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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2270190
log Bayes Factor = 23.9825
Chromosome 6   position 31,080,586  (GRCh37) Explore rs2270190 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.055 0.945
L40 Psoriasis
0.000 0.056 0.944
L40.5 Arthropathic psoriasis
0.000 0.057 0.943
L40.0 Psoriasis vulgaris
0.000 0.142 0.858
L40.4 Guttate psoriasis
0.000 0.323 0.677
L40.3 Pustulosis palmaris et plantaris
0.000 0.323 0.677
L40.2 Acrodermatitis continua
0.000 0.323 0.677
L40.1 Generalised pustular psoriasis
0.000 0.323 0.677
L40.8 Other psoriasis
0.000 0.338 0.662
K90 Intestinal malabsorption
0.000 0.409 0.591
E03 Other hypothyroidism
0.413 0.490 0.097
K90.9 Intestinal malabsorption, unspecified
0.000 0.531 0.469
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.537 0.463
K90.8 Other intestinal malabsorption
0.000 0.576 0.424
K90.3 Pancreatic steatorrhoea
0.000 0.576 0.424
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.576 0.424
K90.1 Tropical sprue
0.000 0.576 0.424
L40-L45 Papulosquamous disorders
0.000 0.582 0.418
E03.5 Myxoedema coma
0.296 0.634 0.070
E03.4 Atrophy of thyroid (acquired)
0.296 0.634 0.070
E03.3 Postinfectious hypothyroidism
0.296 0.634 0.070
E03.1 Congenital hypothyroidism without goitre
0.296 0.634 0.070
E03.0 Congenital hypothyroidism with diffuse goitre
0.296 0.634 0.070
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.293 0.640 0.066
E03.8 Other specified hypothyroidism
0.284 0.651 0.065
L42 Pityriasis rosea
0.000 0.688 0.312
L44 Other papulosquamous disorders
0.000 0.700 0.300
L41 Parapsoriasis
0.000 0.700 0.300
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.700 0.300
L43 Lichen planus
0.000 0.702 0.298
E10-E14 Diabetes mellitus
0.000 0.714 0.286
E16.2 Hypoglycaemia, unspecified
0.000 0.715 0.284
E10 Insulin-dependent diabetes mellitus
0.000 0.717 0.283
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.717 0.282
E16 Other disorders of pancreatic internal secretion
0.000 0.718 0.282
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.719 0.281
E00-E07 Disorders of thyroid gland
0.021 0.721 0.258
E11 Non-insulin-dependent diabetes mellitus
0.000 0.723 0.277
E10.3 With ophthalmic complications
0.000 0.727 0.273
E50-E64 Other nutritional deficiencies
0.000 0.735 0.265
E05 Thyrotoxicosis [hyperthyroidism]
0.004 0.742 0.254
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.743 0.257
E11.4 With neurological complications
0.000 0.745 0.255
E10.2 With renal complications
0.000 0.745 0.255
E55 Vitamin D deficiency
0.000 0.747 0.253
E55.9 Vitamin D deficiency, unspecified
0.000 0.755 0.245
E11.8 With unspecified complications
0.000 0.763 0.237
E65-E68 Obesity and other hyperalimentation
0.000 0.763 0.237
E10.1 With ketoacidosis
0.000 0.767 0.233
E06 Thyroiditis
0.009 0.770 0.221
E11.6 With other specified complications
0.000 0.773 0.227
E11.2 With renal complications
0.000 0.774 0.226
E11.3 With ophthalmic complications
0.000 0.776 0.224
E11.0 With coma
0.000 0.779 0.221
E10.4 With neurological complications
0.000 0.780 0.220
E11.5 With peripheral circulatory complications
0.000 0.782 0.218
L41.9 Parapsoriasis, unspecified
0.000 0.785 0.215
L41.8 Other parapsoriasis
0.000 0.785 0.215
L41.5 Retiform parapsoriasis
0.000 0.785 0.215
L41.4 Large plaque parapsoriasis
0.000 0.785 0.215
L41.3 Small plaque parapsoriasis
0.000 0.785 0.215
L41.2 Lymphomatoid papulosis
0.000 0.785 0.215
L41.1 Pityriasis lichenoides chronica
0.000 0.785 0.215
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.785 0.215
L44.9 Papulosquamous disorder, unspecified
0.000 0.785 0.215
L44.8 Other specified papulosquamous disorders
0.000 0.785 0.215
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.785 0.215
L44.3 Lichen ruber moniliformis
0.000 0.785 0.215
L44.2 Lichen striatus
0.000 0.785 0.215
L44.1 Lichen nitidus
0.000 0.785 0.215
L44.0 Pityriasis rubra pilaris
0.000 0.785 0.215
L43.8 Other lichen planus
0.000 0.786 0.214
L43.3 Subacute (active) lichen planus
0.000 0.786 0.214
L43.2 Lichenoid drug reaction
0.000 0.786 0.214
L43.1 Bullous lichen planus
0.000 0.786 0.214
L43.0 Hypertrophic lichen planus
0.000 0.786 0.214
L43.9 Lichen planus, unspecified
0.000 0.788 0.212
E16.1 Other hypoglycaemia
0.000 0.793 0.207
E10.0 With coma
0.000 0.793 0.206
E12 Malnutrition-related diabetes mellitus
0.000 0.795 0.205
E10.8 With unspecified complications
0.000 0.796 0.204
E10.7 With multiple complications
0.000 0.797 0.203
E13 Other specified diabetes mellitus
0.000 0.797 0.203
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.798 0.202
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.798 0.202
E16.4 Abnormal secretion of gastrin
0.000 0.798 0.202
E16.3 Increased secretion of glucagon
0.000 0.798 0.202
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.798 0.202
E15 Nondiabetic hypoglycaemic coma
0.000 0.798 0.202
E65 Localised adiposity
0.000 0.800 0.200
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.015 0.800 0.185
E00 Congenital iodine-deficiency syndrome
0.015 0.800 0.185
E02 Subclinical iodine-deficiency hypothyroidism
0.015 0.800 0.185
E10.6 With other specified complications
0.000 0.800 0.200
E11.7 With multiple complications
0.000 0.801 0.199
E10.5 With peripheral circulatory complications
0.000 0.801 0.199
E61 Deficiency of other nutrient elements
0.000 0.802 0.198
E06.9 Thyroiditis, unspecified
0.004 0.804 0.192
E11.1 With ketoacidosis
0.000 0.806 0.194
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.810 0.190
E63 Other nutritional deficiencies
0.000 0.810 0.190
E56 Other vitamin deficiencies
0.000 0.810 0.190
E51 Thiamine deficiency
0.000 0.810 0.190
E50 Vitamin A deficiency
0.000 0.810 0.190
E60 Dietary zinc deficiency
0.000 0.810 0.190
E59 Dietary selenium deficiency
0.000 0.810 0.190
E58 Dietary calcium deficiency
0.000 0.810 0.190
E54 Ascorbic acid deficiency
0.000 0.810 0.190
E52 Niacin deficiency [pellagra]
0.000 0.810 0.190
E05.8 Other thyrotoxicosis
0.003 0.815 0.182
E05.5 Thyroid crisis or storm
0.003 0.815 0.182
E05.4 Thyrotoxicosis factitia
0.003 0.815 0.182
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.003 0.815 0.182
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.003 0.815 0.182
E55.0 Rickets, active
0.000 0.818 0.182
E53 Deficiency of other B group vitamins
0.000 0.820 0.180
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.002 0.820 0.178
E66 Obesity
0.000 0.823 0.177
E67 Other hyperalimentation
0.000 0.830 0.170
E68 Sequelae of hyperalimentation
0.000 0.830 0.170
E06.3 Autoimmune thyroiditis
0.004 0.831 0.165
E40-E46 Malnutrition
0.000 0.832 0.168
C18.7 Sigmoid colon
0.166 0.834 0.000
E66.8 Other obesity
0.000 0.834 0.166
E06.5 Other chronic thyroiditis
0.007 0.835 0.159
E06.4 Drug-induced thyroiditis
0.007 0.835 0.159
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.007 0.835 0.159
E06.1 Subacute thyroiditis
0.007 0.835 0.159
E06.0 Acute thyroiditis
0.007 0.835 0.159
C18 Malignant neoplasm of colon
0.165 0.835 0.000
C18.1 Appendix
0.158 0.842 0.000
C77.2 Intra-abdominal lymph nodes
0.151 0.849 0.000
E61.1 Iron deficiency
0.000 0.850 0.150
E12.9 Without complications
0.000 0.853 0.147
E12.8 With unspecified complications
0.000 0.853 0.147
E12.7 With multiple complications
0.000 0.853 0.147
E12.6 With other specified complications
0.000 0.853 0.147
E12.5 With peripheral circulatory complications
0.000 0.853 0.147
E12.4 With neurological complications
0.000 0.853 0.147
E12.3 With ophthalmic complications
0.000 0.853 0.147
E12.2 With renal complications
0.000 0.853 0.147
E12.1 With ketoacidosis
0.000 0.853 0.147
E12.0 With coma
0.000 0.853 0.147
E13.8 With unspecified complications
0.000 0.854 0.146
E13.7 With multiple complications
0.000 0.854 0.146
E13.6 With other specified complications
0.000 0.854 0.146
E13.5 With peripheral circulatory complications
0.000 0.854 0.146
E13.4 With neurological complications
0.000 0.854 0.146
E13.3 With ophthalmic complications
0.000 0.854 0.146
E13.2 With renal complications
0.000 0.854 0.146
E13.1 With ketoacidosis
0.000 0.854 0.146
E13.0 With coma
0.000 0.854 0.146
E83.1 Disorders of iron metabolism
0.000 0.854 0.146
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.011 0.856 0.133
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.011 0.856 0.133
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.011 0.856 0.133
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.011 0.856 0.133
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.011 0.856 0.133
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.011 0.856 0.133
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.011 0.856 0.133
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.011 0.856 0.133
E13.9 Without complications
0.000 0.856 0.143
E61.9 Deficiency of nutrient element, unspecified
0.000 0.858 0.142
E61.8 Deficiency of other specified nutrient elements
0.000 0.858 0.142
E61.7 Deficiency of multiple nutrient elements
0.000 0.858 0.142
E61.6 Vanadium deficiency
0.000 0.858 0.142
E61.5 Molybdenum deficiency
0.000 0.858 0.142
E61.4 Chromium deficiency
0.000 0.858 0.142
E61.3 Manganese deficiency
0.000 0.858 0.142
E61.2 Magnesium deficiency
0.000 0.858 0.142
E61.0 Copper deficiency
0.000 0.858 0.142
E70-E90 Metabolic disorders
0.000 0.859 0.141
E83 Disorders of mineral metabolism
0.000 0.862 0.138
E07 Other disorders of thyroid
0.017 0.862 0.122
C15-C26 Malignant neoplasms of digestive organs
0.138 0.862 0.000
C21 Malignant neoplasm of anus and anal canal
0.138 0.862 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.863 0.136
E50.8 Other manifestations of vitamin A deficiency
0.000 0.863 0.136
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.863 0.136
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.863 0.136
E50.5 Vitamin A deficiency with night blindness
0.000 0.863 0.136
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.863 0.136
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.863 0.136
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.863 0.136
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.863 0.136
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.863 0.136
E51.9 Thiamine deficiency, unspecified
0.000 0.863 0.136
E51.8 Other manifestations of thiamine deficiency
0.000 0.863 0.136
E51.2 Wernicke's encephalopathy
0.000 0.863 0.136
E51.1 Beriberi
0.000 0.863 0.136
E56.9 Vitamin deficiency, unspecified
0.000 0.863 0.136
E56.8 Deficiency of other vitamins
0.000 0.863 0.136
E56.1 Deficiency of vitamin K
0.000 0.863 0.136
E56.0 Deficiency of vitamin E
0.000 0.863 0.136
E63.9 Nutritional deficiency, unspecified
0.000 0.863 0.136
E63.8 Other specified nutritional deficiencies
0.000 0.863 0.136
E63.1 Imbalance of constituents of food intake
0.000 0.863 0.136
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.863 0.136
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.863 0.136
E64.8 Sequelae of other nutritional deficiencies
0.000 0.863 0.136
E64.3 Sequelae of rickets
0.000 0.863 0.136
E64.2 Sequelae of vitamin C deficiency
0.000 0.863 0.136
E64.1 Sequelae of vitamin A deficiency
0.000 0.863 0.136
E64.0 Sequelae of protein-energy malnutrition
0.000 0.863 0.136
E10.9 Without complications
0.000 0.864 0.136
C18.2 Ascending colon
0.136 0.864 0.000
C18.3 Hepatic flexure
0.134 0.866 0.000
C18.0 Caecum
0.134 0.866 0.000
C21.0 Anus, unspecified
0.131 0.869 0.000
C71 Malignant neoplasm of brain
0.130 0.870 0.000
E05.9 Thyrotoxicosis, unspecified
0.001 0.871 0.129
E53.9 Vitamin B deficiency, unspecified
0.000 0.871 0.129
E53.1 Pyridoxine deficiency
0.000 0.871 0.129
E53.0 Riboflavin deficiency
0.000 0.871 0.129
C21.1 Anal canal
0.128 0.871 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.128 0.872 0.000
C71.9 Brain, unspecified
0.127 0.873 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.873 0.127
E66.1 Drug-induced obesity
0.000 0.873 0.127
E66.0 Obesity due to excess calories
0.000 0.873 0.127
C18.5 Splenic flexure
0.125 0.875 0.000
C71.0 Cerebrum, except lobes and ventricles
0.123 0.877 0.000
C18.4 Transverse colon
0.123 0.877 0.000
E67.8 Other specified hyperalimentation
0.000 0.878 0.122
E67.3 Hypervitaminosis D
0.000 0.878 0.122
E67.2 Megavitamin-B6 syndrome
0.000 0.878 0.122
E67.1 Hypercarotenaemia
0.000 0.878 0.122
E67.0 Hypervitaminosis A
0.000 0.878 0.122
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.879 0.121
E45 Retarded development following protein-energy malnutrition
0.000 0.879 0.121
E43 Unspecified severe protein-energy malnutrition
0.000 0.879 0.121
E42 Marasmic kwashiorkor
0.000 0.879 0.121
E41 Nutritional marasmus
0.000 0.879 0.121
E40 Kwashiorkor
0.000 0.879 0.121
E85 Amyloidosis
0.000 0.880 0.120
E53.8 Deficiency of other specified B group vitamins
0.000 0.881 0.119
C18.8 Overlapping lesion of colon
0.119 0.881 0.000
C23 Malignant neoplasm of gallbladder
0.117 0.883 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.114 0.885 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.114 0.886 0.000
C18.6 Descending colon
0.113 0.887 0.000
C77.9 Lymph node, unspecified
0.113 0.887 0.000
C17 Malignant neoplasm of small intestine
0.111 0.888 0.000
E88 Other metabolic disorders
0.000 0.890 0.110
C77.4 Inguinal and lower limb lymph nodes
0.109 0.891 0.000
C71.1 Frontal lobe
0.107 0.893 0.000
C71.4 Occipital lobe
0.104 0.896 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.104 0.896 0.000
C71.2 Temporal lobe
0.104 0.896 0.000
C71.3 Parietal lobe
0.104 0.896 0.000
E14 Unspecified diabetes mellitus
0.000 0.897 0.103
C77.8 Lymph nodes of multiple regions
0.103 0.897 0.000
Chapter II Neoplasms
0.102 0.898 0.000
E84 Cystic fibrosis
0.000 0.899 0.101
E79 Disorders of purine and pyrimidine metabolism
0.000 0.899 0.101
E77 Disorders of glycoprotein metabolism
0.000 0.899 0.101
E76 Disorders of glycosaminoglycan metabolism
0.000 0.899 0.101
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.899 0.101
E72 Other disorders of amino-acid metabolism
0.000 0.899 0.101
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.899 0.101
E70 Disorders of aromatic amino-acid metabolism
0.000 0.899 0.101
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.899 0.101
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.100 0.900 0.000
E85.4 Organ-limited amyloidosis
0.000 0.900 0.100
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.100 0.900 0.000
E07.1 Dyshormogenetic goitre
0.012 0.901 0.087
E07.0 Hypersecretion of calcitonin
0.012 0.901 0.087
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.901 0.099
E83.8 Other disorders of mineral metabolism
0.000 0.901 0.099
E83.2 Disorders of zinc metabolism
0.000 0.901 0.099
E83.0 Disorders of copper metabolism
0.000 0.901 0.099
C21.2 Cloacogenic zone
0.099 0.901 0.000
C26.0 Intestinal tract, part unspecified
0.099 0.901 0.000
E83.5 Disorders of calcium metabolism
0.000 0.905 0.095
E74 Other disorders of carbohydrate metabolism
0.000 0.906 0.094
C17.9 Small intestine, unspecified
0.094 0.906 0.000
C71.7 Brain stem
0.094 0.906 0.000
C71.6 Cerebellum
0.094 0.906 0.000
C71.5 Cerebral ventricle
0.094 0.906 0.000
E85.9 Amyloidosis, unspecified
0.000 0.906 0.093
E07.8 Other specified disorders of thyroid
0.012 0.907 0.081
C77.0 Lymph nodes of head, face and neck
0.093 0.907 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.908 0.092
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.910 0.090
C71.8 Overlapping lesion of brain
0.089 0.911 0.000
C25 Malignant neoplasm of pancreas
0.089 0.911 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.088 0.911 0.000
C15 Malignant neoplasm of oesophagus
0.087 0.913 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.913 0.087
E44.0 Moderate protein-energy malnutrition
0.000 0.913 0.087
C77.5 Intrapelvic lymph nodes
0.087 0.913 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.086 0.913 0.000
E46 Unspecified protein-energy malnutrition
0.001 0.914 0.086
E85.8 Other amyloidosis
0.000 0.914 0.086
E85.3 Secondary systemic amyloidosis
0.000 0.914 0.086
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.914 0.086
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.914 0.086
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.914 0.086
C05 Malignant neoplasm of palate
0.085 0.915 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.085 0.915 0.000
E73 Lactose intolerance
0.000 0.916 0.084
C16 Malignant neoplasm of stomach
0.084 0.916 0.000
C01 Malignant neoplasm of base of tongue
0.083 0.917 0.000
C26.8 Overlapping lesion of digestive system
0.082 0.918 0.000
C26.1 Spleen
0.082 0.918 0.000
C17.2 Ileum
0.082 0.918 0.000
G35 Multiple sclerosis
0.000 0.918 0.082
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.082 0.918 0.000
C70 Malignant neoplasm of meninges
0.082 0.918 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.081 0.919 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.080 0.919 0.000
D00-D09 In situ neoplasms
0.080 0.920 0.000
C17.8 Overlapping lesion of small intestine
0.080 0.920 0.000
C17.3 Meckel's diverticulum
0.080 0.920 0.000
C17.1 Jejunum
0.080 0.920 0.000
C69 Malignant neoplasm of eye and adnexa
0.079 0.920 0.000
C07 Malignant neoplasm of parotid gland
0.079 0.921 0.000
C26.9 Ill-defined sites within the digestive system
0.079 0.921 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.921 0.079
E88.8 Other specified metabolic disorders
0.000 0.921 0.079
E88.3 Tumour lysis syndrome
0.000 0.921 0.079
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.921 0.079
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.000 0.921 0.079
E04 Other non-toxic goitre
0.007 0.922 0.071
C02.1 Border of tongue
0.077 0.923 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.923 0.077
C10 Malignant neoplasm of oropharynx
0.076 0.924 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.076 0.924 0.000
C17.0 Duodenum
0.075 0.925 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.075 0.925 0.000
D07.1 Vulva
0.075 0.925 0.000
C05.1 Soft palate
0.074 0.925 0.000
E14.8 With unspecified complications
0.000 0.926 0.074
E14.7 With multiple complications
0.000 0.926 0.074
E14.5 With peripheral circulatory complications
0.000 0.926 0.074
E14.4 With neurological complications
0.000 0.926 0.074
E14.2 Withrenal complications
0.000 0.926 0.074
E14.0 With coma
0.000 0.926 0.074
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.074 0.926 0.000
C77.1 Intrathoracic lymph nodes
0.074 0.926 0.000
C14.0 Pharynx, unspecified
0.073 0.927 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.927 0.073
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.927 0.073
E70.3 Albinism
0.000 0.927 0.073
E70.2 Disorders of tyrosine metabolism
0.000 0.927 0.073
E70.1 Other hyperphenylalaninaemias
0.000 0.927 0.073
E70.0 Classical phenylketonuria
0.000 0.927 0.073
E71.3 Disorders of fatty-acid metabolism
0.000 0.927 0.073
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.927 0.073
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.927 0.073
E71.0 Maple-syrup-urine disease
0.000 0.927 0.073
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.927 0.073
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.927 0.073
E72.5 Disorders of glycine metabolism
0.000 0.927 0.073
E72.4 Disorders of ornithine metabolism
0.000 0.927 0.073
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.927 0.073
E72.2 Disorders of urea cycle metabolism
0.000 0.927 0.073
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.927 0.073
E72.0 Disorders of amino-acid transport
0.000 0.927 0.073
E75.6 Lipid storage disorder, unspecified
0.000 0.927 0.073
E75.5 Other lipid storage disorders
0.000 0.927 0.073
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.927 0.073
E75.3 Sphingolipidosis, unspecified
0.000 0.927 0.073
E75.2 Other sphingolipidosis
0.000 0.927 0.073
E75.1 Other gangliosidosis
0.000 0.927 0.073
E75.0 GM2 gangliosidosis
0.000 0.927 0.073
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.927 0.073
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.927 0.073
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.927 0.073
E76.2 Other mucopolysaccharidoses
0.000 0.927 0.073
E76.1 Mucopolysaccharidosis, type II
0.000 0.927 0.073
E76.0 Mucopolysaccharidosis, type I
0.000 0.927 0.073
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.927 0.073
E77.8 Other disorders of glycoprotein metabolism
0.000 0.927 0.073
E77.1 Defects in glycoprotein degradation
0.000 0.927 0.073
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.927 0.073
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.927 0.073
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.927 0.073
E79.1 Lesch-Nyhan syndrome
0.000 0.927 0.073
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.927 0.073
E84.9 Cystic fibrosis, unspecified
0.000 0.927 0.073
E84.8 Cystic fibrosis with other manifestations
0.000 0.927 0.073
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.927 0.073
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.927 0.073
C13 Malignant neoplasm of hypopharynx
0.072 0.928 0.000
C11 Malignant neoplasm of nasopharynx
0.072 0.928 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.072 0.928 0.000
C03 Malignant neoplasm of gum
0.072 0.928 0.000
C00 Malignant neoplasm of lip
0.072 0.928 0.000
C18.9 Colon, unspecified
0.072 0.928 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.928 0.072
E83.4 Disorders of magnesium metabolism
0.000 0.929 0.071
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.070 0.929 0.000
C15.3 Upper third of oesophagus
0.070 0.930 0.000
C04 Malignant neoplasm of floor of mouth
0.069 0.931 0.000
E14.6 With other specified complications
0.000 0.931 0.069
C15.4 Middle third of oesophagus
0.068 0.932 0.000
C25.2 Tail of pancreas
0.068 0.932 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.932 0.068
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.932 0.068
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.932 0.068
E74.2 Disorders of galactose metabolism
0.000 0.932 0.068
E74.1 Disorders of fructose metabolism
0.000 0.932 0.068
E74.0 Glycogen storage disease
0.000 0.932 0.068
C76 Malignant neoplasm of other and ill-defined sites
0.067 0.933 0.000
E14.1 With ketoacidosis
0.000 0.933 0.067
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.933 0.066
E80.6 Other disorders of bilirubin metabolism
0.000 0.933 0.066
E80.5 Crigler-Najjar syndrome
0.000 0.933 0.066
E80.3 Defects of catalase and peroxydase
0.000 0.933 0.066
E80.1 Porphyria cutanea tarda
0.000 0.933 0.066
E80.0 Hereditary erythropoietic porphyria
0.000 0.933 0.066
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.066 0.934 0.000
D07.4 Penis
0.066 0.934 0.000
E80.4 Gilbert's syndrome
0.000 0.934 0.066
E14.3 With ophthalmic complications
0.000 0.934 0.066
C12 Malignant neoplasm of pyriform sinus
0.066 0.934 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.065 0.935 0.000
C16.0 Cardia
0.065 0.935 0.000
C24.1 Ampulla of Vater
0.065 0.935 0.000
C02.4 Lingual tonsil
0.064 0.936 0.000
C25.8 Overlapping lesion of pancreas
0.064 0.936 0.000
C25.7 Other parts of pancreas
0.064 0.936 0.000
C25.4 Endocrine pancreas
0.064 0.936 0.000
C25.3 Pancreatic duct
0.064 0.936 0.000
C24.8 Overlapping lesion of biliary tract
0.064 0.936 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.064 0.936 0.000
C24.9 Biliary tract, unspecified
0.063 0.936 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.936 0.063
Z50 Care involving use of rehabilitation procedures
0.000 0.937 0.063
K90-K93 Other diseases of the digestive system
0.000 0.937 0.063
C06.0 Cheek mucosa
0.063 0.937 0.000
C15.8 Overlapping lesion of oesophagus
0.063 0.937 0.000
C15.2 Abdominal part of oesophagus
0.063 0.937 0.000
C15.1 Thoracic part of oesophagus
0.063 0.937 0.000
C15.0 Cervical part of oesophagus
0.063 0.937 0.000
C02.8 Overlapping lesion of tongue
0.062 0.938 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.062 0.938 0.000
C02.2 Ventral surface of tongue
0.062 0.938 0.000
C02.0 Dorsal surface of tongue
0.062 0.938 0.000
C06.2 Retromolar area
0.062 0.938 0.000
Z50.1 Other physical therapy
0.000 0.938 0.062
C25.0 Head of pancreas
0.062 0.938 0.000
C05.9 Palate, unspecified
0.061 0.939 0.000
C05.8 Overlapping lesion of palate
0.061 0.939 0.000
C05.2 Uvula
0.061 0.939 0.000
C05.0 Hard palate
0.061 0.939 0.000
C16.5 Lesser curvature of stomach, unspecified
0.061 0.939 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.939 0.061
C14.8 Overlapping lesion of lip, oral cavity and pharynx
0.061 0.939 0.000
C14.2 Waldeyer's ring
0.061 0.939 0.000
E73.8 Other lactose intolerance
0.000 0.939 0.061
E73.1 Secondary lactase deficiency
0.000 0.939 0.061
E73.0 Congenital lactase deficiency
0.000 0.939 0.061
D03 Melanoma in situ
0.061 0.939 0.000
C69.3 Choroid
0.060 0.940 0.000
C16.8 Overlapping lesion of stomach
0.060 0.940 0.000
C16.4 Pylorus
0.060 0.940 0.000
C16.2 Body of stomach
0.060 0.940 0.000
C16.1 Fundus of stomach
0.060 0.940 0.000
C25.1 Body of pancreas
0.060 0.940 0.000
C16.6 Greater curvature of stomach, unspecified
0.060 0.940 0.000
C02.9 Tongue, unspecified
0.059 0.941 0.000
C10.9 Oropharynx, unspecified
0.059 0.941 0.000
C80 Malignant neoplasm without specification of site
0.059 0.941 0.000
C70.9 Meninges, unspecified
0.059 0.941 0.000
C70.1 Spinal meninges
0.059 0.941 0.000
C70.0 Cerebral meninges
0.059 0.941 0.000
C72.9 Central nervous system, unspecified
0.059 0.941 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.059 0.941 0.000
C72.5 Other and unspecified cranial nerves
0.059 0.941 0.000
C72.4 Acoustic nerve
0.059 0.941 0.000
C72.3 Optic nerve
0.059 0.941 0.000
C72.2 Olfactory nerve
0.059 0.941 0.000
C72.1 Cauda equina
0.059 0.941 0.000
C72.0 Spinal cord
0.059 0.941 0.000
C45 Mesothelioma
0.059 0.941 0.000
C51-C58 Malignant neoplasms of female genital organs
0.058 0.942 0.000
E80.2 Other porphyria
0.000 0.942 0.058
C09 Malignant neoplasm of tonsil
0.058 0.942 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.058 0.942 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.058 0.942 0.000
C06.9 Mouth, unspecified
0.058 0.942 0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.058 0.942 0.000
C06.1 Vestibule of mouth
0.058 0.942 0.000
C15.9 Oesophagus, unspecified
0.058 0.942 0.000
C16.3 Pyloric antrum
0.058 0.942 0.000
C69.8 Overlapping lesion of eye and adnexa
0.057 0.943 0.000
C69.6 Orbit
0.057 0.943 0.000
C69.5 Lachrymal gland and duct
0.057 0.943 0.000
C69.4 Ciliary body
0.057 0.943 0.000
C69.2 Retina
0.057 0.943 0.000
C69.1 Cornea
0.057 0.943 0.000
C69.0 Conjunctiva
0.057 0.943 0.000
E86 Volume depletion
0.000 0.943 0.057
D03.6 Melanoma in situ of upper limb, including shoulder
0.057 0.943 0.000
D09 Carcinoma in situ of other and unspecified sites
0.056 0.944 0.000
D04 Carcinoma in situ of skin
0.056 0.944 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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