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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2261566
log Bayes Factor = 80.4992
Chromosome 6   position 32,754,081  (GRCh37) Explore rs2261566 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
D00-D09 In situ neoplasms
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
D04 Carcinoma in situ of skin
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.001 0.999
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.001 0.999
E11.9 Without complications
0.000 0.001 0.999
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
G37 Other demyelinating diseases of central nervous system
0.997 0.003 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.005 0.995
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.005 0.995
G37.9 Demyelinating disease of central nervous system, unspecified
0.995 0.005 0.000
L57.0 Actinic keratosis
0.000 0.006 0.994
C44 Other malignant neoplasms of skin
0.000 0.007 0.993
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.007 0.993
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.007 0.993
Chapter II Neoplasms
0.000 0.007 0.993
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.009 0.991
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.009 0.991
C44.7 Skin of lower limb, including hip
0.000 0.011 0.989
E70-E90 Metabolic disorders
0.000 0.012 0.988
L40.5 Arthropathic psoriasis
0.000 0.013 0.987
C44.6 Skin of upper limb, including shoulder
0.000 0.014 0.986
H36.0 Diabetic retinopathy
0.000 0.019 0.981
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.020 0.980
L40 Psoriasis
0.000 0.022 0.978
D04.5 Skin of trunk
0.000 0.022 0.978
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.022 0.978
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.023 0.977
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.023 0.977
D04.7 Skin of lower limb, including hip
0.000 0.024 0.976
D06 Carcinoma in situ of cervix uteri
0.000 0.025 0.975
C83.3 Large cell (diffuse)
0.000 0.029 0.971
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.030 0.970
E10.1 With ketoacidosis
0.000 0.038 0.962
E89.0 Postprocedural hypothyroidism
0.000 0.040 0.960
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.042 0.958
D06.9 Cervix, unspecified
0.000 0.043 0.957
E10.5 With peripheral circulatory complications
0.000 0.049 0.951
L40.9 Psoriasis, unspecified
0.000 0.050 0.950
E83.1 Disorders of iron metabolism
0.948 0.052 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.054 0.946
M06.0 Seronegative rheumatoid arthritis
0.000 0.059 0.941
L40-L45 Papulosquamous disorders
0.000 0.062 0.938
C44.3 Skin of other and unspecified parts of face
0.000 0.062 0.938
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.068 0.932
D09 Carcinoma in situ of other and unspecified sites
0.000 0.070 0.930
D04.3 Skin of other and unspecified parts of face
0.000 0.075 0.925
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.082 0.918
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.085 0.915
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.091 0.909
M06.3 Rheumatoid nodule
0.000 0.092 0.908
E20-E35 Disorders of other endocrine glands
0.000 0.095 0.905
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.102 0.898
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.106 0.894
E10.0 With coma
0.000 0.111 0.889
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.111 0.889
H36 Retinal disorders in diseases classified elsewhere
0.000 0.112 0.888
E10.4 With neurological complications
0.000 0.117 0.883
C91 Lymphoid leukaemia
0.000 0.120 0.880
G37.8 Other specified demyelinating diseases of central nervous system
0.878 0.122 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.122 0.878
D04.4 Skin of scalp and neck
0.000 0.123 0.877
C85.1 B-cell lymphoma, unspecified
0.000 0.125 0.875
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.130 0.870
E10.2 With renal complications
0.000 0.131 0.869
E78.6 Lipoprotein deficiency
0.000 0.133 0.867
E27 Other disorders of adrenal gland
0.000 0.136 0.864
D09.0 Bladder
0.000 0.139 0.861
D03 Melanoma in situ
0.000 0.146 0.854
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.853 0.147 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.154 0.846
C82.2 Large cell, follicular
0.000 0.161 0.838
E10.8 With unspecified complications
0.000 0.164 0.836
C82.0 Small cleaved cell, follicular
0.000 0.165 0.835
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.167 0.833
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.169 0.831
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.172 0.828
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.174 0.826
E11.5 With peripheral circulatory complications
0.000 0.175 0.825
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.179 0.821
H30-H36 Disorders of choroid and retina
0.000 0.179 0.821
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.181 0.819
E88 Other metabolic disorders
0.000 0.183 0.817
D04.9 Skin, unspecified
0.000 0.184 0.816
E16 Other disorders of pancreatic internal secretion
0.000 0.190 0.810
E78.2 Mixed hyperlipidaemia
0.000 0.191 0.809
E23 Hypofunction and other disorders of pituitary gland
0.000 0.192 0.808
H35 Other retinal disorders
0.000 0.193 0.807
E78.5 Hyperlipidaemia, unspecified
0.000 0.194 0.806
E10.6 With other specified complications
0.000 0.199 0.801
E11.1 With ketoacidosis
0.000 0.201 0.799
C43 Malignant melanoma of skin
0.000 0.205 0.795
E89.3 Postprocedural hypopituitarism
0.000 0.208 0.792
# Top node
0.000 0.209 0.791
L40.1 Generalised pustular psoriasis
0.000 0.209 0.791
E89.2 Postprocedural hypoparathyroidism
0.000 0.211 0.789
E89.4 Postprocedural ovarian failure
0.000 0.213 0.787
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.214 0.786
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.214 0.786
E11.0 With coma
0.000 0.216 0.784
E06 Thyroiditis
0.000 0.222 0.778
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.225 0.775
C44.0 Skin of lip
0.000 0.226 0.774
C91.9 Lymphoid leukaemia, unspecified
0.000 0.228 0.772
C44.4 Skin of scalp and neck
0.000 0.228 0.772
E79 Disorders of purine and pyrimidine metabolism
0.000 0.229 0.771
H35.8 Other specified retinal disorders
0.000 0.229 0.771
G36 Other acute disseminated demyelination
0.769 0.231 0.000
C83.1 Small cleaved cell (diffuse)
0.000 0.233 0.767
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.234 0.766
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.234 0.766
H35.6 Retinal haemorrhage
0.000 0.235 0.765
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.236 0.764
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.240 0.760
E13 Other specified diabetes mellitus
0.000 0.243 0.757
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.245 0.755
D03.5 Melanoma in situ of trunk
0.000 0.246 0.754
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.247 0.753
D04.2 Skin of ear and external auricular canal
0.000 0.248 0.752
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.249 0.751
M06.4 Inflammatory polyarthropathy
0.000 0.249 0.751
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.251 0.749
M06.34 Rheumatoid nodule (Hand)
0.000 0.252 0.748
E78.1 Pure hyperglyceridaemia
0.000 0.254 0.746
D09.1 Other and unspecified urinary organs
0.000 0.256 0.744
C73 Malignant neoplasm of thyroid gland
0.000 0.256 0.744
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.260 0.740
Chapter VII Diseases of the eye and adnexa
0.000 0.260 0.740
C83.7 Burkitt's tumour
0.000 0.261 0.739
L42 Pityriasis rosea
0.000 0.262 0.738
E70 Disorders of aromatic amino-acid metabolism
0.000 0.267 0.733
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.267 0.733
E28 Ovarian dysfunction
0.000 0.268 0.732
H35.2 Other proliferative retinopathy
0.000 0.268 0.732
M06.8 Other specified rheumatoid arthritis
0.000 0.271 0.729
E05.8 Other thyrotoxicosis
0.000 0.271 0.729
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.271 0.729
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.271 0.728
E84 Cystic fibrosis
0.000 0.274 0.726
L43 Lichen planus
0.000 0.275 0.725
E23.7 Disorder of pituitary gland, unspecified
0.000 0.276 0.724
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.276 0.724
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.278 0.721
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.279 0.721
E11.2 With renal complications
0.000 0.281 0.719
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.717
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.717
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.283 0.717
D04.8 Skin of other sites
0.000 0.283 0.716
D04.0 Skin of lip
0.000 0.283 0.716
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.284 0.716
D04.6 Skin of upper limb, including shoulder
0.000 0.285 0.715
G37.5 Concentric sclerosis [Balo]
0.715 0.285 0.000
G37.4 Subacute necrotising myelitis
0.715 0.285 0.000
G37.2 Central pontine myelinolysis
0.715 0.285 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.285 0.000
G37.0 Diffuse sclerosis
0.715 0.285 0.000
C91.5 Adult T-cell leukaemia
0.000 0.286 0.713
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.287 0.713
C44.8 Overlapping lesion of skin
0.000 0.288 0.712
M10 Gout
0.000 0.288 0.712
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.288 0.712
C85.0 Lymphosarcoma
0.000 0.288 0.712
D06.0 Endocervix
0.000 0.288 0.712
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.290 0.709
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.291 0.709
C91.0 Acute lymphoblastic leukaemia
0.000 0.291 0.709
E77 Disorders of glycoprotein metabolism
0.000 0.292 0.708
E76 Disorders of glycosaminoglycan metabolism
0.000 0.292 0.708
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.292 0.708
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.292 0.708
E06.3 Autoimmune thyroiditis
0.000 0.293 0.707
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.293 0.707
E23.6 Other disorders of pituitary gland
0.000 0.295 0.705
E03.1 Congenital hypothyroidism without goitre
0.000 0.297 0.703
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.297 0.702
E89.5 Postprocedural testicular hypofunction
0.000 0.297 0.702
C88 Malignant immunoproliferative diseases
0.000 0.297 0.702
L40.3 Pustulosis palmaris et plantaris
0.000 0.298 0.701
L40.2 Acrodermatitis continua
0.000 0.298 0.701
C82.6 Cutaneous follicle centre lymphoma
0.000 0.299 0.701
C82.5 Diffuse follicle centre lymphoma
0.000 0.299 0.701
C82.4 Follicular lymphoma grade IIIb
0.000 0.299 0.701
L40.4 Guttate psoriasis
0.000 0.299 0.700
C83.6 Undifferentiated (diffuse)
0.000 0.300 0.700
C83.5 Lymphoblastic (diffuse)
0.000 0.300 0.700
C83.4 Immunoblastic (diffuse)
0.000 0.300 0.700
C83.2 Mixed small and large cell (diffuse)
0.000 0.300 0.700
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.300 0.700
D06.7 Other parts of cervix
0.000 0.301 0.699
D06.1 Exocervix
0.000 0.301 0.699
C86 Other specified types of T/NK-cell lymphoma
0.000 0.306 0.694
M11 Other crystal arthropathies
0.000 0.308 0.692
E88.8 Other specified metabolic disorders
0.000 0.309 0.691
H30 Chorioretinal inflammation
0.000 0.314 0.686
E89.1 Postprocedural hypoinsulinaemia
0.000 0.314 0.686
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.319 0.681
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.323 0.677
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.325 0.675
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.325 0.675
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.325 0.675
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.325 0.675
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.325 0.675
E11.8 With unspecified complications
0.000 0.326 0.674
D07.2 Vagina
0.000 0.326 0.674
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.327 0.673
L44 Other papulosquamous disorders
0.000 0.327 0.673
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.327 0.673
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.328 0.672
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.328 0.672
C94 Other leukaemias of specified cell type
0.000 0.328 0.672
C12 Malignant neoplasm of pyriform sinus
0.000 0.330 0.670
M12 Other specific arthropathies
0.000 0.330 0.670
D03.2 Melanoma in situ of ear and external auricular canal
0.000 0.330 0.670
L57.5 Actinic granuloma
0.000 0.332 0.668
L57.3 Poikiloderma of Civatte
0.000 0.332 0.668
L57.2 Cutis rhomboidalis nuchae
0.000 0.332 0.668
L57.1 Actinic reticuloid
0.000 0.332 0.668
D09.9 Carcinoma in situ, unspecified
0.000 0.333 0.667
D09.7 Carcinoma in situ of other specified sites
0.000 0.333 0.667
D09.3 Thyroid and other endocrine glands
0.000 0.333 0.667
D09.2 Eye
0.000 0.333 0.667
E16.1 Other hypoglycaemia
0.000 0.333 0.667
C82.3 Follicular lymphoma grade IIIa
0.000 0.340 0.660
D00.1 Oesophagus
0.000 0.341 0.659
E88.9 Metabolic disorder, unspecified
0.000 0.342 0.658
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.342 0.658
L41 Parapsoriasis
0.000 0.343 0.656
C93 Monocytic leukaemia
0.000 0.345 0.655
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.346 0.654
E29 Testicular dysfunction
0.000 0.347 0.653
L55 Sunburn
0.000 0.348 0.652
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.349 0.651
M06.38 Rheumatoid nodule (Other)
0.000 0.349 0.651
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.349 0.651
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.349 0.651
M06.33 Rheumatoid nodule (Forearm)
0.000 0.349 0.651
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.349 0.651
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.350 0.650
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.351 0.649
E32 Diseases of thymus
0.000 0.351 0.649
E31 Polyglandular dysfunction
0.000 0.351 0.649
E30 Disorders of puberty, not elsewhere classified
0.000 0.351 0.649
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.352 0.648
D04.1 Skin of eyelid, including canthus
0.000 0.352 0.647
E03.8 Other specified hypothyroidism
0.000 0.355 0.645
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.356 0.644
C91.4 Hairy-cell leukaemia
0.000 0.356 0.644
D03.3 Melanoma in situ of other and unspecified parts of face
0.000 0.360 0.640
L40.0 Psoriasis vulgaris
0.000 0.362 0.638
E15 Nondiabetic hypoglycaemic coma
0.000 0.362 0.637
H53-H54 Visual disturbances and blindness
0.000 0.362 0.637
D03.4 Melanoma in situ of scalp and neck
0.000 0.363 0.637
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.363 0.636
M05.2 Rheumatoid vasculitis
0.000 0.364 0.636
E85 Amyloidosis
0.000 0.364 0.636
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.366 0.634
D07.4 Penis
0.000 0.367 0.633
D02.0 Larynx
0.000 0.367 0.632
D00.0 Lip, oral cavity and pharynx
0.000 0.368 0.632
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.369 0.631
C91.7 Other lymphoid leukaemia
0.000 0.369 0.631
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.369 0.631
C91.3 Prolymphocytic leukaemia
0.000 0.369 0.631
C91.2 Subacute lymphocytic leukaemia
0.000 0.369 0.631
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.370 0.630
H35.0 Background retinopathy and retinal vascular changes
0.000 0.372 0.628
E20 Hypoparathyroidism
0.000 0.373 0.627
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.375 0.625
E73 Lactose intolerance
0.000 0.375 0.625
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.375 0.625
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.380 0.620
E27.5 Adrenomedullary hyperfunction
0.000 0.381 0.619
E27.0 Other adrenocortical overactivity
0.000 0.381 0.619
E83 Disorders of mineral metabolism
0.041 0.381 0.577
E24 Cushing's syndrome
0.000 0.381 0.619
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.382 0.618
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.384 0.616
H53 Visual disturbances
0.000 0.385 0.615
L58 Radiodermatitis
0.000 0.385 0.615
E78.8 Other disorders of lipoprotein metabolism
0.000 0.386 0.614
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.387 0.613
C95 Leukaemia of unspecified cell type
0.000 0.387 0.612
D03.9 Melanoma in situ, unspecified
0.000 0.388 0.612
D03.8 Melanoma in situ of other sites
0.000 0.388 0.612
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.392 0.607
G36.0 Neuromyelitis optica [Devic]
0.606 0.394 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.394 0.606
D03.7 Melanoma in situ of lower limb, including hip
0.000 0.394 0.606
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.395 0.605
M14 Arthropathies in other diseases classified elsewhere
0.000 0.395 0.605
E65-E68 Obesity and other hyperalimentation
0.000 0.396 0.604
E26 Hyperaldosteronism
0.000 0.397 0.603
L43.8 Other lichen planus
0.000 0.397 0.602
E88.3 Tumour lysis syndrome
0.000 0.398 0.602
E11.6 With other specified complications
0.000 0.399 0.601
E78.3 Hyperchylomicronaemia
0.000 0.400 0.600
L57.4 Cutis laxa senilis
0.000 0.401 0.598
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.403 0.597
C03 Malignant neoplasm of gum
0.000 0.404 0.596
E25 Adrenogenital disorders
0.000 0.404 0.595
D03.0 Melanoma in situ of lip
0.000 0.406 0.593
E28.2 Polycystic ovarian syndrome
0.000 0.410 0.590
D07.1 Vulva
0.000 0.410 0.590
H30.9 Chorioretinal inflammation, unspecified
0.000 0.410 0.590
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.411 0.589
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.412 0.588
D00.2 Stomach
0.000 0.413 0.587
H53.1 Subjective visual disturbances
0.000 0.413 0.587
E23.2 Diabetes insipidus
0.000 0.415 0.585
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.415 0.585
D01.0 Colon
0.000 0.416 0.584
E13.9 Without complications
0.000 0.417 0.583
E72 Other disorders of amino-acid metabolism
0.000 0.418 0.582
Q80-Q89 Other congenital malformations
0.000 0.418 0.582
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.419 0.581
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.419 0.580
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.419 0.580
E16.4 Abnormal secretion of gastrin
0.000 0.419 0.580
E16.3 Increased secretion of glucagon
0.000 0.419 0.580
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.420 0.580
E88.2 Lipomatosis, not elsewhere classified
0.000 0.420 0.580
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.420 0.580
E23.1 Drug-induced hypopituitarism
0.000 0.420 0.580
C13 Malignant neoplasm of hypopharynx
0.000 0.421 0.579
H35.1 Retinopathy of prematurity
0.000 0.421 0.579
M13 Other arthritis
0.000 0.421 0.579
C44.2 Skin of ear and external auricular canal
0.000 0.423 0.577
E07 Other disorders of thyroid
0.000 0.423 0.577
E80.1 Porphyria cutanea tarda
0.000 0.425 0.575
E16.2 Hypoglycaemia, unspecified
0.000 0.425 0.575
Q85 Phakomatoses, not elsewhere classified
0.000 0.427 0.573
E40-E46 Malnutrition
0.000 0.427 0.573
C11 Malignant neoplasm of nasopharynx
0.000 0.428 0.572
E27.9 Disorder of adrenal gland, unspecified
0.000 0.428 0.572
E06.5 Other chronic thyroiditis
0.000 0.428 0.572
M10.0 Idiopathic gout
0.000 0.428 0.572
C43.8 Overlapping malignant melanoma of skin
0.000 0.430 0.570
C43.0 Malignant melanoma of lip
0.000 0.430 0.570
E27.8 Other specified disorders of adrenal gland
0.000 0.430 0.570
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.433 0.567
C07 Malignant neoplasm of parotid gland
0.000 0.433 0.567
D03.1 Melanoma in situ of eyelid, including canthus
0.000 0.433 0.567
M11.9 Crystal arthropathy, unspecified
0.000 0.436 0.564
C74 Malignant neoplasm of adrenal gland
0.000 0.436 0.563
D02.4 Respiratory system, unspecified
0.000 0.437 0.563
D02.3 Other parts of respiratory system
0.000 0.437 0.563
D02.2 Bronchus and lung
0.000 0.437 0.563
D02.1 Trachea
0.000 0.437 0.563
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.437 0.563
D01.3 Anus and anal canal
0.000 0.439 0.561
E06.4 Drug-induced thyroiditis
0.000 0.442 0.557
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.442 0.557
E06.0 Acute thyroiditis
0.000 0.442 0.557
E80.4 Gilbert's syndrome
0.000 0.443 0.557
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.445 0.555
C81 Hodgkin's disease
0.000 0.446 0.554
L10-L14 Bullous disorders
0.000 0.446 0.554
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.447 0.553
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.447 0.553
E79.1 Lesch-Nyhan syndrome
0.000 0.447 0.553
E28.3 Primary ovarian failure
0.000 0.448 0.552
G36.9 Acute disseminated demyelination, unspecified
0.551 0.448 0.000
G36.8 Other specified acute disseminated demyelination
0.551 0.448 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.551 0.448 0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.449 0.551
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.449 0.551
E70.3 Albinism
0.000 0.449 0.551
D07.6 Other and unspecified male genital organs
0.000 0.451 0.549
D07.3 Other and unspecified female genital organs
0.000 0.451 0.549
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.454 0.546
E13.8 With unspecified complications
0.000 0.457 0.543
E13.7 With multiple complications
0.000 0.457 0.543
E13.6 With other specified complications
0.000 0.457 0.543
E13.5 With peripheral circulatory complications
0.000 0.457 0.543
E13.4 With neurological complications
0.000 0.457 0.543
E13.3 With ophthalmic complications
0.000 0.457 0.543
E13.2 With renal complications
0.000 0.457 0.543
E13.1 With ketoacidosis
0.000 0.457 0.543
E13.0 With coma
0.000 0.457 0.543
C05 Malignant neoplasm of palate
0.000 0.458 0.542
Q85.8 Other phakomatoses, not elsewhere classified
0.000 0.458 0.542
C02.9 Tongue, unspecified
0.000 0.459 0.541
D03.6 Melanoma in situ of upper limb, including shoulder
0.000 0.461 0.539
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.461 0.538
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.461 0.538
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.461 0.538
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.461 0.538
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.461 0.538
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.461 0.538
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.461 0.538
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.461 0.538
H53.9 Visual disturbance, unspecified
0.000 0.462 0.538
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.462 0.538
E84.9 Cystic fibrosis, unspecified
0.000 0.462 0.538
E14 Unspecified diabetes mellitus
0.000 0.466 0.534
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.469 0.531
H35.5 Hereditary retinal dystrophy
0.000 0.469 0.531
D01.9 Digestive organ, unspecified
0.000 0.469 0.531
D01.7 Other specified digestive organs
0.000 0.469 0.531
D01.5 Liver, gallbladder and bile ducts
0.000 0.469 0.531
D01.4 Other and unspecified parts of intestine
0.000 0.469 0.531
D01.1 Rectosigmoid junction
0.000 0.469 0.531
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.470 0.530
H53.4 Visual field defects
0.000 0.470 0.530
H35.3 Degeneration of macula and posterior pole
0.000 0.471 0.529
Q85.9 Phakomatosis, unspecified
0.000 0.474 0.526
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.474 0.526
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.474 0.526
E70.2 Disorders of tyrosine metabolism
0.000 0.474 0.526
E70.1 Other hyperphenylalaninaemias
0.000 0.474 0.526
E70.0 Classical phenylketonuria
0.000 0.474 0.526
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.474 0.525
E80.5 Crigler-Najjar syndrome
0.000 0.474 0.525
E80.3 Defects of catalase and peroxydase
0.000 0.474 0.525
E80.0 Hereditary erythropoietic porphyria
0.000 0.474 0.525
E28.9 Ovarian dysfunction, unspecified
0.000 0.475 0.525
E28.8 Other ovarian dysfunction
0.000 0.475 0.525
E28.1 Androgen excess
0.000 0.475 0.525
E28.0 Oestrogen excess
0.000 0.475 0.525
H43-H45 Disorders of vitreous body and globe
0.000 0.476 0.524
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.477 0.523
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.477 0.523
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.477 0.523
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.477 0.523
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.477 0.523
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.477 0.523
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.477 0.523
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.477 0.523
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.477 0.522
E84.8 Cystic fibrosis with other manifestations
0.000 0.480 0.520
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.480 0.520
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.480 0.520
Q83 Congenital malformations of breast
0.000 0.480 0.520
L43.3 Subacute (active) lichen planus
0.000 0.480 0.520
L43.2 Lichenoid drug reaction
0.000 0.480 0.520
L43.1 Bullous lichen planus
0.000 0.480 0.520
L43.0 Hypertrophic lichen planus
0.000 0.480 0.520
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.482 0.518
H53.2 Diplopia
0.000 0.484 0.516
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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