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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2251396
log Bayes Factor = 222.188
Chromosome 6   position 31,364,707  (GRCh37) Explore rs2251396 on Ensembl!
Variant rs2251396 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
E14.9 Without complications
0.999 0.001 0.000
J33.0 Polyp of nasal cavity
0.998 0.002 0.000
E27 Other disorders of adrenal gland
0.998 0.002 0.000
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
E27.1 Primary adrenocortical insufficiency
0.998 0.002 0.000
E16.2 Hypoglycaemia, unspecified
0.998 0.002 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.998 0.002 0.000
H36 Retinal disorders in diseases classified elsewhere
0.998 0.002 0.000
K90 Intestinal malabsorption
0.998 0.002 0.000
H30-H36 Disorders of choroid and retina
0.997 0.003 0.000
J33 Nasal polyp
0.996 0.004 0.000
M05 Seropositive rheumatoid arthritis
0.995 0.005 0.000
E83.1 Disorders of iron metabolism
0.000 0.006 0.994
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.993 0.007 0.000
J33.9 Nasal polyp, unspecified
0.993 0.007 0.000
E11 Non-insulin-dependent diabetes mellitus
0.992 0.008 0.000
E10.4 With neurological complications
0.992 0.008 0.000
E14.3 With ophthalmic complications
0.991 0.009 0.000
I73.0 Raynaud's syndrome
0.991 0.009 0.000
I73 Other peripheral vascular diseases
0.990 0.010 0.000
K75 Other inflammatory liver diseases
0.990 0.010 0.000
K70-K77 Diseases of liver
0.989 0.011 0.000
K75.4 Autoimmune hepatitis
0.989 0.011 0.000
Chapter XI Diseases of the digestive system
0.989 0.011 0.000
K90-K93 Other diseases of the digestive system
0.989 0.011 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.988 0.012 0.000
M35 Other systemic involvement of connective tissue
0.988 0.012 0.000
M35.0 Sicca syndrome [Sjogren]
0.987 0.013 0.000
D50-D53 Nutritional anaemias
0.986 0.014 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.015 0.985
I70-I79 Diseases of arteries, arterioles and capillaries
0.982 0.018 0.000
M20-M25 Other joint disorders
0.982 0.018 0.000
Chapter I Certain infectious and parasitic diseases
0.982 0.018 0.000
D50 Iron deficiency anaemia
0.981 0.019 0.000
E10.2 With renal complications
0.980 0.020 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.973 0.027 0.000
E10.0 With coma
0.972 0.028 0.000
B25-B34 Other viral diseases
0.970 0.030 0.000
Chapter VII Diseases of the eye and adnexa
0.970 0.030 0.000
D50.9 Iron deficiency anaemia, unspecified
0.970 0.030 0.000
K73 Chronic hepatitis, not elsewhere classified
0.969 0.031 0.000
B35-B49 Mycoses
0.967 0.033 0.000
K75.8 Other specified inflammatory liver diseases
0.964 0.036 0.000
I73.9 Peripheral vascular disease, unspecified
0.961 0.039 0.000
E11.1 With ketoacidosis
0.961 0.039 0.000
E11.3 With ophthalmic complications
0.960 0.040 0.000
L40.0 Psoriasis vulgaris
0.000 0.043 0.957
H34 Retinal vascular occlusions
0.953 0.047 0.000
B34 Viral infection of unspecified site
0.949 0.051 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.947 0.053 0.000
I77 Other disorders of arteries and arterioles
0.940 0.060 0.000
D50.8 Other iron deficiency anaemias
0.938 0.062 0.000
M35.3 Polymyalgia rheumatica
0.934 0.066 0.000
B37 Candidiasis
0.934 0.066 0.000
B34.9 Viral infection, unspecified
0.933 0.067 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.933 0.067 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.932 0.068 0.000
D62 Acute posthaemorrhagic anaemia
0.932 0.068 0.000
M34 Systemic sclerosis
0.930 0.070 0.000
J45 Asthma
0.926 0.074 0.000
B37.9 Candidiasis, unspecified
0.925 0.075 0.000
I71 Aortic aneurysm and dissection
0.924 0.076 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.924 0.076 0.000
M32 Systemic lupus erythematosus
0.921 0.079 0.000
M10 Gout
0.921 0.079 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.920 0.080 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.919 0.081 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.916 0.084 0.000
M35.1 Other overlap syndromes
0.905 0.095 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.903 0.097 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.901 0.099 0.000
I77.1 Stricture of artery
0.897 0.103 0.000
K90.9 Intestinal malabsorption, unspecified
0.893 0.107 0.000
K73.9 Chronic hepatitis, unspecified
0.888 0.112 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.881 0.119 0.000
M45 Ankylosing spondylitis
0.007 0.120 0.873
M06.3 Rheumatoid nodule
0.874 0.126 0.000
I77.6 Arteritis, unspecified
0.873 0.127 0.000
E22 Hyperfunction of pituitary gland
0.871 0.129 0.000
E14.8 With unspecified complications
0.871 0.129 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.869 0.131 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.866 0.134 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.865 0.135 0.000
Chapter X Diseases of the respiratory system
0.864 0.136 0.000
B25 Cytomegaloviral disease
0.863 0.137 0.000
J40-J47 Chronic lower respiratory diseases
0.862 0.138 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.861 0.139 0.000
H34.2 Other retinal artery occlusions
0.859 0.141 0.000
D69 Purpura and other haemorrhagic conditions
0.859 0.141 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.858 0.142 0.000
B35 Dermatophytosis
0.857 0.143 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.857 0.143 0.000
H33 Retinal detachments and breaks
0.856 0.144 0.000
H30 Chorioretinal inflammation
0.856 0.144 0.000
E14.6 With other specified complications
0.852 0.148 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.002 0.154 0.845
D80-D89 Certain disorders involving the immune mechanism
0.842 0.158 0.000
E23 Hypofunction and other disorders of pituitary gland
0.840 0.160 0.000
J33.1 Polypoid sinus degeneration
0.839 0.161 0.000
E11.0 With coma
0.838 0.162 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.837 0.162 0.000
M05.8 Other seropositive rheumatoid arthritis
0.835 0.165 0.000
E10.6 With other specified complications
0.835 0.165 0.000
K90.8 Other intestinal malabsorption
0.834 0.166 0.000
E14.2 Withrenal complications
0.834 0.166 0.000
B44 Aspergillosis
0.833 0.167 0.000
E11.5 With peripheral circulatory complications
0.832 0.168 0.000
E10.8 With unspecified complications
0.830 0.170 0.000
E10.5 With peripheral circulatory complications
0.830 0.170 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.830 0.170 0.000
H43-H45 Disorders of vitreous body and globe
0.828 0.172 0.000
H33.3 Retinal breaks without detachment
0.827 0.173 0.000
E28 Ovarian dysfunction
0.826 0.174 0.000
M86-M90 Other osteopathies
0.824 0.176 0.000
D61 Other aplastic anaemias
0.823 0.177 0.000
E14.1 With ketoacidosis
0.821 0.179 0.000
H34.8 Other retinal vascular occlusions
0.820 0.180 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.818 0.182 0.000
A15-A19 Tuberculosis
0.818 0.182 0.000
M34.9 Systemic sclerosis, unspecified
0.814 0.186 0.000
E20 Hypoparathyroidism
0.814 0.186 0.000
A63.0 Anogenital (venereal) warts
0.809 0.191 0.000
E50-E64 Other nutritional deficiencies
0.808 0.192 0.000
M10.9 Gout, unspecified
0.804 0.196 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.802 0.198 0.000
E10.7 With multiple complications
0.800 0.200 0.000
M10.0 Idiopathic gout
0.795 0.205 0.000
E23.2 Diabetes insipidus
0.795 0.205 0.000
E11.7 With multiple complications
0.793 0.207 0.000
H31 Other disorders of choroid
0.792 0.208 0.000
Chapter VIII Diseases of the ear and mastoid process
0.792 0.208 0.000
M12 Other specific arthropathies
0.789 0.211 0.000
K77 Liver disorders in diseases classified elsewhere
0.788 0.212 0.000
B33 Other viral diseases, not elsewhere classified
0.783 0.217 0.000
D69.0 Allergic purpura
0.781 0.219 0.000
H43 Disorders of vitreous body
0.781 0.219 0.000
M10.94 Gout, unspecified (Hand)
0.781 0.219 0.000
B35.1 Tinea unguium
0.780 0.220 0.000
M34.1 CR(E)ST syndrome
0.780 0.220 0.000
M14 Arthropathies in other diseases classified elsewhere
0.779 0.220 0.000
Chapter IX Diseases of the circulatory system
0.779 0.221 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.779 0.221 0.000
H34.1 Central retinal artery occlusion
0.778 0.222 0.000
E31 Polyglandular dysfunction
0.778 0.222 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.774 0.226 0.000
J30-J39 Other diseases of upper respiratory tract
0.773 0.227 0.000
D50.1 Sideropenic dysphagia
0.772 0.228 0.000
H43.1 Vitreous haemorrhage
0.770 0.230 0.000
B25.9 Cytomegaloviral disease, unspecified
0.767 0.233 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.766 0.234 0.000
J33.8 Other polyp of sinus
0.766 0.234 0.000
E06 Thyroiditis
0.765 0.235 0.000
L40.8 Other psoriasis
0.000 0.238 0.762
I73.1 Thromboangiitis obliterans [Buerger]
0.759 0.241 0.000
M86 Osteomyelitis
0.759 0.241 0.000
L40.1 Generalised pustular psoriasis
0.000 0.242 0.758
M06.98 Rheumatoid arthritis, unspecified (Other)
0.757 0.242 0.000
B34.4 Papovirus infection, unspecified
0.757 0.243 0.000
E40-E46 Malnutrition
0.757 0.243 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.755 0.245 0.000
M65-M68 Disorders of synovium and tendon
0.752 0.248 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.751 0.249 0.000
D55-D59 Haemolytic anaemias
0.750 0.249 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.750 0.250 0.000
M34.8 Other forms of systemic sclerosis
0.750 0.250 0.000
E14.5 With peripheral circulatory complications
0.750 0.250 0.000
I74 Arterial embolism and thrombosis
0.746 0.254 0.000
J45.1 Nonallergic asthma
0.746 0.254 0.000
M06.34 Rheumatoid nodule (Hand)
0.744 0.256 0.000
H33.1 Retinoschisis and retinal cysts
0.743 0.257 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.742 0.258 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.740 0.260 0.000
H30.9 Chorioretinal inflammation, unspecified
0.740 0.260 0.000
E28.3 Primary ovarian failure
0.740 0.260 0.000
B37.4 Candidiasis of other urogenital sites
0.737 0.263 0.000
E16.1 Other hypoglycaemia
0.736 0.264 0.000
H60-H62 Diseases of external ear
0.733 0.267 0.000
J45.8 Mixed asthma
0.733 0.267 0.000
D69.6 Thrombocytopenia, unspecified
0.731 0.269 0.000
M06.4 Inflammatory polyarthropathy
0.729 0.271 0.000
I70 Atherosclerosis
0.729 0.271 0.000
E25 Adrenogenital disorders
0.723 0.277 0.000
E53 Deficiency of other B group vitamins
0.723 0.277 0.000
A52 Late syphilis
0.722 0.278 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.722 0.278 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.721 0.279 0.000
M08 Juvenile arthritis
0.718 0.282 0.000
J85 Abscess of lung and mediastinum
0.718 0.282 0.000
M10.96 Gout, unspecified (Lower leg)
0.718 0.282 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
B44.1 Other pulmonary aspergillosis
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.716 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.716 0.283 0.000
E32 Diseases of thymus
0.716 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.716 0.283 0.000
M32.8 Other forms of systemic lupus erythematosus
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.284 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.284 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.284 0.000
E16.3 Increased secretion of glucagon
0.716 0.284 0.000
M34.0 Progressive systemic sclerosis
0.716 0.284 0.000
E27.5 Adrenomedullary hyperfunction
0.716 0.284 0.000
E27.0 Other adrenocortical overactivity
0.716 0.284 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.715 0.285 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.715 0.285 0.000
K90.3 Pancreatic steatorrhoea
0.715 0.285 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.715 0.285 0.000
K90.1 Tropical sprue
0.715 0.285 0.000
R31 Unspecified haematuria
0.000 0.285 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.714 0.285 0.000
I77.2 Rupture of artery
0.714 0.286 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.713 0.287 0.000
M05.2 Rheumatoid vasculitis
0.713 0.287 0.000
M05.1 Rheumatoid lung disease
0.713 0.287 0.000
M05.0 Felty's syndrome
0.713 0.287 0.000
D69.4 Other primary thrombocytopenia
0.712 0.288 0.000
E24 Cushing's syndrome
0.711 0.289 0.000
K75.2 Nonspecific reactive hepatitis
0.710 0.290 0.000
K75.1 Phlebitis of portal vein
0.710 0.290 0.000
K72 Hepatic failure, not elsewhere classified
0.710 0.290 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.709 0.291 0.000
B37.8 Candidiasis of other sites
0.709 0.291 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.708 0.292 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.708 0.292 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.708 0.292 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.708 0.292 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.708 0.292 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.708 0.292 0.000
M35.5 Multifocal fibrosclerosis
0.708 0.292 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.708 0.292 0.000
H61 Other disorders of external ear
0.704 0.296 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.704 0.296 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.704 0.296 0.000
A75-A79 Rickettsioses
0.704 0.296 0.000
A70-A74 Other diseases caused by chlamydiae
0.704 0.296 0.000
A20-A28 Certain zoonotic bacterial diseases
0.704 0.296 0.000
D69.2 Other nonthrombocytopenic purpura
0.702 0.298 0.000
E03.8 Other specified hypothyroidism
0.702 0.298 0.000
E07 Other disorders of thyroid
0.701 0.299 0.000
K71 Toxic liver disease
0.700 0.300 0.000
M06.8 Other specified rheumatoid arthritis
0.697 0.303 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.697 0.303 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.697 0.303 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.696 0.304 0.000
B30 Viral conjunctivitis
0.696 0.304 0.000
B26 Mumps
0.696 0.304 0.000
E13 Other specified diabetes mellitus
0.695 0.305 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.694 0.305 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.694 0.305 0.000
B48 Other mycoses, not elsewhere classified
0.693 0.307 0.000
B47 Mycetoma
0.693 0.307 0.000
B46 Zygomycosis
0.693 0.307 0.000
B45 Cryptococcosis
0.693 0.307 0.000
B43 Chromomycosis and phaeomycotic abscess
0.693 0.307 0.000
B42 Sporotrichosis
0.693 0.307 0.000
B41 Paracoccidioidomycosis
0.693 0.307 0.000
B40 Blastomycosis
0.693 0.307 0.000
B39 Histoplasmosis
0.693 0.307 0.000
B38 Coccidioidomycosis
0.693 0.307 0.000
D69.8 Other specified haemorrhagic conditions
0.691 0.309 0.000
H33.4 Traction detachment of retina
0.689 0.311 0.000
E11.8 With unspecified complications
0.688 0.312 0.000
D60.9 Acquired pure red cell aplasia, unspecified
0.687 0.313 0.000
M35.7 Hypermobility syndrome
0.687 0.313 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.686 0.314 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.686 0.314 0.000
M88 Paget's disease of bone [osteitis deformans]
0.685 0.315 0.000
M80-M85 Disorders of bone density and structure
0.685 0.315 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.684 0.316 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.684 0.316 0.000
H34.0 Transient retinal artery occlusion
0.683 0.317 0.000
D69.5 Secondary thrombocytopenia
0.683 0.317 0.000
E20.9 Hypoparathyroidism, unspecified
0.681 0.319 0.000
D61.1 Drug-induced aplastic anaemia
0.681 0.319 0.000
B34.3 Parvovirus infection, unspecified
0.680 0.320 0.000
B34.2 Coronavirus infection, unspecified
0.680 0.320 0.000
B34.1 Enterovirus infection, unspecified
0.680 0.320 0.000
B34.0 Adenovirus infection, unspecified
0.680 0.320 0.000
B37.1 Pulmonary candidiasis
0.678 0.322 0.000
B36 Other superficial mycoses
0.677 0.323 0.000
D53 Other nutritional anaemias
0.676 0.324 0.000
E11.9 Without complications
0.675 0.325 0.000
A60 Anogenital herpesviral [herpes simplex] infections
0.675 0.325 0.000
B15-B19 Viral hepatitis
0.675 0.325 0.000
E22.1 Hyperprolactinaemia
0.675 0.325 0.000
D64.8 Other specified anaemias
0.674 0.326 0.000
I77.5 Necrosis of artery
0.674 0.326 0.000
I77.4 Coeliac artery compression syndrome
0.674 0.326 0.000
I77.3 Arterial fibromuscular dysplasia
0.674 0.326 0.000
M11 Other crystal arthropathies
0.674 0.326 0.000
C91 Lymphoid leukaemia
0.672 0.328 0.000
M30 Polyarteritis nodosa and related conditions
0.671 0.329 0.000
H34.9 Retinal vascular occlusion, unspecified
0.670 0.330 0.000
M86.9 Osteomyelitis, unspecified
0.670 0.330 0.000
B37.6 Candidal endocarditis
0.669 0.330 0.000
B37.5 Candidal meningitis
0.669 0.330 0.000
I79.1 Aortitis in diseases classified elsewhere
0.669 0.331 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.669 0.331 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.669 0.331 0.000
H35 Other retinal disorders
0.668 0.332 0.000
E05.8 Other thyrotoxicosis
0.668 0.332 0.000
H31.1 Choroidal degeneration
0.668 0.332 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.667 0.333 0.000
B35.6 Tinea cruris
0.665 0.335 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.665 0.335 0.000
D61.9 Aplastic anaemia, unspecified
0.665 0.335 0.000
I74.8 Embolism and thrombosis of other arteries
0.664 0.336 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.663 0.337 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.663 0.337 0.000
E27.2 Addisonian crisis
0.663 0.337 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.663 0.337 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.663 0.337 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.663 0.337 0.000
E53.8 Deficiency of other specified B group vitamins
0.663 0.337 0.000
D84 Other immunodeficiencies
0.662 0.338 0.000
I77.0 Arteriovenous fistula, acquired
0.661 0.339 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.660 0.340 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.660 0.340 0.000
M10.4 Other secondary gout
0.660 0.340 0.000
M10.3 Gout due to impairment of renal function
0.660 0.340 0.000
M10.2 Drug-induced gout
0.660 0.340 0.000
M10.1 Lead-induced gout
0.660 0.340 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.660 0.340 0.000
A59 Trichomoniasis
0.659 0.341 0.000
A56 Other sexually transmitted chlamydial diseases
0.659 0.341 0.000
A54 Gonococcal infection
0.659 0.341 0.000
A53 Other and unspecified syphilis
0.659 0.341 0.000
A51 Early syphilis
0.659 0.341 0.000
A50 Congenital syphilis
0.659 0.341 0.000
A64 Unspecified sexually transmitted disease
0.659 0.341 0.000
A58 Granuloma inguinale
0.659 0.341 0.000
A57 Chancroid
0.659 0.341 0.000
A55 Chlamydial lymphogranuloma (venereum)
0.659 0.341 0.000
E23.6 Other disorders of pituitary gland
0.658 0.342 0.000
K74 Fibrosis and cirrhosis of liver
0.658 0.342 0.000
M35.2 Behcet's disease
0.656 0.344 0.000
D86 Sarcoidosis
0.655 0.345 0.000
C91.1 Chronic lymphocytic leukaemia
0.654 0.346 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.005 0.346 0.649
H35.8 Other specified retinal disorders
0.653 0.347 0.000
E06.3 Autoimmune thyroiditis
0.653 0.347 0.000
D52 Folate deficiency anaemia
0.652 0.348 0.000
C85.1 B-cell lymphoma, unspecified
0.652 0.348 0.000
B25.8 Other cytomegaloviral diseases
0.651 0.349 0.000
Chapter II Neoplasms
0.650 0.350 0.000
M66 Spontaneous rupture of synovium and tendon
0.646 0.354 0.000
H30.2 Posterior cyclitis
0.646 0.354 0.000
B33.2 Viral carditis
0.645 0.354 0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.644 0.356 0.000
B37.7 Candidal septicaemia
0.643 0.357 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.642 0.358 0.000
M35.8 Other specified systemic involvement of connective tissue
0.642 0.358 0.000
B25.0 Cytomegaloviral pneumonitis
0.641 0.358 0.000
J85.2 Abscess of lung without pneumonia
0.641 0.359 0.000
M12.5 Traumatic arthropathy
0.641 0.359 0.000
B44.9 Aspergillosis, unspecified
0.640 0.360 0.000
A65-A69 Other spirochaetal diseases
0.639 0.361 0.000
A18 Tuberculosis of other organs
0.637 0.363 0.000
D80 Immunodeficiency with predominantly antibody defects
0.634 0.366 0.000
D83 Common variable immunodeficiency
0.633 0.367 0.000
B37.2 Candidiasis of skin and nail
0.633 0.367 0.000
E11.6 With other specified complications
0.632 0.368 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.005 0.369 0.626
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.005 0.369 0.626
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.005 0.369 0.626
M45.X4 Ankylosing spondylitis (Thoracic region)
0.005 0.369 0.626
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.005 0.369 0.626
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.005 0.369 0.626
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed
0.631 0.369 0.000
A63.8 Other specified predominantly sexually transmitted diseases
0.631 0.369 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.630 0.370 0.000
E27.9 Disorder of adrenal gland, unspecified
0.630 0.370 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.628 0.371 0.000
C15-C26 Malignant neoplasms of digestive organs
0.628 0.372 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.627 0.373 0.000
M06.38 Rheumatoid nodule (Other)
0.627 0.373 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.627 0.373 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.627 0.373 0.000
M06.33 Rheumatoid nodule (Forearm)
0.627 0.373 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.627 0.373 0.000
J46 Status asthmaticus
0.627 0.373 0.000
M10.04 Idiopathic gout (Hand)
0.626 0.374 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.626 0.374 0.000
E29 Testicular dysfunction
0.626 0.374 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.624 0.375 0.000
E22.8 Other hyperfunction of pituitary gland
0.624 0.375 0.000
D67 Hereditary factor IX deficiency
0.623 0.377 0.000
E51 Thiamine deficiency
0.623 0.377 0.000
H61.8 Other specified disorders of external ear
0.623 0.377 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.622 0.378 0.000
J41 Simple and mucopurulent chronic bronchitis
0.620 0.379 0.000
M31 Other necrotising vasculopathies
0.620 0.380 0.000
E14.4 With neurological complications
0.619 0.380 0.000
B25.2 Cytomegaloviral pancreatitis
0.619 0.381 0.000
B25.1 Cytomegaloviral hepatitis
0.619 0.381 0.000
D59 Acquired haemolytic anaemia
0.619 0.381 0.000
E31.0 Autoimmune polyglandular failure
0.619 0.381 0.000
J43 Emphysema
0.619 0.381 0.000
M67 Other disorders of synovium and tendon
0.618 0.382 0.000
C16 Malignant neoplasm of stomach
0.617 0.383 0.000
D69.1 Qualitative platelet defects
0.616 0.384 0.000
M86.1 Other acute osteomyelitis
0.616 0.384 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.616 0.384 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.615 0.385 0.000
H61.3 Acquired stenosis of external ear canal
0.615 0.385 0.000
B65-B83 Helminthiases
0.615 0.385 0.000
J85.1 Abscess of lung with pneumonia
0.615 0.385 0.000
B35.9 Dermatophytosis, unspecified
0.615 0.385 0.000
B35.8 Other dermatophytoses
0.615 0.385 0.000
B35.5 Tinea imbricata
0.615 0.385 0.000
B35.4 Tinea corporis
0.615 0.385 0.000
B35.2 Tinea manuum
0.615 0.385 0.000
B35.0 Tinea barbae and tinea capitis
0.615 0.385 0.000
H30.8 Other chorioretinal inflammations
0.614 0.386 0.000
H30.1 Disseminated chorioretinal inflammation
0.614 0.386 0.000
H30.0 Focal chorioretinal inflammation
0.614 0.386 0.000
M33 Dermatopolymyositis
0.612 0.388 0.000
M14.2 Diabetic arthropathy
0.610 0.390 0.000
H31.0 Chorioretinal scars
0.610 0.390 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.609 0.391 0.000
H61.0 Perichondritis of external ear
0.609 0.391 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.607 0.393 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.606 0.394 0.000
H35.2 Other proliferative retinopathy
0.606 0.394 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.605 0.395 0.000
L40-L45 Papulosquamous disorders
0.476 0.395 0.128
M10.00 Idiopathic gout (Multiple sites)
0.605 0.395 0.000
D81 Combined immunodeficiencies
0.604 0.396 0.000
D82 Immunodeficiency associated with other major defects
0.604 0.396 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.602 0.398 0.000
E23.1 Drug-induced hypopituitarism
0.602 0.398 0.000
D86.9 Sarcoidosis, unspecified
0.602 0.398 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.601 0.399 0.000
M60-M63 Disorders of muscles
0.600 0.400 0.000
E22.0 Acromegaly and pituitary gigantism
0.599 0.401 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.599 0.401 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.599 0.401 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.599 0.401 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.599 0.401 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.599 0.401 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.599 0.401 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.599 0.401 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.599 0.401 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.599 0.401 0.000
M10.02 Idiopathic gout (Upper arm)
0.598 0.402 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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