TreeWAS – Variant ID: rs2257126

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
E10.9 Without complications	0.986	0.014	0.000
E10 Insulin-dependent diabetes mellitus	0.986	0.014	0.000
E10.3 With ophthalmic complications	0.984	0.016	0.000
E10.1 With ketoacidosis	0.911	0.089	0.000
E10.2 With renal complications	0.846	0.154	0.000
E10.6 With other specified complications	0.811	0.189	0.000
E10.0 With coma	0.784	0.216	0.000
E10.7 With multiple complications	0.762	0.238	0.000
E10.5 With peripheral circulatory complications	0.742	0.258	0.000
E10.8 With unspecified complications	0.707	0.293	0.000
K90 Intestinal malabsorption	0.542	0.458	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.417	0.583	0.000
J47 Bronchiectasis	0.415	0.585	0.000
K90.9 Intestinal malabsorption, unspecified	0.412	0.588	0.000
E10.4 With neurological complications	0.397	0.603	0.000
K90.3 Pancreatic steatorrhoea	0.389	0.611	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.389	0.611	0.000
K90.1 Tropical sprue	0.389	0.611	0.000
K90.8 Other intestinal malabsorption	0.380	0.620	0.000
E10-E14 Diabetes mellitus	0.234	0.766	0.000
E53.8 Deficiency of other specified B group vitamins	0.175	0.825	0.000
E53 Deficiency of other B group vitamins	0.172	0.828	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.171	0.829	0.000
E50-E64 Other nutritional deficiencies	0.169	0.831	0.000
E12 Malnutrition-related diabetes mellitus	0.168	0.832	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.159	0.841	0.000
E16 Other disorders of pancreatic internal secretion	0.152	0.848	0.000
E13 Other specified diabetes mellitus	0.146	0.854	0.000
E16.2 Hypoglycaemia, unspecified	0.146	0.854	0.000
E40-E46 Malnutrition	0.140	0.860	0.000
W19.9 Unspecified place	0.135	0.865	0.000
E58 Dietary calcium deficiency	0.131	0.869	0.000
E53.9 Vitamin B deficiency, unspecified	0.130	0.869	0.000
E54 Ascorbic acid deficiency	0.128	0.872	0.000
E51 Thiamine deficiency	0.126	0.873	0.000
E53.1 Pyridoxine deficiency	0.123	0.877	0.000
E53.0 Riboflavin deficiency	0.123	0.877	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.121	0.879	0.000
E63 Other nutritional deficiencies	0.121	0.879	0.000
E56 Other vitamin deficiencies	0.121	0.879	0.000
E50 Vitamin A deficiency	0.121	0.879	0.000
E60 Dietary zinc deficiency	0.121	0.879	0.000
E59 Dietary selenium deficiency	0.121	0.879	0.000
E52 Niacin deficiency [pellagra]	0.121	0.879	0.000
E12.9 Without complications	0.121	0.879	0.000
E12.8 With unspecified complications	0.121	0.879	0.000
E12.7 With multiple complications	0.121	0.879	0.000
E12.6 With other specified complications	0.121	0.879	0.000
E12.5 With peripheral circulatory complications	0.121	0.879	0.000
E12.4 With neurological complications	0.121	0.879	0.000
E12.3 With ophthalmic complications	0.121	0.879	0.000
E12.2 With renal complications	0.121	0.879	0.000
E12.1 With ketoacidosis	0.121	0.879	0.000
E12.0 With coma	0.121	0.879	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.120	0.880	0.000
E46 Unspecified protein-energy malnutrition	0.118	0.882	0.000
E15 Nondiabetic hypoglycaemic coma	0.114	0.885	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.109	0.891	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.109	0.891	0.000
E16.4 Abnormal secretion of gastrin	0.109	0.891	0.000
E16.3 Increased secretion of glucagon	0.109	0.891	0.000
E20-E35 Disorders of other endocrine glands	0.108	0.892	0.000
E14 Unspecified diabetes mellitus	0.108	0.892	0.000
E13.8 With unspecified complications	0.105	0.895	0.000
E13.7 With multiple complications	0.105	0.895	0.000
E13.6 With other specified complications	0.105	0.895	0.000
E13.5 With peripheral circulatory complications	0.105	0.895	0.000
E13.4 With neurological complications	0.105	0.895	0.000
E13.2 With renal complications	0.105	0.895	0.000
E13.1 With ketoacidosis	0.105	0.895	0.000
E13.0 With coma	0.105	0.895	0.000
G62.9 Polyneuropathy, unspecified	0.104	0.896	0.000
E13.3 With ophthalmic complications	0.102	0.898	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.101	0.899	0.000
E45 Retarded development following protein-energy malnutrition	0.101	0.899	0.000
E43 Unspecified severe protein-energy malnutrition	0.101	0.899	0.000
E42 Marasmic kwashiorkor	0.101	0.899	0.000
E41 Nutritional marasmus	0.101	0.899	0.000
E40 Kwashiorkor	0.101	0.899	0.000
E16.1 Other hypoglycaemia	0.097	0.903	0.000
E55 Vitamin D deficiency	0.097	0.903	0.000
E51.2 Wernicke's encephalopathy	0.096	0.904	0.000
K90-K93 Other diseases of the digestive system	0.094	0.906	0.000
E22 Hyperfunction of pituitary gland	0.093	0.907	0.000
E51.9 Thiamine deficiency, unspecified	0.091	0.909	0.000
E51.8 Other manifestations of thiamine deficiency	0.091	0.909	0.000
E51.1 Beriberi	0.091	0.909	0.000
E28 Ovarian dysfunction	0.091	0.909	0.000
E61 Deficiency of other nutrient elements	0.088	0.912	0.000
E13.9 Without complications	0.088	0.912	0.000
E50.9 Vitamin A deficiency, unspecified	0.087	0.913	0.000
E50.8 Other manifestations of vitamin A deficiency	0.087	0.913	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.087	0.913	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.087	0.913	0.000
E50.5 Vitamin A deficiency with night blindness	0.087	0.913	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.087	0.913	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.087	0.913	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.087	0.913	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.087	0.913	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.087	0.913	0.000
E56.9 Vitamin deficiency, unspecified	0.087	0.913	0.000
E56.8 Deficiency of other vitamins	0.087	0.913	0.000
E56.1 Deficiency of vitamin K	0.087	0.913	0.000
E56.0 Deficiency of vitamin E	0.087	0.913	0.000
E63.9 Nutritional deficiency, unspecified	0.087	0.913	0.000
E63.8 Other specified nutritional deficiencies	0.087	0.913	0.000
E63.1 Imbalance of constituents of food intake	0.087	0.913	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.087	0.913	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.087	0.913	0.000
E64.8 Sequelae of other nutritional deficiencies	0.087	0.913	0.000
E64.3 Sequelae of rickets	0.087	0.913	0.000
E64.2 Sequelae of vitamin C deficiency	0.087	0.913	0.000
E64.1 Sequelae of vitamin A deficiency	0.087	0.913	0.000
E64.0 Sequelae of protein-energy malnutrition	0.087	0.913	0.000
E14.8 With unspecified complications	0.087	0.913	0.000
E29 Testicular dysfunction	0.086	0.913	0.000
E27.1 Primary adrenocortical insufficiency	0.086	0.914	0.000
E27 Other disorders of adrenal gland	0.086	0.914	0.000
E26 Hyperaldosteronism	0.086	0.914	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.082	0.918	0.000
E14.3 With ophthalmic complications	0.082	0.918	0.000
E31 Polyglandular dysfunction	0.082	0.918	0.000
E14.1 With ketoacidosis	0.080	0.920	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.078	0.922	0.000
E32 Diseases of thymus	0.078	0.922	0.000
E30 Disorders of puberty, not elsewhere classified	0.078	0.922	0.000
E14.7 With multiple complications	0.078	0.922	0.000
E14.0 With coma	0.078	0.922	0.000
E22.1 Hyperprolactinaemia	0.078	0.922	0.000
E14.6 With other specified complications	0.077	0.923	0.000
E20 Hypoparathyroidism	0.077	0.923	0.000
E34 Other endocrine disorders	0.077	0.923	0.000
E28.3 Primary ovarian failure	0.077	0.923	0.000
E14.2 Withrenal complications	0.075	0.925	0.000
G62 Other polyneuropathies	0.075	0.925	0.000
E14.5 With peripheral circulatory complications	0.074	0.926	0.000
E44.1 Mild protein-energy malnutrition	0.072	0.928	0.000
E44.0 Moderate protein-energy malnutrition	0.072	0.928	0.000
K91.4 Colostomy and enterostomy malfunction	0.072	0.928	0.000
E29.1 Testicular hypofunction	0.071	0.929	0.000
E55.0 Rickets, active	0.069	0.930	0.000
E25 Adrenogenital disorders	0.068	0.932	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.068	0.932	0.000
E26.9 Hyperaldosteronism, unspecified	0.067	0.933	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.067	0.933	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.067	0.933	0.000
E22.8 Other hyperfunction of pituitary gland	0.067	0.933	0.000
E28.2 Polycystic ovarian syndrome	0.067	0.933	0.000
E27.2 Addisonian crisis	0.065	0.934	0.000
E28.9 Ovarian dysfunction, unspecified	0.065	0.935	0.000
E28.8 Other ovarian dysfunction	0.065	0.935	0.000
E28.1 Androgen excess	0.065	0.935	0.000
E28.0 Oestrogen excess	0.065	0.935	0.000
E61.2 Magnesium deficiency	0.065	0.935	0.000
E26.0 Primary hyperaldosteronism	0.065	0.935	0.000
E61.9 Deficiency of nutrient element, unspecified	0.063	0.937	0.000
E61.8 Deficiency of other specified nutrient elements	0.063	0.937	0.000
E61.7 Deficiency of multiple nutrient elements	0.063	0.937	0.000
E61.6 Vanadium deficiency	0.063	0.937	0.000
E61.5 Molybdenum deficiency	0.063	0.937	0.000
E61.4 Chromium deficiency	0.063	0.937	0.000
E61.3 Manganese deficiency	0.063	0.937	0.000
E61.0 Copper deficiency	0.063	0.937	0.000
E24 Cushing's syndrome	0.063	0.937	0.000
E14.4 With neurological complications	0.063	0.937	0.000
E31.0 Autoimmune polyglandular failure	0.062	0.937	0.000
E29.9 Testicular dysfunction, unspecified	0.062	0.938	0.000
E29.8 Other testicular dysfunction	0.062	0.938	0.000
E29.0 Testicular hyperfunction	0.062	0.938	0.000
E27.9 Disorder of adrenal gland, unspecified	0.062	0.938	0.000
G62.8 Other specified polyneuropathies	0.062	0.938	0.000
E27.5 Adrenomedullary hyperfunction	0.062	0.938	0.000
E27.0 Other adrenocortical overactivity	0.062	0.938	0.000
E26.8 Other hyperaldosteronism	0.062	0.938	0.000
E26.1 Secondary hyperaldosteronism	0.062	0.938	0.000
G62.0 Drug-induced polyneuropathy	0.061	0.938	0.000
E34.3 Short stature, not elsewhere classified	0.061	0.939	0.000
E65-E68 Obesity and other hyperalimentation	0.060	0.940	0.000
E31.9 Polyglandular dysfunction, unspecified	0.059	0.941	0.000
E31.8 Other polyglandular dysfunction	0.059	0.941	0.000
E31.1 Polyglandular hyperfunction	0.059	0.941	0.000
E34.8 Other specified endocrine disorders	0.056	0.944	0.000
E30.9 Disorder of puberty, unspecified	0.056	0.944	0.000
E30.8 Other disorders of puberty	0.056	0.944	0.000
E30.1 Precocious puberty	0.056	0.944	0.000
E30.0 Delayed puberty	0.056	0.944	0.000
E32.9 Disease of thymus, unspecified	0.056	0.944	0.000
E32.8 Other diseases of thymus	0.056	0.944	0.000
E32.1 Abscess of thymus	0.056	0.944	0.000
E32.0 Persistent hyperplasia of thymus	0.056	0.944	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.056	0.944	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.056	0.944	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.056	0.944	0.000
E20.8 Other hypoparathyroidism	0.056	0.944	0.000
E20.1 Pseudohypoparathyroidism	0.056	0.944	0.000
E20.0 Idiopathic hypoparathyroidism	0.056	0.944	0.000
E34.5 Androgen resistance syndrome	0.055	0.944	0.000
E34.4 Constitutional tall stature	0.055	0.944	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.055	0.944	0.000
E34.1 Other hypersecretion of intestinal hormones	0.055	0.944	0.000
E20.9 Hypoparathyroidism, unspecified	0.055	0.945	0.000
G62.2 Polyneuropathy due to other toxic agents	0.054	0.946	0.000
E34.9 Endocrine disorder, unspecified	0.053	0.947	0.000
G62.1 Alcoholic polyneuropathy	0.051	0.949	0.000
E34.0 Carcinoid syndrome	0.049	0.950	0.000
E25.9 Adrenogenital disorder, unspecified	0.049	0.951	0.000
E25.8 Other adrenogenital disorders	0.049	0.951	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.049	0.951	0.000
K93.1 Megacolon in Chagas' disease	0.049	0.951	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.049	0.951	0.000
E00-E07 Disorders of thyroid gland	0.049	0.951	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.047	0.953	0.000
E24.8 Other Cushing's syndrome	0.046	0.953	0.000
K91.5 Postcholecystectomy syndrome	0.046	0.954	0.000
E24.2 Drug-induced Cushing's syndrome	0.046	0.954	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.045	0.954	0.000
E24.3 Ectopic ACTH syndrome	0.045	0.954	0.000
E24.1 Nelson's syndrome	0.045	0.954	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.045	0.955	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.045	0.955	0.000
E22.0 Acromegaly and pituitary gigantism	0.045	0.955	0.000
E55.9 Vitamin D deficiency, unspecified	0.045	0.955	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.044	0.956	0.001
E67 Other hyperalimentation	0.043	0.957	0.000
E68 Sequelae of hyperalimentation	0.043	0.957	0.000
E24.0 Pituitary-dependent Cushing's disease	0.041	0.958	0.000
E05.9 Thyrotoxicosis, unspecified	0.041	0.959	0.000
K91.1 Postgastric surgery syndromes	0.041	0.959	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.039	0.961	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.039	0.961	0.000
E89.2 Postprocedural hypoparathyroidism	0.036	0.964	0.000
E70-E90 Metabolic disorders	0.035	0.965	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.035	0.965	0.000
E00 Congenital iodine-deficiency syndrome	0.035	0.965	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.034	0.965	0.000
E24.9 Cushing's syndrome, unspecified	0.035	0.965	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.035	0.965	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.035	0.965	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.034	0.966	0.000
E05.5 Thyroid crisis or storm	0.034	0.966	0.000
E05.4 Thyrotoxicosis factitia	0.034	0.966	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.034	0.966	0.000
E65 Localised adiposity	0.034	0.966	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.033	0.967	0.000
E89.0 Postprocedural hypothyroidism	0.031	0.969	0.000
E67.8 Other specified hyperalimentation	0.031	0.969	0.000
E67.3 Hypervitaminosis D	0.031	0.969	0.000
E67.2 Megavitamin-B6 syndrome	0.031	0.969	0.000
E67.1 Hypercarotenaemia	0.031	0.969	0.000
E67.0 Hypervitaminosis A	0.031	0.969	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.031	0.969	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.030	0.970	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.030	0.970	0.000
K91.3 Postoperative intestinal obstruction	0.029	0.971	0.000
F20.9 Schizophrenia, unspecified	0.000	0.972	0.028
E70 Disorders of aromatic amino-acid metabolism	0.028	0.972	0.000
F20.0 Paranoid schizophrenia	0.000	0.972	0.028
E77 Disorders of glycoprotein metabolism	0.027	0.972	0.000
E06 Thyroiditis	0.027	0.973	0.000
F20 Schizophrenia	0.000	0.973	0.027
H36.0 Diabetic retinopathy	0.027	0.973	0.000
E61.1 Iron deficiency	0.026	0.974	0.000
E21.2 Other hyperparathyroidism	0.026	0.974	0.000
E23 Hypofunction and other disorders of pituitary gland	0.026	0.974	0.000
E72 Other disorders of amino-acid metabolism	0.026	0.974	0.000
E79 Disorders of purine and pyrimidine metabolism	0.026	0.974	0.000
G61 Inflammatory polyneuropathy	0.026	0.974	0.000
E21.4 Other specified disorders of parathyroid gland	0.025	0.974	0.000
E05.8 Other thyrotoxicosis	0.025	0.974	0.000
E76 Disorders of glycosaminoglycan metabolism	0.025	0.974	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.025	0.974	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.025	0.974	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.025	0.975	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.025	0.975	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.025	0.975	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.025	0.975	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.025	0.975	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.025	0.975	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.025	0.975	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.025	0.975	0.000
E80.6 Other disorders of bilirubin metabolism	0.025	0.975	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.025	0.975	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.025	0.975	0.000
E89.5 Postprocedural testicular hypofunction	0.025	0.975	0.000
E89.1 Postprocedural hypoinsulinaemia	0.025	0.975	0.000
E27.8 Other specified disorders of adrenal gland	0.024	0.975	0.001
E80.1 Porphyria cutanea tarda	0.025	0.975	0.000
G61.8 Other inflammatory polyneuropathies	0.025	0.975	0.000
E84 Cystic fibrosis	0.024	0.976	0.000
E80.2 Other porphyria	0.024	0.976	0.000
E87.5 Hyperkalaemia	0.024	0.976	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.024	0.976	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.023	0.976	0.001
E80.4 Gilbert's syndrome	0.024	0.976	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.022	0.977	0.000
E80.5 Crigler-Najjar syndrome	0.022	0.977	0.000
E80.3 Defects of catalase and peroxydase	0.022	0.977	0.000
E80.0 Hereditary erythropoietic porphyria	0.022	0.977	0.000
E74 Other disorders of carbohydrate metabolism	0.022	0.978	0.000
E70.3 Albinism	0.022	0.978	0.000
E73 Lactose intolerance	0.022	0.978	0.000
G64 Other disorders of peripheral nervous system	0.022	0.978	0.000
E89.4 Postprocedural ovarian failure	0.022	0.978	0.000
E77.8 Other disorders of glycoprotein metabolism	0.022	0.978	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.022	0.978	0.000
G60 Hereditary and idiopathic neuropathy	0.021	0.979	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.021	0.979	0.000
E07 Other disorders of thyroid	0.021	0.979	0.000
E21.3 Hyperparathyroidism, unspecified	0.021	0.979	0.000
F01.9 Vascular dementia, unspecified	0.020	0.979	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.020	0.980	0.000
E06.5 Other chronic thyroiditis	0.020	0.980	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.020	0.980	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.020	0.980	0.000
E70.2 Disorders of tyrosine metabolism	0.020	0.980	0.000
E70.1 Other hyperphenylalaninaemias	0.020	0.980	0.000
E70.0 Classical phenylketonuria	0.020	0.980	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.020	0.980	0.000
E77.1 Defects in glycoprotein degradation	0.020	0.980	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.020	0.980	0.000
E06.4 Drug-induced thyroiditis	0.020	0.980	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.020	0.980	0.000
E06.0 Acute thyroiditis	0.020	0.980	0.000
E06.9 Thyroiditis, unspecified	0.020	0.980	0.000
F20.8 Other schizophrenia	0.000	0.980	0.019
F20.6 Simple schizophrenia	0.000	0.980	0.019
F20.4 Postschizophrenic depression	0.000	0.980	0.019
F20.3 Undifferentiated schizophrenia	0.000	0.980	0.019
F20.2 Catatonic schizophrenia	0.000	0.980	0.019
F20.1 Hebephrenic schizophrenia	0.000	0.980	0.019
E23.7 Disorder of pituitary gland, unspecified	0.019	0.981	0.000
F01 Vascular dementia	0.019	0.981	0.000
A63.0 Anogenital (venereal) warts	0.019	0.981	0.000
E72.0 Disorders of amino-acid transport	0.019	0.981	0.000
F20.5 Residual schizophrenia	0.000	0.981	0.019
E06.1 Subacute thyroiditis	0.019	0.981	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.018	0.981	0.000
E23.1 Drug-induced hypopituitarism	0.018	0.981	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.019	0.981	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.019	0.981	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.019	0.981	0.000
E72.5 Disorders of glycine metabolism	0.019	0.981	0.000
E72.4 Disorders of ornithine metabolism	0.019	0.981	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.019	0.981	0.000
E72.2 Disorders of urea cycle metabolism	0.019	0.981	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.019	0.981	0.000
Q00-Q07 Congenital malformations of the nervous system	0.019	0.981	0.000
G61.1 Serum neuropathy	0.019	0.981	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.018	0.981	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.018	0.981	0.000
E79.1 Lesch-Nyhan syndrome	0.018	0.981	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.019	0.981	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.019	0.981	0.000
E71.3 Disorders of fatty-acid metabolism	0.018	0.981	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.018	0.981	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.018	0.981	0.000
E71.0 Maple-syrup-urine disease	0.018	0.981	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.018	0.981	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.018	0.981	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.018	0.981	0.000
E76.2 Other mucopolysaccharidoses	0.018	0.981	0.000
E76.1 Mucopolysaccharidosis, type II	0.018	0.981	0.000
E76.0 Mucopolysaccharidosis, type I	0.018	0.981	0.000
Q05 Spina bifida	0.018	0.982	0.000
E14.9 Without complications	0.018	0.982	0.000
F05.9 Delirium, unspecified	0.018	0.982	0.000
Q05.9 Spina bifida, unspecified	0.018	0.982	0.000
E84.8 Cystic fibrosis with other manifestations	0.018	0.982	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.018	0.982	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.018	0.982	0.000
E75.6 Lipid storage disorder, unspecified	0.017	0.982	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.017	0.982	0.000
E75.3 Sphingolipidosis, unspecified	0.017	0.982	0.000
E75.2 Other sphingolipidosis	0.017	0.982	0.000
E75.1 Other gangliosidosis	0.017	0.982	0.000
E75.0 GM2 gangliosidosis	0.017	0.982	0.000
Q07 Other congenital malformations of nervous system	0.018	0.982	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.017	0.983	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.017	0.983	0.000
E84.9 Cystic fibrosis, unspecified	0.016	0.983	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.017	0.983	0.000
Q07.0 Arnold-Chiari syndrome	0.016	0.983	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.016	0.984	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.016	0.984	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.016	0.984	0.000
E74.2 Disorders of galactose metabolism	0.016	0.984	0.000
E74.1 Disorders of fructose metabolism	0.016	0.984	0.000
E74.0 Glycogen storage disease	0.016	0.984	0.000
E75.5 Other lipid storage disorders	0.016	0.984	0.000
E73.8 Other lactose intolerance	0.016	0.984	0.000
E73.1 Secondary lactase deficiency	0.016	0.984	0.000
E73.0 Congenital lactase deficiency	0.016	0.984	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.016	0.984	0.000
E23.6 Other disorders of pituitary gland	0.015	0.984	0.001
F03 Unspecified dementia	0.016	0.984	0.000
F05.0 Delirium not superimposed on dementia, so described	0.016	0.984	0.000
G60.3 Idiopathic progressive neuropathy	0.015	0.984	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.015	0.984	0.000
G60.1 Refsum's disease	0.015	0.984	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.016	0.984	0.000
Q04 Other congenital malformations of brain	0.015	0.984	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.015	0.984	0.000
E87.4 Mixed disorder of acid-base balance	0.015	0.984	0.000
G61.0 Guillain-Barre syndrome	0.015	0.985	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.985	0.015
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.015	0.985	0.000
E87.7 Fluid overload	0.015	0.985	0.000
E07.1 Dyshormogenetic goitre	0.015	0.985	0.000
E07.0 Hypersecretion of calcitonin	0.015	0.985	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.985	0.015
E89.3 Postprocedural hypopituitarism	0.015	0.985	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.015	0.985	0.000
F09 Unspecified organic or symptomatic mental disorder	0.014	0.985	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.014	0.986	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.014	0.986	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.014	0.986	0.000
F01.1 Multi-infarct dementia	0.014	0.986	0.000
F22 Persistent delusional disorders	0.000	0.986	0.014
H36 Retinal disorders in diseases classified elsewhere	0.014	0.986	0.000
E85 Amyloidosis	0.014	0.986	0.000
F01.8 Other vascular dementia	0.014	0.986	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.014	0.986	0.000
F01.2 Subcortical vascular dementia	0.014	0.986	0.000
F01.0 Vascular dementia of acute onset	0.014	0.986	0.000
Q07.8 Other specified congenital malformations of nervous system	0.014	0.986	0.000
F05.1 Delirium superimposed on dementia	0.014	0.986	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.986	0.014
T43.2 Other and unspecified antidepressants	0.000	0.986	0.014
F05.8 Other delirium	0.014	0.986	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.014	0.986	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.014	0.986	0.000
S30.1 Contusion of abdominal wall	0.014	0.986	0.000
F00 Dementia in Alzheimer's disease	0.014	0.986	0.000
F25 Schizoaffective disorders	0.000	0.986	0.014
F22.0 Delusional disorder	0.000	0.986	0.014
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.014	0.986	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.014	0.986	0.000
Q06 Other congenital malformations of spinal cord	0.014	0.986	0.000
Q01 Encephalocele	0.014	0.986	0.000
Q00 Anencephaly and similar malformations	0.014	0.986	0.000
Q02 Microcephaly	0.014	0.986	0.000
Q35-Q37 Cleft lip and cleft palate	0.014	0.986	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.013	0.986	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.013	0.986	0.001
E06.3 Autoimmune thyroiditis	0.013	0.987	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.013	0.987	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.013	0.987	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.013	0.987	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.013	0.987	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.013	0.987	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.013	0.987	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.013	0.987	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.013	0.987	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.013	0.987	0.000
Q04.8 Other specified congenital malformations of brain	0.013	0.987	0.000
Q03 Congenital hydrocephalus	0.013	0.987	0.000
E86 Volume depletion	0.013	0.987	0.000
E73.9 Lactose intolerance, unspecified	0.013	0.987	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.013	0.987	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.013	0.987	0.000
E78.6 Lipoprotein deficiency	0.013	0.987	0.000
M35.0 Sicca syndrome [Sjogren]	0.013	0.987	0.000
F02 Dementia in other diseases classified elsewhere	0.012	0.987	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.013	0.987	0.000
F07.2 Postconcussional syndrome	0.012	0.987	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.988	0.012
Q40 Other congenital malformations of upper alimentary tract	0.012	0.988	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.012	0.988	0.000
F07.0 Organic personality disorder	0.012	0.988	0.000
G60.0 Hereditary motor and sensory neuropathy	0.012	0.988	0.000
Q80-Q89 Other congenital malformations	0.012	0.988	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.988	0.012
E88 Other metabolic disorders	0.012	0.988	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.012	0.988	0.000
Q04.6 Congenital cerebral cysts	0.012	0.988	0.000
Q35 Cleft palate	0.012	0.988	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.012	0.988	0.000
Q27 Other congenital malformations of peripheral vascular system	0.012	0.988	0.000
F25.0 Schizoaffective disorder, manic type	0.000	0.988	0.012
E03 Other hypothyroidism	0.012	0.988	0.000
Q18 Other congenital malformations of face and neck	0.012	0.988	0.000
Q96 Turner's syndrome	0.011	0.988	0.000
E78.5 Hyperlipidaemia, unspecified	0.012	0.988	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.011	0.988	0.000
E07.8 Other specified disorders of thyroid	0.011	0.988	0.000
E78.2 Mixed hyperlipidaemia	0.011	0.989	0.000
Q50-Q56 Congenital malformations of genital organs	0.011	0.989	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.011	0.989	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.011	0.989	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.011	0.989	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.011	0.989	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.011	0.989	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.011	0.989	0.000
G63.1 Polyneuropathy in neoplastic disease	0.011	0.989	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.011	0.989	0.000
Q27.3 Peripheral arteriovenous malformation	0.011	0.989	0.000
Q04.9 Congenital malformation of brain, unspecified	0.011	0.989	0.000
Q04.5 Megalencephaly	0.011	0.989	0.000
Q04.4 Septo-optic dysplasia	0.011	0.989	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations