TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs2281389
log Bayes Factor = 5.73364
Chromosome 6   position 33,059,796  (GRCh37) Explore rs2281389 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.001 0.999
E10 Insulin-dependent diabetes mellitus
0.998 0.002 0.000
E10.9 Without complications
0.998 0.002 0.000
E10.5 With peripheral circulatory complications
0.981 0.019 0.000
E10.3 With ophthalmic complications
0.938 0.062 0.000
E10-E14 Diabetes mellitus
0.920 0.080 0.000
E11 Non-insulin-dependent diabetes mellitus
0.904 0.096 0.000
E11.4 With neurological complications
0.893 0.107 0.000
E10.4 With neurological complications
0.889 0.111 0.000
E10.1 With ketoacidosis
0.881 0.119 0.000
E10.2 With renal complications
0.829 0.171 0.000
E11.3 With ophthalmic complications
0.787 0.213 0.000
E11.5 With peripheral circulatory complications
0.784 0.216 0.000
E11.1 With ketoacidosis
0.718 0.282 0.000
E10.7 With multiple complications
0.716 0.284 0.000
E03 Other hypothyroidism
0.035 0.285 0.680
E10.0 With coma
0.700 0.300 0.000
E10.8 With unspecified complications
0.698 0.302 0.000
E11.2 With renal complications
0.678 0.322 0.000
E12 Malnutrition-related diabetes mellitus
0.659 0.341 0.000
E11.7 With multiple complications
0.648 0.352 0.000
E13 Other specified diabetes mellitus
0.642 0.357 0.000
E03.8 Other specified hypothyroidism
0.014 0.379 0.608
E11.6 With other specified complications
0.617 0.383 0.000
E11.8 With unspecified complications
0.580 0.420 0.000
E10.6 With other specified complications
0.550 0.449 0.000
E11.0 With coma
0.550 0.450 0.000
E14 Unspecified diabetes mellitus
0.531 0.469 0.000
E03.5 Myxoedema coma
0.025 0.487 0.487
E03.4 Atrophy of thyroid (acquired)
0.025 0.487 0.487
E03.3 Postinfectious hypothyroidism
0.025 0.487 0.487
E03.1 Congenital hypothyroidism without goitre
0.025 0.487 0.487
E03.0 Congenital hypothyroidism with diffuse goitre
0.025 0.487 0.487
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.024 0.500 0.476
E13.3 With ophthalmic complications
0.490 0.510 0.000
E12.9 Without complications
0.473 0.527 0.000
E12.8 With unspecified complications
0.473 0.527 0.000
E12.7 With multiple complications
0.473 0.527 0.000
E12.6 With other specified complications
0.473 0.527 0.000
E12.5 With peripheral circulatory complications
0.473 0.527 0.000
E12.4 With neurological complications
0.473 0.527 0.000
E12.3 With ophthalmic complications
0.473 0.527 0.000
E12.2 With renal complications
0.473 0.527 0.000
E12.1 With ketoacidosis
0.473 0.527 0.000
E12.0 With coma
0.473 0.527 0.000
E13.8 With unspecified complications
0.461 0.539 0.000
E13.7 With multiple complications
0.461 0.539 0.000
E13.6 With other specified complications
0.461 0.539 0.000
E13.5 With peripheral circulatory complications
0.461 0.539 0.000
E13.4 With neurological complications
0.461 0.539 0.000
E13.2 With renal complications
0.461 0.539 0.000
E13.1 With ketoacidosis
0.461 0.539 0.000
E13.0 With coma
0.461 0.539 0.000
E14.6 With other specified complications
0.411 0.589 0.000
E13.9 Without complications
0.406 0.594 0.000
E14.5 With peripheral circulatory complications
0.401 0.599 0.000
E14.2 Withrenal complications
0.399 0.601 0.000
E14.3 With ophthalmic complications
0.390 0.610 0.000
E14.7 With multiple complications
0.381 0.619 0.000
E14.1 With ketoacidosis
0.381 0.619 0.000
E14.0 With coma
0.381 0.619 0.000
E14.4 With neurological complications
0.368 0.632 0.000
E14.8 With unspecified complications
0.363 0.636 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.338 0.661 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.311 0.688 0.000
E00-E07 Disorders of thyroid gland
0.280 0.703 0.017
E16 Other disorders of pancreatic internal secretion
0.292 0.708 0.000
E20-E35 Disorders of other endocrine glands
0.288 0.712 0.000
E27 Other disorders of adrenal gland
0.284 0.716 0.000
E16.2 Hypoglycaemia, unspecified
0.277 0.722 0.000
E04 Other non-toxic goitre
0.259 0.740 0.001
E27.4 Other and unspecified adrenocortical insufficiency
0.258 0.742 0.000
E27.8 Other specified disorders of adrenal gland
0.258 0.742 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.238 0.753 0.009
E04.2 Non-toxic multinodular goitre
0.246 0.754 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.239 0.760 0.000
E27.1 Primary adrenocortical insufficiency
0.239 0.761 0.000
E22 Hyperfunction of pituitary gland
0.236 0.764 0.000
E06 Thyroiditis
0.226 0.766 0.007
E23 Hypofunction and other disorders of pituitary gland
0.228 0.772 0.000
E15 Nondiabetic hypoglycaemic coma
0.223 0.776 0.000
E04.0 Non-toxic diffuse goitre
0.222 0.778 0.001
E25 Adrenogenital disorders
0.221 0.778 0.000
E16.1 Other hypoglycaemia
0.214 0.786 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.201 0.787 0.012
E00 Congenital iodine-deficiency syndrome
0.201 0.787 0.012
E16.0 Drug-induced hypoglycaemia without coma
0.212 0.788 0.000
E40-E46 Malnutrition
0.211 0.789 0.000
E22.0 Acromegaly and pituitary gigantism
0.210 0.790 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.210 0.790 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.210 0.790 0.000
E16.4 Abnormal secretion of gastrin
0.210 0.790 0.000
E16.3 Increased secretion of glucagon
0.210 0.790 0.000
E23.6 Other disorders of pituitary gland
0.209 0.790 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.206 0.793 0.000
E32 Diseases of thymus
0.206 0.793 0.000
E31 Polyglandular dysfunction
0.206 0.793 0.000
E30 Disorders of puberty, not elsewhere classified
0.206 0.793 0.000
E27.2 Addisonian crisis
0.205 0.794 0.000
E27.5 Adrenomedullary hyperfunction
0.204 0.796 0.000
E27.0 Other adrenocortical overactivity
0.204 0.796 0.000
E26 Hyperaldosteronism
0.194 0.806 0.000
E29 Testicular dysfunction
0.189 0.811 0.000
E20 Hypoparathyroidism
0.187 0.812 0.000
E04.8 Other specified non-toxic goitre
0.186 0.813 0.001
E06.9 Thyroiditis, unspecified
0.179 0.817 0.004
E04.1 Non-toxic single thyroid nodule
0.182 0.818 0.000
E06.3 Autoimmune thyroiditis
0.174 0.823 0.003
E07 Other disorders of thyroid
0.167 0.824 0.010
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.174 0.826 0.000
E24 Cushing's syndrome
0.172 0.828 0.000
E22.1 Hyperprolactinaemia
0.169 0.830 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.169 0.831 0.000
E22.8 Other hyperfunction of pituitary gland
0.169 0.831 0.000
E27.9 Disorder of adrenal gland, unspecified
0.169 0.831 0.000
E06.5 Other chronic thyroiditis
0.162 0.832 0.005
E06.4 Drug-induced thyroiditis
0.162 0.832 0.005
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.162 0.832 0.005
E06.1 Subacute thyroiditis
0.162 0.832 0.005
E06.0 Acute thyroiditis
0.162 0.832 0.005
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.164 0.836 0.000
E23.1 Drug-induced hypopituitarism
0.164 0.836 0.000
E50-E64 Other nutritional deficiencies
0.159 0.841 0.001
E25.9 Adrenogenital disorder, unspecified
0.159 0.841 0.000
E25.8 Other adrenogenital disorders
0.159 0.841 0.000
E23.0 Hypopituitarism
0.154 0.845 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.144 0.847 0.009
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.144 0.847 0.009
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.144 0.847 0.009
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.144 0.847 0.009
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.144 0.847 0.009
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.144 0.847 0.009
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.144 0.847 0.009
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.144 0.847 0.009
E34 Other endocrine disorders
0.152 0.847 0.001
E44 Protein-energy malnutrition of moderate and mild degree
0.151 0.848 0.000
E45 Retarded development following protein-energy malnutrition
0.151 0.848 0.000
E43 Unspecified severe protein-energy malnutrition
0.151 0.848 0.000
E42 Marasmic kwashiorkor
0.151 0.848 0.000
E41 Nutritional marasmus
0.151 0.848 0.000
E40 Kwashiorkor
0.151 0.848 0.000
E28 Ovarian dysfunction
0.151 0.849 0.000
E30.9 Disorder of puberty, unspecified
0.148 0.851 0.000
E30.8 Other disorders of puberty
0.148 0.851 0.000
E30.1 Precocious puberty
0.148 0.851 0.000
E30.0 Delayed puberty
0.148 0.851 0.000
E31.9 Polyglandular dysfunction, unspecified
0.148 0.851 0.000
E31.8 Other polyglandular dysfunction
0.148 0.851 0.000
E31.1 Polyglandular hyperfunction
0.148 0.851 0.000
E31.0 Autoimmune polyglandular failure
0.148 0.851 0.000
E32.9 Disease of thymus, unspecified
0.148 0.851 0.000
E32.8 Other diseases of thymus
0.148 0.851 0.000
E32.1 Abscess of thymus
0.148 0.851 0.000
E32.0 Persistent hyperplasia of thymus
0.148 0.851 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.148 0.851 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.148 0.851 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.148 0.851 0.000
E23.7 Disorder of pituitary gland, unspecified
0.141 0.858 0.000
E26.9 Hyperaldosteronism, unspecified
0.139 0.861 0.000
E26.8 Other hyperaldosteronism
0.139 0.861 0.000
E26.1 Secondary hyperaldosteronism
0.139 0.861 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.137 0.863 0.000
E29.9 Testicular dysfunction, unspecified
0.135 0.864 0.000
E29.8 Other testicular dysfunction
0.135 0.864 0.000
E29.0 Testicular hyperfunction
0.135 0.864 0.000
E20.8 Other hypoparathyroidism
0.134 0.865 0.000
E20.1 Pseudohypoparathyroidism
0.134 0.865 0.000
E20.0 Idiopathic hypoparathyroidism
0.134 0.865 0.000
E65-E68 Obesity and other hyperalimentation
0.133 0.866 0.000
E23.2 Diabetes insipidus
0.133 0.867 0.000
E24.0 Pituitary-dependent Cushing's disease
0.129 0.870 0.000
E07.1 Dyshormogenetic goitre
0.120 0.873 0.007
E07.0 Hypersecretion of calcitonin
0.120 0.873 0.007
E26.0 Primary hyperaldosteronism
0.126 0.874 0.000
E24.8 Other Cushing's syndrome
0.123 0.876 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.123 0.876 0.000
E24.3 Ectopic ACTH syndrome
0.123 0.876 0.000
E24.1 Nelson's syndrome
0.123 0.876 0.000
E14.9 Without complications
0.122 0.878 0.000
E46 Unspecified protein-energy malnutrition
0.119 0.881 0.000
E29.1 Testicular hypofunction
0.117 0.882 0.000
E20.9 Hypoparathyroidism, unspecified
0.115 0.884 0.001
E55 Vitamin D deficiency
0.115 0.885 0.000
E04.9 Non-toxic goitre, unspecified
0.114 0.885 0.001
E64 Sequelae of malnutrition and other nutritional deficiencies
0.114 0.886 0.001
E63 Other nutritional deficiencies
0.114 0.886 0.001
E56 Other vitamin deficiencies
0.114 0.886 0.001
E51 Thiamine deficiency
0.114 0.886 0.001
E50 Vitamin A deficiency
0.114 0.886 0.001
E60 Dietary zinc deficiency
0.114 0.886 0.001
E59 Dietary selenium deficiency
0.114 0.886 0.001
E58 Dietary calcium deficiency
0.114 0.886 0.001
E54 Ascorbic acid deficiency
0.114 0.886 0.001
E52 Niacin deficiency [pellagra]
0.114 0.886 0.001
E07.9 Disorder of thyroid, unspecified
0.109 0.887 0.004
E24.2 Drug-induced Cushing's syndrome
0.111 0.889 0.001
E34.8 Other specified endocrine disorders
0.109 0.890 0.001
E34.5 Androgen resistance syndrome
0.109 0.890 0.001
E34.4 Constitutional tall stature
0.109 0.890 0.001
E34.3 Short stature, not elsewhere classified
0.109 0.890 0.001
E34.2 Ectopic hormone secretion, not elsewhere classified
0.109 0.890 0.001
E34.1 Other hypersecretion of intestinal hormones
0.109 0.890 0.001
E44.1 Mild protein-energy malnutrition
0.108 0.891 0.000
E44.0 Moderate protein-energy malnutrition
0.108 0.891 0.000
E28.9 Ovarian dysfunction, unspecified
0.108 0.892 0.000
E28.8 Other ovarian dysfunction
0.108 0.892 0.000
E28.1 Androgen excess
0.108 0.892 0.000
E28.0 Oestrogen excess
0.108 0.892 0.000
E07.8 Other specified disorders of thyroid
0.100 0.892 0.008
E28.3 Primary ovarian failure
0.097 0.903 0.000
E24.9 Cushing's syndrome, unspecified
0.096 0.904 0.001
E67 Other hyperalimentation
0.096 0.904 0.000
E68 Sequelae of hyperalimentation
0.096 0.904 0.000
E34.0 Carcinoid syndrome
0.094 0.906 0.001
E70-E90 Metabolic disorders
0.092 0.908 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.087 0.911 0.002
E53 Deficiency of other B group vitamins
0.087 0.913 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.084 0.916 0.000
E55.9 Vitamin D deficiency, unspecified
0.083 0.916 0.000
E55.0 Rickets, active
0.082 0.917 0.000
E50.9 Vitamin A deficiency, unspecified
0.082 0.918 0.001
E50.8 Other manifestations of vitamin A deficiency
0.082 0.918 0.001
E50.7 Other ocular manifestations of vitamin A deficiency
0.082 0.918 0.001
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.082 0.918 0.001
E50.5 Vitamin A deficiency with night blindness
0.082 0.918 0.001
E50.4 Vitamin A deficiency with keratomalacia
0.082 0.918 0.001
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.082 0.918 0.001
E50.2 Vitamin A deficiency with corneal xerosis
0.082 0.918 0.001
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.082 0.918 0.001
E50.0 Vitamin A deficiency with conjunctival xerosis
0.082 0.918 0.001
E51.9 Thiamine deficiency, unspecified
0.082 0.918 0.001
E51.8 Other manifestations of thiamine deficiency
0.082 0.918 0.001
E51.2 Wernicke's encephalopathy
0.082 0.918 0.001
E51.1 Beriberi
0.082 0.918 0.001
E56.9 Vitamin deficiency, unspecified
0.082 0.918 0.001
E56.8 Deficiency of other vitamins
0.082 0.918 0.001
E56.1 Deficiency of vitamin K
0.082 0.918 0.001
E56.0 Deficiency of vitamin E
0.082 0.918 0.001
E63.9 Nutritional deficiency, unspecified
0.082 0.918 0.001
E63.8 Other specified nutritional deficiencies
0.082 0.918 0.001
E63.1 Imbalance of constituents of food intake
0.082 0.918 0.001
E63.0 Essential fatty acid [EFA] deficiency
0.082 0.918 0.001
E64.9 Sequelae of unspecified nutritional deficiency
0.082 0.918 0.001
E64.8 Sequelae of other nutritional deficiencies
0.082 0.918 0.001
E64.3 Sequelae of rickets
0.082 0.918 0.001
E64.2 Sequelae of vitamin C deficiency
0.082 0.918 0.001
E64.1 Sequelae of vitamin A deficiency
0.082 0.918 0.001
E64.0 Sequelae of protein-energy malnutrition
0.082 0.918 0.001
E34.9 Endocrine disorder, unspecified
0.080 0.919 0.001
E78.8 Other disorders of lipoprotein metabolism
0.080 0.920 0.000
E65 Localised adiposity
0.079 0.920 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.080 0.920 0.000
E61 Deficiency of other nutrient elements
0.076 0.922 0.001
E73 Lactose intolerance
0.074 0.926 0.000
E87.2 Acidosis
0.074 0.926 0.000
E28.2 Polycystic ovarian syndrome
0.073 0.927 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.073 0.927 0.000
E78.1 Pure hyperglyceridaemia
0.071 0.929 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.069 0.930 0.001
E79 Disorders of purine and pyrimidine metabolism
0.070 0.930 0.000
E74 Other disorders of carbohydrate metabolism
0.069 0.931 0.000
E67.8 Other specified hyperalimentation
0.069 0.931 0.000
E67.3 Hypervitaminosis D
0.069 0.931 0.000
E67.2 Megavitamin-B6 syndrome
0.069 0.931 0.000
E67.1 Hypercarotenaemia
0.069 0.931 0.000
E67.0 Hypervitaminosis A
0.069 0.931 0.000
E84 Cystic fibrosis
0.068 0.932 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.067 0.933 0.000
E53.9 Vitamin B deficiency, unspecified
0.066 0.933 0.000
E77 Disorders of glycoprotein metabolism
0.066 0.934 0.000
E76 Disorders of glycosaminoglycan metabolism
0.066 0.934 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.066 0.934 0.000
E72 Other disorders of amino-acid metabolism
0.066 0.934 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.066 0.934 0.000
E70 Disorders of aromatic amino-acid metabolism
0.066 0.934 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.066 0.934 0.000
E78.4 Other hyperlipidaemia
0.066 0.934 0.000
E87.0 Hyperosmolality and hypernatraemia
0.064 0.936 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.062 0.936 0.002
E21.4 Other specified disorders of parathyroid gland
0.062 0.936 0.002
E21.2 Other hyperparathyroidism
0.062 0.936 0.002
E53.1 Pyridoxine deficiency
0.062 0.937 0.000
E53.0 Riboflavin deficiency
0.062 0.937 0.000
E73.9 Lactose intolerance, unspecified
0.061 0.939 0.000
E78.3 Hyperchylomicronaemia
0.060 0.940 0.000
E78.2 Mixed hyperlipidaemia
0.058 0.942 0.000
E78.6 Lipoprotein deficiency
0.057 0.943 0.000
E61.9 Deficiency of nutrient element, unspecified
0.055 0.944 0.001
E61.8 Deficiency of other specified nutrient elements
0.055 0.944 0.001
E61.7 Deficiency of multiple nutrient elements
0.055 0.944 0.001
E61.6 Vanadium deficiency
0.055 0.944 0.001
E61.5 Molybdenum deficiency
0.055 0.944 0.001
E61.4 Chromium deficiency
0.055 0.944 0.001
E61.3 Manganese deficiency
0.055 0.944 0.001
E61.2 Magnesium deficiency
0.055 0.944 0.001
E61.0 Copper deficiency
0.055 0.944 0.001
E80 Disorders of porphyrin and bilirubin metabolism
0.056 0.944 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.054 0.946 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.053 0.947 0.000
E73.8 Other lactose intolerance
0.053 0.947 0.000
E73.1 Secondary lactase deficiency
0.053 0.947 0.000
E73.0 Congenital lactase deficiency
0.053 0.947 0.000
I61 Intracerebral haemorrhage
0.053 0.947 0.000
E87.4 Mixed disorder of acid-base balance
0.052 0.948 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.052 0.948 0.000
E84.9 Cystic fibrosis, unspecified
0.051 0.949 0.000
G35 Multiple sclerosis
0.050 0.950 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.040 0.950 0.010
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.050 0.950 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.050 0.950 0.000
E79.1 Lesch-Nyhan syndrome
0.050 0.950 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.050 0.950 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.050 0.950 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.050 0.950 0.000
E74.2 Disorders of galactose metabolism
0.050 0.950 0.000
E74.1 Disorders of fructose metabolism
0.050 0.950 0.000
E74.0 Glycogen storage disease
0.050 0.950 0.000
E88 Other metabolic disorders
0.050 0.950 0.000
G90-G99 Other disorders of the nervous system
0.049 0.951 0.000
I61.8 Other intracerebral haemorrhage
0.049 0.951 0.000
E84.8 Cystic fibrosis with other manifestations
0.049 0.951 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.049 0.951 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.049 0.951 0.000
G91 Hydrocephalus
0.049 0.951 0.000
M17.9 Gonarthrosis, unspecified
0.000 0.951 0.049
G93 Other disorders of brain
0.049 0.951 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.047 0.952 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.047 0.952 0.000
E70.3 Albinism
0.047 0.952 0.000
E70.2 Disorders of tyrosine metabolism
0.047 0.952 0.000
E70.1 Other hyperphenylalaninaemias
0.047 0.952 0.000
E70.0 Classical phenylketonuria
0.047 0.952 0.000
E71.3 Disorders of fatty-acid metabolism
0.047 0.952 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.047 0.952 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.047 0.952 0.000
E71.0 Maple-syrup-urine disease
0.047 0.952 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.047 0.952 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.047 0.952 0.000
E72.5 Disorders of glycine metabolism
0.047 0.952 0.000
E72.4 Disorders of ornithine metabolism
0.047 0.952 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.047 0.952 0.000
E72.2 Disorders of urea cycle metabolism
0.047 0.952 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.047 0.952 0.000
E72.0 Disorders of amino-acid transport
0.047 0.952 0.000
E75.6 Lipid storage disorder, unspecified
0.047 0.952 0.000
E75.5 Other lipid storage disorders
0.047 0.952 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.047 0.952 0.000
E75.3 Sphingolipidosis, unspecified
0.047 0.952 0.000
E75.2 Other sphingolipidosis
0.047 0.952 0.000
E75.1 Other gangliosidosis
0.047 0.952 0.000
E75.0 GM2 gangliosidosis
0.047 0.952 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.047 0.952 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.047 0.952 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.047 0.952 0.000
E76.2 Other mucopolysaccharidoses
0.047 0.952 0.000
E76.1 Mucopolysaccharidosis, type II
0.047 0.952 0.000
E76.0 Mucopolysaccharidosis, type I
0.047 0.952 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.047 0.952 0.000
E77.8 Other disorders of glycoprotein metabolism
0.047 0.952 0.000
E77.1 Defects in glycoprotein degradation
0.047 0.952 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.047 0.952 0.000
G90 Disorders of autonomic nervous system
0.047 0.953 0.000
E87.3 Alkalosis
0.046 0.954 0.000
G91.9 Hydrocephalus, unspecified
0.046 0.954 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.046 0.954 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.046 0.954 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.045 0.955 0.000
E80.6 Other disorders of bilirubin metabolism
0.045 0.955 0.000
G93.6 Cerebral oedema
0.045 0.955 0.000
G91.1 Obstructive hydrocephalus
0.044 0.956 0.000
G93.8 Other specified disorders of brain
0.044 0.956 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.043 0.957 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.043 0.957 0.000
E85 Amyloidosis
0.042 0.957 0.000
G95 Other diseases of spinal cord
0.042 0.958 0.000
G93.9 Disorder of brain, unspecified
0.042 0.958 0.000
G93.4 Encephalopathy, unspecified
0.041 0.959 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.041 0.959 0.000
G90.2 Horner's syndrome
0.041 0.959 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.040 0.960 0.000
E80.5 Crigler-Najjar syndrome
0.040 0.960 0.000
E80.3 Defects of catalase and peroxydase
0.040 0.960 0.000
E80.1 Porphyria cutanea tarda
0.040 0.960 0.000
E80.0 Hereditary erythropoietic porphyria
0.040 0.960 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.040 0.960 0.000
G93.5 Compression of brain
0.040 0.960 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.040 0.960 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.040 0.960 0.000
E80.2 Other porphyria
0.039 0.961 0.000
G93.2 Benign intracranial hypertension
0.038 0.962 0.000
G91.2 Normal-pressure hydrocephalus
0.038 0.962 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.038 0.962 0.000
G95.0 Syringomyelia and syringobulbia
0.037 0.963 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.037 0.963 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.037 0.963 0.000
E05.5 Thyroid crisis or storm
0.029 0.964 0.007
E05.4 Thyrotoxicosis factitia
0.029 0.964 0.007
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.029 0.964 0.007
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.029 0.964 0.007
E88.9 Metabolic disorder, unspecified
0.036 0.964 0.000
E88.8 Other specified metabolic disorders
0.036 0.964 0.000
E88.3 Tumour lysis syndrome
0.036 0.964 0.000
G92 Toxic encephalopathy
0.036 0.964 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.035 0.965 0.000
E89.3 Postprocedural hypopituitarism
0.035 0.965 0.000
G93.7 Reye's syndrome
0.035 0.965 0.000
E05.8 Other thyrotoxicosis
0.027 0.965 0.008
G90.8 Other disorders of autonomic nervous system
0.034 0.966 0.000
G90.4 Autonomic dysreflexia
0.034 0.966 0.000
G90.1 Familial dysautonomia [Riley-Day]
0.034 0.966 0.000
G91.0 Communicating hydrocephalus
0.034 0.966 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.034 0.966 0.000
G95.2 Cord compression, unspecified
0.034 0.966 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.033 0.967 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.033 0.967 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.032 0.968 0.000
G91.8 Other hydrocephalus
0.032 0.968 0.000
E86 Volume depletion
0.032 0.968 0.000
E85.8 Other amyloidosis
0.030 0.969 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.030 0.969 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.030 0.969 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.030 0.969 0.000
E88.2 Lipomatosis, not elsewhere classified
0.030 0.969 0.000
E66 Obesity
0.030 0.970 0.000
G95.9 Disease of spinal cord, unspecified
0.030 0.970 0.000
G95.1 Vascular myelopathies
0.029 0.971 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.029 0.971 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.029 0.971 0.000
E89.5 Postprocedural testicular hypofunction
0.029 0.971 0.000
E89.4 Postprocedural ovarian failure
0.029 0.971 0.000
E89.1 Postprocedural hypoinsulinaemia
0.029 0.971 0.000
E21.3 Hyperparathyroidism, unspecified
0.027 0.971 0.002
G36 Other acute disseminated demyelination
0.029 0.971 0.000
G37 Other demyelinating diseases of central nervous system
0.029 0.971 0.000
G90.3 Multisystem degeneration
0.028 0.972 0.000
E85.3 Secondary systemic amyloidosis
0.027 0.972 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.028 0.972 0.000
G94.1 Hydrocephalus in neoplastic disease
0.027 0.973 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.018 0.973 0.009
G94.2 Hydrocephalus in other diseases classified elsewhere
0.027 0.973 0.000
G93.0 Cerebral cysts
0.027 0.973 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.026 0.973 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.026 0.973 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.026 0.973 0.000
G95.8 Other specified diseases of spinal cord
0.026 0.974 0.000
G96 Other disorders of central nervous system
0.026 0.974 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.026 0.974 0.000
E85.4 Organ-limited amyloidosis
0.026 0.974 0.000
E53.8 Deficiency of other specified B group vitamins
0.026 0.974 0.000
E87.7 Fluid overload
0.026 0.974 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.025 0.974 0.000
Chapter VI Diseases of the nervous system
0.025 0.975 0.000
G97.8 Other postprocedural disorders of nervous system
0.025 0.975 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.024 0.975 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.024 0.975 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.023 0.976 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.023 0.976 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.023 0.977 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.022 0.978 0.000
G36.0 Neuromyelitis optica [Devic]
0.022 0.978 0.000
E85.9 Amyloidosis, unspecified
0.022 0.978 0.001
E66.1 Drug-induced obesity
0.022 0.978 0.000
E80.4 Gilbert's syndrome
0.022 0.978 0.000
E66.0 Obesity due to excess calories
0.022 0.978 0.000
G59.0 Diabetic mononeuropathy
0.022 0.978 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.016 0.978 0.006
J33.0 Polyp of nasal cavity
0.021 0.979 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.021 0.979 0.000
G36.9 Acute disseminated demyelination, unspecified
0.021 0.979 0.000
G36.8 Other specified acute disseminated demyelination
0.021 0.979 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.021 0.979 0.000
G37.5 Concentric sclerosis [Balo]
0.021 0.979 0.000
G37.4 Subacute necrotising myelitis
0.021 0.979 0.000
G37.2 Central pontine myelinolysis
0.021 0.979 0.000
G37.1 Central demyelination of corpus callosum
0.021 0.979 0.000
G37.0 Diffuse sclerosis
0.021 0.979 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.021 0.979 0.000
G96.8 Other specified disorders of central nervous system
0.021 0.979 0.000
H54.0 Blindness, both eyes
0.020 0.980 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.020 0.980 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.020 0.980 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.020 0.980 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.019 0.980 0.000
G96.9 Disorder of central nervous system, unspecified
0.019 0.981 0.000
E61.1 Iron deficiency
0.017 0.981 0.002
J33.8 Other polyp of sinus
0.019 0.981 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.019 0.981 0.000
G93.3 Postviral fatigue syndrome
0.018 0.982 0.000
G82 Paraplegia and tetraplegia
0.018 0.982 0.000
J33 Nasal polyp
0.018 0.982 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.018 0.982 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.018 0.982 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.017 0.983 0.000
G52 Disorders of other cranial nerves
0.017 0.983 0.000
G83 Other paralytic syndromes
0.017 0.983 0.000
G82.2 Paraplegia, unspecified
0.016 0.984 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.016 0.984 0.000
E89.2 Postprocedural hypoparathyroidism
0.016 0.984 0.000
E87.5 Hyperkalaemia
0.016 0.984 0.000
M17 Gonarthrosis [arthrosis of knee]
0.000 0.985 0.015

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.