TreeWAS – Variant ID: rs2254287

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.002	0.998
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.009	0.991
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.015	0.985
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.039	0.961
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.075	0.925
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.079	0.921
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.104	0.896
E10 Insulin-dependent diabetes mellitus	0.115	0.885
E10.9 Without complications	0.120	0.880
E10.3 With ophthalmic complications	0.122	0.878
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.166	0.834
E10.1 With ketoacidosis	0.167	0.833
E03 Other hypothyroidism	0.169	0.831
M06 Other rheumatoid arthritis	0.195	0.805
M06.98 Rheumatoid arthritis, unspecified (Other)	0.210	0.790
E10.6 With other specified complications	0.227	0.773
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.236	0.764
M06.3 Rheumatoid nodule	0.249	0.751
E10.2 With renal complications	0.293	0.707
E10.0 With coma	0.299	0.701
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.326	0.674
E10.7 With multiple complications	0.334	0.666
E03.8 Other specified hypothyroidism	0.341	0.659
E00-E07 Disorders of thyroid gland	0.346	0.654
E10-E14 Diabetes mellitus	0.350	0.650
M06.34 Rheumatoid nodule (Hand)	0.351	0.649
E03.0 Congenital hypothyroidism with diffuse goitre	0.352	0.648
M06.37 Rheumatoid nodule (Ankle and foot)	0.354	0.645
E10.8 With unspecified complications	0.365	0.635
Chapter IV Endocrine, nutritional and metabolic diseases	0.369	0.631
M06.4 Inflammatory polyarthropathy	0.378	0.622
M06.30 Rheumatoid nodule (Multiple sites)	0.391	0.609
E03.5 Myxoedema coma	0.404	0.596
E03.4 Atrophy of thyroid (acquired)	0.404	0.596
E03.3 Postinfectious hypothyroidism	0.404	0.596
M06.8 Other specified rheumatoid arthritis	0.413	0.587
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.420	0.580
M06.2 Rheumatoid bursitis	0.422	0.577
E03.1 Congenital hypothyroidism without goitre	0.436	0.564
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.440	0.560
E10.4 With neurological complications	0.446	0.554
M06.1 Adult-onset Still's disease	0.446	0.553
M06.32 Rheumatoid nodule (Upper arm)	0.455	0.545
E05 Thyrotoxicosis [hyperthyroidism]	0.458	0.542
M06.39 Rheumatoid nodule (Site unspecified)	0.461	0.538
M06.38 Rheumatoid nodule (Other)	0.461	0.538
M06.36 Rheumatoid nodule (Lower leg)	0.461	0.538
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.461	0.538
M06.31 Rheumatoid nodule (Shoulder region)	0.461	0.538
J47 Bronchiectasis	0.462	0.538
E50-E64 Other nutritional deficiencies	0.477	0.523
E16 Other disorders of pancreatic internal secretion	0.490	0.510
M06.33 Rheumatoid nodule (Forearm)	0.501	0.498
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.512	0.488
E06 Thyroiditis	0.521	0.478
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.531	0.469
E00 Congenital iodine-deficiency syndrome	0.531	0.469
E12 Malnutrition-related diabetes mellitus	0.534	0.466
E16.2 Hypoglycaemia, unspecified	0.534	0.466
E10.5 With peripheral circulatory complications	0.536	0.464
E53 Deficiency of other B group vitamins	0.542	0.458
M06.0 Seronegative rheumatoid arthritis	0.542	0.458
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.550	0.450
M06.48 Inflammatory polyarthropathy (Other)	0.554	0.446
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.554	0.446
M06.46 Inflammatory polyarthropathy (Lower leg)	0.554	0.446
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.554	0.446
M06.44 Inflammatory polyarthropathy (Hand)	0.554	0.446
M06.43 Inflammatory polyarthropathy (Forearm)	0.554	0.446
M06.42 Inflammatory polyarthropathy (Upper arm)	0.554	0.446
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.554	0.446
E05.0 Thyrotoxicosis with diffuse goitre	0.555	0.445
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.570	0.430
E53.8 Deficiency of other specified B group vitamins	0.578	0.422
E58 Dietary calcium deficiency	0.579	0.421
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.579	0.421
M06.88 Other specified rheumatoid arthritis (Other)	0.579	0.421
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.579	0.421
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.579	0.421
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.579	0.421
M06.84 Other specified rheumatoid arthritis (Hand)	0.579	0.421
M06.83 Other specified rheumatoid arthritis (Forearm)	0.579	0.421
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.579	0.421
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.579	0.421
E05.9 Thyrotoxicosis, unspecified	0.582	0.418
M06.29 Rheumatoid bursitis (Site unspecified)	0.586	0.414
M06.28 Rheumatoid bursitis (Other)	0.586	0.414
M06.27 Rheumatoid bursitis (Ankle and foot)	0.586	0.414
M06.26 Rheumatoid bursitis (Lower leg)	0.586	0.414
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.586	0.414
M06.24 Rheumatoid bursitis (Hand)	0.586	0.414
M06.23 Rheumatoid bursitis (Forearm)	0.586	0.414
M06.22 Rheumatoid bursitis (Upper arm)	0.586	0.414
M06.21 Rheumatoid bursitis (Shoulder region)	0.586	0.414
M06.20 Rheumatoid bursitis (Multiple sites)	0.586	0.414
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.586	0.414
E16.0 Drug-induced hypoglycaemia without coma	0.592	0.408
E15 Nondiabetic hypoglycaemic coma	0.598	0.402
M06.19 Adult-onset Still's disease (Site unspecified)	0.603	0.397
M06.18 Adult-onset Still's disease (Other)	0.603	0.397
M06.17 Adult-onset Still's disease (Ankle and foot)	0.603	0.397
M06.16 Adult-onset Still's disease (Lower leg)	0.603	0.397
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.603	0.397
M06.14 Adult-onset Still's disease (Hand)	0.603	0.397
M06.13 Adult-onset Still's disease (Forearm)	0.603	0.397
M06.12 Adult-onset Still's disease (Upper arm)	0.603	0.397
M06.11 Adult-onset Still's disease (Shoulder region)	0.603	0.397
E05.5 Thyroid crisis or storm	0.611	0.388
E05.4 Thyrotoxicosis factitia	0.611	0.388
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.611	0.388
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.611	0.388
E06.3 Autoimmune thyroiditis	0.624	0.375
E64 Sequelae of malnutrition and other nutritional deficiencies	0.625	0.375
E63 Other nutritional deficiencies	0.625	0.375
E50 Vitamin A deficiency	0.625	0.375
E60 Dietary zinc deficiency	0.625	0.375
E59 Dietary selenium deficiency	0.625	0.375
E54 Ascorbic acid deficiency	0.625	0.375
E52 Niacin deficiency [pellagra]	0.625	0.375
M06.10 Adult-onset Still's disease (Multiple sites)	0.627	0.373
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.627	0.373
E55 Vitamin D deficiency	0.633	0.367
E16.9 Disorder of pancreatic internal secretion, unspecified	0.634	0.366
E16.8 Other specified disorders of pancreatic internal secretion	0.634	0.366
E16.4 Abnormal secretion of gastrin	0.634	0.366
E16.3 Increased secretion of glucagon	0.634	0.366
E51 Thiamine deficiency	0.634	0.365
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.637	0.363
M05-M14 Inflammatory polyarthropathies	0.637	0.363
E56 Other vitamin deficiencies	0.637	0.362
E40-E46 Malnutrition	0.638	0.361
E06.5 Other chronic thyroiditis	0.647	0.353
E05.8 Other thyrotoxicosis	0.647	0.353
E14 Unspecified diabetes mellitus	0.648	0.352
E13 Other specified diabetes mellitus	0.655	0.345
E16.1 Other hypoglycaemia	0.656	0.344
E06.4 Drug-induced thyroiditis	0.657	0.343
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.657	0.343
E06.0 Acute thyroiditis	0.657	0.343
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.663	0.336
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.663	0.336
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.663	0.336
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.663	0.336
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.663	0.336
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.663	0.336
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.663	0.336
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.663	0.336
E06.1 Subacute thyroiditis	0.664	0.336
E12.9 Without complications	0.666	0.334
E12.8 With unspecified complications	0.666	0.334
E12.7 With multiple complications	0.666	0.334
E12.6 With other specified complications	0.666	0.334
E12.5 With peripheral circulatory complications	0.666	0.334
E12.4 With neurological complications	0.666	0.334
E12.3 With ophthalmic complications	0.666	0.334
E12.2 With renal complications	0.666	0.334
E12.1 With ketoacidosis	0.666	0.334
E12.0 With coma	0.666	0.334
J40-J47 Chronic lower respiratory diseases	0.668	0.332
J43.9 Emphysema, unspecified	0.669	0.331
J43 Emphysema	0.671	0.329
E53.1 Pyridoxine deficiency	0.671	0.329
E53.0 Riboflavin deficiency	0.671	0.329
M06.08 Seronegative rheumatoid arthritis (Other)	0.672	0.328
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.672	0.328
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.672	0.328
E02 Subclinical iodine-deficiency hypothyroidism	0.673	0.327
E61 Deficiency of other nutrient elements	0.682	0.318
E06.9 Thyroiditis, unspecified	0.692	0.308
J44 Other chronic obstructive pulmonary disease	0.692	0.308
M07 Psoriatic and enteropathic arthropathies	0.693	0.307
M05 Seropositive rheumatoid arthritis	0.696	0.304
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.699	0.301
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.700	0.300
M06.04 Seronegative rheumatoid arthritis (Hand)	0.702	0.298
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.706	0.294
E53.9 Vitamin B deficiency, unspecified	0.708	0.292
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.715	0.285
E14.2 Withrenal complications	0.720	0.280
M10 Gout	0.722	0.278
E14.6 With other specified complications	0.726	0.274
M12 Other specific arthropathies	0.729	0.270
E50.9 Vitamin A deficiency, unspecified	0.731	0.269
E50.8 Other manifestations of vitamin A deficiency	0.731	0.269
E50.7 Other ocular manifestations of vitamin A deficiency	0.731	0.269
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.731	0.269
E50.5 Vitamin A deficiency with night blindness	0.731	0.269
E50.4 Vitamin A deficiency with keratomalacia	0.731	0.269
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.731	0.269
E50.2 Vitamin A deficiency with corneal xerosis	0.731	0.269
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.731	0.269
E50.0 Vitamin A deficiency with conjunctival xerosis	0.731	0.269
E63.9 Nutritional deficiency, unspecified	0.731	0.269
E63.8 Other specified nutritional deficiencies	0.731	0.269
E63.1 Imbalance of constituents of food intake	0.731	0.269
E63.0 Essential fatty acid [EFA] deficiency	0.731	0.269
E64.9 Sequelae of unspecified nutritional deficiency	0.731	0.269
E64.8 Sequelae of other nutritional deficiencies	0.731	0.269
E64.3 Sequelae of rickets	0.731	0.269
E64.2 Sequelae of vitamin C deficiency	0.731	0.269
E64.1 Sequelae of vitamin A deficiency	0.731	0.269
E64.0 Sequelae of protein-energy malnutrition	0.731	0.269
M07.3 Other psoriatic arthropathies	0.733	0.267
E55.0 Rickets, active	0.736	0.264
E04 Other non-toxic goitre	0.737	0.263
E51.9 Thiamine deficiency, unspecified	0.738	0.262
E51.8 Other manifestations of thiamine deficiency	0.738	0.262
E51.1 Beriberi	0.738	0.262
M09 Juvenile arthritis in diseases classified elsewhere	0.740	0.260
M08 Juvenile arthritis	0.740	0.260
E56.9 Vitamin deficiency, unspecified	0.740	0.260
E56.8 Deficiency of other vitamins	0.740	0.260
E56.0 Deficiency of vitamin E	0.740	0.260
E44 Protein-energy malnutrition of moderate and mild degree	0.741	0.259
E45 Retarded development following protein-energy malnutrition	0.741	0.259
E43 Unspecified severe protein-energy malnutrition	0.741	0.259
E42 Marasmic kwashiorkor	0.741	0.259
E41 Nutritional marasmus	0.741	0.259
E40 Kwashiorkor	0.741	0.259
E14.8 With unspecified complications	0.742	0.258
E55.9 Vitamin D deficiency, unspecified	0.744	0.256
M05.9 Seropositive rheumatoid arthritis, unspecified	0.745	0.255
E51.2 Wernicke's encephalopathy	0.748	0.252
E14.7 With multiple complications	0.748	0.252
E14.0 With coma	0.748	0.252
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.749	0.251
E14.1 With ketoacidosis	0.750	0.250
E14.5 With peripheral circulatory complications	0.752	0.248
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.752	0.248
E13.8 With unspecified complications	0.753	0.247
E13.7 With multiple complications	0.753	0.247
E13.6 With other specified complications	0.753	0.247
E13.5 With peripheral circulatory complications	0.753	0.247
E13.4 With neurological complications	0.753	0.247
E13.2 With renal complications	0.753	0.247
E13.1 With ketoacidosis	0.753	0.247
E13.0 With coma	0.753	0.247
E56.1 Deficiency of vitamin K	0.753	0.247
M07.39 Other psoriatic arthropathies (Site unspecified)	0.757	0.243
J43.8 Other emphysema	0.759	0.241
E14.3 With ophthalmic complications	0.759	0.241
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.760	0.240
E65-E68 Obesity and other hyperalimentation	0.761	0.239
M14 Arthropathies in other diseases classified elsewhere	0.762	0.238
J43.1 Panlobular emphysema	0.764	0.236
J43.0 MacLeod's syndrome	0.764	0.236
M11 Other crystal arthropathies	0.768	0.232
E61.2 Magnesium deficiency	0.771	0.229
J44.9 Chronic obstructive pulmonary disease, unspecified	0.771	0.229
M05.8 Other seropositive rheumatoid arthritis	0.772	0.228
E61.9 Deficiency of nutrient element, unspecified	0.772	0.228
E61.8 Deficiency of other specified nutrient elements	0.772	0.228
E61.7 Deficiency of multiple nutrient elements	0.772	0.228
E61.6 Vanadium deficiency	0.772	0.228
E61.5 Molybdenum deficiency	0.772	0.228
E61.4 Chromium deficiency	0.772	0.228
E61.3 Manganese deficiency	0.772	0.228
E61.0 Copper deficiency	0.772	0.228
J41 Simple and mucopurulent chronic bronchitis	0.772	0.228
E13.3 With ophthalmic complications	0.773	0.226
E14.4 With neurological complications	0.777	0.223
M10.9 Gout, unspecified	0.779	0.221
M07.36 Other psoriatic arthropathies (Lower leg)	0.779	0.221
M05.2 Rheumatoid vasculitis	0.780	0.220
M07.6 Other enteropathic arthropathies	0.780	0.220
M07.5 Arthropathy in ulcerative colitis	0.780	0.220
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.780	0.220
M07.2 Psoriatic spondylitis	0.780	0.220
M07.1 Arthritis mutilans	0.780	0.220
M07.0 Distal interphalangeal psoriatic arthropathy	0.780	0.220
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.782	0.218
M05.1 Rheumatoid lung disease	0.782	0.218
M05.0 Felty's syndrome	0.782	0.218
E04.1 Non-toxic single thyroid nodule	0.784	0.216
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.789	0.211
M12.3 Palindromic rheumatism	0.790	0.210
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.791	0.209
E07 Other disorders of thyroid	0.794	0.205
M10.0 Idiopathic gout	0.797	0.203
J43.2 Centrilobular emphysema	0.800	0.200
M10.4 Other secondary gout	0.801	0.199
M10.2 Drug-induced gout	0.801	0.199
M10.1 Lead-induced gout	0.801	0.199
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.802	0.198
M10.97 Gout, unspecified (Ankle and foot)	0.802	0.198
M12.8 Other specific arthropathies, not elsewhere classified	0.806	0.194
M12.5 Traumatic arthropathy	0.806	0.194
M12.4 Intermittent hydrarthrosis	0.806	0.194
M12.1 Kaschin-Beck disease	0.806	0.194
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.806	0.194
M10.90 Gout, unspecified (Multiple sites)	0.806	0.194
M07.38 Other psoriatic arthropathies (Other)	0.809	0.191
M07.33 Other psoriatic arthropathies (Forearm)	0.809	0.191
M07.32 Other psoriatic arthropathies (Upper arm)	0.809	0.191
M07.31 Other psoriatic arthropathies (Shoulder region)	0.809	0.191
E04.8 Other specified non-toxic goitre	0.811	0.189
M10.3 Gout due to impairment of renal function	0.812	0.188
M12.2 Villonodular synovitis (pigmented)	0.812	0.187
M08.9 Juvenile arthritis, unspecified	0.813	0.187
M08.8 Other juvenile arthritis	0.813	0.187
M08.4 Pauciarticular juvenile arthritis	0.813	0.187
M08.3 Juvenile polyarthritis (seronegative)	0.813	0.187
M08.2 Juvenile arthritis with systemic onset	0.813	0.187
M08.1 Juvenile ankylosing spondylitis	0.813	0.187
M08.0 Juvenile rheumatoid arthritis	0.813	0.187
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.813	0.187
M09.2 Juvenile arthritis in ulcerative colitis	0.813	0.187
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.813	0.187
M09.0 Juvenile arthritis in psoriasis	0.813	0.187
E44.1 Mild protein-energy malnutrition	0.814	0.186
E44.0 Moderate protein-energy malnutrition	0.814	0.186
M10.94 Gout, unspecified (Hand)	0.816	0.184
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.817	0.183
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.817	0.183
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.817	0.183
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.824	0.176
M07.30 Other psoriatic arthropathies (Multiple sites)	0.825	0.175
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.826	0.174
M14.6 Neuropathic arthropathy	0.826	0.174
E67 Other hyperalimentation	0.829	0.171
E68 Sequelae of hyperalimentation	0.829	0.171
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.829	0.170
M14.4 Arthropathy in amyloidosis	0.829	0.170
M14.3 Lipoid dermatoarthritis	0.829	0.170
M14.1 Crystal arthropathy in other metabolic disorders	0.829	0.170
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.829	0.170
M14.2 Diabetic arthropathy	0.829	0.170
E04.0 Non-toxic diffuse goitre	0.830	0.170
E61.1 Iron deficiency	0.830	0.169
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.831	0.169
E46 Unspecified protein-energy malnutrition	0.832	0.168
M10.09 Idiopathic gout (Site unspecified)	0.832	0.167
M11.1 Familial chondrocalcinosis	0.834	0.166
M11.0 Hydroxyapatite deposition disease	0.834	0.166
E13.9 Without complications	0.835	0.164
M11.8 Other specified crystal arthropathies	0.836	0.164
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.836	0.164
M05.88 Other seropositive rheumatoid arthritis (Other)	0.836	0.164
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.836	0.164
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.836	0.164
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.836	0.164
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.836	0.164
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.836	0.164
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.836	0.164
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.836	0.164
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.836	0.163
J41.1 Mucopurulent chronic bronchitis	0.836	0.163
M10.93 Gout, unspecified (Forearm)	0.837	0.162
M11.9 Crystal arthropathy, unspecified	0.838	0.162
M05.29 Rheumatoid vasculitis (Site unspecified)	0.838	0.161
M12.30 Palindromic rheumatism (Multiple sites)	0.839	0.161
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.840	0.160
M10.98 Gout, unspecified (Other)	0.841	0.159
M10.95 Gout, unspecified (Pelvic region and thigh)	0.841	0.159
M10.91 Gout, unspecified (Shoulder region)	0.841	0.159
M07.34 Other psoriatic arthropathies (Hand)	0.842	0.158
M05.28 Rheumatoid vasculitis (Other)	0.842	0.158
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.842	0.158
M05.26 Rheumatoid vasculitis (Lower leg)	0.842	0.158
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.842	0.158
M05.24 Rheumatoid vasculitis (Hand)	0.842	0.158
M05.23 Rheumatoid vasculitis (Forearm)	0.842	0.158
M05.22 Rheumatoid vasculitis (Upper arm)	0.842	0.158
M05.21 Rheumatoid vasculitis (Shoulder region)	0.842	0.158
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.842	0.158
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.842	0.158
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.842	0.158
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.842	0.158
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.842	0.158
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.842	0.158
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.842	0.158
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.842	0.158
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.842	0.158
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.842	0.158
M07.19 Arthritis mutilans (Site unspecified)	0.842	0.158
M07.18 Arthritis mutilans (Other)	0.842	0.158
M07.17 Arthritis mutilans (Ankle and foot)	0.842	0.158
M07.16 Arthritis mutilans (Lower leg)	0.842	0.158
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.842	0.158
M07.14 Arthritis mutilans (Hand)	0.842	0.158
M07.13 Arthritis mutilans (Forearm)	0.842	0.158
M07.12 Arthritis mutilans (Upper arm)	0.842	0.158
M07.11 Arthritis mutilans (Shoulder region)	0.842	0.158
M07.10 Arthritis mutilans (Multiple sites)	0.842	0.158
M07.29 Psoriatic spondylitis (Site unspecified)	0.842	0.158
M07.28 Psoriatic spondylitis (Other)	0.842	0.158
M07.27 Psoriatic spondylitis (Ankle and foot)	0.842	0.158
M07.26 Psoriatic spondylitis (Lower leg)	0.842	0.158
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.842	0.158
M07.24 Psoriatic spondylitis (Hand)	0.842	0.158
M07.23 Psoriatic spondylitis (Forearm)	0.842	0.158
M07.22 Psoriatic spondylitis (Upper arm)	0.842	0.158
M07.21 Psoriatic spondylitis (Shoulder region)	0.842	0.158
M07.20 Psoriatic spondylitis (Multiple sites)	0.842	0.158
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.842	0.158
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.842	0.158
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.842	0.158
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.842	0.158
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.842	0.158
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.842	0.158
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.842	0.158
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.842	0.158
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.842	0.158
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.842	0.158
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.842	0.158
M07.58 Arthropathy in ulcerative colitis (Other)	0.842	0.158
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.842	0.158
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.842	0.158
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.842	0.158
M07.54 Arthropathy in ulcerative colitis (Hand)	0.842	0.158
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.842	0.158
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.842	0.158
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.842	0.158
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.842	0.158
M07.69 Other enteropathic arthropathies (Site unspecified)	0.842	0.158
M07.68 Other enteropathic arthropathies (Other)	0.842	0.158
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.842	0.158
M07.66 Other enteropathic arthropathies (Lower leg)	0.842	0.158
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.842	0.158
M07.64 Other enteropathic arthropathies (Hand)	0.842	0.158
M07.63 Other enteropathic arthropathies (Forearm)	0.842	0.158
M07.62 Other enteropathic arthropathies (Upper arm)	0.842	0.158
M07.61 Other enteropathic arthropathies (Shoulder region)	0.842	0.158
M07.60 Other enteropathic arthropathies (Multiple sites)	0.842	0.158
J45 Asthma	0.843	0.157
M12.39 Palindromic rheumatism (Site unspecified)	0.843	0.157
M10.06 Idiopathic gout (Lower leg)	0.843	0.157
M05.20 Rheumatoid vasculitis (Multiple sites)	0.843	0.156
M05.09 Felty's syndrome (Site unspecified)	0.843	0.156
M05.08 Felty's syndrome (Other)	0.843	0.156
M05.07 Felty's syndrome (Ankle and foot)	0.843	0.156
M05.06 Felty's syndrome (Lower leg)	0.843	0.156
M05.05 Felty's syndrome (Pelvic region and thigh)	0.843	0.156
M05.04 Felty's syndrome (Hand)	0.843	0.156
M05.03 Felty's syndrome (Forearm)	0.843	0.156
M05.02 Felty's syndrome (Upper arm)	0.843	0.156
M05.01 Felty's syndrome (Shoulder region)	0.843	0.156
M05.00 Felty's syndrome (Multiple sites)	0.843	0.156
M05.19 Rheumatoid lung disease (Site unspecified)	0.843	0.156
M05.18 Rheumatoid lung disease (Other)	0.843	0.156
M05.17 Rheumatoid lung disease (Ankle and foot)	0.843	0.156
M05.16 Rheumatoid lung disease (Lower leg)	0.843	0.156
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.843	0.156
M05.14 Rheumatoid lung disease (Hand)	0.843	0.156
M05.13 Rheumatoid lung disease (Forearm)	0.843	0.156
M05.12 Rheumatoid lung disease (Upper arm)	0.843	0.156
M05.11 Rheumatoid lung disease (Shoulder region)	0.843	0.156
M05.10 Rheumatoid lung disease (Multiple sites)	0.843	0.156
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.843	0.156
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.843	0.156
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.843	0.156
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.843	0.156
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.843	0.156
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.843	0.156
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.843	0.156
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.843	0.156
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.843	0.156
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.843	0.156
J42 Unspecified chronic bronchitis	0.846	0.154
J41.0 Simple chronic bronchitis	0.846	0.153
M12.38 Palindromic rheumatism (Other)	0.849	0.150
M12.37 Palindromic rheumatism (Ankle and foot)	0.849	0.150
M12.36 Palindromic rheumatism (Lower leg)	0.849	0.150
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.849	0.150
M12.34 Palindromic rheumatism (Hand)	0.849	0.150
M12.33 Palindromic rheumatism (Forearm)	0.849	0.150
M12.32 Palindromic rheumatism (Upper arm)	0.849	0.150
M12.31 Palindromic rheumatism (Shoulder region)	0.849	0.150
E65 Localised adiposity	0.850	0.150
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.851	0.149
E07.1 Dyshormogenetic goitre	0.852	0.147
E07.0 Hypersecretion of calcitonin	0.852	0.147
M11.2 Other chondrocalcinosis	0.854	0.146
M10.08 Idiopathic gout (Other)	0.854	0.146
M10.05 Idiopathic gout (Pelvic region and thigh)	0.854	0.146
M10.04 Idiopathic gout (Hand)	0.854	0.146
M10.03 Idiopathic gout (Forearm)	0.854	0.146
M10.01 Idiopathic gout (Shoulder region)	0.854	0.146
E20-E35 Disorders of other endocrine glands	0.855	0.145
M14.8 Arthropathies in other specified diseases classified elsewhere	0.856	0.143
M10.19 Lead-induced gout (Site unspecified)	0.857	0.143
M10.18 Lead-induced gout (Other)	0.857	0.143
M10.17 Lead-induced gout (Ankle and foot)	0.857	0.143
M10.16 Lead-induced gout (Lower leg)	0.857	0.143
M10.15 Lead-induced gout (Pelvic region and thigh)	0.857	0.143
M10.14 Lead-induced gout (Hand)	0.857	0.143
M10.13 Lead-induced gout (Forearm)	0.857	0.143
M10.12 Lead-induced gout (Upper arm)	0.857	0.143
M10.11 Lead-induced gout (Shoulder region)	0.857	0.143
M10.10 Lead-induced gout (Multiple sites)	0.857	0.143
M10.29 Drug-induced gout (Site unspecified)	0.857	0.143
M10.28 Drug-induced gout (Other)	0.857	0.143
M10.27 Drug-induced gout (Ankle and foot)	0.857	0.143
M10.26 Drug-induced gout (Lower leg)	0.857	0.143
M10.25 Drug-induced gout (Pelvic region and thigh)	0.857	0.143
M10.24 Drug-induced gout (Hand)	0.857	0.143
M10.23 Drug-induced gout (Forearm)	0.857	0.143
M10.22 Drug-induced gout (Upper arm)	0.857	0.143
M10.21 Drug-induced gout (Shoulder region)	0.857	0.143

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations