TreeWAS – Variant ID: rs2254546

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y83.1 Surgical operation with implant of artificial internal device	0.000	0.845	0.155
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.850	0.150
Y83.2 Surgical operation with anastomosis, bypass or graft	0.000	0.859	0.141
Y83.3 Surgical operation with formation of external stoma	0.000	0.860	0.140
Y83.0 Surgical operation with transplant of whole organ	0.000	0.866	0.134
Y83.4 Other reconstructive surgery	0.000	0.878	0.122
Y83.9 Surgical procedure, unspecified	0.000	0.883	0.117
Y83.5 Amputation of limb(s)	0.000	0.904	0.095
Y83.8 Other surgical procedures	0.000	0.917	0.083
Y83.6 Removal of other organ (partial) (total)	0.000	0.937	0.063
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.958	0.042
I35.0 Aortic (valve) stenosis	0.000	0.967	0.033
Z48.8 Other specified surgical follow-up care	0.000	0.978	0.022
Z48.0 Attention to surgical dressings and sutures	0.000	0.979	0.021
E87.6 Hypokalaemia	0.000	0.980	0.020
Z48 Other surgical follow-up care	0.000	0.980	0.020
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.980	0.020
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.981	0.019
Y84.4 Aspiration of fluid	0.000	0.982	0.018
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.982	0.018
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.983	0.017
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.983	0.017
E87.7 Fluid overload	0.000	0.983	0.017
E87.5 Hyperkalaemia	0.000	0.983	0.017
E87.2 Acidosis	0.000	0.984	0.016
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.984	0.016
M16.9 Coxarthrosis, unspecified	0.000	0.984	0.016
Z48.9 Surgical follow-up care, unspecified	0.000	0.985	0.015
Y84.1 Kidney dialysis	0.000	0.985	0.015
E87.3 Alkalosis	0.000	0.985	0.015
Y84.5 Insertion of gastric or duodenal sound	0.000	0.985	0.015
Y84.3 Shock therapy	0.000	0.985	0.015
Y84.9 Medical procedure, unspecified	0.000	0.985	0.014
E87.0 Hyperosmolality and hypernatraemia	0.000	0.986	0.014
Y84.7 Blood-sampling	0.000	0.986	0.014
E87.4 Mixed disorder of acid-base balance	0.000	0.986	0.014
Y84.6 Urinary catheterisation	0.000	0.986	0.014
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.987	0.013
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.987	0.013
T82.1 Mechanical complication of cardiac electronic device	0.000	0.989	0.011
I35 Nonrheumatic aortic valve disorders	0.000	0.989	0.011
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.000	0.989	0.011
I35.9 Aortic valve disorder, unspecified	0.000	0.990	0.010
E66.9 Obesity, unspecified	0.000	0.991	0.009
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.991	0.009
Y84.8 Other medical procedures	0.000	0.991	0.009
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.992	0.008
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.992	0.008
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.992	0.008
H54.4 Blindness, one eye	0.000	0.992	0.008
I35.8 Other aortic valve disorders	0.000	0.993	0.007
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.993	0.007
H54.9 Unspecified visual impairment (binocular)	0.000	0.993	0.007
H54 Blindness and low vision	0.000	0.993	0.007
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.993	0.007
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.993	0.007
Y84.0 Cardiac catheterisation	0.000	0.993	0.007
H54.0 Blindness, both eyes	0.000	0.994	0.006
T21 Burn and corrosion of trunk	0.000	0.994	0.006
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.000	0.994	0.006
I35.1 Aortic (valve) insufficiency	0.000	0.994	0.006
T20-T25 Burns and corrosions of external body surface, specified by site	0.000	0.994	0.006
H54.3 Unqualified visual loss, both eyes	0.000	0.994	0.006
T21.0 Burn of unspecified degree of trunk	0.000	0.994	0.006
H54.6 Unqualified visual loss, one eye	0.000	0.994	0.006
T25 Burn and corrosion of ankle and foot	0.000	0.994	0.005
T21.3 Burn of third degree of trunk	0.000	0.995	0.005
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
T82.3 Mechanical complication of other vascular grafts	0.000	0.995	0.005
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.995	0.005
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
H54.2 Low vision, both eyes	0.000	0.995	0.005
T21.2 Burn of second degree of trunk	0.000	0.995	0.005
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
H54.5 Low vision, one eye	0.000	0.995	0.005
E66 Obesity	0.000	0.995	0.005
T21.1 Burn of first degree of trunk	0.000	0.995	0.005
H54.1 Blindness, one eye, low vision, other eye	0.000	0.995	0.005
T25.2 Burn of second degree of ankle and foot	0.000	0.995	0.005
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.995	0.005
T20 Burn and corrosion of head and neck	0.000	0.995	0.005
T21.7 Corrosion of third degree of trunk	0.000	0.995	0.005
T21.6 Corrosion of second degree of trunk	0.000	0.995	0.005
T21.5 Corrosion of first degree of trunk	0.000	0.995	0.005
T21.4 Corrosion of unspecified degree of trunk	0.000	0.995	0.005
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.995	0.005
T25.0 Burn of unspecified degree of ankle and foot	0.000	0.995	0.005
H70.9 Mastoiditis, unspecified	0.000	0.995	0.005
M25.51 Pain in joint (Shoulder region)	0.005	0.995	0.000
E66.8 Other obesity	0.000	0.995	0.005
H54.7 Unspecified visual loss	0.000	0.995	0.004
T20.2 Burn of second degree of head and neck	0.000	0.995	0.004
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
S22.40 Multiple fractures of ribs (closed)	0.004	0.996	0.000
T25.7 Corrosion of third degree of ankle and foot	0.000	0.996	0.004
T25.6 Corrosion of second degree of ankle and foot	0.000	0.996	0.004
T25.5 Corrosion of first degree of ankle and foot	0.000	0.996	0.004
T25.4 Corrosion of unspecified degree of ankle and foot	0.000	0.996	0.004
T25.1 Burn of first degree of ankle and foot	0.000	0.996	0.004
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T25.3 Burn of third degree of ankle and foot	0.000	0.996	0.004
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
K26 Duodenal ulcer	0.000	0.996	0.004
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T86.0 Bone-marrow transplant rejection	0.000	0.996	0.004
O03.9 Complete or unspecified, without complication	0.000	0.996	0.004
E66.1 Drug-induced obesity	0.000	0.996	0.004
T86 Failure and rejection of transplanted organs and tissues	0.000	0.996	0.004
Z92.2 Personal history of long-term (current) use of other medicaments	0.000	0.996	0.004
T86.1 Kidney transplant failure and rejection	0.000	0.996	0.004
R40.0 Somnolence	0.000	0.996	0.004
T20.3 Burn of third degree of head and neck	0.000	0.996	0.004
T20.7 Corrosion of third degree of head and neck	0.000	0.996	0.004
T20.6 Corrosion of second degree of head and neck	0.000	0.996	0.004
T20.5 Corrosion of first degree of head and neck	0.000	0.996	0.004
T20.4 Corrosion of unspecified degree of head and neck	0.000	0.996	0.004
K26.1 Acute with perforation	0.000	0.996	0.004
E66.0 Obesity due to excess calories	0.000	0.996	0.003
T20.1 Burn of first degree of head and neck	0.000	0.996	0.003
K26.0 Acute with haemorrhage	0.000	0.996	0.003
E04.0 Non-toxic diffuse goitre	0.000	0.997	0.003
H70 Mastoiditis and related conditions	0.000	0.997	0.003
E04.2 Non-toxic multinodular goitre	0.000	0.997	0.003
T23 Burn and corrosion of wrist and hand	0.000	0.997	0.003
L43.9 Lichen planus, unspecified	0.003	0.997	0.000
T86.4 Liver transplant failure and rejection	0.000	0.997	0.003
Y84.2 Radiological procedure and radiotherapy	0.001	0.997	0.003
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.997	0.003
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.997	0.003
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.997	0.003
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.997	0.003
K26.2 Acute with both haemorrhage and perforation	0.000	0.997	0.003
T43.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.997	0.003
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.997	0.003
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
E04 Other non-toxic goitre	0.000	0.997	0.003
K26.5 Chronic or unspecified with perforation	0.000	0.997	0.003
K26.3 Acute without haemorrhage or perforation	0.000	0.997	0.003
T86.3 Heart-lung transplant failure and rejection	0.000	0.997	0.003
T86.2 Heart transplant failure and rejection	0.000	0.997	0.003
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
T20.0 Burn of unspecified degree of head and neck	0.000	0.997	0.003
T23.1 Burn of first degree of wrist and hand	0.000	0.997	0.003
H70.1 Chronic mastoiditis	0.000	0.997	0.003
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.997	0.003
H70.0 Acute mastoiditis	0.000	0.997	0.003
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.997	0.003
N39.9 Disorder of urinary system, unspecified	0.000	0.997	0.003
T90.9 Sequelae of unspecified injury of head	0.000	0.997	0.003
H70.2 Petrositis	0.000	0.997	0.003
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.997	0.003
T91 Sequelae of injuries of neck and trunk	0.000	0.997	0.003
T23.7 Corrosion of third degree of wrist and hand	0.000	0.997	0.002
T23.6 Corrosion of second degree of wrist and hand	0.000	0.997	0.002
T23.5 Corrosion of first degree of wrist and hand	0.000	0.997	0.002
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.997	0.002
H73 Other disorders of tympanic membrane	0.000	0.997	0.003
E04.1 Non-toxic single thyroid nodule	0.000	0.997	0.003
H66 Suppurative and unspecified otitis media	0.000	0.997	0.003
E04.9 Non-toxic goitre, unspecified	0.000	0.997	0.003
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
H65-H75 Diseases of middle ear and mastoid	0.000	0.997	0.003
K91.4 Colostomy and enterostomy malfunction	0.000	0.997	0.003
H66.3 Other chronic suppurative otitis media	0.000	0.997	0.003
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
M25.57 Pain in joint (Ankle and foot)	0.000	0.997	0.003
K26.7 Chronic without haemorrhage or perforation	0.000	0.997	0.002
E04.8 Other specified non-toxic goitre	0.000	0.997	0.002
E03.9 Hypothyroidism, unspecified	0.003	0.997	0.000
H81.0 Meniere's disease	0.000	0.997	0.003
T23.3 Burn of third degree of wrist and hand	0.000	0.997	0.002
H70.8 Other mastoiditis and related conditions	0.000	0.998	0.002
H81.9 Disorder of vestibular function, unspecified	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.998	0.002
T90.5 Sequelae of intracranial injury	0.000	0.998	0.002
T90.0 Sequelae of superficial injury of head	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
H71 Cholesteatoma of middle ear	0.000	0.998	0.002
F32.1 Moderate depressive episode	0.002	0.998	0.000
H69 Other disorders of Eustachian tube	0.000	0.998	0.002
E65-E68 Obesity and other hyperalimentation	0.000	0.998	0.002
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.000	0.998	0.002
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.002
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.998	0.002
H66.0 Acute suppurative otitis media	0.000	0.998	0.002
S22.4 Multiple fractures of ribs	0.002	0.998	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
H66.4 Suppurative otitis media, unspecified	0.000	0.998	0.002
H73.0 Acute myringitis	0.000	0.998	0.002
K56.7 Ileus, unspecified	0.000	0.998	0.002
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.998	0.002
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.998	0.002
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.998	0.002
O72.1 Other immediate postpartum haemorrhage	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
H81 Disorders of vestibular function	0.000	0.998	0.002
H74.4 Polyp of middle ear	0.000	0.998	0.002
N18.5 Chronic kidney disease, stage 5	0.000	0.998	0.002
H73.1 Chronic myringitis	0.000	0.998	0.002
T91.3 Sequelae of injury of spinal cord	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.998	0.002
H67 Otitis media in diseases classified elsewhere	0.000	0.998	0.002
H69.8 Other specified disorders of Eustachian tube	0.000	0.998	0.002
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.000	0.998	0.002
H81.3 Other peripheral vertigo	0.000	0.998	0.002
T23.2 Burn of second degree of wrist and hand	0.000	0.998	0.002
H68 Eustachian salpingitis and obstruction	0.000	0.998	0.002
J35.1 Hypertrophy of tonsils	0.000	0.998	0.002
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.998	0.002
T91.1 Sequelae of fracture of spine	0.000	0.998	0.002
J47 Bronchiectasis	0.000	0.998	0.002
H74 Other disorders of middle ear and mastoid	0.000	0.998	0.002
K01.1 Impacted teeth	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.998	0.002
H69.0 Patulous Eustachian tube	0.000	0.998	0.002
K82.4 Cholesterolosis of gallbladder	0.002	0.998	0.000
E67 Other hyperalimentation	0.000	0.998	0.002
E68 Sequelae of hyperalimentation	0.000	0.998	0.002
E83.3 Disorders of phosphorus metabolism	0.000	0.998	0.002
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
H66.9 Otitis media, unspecified	0.000	0.998	0.002
H81.4 Vertigo of central origin	0.000	0.998	0.002
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.998	0.002
N95.1 Menopausal and female climacteric states	0.000	0.998	0.002
T90.3 Sequelae of injury of cranial nerves	0.000	0.998	0.002
F32.0 Mild depressive episode	0.002	0.998	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.998	0.002
S22.41 Multiple fractures of ribs (open)	0.002	0.998	0.000
H81.8 Other disorders of vestibular function	0.000	0.998	0.002
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.998	0.002
T90.8 Sequelae of other specified injuries of head	0.000	0.998	0.002
E11.2 With renal complications	0.000	0.998	0.002
R22.0 Localised swelling, mass and lump, head	0.000	0.998	0.002
T90.1 Sequelae of open wound of head	0.000	0.998	0.002
E73.9 Lactose intolerance, unspecified	0.000	0.998	0.002
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.998	0.002
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.998	0.002
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.998	0.002
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.998	0.002
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
H81.1 Benign paroxysmal vertigo	0.000	0.998	0.002
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
L43 Lichen planus	0.002	0.998	0.000
E70-E90 Metabolic disorders	0.000	0.998	0.002
M16.5 Other posttraumatic coxarthrosis	0.000	0.998	0.002
Z88.5 Personal history of allergy to narcotic agent	0.000	0.998	0.002
E83 Disorders of mineral metabolism	0.000	0.998	0.002
E73 Lactose intolerance	0.000	0.998	0.002
E03.8 Other specified hypothyroidism	0.002	0.998	0.000
K26.4 Chronic or unspecified with haemorrhage	0.000	0.998	0.002
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.000	0.998	0.002
H68.0 Eustachian salpingitis	0.000	0.998	0.002
H74.1 Adhesive middle ear disease	0.000	0.998	0.002
T85 Complications of other internal prosthetic devices, implants and grafts	0.000	0.998	0.002
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.998	0.002
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.000	0.998	0.002
H68.1 Obstruction of Eustachian tube	0.000	0.998	0.002
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.998	0.002
E83.4 Disorders of magnesium metabolism	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
H72 Perforation of tympanic membrane	0.000	0.998	0.002
E79 Disorders of purine and pyrimidine metabolism	0.000	0.998	0.002
E67.8 Other specified hyperalimentation	0.000	0.998	0.001
E67.3 Hypervitaminosis D	0.000	0.998	0.001
E67.2 Megavitamin-B6 syndrome	0.000	0.998	0.001
E67.1 Hypercarotenaemia	0.000	0.998	0.001
E67.0 Hypervitaminosis A	0.000	0.998	0.001
T80 Complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
L43.8 Other lichen planus	0.002	0.998	0.000
E03 Other hypothyroidism	0.001	0.998	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.998	0.002
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
T85.2 Mechanical complication of intraocular lens	0.000	0.998	0.002
T90.4 Sequelae of injury of eye and orbit	0.000	0.998	0.002
M16 Coxarthrosis [arthrosis of hip]	0.000	0.998	0.002
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.998	0.001
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.998	0.002
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
R40 Somnolence, stupor and coma	0.000	0.998	0.002
E84 Cystic fibrosis	0.000	0.998	0.001
E77 Disorders of glycoprotein metabolism	0.000	0.998	0.001
E76 Disorders of glycosaminoglycan metabolism	0.000	0.998	0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.998	0.001
E70 Disorders of aromatic amino-acid metabolism	0.000	0.998	0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.998	0.001
D11.0 Parotid gland	0.002	0.998	0.000
E73.8 Other lactose intolerance	0.000	0.998	0.001
E73.1 Secondary lactase deficiency	0.000	0.998	0.001
E73.0 Congenital lactase deficiency	0.000	0.998	0.001
E83.8 Other disorders of mineral metabolism	0.000	0.998	0.001
E83.2 Disorders of zinc metabolism	0.000	0.998	0.001
E83.0 Disorders of copper metabolism	0.000	0.998	0.001
L43.3 Subacute (active) lichen planus	0.001	0.998	0.000
L43.2 Lichenoid drug reaction	0.001	0.998	0.000
L43.1 Bullous lichen planus	0.001	0.998	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.000	0.998	0.002
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.998	0.002
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.998	0.001
H81.2 Vestibular neuronitis	0.000	0.998	0.001
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.998	0.002
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.998	0.002
Z84.8 Family history of other specified conditions	0.000	0.998	0.002
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.998	0.001
E72 Other disorders of amino-acid metabolism	0.000	0.998	0.001
S43.0 Dislocation of shoulder joint	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.002
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.998	0.001
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.998	0.001
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.998	0.001
E79.1 Lesch-Nyhan syndrome	0.000	0.998	0.001
H74.0 Tympanosclerosis	0.000	0.998	0.001
M16.6 Other secondary coxarthrosis, bilateral	0.000	0.998	0.001
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.001
E65 Localised adiposity	0.000	0.998	0.001
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.001	0.998	0.000
F10.1 Harmful use	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.000	0.999	0.001
E03.5 Myxoedema coma	0.001	0.999	0.000
E03.4 Atrophy of thyroid (acquired)	0.001	0.999	0.000
E03.3 Postinfectious hypothyroidism	0.001	0.999	0.000
E75.2 Other sphingolipidosis	0.000	0.999	0.001
E84.9 Cystic fibrosis, unspecified	0.000	0.999	0.001
H72.2 Other marginal perforations of tympanic membrane	0.000	0.999	0.001
M16.3 Other dysplastic coxarthrosis	0.000	0.999	0.001
T31.0 Burns involving less than 10% of body surface	0.000	0.999	0.001
T80.6 Other serum reactions	0.000	0.999	0.001
T80.5 Anaphylactic shock due to serum	0.000	0.999	0.001
T80.4 Rh incompatibility reaction	0.000	0.999	0.001
T80.3 ABO incompatibility reaction	0.000	0.999	0.001
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.000	0.999	0.001
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.999	0.001
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.999	0.001
H72.1 Attic perforation of tympanic membrane	0.000	0.999	0.001
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.999	0.001
L43.0 Hypertrophic lichen planus	0.001	0.999	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.999	0.001
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.000	0.999	0.001
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.999	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.999	0.001
K91.1 Postgastric surgery syndromes	0.000	0.999	0.001
M16.4 Posttraumatic coxarthrosis, bilateral	0.000	0.999	0.001
N18.9 Chronic renal failure, unspecified	0.000	0.999	0.001
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.999	0.001
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.999	0.001
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.999	0.001
E70.3 Albinism	0.000	0.999	0.001
E70.2 Disorders of tyrosine metabolism	0.000	0.999	0.001
E70.1 Other hyperphenylalaninaemias	0.000	0.999	0.001
E70.0 Classical phenylketonuria	0.000	0.999	0.001
E84.8 Cystic fibrosis with other manifestations	0.000	0.999	0.001
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.999	0.001
H34.8 Other retinal vascular occlusions	0.001	0.999	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.001	0.999	0.000
E71.3 Disorders of fatty-acid metabolism	0.000	0.999	0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.999	0.001
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.999	0.001
E71.0 Maple-syrup-urine disease	0.000	0.999	0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.999	0.001
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.999	0.001
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.999	0.001
E76.2 Other mucopolysaccharidoses	0.000	0.999	0.001
E76.1 Mucopolysaccharidosis, type II	0.000	0.999	0.001
E76.0 Mucopolysaccharidosis, type I	0.000	0.999	0.001
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.999	0.001
E77.8 Other disorders of glycoprotein metabolism	0.000	0.999	0.001
E77.1 Defects in glycoprotein degradation	0.000	0.999	0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.999	0.001
O03 Spontaneous abortion	0.000	0.999	0.001
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.999	0.001
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.999	0.001
E72.5 Disorders of glycine metabolism	0.000	0.999	0.001
E72.4 Disorders of ornithine metabolism	0.000	0.999	0.001
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.999	0.001
E72.2 Disorders of urea cycle metabolism	0.000	0.999	0.001
E75.6 Lipid storage disorder, unspecified	0.000	0.999	0.001
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.999	0.001
E75.3 Sphingolipidosis, unspecified	0.000	0.999	0.001
E75.1 Other gangliosidosis	0.000	0.999	0.001
E75.0 GM2 gangliosidosis	0.000	0.999	0.001
F60.9 Personality disorder, unspecified	0.001	0.999	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.999	0.001
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.999	0.001
T40.2 Other opioids	0.001	0.999	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.000	0.999	0.001
D89.3 Immune reconstitution syndrome	0.000	0.999	0.001
E03.1 Congenital hypothyroidism without goitre	0.001	0.999	0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.999	0.001
E72.0 Disorders of amino-acid transport	0.000	0.999	0.001
E83.1 Disorders of iron metabolism	0.000	0.999	0.001
N92.6 Irregular menstruation, unspecified	0.000	0.999	0.001
S43.1 Dislocation of acromioclavicular joint	0.001	0.999	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.001	0.999	0.000
Z01.6 Radiological examination, not elsewhere classified	0.001	0.999	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.999	0.001
T94 Sequelae of injuries involving multiple and unspecified body regions	0.000	0.999	0.001
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.000	0.999	0.001
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.999	0.001
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.999	0.001
R40.1 Stupor	0.000	0.999	0.001
T83.2 Mechanical complication of graft of urinary organ	0.000	0.999	0.001
Z94.2 Lung transplant status	0.000	0.999	0.001
J32.9 Chronic sinusitis, unspecified	0.000	0.999	0.001
T39.1 4-Aminophenol derivatives	0.001	0.999	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.999	0.001
Z94.1 Heart transplant status	0.000	0.999	0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.999	0.001
E80.6 Other disorders of bilirubin metabolism	0.000	0.999	0.001
I69.0 Sequelae of subarachnoid haemorrhage	0.001	0.999	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.001	0.999	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.999	0.001
X23.9 Unspecified place	0.000	0.999	0.001
X23.8 Other specified place	0.000	0.999	0.001
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
E11.8 With unspecified complications	0.000	0.999	0.001
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.999	0.001
L08.0 Pyoderma	0.000	0.999	0.001
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.000	0.999	0.001
R40.2 Coma, unspecified	0.000	0.999	0.001
T94.0 Sequelae of injuries involving multiple body regions	0.000	0.999	0.001
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.000	0.999	0.001
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.999	0.001
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.001	0.999	0.000
T87 Complications peculiar to reattachment and amputation	0.000	0.999	0.001
T95 Sequelae of burns, corrosions and frostbite	0.000	0.999	0.001
D84.1 Defects in the complement system	0.000	0.999	0.001
E11.0 With coma	0.000	0.999	0.001
E14.3 With ophthalmic complications	0.000	0.999	0.001
E75.5 Other lipid storage disorders	0.000	0.999	0.001
F23.9 Acute and transient psychotic disorder, unspecified	0.001	0.999	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.999	0.001
K91.5 Postcholecystectomy syndrome	0.000	0.999	0.001
O03.7 Complete or unspecified, complicated by embolism	0.000	0.999	0.001
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.999	0.001
O03.2 Incomplete, complicated by embolism	0.000	0.999	0.001
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.999	0.001
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.999	0.001
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.999	0.001
T94.1 Sequelae of injuries, not specified by body region	0.000	0.999	0.001
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.000	0.999	0.001
Z94.7 Corneal transplant status	0.000	0.999	0.001
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.000	0.999	0.001
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.999	0.001
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.999	0.001
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.999	0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.999	0.001
E74.2 Disorders of galactose metabolism	0.000	0.999	0.001
E74.1 Disorders of fructose metabolism	0.000	0.999	0.001
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.999	0.001
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.001	0.999	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.000	0.999	0.001
T87.3 Neuroma of amputation stump	0.001	0.999	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.999	0.001
S82.00 Fracture of patella (closed)	0.001	0.999	0.000
E11.7 With multiple complications	0.000	0.999	0.001
E83.5 Disorders of calcium metabolism	0.000	0.999	0.001
F60.7 Dependent personality disorder	0.001	0.999	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.001	0.999	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.999	0.001
X62.9 Unspecified place	0.001	0.999	0.000
T36 Poisoning by systemic antibiotics	0.001	0.999	0.000
Z94 Transplanted organ and tissue status	0.000	0.999	0.001
F60.3 Emotionally unstable personality disorder	0.001	0.999	0.000
L03.0 Cellulitis of finger and toe	0.000	0.999	0.001
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.999	0.001
T36.3 Macrolides	0.001	0.999	0.000
T36.0 Penicillins	0.001	0.999	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.001	0.999	0.000
T48.5 Anti-common-cold drugs	0.001	0.999	0.000
L08 Other local infections of skin and subcutaneous tissue	0.000	0.999	0.001
H53-H54 Visual disturbances and blindness	0.000	0.999	0.001
T36-T50 Poisoning by drugs, medicaments and biological substances	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.999	0.001
E11.1 With ketoacidosis	0.000	0.999	0.001
E74.0 Glycogen storage disease	0.000	0.999	0.001
O03.3 Incomplete, with other and unspecified complications	0.000	0.999	0.001
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
T48.4 Expectorants	0.001	0.999	0.000
T48.3 Antitussives	0.001	0.999	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
T48.0 Oxytocic drugs	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations