TreeWAS – Variant ID: rs2273359

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M48.06 Spinal stenosis (Lumbar region)	0.246	0.754	0.000
M48.0 Spinal stenosis	0.246	0.754	0.000
M48 Other spondylopathies	0.237	0.763	0.000
M45-M49 Spondylopathies	0.231	0.769	0.000
M47 Spondylosis	0.230	0.770	0.000
M47.86 Other spondylosis (Lumbar region)	0.222	0.778	0.000
M47.8 Other spondylosis	0.222	0.778	0.000
M48.09 Spinal stenosis (Site unspecified)	0.218	0.782	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.210	0.790	0.000
M46 Other inflammatory spondylopathies	0.204	0.796	0.000
M47.9 Spondylosis, unspecified	0.202	0.798	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.184	0.816	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.182	0.818	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.181	0.819	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.176	0.824	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.176	0.824	0.000
M48.04 Spinal stenosis (Thoracic region)	0.176	0.824	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.176	0.824	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.176	0.824	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.176	0.824	0.000
M47.2 Other spondylosis with radiculopathy	0.176	0.824	0.000
M47.1 Other spondylosis with myelopathy	0.175	0.825	0.000
M48.9 Spondylopathy, unspecified	0.170	0.830	0.000
M48.8 Other specified spondylopathies	0.170	0.830	0.000
M48.4 Fatigue fracture of vertebra	0.170	0.830	0.000
M48.3 Traumatic spondylopathy	0.170	0.830	0.000
M48.2 Kissing spine	0.170	0.830	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.170	0.830	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.168	0.832	0.000
M49 Spondylopathies in diseases classified elsewhere	0.166	0.834	0.000
M48.02 Spinal stenosis (Cervical region)	0.166	0.834	0.000
M45 Ankylosing spondylitis	0.165	0.835	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.165	0.835	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.164	0.836	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.162	0.838	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.159	0.841	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.159	0.841	0.000
M47.84 Other spondylosis (Thoracic region)	0.159	0.841	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.159	0.841	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.159	0.841	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.155	0.845	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.154	0.846	0.000
M46.8 Other specified inflammatory spondylopathies	0.146	0.854	0.000
M46.5 Other infective spondylopathies	0.146	0.854	0.000
M46.4 Discitis, unspecified	0.146	0.854	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.146	0.854	0.000
M46.2 Osteomyelitis of vertebra	0.146	0.854	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.146	0.854	0.000
M46.0 Spinal enthesopathy	0.146	0.854	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.146	0.854	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.145	0.855	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.145	0.855	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.145	0.855	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.145	0.855	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.145	0.855	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.143	0.857	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.142	0.858	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.136	0.864	0.000
M47.89 Other spondylosis (Site unspecified)	0.134	0.866	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.132	0.868	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.132	0.868	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.132	0.868	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.132	0.868	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.132	0.868	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.132	0.868	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.132	0.868	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.131	0.869	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.127	0.873	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.127	0.873	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.126	0.874	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.126	0.874	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.126	0.874	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.126	0.874	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.126	0.874	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.126	0.874	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.126	0.874	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.125	0.874	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.125	0.874	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.125	0.874	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.125	0.874	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.125	0.874	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.125	0.874	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.125	0.874	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.125	0.874	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.125	0.874	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.122	0.878	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.122	0.878	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.122	0.878	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.122	0.878	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.122	0.878	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.122	0.878	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.122	0.878	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.122	0.878	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.122	0.878	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.122	0.878	0.000
M48.29 Kissing spine (Site unspecified)	0.122	0.878	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.122	0.878	0.000
M48.27 Kissing spine (Lumbosacral region)	0.122	0.878	0.000
M48.26 Kissing spine (Lumbar region)	0.122	0.878	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.122	0.878	0.000
M48.24 Kissing spine (Thoracic region)	0.122	0.878	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.122	0.878	0.000
M48.22 Kissing spine (Cervical region)	0.122	0.878	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.122	0.878	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.122	0.878	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.122	0.878	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.122	0.878	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.122	0.878	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.122	0.878	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.122	0.878	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.122	0.878	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.122	0.878	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.122	0.878	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.122	0.878	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.122	0.878	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.122	0.878	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.122	0.878	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.122	0.878	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.122	0.878	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.122	0.878	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.122	0.878	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.122	0.878	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.122	0.878	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.122	0.878	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.122	0.878	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.122	0.878	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.122	0.878	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.122	0.878	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.122	0.878	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.122	0.878	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.122	0.878	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.122	0.878	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.122	0.878	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.122	0.878	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.122	0.878	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.122	0.878	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.122	0.878	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.122	0.878	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.122	0.878	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.122	0.878	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.122	0.878	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.122	0.878	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.122	0.878	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.122	0.878	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.122	0.878	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.121	0.879	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.121	0.879	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.121	0.879	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.121	0.879	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.121	0.879	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.121	0.879	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.121	0.879	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.121	0.879	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.121	0.879	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.119	0.880	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.119	0.881	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.119	0.881	0.000
M49.4 Neuropathic spondylopathy	0.119	0.881	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.119	0.881	0.000
M49.2 Enterobacterial spondylitis	0.119	0.881	0.000
M49.1 Brucella spondylitis	0.119	0.881	0.000
M49.0 Tuberculosis of spine	0.119	0.881	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.118	0.881	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.118	0.881	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.118	0.881	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.118	0.881	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.118	0.881	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.118	0.881	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.118	0.881	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.118	0.881	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.118	0.881	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.118	0.881	0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.118	0.881	0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.118	0.881	0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.118	0.881	0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.118	0.881	0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.118	0.881	0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.118	0.881	0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.118	0.881	0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.118	0.881	0.000
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.118	0.881	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.118	0.882	0.000
M46.09 Spinal enthesopathy (Site unspecified)	0.105	0.895	0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.105	0.895	0.000
M46.07 Spinal enthesopathy (Lumbosacral region)	0.105	0.895	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.105	0.895	0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.105	0.895	0.000
M46.04 Spinal enthesopathy (Thoracic region)	0.105	0.895	0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.105	0.895	0.000
M46.02 Spinal enthesopathy (Cervical region)	0.105	0.895	0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.105	0.895	0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.105	0.895	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.105	0.895	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.105	0.895	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.105	0.895	0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.105	0.895	0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.105	0.895	0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.105	0.895	0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.105	0.895	0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.105	0.895	0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.105	0.895	0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.105	0.895	0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.105	0.895	0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.105	0.895	0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.105	0.895	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.105	0.895	0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.105	0.895	0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.105	0.895	0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.105	0.895	0.000
M46.22 Osteomyelitis of vertebra (Cervical region)	0.105	0.895	0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.105	0.895	0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.105	0.895	0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.105	0.895	0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.105	0.895	0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.105	0.895	0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.105	0.895	0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.105	0.895	0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.105	0.895	0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.105	0.895	0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.105	0.895	0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.105	0.895	0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.105	0.895	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.105	0.895	0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.105	0.895	0.000
M46.47 Discitis, unspecified (Lumbosacral region)	0.105	0.895	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.105	0.895	0.000
M46.45 Discitis, unspecified (Thoracolumbar region)	0.105	0.895	0.000
M46.44 Discitis, unspecified (Thoracic region)	0.105	0.895	0.000
M46.43 Discitis, unspecified (Cervicothoracic region)	0.105	0.895	0.000
M46.42 Discitis, unspecified (Cervical region)	0.105	0.895	0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.105	0.895	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.105	0.895	0.000
M46.59 Other infective spondylopathies (Site unspecified)	0.105	0.895	0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.105	0.895	0.000
M46.57 Other infective spondylopathies (Lumbosacral region)	0.105	0.895	0.000
M46.56 Other infective spondylopathies (Lumbar region)	0.105	0.895	0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.105	0.895	0.000
M46.54 Other infective spondylopathies (Thoracic region)	0.105	0.895	0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.105	0.895	0.000
M46.52 Other infective spondylopathies (Cervical region)	0.105	0.895	0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.105	0.895	0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.105	0.895	0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.105	0.895	0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.105	0.895	0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)	0.105	0.895	0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)	0.105	0.895	0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)	0.105	0.895	0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)	0.105	0.895	0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)	0.105	0.895	0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)	0.105	0.895	0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)	0.105	0.895	0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)	0.105	0.895	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.105	0.895	0.000
M49.09 Tuberculosis of spine (Site unspecified)	0.085	0.914	0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)	0.085	0.914	0.000
M49.07 Tuberculosis of spine (Lumbosacral region)	0.085	0.914	0.000
M49.06 Tuberculosis of spine (Lumbar region)	0.085	0.914	0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)	0.085	0.914	0.000
M49.04 Tuberculosis of spine (Thoracic region)	0.085	0.914	0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)	0.085	0.914	0.000
M49.02 Tuberculosis of spine (Cervical region)	0.085	0.914	0.000
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)	0.085	0.914	0.000
M49.00 Tuberculosis of spine (Multiple sites in spine)	0.085	0.914	0.000
M49.19 Brucella spondylitis (Site unspecified)	0.085	0.914	0.000
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)	0.085	0.914	0.000
M49.17 Brucella spondylitis (Lumbosacral region)	0.085	0.914	0.000
M49.16 Brucella spondylitis (Lumbar region)	0.085	0.914	0.000
M49.15 Brucella spondylitis (Thoracolumbar region)	0.085	0.914	0.000
M49.14 Brucella spondylitis (Thoracic region)	0.085	0.914	0.000
M49.13 Brucella spondylitis (Cervicothoracic region)	0.085	0.914	0.000
M49.12 Brucella spondylitis (Cervical region)	0.085	0.914	0.000
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)	0.085	0.914	0.000
M49.10 Brucella spondylitis (Multiple sites in spine)	0.085	0.914	0.000
M49.29 Enterobacterial spondylitis (Site unspecified)	0.085	0.914	0.000
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)	0.085	0.914	0.000
M49.27 Enterobacterial spondylitis (Lumbosacral region)	0.085	0.914	0.000
M49.26 Enterobacterial spondylitis (Lumbar region)	0.085	0.914	0.000
M49.25 Enterobacterial spondylitis (Thoracolumbar region)	0.085	0.914	0.000
M49.24 Enterobacterial spondylitis (Thoracic region)	0.085	0.914	0.000
M49.23 Enterobacterial spondylitis (Cervicothoracic region)	0.085	0.914	0.000
M49.22 Enterobacterial spondylitis (Cervical region)	0.085	0.914	0.000
M49.21 Enterobacterial spondylitis (Occipito-atlanto-axial region)	0.085	0.914	0.000
M49.20 Enterobacterial spondylitis (Multiple sites in spine)	0.085	0.914	0.000
M49.39 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Site unspecified)	0.085	0.914	0.000
M49.38 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Sacral and sacrococcygeal region)	0.085	0.914	0.000
M49.37 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbosacral region)	0.085	0.914	0.000
M49.36 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbar region)	0.085	0.914	0.000
M49.35 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracolumbar region)	0.085	0.914	0.000
M49.34 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracic region)	0.085	0.914	0.000
M49.33 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervicothoracic region)	0.085	0.914	0.000
M49.32 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervical region)	0.085	0.914	0.000
M49.31 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Occipito-atlanto-axial region)	0.085	0.914	0.000
M49.30 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Multiple sites in spine)	0.085	0.914	0.000
M49.49 Neuropathic spondylopathy (Site unspecified)	0.085	0.914	0.000
M49.48 Neuropathic spondylopathy (Sacral and sacrococcygeal region)	0.085	0.914	0.000
M49.47 Neuropathic spondylopathy (Lumbosacral region)	0.085	0.914	0.000
M49.46 Neuropathic spondylopathy (Lumbar region)	0.085	0.914	0.000
M49.45 Neuropathic spondylopathy (Thoracolumbar region)	0.085	0.914	0.000
M49.44 Neuropathic spondylopathy (Thoracic region)	0.085	0.914	0.000
M49.43 Neuropathic spondylopathy (Cervicothoracic region)	0.085	0.914	0.000
M49.42 Neuropathic spondylopathy (Cervical region)	0.085	0.914	0.000
M49.41 Neuropathic spondylopathy (Occipito-atlanto-axial region)	0.085	0.914	0.000
M49.40 Neuropathic spondylopathy (Multiple sites in spine)	0.085	0.914	0.000
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.085	0.914	0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.085	0.914	0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.085	0.914	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.085	0.914	0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.085	0.914	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.085	0.914	0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.085	0.914	0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.085	0.914	0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.085	0.914	0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.085	0.914	0.000
M49.89 Spondylopathy in other diseases classified elsewhere (Site unspecified)	0.085	0.914	0.000
M49.88 Spondylopathy in other diseases classified elsewhere (Sacral and sacrococcygeal region)	0.085	0.914	0.000
M49.87 Spondylopathy in other diseases classified elsewhere (Lumbosacral region)	0.085	0.914	0.000
M49.86 Spondylopathy in other diseases classified elsewhere (Lumbar region)	0.085	0.914	0.000
M49.85 Spondylopathy in other diseases classified elsewhere (Thoracolumbar region)	0.085	0.914	0.000
M49.84 Spondylopathy in other diseases classified elsewhere (Thoracic region)	0.085	0.914	0.000
M49.83 Spondylopathy in other diseases classified elsewhere (Cervicothoracic region)	0.085	0.914	0.000
M49.82 Spondylopathy in other diseases classified elsewhere (Cervical region)	0.085	0.914	0.000
M49.81 Spondylopathy in other diseases classified elsewhere (Occipito-atlanto-axial region)	0.085	0.914	0.000
M49.80 Spondylopathy in other diseases classified elsewhere (Multiple sites in spine)	0.085	0.914	0.000
M47.82 Other spondylosis (Cervical region)	0.073	0.927	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.025	0.975	0.000
M60-M63 Disorders of muscles	0.021	0.979	0.000
M80-M85 Disorders of bone density and structure	0.021	0.979	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.020	0.980	0.000
M91-M94 Chondropathies	0.019	0.981	0.000
M65-M68 Disorders of synovium and tendon	0.019	0.981	0.000
M20-M25 Other joint disorders	0.019	0.981	0.000
M86-M90 Other osteopathies	0.019	0.981	0.000
M25 Other joint disorders, not elsewhere classified	0.018	0.982	0.000
M62 Other disorders of muscle	0.018	0.982	0.000
M80 Osteoporosis with pathological fracture	0.018	0.982	0.000
M00-M03 Infectious arthropathies	0.018	0.982	0.000
M84 Disorders of continuity of bone	0.017	0.983	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.016	0.984	0.000
M62.8 Other specified disorders of muscle	0.016	0.984	0.000
M67 Other disorders of synovium and tendon	0.016	0.984	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.016	0.984	0.000
M25.8 Other specified joint disorders	0.016	0.984	0.000
M25.9 Joint disorder, unspecified	0.016	0.984	0.000
M15-M19 Arthrosis	0.016	0.984	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.016	0.984	0.000
M85 Other disorders of bone density and structure	0.016	0.984	0.000
M31 Other necrotising vasculopathies	0.016	0.984	0.000
M90 Osteopathies in diseases classified elsewhere	0.016	0.984	0.000
M40-M43 Deforming dorsopathies	0.016	0.984	0.000
M34 Systemic sclerosis	0.016	0.984	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.015	0.985	0.000
M61 Calcification and ossification of muscle	0.015	0.985	0.000
M60 Myositis	0.015	0.985	0.000
M83 Adult osteomalacia	0.015	0.985	0.000
M82 Osteoporosis in diseases classified elsewhere	0.015	0.985	0.000
M93 Other osteochondropathies	0.015	0.985	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.015	0.985	0.000
N20.1 Calculus of ureter	0.000	0.985	0.015
M19.0 Primary arthrosis of other joints	0.015	0.985	0.000
M19 Other arthrosis	0.015	0.985	0.000
M99 Biomechanical lesions, not elsewhere classified	0.014	0.986	0.000
M84.0 Malunion of fracture	0.014	0.986	0.000
M24 Other specific joint derangements	0.014	0.986	0.000
M25.7 Osteophyte	0.014	0.986	0.000
F32 Depressive episode	0.014	0.986	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.014	0.986	0.000
M22 Disorders of patella	0.014	0.986	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.014	0.986	0.000
M88 Paget's disease of bone [osteitis deformans]	0.014	0.986	0.000
M92 Other juvenile osteochondrosis	0.014	0.986	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.014	0.986	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.014	0.986	0.000
M25.94 Joint disorder, unspecified (Hand)	0.014	0.986	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.014	0.986	0.000
M66 Spontaneous rupture of synovium and tendon	0.014	0.986	0.000
M67.1 Other contracture of tendon (sheath)	0.014	0.986	0.000
M25.0 Haemarthrosis	0.014	0.986	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.014	0.986	0.000
M33 Dermatopolymyositis	0.014	0.986	0.000
M32 Systemic lupus erythematosus	0.014	0.986	0.000
M30 Polyarteritis nodosa and related conditions	0.014	0.986	0.000
M25.3 Other instability of joint	0.014	0.986	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.014	0.986	0.000
F32.9 Depressive episode, unspecified	0.014	0.986	0.000
M90.7 Fracture of bone in neoplastic disease	0.014	0.986	0.000
M31.6 Other giant cell arteritis	0.014	0.986	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.014	0.986	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.014	0.986	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.013	0.986	0.000
M25.4 Effusion of joint	0.013	0.987	0.000
M25.2 Flail joint	0.013	0.987	0.000
M25.1 Fistula of joint	0.013	0.987	0.000
M34.9 Systemic sclerosis, unspecified	0.013	0.987	0.000
M62.9 Disorder of muscle, unspecified	0.013	0.987	0.000
M62.6 Muscle strain	0.013	0.987	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.013	0.987	0.000
M62.4 Contracture of muscle	0.013	0.987	0.000
M62.3 Immobility syndrome (paraplegic)	0.013	0.987	0.000
M62.2 Ischaemic infarction of muscle	0.013	0.987	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.013	0.987	0.000
M62.0 Diastasis of muscle	0.013	0.987	0.000
M94 Other disorders of cartilage	0.013	0.987	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.013	0.987	0.000
M89 Other disorders of bone	0.013	0.987	0.000
M87 Osteonecrosis	0.013	0.987	0.000
M80.8 Other osteoporosis with pathological fracture	0.013	0.987	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.013	0.987	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.013	0.987	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.013	0.987	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.013	0.987	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.013	0.987	0.000
M67.8 Other specified disorders of synovium and tendon	0.013	0.987	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.013	0.987	0.000
M02 Reactive arthropathies	0.013	0.987	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.013	0.987	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.013	0.987	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.013	0.987	0.000
M00 Pyogenic arthritis	0.013	0.987	0.000
M18 Arthrosis of first carpometacarpal joint	0.013	0.987	0.000
M84.03 Malunion of fracture (Forearm)	0.013	0.987	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.013	0.987	0.000
M25.5 Pain in joint	0.013	0.987	0.000
M81 Osteoporosis without pathological fracture	0.012	0.987	0.000
M25.74 Osteophyte (Hand)	0.012	0.987	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.012	0.988	0.000
M93.9 Osteochondropathy, unspecified	0.012	0.988	0.000
F31 Bipolar affective disorder	0.012	0.988	0.000
M25.84 Other specified joint disorders (Hand)	0.012	0.988	0.000
F30-F39 Mood [affective] disorders	0.012	0.988	0.000
M15 Polyarthrosis	0.012	0.988	0.000
M25.78 Osteophyte (Other)	0.012	0.988	0.000
M84.9 Disorder of continuity of bone, unspecified	0.012	0.988	0.000
M84.8 Other disorders of continuity of bone	0.012	0.988	0.000
M84.4 Pathological fracture, not elsewhere classified	0.012	0.988	0.000
M84.3 Stress fracture, not elsewhere classified	0.012	0.988	0.000
M84.2 Delayed union of fracture	0.012	0.988	0.000
M86 Osteomyelitis	0.012	0.988	0.000
M85.8 Other specified disorders of bone density and structure	0.012	0.988	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.012	0.988	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.012	0.988	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.012	0.988	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.012	0.988	0.000
M96.5 Postradiation scoliosis	0.012	0.988	0.000
M96.4 Postsurgical lordosis	0.012	0.988	0.000
M96.3 Postlaminectomy kyphosis	0.012	0.988	0.000
M96.2 Postradiation kyphosis	0.012	0.988	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.012	0.988	0.000
M67.4 Ganglion	0.012	0.988	0.000
M67.3 Transient synovitis	0.012	0.988	0.000
M67.0 Short Achilles tendon (acquired)	0.012	0.988	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.012	0.988	0.000
M62.88 Other specified disorders of muscle (Other)	0.012	0.988	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.012	0.988	0.000
M62.84 Other specified disorders of muscle (Hand)	0.012	0.988	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.012	0.988	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.012	0.988	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.012	0.988	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.012	0.988	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.012	0.988	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.012	0.988	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.012	0.988	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.012	0.988	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.012	0.988	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.012	0.988	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.012	0.988	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.012	0.988	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.012	0.988	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.012	0.988	0.000
M25.88 Other specified joint disorders (Other)	0.012	0.988	0.000
M25.83 Other specified joint disorders (Forearm)	0.012	0.988	0.000
M25.82 Other specified joint disorders (Upper arm)	0.012	0.988	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.012	0.988	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.012	0.988	0.000
M24.2 Disorder of ligament	0.012	0.988	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.012	0.988	0.000
M25.98 Joint disorder, unspecified (Other)	0.012	0.988	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.012	0.988	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.012	0.988	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.012	0.988	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.012	0.988	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.012	0.988	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.012	0.988	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.012	0.988	0.000
F32.1 Moderate depressive episode	0.012	0.988	0.000
N20 Calculus of kidney and ureter	0.000	0.988	0.012
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.011	0.988	0.000
M22.8 Other disorders of patella	0.012	0.988	0.000
M85.9 Disorder of bone density and structure, unspecified	0.011	0.988	0.000
M85.6 Other cyst of bone	0.011	0.988	0.000
M85.5 Aneurysmal bone cyst	0.011	0.988	0.000
M85.4 Solitary bone cyst	0.011	0.988	0.000
M85.3 Osteitis condensans	0.011	0.988	0.000
M85.2 Hyperostosis of skull	0.011	0.988	0.000
M85.1 Skeletal fluorosis	0.011	0.988	0.000
M85.0 Fibrous dysplasia (monostotic)	0.011	0.988	0.000
M25.57 Pain in joint (Ankle and foot)	0.012	0.988	0.000
M31.9 Necrotising vasculopathy, unspecified	0.011	0.988	0.000
M31.8 Other specified necrotising vasculopathies	0.011	0.988	0.000
M31.7 Microscopic polyangiitis	0.011	0.988	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.011	0.988	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations