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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2284169
log Bayes Factor = 39.125
Chromosome 6   position 30,172,385  (GRCh37) Explore rs2284169 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.007 0.993
E00-E07 Disorders of thyroid gland
0.000 0.012 0.988
M50 Cervical disk disorders
0.986 0.014 0.000
M05-M14 Inflammatory polyarthropathies
0.972 0.017 0.010
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.982 0.018 0.000
M50-M54 Other dorsopathies
0.982 0.018 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.020 0.980
M50.1 Cervical disk disorder with radiculopathy
0.980 0.020 0.000
M86-M90 Other osteopathies
0.979 0.021 0.000
M07 Psoriatic and enteropathic arthropathies
0.969 0.027 0.005
M50.3 Other cervical disk degeneration
0.970 0.030 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.032 0.968
M07.3 Other psoriatic arthropathies
0.967 0.033 0.001
M89 Other disorders of bone
0.965 0.035 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.041 0.959
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.041 0.959
M89.9 Disorder of bone, unspecified
0.957 0.043 0.000
E06 Thyroiditis
0.000 0.045 0.955
M07.30 Other psoriatic arthropathies (Multiple sites)
0.944 0.056 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.058 0.942
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.941 0.059 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.933 0.067 0.000
M06 Other rheumatoid arthritis
0.031 0.067 0.902
E05.9 Thyrotoxicosis, unspecified
0.000 0.067 0.933
E06.3 Autoimmune thyroiditis
0.000 0.070 0.930
M45-M49 Spondylopathies
0.928 0.072 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.082 0.918
M47 Spondylosis
0.913 0.087 0.000
M47.8 Other spondylosis
0.904 0.096 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.901 0.099 0.000
M60-M63 Disorders of muscles
0.895 0.105 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.124 0.876
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.125 0.875
E10 Insulin-dependent diabetes mellitus
0.000 0.127 0.873
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.127 0.873
M87 Osteonecrosis
0.871 0.129 0.000
M50.0 Cervical disk disorder with myelopathy
0.870 0.130 0.000
E10-E14 Diabetes mellitus
0.000 0.133 0.867
E10.9 Without complications
0.000 0.134 0.866
M89.94 Disorder of bone, unspecified (Hand)
0.850 0.150 0.000
M06.0 Seronegative rheumatoid arthritis
0.012 0.157 0.831
L40.8 Other psoriasis
0.842 0.158 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.163 0.837
E03.8 Other specified hypothyroidism
0.000 0.174 0.826
M62 Other disorders of muscle
0.822 0.178 0.000
M11 Other crystal arthropathies
0.812 0.183 0.006
M91-M94 Chondropathies
0.817 0.183 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.185 0.815
M90 Osteopathies in diseases classified elsewhere
0.811 0.189 0.000
L40.0 Psoriasis vulgaris
0.802 0.198 0.000
L40.1 Generalised pustular psoriasis
0.802 0.198 0.000
M50.8 Other cervical disk disorders
0.801 0.199 0.000
E10.1 With ketoacidosis
0.000 0.202 0.798
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.790 0.209 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.003 0.210 0.788
M10 Gout
0.786 0.210 0.004
M06.4 Inflammatory polyarthropathy
0.015 0.211 0.774
M53 Other dorsopathies, not elsewhere classified
0.787 0.213 0.000
M88 Paget's disease of bone [osteitis deformans]
0.774 0.226 0.000
M13 Other arthritis
0.771 0.226 0.003
M46 Other inflammatory spondylopathies
0.764 0.236 0.000
M94 Other disorders of cartilage
0.754 0.246 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.752 0.247 0.000
M70-M79 Other soft tissue disorders
0.747 0.253 0.000
M89.3 Hypertrophy of bone
0.744 0.256 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.744 0.256 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.738 0.262 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.734 0.265 0.001
M47.2 Other spondylosis with radiculopathy
0.732 0.268 0.000
E10.4 With neurological complications
0.000 0.268 0.732
M87.2 Osteonecrosis due to previous trauma
0.731 0.269 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.271 0.729
M00-M03 Infectious arthropathies
0.728 0.272 0.000
M47.89 Other spondylosis (Site unspecified)
0.725 0.275 0.000
E10.0 With coma
0.000 0.276 0.724
M87.9 Osteonecrosis, unspecified
0.721 0.279 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
M50.2 Other cervical disk displacement
0.714 0.286 0.000
E10.5 With peripheral circulatory complications
0.000 0.287 0.713
E03.5 Myxoedema coma
0.000 0.288 0.712
E03.4 Atrophy of thyroid (acquired)
0.000 0.288 0.712
E03.3 Postinfectious hypothyroidism
0.000 0.288 0.712
E03.1 Congenital hypothyroidism without goitre
0.000 0.288 0.712
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.288 0.712
M47.1 Other spondylosis with myelopathy
0.710 0.290 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.291 0.708
E00 Congenital iodine-deficiency syndrome
0.000 0.291 0.708
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.291 0.708
M47.85 Other spondylosis (Thoracolumbar region)
0.705 0.295 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.697 0.295 0.007
M08 Juvenile arthritis
0.697 0.295 0.007
M12 Other specific arthropathies
0.693 0.300 0.007
M77 Other enthesopathies
0.699 0.301 0.000
M07.6 Other enteropathic arthropathies
0.695 0.302 0.003
M07.5 Arthropathy in ulcerative colitis
0.695 0.302 0.003
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.695 0.302 0.003
M07.2 Psoriatic spondylitis
0.695 0.302 0.003
M07.1 Arthritis mutilans
0.695 0.302 0.003
M07.0 Distal interphalangeal psoriatic arthropathy
0.695 0.302 0.003
E05.5 Thyroid crisis or storm
0.000 0.306 0.694
E05.4 Thyrotoxicosis factitia
0.000 0.306 0.694
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.306 0.694
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.306 0.694
M07.38 Other psoriatic arthropathies (Other)
0.693 0.306 0.001
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.693 0.306 0.001
M07.33 Other psoriatic arthropathies (Forearm)
0.693 0.306 0.001
M07.32 Other psoriatic arthropathies (Upper arm)
0.693 0.306 0.001
M07.31 Other psoriatic arthropathies (Shoulder region)
0.693 0.306 0.001
M49 Spondylopathies in diseases classified elsewhere
0.692 0.308 0.000
M89.6 Osteopathy after poliomyelitis
0.692 0.308 0.000
M89.2 Other disorders of bone development and growth
0.692 0.308 0.000
M89.1 Epiphyseal arrest
0.692 0.308 0.000
M62.8 Other specified disorders of muscle
0.691 0.309 0.000
E06.9 Thyroiditis, unspecified
0.000 0.310 0.690
M94.8 Other specified disorders of cartilage
0.690 0.310 0.000
E50-E64 Other nutritional deficiencies
0.000 0.311 0.689
M62.4 Contracture of muscle
0.688 0.312 0.000
M46.4 Discitis, unspecified
0.688 0.312 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.313 0.687
M89.99 Disorder of bone, unspecified (Site unspecified)
0.686 0.314 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.686 0.314 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.686 0.314 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.686 0.314 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.686 0.314 0.000
E06.5 Other chronic thyroiditis
0.000 0.315 0.684
E06.4 Drug-induced thyroiditis
0.000 0.315 0.684
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.315 0.684
E06.1 Subacute thyroiditis
0.000 0.315 0.684
E06.0 Acute thyroiditis
0.000 0.315 0.684
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.320 0.680
M60 Myositis
0.679 0.321 0.000
M06.3 Rheumatoid nodule
0.022 0.322 0.656
M47.84 Other spondylosis (Thoracic region)
0.677 0.322 0.000
E27 Other disorders of adrenal gland
0.000 0.324 0.676
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.673 0.327 0.000
M11.2 Other chondrocalcinosis
0.670 0.328 0.003
M06.8 Other specified rheumatoid arthritis
0.022 0.331 0.647
M06.2 Rheumatoid bursitis
0.022 0.331 0.647
M06.1 Adult-onset Still's disease
0.022 0.331 0.647
M86 Osteomyelitis
0.664 0.336 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.663 0.337 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.659 0.340 0.001
M50.9 Cervical disk disorder, unspecified
0.659 0.341 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.007 0.345 0.648
E10.2 With renal complications
0.000 0.345 0.655
M47.0 Anterior spinal and vertebral artery compression syndromes
0.654 0.345 0.000
M89.0 Algoneurodystrophy
0.652 0.348 0.000
M87.8 Other osteonecrosis
0.650 0.350 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.351 0.649
M47.83 Other spondylosis (Cervicothoracic region)
0.648 0.352 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.648 0.352 0.000
M10.0 Idiopathic gout
0.644 0.354 0.003
M87.97 Osteonecrosis, unspecified (Ankle and foot)
0.645 0.355 0.000
M89.5 Osteolysis
0.644 0.355 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.642 0.358 0.000
M61 Calcification and ossification of muscle
0.642 0.358 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.641 0.359 0.000
E05.8 Other thyrotoxicosis
0.000 0.361 0.639
M89.8 Other specified disorders of bone
0.634 0.366 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.632 0.368 0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.630 0.370 0.000
M11.8 Other specified crystal arthropathies
0.625 0.371 0.004
M88.9 Paget's disease of bone, unspecified
0.628 0.372 0.000
M65-M68 Disorders of synovium and tendon
0.627 0.373 0.000
M90.7 Fracture of bone in neoplastic disease
0.626 0.373 0.000
M94.86 Other specified disorders of cartilage (Lower leg)
0.626 0.374 0.000
E10.7 With multiple complications
0.000 0.374 0.626
E10.6 With other specified complications
0.000 0.374 0.626
M87.3 Other secondary osteonecrosis
0.625 0.375 0.000
M87.1 Osteonecrosis due to drugs
0.625 0.375 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.625 0.375 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.624 0.375 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.378 0.622
M62.0 Diastasis of muscle
0.622 0.378 0.000
M94.9 Disorder of cartilage, unspecified
0.622 0.378 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.009 0.378 0.613
M46.46 Discitis, unspecified (Lumbar region)
0.619 0.381 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.617 0.383 0.000
E13 Other specified diabetes mellitus
0.000 0.384 0.616
M89.98 Disorder of bone, unspecified (Other)
0.615 0.385 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.611 0.389 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.390 0.610
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.392 0.608
E40-E46 Malnutrition
0.000 0.392 0.608
E10.8 With unspecified complications
0.000 0.395 0.605
M40-M43 Deforming dorsopathies
0.605 0.395 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.009 0.396 0.596
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.009 0.396 0.596
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.009 0.396 0.596
M06.04 Seronegative rheumatoid arthritis (Hand)
0.009 0.396 0.596
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.009 0.396 0.596
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.009 0.396 0.596
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.009 0.396 0.596
M89.96 Disorder of bone, unspecified (Lower leg)
0.601 0.399 0.000
M77.4 Metatarsalgia
0.600 0.400 0.000
M13.0 Polyarthritis, unspecified
0.597 0.402 0.002
M14 Arthropathies in other diseases classified elsewhere
0.590 0.402 0.008
M53.8 Other specified dorsopathies
0.596 0.404 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.596 0.404 0.000
M13.9 Arthritis, unspecified
0.594 0.406 0.000
M62.46 Contracture of muscle (Lower leg)
0.592 0.407 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.007 0.409 0.585
M62.9 Disorder of muscle, unspecified
0.590 0.410 0.000
M62.6 Muscle strain
0.590 0.410 0.000
M62.3 Immobility syndrome (paraplegic)
0.590 0.410 0.000
M62.2 Ischaemic infarction of muscle
0.590 0.410 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.412 0.588
M77.0 Medial epicondylitis
0.587 0.413 0.000
M11.9 Crystal arthropathy, unspecified
0.582 0.414 0.004
M11.1 Familial chondrocalcinosis
0.582 0.414 0.004
M11.0 Hydroxyapatite deposition disease
0.582 0.414 0.004
M89.37 Hypertrophy of bone (Ankle and foot)
0.585 0.414 0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)
0.585 0.415 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.416 0.584
M06.34 Rheumatoid nodule (Hand)
0.009 0.417 0.574
M90.6 Osteitis deformans in neoplastic disease
0.582 0.418 0.000
M90.5 Osteonecrosis in other diseases classified elsewhere
0.582 0.418 0.000
M90.4 Osteonecrosis due to heamoglobinopathy
0.582 0.418 0.000
M90.3 Osteonecrosis in caisson disease
0.582 0.418 0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.582 0.418 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.582 0.418 0.000
M90.0 Tuberculosis of bone
0.582 0.418 0.000
M94.0 Chondrocostal junction syndrome [Tietze]
0.581 0.419 0.000
M94.88 Other specified disorders of cartilage (Other)
0.579 0.421 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.578 0.422 0.000
M10.9 Gout, unspecified
0.576 0.423 0.001
M77.1 Lateral epicondylitis
0.577 0.423 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.009 0.425 0.567
E27.8 Other specified disorders of adrenal gland
0.000 0.425 0.575
M62.81 Other specified disorders of muscle (Shoulder region)
0.575 0.425 0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)
0.571 0.429 0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.570 0.430 0.000
E07 Other disorders of thyroid
0.000 0.431 0.569
M11.26 Other chondrocalcinosis (Lower leg)
0.568 0.431 0.001
M13.97 Arthritis, unspecified (Ankle and foot)
0.568 0.432 0.000
M46.2 Osteomyelitis of vertebra
0.567 0.433 0.000
M10.4 Other secondary gout
0.563 0.434 0.003
M10.3 Gout due to impairment of renal function
0.563 0.434 0.003
M10.2 Drug-induced gout
0.563 0.434 0.003
M10.1 Lead-induced gout
0.563 0.434 0.003
M13.8 Other specified arthritis
0.564 0.434 0.002
M06.48 Inflammatory polyarthropathy (Other)
0.011 0.435 0.555
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.011 0.435 0.555
M06.46 Inflammatory polyarthropathy (Lower leg)
0.011 0.435 0.555
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.011 0.435 0.555
M06.44 Inflammatory polyarthropathy (Hand)
0.011 0.435 0.555
M06.43 Inflammatory polyarthropathy (Forearm)
0.011 0.435 0.555
M06.42 Inflammatory polyarthropathy (Upper arm)
0.011 0.435 0.555
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.011 0.435 0.555
M53.9 Dorsopathy, unspecified
0.564 0.435 0.000
M53.2 Spinal instabilities
0.564 0.435 0.000
M53.1 Cervicobrachial syndrome
0.564 0.435 0.000
M53.0 Cervicocranial syndrome
0.564 0.435 0.000
M71 Other bursopathies
0.564 0.436 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.439 0.561
M72 Fibroblastic disorders
0.557 0.443 0.000
M90.80 Osteopathy in other diseases classified elsewhere (Multiple sites)
0.556 0.444 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.555 0.445 0.000
M88.8 Paget's disease of other bones
0.555 0.445 0.000
M88.0 Paget's disease of skull
0.555 0.445 0.000
E10.3 With ophthalmic complications
0.000 0.445 0.555
E55 Vitamin D deficiency
0.000 0.445 0.555
M00 Pyogenic arthritis
0.550 0.450 0.000
M46.8 Other specified inflammatory spondylopathies
0.548 0.452 0.000
M46.5 Other infective spondylopathies
0.548 0.452 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.548 0.452 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.548 0.452 0.000
M46.0 Spinal enthesopathy
0.548 0.452 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.547 0.453 0.000
M10.09 Idiopathic gout (Site unspecified)
0.542 0.456 0.001
M62.88 Other specified disorders of muscle (Other)
0.542 0.458 0.000
M87.98 Osteonecrosis, unspecified (Other)
0.541 0.459 0.000
M94.3 Chondrolysis
0.541 0.459 0.000
M94.1 Relapsing polychondritis
0.541 0.459 0.000
M13.1 Monoarthritis, not elsewhere classified
0.537 0.461 0.002
M46.44 Discitis, unspecified (Thoracic region)
0.536 0.464 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.536 0.464 0.000
E34 Other endocrine disorders
0.000 0.465 0.535
M05 Seropositive rheumatoid arthritis
0.523 0.465 0.012
M13.94 Arthritis, unspecified (Hand)
0.535 0.465 0.000
M89.39 Hypertrophy of bone (Site unspecified)
0.533 0.466 0.000
M89.38 Hypertrophy of bone (Other)
0.533 0.466 0.000
M89.36 Hypertrophy of bone (Lower leg)
0.533 0.466 0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)
0.533 0.466 0.000
M89.34 Hypertrophy of bone (Hand)
0.533 0.466 0.000
M89.33 Hypertrophy of bone (Forearm)
0.533 0.466 0.000
M89.32 Hypertrophy of bone (Upper arm)
0.533 0.466 0.000
M89.31 Hypertrophy of bone (Shoulder region)
0.533 0.466 0.000
M89.30 Hypertrophy of bone (Multiple sites)
0.533 0.466 0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)
0.533 0.467 0.000
M89.48 Other hypertrophic osteoarthropathy (Other)
0.533 0.467 0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)
0.533 0.467 0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)
0.533 0.467 0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)
0.533 0.467 0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)
0.533 0.467 0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)
0.533 0.467 0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)
0.533 0.467 0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)
0.533 0.467 0.000
M77.9 Enthesopathy, unspecified
0.532 0.468 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.531 0.469 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.530 0.470 0.000
M77.47 Metatarsalgia-Ankle/Foot
0.529 0.471 0.000
M13.98 Arthritis, unspecified (Other)
0.529 0.471 0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)
0.527 0.473 0.000
M60.0 Infective myositis
0.527 0.473 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.473 0.526
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.525 0.475 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.525 0.475 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.525 0.475 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.525 0.475 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.525 0.475 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.525 0.475 0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.525 0.475 0.000
M93 Other osteochondropathies
0.525 0.475 0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)
0.524 0.476 0.000
M87.28 Osteonecrosis due to previous trauma (Other)
0.524 0.476 0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)
0.524 0.476 0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)
0.524 0.476 0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)
0.524 0.476 0.000
M87.24 Osteonecrosis due to previous trauma (Hand)
0.524 0.476 0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)
0.524 0.476 0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)
0.524 0.476 0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)
0.524 0.476 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.523 0.477 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.522 0.478 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.522 0.478 0.000
M62.84 Other specified disorders of muscle (Hand)
0.518 0.481 0.000
M02 Reactive arthropathies
0.518 0.482 0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)
0.517 0.483 0.000
M87.94 Osteonecrosis, unspecified (Hand)
0.517 0.483 0.000
M87.93 Osteonecrosis, unspecified (Forearm)
0.517 0.483 0.000
M87.92 Osteonecrosis, unspecified (Upper arm)
0.517 0.483 0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)
0.517 0.483 0.000
M99 Biomechanical lesions, not elsewhere classified
0.516 0.483 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.516 0.484 0.000
E29 Testicular dysfunction
0.000 0.487 0.512
M47.19 Other spondylosis with myelopathy (Site unspecified)
0.509 0.491 0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)
0.509 0.491 0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)
0.509 0.491 0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)
0.509 0.491 0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)
0.509 0.491 0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)
0.509 0.491 0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)
0.509 0.491 0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)
0.509 0.491 0.000
E20 Hypoparathyroidism
0.000 0.491 0.509
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.492 0.508
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.492 0.508
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.492 0.508
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.492 0.508
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.492 0.508
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.492 0.508
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.492 0.508
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.492 0.508
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)
0.507 0.493 0.000
M51 Other intervertebral disk disorders
0.507 0.493 0.000
M77.02 Medial epicondylitis (Upper arm)
0.506 0.494 0.000
M08.9 Juvenile arthritis, unspecified
0.500 0.495 0.005
M08.8 Other juvenile arthritis
0.500 0.495 0.005
M08.4 Pauciarticular juvenile arthritis
0.500 0.495 0.005
M08.3 Juvenile polyarthritis (seronegative)
0.500 0.495 0.005
M08.2 Juvenile arthritis with systemic onset
0.500 0.495 0.005
M08.1 Juvenile ankylosing spondylitis
0.500 0.495 0.005
M08.0 Juvenile rheumatoid arthritis
0.500 0.495 0.005
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.500 0.495 0.005
M09.2 Juvenile arthritis in ulcerative colitis
0.500 0.495 0.005
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.500 0.495 0.005
M09.0 Juvenile arthritis in psoriasis
0.500 0.495 0.005
M90.71 Fracture of bone in neoplastic disease (Shoulder region)
0.502 0.498 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.497 0.498 0.005
M12.5 Traumatic arthropathy
0.497 0.498 0.005
M12.4 Intermittent hydrarthrosis
0.497 0.498 0.005
M12.3 Palindromic rheumatism
0.497 0.498 0.005
M12.1 Kaschin-Beck disease
0.497 0.498 0.005
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.497 0.498 0.005
M76 Enthesopathies of lower limb, excluding foot
0.502 0.498 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.501 0.499 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.501 0.499 0.000
M77.3 Calcaneal spur
0.501 0.499 0.000
M77.2 Periarthritis of wrist
0.501 0.499 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.498 0.499 0.003
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.498 0.499 0.003
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.498 0.499 0.003
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.498 0.499 0.003
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.498 0.499 0.003
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.498 0.499 0.003
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.498 0.499 0.003
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.498 0.499 0.003
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.498 0.499 0.003
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.498 0.499 0.003
M07.19 Arthritis mutilans (Site unspecified)
0.498 0.499 0.003
M07.18 Arthritis mutilans (Other)
0.498 0.499 0.003
M07.17 Arthritis mutilans (Ankle and foot)
0.498 0.499 0.003
M07.16 Arthritis mutilans (Lower leg)
0.498 0.499 0.003
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.498 0.499 0.003
M07.14 Arthritis mutilans (Hand)
0.498 0.499 0.003
M07.13 Arthritis mutilans (Forearm)
0.498 0.499 0.003
M07.12 Arthritis mutilans (Upper arm)
0.498 0.499 0.003
M07.11 Arthritis mutilans (Shoulder region)
0.498 0.499 0.003
M07.10 Arthritis mutilans (Multiple sites)
0.498 0.499 0.003
M07.29 Psoriatic spondylitis (Site unspecified)
0.498 0.499 0.003
M07.28 Psoriatic spondylitis (Other)
0.498 0.499 0.003
M07.27 Psoriatic spondylitis (Ankle and foot)
0.498 0.499 0.003
M07.26 Psoriatic spondylitis (Lower leg)
0.498 0.499 0.003
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.498 0.499 0.003
M07.24 Psoriatic spondylitis (Hand)
0.498 0.499 0.003
M07.23 Psoriatic spondylitis (Forearm)
0.498 0.499 0.003
M07.22 Psoriatic spondylitis (Upper arm)
0.498 0.499 0.003
M07.21 Psoriatic spondylitis (Shoulder region)
0.498 0.499 0.003
M07.20 Psoriatic spondylitis (Multiple sites)
0.498 0.499 0.003
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.498 0.499 0.003
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.498 0.499 0.003
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.498 0.499 0.003
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.498 0.499 0.003
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.498 0.499 0.003
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.498 0.499 0.003
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.498 0.499 0.003
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.498 0.499 0.003
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.498 0.499 0.003
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.498 0.499 0.003
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.498 0.499 0.003
M07.58 Arthropathy in ulcerative colitis (Other)
0.498 0.499 0.003
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.498 0.499 0.003
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.498 0.499 0.003
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.498 0.499 0.003
M07.54 Arthropathy in ulcerative colitis (Hand)
0.498 0.499 0.003
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.498 0.499 0.003
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.498 0.499 0.003
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.498 0.499 0.003
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.498 0.499 0.003
M07.69 Other enteropathic arthropathies (Site unspecified)
0.498 0.499 0.003
M07.68 Other enteropathic arthropathies (Other)
0.498 0.499 0.003
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.498 0.499 0.003
M07.66 Other enteropathic arthropathies (Lower leg)
0.498 0.499 0.003
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.498 0.499 0.003
M07.64 Other enteropathic arthropathies (Hand)
0.498 0.499 0.003
M07.63 Other enteropathic arthropathies (Forearm)
0.498 0.499 0.003
M07.62 Other enteropathic arthropathies (Upper arm)
0.498 0.499 0.003
M07.61 Other enteropathic arthropathies (Shoulder region)
0.498 0.499 0.003
M07.60 Other enteropathic arthropathies (Multiple sites)
0.498 0.499 0.003
M66 Spontaneous rupture of synovium and tendon
0.500 0.500 0.000
M12.2 Villonodular synovitis (pigmented)
0.492 0.503 0.005
M49.8 Spondylopathy in other diseases classified elsewhere
0.496 0.504 0.000
M49.4 Neuropathic spondylopathy
0.496 0.504 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.496 0.504 0.000
M49.2 Enterobacterial spondylitis
0.496 0.504 0.000
M49.1 Brucella spondylitis
0.496 0.504 0.000
M49.0 Tuberculosis of spine
0.496 0.504 0.000
M89.19 Epiphyseal arrest (Site unspecified)
0.496 0.504 0.000
M89.18 Epiphyseal arrest (Other)
0.496 0.504 0.000
M89.17 Epiphyseal arrest (Ankle and foot)
0.496 0.504 0.000
M89.16 Epiphyseal arrest (Lower leg)
0.496 0.504 0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)
0.496 0.504 0.000
M89.14 Epiphyseal arrest (Hand)
0.496 0.504 0.000
M89.13 Epiphyseal arrest (Forearm)
0.496 0.504 0.000
M89.12 Epiphyseal arrest (Upper arm)
0.496 0.504 0.000
M89.11 Epiphyseal arrest (Shoulder region)
0.496 0.504 0.000
M89.10 Epiphyseal arrest (Multiple sites)
0.496 0.504 0.000
M89.29 Other disorders of bone development and growth (Site unspecified)
0.496 0.504 0.000
M89.28 Other disorders of bone development and growth (Other)
0.496 0.504 0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)
0.496 0.504 0.000
M89.26 Other disorders of bone development and growth (Lower leg)
0.496 0.504 0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)
0.496 0.504 0.000
M89.24 Other disorders of bone development and growth (Hand)
0.496 0.504 0.000
M89.23 Other disorders of bone development and growth (Forearm)
0.496 0.504 0.000
M89.22 Other disorders of bone development and growth (Upper arm)
0.496 0.504 0.000
M89.21 Other disorders of bone development and growth (Shoulder region)
0.496 0.504 0.000
M89.20 Other disorders of bone development and growth (Multiple sites)
0.496 0.504 0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)
0.496 0.504 0.000
M89.68 Osteopathy after poliomyelitis (Other)
0.496 0.504 0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)
0.496 0.504 0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)
0.496 0.504 0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)
0.496 0.504 0.000
M89.64 Osteopathy after poliomyelitis (Hand)
0.496 0.504 0.000
M89.63 Osteopathy after poliomyelitis (Forearm)
0.496 0.504 0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)
0.496 0.504 0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)
0.496 0.504 0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)
0.496 0.504 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.495 0.505 0.000
E53 Deficiency of other B group vitamins
0.000 0.505 0.495
M94.87 Other specified disorders of cartilage (Ankle and foot)
0.494 0.505 0.000
M94.84 Other specified disorders of cartilage (Hand)
0.494 0.505 0.000
M94.83 Other specified disorders of cartilage (Forearm)
0.494 0.505 0.000
M94.82 Other specified disorders of cartilage (Upper arm)
0.494 0.505 0.000
M94.81 Other specified disorders of cartilage (Shoulder region)
0.494 0.505 0.000
M94.80 Other specified disorders of cartilage (Multiple sites)
0.494 0.505 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.506 0.494
E63 Other nutritional deficiencies
0.000 0.506 0.494
E56 Other vitamin deficiencies
0.000 0.506 0.494
E51 Thiamine deficiency
0.000 0.506 0.494
E50 Vitamin A deficiency
0.000 0.506 0.494
E60 Dietary zinc deficiency
0.000 0.506 0.494
E59 Dietary selenium deficiency
0.000 0.506 0.494
E58 Dietary calcium deficiency
0.000 0.506 0.494

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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