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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2267644
log Bayes Factor = 19.8415
Chromosome 6   position 32,192,560  (GRCh37) Explore rs2267644 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.997 0.003 0.000
H36.0 Diabetic retinopathy
0.996 0.004 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.995 0.005 0.000
H36 Retinal disorders in diseases classified elsewhere
0.994 0.006 0.000
H30-H36 Disorders of choroid and retina
0.992 0.008 0.000
Chapter VII Diseases of the eye and adnexa
0.990 0.010 0.000
E10.1 With ketoacidosis
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.987 0.013 0.000
Chapter XX External causes of morbidity and mortality
0.981 0.019 0.000
E14 Unspecified diabetes mellitus
0.977 0.023 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.974 0.026 0.000
E11 Non-insulin-dependent diabetes mellitus
0.965 0.035 0.000
E10.4 With neurological complications
0.963 0.037 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.962 0.038 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.959 0.041 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.944 0.056 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.940 0.060 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.920 0.080 0.000
Chapter VIII Diseases of the ear and mastoid process
0.912 0.088 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.908 0.092 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.908 0.092 0.000
E14.9 Without complications
0.894 0.106 0.000
E10.2 With renal complications
0.890 0.110 0.000
E14.3 With ophthalmic complications
0.885 0.115 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.883 0.117 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.882 0.118 0.000
L05 Pilonidal cyst
0.881 0.119 0.000
V10-V19 Pedal cyclist injured in transport accident
0.878 0.122 0.000
Chapter VI Diseases of the nervous system
0.872 0.128 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.867 0.133 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.865 0.135 0.000
M86-M90 Other osteopathies
0.864 0.136 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.863 0.137 0.000
M40-M43 Deforming dorsopathies
0.862 0.138 0.000
H33 Retinal detachments and breaks
0.857 0.143 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.855 0.145 0.000
Chapter I Certain infectious and parasitic diseases
0.853 0.147 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.850 0.150 0.000
S50-S59 Injuries to the elbow and forearm
0.850 0.150 0.000
E10.5 With peripheral circulatory complications
0.847 0.152 0.000
X60-X84 Intentional self-harm
0.847 0.153 0.000
E11.3 With ophthalmic complications
0.847 0.153 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.846 0.154 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.843 0.157 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.841 0.159 0.000
E10.0 With coma
0.840 0.160 0.000
L03 Cellulitis
0.839 0.161 0.000
H65-H75 Diseases of middle ear and mastoid
0.833 0.167 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.832 0.168 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.831 0.169 0.000
M06.3 Rheumatoid nodule
0.822 0.178 0.000
Y42.5 Other oestrogens and progestogens
0.821 0.179 0.000
M65-M68 Disorders of synovium and tendon
0.821 0.179 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.821 0.179 0.000
E11.5 With peripheral circulatory complications
0.816 0.184 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.812 0.188 0.000
E14.6 With other specified complications
0.811 0.189 0.000
E10.8 With unspecified complications
0.811 0.189 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.810 0.190 0.000
E11.0 With coma
0.809 0.191 0.000
H60-H62 Diseases of external ear
0.806 0.194 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.804 0.196 0.000
T43.2 Other and unspecified antidepressants
0.802 0.197 0.000
E70-E90 Metabolic disorders
0.802 0.198 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.801 0.199 0.000
E10.6 With other specified complications
0.801 0.199 0.000
E11.4 With neurological complications
0.800 0.200 0.000
A30-A49 Other bacterial diseases
0.797 0.203 0.000
S52 Fracture of forearm
0.795 0.205 0.000
L05.9 Pilonidal cyst without abscess
0.791 0.209 0.000
H31 Other disorders of choroid
0.790 0.210 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.789 0.211 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.788 0.212 0.000
Chapter XXII Codes for special purposes
0.786 0.214 0.000
M05 Seropositive rheumatoid arthritis
0.785 0.215 0.000
S10-S19 Injuries to the neck
0.784 0.216 0.000
H53-H54 Visual disturbances and blindness
0.782 0.218 0.000
G90-G99 Other disorders of the nervous system
0.782 0.218 0.000
M14 Arthropathies in other diseases classified elsewhere
0.779 0.221 0.000
V98-V99 Other and unspecified transport accidents
0.777 0.223 0.000
E11.6 With other specified complications
0.776 0.224 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.775 0.225 0.000
M60-M63 Disorders of muscles
0.771 0.229 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.769 0.231 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.766 0.234 0.000
H66 Suppurative and unspecified otitis media
0.766 0.234 0.000
Y44 Agents primarily affecting blood constituents
0.766 0.234 0.000
Y95 Nosocomial condition
0.764 0.236 0.000
L03.0 Cellulitis of finger and toe
0.762 0.238 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.762 0.238 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.759 0.241 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.759 0.241 0.000
A80-A89 Viral infections of the central nervous system
0.757 0.243 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.754 0.246 0.000
T79-T79 Certain early complications of trauma
0.752 0.248 0.000
H60 Otitis externa
0.752 0.248 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.751 0.249 0.000
M06.4 Inflammatory polyarthropathy
0.749 0.251 0.000
H33.2 Serous retinal detachment
0.748 0.252 0.000
E11.1 With ketoacidosis
0.747 0.253 0.000
S90-S99 Injuries to the ankle and foot
0.747 0.253 0.000
V18.0 Driver injured in nontraffic accident
0.747 0.253 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.740 0.260 0.000
S52.1 Fracture of upper end of radius
0.736 0.264 0.000
S40-S49 Injuries to the shoulder and upper arm
0.734 0.266 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.731 0.269 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.728 0.272 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.727 0.273 0.000
L05.0 Pilonidal cyst with abscess
0.727 0.273 0.000
Y52 Agents primarily affecting the cardiovascular system
0.725 0.274 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.725 0.275 0.000
G82 Paraplegia and tetraplegia
0.724 0.276 0.000
T91 Sequelae of injuries of neck and trunk
0.723 0.277 0.000
H54 Blindness and low vision
0.722 0.278 0.000
A49 Bacterial infection of unspecified site
0.719 0.281 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.719 0.281 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.718 0.282 0.000
E40-E46 Malnutrition
0.717 0.282 0.000
L08 Other local infections of skin and subcutaneous tissue
0.717 0.283 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M07 Psoriatic and enteropathic arthropathies
0.716 0.284 0.000
Q50-Q56 Congenital malformations of genital organs
0.715 0.284 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.715 0.285 0.000
Q38.7 Pharyngeal pouch
0.714 0.286 0.000
L03.3 Cellulitis of trunk
0.714 0.286 0.000
M06.0 Seronegative rheumatoid arthritis
0.713 0.287 0.000
E11.2 With renal complications
0.713 0.287 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.712 0.288 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.712 0.288 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.711 0.289 0.000
H30 Chorioretinal inflammation
0.711 0.289 0.000
H33.5 Other retinal detachments
0.710 0.289 0.000
T42.4 Benzodiazepines
0.710 0.290 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.710 0.290 0.000
T33-T35 Frostbite
0.708 0.292 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.708 0.292 0.000
T00-T07 Injuries involving multiple body regions
0.708 0.292 0.000
H33.4 Traction detachment of retina
0.707 0.293 0.000
X20-X29 Contact with venomous animals and plants
0.706 0.294 0.000
M80-M85 Disorders of bone density and structure
0.705 0.294 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.705 0.295 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.296 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.296 0.000
Y10-Y34 Event of undetermined intent
0.703 0.296 0.000
Y00-Y09 Assault
0.703 0.296 0.000
X85-X99 Assault
0.703 0.296 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.296 0.000
X50-X57 Overexertion, travel and privation
0.703 0.296 0.000
X30-X39 Exposure to forces of nature
0.703 0.296 0.000
X10-X19 Contact with heat and hot substances
0.703 0.296 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.296 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.296 0.000
W75-W84 Other accidental threats to breathing
0.703 0.296 0.000
W65-W74 Accidental drowning and submersion
0.703 0.296 0.000
W50-W64 Exposure to animate mechanical forces
0.703 0.296 0.000
V95-V97 Air and space transport accidents
0.703 0.296 0.000
V90-V94 Water transport accidents
0.703 0.296 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.296 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.296 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.296 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.296 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.296 0.000
X78 Intentional self-harm by sharp object
0.703 0.297 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.703 0.297 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.703 0.297 0.000
H55-H59 Other disorders of eye and adnexa
0.702 0.298 0.000
M87 Osteonecrosis
0.702 0.298 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.701 0.299 0.000
M40 Kyphosis and lordosis
0.701 0.299 0.000
E14.8 With unspecified complications
0.700 0.300 0.000
E14.7 With multiple complications
0.700 0.300 0.000
E14.5 With peripheral circulatory complications
0.700 0.300 0.000
E14.4 With neurological complications
0.700 0.300 0.000
E14.2 Withrenal complications
0.700 0.300 0.000
E14.1 With ketoacidosis
0.700 0.300 0.000
E14.0 With coma
0.700 0.300 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.700 0.300 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.699 0.301 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.699 0.301 0.000
Y88 Sequelae of surgical and medical care as external cause
0.698 0.302 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.698 0.302 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.698 0.302 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.698 0.302 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.698 0.302 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.698 0.302 0.000
T36 Poisoning by systemic antibiotics
0.698 0.302 0.000
M11 Other crystal arthropathies
0.698 0.302 0.000
M00-M03 Infectious arthropathies
0.697 0.302 0.000
V40-V49 Car occupant injured in transport accident
0.697 0.303 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.697 0.303 0.000
M41 Scoliosis
0.697 0.303 0.000
M06.34 Rheumatoid nodule (Hand)
0.695 0.305 0.000
Y85 Sequelae of transport accidents
0.693 0.307 0.000
S52.10 Fracture of upper end of radius (closed)
0.693 0.307 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.692 0.307 0.000
V20-V29 Motorcycle rider injured in transport accident
0.692 0.308 0.000
E11.8 With unspecified complications
0.692 0.308 0.000
E11.7 With multiple complications
0.692 0.308 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.692 0.308 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.691 0.309 0.000
L10-L14 Bullous disorders
0.690 0.310 0.000
L04 Acute lymphadenitis
0.688 0.312 0.000
L01 Impetigo
0.688 0.312 0.000
L00 Staphylococcal scalded skin syndrome
0.688 0.312 0.000
A87 Viral meningitis
0.688 0.312 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.686 0.314 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.683 0.317 0.000
H10-H13 Disorders of conjunctiva
0.683 0.317 0.000
G57 Mononeuropathies of lower limb
0.683 0.317 0.000
T98 Sequelae of other and unspecified effects of external causes
0.683 0.317 0.000
G70-G73 Diseases of myoneural junction and muscle
0.682 0.318 0.000
M90 Osteopathies in diseases classified elsewhere
0.679 0.321 0.000
M67 Other disorders of synovium and tendon
0.679 0.321 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.678 0.322 0.000
E13 Other specified diabetes mellitus
0.677 0.323 0.000
M13 Other arthritis
0.677 0.323 0.000
Y59 Other and unspecified vaccines and biological substances
0.676 0.323 0.000
Y58 Bacterial vaccines
0.676 0.323 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.676 0.323 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.676 0.323 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.676 0.323 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.676 0.323 0.000
Y48 Anaesthetics and therapeutic gases
0.676 0.323 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.676 0.323 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.676 0.323 0.000
Y57 Other and unspecified drugs and medicaments
0.676 0.324 0.000
G95 Other diseases of spinal cord
0.676 0.324 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.675 0.325 0.000
G82.2 Paraplegia, unspecified
0.675 0.325 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.674 0.326 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.674 0.326 0.000
H66.9 Otitis media, unspecified
0.674 0.326 0.000
T42.1 Iminostilbenes
0.672 0.328 0.000
Y40 Systemic antibiotics
0.670 0.330 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.670 0.330 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.668 0.332 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.667 0.332 0.000
H60.1 Cellulitis of external ear
0.667 0.333 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.667 0.333 0.000
H74 Other disorders of middle ear and mastoid
0.666 0.334 0.000
A41 Other septicaemia
0.666 0.334 0.000
H43-H45 Disorders of vitreous body and globe
0.665 0.334 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.664 0.336 0.000
S80-S89 Injuries to the knee and lower leg
0.663 0.337 0.000
E89.3 Postprocedural hypopituitarism
0.662 0.338 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.662 0.338 0.000
T85.2 Mechanical complication of intraocular lens
0.662 0.338 0.000
T43.9 Psychotropic drug, unspecified
0.660 0.340 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.660 0.340 0.000
T43.6 Psychostimulants with abuse potential
0.660 0.340 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.660 0.340 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.660 0.340 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.658 0.342 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.655 0.345 0.000
V80-V89 Other land transport accidents
0.655 0.345 0.000
H54.7 Unspecified visual loss
0.655 0.345 0.000
M89 Other disorders of bone
0.653 0.347 0.000
G56 Mononeuropathies of upper limb
0.653 0.347 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.652 0.348 0.000
H66.3 Other chronic suppurative otitis media
0.652 0.348 0.000
S20-S29 Injuries to the thorax
0.651 0.348 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.651 0.349 0.000
Q35-Q37 Cleft lip and cleft palate
0.651 0.349 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.651 0.349 0.000
H35 Other retinal disorders
0.651 0.349 0.000
M10 Gout
0.650 0.350 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.649 0.351 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.648 0.352 0.000
T14 Injury of unspecified body region
0.647 0.353 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.646 0.354 0.000
S70-S79 Injuries to the hip and thigh
0.645 0.355 0.000
S52.5 Fracture of lower end of radius
0.644 0.356 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.644 0.356 0.000
Q80-Q89 Other congenital malformations
0.643 0.357 0.000
G90 Disorders of autonomic nervous system
0.643 0.357 0.000
M43 Other deforming dorsopathies
0.642 0.358 0.000
T86 Failure and rejection of transplanted organs and tissues
0.641 0.359 0.000
T87 Complications peculiar to reattachment and amputation
0.641 0.359 0.000
G91 Hydrocephalus
0.640 0.360 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.640 0.360 0.000
Y49.2 Other and unspecified antidepressants
0.639 0.361 0.000
A87.9 Viral meningitis, unspecified
0.638 0.362 0.000
Y44.2 Anticoagulants
0.638 0.362 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.637 0.363 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.636 0.364 0.000
M88 Paget's disease of bone [osteitis deformans]
0.635 0.364 0.000
H90-H95 Other disorders of ear
0.635 0.365 0.000
G96 Other disorders of central nervous system
0.635 0.365 0.000
L03.8 Cellulitis of other sites
0.633 0.367 0.000
T92 Sequelae of injuries of upper limb
0.633 0.367 0.000
Y42.9 Other and unspecified hormone antagonists
0.632 0.368 0.000
Y42.4 Oral contraceptives
0.632 0.368 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.632 0.368 0.000
Y42.2 Antithyroid drugs
0.632 0.368 0.000
Y42.1 Thyroid hormones and substitutes
0.632 0.368 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.632 0.368 0.000
S12 Fracture of neck
0.632 0.368 0.000
S52.0 Fracture of upper end of ulna
0.632 0.368 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.631 0.369 0.000
V99 Unspecified transport accident
0.631 0.369 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.631 0.369 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.630 0.370 0.000
H31.8 Other specified disorders of choroid
0.630 0.370 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.629 0.371 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.629 0.371 0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle
0.629 0.371 0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle
0.629 0.371 0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus
0.629 0.371 0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van
0.629 0.371 0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle
0.629 0.371 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.629 0.371 0.000
V10 Pedal cyclist injured in collision with pedestrian or animal
0.629 0.371 0.000
H70 Mastoiditis and related conditions
0.627 0.373 0.000
T20 Burn and corrosion of head and neck
0.626 0.374 0.000
M86 Osteomyelitis
0.624 0.375 0.000
H60.8 Other otitis externa
0.624 0.376 0.000
A49.0 Staphylococcal infection, unspecified
0.624 0.376 0.000
S90 Superficial injury of ankle and foot
0.623 0.377 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.622 0.377 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.622 0.378 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.622 0.378 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.622 0.378 0.000
T42.3 Barbiturates
0.622 0.378 0.000
T42.2 Succinimides and oxazolidinediones
0.622 0.378 0.000
T42.0 Hydantoin derivatives
0.622 0.378 0.000
A40 Streptococcal septicaemia
0.622 0.378 0.000
M14.6 Neuropathic arthropathy
0.621 0.379 0.000
M66 Spontaneous rupture of synovium and tendon
0.620 0.380 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.620 0.380 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.618 0.382 0.000
E87.6 Hypokalaemia
0.618 0.382 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.618 0.382 0.000
M42 Spinal osteochondrosis
0.618 0.382 0.000
H69 Other disorders of Eustachian tube
0.616 0.384 0.000
T90 Sequelae of injuries of head
0.616 0.384 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.616 0.384 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.615 0.385 0.000
H33.1 Retinoschisis and retinal cysts
0.614 0.386 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.613 0.387 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.613 0.387 0.000
Y98 Lifestyle-related condition
0.613 0.387 0.000
Y97 Environmental-pollution-related condition
0.613 0.387 0.000
Y96 Work-related condition
0.613 0.387 0.000
G56.2 Lesion of ulnar nerve
0.612 0.388 0.000
B99-B99 Other infectious diseases
0.612 0.388 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.612 0.388 0.000
B65-B83 Helminthiases
0.612 0.388 0.000
B50-B64 Protozoal diseases
0.612 0.388 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.612 0.388 0.000
A75-A79 Rickettsioses
0.612 0.388 0.000
A70-A74 Other diseases caused by chlamydiae
0.612 0.388 0.000
A65-A69 Other spirochaetal diseases
0.612 0.388 0.000
A20-A28 Certain zoonotic bacterial diseases
0.612 0.388 0.000
A15-A19 Tuberculosis
0.612 0.388 0.000
H72 Perforation of tympanic membrane
0.610 0.390 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.610 0.390 0.000
T50.8 Diagnostic agents
0.610 0.390 0.000
T50.7 Analeptics and opioid receptor antagonists
0.610 0.390 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.610 0.390 0.000
T50.5 Appetite depressants
0.610 0.390 0.000
T50.4 Drugs affecting uric acid metabolism
0.610 0.390 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.610 0.390 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.610 0.390 0.000
T50.1 Loop [high-ceiling] diuretics
0.610 0.390 0.000
T50.0 Mineralocorticoids and their antagonists
0.610 0.390 0.000
E89.2 Postprocedural hypoparathyroidism
0.609 0.391 0.000
S59 Other and unspecified injuries of forearm
0.609 0.391 0.000
S58 Traumatic amputation of forearm
0.609 0.391 0.000
S57 Crushing injury of forearm
0.609 0.391 0.000
S56 Injury of muscle and tendon at forearm level
0.609 0.391 0.000
S55 Injury of blood vessels at forearm level
0.609 0.391 0.000
S54 Injury of nerves at forearm level
0.609 0.391 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.609 0.391 0.000
E87.7 Fluid overload
0.608 0.392 0.000
T66-T78 Other and unspecified effects of external causes
0.608 0.392 0.000
X84 Intentional self-harm by unspecified means
0.607 0.392 0.000
X83 Intentional self-harm by other specified means
0.607 0.392 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.607 0.392 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.607 0.392 0.000
X80 Intentional self-harm by jumping from a high place
0.607 0.392 0.000
X79 Intentional self-harm by blunt object
0.607 0.392 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.607 0.392 0.000
X76 Intentional self-harm by smoke, fire and flames
0.607 0.392 0.000
X75 Intentional self-harm by explosive material
0.607 0.392 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.607 0.392 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.607 0.392 0.000
X72 Intentional self-harm by handgun discharge
0.607 0.392 0.000
X71 Intentional self-harm by drowning and submersion
0.607 0.392 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.607 0.392 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.607 0.392 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.607 0.392 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.607 0.392 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.607 0.392 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.607 0.392 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.607 0.392 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.607 0.392 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.607 0.392 0.000
M62 Other disorders of muscle
0.607 0.393 0.000
T95 Sequelae of burns, corrosions and frostbite
0.607 0.393 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.607 0.393 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.607 0.393 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.605 0.395 0.000
S52.2 Fracture of shaft of ulna
0.604 0.396 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.603 0.396 0.000
E85 Amyloidosis
0.602 0.398 0.000
M67.1 Other contracture of tendon (sheath)
0.601 0.399 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.601 0.399 0.000
X78.0 Home
0.600 0.400 0.000
E88 Other metabolic disorders
0.599 0.401 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.599 0.401 0.000
Y43 Primarily systemic agents
0.599 0.401 0.000
Q00-Q07 Congenital malformations of the nervous system
0.597 0.402 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.597 0.402 0.000
H68 Eustachian salpingitis and obstruction
0.597 0.402 0.000
H67 Otitis media in diseases classified elsewhere
0.597 0.402 0.000
Y89 Sequelae of other external causes
0.596 0.404 0.000
H54.0 Blindness, both eyes
0.596 0.404 0.000
G54 Nerve root and plexus disorders
0.594 0.406 0.000
H65 Nonsuppurative otitis media
0.594 0.406 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.593 0.407 0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.593 0.407 0.000
M45-M49 Spondylopathies
0.591 0.409 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.589 0.411 0.000
M06.38 Rheumatoid nodule (Other)
0.589 0.411 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.589 0.411 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.589 0.411 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.589 0.411 0.000
M06.33 Rheumatoid nodule (Forearm)
0.589 0.411 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.589 0.411 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.589 0.411 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.589 0.411 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.589 0.411 0.000
H60.9 Otitis externa, unspecified
0.589 0.411 0.000
Q45 Other congenital malformations of digestive system
0.589 0.411 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.589 0.411 0.000
Q43 Other congenital malformations of intestine
0.589 0.411 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.589 0.411 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.589 0.411 0.000
Q40 Other congenital malformations of upper alimentary tract
0.589 0.411 0.000
Q39 Congenital malformations of oesophagus
0.589 0.411 0.000
T91.3 Sequelae of injury of spinal cord
0.589 0.411 0.000
D50-D53 Nutritional anaemias
0.589 0.411 0.000
Y85.0 Sequelae of motor-vehicle accident
0.588 0.412 0.000
T23 Burn and corrosion of wrist and hand
0.588 0.412 0.000
S52.7 Multiple fractures of forearm
0.588 0.412 0.000
H31.0 Chorioretinal scars
0.588 0.412 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.587 0.413 0.000
U80 Agent resistant to penicillin and related antibiotics
0.586 0.414 0.000
M40.2 Other and unspecified kyphosis
0.586 0.414 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.585 0.414 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.584 0.416 0.000
Q60-Q64 Congenital malformations of the urinary system
0.582 0.418 0.000
S89 Other and unspecified injuries of lower leg
0.581 0.418 0.000
M65 Synovitis and tenosynovitis
0.581 0.419 0.000
B15-B19 Viral hepatitis
0.581 0.419 0.000
M13.0 Polyarthritis, unspecified
0.580 0.420 0.000
H71 Cholesteatoma of middle ear
0.580 0.420 0.000
Chapter X Diseases of the respiratory system
0.579 0.421 0.000
A49.8 Other bacterial infections of unspecified site
0.579 0.421 0.000
M41.9 Scoliosis, unspecified
0.579 0.421 0.000
Q51 Congenital malformations of uterus and cervix
0.578 0.421 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.578 0.422 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.578 0.422 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.577 0.423 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.577 0.423 0.000
G95.1 Vascular myelopathies
0.577 0.423 0.000
G71 Primary disorders of muscles
0.576 0.423 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.576 0.424 0.000
V18.4 Driver injured in traffic accident
0.576 0.424 0.000
V18.5 Passenger injured in traffic accident
0.576 0.424 0.000
V18.3 Person injured while boarding or alighting
0.576 0.424 0.000
V18.1 Passenger injured in nontraffic accident
0.576 0.424 0.000
E84 Cystic fibrosis
0.575 0.425 0.000
E79 Disorders of purine and pyrimidine metabolism
0.575 0.425 0.000
E77 Disorders of glycoprotein metabolism
0.575 0.425 0.000
E76 Disorders of glycosaminoglycan metabolism
0.575 0.425 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.575 0.425 0.000
E74 Other disorders of carbohydrate metabolism
0.575 0.425 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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