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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2273017
log Bayes Factor = 201.258
Chromosome 6   position 32,337,630  (GRCh37) Explore rs2273017 on Ensembl!
Variant rs2273017 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.003 0.997
M07 Psoriatic and enteropathic arthropathies
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.004 0.996
G37 Other demyelinating diseases of central nervous system
0.996 0.004 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.004 0.996
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
M35.3 Polymyalgia rheumatica
0.000 0.004 0.996
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.005 0.995
G37.9 Demyelinating disease of central nervous system, unspecified
0.995 0.005 0.000
M07.3 Other psoriatic arthropathies
0.000 0.006 0.994
H30-H36 Disorders of choroid and retina
0.000 0.007 0.993
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.008 0.992
M35 Other systemic involvement of connective tissue
0.000 0.009 0.991
# Top node
0.000 0.009 0.991
M20-M25 Other joint disorders
0.000 0.010 0.990
E11.1 With ketoacidosis
0.000 0.011 0.989
J33.8 Other polyp of sinus
0.000 0.012 0.988
E10.2 With renal complications
0.000 0.012 0.988
Chapter VII Diseases of the eye and adnexa
0.000 0.013 0.987
E10.5 With peripheral circulatory complications
0.000 0.013 0.987
Chapter X Diseases of the respiratory system
0.000 0.016 0.984
J45 Asthma
0.000 0.017 0.983
J40-J47 Chronic lower respiratory diseases
0.000 0.019 0.981
L40-L45 Papulosquamous disorders
0.000 0.024 0.976
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.026 0.974
E11.3 With ophthalmic complications
0.000 0.027 0.973
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.029 0.971
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.029 0.971
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.030 0.970
E06 Thyroiditis
0.000 0.031 0.969
J30-J39 Other diseases of upper respiratory tract
0.000 0.034 0.966
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.034 0.966
E10.0 With coma
0.000 0.039 0.961
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.043 0.957
M31 Other necrotising vasculopathies
0.000 0.044 0.956
M06.3 Rheumatoid nodule
0.000 0.046 0.954
L40.0 Psoriasis vulgaris
0.000 0.052 0.948
M06.4 Inflammatory polyarthropathy
0.000 0.060 0.940
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.061 0.939
E06.3 Autoimmune thyroiditis
0.000 0.062 0.938
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.063 0.937
E11.2 With renal complications
0.000 0.070 0.930
D64.9 Anaemia, unspecified
0.000 0.070 0.930
M31.6 Other giant cell arteritis
0.000 0.071 0.929
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.071 0.929
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.074 0.926
D64 Other anaemias
0.000 0.076 0.924
D60-D64 Aplastic and other anaemias
0.000 0.077 0.923
J43 Emphysema
0.000 0.081 0.919
M34 Systemic sclerosis
0.000 0.086 0.914
E10.8 With unspecified complications
0.000 0.087 0.913
E83 Disorders of mineral metabolism
0.894 0.087 0.019
H53-H54 Visual disturbances and blindness
0.000 0.102 0.898
H34 Retinal vascular occlusions
0.000 0.102 0.898
J86 Pyothorax
0.000 0.104 0.896
E10.6 With other specified complications
0.000 0.111 0.889
M45-M49 Spondylopathies
0.000 0.111 0.889
M35.1 Other overlap syndromes
0.000 0.117 0.883
H54 Blindness and low vision
0.000 0.123 0.877
G37.8 Other specified demyelinating diseases of central nervous system
0.874 0.126 0.000
E11.8 With unspecified complications
0.000 0.128 0.872
E50-E64 Other nutritional deficiencies
0.000 0.130 0.870
J95-J99 Other diseases of the respiratory system
0.000 0.130 0.870
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.134 0.866
E14.6 With other specified complications
0.000 0.139 0.861
D50-D53 Nutritional anaemias
0.000 0.152 0.848
E83.5 Disorders of calcium metabolism
0.848 0.152 0.000
M45 Ankylosing spondylitis
0.000 0.157 0.843
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.159 0.841
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.162 0.838
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.164 0.836
M49 Spondylopathies in diseases classified elsewhere
0.000 0.166 0.834
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.166 0.834
H54.7 Unspecified visual loss
0.000 0.168 0.832
E53 Deficiency of other B group vitamins
0.000 0.168 0.832
K90 Intestinal malabsorption
0.000 0.169 0.831
J39 Other diseases of upper respiratory tract
0.000 0.171 0.829
J95.0 Tracheostomy malfunction
0.000 0.171 0.829
E14.1 With ketoacidosis
0.000 0.171 0.829
M65-M68 Disorders of synovium and tendon
0.000 0.172 0.828
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.176 0.824
J86.9 Pyothorax without fistula
0.000 0.177 0.823
J86.0 Pyothorax with fistula
0.000 0.178 0.822
L40.1 Generalised pustular psoriasis
0.000 0.178 0.822
L40.8 Other psoriasis
0.000 0.183 0.817
M12 Other specific arthropathies
0.000 0.184 0.816
D50 Iron deficiency anaemia
0.000 0.186 0.814
E53.8 Deficiency of other specified B group vitamins
0.000 0.187 0.813
M24 Other specific joint derangements
0.000 0.187 0.813
E16.1 Other hypoglycaemia
0.000 0.191 0.809
D50.9 Iron deficiency anaemia, unspecified
0.000 0.192 0.808
H20 Iridocyclitis
0.000 0.192 0.808
H33 Retinal detachments and breaks
0.000 0.192 0.808
H43-H45 Disorders of vitreous body and globe
0.000 0.193 0.807
E03.8 Other specified hypothyroidism
0.000 0.195 0.805
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.199 0.801
E14.8 With unspecified complications
0.000 0.200 0.800
E83.3 Disorders of phosphorus metabolism
0.795 0.201 0.004
M06.34 Rheumatoid nodule (Hand)
0.000 0.201 0.799
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.204 0.796
H54.0 Blindness, both eyes
0.000 0.206 0.794
E27 Other disorders of adrenal gland
0.000 0.207 0.793
E20-E35 Disorders of other endocrine glands
0.000 0.209 0.791
J43.2 Centrilobular emphysema
0.000 0.211 0.789
E27.1 Primary adrenocortical insufficiency
0.000 0.214 0.786
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.215 0.785
E14.2 Withrenal complications
0.000 0.216 0.784
M34.1 CR(E)ST syndrome
0.000 0.216 0.784
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.217 0.783
H33.3 Retinal breaks without detachment
0.000 0.218 0.782
H20.0 Acute and subacute iridocyclitis
0.000 0.221 0.779
L10-L14 Bullous disorders
0.000 0.222 0.778
J33.1 Polypoid sinus degeneration
0.000 0.222 0.778
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.222 0.778
J43.9 Emphysema, unspecified
0.000 0.222 0.778
M24.1 Other articular cartilage disorders
0.000 0.223 0.777
E83.9 Disorder of mineral metabolism, unspecified
0.759 0.231 0.010
J46 Status asthmaticus
0.000 0.233 0.767
H34.2 Other retinal artery occlusions
0.000 0.238 0.761
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.241 0.759
J39.8 Other specified diseases of upper respiratory tract
0.000 0.242 0.758
J20-J22 Other acute lower respiratory infections
0.000 0.244 0.756
H34.9 Retinal vascular occlusion, unspecified
0.000 0.245 0.755
J43.8 Other emphysema
0.000 0.245 0.755
E11.5 With peripheral circulatory complications
0.000 0.245 0.755
G36 Other acute disseminated demyelination
0.754 0.245 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.248 0.752
M34.8 Other forms of systemic sclerosis
0.000 0.248 0.752
E06.5 Other chronic thyroiditis
0.000 0.248 0.752
K90-K93 Other diseases of the digestive system
0.000 0.250 0.750
H33.4 Traction detachment of retina
0.000 0.250 0.750
E11.4 With neurological complications
0.000 0.251 0.749
M34.9 Systemic sclerosis, unspecified
0.000 0.252 0.748
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.252 0.748
Chapter XI Diseases of the digestive system
0.000 0.253 0.747
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.000 0.253 0.747
M31.3 Wegener's granulomatosis
0.000 0.256 0.744
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.258 0.742
H54.2 Low vision, both eyes
0.000 0.261 0.739
E07 Other disorders of thyroid
0.000 0.261 0.739
M65 Synovitis and tenosynovitis
0.000 0.264 0.736
K75 Other inflammatory liver diseases
0.000 0.265 0.735
K70-K77 Diseases of liver
0.000 0.265 0.735
H30 Chorioretinal inflammation
0.000 0.266 0.734
K75.4 Autoimmune hepatitis
0.000 0.268 0.732
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.268 0.731
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.270 0.730
L40.4 Guttate psoriasis
0.000 0.272 0.728
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.272 0.728
E06.9 Thyroiditis, unspecified
0.000 0.272 0.728
M31.7 Microscopic polyangiitis
0.000 0.272 0.728
M31.8 Other specified necrotising vasculopathies
0.000 0.273 0.727
M06.0 Seronegative rheumatoid arthritis
0.000 0.273 0.727
Chapter VIII Diseases of the ear and mastoid process
0.000 0.273 0.727
H43 Disorders of vitreous body
0.000 0.277 0.723
M35.2 Behcet's disease
0.000 0.277 0.723
L40.3 Pustulosis palmaris et plantaris
0.000 0.281 0.719
E14.5 With peripheral circulatory complications
0.000 0.282 0.718
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
K90.9 Intestinal malabsorption, unspecified
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.285 0.714
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.285 0.714
M07.2 Psoriatic spondylitis
0.000 0.285 0.714
M07.1 Arthritis mutilans
0.000 0.285 0.714
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.285 0.714
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.286 0.714
M07.38 Other psoriatic arthropathies (Other)
0.000 0.287 0.713
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.287 0.713
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.287 0.713
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.288 0.712
M07.6 Other enteropathic arthropathies
0.000 0.289 0.711
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.289 0.711
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.289 0.711
M35.5 Multifocal fibrosclerosis
0.000 0.289 0.711
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.289 0.710
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.290 0.710
M35.7 Hypermobility syndrome
0.000 0.292 0.708
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.296 0.704
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.702 0.298 0.000
K75.8 Other specified inflammatory liver diseases
0.000 0.299 0.701
D62 Acute posthaemorrhagic anaemia
0.000 0.300 0.700
L44 Other papulosquamous disorders
0.000 0.300 0.699
L41 Parapsoriasis
0.000 0.300 0.699
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.300 0.699
H20.1 Chronic iridocyclitis
0.000 0.304 0.696
E06.4 Drug-induced thyroiditis
0.000 0.305 0.695
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.305 0.695
E06.1 Subacute thyroiditis
0.000 0.305 0.695
E06.0 Acute thyroiditis
0.000 0.305 0.695
L80 Vitiligo
0.000 0.308 0.692
E14.4 With neurological complications
0.000 0.308 0.692
M05.2 Rheumatoid vasculitis
0.000 0.309 0.691
H60-H62 Diseases of external ear
0.000 0.309 0.691
H35 Other retinal disorders
0.000 0.311 0.689
M06.1 Adult-onset Still's disease
0.000 0.311 0.689
H54.1 Blindness, one eye, low vision, other eye
0.000 0.312 0.688
M24.7 Protrusio acetabuli
0.000 0.313 0.686
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.314 0.686
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.315 0.685
M31.2 Lethal midline granuloma
0.000 0.315 0.685
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.316 0.684
M06.38 Rheumatoid nodule (Other)
0.000 0.316 0.684
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.316 0.684
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.316 0.684
M06.33 Rheumatoid nodule (Forearm)
0.000 0.316 0.684
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.316 0.684
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.316 0.684
M24.11 Other articular cartilage disorders (Shoulder region)
0.000 0.316 0.684
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)
0.000 0.322 0.678
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.326 0.674
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.326 0.674
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.326 0.674
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.326 0.674
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.326 0.674
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.326 0.674
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.326 0.674
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.326 0.674
K73 Chronic hepatitis, not elsewhere classified
0.000 0.326 0.674
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.329 0.671
M31.1 Thrombotic microangiopathy
0.000 0.330 0.670
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.331 0.669
M12.3 Palindromic rheumatism
0.000 0.332 0.668
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.332 0.668
D64.4 Congenital dyserythropoietic anaemia
0.000 0.337 0.662
D64.3 Other sideroblastic anaemias
0.000 0.337 0.662
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.337 0.662
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.337 0.662
D64.0 Hereditary sideroblastic anaemia
0.000 0.337 0.662
M66 Spontaneous rupture of synovium and tendon
0.000 0.338 0.662
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.338 0.662
H34.1 Central retinal artery occlusion
0.000 0.338 0.662
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.340 0.660
J43.1 Panlobular emphysema
0.000 0.341 0.659
J43.0 MacLeod's syndrome
0.000 0.341 0.659
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.341 0.659
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.344 0.655
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.344 0.655
E83.8 Other disorders of mineral metabolism
0.641 0.346 0.014
E83.2 Disorders of zinc metabolism
0.641 0.346 0.014
E83.0 Disorders of copper metabolism
0.641 0.346 0.014
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.346 0.654
M30 Polyarteritis nodosa and related conditions
0.000 0.346 0.654
H34.8 Other retinal vascular occlusions
0.000 0.346 0.654
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.347 0.653
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.347 0.653
H54.5 Low vision, one eye
0.000 0.348 0.652
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.348 0.652
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.348 0.652
H35.4 Peripheral retinal degeneration
0.000 0.351 0.649
M06.8 Other specified rheumatoid arthritis
0.000 0.351 0.649
M34.0 Progressive systemic sclerosis
0.000 0.352 0.648
H15 Disorders of sclera
0.000 0.353 0.647
M91-M94 Chondropathies
0.000 0.354 0.646
H61 Other disorders of external ear
0.000 0.354 0.646
E11.0 With coma
0.000 0.355 0.645
M60-M63 Disorders of muscles
0.000 0.355 0.644
J39.0 Retropharyngeal and parapharyngeal abscess
0.000 0.356 0.644
E56 Other vitamin deficiencies
0.000 0.356 0.644
H34.0 Transient retinal artery occlusion
0.000 0.356 0.644
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.357 0.643
L12 Pemphigoid
0.000 0.357 0.643
H43.1 Vitreous haemorrhage
0.000 0.357 0.643
H16 Keratitis
0.000 0.359 0.640
M14 Arthropathies in other diseases classified elsewhere
0.000 0.360 0.639
J45.1 Nonallergic asthma
0.000 0.361 0.639
K50-K52 Noninfective enteritis and colitis
0.012 0.366 0.622
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.000 0.366 0.634
J22 Unspecified acute lower respiratory infection
0.000 0.367 0.633
M00-M03 Infectious arthropathies
0.000 0.367 0.633
M24.6 Ankylosis of joint
0.000 0.367 0.632
E03.1 Congenital hypothyroidism without goitre
0.000 0.368 0.632
E51 Thiamine deficiency
0.000 0.368 0.632
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.370 0.630
H54.3 Unqualified visual loss, both eyes
0.000 0.371 0.629
D51 Vitamin B12 deficiency anaemia
0.000 0.372 0.628
E54 Ascorbic acid deficiency
0.000 0.375 0.624
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.376 0.623
E63 Other nutritional deficiencies
0.000 0.376 0.623
E50 Vitamin A deficiency
0.000 0.376 0.623
E60 Dietary zinc deficiency
0.000 0.376 0.623
E59 Dietary selenium deficiency
0.000 0.376 0.623
E52 Niacin deficiency [pellagra]
0.000 0.376 0.623
J96 Respiratory failure, not elsewhere classified
0.000 0.376 0.623
H20.9 Iridocyclitis, unspecified
0.000 0.377 0.623
M32 Systemic lupus erythematosus
0.000 0.377 0.622
M46 Other inflammatory spondylopathies
0.000 0.380 0.620
H35.8 Other specified retinal disorders
0.000 0.382 0.618
E05.8 Other thyrotoxicosis
0.000 0.383 0.617
H61.8 Other specified disorders of external ear
0.000 0.384 0.616
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.385 0.615
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.000 0.385 0.615
L13 Other bullous disorders
0.000 0.386 0.614
M12.2 Villonodular synovitis (pigmented)
0.000 0.388 0.612
H54.6 Unqualified visual loss, one eye
0.000 0.388 0.612
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.389 0.611
H43.2 Crystalline deposits in vitreous body
0.000 0.389 0.611
D50.1 Sideropenic dysphagia
0.000 0.393 0.607
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.393 0.606
E40-E46 Malnutrition
0.000 0.394 0.606
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.396 0.604
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.396 0.604
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.396 0.604
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.396 0.604
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.396 0.604
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.396 0.604
M12.5 Traumatic arthropathy
0.000 0.397 0.602
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.398 0.602
M31.9 Necrotising vasculopathy, unspecified
0.000 0.399 0.601
K50 Crohn's disease [regional enteritis]
0.000 0.400 0.600
J95.5 Postprocedural subglottic stenosis
0.000 0.400 0.600
J95.4 Mendelson's syndrome
0.000 0.400 0.600
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.400 0.600
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.400 0.600
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.400 0.600
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.401 0.599
D53 Other nutritional anaemias
0.000 0.401 0.599
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.401 0.599
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.402 0.598
M49.4 Neuropathic spondylopathy
0.000 0.402 0.598
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.402 0.598
M49.2 Enterobacterial spondylitis
0.000 0.402 0.598
M49.1 Brucella spondylitis
0.000 0.402 0.598
M49.0 Tuberculosis of spine
0.000 0.402 0.598
M24.0 Loose body in joint
0.000 0.402 0.597
E53.1 Pyridoxine deficiency
0.000 0.403 0.597
E53.0 Riboflavin deficiency
0.000 0.403 0.597
J41 Simple and mucopurulent chronic bronchitis
0.000 0.403 0.596
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.404 0.596
K90.3 Pancreatic steatorrhoea
0.000 0.404 0.596
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.404 0.596
K90.1 Tropical sprue
0.000 0.404 0.596
M24.75 Protrusio acetabuli-Pelvic/thigh
0.000 0.404 0.596
J37 Chronic laryngitis and laryngotracheitis
0.000 0.404 0.596
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified
0.000 0.405 0.595
J39.1 Other abscess of pharynx
0.000 0.405 0.594
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.406 0.594
E24 Cushing's syndrome
0.000 0.409 0.591
E70-E90 Metabolic disorders
0.005 0.409 0.585
K74 Fibrosis and cirrhosis of liver
0.000 0.412 0.588
D55-D59 Haemolytic anaemias
0.000 0.413 0.587
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.415 0.585
M12.4 Intermittent hydrarthrosis
0.000 0.415 0.585
M12.1 Kaschin-Beck disease
0.000 0.415 0.585
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.415 0.585
L84 Corns and callosities
0.000 0.416 0.584
M24.9 Joint derangement, unspecified
0.000 0.417 0.583
G36.0 Neuromyelitis optica [Devic]
0.581 0.419 0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.000 0.419 0.580
H20.2 Lens-induced iridocyclitis
0.000 0.421 0.579
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.421 0.578
M35.8 Other specified systemic involvement of connective tissue
0.000 0.422 0.578
E28 Ovarian dysfunction
0.000 0.423 0.577
H60 Otitis externa
0.000 0.423 0.577
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.000 0.426 0.574
E13 Other specified diabetes mellitus
0.000 0.426 0.574
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.427 0.573
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.429 0.571
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)
0.000 0.429 0.570
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.429 0.570
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)
0.000 0.429 0.570
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)
0.000 0.429 0.570
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)
0.000 0.429 0.570
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)
0.000 0.429 0.570
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.429 0.570
E07.8 Other specified disorders of thyroid
0.000 0.430 0.570
H35.2 Other proliferative retinopathy
0.000 0.431 0.569
E27.5 Adrenomedullary hyperfunction
0.000 0.432 0.568
E27.0 Other adrenocortical overactivity
0.000 0.432 0.568
E27.8 Other specified disorders of adrenal gland
0.000 0.432 0.568
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.433 0.567
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.433 0.567
E32 Diseases of thymus
0.000 0.433 0.567
E31 Polyglandular dysfunction
0.000 0.433 0.567
E30 Disorders of puberty, not elsewhere classified
0.000 0.433 0.567
K50.1 Crohn's disease of large intestine
0.000 0.434 0.566
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.435 0.565
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.435 0.565
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.435 0.564
H30.9 Chorioretinal inflammation, unspecified
0.000 0.438 0.562
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.438 0.562
H54.9 Unspecified visual impairment (binocular)
0.000 0.440 0.560
J45.8 Mixed asthma
0.000 0.441 0.559
M66.0 Rupture of popliteal cyst
0.000 0.441 0.559
L14 Bullous disorders in diseases classified elsewhere
0.000 0.442 0.558
M24.19 Other articular cartilage disorders (Site unspecified)
0.000 0.443 0.557
M24.18 Other articular cartilage disorders (Other)
0.000 0.443 0.557
M24.14 Other articular cartilage disorders (Hand)
0.000 0.443 0.557
M24.12 Other articular cartilage disorders (Upper arm)
0.000 0.443 0.557
M24.10 Other articular cartilage disorders (Multiple sites)
0.000 0.443 0.557
H21 Other disorders of iris and ciliary body
0.000 0.443 0.557
J85 Abscess of lung and mediastinum
0.000 0.444 0.556
M31.0 Hypersensitivity angiitis
0.000 0.446 0.554
M24.5 Contracture of joint
0.000 0.447 0.553
H43.3 Other vitreous opacities
0.000 0.447 0.553
K50.8 Other Crohn's disease
0.000 0.448 0.552
H35.6 Retinal haemorrhage
0.000 0.448 0.552
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)
0.000 0.448 0.552
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.448 0.552
M24.4 Recurrent dislocation and subluxation of joint
0.000 0.449 0.551
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.452 0.548
L10 Pemphigus
0.000 0.453 0.547
K71 Toxic liver disease
0.000 0.455 0.545
M94 Other disorders of cartilage
0.000 0.458 0.542
L12.1 Cicatricial pemphigoid
0.000 0.458 0.542
E88 Other metabolic disorders
0.001 0.458 0.541
G36.9 Acute disseminated demyelination, unspecified
0.541 0.459 0.000
G36.8 Other specified acute disseminated demyelination
0.541 0.459 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.541 0.459 0.000
L90 Atrophic disorders of skin
0.000 0.459 0.541
K74.3 Primary biliary cirrhosis
0.000 0.459 0.541
E86 Volume depletion
0.000 0.460 0.540
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.462 0.538
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.000 0.464 0.536
M36.3 Arthropathy in other blood disorders
0.000 0.464 0.536
M36.2 Haemophilic arthropathy
0.000 0.464 0.536
M36.1 Arthropathy in neoplastic disease
0.000 0.464 0.536
M36.0 Dermato(poly)myositis in neoplastic disease
0.000 0.464 0.536
L92.0 Granuloma annulare
0.000 0.464 0.536
M13 Other arthritis
0.000 0.466 0.534
E61 Deficiency of other nutrient elements
0.000 0.468 0.532
J31.2 Chronic pharyngitis
0.000 0.468 0.532
E27.9 Disorder of adrenal gland, unspecified
0.000 0.468 0.532
L20-L30 Dermatitis and eczema
0.000 0.470 0.530

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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