 Other congenital malformations of integument	0.008	0.992	0.000
Q81 Epidermolysis bullosa	0.008	0.992	0.000
Q80 Congenital ichthyosis	0.008	0.992	0.000
N64 Other disorders of breast	0.008	0.992	0.000
Q89.9 Congenital malformation, unspecified	0.008	0.992	0.000
Q89.8 Other specified congenital malformations	0.008	0.992	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.008	0.992	0.000
Q89.4 Conjoined twins	0.008	0.992	0.000
Q89.1 Congenital malformations of adrenal gland	0.008	0.992	0.000
Q89.0 Congenital malformations of spleen	0.008	0.992	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.008	0.992	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.008	0.992	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.008	0.992	0.000
Q52 Other congenital malformations of female genitalia	0.008	0.992	0.000
Q51.2 Other doubling of uterus	0.008	0.992	0.000
Q82.0 Hereditary lymphoedema	0.007	0.992	0.000
Q51.4 Unicornate uterus	0.007	0.992	0.000
Q23.0 Congenital stenosis of aortic valve	0.007	0.992	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.007	0.993	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.007	0.993	0.000
Q51.6 Embryonic cyst of cervix	0.007	0.993	0.000
Q51.5 Agenesis and aplasia of cervix	0.007	0.993	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.007	0.993	0.000
Q51.0 Agenesis and aplasia of uterus	0.007	0.993	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.007	0.993	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.007	0.993	0.000
Q28.3 Other malformations of cerebral vessels	0.007	0.993	0.000
Q28.1 Other malformations of precerebral vessels	0.007	0.993	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.007	0.993	0.000
Q82.9 Congenital malformation of skin, unspecified	0.007	0.993	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.007	0.993	0.000
Q82.3 Incontinentia pigmenti	0.007	0.993	0.000
Q82.1 Xeroderma pigmentosum	0.007	0.993	0.000
R47.1 Dysarthria and anarthria	0.000	0.993	0.007
Q25 Congenital malformations of great arteries	0.007	0.993	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.007	0.993	0.000
N64.1 Fat necrosis of breast	0.007	0.993	0.000
Q23.1 Congenital insufficiency of aortic valve	0.007	0.993	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.007	0.993	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.007	0.993	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.007	0.993	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.007	0.993	0.000
O46.8 Other antepartum haemorrhage	0.007	0.993	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.007	0.993	0.000
Q83.1 Accessory breast	0.007	0.993	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.993	0.007
Q85 Phakomatoses, not elsewhere classified	0.007	0.993	0.000
Q82.2 Mastocytosis	0.007	0.993	0.000
Q26 Congenital malformations of great veins	0.007	0.993	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.007	0.993	0.000
I08.8 Other multiple valve diseases	0.000	0.993	0.007
Q35-Q37 Cleft lip and cleft palate	0.007	0.993	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.006	0.993	0.000
Q83.8 Other congenital malformations of breast	0.006	0.994	0.000
Q83.9 Congenital malformation of breast, unspecified	0.006	0.994	0.000
Q83.3 Accessory nipple	0.006	0.994	0.000
Q83.2 Absent nipple	0.006	0.994	0.000
Q83.0 Congenital absence of breast with absent nipple	0.006	0.994	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.006	0.994	0.000
Q27 Other congenital malformations of peripheral vascular system	0.006	0.994	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.006	0.994	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.006	0.994	0.000
Q23.4 Hypoplastic left heart syndrome	0.006	0.994	0.000
Q23.3 Congenital mitral insufficiency	0.006	0.994	0.000
Q23.2 Congenital mitral stenosis	0.006	0.994	0.000
Q53.1 Undescended testicle, unilateral	0.006	0.994	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.006	0.994	0.000
Q55.6 Other congenital malformations of penis	0.006	0.994	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.006	0.994	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.006	0.994	0.000
N89 Other noninflammatory disorders of vagina	0.000	0.994	0.006
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
N89.6 Tight hymenal ring	0.000	0.994	0.006
Q53.9 Undescended testicle, unspecified	0.006	0.994	0.000
Q53.2 Undescended testicle, bilateral	0.006	0.994	0.000
Q53.0 Ectopic testis	0.006	0.994	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.006	0.994	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.006	0.994	0.000
Q55.5 Congenital absence and aplasia of penis	0.006	0.994	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.006	0.994	0.000
Q55.3 Atresia of vas deferens	0.006	0.994	0.000
Q55.1 Hypoplasia of testis and scrotum	0.006	0.994	0.000
Q55.0 Absence and aplasia of testis	0.006	0.994	0.000
Q80.9 Congenital ichthyosis, unspecified	0.006	0.994	0.000
Q80.8 Other congenital ichthyosis	0.006	0.994	0.000
Q80.4 Harlequin foetus	0.006	0.994	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.006	0.994	0.000
Q80.2 Lamellar ichthyosis	0.006	0.994	0.000
Q80.1 X-linked ichthyosis	0.006	0.994	0.000
Q80.0 Ichthyosis vulgaris	0.006	0.994	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.006	0.994	0.000
Q81.8 Other epidermolysis bullosa	0.006	0.994	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.006	0.994	0.000
Q81.1 Epidermolysis bullosa letalis	0.006	0.994	0.000
Q81.0 Epidermolysis bullosa simplex	0.006	0.994	0.000
Q84.9 Congenital malformation of integument, unspecified	0.006	0.994	0.000
Q84.8 Other specified congenital malformations of integument	0.006	0.994	0.000
Q84.6 Other congenital malformations of nails	0.006	0.994	0.000
Q84.5 Enlarged and hypertrophic nails	0.006	0.994	0.000
Q84.4 Congenital leukonychia	0.006	0.994	0.000
Q84.3 Anonychia	0.006	0.994	0.000
Q84.2 Other congenital malformations of hair	0.006	0.994	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.006	0.994	0.000
Q84.0 Congenital alopecia	0.006	0.994	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.006	0.994	0.000
Q86.2 Dysmorphism due to warfarin	0.006	0.994	0.000
Q86.1 Foetal hydantoin syndrome	0.006	0.994	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.006	0.994	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.006	0.994	0.000
Q00-Q07 Congenital malformations of the nervous system	0.006	0.994	0.000
Q21 Congenital malformations of cardiac septa	0.006	0.994	0.000
N64.3 Galactorrhoea not associated with childbirth	0.006	0.994	0.000
N64.2 Atrophy of breast	0.006	0.994	0.000
N64.0 Fissure and fistula of nipple	0.006	0.994	0.000
O97 Death from sequelae of direct obstetric causes	0.006	0.994	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.006	0.994	0.000
O95 Obstetric death of unspecified cause	0.006	0.994	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.006	0.994	0.000
Q25.3 Stenosis of aorta	0.006	0.994	0.000
Q56.4 Indeterminate sex, unspecified	0.006	0.994	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.006	0.994	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.006	0.994	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.006	0.994	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.006	0.994	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.006	0.994	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.006	0.994	0.000
Q52.7 Other congenital malformations of vulva	0.006	0.994	0.000
Q52.6 Congenital malformation of clitoris	0.006	0.994	0.000
Q52.4 Other congenital malformations of vagina	0.006	0.994	0.000
Q52.3 Imperforate hymen	0.006	0.994	0.000
Q52.2 Congenital rectovaginal fistula	0.006	0.994	0.000
Q52.0 Congenital absence of vagina	0.006	0.994	0.000
G58 Other mononeuropathies	0.006	0.994	0.000
N89.5 Stricture and atresia of vagina	0.000	0.994	0.006
M54.2 Cervicalgia	0.000	0.994	0.006
Q52.5 Fusion of labia	0.006	0.994	0.000
Q52.1 Doubling of vagina	0.005	0.994	0.000
N64.4 Mastodynia	0.006	0.994	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.005	0.994	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.994	0.005
O46.0 Antepartum haemorrhage with coagulation defect	0.005	0.995	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.005	0.995	0.000
Q25.8 Other congenital malformations of great arteries	0.005	0.995	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.005	0.995	0.000
Q25.6 Stenosis of pulmonary artery	0.005	0.995	0.000
Q25.5 Atresia of pulmonary artery	0.005	0.995	0.000
Q25.4 Other congenital malformations of aorta	0.005	0.995	0.000
Q25.2 Atresia of aorta	0.005	0.995	0.000
Q25.0 Patent ductus arteriosus	0.005	0.995	0.000
Q22.1 Congenital pulmonary valve stenosis	0.005	0.995	0.000
Q25.1 Coarctation of aorta	0.005	0.995	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.005	0.995	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.005	0.995	0.000
Q22.6 Hypoplastic right heart syndrome	0.005	0.995	0.000
Q22.5 Ebstein's anomaly	0.005	0.995	0.000
Q22.4 Congenital tricuspid stenosis	0.005	0.995	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.005	0.995	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.005	0.995	0.000
Q22.0 Pulmonary valve atresia	0.005	0.995	0.000
M54.29 Cervicalgia-Site unspe	0.000	0.995	0.005
Q85.1 Tuberous sclerosis	0.005	0.995	0.000
I05 Rheumatic mitral valve diseases	0.000	0.995	0.005
Q37 Cleft palate with cleft lip	0.005	0.995	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.005	0.995	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.005	0.995	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.005	0.995	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
Q20.6 Isomerism of atrial appendages	0.005	0.995	0.000
Q20.5 Discordant atrioventricular connexion	0.005	0.995	0.000
Q20.4 Double inlet ventricle	0.005	0.995	0.000
Q20.3 Discordant ventriculoarterial connexion	0.005	0.995	0.000
Q20.2 Double outlet left ventricle	0.005	0.995	0.000
Q20.1 Double outlet right ventricle	0.005	0.995	0.000
Q20.0 Common arterial trunk	0.005	0.995	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.005	0.995	0.000
Q26.8 Other congenital malformations of great veins	0.005	0.995	0.000
Q26.6 Portal vein-hepatic artery fistula	0.005	0.995	0.000
Q26.5 Anomalous portal venous connexion	0.005	0.995	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.005	0.995	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.005	0.995	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.005	0.995	0.000
Q26.1 Persistent left superior vena cava	0.005	0.995	0.000
Q26.0 Congenital stenosis of vena cava	0.005	0.995	0.000
Q36 Cleft lip	0.005	0.995	0.000
Q35 Cleft palate	0.005	0.995	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.995	0.005
Q34 Other congenital malformations of respiratory system	0.005	0.995	0.000
Q33 Congenital malformations of lung	0.005	0.995	0.000
Q32 Congenital malformations of trachea and bronchus	0.005	0.995	0.000
Q31 Congenital malformations of larynx	0.005	0.995	0.000
Q30 Congenital malformations of nose	0.005	0.995	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.995	0.005
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
Q21.3 Tetralogy of Fallot	0.005	0.995	0.000
Q27.3 Peripheral arteriovenous malformation	0.005	0.995	0.000
Q50.5 Embryonic cyst of broad ligament	0.005	0.995	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.005	0.995	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.005	0.995	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.005	0.995	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.005	0.995	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.005	0.995	0.000
Q27.4 Congenital phlebectasia	0.005	0.995	0.000
Q27.2 Other congenital malformations of renal artery	0.005	0.995	0.000
Q27.1 Congenital renal artery stenosis	0.005	0.995	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.005	0.995	0.000
A04 Other bacterial intestinal infections	0.005	0.995	0.000
N64.9 Disorder of breast, unspecified	0.005	0.995	0.000
Q90 Down's syndrome	0.005	0.995	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.005	0.995	0.000
Q15 Other congenital malformations of eye	0.005	0.995	0.000
Q14 Congenital malformations of posterior segment of eye	0.005	0.995	0.000
Q13 Congenital malformations of anterior segment of eye	0.005	0.995	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.005	0.995	0.000
Q96 Turner's syndrome	0.005	0.995	0.000
G58.8 Other specified mononeuropathies	0.005	0.995	0.000
I05.0 Mitral stenosis	0.000	0.995	0.005
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.004	0.995	0.000
Q50.3 Other congenital malformations of ovary	0.004	0.995	0.000
Q50.2 Congenital torsion of ovary	0.004	0.995	0.000
Q50.1 Developmental ovarian cyst	0.004	0.995	0.000
Q50.0 Congenital absence of ovary	0.004	0.995	0.000
N89.7 Haematocolpos	0.000	0.995	0.005
N89.4 Leukoplakia of vagina	0.000	0.995	0.005
N89.3 Dysplasia of vagina, unspecified	0.000	0.995	0.005
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.000	0.995	0.005
N89.1 Moderate vaginal dysplasia	0.000	0.995	0.005
N89.0 Mild vaginal dysplasia	0.000	0.995	0.005
Q07 Other congenital malformations of nervous system	0.005	0.995	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.004	0.995	0.000
Q18 Other congenital malformations of face and neck	0.005	0.995	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
G58.7 Mononeuritis multiplex	0.004	0.995	0.000
Q06 Other congenital malformations of spinal cord	0.004	0.995	0.000
Q03 Congenital hydrocephalus	0.004	0.995	0.000
Q01 Encephalocele	0.004	0.995	0.000
Q00 Anencephaly and similar malformations	0.004	0.995	0.000
Q02 Microcephaly	0.004	0.995	0.000
Q21.8 Other congenital malformations of cardiac septa	0.004	0.995	0.000
Q21.4 Aortopulmonary septal defect	0.004	0.995	0.000
Q21.2 Atrioventricular septal defect	0.004	0.995	0.000
Q17 Other congenital malformations of ear	0.004	0.995	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.004	0.995	0.000
O96.9 Death from unspecified obstetric cause	0.004	0.995	0.000
O96.1 Death from indirect obstetric cause	0.004	0.995	0.000
O96.0 Death from direct obstetric cause	0.004	0.995	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.004	0.995	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.004	0.995	0.000
O97.0 Death from sequelae of direct obstetric cause	0.004	0.995	0.000
Q10.0 Congenital ptosis	0.004	0.995	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.000	0.996	0.004
G58.0 Intercostal neuropathy	0.004	0.996	0.000
B07 Viral warts	0.000	0.996	0.004
Q04 Other congenital malformations of brain	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.004	0.996	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.000	0.996	0.004
M54.27 Cervicalgia-Lumbosacral	0.000	0.996	0.004
M54.26 Cervicalgia-Lumbar	0.000	0.996	0.004
M54.25 Cervicalgia-Thoracolumbar	0.000	0.996	0.004
M54.24 Cervicalgia-Thoracic	0.000	0.996	0.004
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.000	0.996	0.004
M54.20 Cervicalgia-Mult site	0.000	0.996	0.004
Q99.8 Other specified chromosome abnormalities	0.004	0.996	0.000
A04.4 Other intestinal Escherichia coli infections	0.004	0.996	0.000
I06 Rheumatic aortic valve diseases	0.000	0.996	0.004
S72.00 Fracture of neck of femur (closed)	0.004	0.996	0.000
O66.4 Failed trial of labour, unspecified	0.004	0.996	0.000
F20.9 Schizophrenia, unspecified	0.000	0.996	0.004
I05.9 Mitral valve disease, unspecified	0.000	0.996	0.004
I05.2 Mitral stenosis with insufficiency	0.000	0.996	0.004
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
Q85.9 Phakomatosis, unspecified	0.004	0.996	0.000
Q21.0 Ventricular septal defect	0.004	0.996	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.004	0.996	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.004	0.996	0.000
I31.9 Disease of pericardium, unspecified	0.004	0.996	0.000
Q12 Congenital lens malformations	0.004	0.996	0.000
O66 Other obstructed labour	0.004	0.996	0.000
I05.8 Other mitral valve diseases	0.000	0.996	0.004
Q37.8 Unspecified cleft palate with bilateral cleft lip	0.004	0.996	0.000
Q37.5 Cleft hard and soft palate with unilateral cleft lip	0.004	0.996	0.000
Q37.4 Cleft hard and soft palate with bilateral cleft lip	0.004	0.996	0.000
Q37.3 Cleft soft palate with unilateral cleft lip	0.004	0.996	0.000
Q37.2 Cleft soft palate with bilateral cleft lip	0.004	0.996	0.000
Q37.1 Cleft hard palate with unilateral cleft lip	0.004	0.996	0.000
Q37.0 Cleft hard palate with bilateral cleft lip	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.996	0.004
Q10.7 Congenital malformation of orbit	0.004	0.996	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.004	0.996	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.004	0.996	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.004	0.996	0.000
Q10.3 Other congenital malformations of eyelid	0.004	0.996	0.000
Q10.2 Congenital entropion	0.004	0.996	0.000
Q10.1 Congenital ectropion	0.004	0.996	0.000
Q99.9 Chromosomal abnormality, unspecified	0.004	0.996	0.000
Q99.2 Fragile X chromosome	0.004	0.996	0.000
Q99.1 46,XX true hermaphrodite	0.004	0.996	0.000
Q99.0 Chimera 46,XX/46,XY	0.004	0.996	0.000
I09 Other rheumatic heart diseases	0.000	0.996	0.004
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.996	0.004
O66.0 Obstructed labour due to shoulder dystocia	0.004	0.996	0.000
Q35.9 Cleft palate, unspecified	0.004	0.996	0.000
Q35.8 (Cleft palate, unspecified, bilateral)	0.004	0.996	0.000
Q35.7 Cleft uvula	0.004	0.996	0.000
Q35.6 Cleft palate, medial	0.004	0.996	0.000
Q35.5 Cleft hard palate with cleft soft palate	0.004	0.996	0.000
Q35.4 (Cleft hard palate with cleft soft palate, bilateral)	0.004	0.996	0.000
Q35.3 Cleft soft palate	0.004	0.996	0.000
Q35.2 (Cleft soft palate, bilateral)	0.004	0.996	0.000
Q35.1 Cleft hard palate	0.004	0.996	0.000
Q35.0 (Cleft hard palate, bilateral)	0.004	0.996	0.000
Q36.9 Cleft lip, unilateral	0.004	0.996	0.000
Q36.1 Cleft lip, medial	0.004	0.996	0.000
Q36.0 Cleft lip, bilateral	0.004	0.996	0.000
Q05 Spina bifida	0.004	0.996	0.000
A04.9 Bacterial intestinal infection, unspecified	0.004	0.996	0.000
Q30.9 Congenital malformation of nose, unspecified	0.004	0.996	0.000
Q30.8 Other congenital malformations of nose	0.004	0.996	0.000
Q30.3 Congenital perforated nasal septum	0.004	0.996	0.000
Q30.2 Fissured, notched and cleft nose	0.004	0.996	0.000
Q30.1 Agenesis and underdevelopment of nose	0.004	0.996	0.000
Q30.0 Choanal atresia	0.004	0.996	0.000
Q31.9 Congenital malformation of larynx, unspecified	0.004	0.996	0.000
Q31.8 Other congenital malformations of larynx	0.004	0.996	0.000
Q31.5 Congenital laryngomalacia	0.004	0.996	0.000
Q31.4 Congenital laryngeal stridor	0.004	0.996	0.000
Q31.3 Laryngocele	0.004	0.996	0.000
Q31.2 Laryngeal hypoplasia	0.004	0.996	0.000
Q31.1 Congenital subglottic stenosis	0.004	0.996	0.000
Q31.0 Web of larynx	0.004	0.996	0.000
Q32.4 Other congenital malformations of bronchus	0.004	0.996	0.000
Q32.3 Congenital stenosis of bronchus	0.004	0.996	0.000
Q32.2 Congenital bronchomalacia	0.004	0.996	0.000
Q32.1 Other congenital malformations of trachea	0.004	0.996	0.000
Q32.0 Congenital tracheomalacia	0.004	0.996	0.000
Q33.9 Congenital malformation of lung, unspecified	0.004	0.996	0.000
Q33.8 Other congenital malformations of lung	0.004	0.996	0.000
Q33.6 Hypoplasia and dysplasia of lung	0.004	0.996	0.000
Q33.5 Ectopic tissue in lung	0.004	0.996	0.000
Q33.4 Congenital bronchiectasis	0.004	0.996	0.000
Q33.3 Agenesis of lung	0.004	0.996	0.000
Q33.2 Sequestration of lung	0.004	0.996	0.000
Q33.1 Accessory lobe of lung	0.004	0.996	0.000
Q33.0 Congenital cystic lung	0.004	0.996	0.000
Q34.9 Congenital malformation of respiratory system, unspecified	0.004	0.996	0.000
Q34.8 Other specified congenital malformations of respiratory system	0.004	0.996	0.000
Q34.1 Congenital cyst of mediastinum	0.004	0.996	0.000
Q34.0 Anomaly of pleura	0.004	0.996	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.996	0.004
Q24.6 Congenital heart block	0.003	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.996	0.000
Q24.2 Cor triatriatum	0.003	0.996	0.000
Q24.1 Levocardia	0.003	0.996	0.000
Q91.7 Patau's syndrome, unspecified	0.003	0.996	0.000
Q91.6 Trisomy 13, translocation	0.003	0.996	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.003	0.996	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.003	0.996	0.000
Q91.3 Edwards' syndrome, unspecified	0.003	0.996	0.000
Q91.2 Trisomy 18, translocation	0.003	0.996	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.003	0.996	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.003	0.996	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.003	0.996	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.003	0.996	0.000
Q92.7 Triploidy and polyploidy	0.003	0.996	0.000
Q92.6 Extra marker chromosomes	0.003	0.996	0.000
Q92.5 Duplications with other complex rearrangements	0.003	0.996	0.000
Q92.4 Duplications seen only at prometaphase	0.003	0.996	0.000
Q92.3 Minor partial trisomy	0.003	0.996	0.000
Q92.2 Major partial trisomy	0.003	0.996	0.000
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.003	0.996	0.000
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.003	0.996	0.000
Q93.9 Deletion from autosomes, unspecified	0.003	0.996	0.000
Q93.8 Other deletions from the autosomes	0.003	0.996	0.000
Q93.7 Deletions with other complex rearrangements	0.003	0.996	0.000
Q93.6 Deletions seen only at prometaphase	0.003	0.996	0.000
Q93.5 Other deletions of part of a chromosome	0.003	0.996	0.000
Q93.4 Deletion of short arm of chromosome 5	0.003	0.996	0.000
Q93.3 Deletion of short arm of chromosome 4	0.003	0.996	0.000
Q93.2 Chromosome replaced with ring or dicentric	0.003	0.996	0.000
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.003	0.996	0.000
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.003	0.996	0.000
Q95.9 Balanced rearrangement and structural marker, unspecified	0.003	0.996	0.000
Q95.8 Other balanced rearrangements and structural markers	0.003	0.996	0.000
Q95.5 Individuals with autosomal fragile site	0.003	0.996	0.000
Q95.4 Individuals with marker heterochromatin	0.003	0.996	0.000
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.003	0.996	0.000
Q95.2 Balanced autosomal rearrangement in abnormal individual	0.003	0.996	0.000
Q95.1 Chromosome inversion in normal individual	0.003	0.996	0.000
Q95.0 Balanced translocation and insertion in normal individual	0.003	0.996	0.000
Q97.9 Sex chromosome abnormality, female phenotype, unspecified	0.003	0.996	0.000
Q97.8 Other specified sex chromosome abnormalities, female phenotype	0.003	0.996	0.000
Q97.3 Female with 46,XY karyotype	0.003	0.996	0.000
Q97.2 Mosaicism, lines with various numbers of X chromosomes	0.003	0.996	0.000
Q97.1 Female with more than three X chromosomes	0.003	0.996	0.000
Q97.0 Karyotype 47,XXX	0.003	0.996	0.000
O16 Unspecified maternal hypertension	0.004	0.996	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.004	0.996	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.004	0.996	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.004	0.996	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.004	0.996	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.004	0.996	0.000
K81.1 Chronic cholecystitis	0.004	0.996	0.000
Q07.0 Arnold-Chiari syndrome	0.004	0.996	0.000
Q90.2 Trisomy 21, translocation	0.003	0.996	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.003	0.996	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.003	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
Q11.3 Macrophthalmos	0.003	0.996	0.000
Q11.2 Microphthalmos	0.003	0.996	0.000
Q11.1 Other anophthalmos	0.003	0.996	0.000
Q11.0 Cystic eyeball	0.003	0.996	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.003	0.996	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.003	0.996	0.000
Q13.5 Blue sclera	0.003	0.996	0.000
Q13.4 Other congenital corneal malformations	0.003	0.996	0.000
Q13.3 Congenital corneal opacity	0.003	0.996	0.000
Q13.2 Other congenital malformations of iris	0.003	0.996	0.000
Q13.1 Absence of iris	0.003	0.996	0.000
Q13.0 Coloboma of iris	0.003	0.996	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.003	0.996	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.003	0.996	0.000
Q14.3 Congenital malformation of choroid	0.003	0.996	0.000
Q14.2 Congenital malformation of optic disk	0.003	0.996	0.000
Q14.1 Congenital malformation of retina	0.003	0.996	0.000
Q14.0 Congenital malformation of vitreous humour	0.003	0.996	0.000
Q15.9 Congenital malformation of eye, unspecified	0.003	0.996	0.000
Q15.8 Other specified congenital malformations of eye	0.003	0.996	0.000
Q15.0 Congenital glaucoma	0.003	0.996	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations