TreeWAS – Variant ID: rs2251301

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H02.4 Ptosis of eyelid	0.000	0.954	0.046
H02.3 Blepharochalasis	0.000	0.956	0.044
H02 Other disorders of eyelid	0.000	0.961	0.039
H02.1 Ectropion of eyelid	0.000	0.967	0.033
H02.0 Entropion and trichiasis of eyelid	0.000	0.968	0.032
H02.7 Other degenerative disorders of eyelid and periocular area	0.000	0.972	0.028
H02.9 Disorder of eyelid, unspecified	0.000	0.972	0.028
H02.2 Lagophthalmos	0.000	0.972	0.028
O72.1 Other immediate postpartum haemorrhage	0.023	0.977	0.000
H02.6 Xanthelasma of eyelid	0.000	0.980	0.019
H02.5 Other disorders affecting eyelid function	0.000	0.981	0.019
S61.1 Open wound of finger(s) with damage to nail	0.016	0.984	0.000
O72 Postpartum haemorrhage	0.013	0.987	0.000
A08.4 Viral intestinal infection, unspecified	0.000	0.987	0.013
O72.0 Third-stage haemorrhage	0.009	0.991	0.000
E03.9 Hypothyroidism, unspecified	0.009	0.991	0.000
O72.3 Postpartum coagulation defects	0.009	0.991	0.000
O63.9 Long labour, unspecified	0.008	0.992	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.008	0.992	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.007	0.993	0.000
O60-O75 Complications of labour and delivery	0.007	0.993	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.007	0.993	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.993	0.007
O63 Long labour	0.007	0.993	0.000
O62 Abnormalities of forces of labour	0.007	0.993	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.006	0.994	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.006	0.994	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.006	0.994	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.006	0.994	0.000
O69.8 Labour and delivery complicated by other cord complications	0.006	0.994	0.000
O66 Other obstructed labour	0.006	0.994	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.006	0.994	0.000
E03 Other hypothyroidism	0.006	0.994	0.000
O64.1 Obstructed labour due to breech presentation	0.006	0.994	0.000
O62.1 Secondary uterine inertia	0.006	0.994	0.000
O74 Complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.006	0.994	0.000
O70.2 Third degree perineal laceration during delivery	0.006	0.994	0.000
O62.9 Abnormality of forces of labour, unspecified	0.006	0.994	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.005	0.994	0.000
O60 Preterm delivery	0.005	0.994	0.000
O64.5 Obstructed labour due to compound presentation	0.005	0.995	0.000
O64.4 Obstructed labour due to shoulder presentation	0.005	0.995	0.000
O64.3 Obstructed labour due to brow presentation	0.005	0.995	0.000
O64.2 Obstructed labour due to face presentation	0.005	0.995	0.000
O70 Perineal laceration during delivery	0.005	0.995	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.005	0.995	0.000
O71 Other obstetric trauma	0.005	0.995	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.005	0.995	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.005	0.995	0.000
O62.0 Primary inadequate contractions	0.005	0.995	0.000
O61 Failed induction of labour	0.005	0.995	0.000
O62.8 Other abnormalities of forces of labour	0.005	0.995	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.005	0.995	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.005	0.995	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.005	0.995	0.000
O47 False labour	0.005	0.995	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.005	0.995	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.005	0.995	0.000
O69.3 Labour and delivery complicated by short cord	0.005	0.995	0.000
O70.1 Second degree perineal laceration during delivery	0.005	0.995	0.000
O47.9 False labour, unspecified	0.005	0.995	0.000
E04.1 Non-toxic single thyroid nodule	0.005	0.995	0.000
O66.9 Obstructed labour, unspecified	0.004	0.995	0.000
O66.8 Other specified obstructed labour	0.004	0.995	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.004	0.995	0.000
O66.2 Obstructed labour due to unusually large foetus	0.004	0.995	0.000
O66.1 Obstructed labour due to locked twins	0.004	0.995	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.005	0.995	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.000	0.995	0.005
E03.5 Myxoedema coma	0.004	0.995	0.000
E03.4 Atrophy of thyroid (acquired)	0.004	0.995	0.000
E03.3 Postinfectious hypothyroidism	0.004	0.995	0.000
E03.1 Congenital hypothyroidism without goitre	0.004	0.995	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.004	0.995	0.000
O66.4 Failed trial of labour, unspecified	0.004	0.995	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.004	0.995	0.000
E03.8 Other specified hypothyroidism	0.005	0.995	0.000
A08 Viral and other specified intestinal infections	0.000	0.996	0.004
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.004	0.996	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.004	0.996	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.004	0.996	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.004	0.996	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.004	0.996	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.004	0.996	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.004	0.996	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.004	0.996	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.004	0.996	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.004	0.996	0.000
O63.0 Prolonged first stage (of labour)	0.004	0.996	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.996	0.004
O71.5 Other obstetric injury to pelvic organs	0.004	0.996	0.000
O60.3 Preterm delivery without spontaneous labour	0.004	0.996	0.000
O60.2 Preterm spontaneous labour with term delivery	0.004	0.996	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.004	0.996	0.000
O60.0 Preterm labour without delivery	0.004	0.996	0.000
O73 Retained placenta and membranes, without haemorrhage	0.004	0.996	0.000
O70.3 Fourth degree perineal laceration during delivery	0.004	0.996	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.004	0.996	0.000
O71.9 Obstetric trauma, unspecified	0.004	0.996	0.000
O71.7 Obstetric haematoma of pelvis	0.004	0.996	0.000
O71.3 Obstetric laceration of cervix	0.004	0.996	0.000
O71.2 Postpartum inversion of uterus	0.004	0.996	0.000
O71.1 Rupture of uterus during labour	0.004	0.996	0.000
O71.0 Rupture of uterus before onset of labour	0.004	0.996	0.000
O62.3 Precipitate labour	0.004	0.996	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.004	0.996	0.000
C61 Malignant neoplasm of prostate	0.000	0.996	0.004
O67.8 Other intrapartum haemorrhage	0.004	0.996	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.004	0.996	0.000
H34.8 Other retinal vascular occlusions	0.004	0.996	0.000
O61.9 Failed induction of labour, unspecified	0.004	0.996	0.000
O61.8 Other failed induction of labour	0.004	0.996	0.000
O61.1 Failed instrumental induction of labour	0.004	0.996	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.004	0.996	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.004	0.996	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.004	0.996	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.004	0.996	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.004	0.996	0.000
O65.0 Obstructed labour due to deformed pelvis	0.004	0.996	0.000
H01 Other inflammation of eyelid	0.000	0.996	0.004
I95.1 Orthostatic hypotension	0.000	0.996	0.004
O62.2 Other uterine inertia	0.004	0.996	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.004	0.996	0.000
H01.8 Other specified inflammation of eyelid	0.000	0.996	0.004
A08.3 Other viral enteritis	0.000	0.996	0.003
O69.2 Labour and delivery complicated by other cord entanglement	0.004	0.996	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.003	0.996	0.000
D37.7 Other digestive organs	0.004	0.996	0.000
O71.4 Obstetric high vaginal laceration alone	0.003	0.996	0.000
A08.5 Other specified intestinal infections	0.000	0.997	0.003
A08.2 Adenoviral enteritis	0.000	0.997	0.003
A08.0 Rotaviral enteritis	0.000	0.997	0.003
H00 Hordeolum and chalazion	0.000	0.997	0.003
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.997	0.003
H34.9 Retinal vascular occlusion, unspecified	0.003	0.997	0.000
O61.0 Failed medical induction of labour	0.003	0.997	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.003	0.997	0.000
O63.1 Prolonged second stage (of labour)	0.003	0.997	0.000
O70.9 Perineal laceration during delivery, unspecified	0.003	0.997	0.000
H05 Disorders of orbit	0.000	0.997	0.003
E05.9 Thyrotoxicosis, unspecified	0.000	0.997	0.003
H34 Retinal vascular occlusions	0.003	0.997	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.000	0.997	0.003
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.997	0.003
I21.2 Acute transmural myocardial infarction of other sites	0.003	0.997	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.997	0.003
H01.9 Inflammation of eyelid, unspecified	0.000	0.997	0.003
O47.0 False labour before 37 completed weeks of gestation	0.003	0.997	0.000
S52.6 Fracture of lower end of both ulna and radius	0.003	0.997	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.000	0.997	0.003
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.003	0.997	0.000
H01.1 Non-infectious dermatoses of eyelid	0.000	0.997	0.003
O71.8 Other specified obstetric trauma	0.003	0.997	0.000
H34.2 Other retinal artery occlusions	0.003	0.997	0.000
S00.8 Superficial injury of other parts of head	0.000	0.997	0.003
E07.9 Disorder of thyroid, unspecified	0.003	0.997	0.000
B02.9 Zoster without complication	0.000	0.997	0.003
E07 Other disorders of thyroid	0.003	0.997	0.000
H05.0 Acute inflammation of orbit	0.000	0.997	0.003
E00-E07 Disorders of thyroid gland	0.003	0.997	0.000
D47.1 Chronic myeloproliferative disease	0.003	0.997	0.000
D37.3 Appendix	0.003	0.997	0.000
D37.4 Colon	0.003	0.997	0.000
E04 Other non-toxic goitre	0.003	0.997	0.000
D59.1 Other autoimmune haemolytic anaemias	0.003	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.003	0.997	0.000
C71.9 Brain, unspecified	0.003	0.997	0.000
H05.9 Disorder of orbit, unspecified	0.000	0.997	0.002
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.000	0.997	0.002
H05.4 Enophthalmos	0.000	0.997	0.002
H05.3 Deformity of orbit	0.000	0.997	0.002
H05.1 Chronic inflammatory disorders of orbit	0.000	0.997	0.002
S52.61 Fracture of lower end of both ulna and radius (open)	0.003	0.997	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.003	0.997	0.000
H05.8 Other disorders of orbit	0.000	0.997	0.002
S52.80 Fracture of other parts of forearm (closed)	0.003	0.997	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.000	0.997	0.002
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.000	0.997	0.002
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.000	0.997	0.002
H34.0 Transient retinal artery occlusion	0.002	0.997	0.000
O42.9 Premature rupture of membranes, unspecified	0.003	0.997	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.997	0.003
H34.1 Central retinal artery occlusion	0.002	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.997	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.997	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.000	0.997	0.002
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.000	0.997	0.002
Y57.9 Drug or medicament, unspecified	0.002	0.997	0.000
S81.9 Open wound of lower leg, part unspecified	0.000	0.998	0.002
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.002	0.998	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.998	0.002
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
E07.1 Dyshormogenetic goitre	0.002	0.998	0.000
E07.0 Hypersecretion of calcitonin	0.002	0.998	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.002	0.998	0.000
D37.1 Stomach	0.002	0.998	0.000
H01.0 Blepharitis	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.002	0.998	0.000
C71.2 Temporal lobe	0.002	0.998	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E00 Congenital iodine-deficiency syndrome	0.002	0.998	0.000
S52.8 Fracture of other parts of forearm	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.998	0.002
E04.8 Other specified non-toxic goitre	0.002	0.998	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.002	0.998	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.998	0.002
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.002	0.998	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.002	0.998	0.000
H06.2 Dysthyroid exophthalmos	0.000	0.998	0.002
O36.6 Maternal care for excessive foetal growth	0.002	0.998	0.000
D37.2 Small intestine	0.002	0.998	0.000
M45 Ankylosing spondylitis	0.002	0.998	0.000
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.002	0.998	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.001	0.998	0.002
H05.2 Exophthalmic conditions	0.000	0.998	0.002
S52 Fracture of forearm	0.002	0.998	0.000
S62.61 Fracture of other finger (open)	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.998	0.002
C71.4 Occipital lobe	0.002	0.998	0.000
K63.9 Disease of intestine, unspecified	0.000	0.998	0.002
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.998	0.002
C71.7 Brain stem	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.998	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.998	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.998	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.998	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.998	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.998	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.998	0.000
S52.11 Fracture of upper end of radius (open)	0.002	0.998	0.000
O33.9 Maternal care for disproportion, unspecified	0.002	0.998	0.000
S52.81 Fracture of other parts of forearm (open)	0.002	0.998	0.000
S52.3 Fracture of shaft of radius	0.002	0.998	0.000
D37.6 Liver, gallbladder and bile ducts	0.002	0.998	0.000
S52.4 Fracture of shafts of both ulna and radius	0.002	0.998	0.000
S52.1 Fracture of upper end of radius	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
D37.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.002	0.998	0.000
H02.8 Other specified disorders of eyelid	0.000	0.998	0.002
O90.8 Other complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
S52.30 Fracture of shaft of radius (closed)	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.002	0.998	0.000
C43.5 Malignant melanoma of trunk	0.000	0.998	0.002
M06.0 Seronegative rheumatoid arthritis	0.000	0.998	0.002
E06 Thyroiditis	0.002	0.998	0.000
Z71.3 Dietary counselling and surveillance	0.002	0.998	0.000
O42 Premature rupture of membranes	0.002	0.998	0.000
O33 Maternal care for known or suspected disproportion	0.002	0.998	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.002	0.998	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.002	0.998	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.002	0.998	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.002	0.998	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.002	0.998	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
S52.9 Fracture of forearm, part unspecified	0.002	0.998	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.998	0.002
S52.7 Multiple fractures of forearm	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
S52.2 Fracture of shaft of ulna	0.002	0.998	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.001	0.998	0.001
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.002	0.998	0.000
S52.21 Fracture of shaft of ulna (open)	0.001	0.998	0.000
S52.31 Fracture of shaft of radius (open)	0.001	0.998	0.000
S52.41 Fracture of shafts of both ulna and radius (open)	0.001	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.002	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
E34 Other endocrine disorders	0.002	0.998	0.000
O36.4 Maternal care for intra-uterine death	0.002	0.998	0.000
O90.2 Haematoma of obstetric wound	0.002	0.998	0.000
O90.0 Disruption of Caesarean section wound	0.002	0.998	0.000
Z51.3 Blood transfusion without reported diagnosis	0.002	0.998	0.000
O40 Polyhydramnios	0.002	0.998	0.000
O75.9 Complication of labour and delivery, unspecified	0.001	0.998	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.001	0.998	0.000
O75.4 Other complications of obstetric surgery and procedures	0.001	0.998	0.000
O75.3 Other infection during labour	0.001	0.998	0.000
O75.1 Shock during or following labour and delivery	0.001	0.998	0.000
O44 Placenta praevia	0.002	0.998	0.000
O90 Complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.998	0.000
S92.51 Fracture of other toe (open)	0.001	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.001	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.998	0.000
O36 Maternal care for other known or suspected foetal problems	0.002	0.998	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.998	0.001
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.998	0.001
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.998	0.001
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.998	0.001
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.998	0.001
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.998	0.001
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.998	0.001
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.998	0.001
D03.7 Melanoma in situ of lower limb, including hip	0.000	0.998	0.002
E06.5 Other chronic thyroiditis	0.001	0.998	0.000
E06.4 Drug-induced thyroiditis	0.001	0.998	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.998	0.000
E06.1 Subacute thyroiditis	0.001	0.998	0.000
E06.0 Acute thyroiditis	0.001	0.998	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.002	0.998	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.001	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
O33.8 Maternal care for disproportion of other origin	0.001	0.998	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.001	0.998	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.001	0.998	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.001	0.998	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.001	0.998	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.001	0.998	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.001	0.998	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.001	0.998	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.001	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.001	0.998	0.000
S52.91 Fracture of forearm, part unspecified (open)	0.001	0.998	0.000
S52.90 Fracture of forearm, part unspecified (closed)	0.001	0.998	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.001	0.998	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.998	0.001
O36.1 Maternal care for other isoimmunisation	0.001	0.998	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
T51.0 Ethanol	0.000	0.998	0.001
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.999	0.001
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.001	0.999	0.000
S52.10 Fracture of upper end of radius (closed)	0.001	0.999	0.000
S52.71 Multiple fractures of forearm (open)	0.001	0.999	0.000
E05.5 Thyroid crisis or storm	0.001	0.999	0.001
E05.4 Thyrotoxicosis factitia	0.001	0.999	0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.001	0.999	0.001
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.001	0.999	0.001
K55.2 Angiodysplasia of colon	0.001	0.999	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.001	0.999	0.000
S92.5 Fracture of other toe	0.001	0.999	0.000
C60-C63 Malignant neoplasms of male genital organs	0.000	0.999	0.001
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.001	0.999	0.000
S62.70 Multiple fractures of fingers (closed)	0.001	0.999	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.001	0.999	0.000
I21 Acute myocardial infarction	0.001	0.999	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.001	0.999	0.000
O31 Complications specific to multiple gestation	0.001	0.999	0.000
C71.1 Frontal lobe	0.001	0.999	0.000
C81.9 Hodgkin's disease, unspecified	0.001	0.999	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.999	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.999	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.999	0.000
E34.5 Androgen resistance syndrome	0.001	0.999	0.000
E34.4 Constitutional tall stature	0.001	0.999	0.000
E34.3 Short stature, not elsewhere classified	0.001	0.999	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.999	0.000
E34.1 Other hypersecretion of intestinal hormones	0.001	0.999	0.000
R30.9 Painful micturition, unspecified	0.001	0.999	0.000
S52.70 Multiple fractures of forearm (closed)	0.001	0.999	0.000
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
O36.9 Maternal care for foetal problem, unspecified	0.001	0.999	0.000
O90.5 Postpartum thyroiditis	0.001	0.999	0.000
O90.4 Postpartum acute renal failure	0.001	0.999	0.000
O90.3 Cardiomyopathy in the puerperium	0.001	0.999	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.001	0.999	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.001	0.999	0.000
O36.2 Maternal care for hydrops foetalis	0.001	0.999	0.000
Y57.8 Other drugs and medicaments	0.001	0.999	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.001	0.999	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.000	0.999	0.001
E05.8 Other thyrotoxicosis	0.001	0.999	0.001
G96.0 Cerebrospinal fluid leak	0.001	0.999	0.000
S61.7 Multiple open wounds of wrist and hand	0.001	0.999	0.000
S92.30 Fracture of metatarsal bone (closed)	0.001	0.999	0.000
O41 Other disorders of amniotic fluid and membranes	0.001	0.999	0.000
D22.9 Melanocytic naevi, unspecified	0.001	0.999	0.000
E06.9 Thyroiditis, unspecified	0.001	0.999	0.000
I21.9 Acute myocardial infarction, unspecified	0.001	0.999	0.000
K86.8 Other specified diseases of pancreas	0.001	0.999	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.001	0.999	0.000
O45 Premature separation of placenta [abruptio placentae]	0.001	0.999	0.000
C81.1 Nodular sclerosis	0.001	0.999	0.000
Y57 Other and unspecified drugs and medicaments	0.001	0.999	0.000
D03.5 Melanoma in situ of trunk	0.000	0.999	0.001
D03.4 Melanoma in situ of scalp and neck	0.000	0.999	0.001
D41.0 Kidney	0.001	0.999	0.000
O41.0 Oligohydramnios	0.001	0.999	0.000
O90.9 Complication of the puerperium, unspecified	0.001	0.999	0.000
T51.9 Alcohol, unspecified	0.000	0.999	0.001
X49.9 Unspecified place	0.000	0.999	0.001
C63 Malignant neoplasm of other and unspecified male genital organs	0.000	0.999	0.001
D69.0 Allergic purpura	0.001	0.999	0.000
H27.8 Other specified disorders of lens	0.000	0.999	0.001
I21.X Presumed acute myicardial infaction (unconfirmed)	0.001	0.999	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.999	0.001
M71.2 Synovial cyst of popliteal space [Baker]	0.000	0.999	0.001
O31.8 Other complications specific to multiple gestation	0.001	0.999	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.001	0.999	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.001	0.999	0.000
O31.0 Papyraceous foetus	0.001	0.999	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.001	0.999	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.001	0.999	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.001	0.999	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.001	0.999	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.001	0.999	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.001	0.999	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.001	0.999	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.001	0.999	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.001	0.999	0.000
S92.3 Fracture of metatarsal bone	0.001	0.999	0.000
D03 Melanoma in situ	0.000	0.999	0.001
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
E04.9 Non-toxic goitre, unspecified	0.001	0.999	0.000
H44.2 Degenerative myopia	0.000	0.999	0.001
O75.0 Maternal distress during labour and delivery	0.001	0.999	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.001	0.999	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.999	0.001
B00.9 Herpesviral infection, unspecified	0.001	0.999	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.001	0.999	0.000
O90.1 Disruption of perineal obstetric wound	0.001	0.999	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.001	0.999	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.001	0.999	0.000
O41.1 Infection of amniotic sac and membranes	0.001	0.999	0.000
O46.9 Antepartum haemorrhage, unspecified	0.001	0.999	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.999	0.001
C62 Malignant neoplasm of testis	0.000	0.999	0.001
S92 Fracture of foot, except ankle	0.001	0.999	0.000
D37.5 Rectum	0.001	0.999	0.000
E06.3 Autoimmune thyroiditis	0.001	0.999	0.000
E34.8 Other specified endocrine disorders	0.001	0.999	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.999	0.001
J35.0 Chronic tonsillitis	0.000	0.999	0.001
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.001	0.999	0.000
O82.1 Delivery by emergency Caesarean section	0.001	0.999	0.000
S61 Open wound of wrist and hand	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.001	0.999	0.000
I78.1 Naevus, nonneoplastic	0.001	0.999	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.001	0.999	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.001	0.999	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.001	0.999	0.000
O45.8 Other premature separation of placenta	0.001	0.999	0.000
O45.0 Premature separation of placenta with coagulation defect	0.001	0.999	0.000
Y57.7 Vitamins, not elsewhere classified	0.001	0.999	0.000
Y57.6 Other diagnostic agents	0.001	0.999	0.000
Y57.4 Pharmaceutical excipients	0.001	0.999	0.000
Y57.3 Alcohol deterrents	0.001	0.999	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.001	0.999	0.000
Y57.1 Lipotropic drugs	0.001	0.999	0.000
Y57.0 Appetite depressants [anorectics]	0.001	0.999	0.000
C69 Malignant neoplasm of eye and adnexa	0.001	0.999	0.000
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec	0.000	0.999	0.001
M71.28 Synovial cyst of popliteal space [Baker]-Other	0.000	0.999	0.001
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot	0.000	0.999	0.001
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh	0.000	0.999	0.001
M71.24 Synovial cyst of popliteal space [Baker]-Hand	0.000	0.999	0.001
M71.23 Synovial cyst of popliteal space [Baker]-Forearm	0.000	0.999	0.001
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm	0.000	0.999	0.001
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region	0.000	0.999	0.001
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites	0.000	0.999	0.001
S92.31 Fracture of metatarsal bone (open)	0.001	0.999	0.000
C63.9 Male genital organ, unspecified	0.000	0.999	0.001
C63.8 Overlapping lesion of male genital organs	0.000	0.999	0.001
C63.7 Other specified male genital organs	0.000	0.999	0.001
C63.2 Scrotum	0.000	0.999	0.001
C63.1 Spermatic cord	0.000	0.999	0.001
C63.0 Epididymis	0.000	0.999	0.001
G50.0 Trigeminal neuralgia	0.000	0.999	0.001
O32.8 Maternal care for other malpresentation of foetus	0.001	0.999	0.000
O75.8 Other specified complications of labour and delivery	0.001	0.999	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.001	0.999	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.001	0.999	0.000
C02.4 Lingual tonsil	0.001	0.999	0.000
C15.9 Oesophagus, unspecified	0.001	0.999	0.000
D03.9 Melanoma in situ, unspecified	0.000	0.999	0.001
D03.8 Melanoma in situ of other sites	0.000	0.999	0.001
D03.1 Melanoma in situ of eyelid, including canthus	0.000	0.999	0.001
D03.0 Melanoma in situ of lip	0.000	0.999	0.001
D47.2 Monoclonal gammopathy	0.001	0.999	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.001	0.999	0.000
C60 Malignant neoplasm of penis	0.000	0.999	0.001
Z41 Procedures for purposes other than remedying health state	0.000	0.999	0.001
S52.20 Fracture of shaft of ulna (closed)	0.001	0.999	0.000
C62.0 Undescended testis	0.000	0.999	0.001
C69.0 Conjunctiva	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations