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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2269429
log Bayes Factor = 15.4708
Chromosome 6   position 32,029,183  (GRCh37) Explore rs2269429 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.003 0.997
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.011 0.989
E11.3 With ophthalmic complications
0.000 0.011 0.989
E65-E68 Obesity and other hyperalimentation
0.000 0.016 0.984
E10.1 With ketoacidosis
0.000 0.016 0.984
E66 Obesity
0.000 0.026 0.974
E66.8 Other obesity
0.000 0.043 0.957
E14 Unspecified diabetes mellitus
0.000 0.062 0.938
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.089 0.911
E66.9 Obesity, unspecified
0.000 0.106 0.894
M06 Other rheumatoid arthritis
0.000 0.110 0.889
E14.9 Without complications
0.000 0.115 0.885
E10.5 With peripheral circulatory complications
0.000 0.116 0.884
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.122 0.878
E11.5 With peripheral circulatory complications
0.000 0.137 0.863
E11.4 With neurological complications
0.000 0.157 0.843
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.158 0.842
E10.4 With neurological complications
0.000 0.167 0.833
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.169 0.831
E11.9 Without complications
0.000 0.178 0.822
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.185 0.815
E10.2 With renal complications
0.000 0.188 0.812
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.218 0.782
E11.2 With renal complications
0.000 0.219 0.781
E05.9 Thyrotoxicosis, unspecified
0.000 0.229 0.771
E06 Thyroiditis
0.000 0.233 0.767
M05-M14 Inflammatory polyarthropathies
0.000 0.235 0.764
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.249 0.751
M05 Seropositive rheumatoid arthritis
0.000 0.257 0.743
M06.0 Seronegative rheumatoid arthritis
0.000 0.270 0.729
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.273 0.727
M06.3 Rheumatoid nodule
0.000 0.279 0.721
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.716
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.716
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.284 0.716
E14.3 With ophthalmic complications
0.000 0.284 0.716
E11.7 With multiple complications
0.000 0.285 0.715
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.294 0.706
E67 Other hyperalimentation
0.000 0.294 0.706
E68 Sequelae of hyperalimentation
0.000 0.294 0.706
E11.1 With ketoacidosis
0.000 0.295 0.705
E66.1 Drug-induced obesity
0.000 0.301 0.698
E66.0 Obesity due to excess calories
0.000 0.301 0.698
E65 Localised adiposity
0.000 0.305 0.695
E50-E64 Other nutritional deficiencies
0.000 0.306 0.694
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.316 0.684
E11.8 With unspecified complications
0.000 0.326 0.674
E14.8 With unspecified complications
0.000 0.327 0.672
E14.7 With multiple complications
0.000 0.327 0.672
E14.6 With other specified complications
0.000 0.327 0.672
E14.5 With peripheral circulatory complications
0.000 0.327 0.672
E14.4 With neurological complications
0.000 0.327 0.672
E14.2 Withrenal complications
0.000 0.327 0.672
E14.1 With ketoacidosis
0.000 0.327 0.672
E14.0 With coma
0.000 0.327 0.672
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.339 0.661
E05.8 Other thyrotoxicosis
0.000 0.347 0.653
E05.5 Thyroid crisis or storm
0.000 0.347 0.653
E05.4 Thyrotoxicosis factitia
0.000 0.347 0.653
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.347 0.653
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.347 0.653
E40-E46 Malnutrition
0.000 0.350 0.650
E11.6 With other specified complications
0.000 0.352 0.648
M06.8 Other specified rheumatoid arthritis
0.000 0.362 0.638
M06.2 Rheumatoid bursitis
0.000 0.362 0.638
M06.1 Adult-onset Still's disease
0.000 0.362 0.638
E06.3 Autoimmune thyroiditis
0.000 0.380 0.620
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.384 0.616
E07 Other disorders of thyroid
0.000 0.386 0.614
M13 Other arthritis
0.000 0.397 0.603
M06.34 Rheumatoid nodule (Hand)
0.000 0.400 0.600
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.401 0.599
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.407 0.593
M14 Arthropathies in other diseases classified elsewhere
0.000 0.412 0.588
M10 Gout
0.000 0.418 0.581
E20-E35 Disorders of other endocrine glands
0.000 0.424 0.576
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.427 0.573
E13 Other specified diabetes mellitus
0.000 0.431 0.568
E61 Deficiency of other nutrient elements
0.000 0.435 0.565
E11.0 With coma
0.000 0.438 0.562
E03.8 Other specified hypothyroidism
0.000 0.446 0.554
E06.5 Other chronic thyroiditis
0.000 0.450 0.550
E06.4 Drug-induced thyroiditis
0.000 0.450 0.550
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.450 0.550
E06.1 Subacute thyroiditis
0.000 0.450 0.550
E06.0 Acute thyroiditis
0.000 0.450 0.550
M12 Other specific arthropathies
0.000 0.452 0.548
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.452 0.548
M08 Juvenile arthritis
0.000 0.452 0.548
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.452 0.548
M05.8 Other seropositive rheumatoid arthritis
0.000 0.467 0.532
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.467 0.532
M05.2 Rheumatoid vasculitis
0.000 0.467 0.532
M05.1 Rheumatoid lung disease
0.000 0.467 0.532
M05.0 Felty's syndrome
0.000 0.467 0.532
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.477 0.523
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.477 0.523
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.477 0.523
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.477 0.523
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.477 0.523
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.477 0.523
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.477 0.523
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.477 0.523
E06.9 Thyroiditis, unspecified
0.000 0.478 0.522
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.478 0.521
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.478 0.521
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.478 0.521
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.478 0.521
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.478 0.521
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.478 0.521
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.478 0.521
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.478 0.521
M06.4 Inflammatory polyarthropathy
0.001 0.482 0.517
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.483 0.517
M06.38 Rheumatoid nodule (Other)
0.000 0.483 0.517
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.483 0.517
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.483 0.517
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.483 0.517
M06.33 Rheumatoid nodule (Forearm)
0.000 0.483 0.517
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.483 0.517
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.483 0.517
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.483 0.517
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M13.0 Polyarthritis, unspecified
0.000 0.491 0.509
E67.8 Other specified hyperalimentation
0.000 0.494 0.506
E67.3 Hypervitaminosis D
0.000 0.494 0.506
E67.2 Megavitamin-B6 syndrome
0.000 0.494 0.506
E67.1 Hypercarotenaemia
0.000 0.494 0.506
E67.0 Hypervitaminosis A
0.000 0.494 0.506
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.503 0.497
E63 Other nutritional deficiencies
0.000 0.503 0.497
E56 Other vitamin deficiencies
0.000 0.503 0.497
E51 Thiamine deficiency
0.000 0.503 0.497
E50 Vitamin A deficiency
0.000 0.503 0.497
E60 Dietary zinc deficiency
0.000 0.503 0.497
E59 Dietary selenium deficiency
0.000 0.503 0.497
E58 Dietary calcium deficiency
0.000 0.503 0.497
E54 Ascorbic acid deficiency
0.000 0.503 0.497
E52 Niacin deficiency [pellagra]
0.000 0.503 0.497
E53 Deficiency of other B group vitamins
0.000 0.521 0.479
E15 Nondiabetic hypoglycaemic coma
0.000 0.526 0.474
E61.1 Iron deficiency
0.000 0.527 0.473
E27 Other disorders of adrenal gland
0.000 0.531 0.469
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.534 0.466
E45 Retarded development following protein-energy malnutrition
0.000 0.534 0.466
E43 Unspecified severe protein-energy malnutrition
0.000 0.534 0.466
E42 Marasmic kwashiorkor
0.000 0.534 0.466
E41 Nutritional marasmus
0.000 0.534 0.466
E40 Kwashiorkor
0.000 0.534 0.466
M14.6 Neuropathic arthropathy
0.000 0.538 0.462
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.542 0.457
M06.18 Adult-onset Still's disease (Other)
0.000 0.542 0.457
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.542 0.457
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.542 0.457
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.542 0.457
M06.14 Adult-onset Still's disease (Hand)
0.000 0.542 0.457
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.542 0.457
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.542 0.457
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.542 0.457
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.542 0.457
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.542 0.457
M06.28 Rheumatoid bursitis (Other)
0.000 0.542 0.457
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.542 0.457
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.542 0.457
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.542 0.457
M06.24 Rheumatoid bursitis (Hand)
0.000 0.542 0.457
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.542 0.457
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.542 0.457
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.542 0.457
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.542 0.457
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.542 0.457
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.542 0.457
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.542 0.457
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.542 0.457
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.542 0.457
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.542 0.457
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.542 0.457
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.542 0.457
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.542 0.457
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.542 0.457
M11 Other crystal arthropathies
0.001 0.547 0.453
M10.9 Gout, unspecified
0.000 0.550 0.450
M13.00 Polyarthritis, unspecified (Multiple sites)
0.000 0.552 0.448
E07.1 Dyshormogenetic goitre
0.000 0.560 0.440
E07.0 Hypersecretion of calcitonin
0.000 0.560 0.440
E27.1 Primary adrenocortical insufficiency
0.000 0.566 0.434
M13.8 Other specified arthritis
0.000 0.567 0.432
M13.1 Monoarthritis, not elsewhere classified
0.000 0.567 0.432
M07 Psoriatic and enteropathic arthropathies
0.000 0.569 0.431
E07.8 Other specified disorders of thyroid
0.000 0.571 0.428
E23 Hypofunction and other disorders of pituitary gland
0.000 0.577 0.423
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.578 0.422
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.578 0.422
M14.4 Arthropathy in amyloidosis
0.000 0.578 0.422
M14.3 Lipoid dermatoarthritis
0.000 0.578 0.422
M14.2 Diabetic arthropathy
0.000 0.578 0.422
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.578 0.422
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.578 0.422
E16 Other disorders of pancreatic internal secretion
0.000 0.582 0.418
M10.4 Other secondary gout
0.000 0.583 0.417
M10.3 Gout due to impairment of renal function
0.000 0.583 0.417
M10.2 Drug-induced gout
0.000 0.583 0.417
M10.1 Lead-induced gout
0.000 0.583 0.417
M10.0 Idiopathic gout
0.000 0.583 0.417
E34 Other endocrine disorders
0.000 0.584 0.416
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.587 0.413
E32 Diseases of thymus
0.000 0.587 0.413
E31 Polyglandular dysfunction
0.000 0.587 0.413
E30 Disorders of puberty, not elsewhere classified
0.000 0.587 0.413
E25 Adrenogenital disorders
0.000 0.587 0.413
E20 Hypoparathyroidism
0.000 0.587 0.413
M10.97 Gout, unspecified (Ankle and foot)
0.000 0.590 0.410
E28 Ovarian dysfunction
0.000 0.591 0.409
E13.8 With unspecified complications
0.000 0.592 0.407
E13.7 With multiple complications
0.000 0.592 0.407
E13.6 With other specified complications
0.000 0.592 0.407
E13.5 With peripheral circulatory complications
0.000 0.592 0.407
E13.4 With neurological complications
0.000 0.592 0.407
E13.3 With ophthalmic complications
0.000 0.592 0.407
E13.2 With renal complications
0.000 0.592 0.407
E13.1 With ketoacidosis
0.000 0.592 0.407
E13.0 With coma
0.000 0.592 0.407
E61.9 Deficiency of nutrient element, unspecified
0.000 0.595 0.405
E61.8 Deficiency of other specified nutrient elements
0.000 0.595 0.405
E61.7 Deficiency of multiple nutrient elements
0.000 0.595 0.405
E61.6 Vanadium deficiency
0.000 0.595 0.405
E61.5 Molybdenum deficiency
0.000 0.595 0.405
E61.4 Chromium deficiency
0.000 0.595 0.405
E61.3 Manganese deficiency
0.000 0.595 0.405
E61.2 Magnesium deficiency
0.000 0.595 0.405
E61.0 Copper deficiency
0.000 0.595 0.405
E29 Testicular dysfunction
0.000 0.597 0.403
E46 Unspecified protein-energy malnutrition
0.000 0.600 0.400
M08.9 Juvenile arthritis, unspecified
0.000 0.607 0.393
M08.8 Other juvenile arthritis
0.000 0.607 0.393
M08.4 Pauciarticular juvenile arthritis
0.000 0.607 0.393
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.607 0.393
M08.2 Juvenile arthritis with systemic onset
0.000 0.607 0.393
M08.1 Juvenile ankylosing spondylitis
0.000 0.607 0.393
M08.0 Juvenile rheumatoid arthritis
0.000 0.607 0.393
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.607 0.393
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.607 0.393
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.607 0.393
M09.0 Juvenile arthritis in psoriasis
0.000 0.607 0.393
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.607 0.393
M12.5 Traumatic arthropathy
0.000 0.607 0.393
M12.4 Intermittent hydrarthrosis
0.000 0.607 0.393
M12.3 Palindromic rheumatism
0.000 0.607 0.393
M12.2 Villonodular synovitis (pigmented)
0.000 0.607 0.393
M12.1 Kaschin-Beck disease
0.000 0.607 0.393
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.607 0.393
M13.9 Arthritis, unspecified
0.000 0.607 0.393
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.001 0.610 0.390
E55 Vitamin D deficiency
0.000 0.612 0.388
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.612 0.388
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.615 0.385
M05.09 Felty's syndrome (Site unspecified)
0.000 0.618 0.382
M05.08 Felty's syndrome (Other)
0.000 0.618 0.382
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.618 0.382
M05.06 Felty's syndrome (Lower leg)
0.000 0.618 0.382
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.618 0.382
M05.04 Felty's syndrome (Hand)
0.000 0.618 0.382
M05.03 Felty's syndrome (Forearm)
0.000 0.618 0.382
M05.02 Felty's syndrome (Upper arm)
0.000 0.618 0.382
M05.01 Felty's syndrome (Shoulder region)
0.000 0.618 0.382
M05.00 Felty's syndrome (Multiple sites)
0.000 0.618 0.382
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.618 0.382
M05.18 Rheumatoid lung disease (Other)
0.000 0.618 0.382
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.618 0.382
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.618 0.382
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.618 0.382
M05.14 Rheumatoid lung disease (Hand)
0.000 0.618 0.382
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.618 0.382
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.618 0.382
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.618 0.382
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.618 0.382
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.618 0.382
M05.28 Rheumatoid vasculitis (Other)
0.000 0.618 0.382
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.618 0.382
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.618 0.382
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.618 0.382
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.618 0.382
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.618 0.382
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.618 0.382
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.618 0.382
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.618 0.382
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.618 0.382
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.618 0.382
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.618 0.382
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.618 0.382
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.618 0.382
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.618 0.382
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.618 0.382
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.618 0.382
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.618 0.382
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.618 0.382
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.618 0.382
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.618 0.382
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.618 0.382
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.618 0.382
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.618 0.382
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.618 0.382
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.618 0.382
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.618 0.382
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.618 0.382
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.618 0.382
E53.8 Deficiency of other specified B group vitamins
0.000 0.627 0.373
M06.48 Inflammatory polyarthropathy (Other)
0.001 0.629 0.371
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.001 0.629 0.371
M06.46 Inflammatory polyarthropathy (Lower leg)
0.001 0.629 0.371
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.001 0.629 0.371
M06.44 Inflammatory polyarthropathy (Hand)
0.001 0.629 0.371
M06.43 Inflammatory polyarthropathy (Forearm)
0.001 0.629 0.371
M06.42 Inflammatory polyarthropathy (Upper arm)
0.001 0.629 0.371
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.001 0.629 0.371
E26 Hyperaldosteronism
0.000 0.629 0.371
M13.94 Arthritis, unspecified (Hand)
0.000 0.631 0.369
M13.08 Polyarthritis, unspecified (Other)
0.000 0.635 0.365
M13.07 Polyarthritis, unspecified (Ankle and foot)
0.000 0.635 0.365
M13.06 Polyarthritis, unspecified (Lower leg)
0.000 0.635 0.365
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)
0.000 0.635 0.365
M13.04 Polyarthritis, unspecified (Hand)
0.000 0.635 0.365
M13.03 Polyarthritis, unspecified (Forearm)
0.000 0.635 0.365
M13.02 Polyarthritis, unspecified (Upper arm)
0.000 0.635 0.365
M13.01 Polyarthritis, unspecified (Shoulder region)
0.000 0.635 0.365
E24 Cushing's syndrome
0.000 0.638 0.362
E50.9 Vitamin A deficiency, unspecified
0.000 0.643 0.357
E50.8 Other manifestations of vitamin A deficiency
0.000 0.643 0.357
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.643 0.357
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.643 0.357
E50.5 Vitamin A deficiency with night blindness
0.000 0.643 0.357
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.643 0.357
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.643 0.357
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.643 0.357
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.643 0.357
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.643 0.357
E51.9 Thiamine deficiency, unspecified
0.000 0.643 0.357
E51.8 Other manifestations of thiamine deficiency
0.000 0.643 0.357
E51.2 Wernicke's encephalopathy
0.000 0.643 0.357
E51.1 Beriberi
0.000 0.643 0.357
E56.9 Vitamin deficiency, unspecified
0.000 0.643 0.357
E56.8 Deficiency of other vitamins
0.000 0.643 0.357
E56.1 Deficiency of vitamin K
0.000 0.643 0.357
E56.0 Deficiency of vitamin E
0.000 0.643 0.357
E63.9 Nutritional deficiency, unspecified
0.000 0.643 0.357
E63.8 Other specified nutritional deficiencies
0.000 0.643 0.357
E63.1 Imbalance of constituents of food intake
0.000 0.643 0.357
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.643 0.357
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.643 0.357
E64.8 Sequelae of other nutritional deficiencies
0.000 0.643 0.357
E64.3 Sequelae of rickets
0.000 0.643 0.357
E64.2 Sequelae of vitamin C deficiency
0.000 0.643 0.357
E64.1 Sequelae of vitamin A deficiency
0.000 0.643 0.357
E64.0 Sequelae of protein-energy malnutrition
0.000 0.643 0.357
E07.9 Disorder of thyroid, unspecified
0.000 0.645 0.355
M13.09 Polyarthritis, unspecified (Site unspecified)
0.000 0.648 0.351
E27.8 Other specified disorders of adrenal gland
0.000 0.652 0.348
E53.1 Pyridoxine deficiency
0.000 0.656 0.343
E53.0 Riboflavin deficiency
0.000 0.656 0.343
M10.96 Gout, unspecified (Lower leg)
0.000 0.661 0.339
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.663 0.337
E27.5 Adrenomedullary hyperfunction
0.000 0.663 0.336
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.663 0.336
E27.2 Addisonian crisis
0.000 0.663 0.336
E27.0 Other adrenocortical overactivity
0.000 0.663 0.336
E44.1 Mild protein-energy malnutrition
0.000 0.665 0.334
E44.0 Moderate protein-energy malnutrition
0.000 0.665 0.334
E22 Hyperfunction of pituitary gland
0.000 0.666 0.334
E23.2 Diabetes insipidus
0.000 0.667 0.333
M11.9 Crystal arthropathy, unspecified
0.001 0.675 0.325
M11.8 Other specified crystal arthropathies
0.001 0.675 0.325
M11.1 Familial chondrocalcinosis
0.001 0.675 0.325
M11.0 Hydroxyapatite deposition disease
0.001 0.675 0.325
M10.98 Gout, unspecified (Other)
0.000 0.677 0.323
M10.95 Gout, unspecified (Pelvic region and thigh)
0.000 0.677 0.323
M10.93 Gout, unspecified (Forearm)
0.000 0.677 0.323
M10.92 Gout, unspecified (Upper arm)
0.000 0.677 0.323
M10.91 Gout, unspecified (Shoulder region)
0.000 0.677 0.323
M10.90 Gout, unspecified (Multiple sites)
0.000 0.677 0.323
M10.94 Gout, unspecified (Hand)
0.000 0.681 0.319
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.000 0.681 0.319
E34.9 Endocrine disorder, unspecified
0.000 0.682 0.318
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)
0.000 0.690 0.310
M13.18 Monoarthritis, not elsewhere classified (Other)
0.000 0.690 0.310
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)
0.000 0.690 0.310
M13.16 Monoarthritis, not elsewhere classified (Lower leg)
0.000 0.690 0.310
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)
0.000 0.690 0.310
M13.14 Monoarthritis, not elsewhere classified (Hand)
0.000 0.690 0.310
M13.13 Monoarthritis, not elsewhere classified (Forearm)
0.000 0.690 0.310
M13.12 Monoarthritis, not elsewhere classified (Upper arm)
0.000 0.690 0.310
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)
0.000 0.690 0.310
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)
0.000 0.690 0.310
M13.89 Other specified arthritis (Site unspecified)
0.000 0.690 0.310
M13.88 Other specified arthritis (Other)
0.000 0.690 0.310
M13.87 Other specified arthritis (Ankle and foot)
0.000 0.690 0.310
M13.86 Other specified arthritis (Lower leg)
0.000 0.690 0.310
M13.85 Other specified arthritis (Pelvic region and thigh)
0.000 0.690 0.310
M13.84 Other specified arthritis (Hand)
0.000 0.690 0.310
M13.83 Other specified arthritis (Forearm)
0.000 0.690 0.310
M13.82 Other specified arthritis (Upper arm)
0.000 0.690 0.310
M13.81 Other specified arthritis (Shoulder region)
0.000 0.690 0.310
M13.80 Other specified arthritis (Multiple sites)
0.000 0.690 0.310
M07.6 Other enteropathic arthropathies
0.000 0.691 0.309
M07.5 Arthropathy in ulcerative colitis
0.000 0.691 0.309
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.691 0.309
M07.2 Psoriatic spondylitis
0.000 0.691 0.309
M07.1 Arthritis mutilans
0.000 0.691 0.309
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.691 0.309
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.691 0.309
M13.93 Arthritis, unspecified (Forearm)
0.000 0.696 0.304
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.697 0.303
E23.1 Drug-induced hypopituitarism
0.000 0.697 0.303
E23.7 Disorder of pituitary gland, unspecified
0.000 0.697 0.303
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.700 0.300
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.700 0.300
E16.4 Abnormal secretion of gastrin
0.000 0.700 0.300
E16.3 Increased secretion of glucagon
0.000 0.700 0.300
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.700 0.300
M10.09 Idiopathic gout (Site unspecified)
0.000 0.701 0.299
M10.08 Idiopathic gout (Other)
0.000 0.701 0.299
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.701 0.299
M10.06 Idiopathic gout (Lower leg)
0.000 0.701 0.299
M10.05 Idiopathic gout (Pelvic region and thigh)
0.000 0.701 0.299
M10.04 Idiopathic gout (Hand)
0.000 0.701 0.299
M10.03 Idiopathic gout (Forearm)
0.000 0.701 0.299
M10.02 Idiopathic gout (Upper arm)
0.000 0.701 0.299
M10.01 Idiopathic gout (Shoulder region)
0.000 0.701 0.299
M10.00 Idiopathic gout (Multiple sites)
0.000 0.701 0.299
M10.19 Lead-induced gout (Site unspecified)
0.000 0.701 0.299
M10.18 Lead-induced gout (Other)
0.000 0.701 0.299
M10.17 Lead-induced gout (Ankle and foot)
0.000 0.701 0.299
M10.16 Lead-induced gout (Lower leg)
0.000 0.701 0.299
M10.15 Lead-induced gout (Pelvic region and thigh)
0.000 0.701 0.299
M10.14 Lead-induced gout (Hand)
0.000 0.701 0.299
M10.13 Lead-induced gout (Forearm)
0.000 0.701 0.299
M10.12 Lead-induced gout (Upper arm)
0.000 0.701 0.299
M10.11 Lead-induced gout (Shoulder region)
0.000 0.701 0.299
M10.10 Lead-induced gout (Multiple sites)
0.000 0.701 0.299
M10.29 Drug-induced gout (Site unspecified)
0.000 0.701 0.299
M10.28 Drug-induced gout (Other)
0.000 0.701 0.299
M10.27 Drug-induced gout (Ankle and foot)
0.000 0.701 0.299
M10.26 Drug-induced gout (Lower leg)
0.000 0.701 0.299
M10.25 Drug-induced gout (Pelvic region and thigh)
0.000 0.701 0.299
M10.24 Drug-induced gout (Hand)
0.000 0.701 0.299
M10.23 Drug-induced gout (Forearm)
0.000 0.701 0.299
M10.22 Drug-induced gout (Upper arm)
0.000 0.701 0.299
M10.21 Drug-induced gout (Shoulder region)
0.000 0.701 0.299
M10.20 Drug-induced gout (Multiple sites)
0.000 0.701 0.299
M10.39 Gout due to impairment of renal function (Site unspecified)
0.000 0.701 0.299
M10.38 Gout due to impairment of renal function (Other)
0.000 0.701 0.299
M10.37 Gout due to impairment of renal function (Ankle and foot)
0.000 0.701 0.299
M10.36 Gout due to impairment of renal function (Lower leg)
0.000 0.701 0.299
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)
0.000 0.701 0.299
M10.34 Gout due to impairment of renal function (Hand)
0.000 0.701 0.299
M10.33 Gout due to impairment of renal function (Forearm)
0.000 0.701 0.299
M10.32 Gout due to impairment of renal function (Upper arm)
0.000 0.701 0.299
M10.31 Gout due to impairment of renal function (Shoulder region)
0.000 0.701 0.299
M10.30 Gout due to impairment of renal function (Multiple sites)
0.000 0.701 0.299
M10.49 Other secondary gout (Site unspecified)
0.000 0.701 0.299
M10.48 Other secondary gout (Other)
0.000 0.701 0.299
M10.47 Other secondary gout (Ankle and foot)
0.000 0.701 0.299

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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