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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2275508
log Bayes Factor = 87.9766
Chromosome 6   position 28,094,731  (GRCh37) Explore rs2275508 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.999 0.001 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.999 0.001 0.000
E05.9 Thyrotoxicosis, unspecified
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
E16 Other disorders of pancreatic internal secretion
0.997 0.003 0.000
E16.2 Hypoglycaemia, unspecified
0.996 0.004 0.000
E14 Unspecified diabetes mellitus
0.990 0.010 0.000
K40 Inguinal hernia
0.000 0.013 0.987
E10.3 With ophthalmic complications
0.987 0.013 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.015 0.985
E20-E35 Disorders of other endocrine glands
0.966 0.034 0.000
N40 Hyperplasia of prostate
0.000 0.037 0.963
E10.1 With ketoacidosis
0.956 0.044 0.000
E27 Other disorders of adrenal gland
0.940 0.060 0.000
E14.9 Without complications
0.930 0.070 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.929 0.071 0.000
E27.1 Primary adrenocortical insufficiency
0.925 0.075 0.000
E23 Hypofunction and other disorders of pituitary gland
0.910 0.090 0.000
E14.3 With ophthalmic complications
0.895 0.105 0.000
E10.2 With renal complications
0.883 0.117 0.000
E03 Other hypothyroidism
0.875 0.125 0.000
E11 Non-insulin-dependent diabetes mellitus
0.874 0.126 0.000
E10.6 With other specified complications
0.870 0.130 0.000
E11.5 With peripheral circulatory complications
0.865 0.135 0.000
E23.2 Diabetes insipidus
0.850 0.150 0.000
K90 Intestinal malabsorption
0.834 0.165 0.001
E07 Other disorders of thyroid
0.830 0.170 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.825 0.175 0.000
E14.4 With neurological complications
0.816 0.184 0.000
E20 Hypoparathyroidism
0.812 0.188 0.000
E03.9 Hypothyroidism, unspecified
0.805 0.195 0.000
E10.5 With peripheral circulatory complications
0.793 0.207 0.000
E10.7 With multiple complications
0.780 0.220 0.000
E24 Cushing's syndrome
0.778 0.222 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.778 0.222 0.000
E14.6 With other specified complications
0.771 0.229 0.000
E10.0 With coma
0.770 0.230 0.000
E14.1 With ketoacidosis
0.770 0.230 0.000
E14.2 Withrenal complications
0.760 0.240 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.760 0.240 0.000
E11.3 With ophthalmic complications
0.757 0.243 0.000
E31 Polyglandular dysfunction
0.753 0.247 0.000
E10.4 With neurological complications
0.751 0.249 0.000
E23.0 Hypopituitarism
0.744 0.256 0.000
E27.2 Addisonian crisis
0.733 0.267 0.000
E14.5 With peripheral circulatory complications
0.730 0.270 0.000
K90.9 Intestinal malabsorption, unspecified
0.724 0.276 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.716 0.284 0.000
E00 Congenital iodine-deficiency syndrome
0.716 0.284 0.000
E05.5 Thyroid crisis or storm
0.716 0.284 0.000
E05.4 Thyrotoxicosis factitia
0.716 0.284 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.716 0.284 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.716 0.284 0.000
E11.6 With other specified complications
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.715 0.285 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.715 0.285 0.000
E16.4 Abnormal secretion of gastrin
0.715 0.285 0.000
E16.3 Increased secretion of glucagon
0.715 0.285 0.000
E14.7 With multiple complications
0.710 0.290 0.000
E14.0 With coma
0.710 0.290 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.292 0.708
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.292 0.708
E20.9 Hypoparathyroidism, unspecified
0.702 0.298 0.000
N40-N51 Diseases of male genital organs
0.000 0.300 0.700
E16.1 Other hypoglycaemia
0.699 0.301 0.000
E25 Adrenogenital disorders
0.697 0.303 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.693 0.307 0.000
E32 Diseases of thymus
0.693 0.307 0.000
E30 Disorders of puberty, not elsewhere classified
0.693 0.307 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.692 0.308 0.000
E07.8 Other specified disorders of thyroid
0.685 0.315 0.000
N42 Other disorders of prostate
0.000 0.320 0.680
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.324 0.676
E27.5 Adrenomedullary hyperfunction
0.674 0.326 0.000
E27.0 Other adrenocortical overactivity
0.674 0.326 0.000
E23.6 Other disorders of pituitary gland
0.664 0.336 0.000
E40-E46 Malnutrition
0.660 0.340 0.000
E24.2 Drug-induced Cushing's syndrome
0.660 0.340 0.000
N42.8 Other specified disorders of prostate
0.000 0.345 0.655
N41 Inflammatory diseases of prostate
0.000 0.347 0.653
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.652 0.348 0.000
E23.1 Drug-induced hypopituitarism
0.652 0.348 0.000
E27.9 Disorder of adrenal gland, unspecified
0.651 0.349 0.000
E14.8 With unspecified complications
0.642 0.358 0.000
E28 Ovarian dysfunction
0.640 0.360 0.000
E11.0 With coma
0.636 0.364 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.635 0.365 0.000
E07.9 Disorder of thyroid, unspecified
0.635 0.365 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.631 0.369 0.000
E05.8 Other thyrotoxicosis
0.630 0.370 0.000
E03.5 Myxoedema coma
0.627 0.373 0.000
E03.4 Atrophy of thyroid (acquired)
0.627 0.373 0.000
E03.3 Postinfectious hypothyroidism
0.627 0.373 0.000
E03.1 Congenital hypothyroidism without goitre
0.627 0.373 0.000
E11.7 With multiple complications
0.627 0.373 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.627 0.373 0.000
E23.7 Disorder of pituitary gland, unspecified
0.624 0.376 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.385 0.615
E10.8 With unspecified complications
0.612 0.388 0.000
E24.0 Pituitary-dependent Cushing's disease
0.604 0.396 0.000
E31.0 Autoimmune polyglandular failure
0.600 0.400 0.000
K90.3 Pancreatic steatorrhoea
0.598 0.401 0.001
K90.2 Blind loop syndrome, not elsewhere classified
0.598 0.401 0.001
K90.1 Tropical sprue
0.598 0.401 0.001
N41.0 Acute prostatitis
0.000 0.402 0.598
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.403 0.597
E07.1 Dyshormogenetic goitre
0.595 0.405 0.000
E07.0 Hypersecretion of calcitonin
0.595 0.405 0.000
N46 Male infertility
0.000 0.406 0.594
E29 Testicular dysfunction
0.590 0.409 0.000
E26 Hyperaldosteronism
0.590 0.410 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.411 0.589
K90.8 Other intestinal malabsorption
0.587 0.412 0.001
E50-E64 Other nutritional deficiencies
0.585 0.415 0.000
E20.8 Other hypoparathyroidism
0.582 0.418 0.000
E20.1 Pseudohypoparathyroidism
0.582 0.418 0.000
E20.0 Idiopathic hypoparathyroidism
0.582 0.418 0.000
E06 Thyroiditis
0.571 0.429 0.000
E24.8 Other Cushing's syndrome
0.558 0.442 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.558 0.442 0.000
E24.3 Ectopic ACTH syndrome
0.558 0.442 0.000
E24.1 Nelson's syndrome
0.558 0.442 0.000
E13 Other specified diabetes mellitus
0.557 0.442 0.000
N44 Torsion of testis
0.000 0.443 0.557
N42.0 Calculus of prostate
0.000 0.449 0.551
E03.8 Other specified hypothyroidism
0.547 0.452 0.000
E11.1 With ketoacidosis
0.542 0.458 0.000
E31.9 Polyglandular dysfunction, unspecified
0.540 0.460 0.000
E31.8 Other polyglandular dysfunction
0.540 0.460 0.000
E31.1 Polyglandular hyperfunction
0.540 0.460 0.000
N45 Orchitis and epididymitis
0.000 0.470 0.530
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.513 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.513 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.513 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.513 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.513 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.513 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.513 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.513 0.486 0.000
E34 Other endocrine disorders
0.506 0.493 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.504 0.496 0.000
E25.9 Adrenogenital disorder, unspecified
0.500 0.500 0.000
E25.8 Other adrenogenital disorders
0.500 0.500 0.000
E30.9 Disorder of puberty, unspecified
0.497 0.503 0.000
E30.8 Other disorders of puberty
0.497 0.503 0.000
E30.1 Precocious puberty
0.497 0.503 0.000
E30.0 Delayed puberty
0.497 0.503 0.000
E32.9 Disease of thymus, unspecified
0.497 0.503 0.000
E32.8 Other diseases of thymus
0.497 0.503 0.000
E32.1 Abscess of thymus
0.497 0.503 0.000
E32.0 Persistent hyperplasia of thymus
0.497 0.503 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.497 0.503 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.497 0.503 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.497 0.503 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.495 0.505 0.000
N42.3 Dysplasia of prostate
0.000 0.513 0.487
E44 Protein-energy malnutrition of moderate and mild degree
0.473 0.526 0.000
E45 Retarded development following protein-energy malnutrition
0.473 0.526 0.000
E43 Unspecified severe protein-energy malnutrition
0.473 0.526 0.000
E42 Marasmic kwashiorkor
0.473 0.526 0.000
E41 Nutritional marasmus
0.473 0.526 0.000
E40 Kwashiorkor
0.473 0.526 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.527 0.472
N42.2 Atrophy of prostate
0.000 0.528 0.472
N41.3 Prostatocystitis
0.000 0.532 0.468
N41.2 Abscess of prostate
0.000 0.532 0.468
E28.3 Primary ovarian failure
0.466 0.534 0.000
E11.8 With unspecified complications
0.463 0.536 0.000
E24.9 Cushing's syndrome, unspecified
0.462 0.538 0.000
E28.9 Ovarian dysfunction, unspecified
0.459 0.541 0.000
E28.8 Other ovarian dysfunction
0.459 0.541 0.000
E28.1 Androgen excess
0.459 0.541 0.000
E28.0 Oestrogen excess
0.459 0.541 0.000
N41.8 Other inflammatory diseases of prostate
0.000 0.555 0.445
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.443 0.557 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.560 0.440
E61 Deficiency of other nutrient elements
0.428 0.572 0.000
E29.9 Testicular dysfunction, unspecified
0.423 0.576 0.000
E29.8 Other testicular dysfunction
0.423 0.576 0.000
E29.0 Testicular hyperfunction
0.423 0.576 0.000
E26.9 Hyperaldosteronism, unspecified
0.423 0.577 0.000
E26.8 Other hyperaldosteronism
0.423 0.577 0.000
E26.1 Secondary hyperaldosteronism
0.423 0.577 0.000
E53 Deficiency of other B group vitamins
0.421 0.579 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.580 0.420
E64 Sequelae of malnutrition and other nutritional deficiencies
0.419 0.581 0.000
E63 Other nutritional deficiencies
0.419 0.581 0.000
E56 Other vitamin deficiencies
0.419 0.581 0.000
E50 Vitamin A deficiency
0.419 0.581 0.000
E60 Dietary zinc deficiency
0.419 0.581 0.000
E59 Dietary selenium deficiency
0.419 0.581 0.000
E54 Ascorbic acid deficiency
0.419 0.581 0.000
E52 Niacin deficiency [pellagra]
0.419 0.581 0.000
E46 Unspecified protein-energy malnutrition
0.416 0.583 0.000
E51 Thiamine deficiency
0.416 0.584 0.000
E06.5 Other chronic thyroiditis
0.414 0.586 0.000
E06.9 Thyroiditis, unspecified
0.413 0.587 0.000
E22 Hyperfunction of pituitary gland
0.413 0.587 0.000
E06.4 Drug-induced thyroiditis
0.409 0.590 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.409 0.590 0.000
E06.1 Subacute thyroiditis
0.409 0.590 0.000
E06.0 Acute thyroiditis
0.409 0.590 0.000
E58 Dietary calcium deficiency
0.406 0.593 0.000
E13.8 With unspecified complications
0.400 0.600 0.000
E13.7 With multiple complications
0.400 0.600 0.000
E13.6 With other specified complications
0.400 0.600 0.000
E13.5 With peripheral circulatory complications
0.400 0.600 0.000
E13.4 With neurological complications
0.400 0.600 0.000
E13.2 With renal complications
0.400 0.600 0.000
E13.1 With ketoacidosis
0.400 0.600 0.000
E13.0 With coma
0.400 0.600 0.000
E13.3 With ophthalmic complications
0.399 0.601 0.000
E28.2 Polycystic ovarian syndrome
0.397 0.603 0.000
E34.5 Androgen resistance syndrome
0.363 0.636 0.000
E34.4 Constitutional tall stature
0.363 0.636 0.000
E34.3 Short stature, not elsewhere classified
0.363 0.636 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.363 0.636 0.000
E34.1 Other hypersecretion of intestinal hormones
0.363 0.636 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.637 0.363
E34.8 Other specified endocrine disorders
0.356 0.644 0.000
E61.1 Iron deficiency
0.345 0.655 0.000
K40-K46 Hernia
0.000 0.655 0.345
N42.9 Disorder of prostate, unspecified
0.000 0.656 0.344
E11.2 With renal complications
0.342 0.658 0.000
E21.4 Other specified disorders of parathyroid gland
0.340 0.660 0.000
E44.1 Mild protein-energy malnutrition
0.339 0.660 0.000
E44.0 Moderate protein-energy malnutrition
0.339 0.660 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.661 0.339
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.661 0.339
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.661 0.339
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.672 0.328
E21.2 Other hyperparathyroidism
0.328 0.672 0.000
K41 Femoral hernia
0.000 0.673 0.327
E53.8 Deficiency of other specified B group vitamins
0.323 0.677 0.000
E29.1 Testicular hypofunction
0.321 0.679 0.000
E26.0 Primary hyperaldosteronism
0.320 0.680 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.318 0.682 0.000
N50 Other disorders of male genital organs
0.000 0.683 0.317
N41.1 Chronic prostatitis
0.000 0.685 0.315
N51.2 Balanitis in diseases classified elsewhere
0.000 0.690 0.309
E34.0 Carcinoid syndrome
0.309 0.691 0.000
E61.9 Deficiency of nutrient element, unspecified
0.307 0.693 0.000
E61.8 Deficiency of other specified nutrient elements
0.307 0.693 0.000
E61.7 Deficiency of multiple nutrient elements
0.307 0.693 0.000
E61.6 Vanadium deficiency
0.307 0.693 0.000
E61.5 Molybdenum deficiency
0.307 0.693 0.000
E61.4 Chromium deficiency
0.307 0.693 0.000
E61.3 Manganese deficiency
0.307 0.693 0.000
E61.0 Copper deficiency
0.307 0.693 0.000
N48 Other disorders of penis
0.000 0.698 0.302
E53.1 Pyridoxine deficiency
0.302 0.698 0.000
E53.0 Riboflavin deficiency
0.302 0.698 0.000
E50.9 Vitamin A deficiency, unspecified
0.301 0.699 0.000
E50.8 Other manifestations of vitamin A deficiency
0.301 0.699 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.301 0.699 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.301 0.699 0.000
E50.5 Vitamin A deficiency with night blindness
0.301 0.699 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.301 0.699 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.301 0.699 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.301 0.699 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.301 0.699 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.301 0.699 0.000
E56.9 Vitamin deficiency, unspecified
0.301 0.699 0.000
E56.8 Deficiency of other vitamins
0.301 0.699 0.000
E56.1 Deficiency of vitamin K
0.301 0.699 0.000
E56.0 Deficiency of vitamin E
0.301 0.699 0.000
E63.9 Nutritional deficiency, unspecified
0.301 0.699 0.000
E63.8 Other specified nutritional deficiencies
0.301 0.699 0.000
E63.1 Imbalance of constituents of food intake
0.301 0.699 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.301 0.699 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.301 0.699 0.000
E64.8 Sequelae of other nutritional deficiencies
0.301 0.699 0.000
E64.3 Sequelae of rickets
0.301 0.699 0.000
E64.2 Sequelae of vitamin C deficiency
0.301 0.699 0.000
E64.1 Sequelae of vitamin A deficiency
0.301 0.699 0.000
E64.0 Sequelae of protein-energy malnutrition
0.301 0.699 0.000
N43 Hydrocele and spermatocele
0.000 0.699 0.301
E51.9 Thiamine deficiency, unspecified
0.298 0.701 0.000
E51.8 Other manifestations of thiamine deficiency
0.298 0.701 0.000
E51.1 Beriberi
0.298 0.701 0.000
E55 Vitamin D deficiency
0.296 0.704 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.296 0.704 0.000
E22.8 Other hyperfunction of pituitary gland
0.296 0.704 0.000
E51.2 Wernicke's encephalopathy
0.295 0.704 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.705 0.295
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.712 0.288
E21.3 Hyperparathyroidism, unspecified
0.287 0.713 0.000
N48.4 Impotence of organic origin
0.000 0.719 0.281
E34.9 Endocrine disorder, unspecified
0.279 0.721 0.000
E53.9 Vitamin B deficiency, unspecified
0.277 0.723 0.000
N48.1 Balanoposthitis
0.000 0.725 0.275
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.272 0.728 0.000
N50.0 Atrophy of testis
0.000 0.729 0.271
E65-E68 Obesity and other hyperalimentation
0.268 0.732 0.000
N50.9 Disorder of male genital organs, unspecified
0.000 0.734 0.266
E61.2 Magnesium deficiency
0.264 0.736 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.263 0.737 0.000
E27.8 Other specified disorders of adrenal gland
0.259 0.738 0.002
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.740 0.260
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.740 0.260
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.740 0.260
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.743 0.257
E11.4 With neurological complications
0.256 0.743 0.000
K46 Unspecified abdominal hernia
0.000 0.746 0.254
E22.1 Hyperprolactinaemia
0.253 0.747 0.000
E06.3 Autoimmune thyroiditis
0.249 0.751 0.000
E13.9 Without complications
0.243 0.757 0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.765 0.234
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.765 0.234
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.765 0.234
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.765 0.234
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.773 0.227
N48.2 Other inflammatory disorders of penis
0.000 0.778 0.222
N43.2 Other hydrocele
0.000 0.784 0.216
N43.1 Infected hydrocele
0.000 0.784 0.216
N43.0 Encysted hydrocele
0.000 0.784 0.216
E55.0 Rickets, active
0.212 0.787 0.000
K43 Ventral hernia
0.000 0.788 0.212
E11.9 Without complications
0.205 0.795 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.797 0.203
N48.5 Ulcer of penis
0.000 0.800 0.200
K44 Diaphragmatic hernia
0.000 0.801 0.199
E67 Other hyperalimentation
0.192 0.807 0.000
E68 Sequelae of hyperalimentation
0.192 0.807 0.000
N48.3 Priapism
0.000 0.814 0.186
E04 Other non-toxic goitre
0.186 0.814 0.000
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.818 0.182
N49.2 Inflammatory disorders of scrotum
0.000 0.820 0.180
E22.0 Acromegaly and pituitary gigantism
0.172 0.827 0.001
N43.4 Spermatocele
0.000 0.828 0.171
N48.0 Leukoplakia of penis
0.000 0.829 0.170
E21.0 Primary hyperparathyroidism
0.165 0.835 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.836 0.164
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.837 0.162
K45 Other abdominal hernia
0.000 0.840 0.159
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.848 0.152
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.848 0.152
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.848 0.152
K43.4 Parastomal hernia with gangrene
0.000 0.848 0.152
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.848 0.152
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.848 0.152
K43.1 Ventral hernia with gangrene
0.000 0.848 0.152
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.857 0.143
K44.1 Diaphragmatic hernia with gangrene
0.000 0.857 0.142
E67.8 Other specified hyperalimentation
0.138 0.862 0.000
E67.3 Hypervitaminosis D
0.138 0.862 0.000
E67.2 Megavitamin-B6 syndrome
0.138 0.862 0.000
E67.1 Hypercarotenaemia
0.138 0.862 0.000
E67.0 Hypervitaminosis A
0.138 0.862 0.000
N39.0 Urinary tract infection, site not specified
0.000 0.863 0.137
K42 Umbilical hernia
0.000 0.863 0.137
E04.8 Other specified non-toxic goitre
0.133 0.867 0.000
K75.4 Autoimmune hepatitis
0.127 0.873 0.000
T39.1 4-Aminophenol derivatives
0.000 0.877 0.123
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.880 0.120
K75 Other inflammatory liver diseases
0.116 0.884 0.000
K45.1 Other specified abdominal hernia with gangrene
0.000 0.885 0.114
T39.0 Salicylates
0.000 0.888 0.112
N43.3 Hydrocele, unspecified
0.000 0.888 0.112
N48.6 Balanitis xerotica obliterans
0.000 0.889 0.111
K75.9 Inflammatory liver disease, unspecified
0.111 0.889 0.000
E04.0 Non-toxic diffuse goitre
0.108 0.891 0.000
K75.8 Other specified inflammatory liver diseases
0.109 0.891 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.894 0.106
E65 Localised adiposity
0.105 0.894 0.001
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.895 0.105
E04.1 Non-toxic single thyroid nodule
0.104 0.896 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.899 0.101
K42.1 Umbilical hernia with gangrene
0.000 0.901 0.098
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.902 0.098
N39 Other disorders of urinary system
0.000 0.903 0.097
E04.9 Non-toxic goitre, unspecified
0.095 0.905 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.907 0.093
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.907 0.092
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.000 0.910 0.089
E55.9 Vitamin D deficiency, unspecified
0.089 0.911 0.000
N39.9 Disorder of urinary system, unspecified
0.000 0.911 0.089
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.912 0.088
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.912 0.087
T39.4 Antirheumatics, not elsewhere classified
0.000 0.914 0.086
T39.2 Pyrazolone derivatives
0.000 0.914 0.086
E83 Disorders of mineral metabolism
0.004 0.917 0.079
K75.3 Granulomatous hepatitis, not elsewhere classified
0.083 0.917 0.000
K75.2 Nonspecific reactive hepatitis
0.083 0.917 0.000
K75.1 Phlebitis of portal vein
0.083 0.917 0.000
T42.4 Benzodiazepines
0.000 0.917 0.083
K90-K93 Other diseases of the digestive system
0.051 0.917 0.031
N48.9 Disorder of penis, unspecified
0.002 0.919 0.079
N39.8 Other specified disorders of urinary system
0.000 0.921 0.079
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.925 0.075
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.001 0.925 0.074
T50.8 Diagnostic agents
0.000 0.928 0.072
T50.7 Analeptics and opioid receptor antagonists
0.000 0.928 0.072
T50.5 Appetite depressants
0.000 0.928 0.072
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.928 0.072
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.928 0.072
T50.1 Loop [high-ceiling] diuretics
0.000 0.928 0.072
T50.0 Mineralocorticoids and their antagonists
0.000 0.928 0.072
N30-N39 Other diseases of urinary system
0.000 0.928 0.072
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.929 0.071
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.929 0.071
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.929 0.071
N39.2 Orthostatic proteinuria, unspecified
0.000 0.930 0.069
N32 Other disorders of bladder
0.000 0.931 0.069
M20.1 Hallux valgus (acquired)
0.000 0.931 0.069
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.931 0.069
N32.0 Bladder-neck obstruction
0.000 0.931 0.069
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.931 0.068
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.933 0.067
T50.4 Drugs affecting uric acid metabolism
0.000 0.933 0.067
T36 Poisoning by systemic antibiotics
0.000 0.933 0.067
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.933 0.067
T42.1 Iminostilbenes
0.000 0.933 0.067
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.934 0.066
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.934 0.066
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.935 0.065
N32.8 Other specified disorders of bladder
0.000 0.935 0.065
N48.8 Other specified disorders of penis
0.000 0.936 0.064
K42.9 Umbilical hernia without obstruction or gangrene
0.000 0.936 0.064
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.937 0.063
T42.2 Succinimides and oxazolidinediones
0.000 0.937 0.063
N39.1 Persistent proteinuria, unspecified
0.000 0.938 0.062
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.938 0.062
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.939 0.061
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.940 0.060
E83.9 Disorder of mineral metabolism, unspecified
0.003 0.940 0.057
E83.8 Other disorders of mineral metabolism
0.003 0.940 0.057
E83.2 Disorders of zinc metabolism
0.003 0.940 0.057
E83.0 Disorders of copper metabolism
0.003 0.940 0.057
K93 Disorders of other digestive organs in diseases classified elsewhere
0.037 0.941 0.023
T40.2 Other opioids
0.000 0.941 0.059
K42.0 Umbilical hernia with obstruction, without gangrene
0.000 0.941 0.058
N32.2 Vesical fistula, not elsewhere classified
0.000 0.942 0.058
N36 Other disorders of urethra
0.000 0.943 0.057
E83.3 Disorders of phosphorus metabolism
0.002 0.943 0.055
I83 Varicose veins of lower extremities
0.000 0.943 0.057
N34 Urethritis and urethral syndrome
0.000 0.943 0.057
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.943 0.057
T45.0 Antiallergic and antiemetic drugs
0.000 0.943 0.057
T42.3 Barbiturates
0.000 0.945 0.055
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.946 0.054
T45.8 Other primarily systemic and haematological agents
0.000 0.946 0.054
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.946 0.054
T45.6 Fibrinolysis-affecting drugs
0.000 0.946 0.054
T45.5 Anticoagulants
0.000 0.946 0.054
T45.4 Iron and its compounds
0.000 0.946 0.054
T45.3 Enzymes, not elsewhere classified
0.000 0.946 0.054
T45.2 Vitamins, not elsewhere classified
0.000 0.946 0.054
T42.0 Hydantoin derivatives
0.000 0.946 0.053
N36.3 Prolapsed urethral mucosa
0.000 0.946 0.054
Chapter XIV Diseases of the genitourinary system
0.000 0.946 0.054
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.947 0.053
N32.1 Vesicointestinal fistula
0.000 0.947 0.053
N37 Urethral disorders in diseases classified elsewhere
0.000 0.948 0.052
N33 Bladder disorders in diseases classified elsewhere
0.000 0.948 0.052
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.949 0.051
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.949 0.051
T37.5 Antiviral drugs
0.000 0.949 0.051
T37.4 Anthelminthics
0.000 0.949 0.051
T37.3 Other antiprotozoal drugs
0.000 0.949 0.051
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.949 0.051
T37.1 Antimycobacterial drugs
0.000 0.949 0.051
T37.0 Sulphonamides
0.000 0.949 0.051
T41.5 Therapeutic gases
0.000 0.949 0.051
T41.4 Anaesthetic, unspecified
0.000 0.949 0.051
T41.3 Local anaesthetics
0.000 0.949 0.051
T41.2 Other and unspecified general anaesthetics
0.000 0.949 0.051
T41.1 Intravenous anaesthetics
0.000 0.949 0.051
T41.0 Inhaled anaesthetics
0.000 0.949 0.051
T49.9 Topical agent, unspecified
0.000 0.949 0.051
T49.8 Other topical agents
0.000 0.949 0.051
T49.7 Dental drugs, topically applied
0.000 0.949 0.051
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.949 0.051
T49.5 Ophthalmological drugs and preparations
0.000 0.949 0.051
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.949 0.051
T49.3 Emollients, demulcents and protectants
0.000 0.949 0.051
T49.2 Local astringents and local detergents
0.000 0.949 0.051
T49.1 Antipruritics
0.000 0.949 0.051
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.949 0.051
N36.2 Urethral caruncle
0.000 0.949 0.051

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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