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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2285802
log Bayes Factor = 57.9704
Chromosome 6   position 30,209,099  (GRCh37) Explore rs2285802 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.005 0.995
M06.9 Rheumatoid arthritis, unspecified
0.000 0.006 0.994
E14 Unspecified diabetes mellitus
0.000 0.007 0.993
E03 Other hypothyroidism
0.000 0.007 0.993
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.008 0.992
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.010 0.990
E03.9 Hypothyroidism, unspecified
0.000 0.012 0.988
E14.3 With ophthalmic complications
0.000 0.016 0.984
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.039 0.961
E10.1 With ketoacidosis
0.000 0.043 0.957
E10.3 With ophthalmic complications
0.000 0.051 0.949
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.059 0.941
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.083 0.917
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.083 0.917
E10.0 With coma
0.000 0.105 0.895
E13 Other specified diabetes mellitus
0.000 0.131 0.869
E07 Other disorders of thyroid
0.000 0.138 0.862
E14.8 With unspecified complications
0.000 0.145 0.855
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.149 0.851
E10.4 With neurological complications
0.000 0.159 0.841
E03.8 Other specified hypothyroidism
0.000 0.163 0.837
E14.6 With other specified complications
0.000 0.164 0.836
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.164 0.836
E10.6 With other specified complications
0.000 0.181 0.819
E05.8 Other thyrotoxicosis
0.000 0.193 0.807
E10.7 With multiple complications
0.000 0.219 0.781
E10.5 With peripheral circulatory complications
0.000 0.221 0.779
E07.9 Disorder of thyroid, unspecified
0.000 0.221 0.779
E14.4 With neurological complications
0.000 0.222 0.778
E13.9 Without complications
0.000 0.228 0.772
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.242 0.758
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.248 0.752
M06 Other rheumatoid arthritis
0.000 0.253 0.747
E14.2 Withrenal complications
0.000 0.258 0.742
E10.8 With unspecified complications
0.000 0.261 0.739
E14.1 With ketoacidosis
0.000 0.264 0.736
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.267 0.733
E16 Other disorders of pancreatic internal secretion
0.000 0.279 0.721
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E14.7 With multiple complications
0.000 0.288 0.712
E14.0 With coma
0.000 0.288 0.712
E14.5 With peripheral circulatory complications
0.000 0.288 0.712
E03.5 Myxoedema coma
0.000 0.288 0.712
E03.4 Atrophy of thyroid (acquired)
0.000 0.288 0.712
E03.3 Postinfectious hypothyroidism
0.000 0.288 0.712
E10.2 With renal complications
0.000 0.289 0.711
E03.1 Congenital hypothyroidism without goitre
0.000 0.307 0.693
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.317 0.683
E50-E64 Other nutritional deficiencies
0.000 0.335 0.665
M06.4 Inflammatory polyarthropathy
0.000 0.344 0.656
E13.3 With ophthalmic complications
0.000 0.367 0.633
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.367 0.632
E13.8 With unspecified complications
0.000 0.377 0.623
E13.7 With multiple complications
0.000 0.377 0.623
E13.6 With other specified complications
0.000 0.377 0.623
E13.5 With peripheral circulatory complications
0.000 0.377 0.623
E13.4 With neurological complications
0.000 0.377 0.623
E13.2 With renal complications
0.000 0.377 0.623
E13.1 With ketoacidosis
0.000 0.377 0.623
E13.0 With coma
0.000 0.377 0.623
M06.3 Rheumatoid nodule
0.000 0.377 0.623
E07.1 Dyshormogenetic goitre
0.000 0.382 0.618
E07.0 Hypersecretion of calcitonin
0.000 0.382 0.618
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.388 0.612
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.390 0.610
E16.2 Hypoglycaemia, unspecified
0.000 0.392 0.608
E15 Nondiabetic hypoglycaemic coma
0.000 0.401 0.599
E40-E46 Malnutrition
0.000 0.405 0.595
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.413 0.587
E07.8 Other specified disorders of thyroid
0.000 0.426 0.574
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.441 0.559
M06.0 Seronegative rheumatoid arthritis
0.000 0.447 0.553
M06.2 Rheumatoid bursitis
0.000 0.464 0.536
M06.1 Adult-onset Still's disease
0.000 0.464 0.536
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.483 0.517
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.483 0.517
E16.4 Abnormal secretion of gastrin
0.000 0.483 0.517
E16.3 Increased secretion of glucagon
0.000 0.483 0.517
M06.34 Rheumatoid nodule (Hand)
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
E56 Other vitamin deficiencies
0.000 0.490 0.509
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.501 0.499
M06.8 Other specified rheumatoid arthritis
0.000 0.503 0.497
E16.1 Other hypoglycaemia
0.000 0.503 0.497
E61 Deficiency of other nutrient elements
0.000 0.503 0.496
E20-E35 Disorders of other endocrine glands
0.000 0.510 0.490
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.511 0.489
E54 Ascorbic acid deficiency
0.000 0.513 0.487
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.514 0.486
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.523 0.477
E50 Vitamin A deficiency
0.000 0.523 0.477
E60 Dietary zinc deficiency
0.000 0.523 0.477
E59 Dietary selenium deficiency
0.000 0.523 0.477
E52 Niacin deficiency [pellagra]
0.000 0.523 0.477
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.529 0.471
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.529 0.471
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.529 0.471
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.529 0.471
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.529 0.471
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.529 0.471
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.529 0.471
E55 Vitamin D deficiency
0.000 0.540 0.460
E53 Deficiency of other B group vitamins
0.000 0.541 0.459
E63 Other nutritional deficiencies
0.000 0.541 0.459
E51 Thiamine deficiency
0.000 0.548 0.452
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.553 0.447
M06.38 Rheumatoid nodule (Other)
0.000 0.553 0.447
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.553 0.447
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.553 0.447
M06.33 Rheumatoid nodule (Forearm)
0.000 0.553 0.447
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.553 0.447
E58 Dietary calcium deficiency
0.000 0.559 0.441
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.567 0.433
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.569 0.431
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.573 0.427
E45 Retarded development following protein-energy malnutrition
0.000 0.573 0.427
E43 Unspecified severe protein-energy malnutrition
0.000 0.573 0.427
E42 Marasmic kwashiorkor
0.000 0.573 0.427
E41 Nutritional marasmus
0.000 0.573 0.427
E40 Kwashiorkor
0.000 0.573 0.427
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.580 0.420
E27 Other disorders of adrenal gland
0.000 0.582 0.418
E06 Thyroiditis
0.000 0.595 0.405
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.597 0.403
G35 Multiple sclerosis
0.400 0.600 0.000
E24 Cushing's syndrome
0.000 0.601 0.399
E61.1 Iron deficiency
0.000 0.601 0.399
E56.1 Deficiency of vitamin K
0.000 0.602 0.398
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.603 0.397
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.603 0.397
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.603 0.397
K90 Intestinal malabsorption
0.000 0.604 0.396
E27.1 Primary adrenocortical insufficiency
0.000 0.607 0.393
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.609 0.391
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.616 0.384
M06.18 Adult-onset Still's disease (Other)
0.000 0.616 0.384
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.616 0.384
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.616 0.384
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.616 0.384
M06.14 Adult-onset Still's disease (Hand)
0.000 0.616 0.384
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.616 0.384
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.616 0.384
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.616 0.384
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.616 0.384
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.616 0.384
M06.28 Rheumatoid bursitis (Other)
0.000 0.616 0.384
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.616 0.384
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.616 0.384
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.616 0.384
M06.24 Rheumatoid bursitis (Hand)
0.000 0.616 0.384
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.616 0.384
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.616 0.384
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.616 0.384
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.616 0.384
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.624 0.376
E22 Hyperfunction of pituitary gland
0.000 0.631 0.369
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.632 0.367
E31 Polyglandular dysfunction
0.000 0.633 0.367
E56.9 Vitamin deficiency, unspecified
0.000 0.635 0.365
E56.8 Deficiency of other vitamins
0.000 0.635 0.365
E56.0 Deficiency of vitamin E
0.000 0.635 0.365
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.637 0.363
E20 Hypoparathyroidism
0.000 0.642 0.358
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.643 0.357
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.643 0.357
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.643 0.357
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.643 0.357
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.643 0.357
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.643 0.357
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.643 0.357
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.643 0.357
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.643 0.357
E61.9 Deficiency of nutrient element, unspecified
0.000 0.644 0.356
E61.8 Deficiency of other specified nutrient elements
0.000 0.644 0.356
E61.7 Deficiency of multiple nutrient elements
0.000 0.644 0.356
E61.6 Vanadium deficiency
0.000 0.644 0.356
E61.5 Molybdenum deficiency
0.000 0.644 0.356
E61.4 Chromium deficiency
0.000 0.644 0.356
E61.3 Manganese deficiency
0.000 0.644 0.356
E61.0 Copper deficiency
0.000 0.644 0.356
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.649 0.351
E32 Diseases of thymus
0.000 0.649 0.351
E30 Disorders of puberty, not elsewhere classified
0.000 0.649 0.351
E24.2 Drug-induced Cushing's syndrome
0.000 0.650 0.350
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.652 0.347
E50.9 Vitamin A deficiency, unspecified
0.000 0.658 0.342
E50.8 Other manifestations of vitamin A deficiency
0.000 0.658 0.342
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.658 0.342
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.658 0.342
E50.5 Vitamin A deficiency with night blindness
0.000 0.658 0.342
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.658 0.342
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.658 0.342
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.658 0.342
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.658 0.342
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.658 0.342
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.658 0.342
E64.8 Sequelae of other nutritional deficiencies
0.000 0.658 0.342
E64.3 Sequelae of rickets
0.000 0.658 0.342
E64.2 Sequelae of vitamin C deficiency
0.000 0.658 0.342
E64.1 Sequelae of vitamin A deficiency
0.000 0.658 0.342
E64.0 Sequelae of protein-energy malnutrition
0.000 0.658 0.342
E65-E68 Obesity and other hyperalimentation
0.000 0.658 0.342
E27.9 Disorder of adrenal gland, unspecified
0.000 0.663 0.337
E28 Ovarian dysfunction
0.000 0.663 0.337
E34 Other endocrine disorders
0.000 0.664 0.336
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.664 0.336
E29 Testicular dysfunction
0.000 0.667 0.333
E55.0 Rickets, active
0.000 0.670 0.330
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.670 0.330
E53.1 Pyridoxine deficiency
0.000 0.670 0.329
E53.0 Riboflavin deficiency
0.000 0.670 0.329
E63.8 Other specified nutritional deficiencies
0.000 0.671 0.329
E63.1 Imbalance of constituents of food intake
0.000 0.671 0.329
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.671 0.329
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.672 0.327
E51.9 Thiamine deficiency, unspecified
0.000 0.676 0.324
E51.8 Other manifestations of thiamine deficiency
0.000 0.676 0.324
E51.1 Beriberi
0.000 0.676 0.324
E25 Adrenogenital disorders
0.000 0.676 0.324
E61.2 Magnesium deficiency
0.000 0.677 0.323
E53.8 Deficiency of other specified B group vitamins
0.000 0.678 0.322
K90.8 Other intestinal malabsorption
0.000 0.680 0.320
E53.9 Vitamin B deficiency, unspecified
0.000 0.680 0.320
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.682 0.318
E55.9 Vitamin D deficiency, unspecified
0.000 0.687 0.313
E63.9 Nutritional deficiency, unspecified
0.000 0.689 0.310
E46 Unspecified protein-energy malnutrition
0.000 0.691 0.308
E24.0 Pituitary-dependent Cushing's disease
0.000 0.693 0.307
E44.1 Mild protein-energy malnutrition
0.000 0.694 0.306
E44.0 Moderate protein-energy malnutrition
0.000 0.694 0.306
E27.5 Adrenomedullary hyperfunction
0.000 0.700 0.300
E27.0 Other adrenocortical overactivity
0.000 0.700 0.300
E51.2 Wernicke's encephalopathy
0.000 0.702 0.298
E06.1 Subacute thyroiditis
0.000 0.704 0.296
E06.5 Other chronic thyroiditis
0.000 0.706 0.294
E06.4 Drug-induced thyroiditis
0.000 0.709 0.291
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.709 0.291
E06.0 Acute thyroiditis
0.000 0.709 0.291
E20.9 Hypoparathyroidism, unspecified
0.000 0.712 0.288
E24.8 Other Cushing's syndrome
0.000 0.714 0.286
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.714 0.286
E24.3 Ectopic ACTH syndrome
0.000 0.714 0.286
E24.1 Nelson's syndrome
0.000 0.714 0.286
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.714 0.285
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.716 0.283
K90.3 Pancreatic steatorrhoea
0.000 0.716 0.284
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.716 0.284
K90.1 Tropical sprue
0.000 0.716 0.284
G35-G37 Demyelinating diseases of the central nervous system
0.280 0.720 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.721 0.279
E34.9 Endocrine disorder, unspecified
0.000 0.731 0.269
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.731 0.268
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.735 0.264
E22.8 Other hyperfunction of pituitary gland
0.000 0.735 0.264
E31.9 Polyglandular dysfunction, unspecified
0.000 0.737 0.263
E31.8 Other polyglandular dysfunction
0.000 0.737 0.263
E31.1 Polyglandular hyperfunction
0.000 0.737 0.263
E20.8 Other hypoparathyroidism
0.000 0.743 0.256
E20.0 Idiopathic hypoparathyroidism
0.000 0.743 0.256
E30.9 Disorder of puberty, unspecified
0.000 0.748 0.252
E30.8 Other disorders of puberty
0.000 0.748 0.252
E30.1 Precocious puberty
0.000 0.748 0.252
E30.0 Delayed puberty
0.000 0.748 0.252
E32.9 Disease of thymus, unspecified
0.000 0.748 0.252
E32.8 Other diseases of thymus
0.000 0.748 0.252
E32.1 Abscess of thymus
0.000 0.748 0.252
E32.0 Persistent hyperplasia of thymus
0.000 0.748 0.252
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.748 0.252
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.748 0.252
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.748 0.252
G37 Other demyelinating diseases of central nervous system
0.246 0.754 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.754 0.246
E67 Other hyperalimentation
0.000 0.754 0.245
E68 Sequelae of hyperalimentation
0.000 0.754 0.245
E26 Hyperaldosteronism
0.000 0.757 0.243
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.757 0.242
E28.9 Ovarian dysfunction, unspecified
0.000 0.758 0.241
E28.8 Other ovarian dysfunction
0.000 0.758 0.241
E28.1 Androgen excess
0.000 0.758 0.241
E28.0 Oestrogen excess
0.000 0.758 0.241
E34.5 Androgen resistance syndrome
0.000 0.759 0.241
E34.4 Constitutional tall stature
0.000 0.759 0.241
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.759 0.241
E34.1 Other hypersecretion of intestinal hormones
0.000 0.759 0.241
E22.1 Hyperprolactinaemia
0.000 0.759 0.241
E29.9 Testicular dysfunction, unspecified
0.000 0.761 0.239
E29.8 Other testicular dysfunction
0.000 0.761 0.239
E29.0 Testicular hyperfunction
0.000 0.761 0.239
E28.2 Polycystic ovarian syndrome
0.000 0.761 0.239
E14.9 Without complications
0.000 0.763 0.237
E25.9 Adrenogenital disorder, unspecified
0.000 0.767 0.232
E25.8 Other adrenogenital disorders
0.000 0.767 0.232
E28.3 Primary ovarian failure
0.000 0.771 0.229
G37.9 Demyelinating disease of central nervous system, unspecified
0.228 0.772 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.774 0.226
E34.8 Other specified endocrine disorders
0.000 0.777 0.223
E29.1 Testicular hypofunction
0.000 0.779 0.221
E20.1 Pseudohypoparathyroidism
0.000 0.780 0.220
E23 Hypofunction and other disorders of pituitary gland
0.000 0.781 0.219
G36 Other acute disseminated demyelination
0.216 0.784 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.786 0.214
E83 Disorders of mineral metabolism
0.206 0.793 0.001
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.795 0.205
E27.8 Other specified disorders of adrenal gland
0.000 0.798 0.202
E34.0 Carcinoid syndrome
0.000 0.801 0.199
E21.3 Hyperparathyroidism, unspecified
0.000 0.804 0.196
E27.2 Addisonian crisis
0.000 0.805 0.194
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.187 0.813 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.816 0.184
E23.2 Diabetes insipidus
0.000 0.816 0.184
E06.9 Thyroiditis, unspecified
0.001 0.816 0.183
E83.3 Disorders of phosphorus metabolism
0.181 0.819 0.000
G37.5 Concentric sclerosis [Balo]
0.177 0.823 0.000
G37.4 Subacute necrotising myelitis
0.177 0.823 0.000
G37.2 Central pontine myelinolysis
0.177 0.823 0.000
G37.1 Central demyelination of corpus callosum
0.177 0.823 0.000
G37.0 Diffuse sclerosis
0.177 0.823 0.000
E67.8 Other specified hyperalimentation
0.000 0.824 0.176
E67.3 Hypervitaminosis D
0.000 0.824 0.176
E67.2 Megavitamin-B6 syndrome
0.000 0.824 0.176
E67.1 Hypercarotenaemia
0.000 0.824 0.176
E67.0 Hypervitaminosis A
0.000 0.824 0.176
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.826 0.174
E26.8 Other hyperaldosteronism
0.000 0.826 0.174
E26.1 Secondary hyperaldosteronism
0.000 0.826 0.174
G36.0 Neuromyelitis optica [Devic]
0.170 0.830 0.000
E06.3 Autoimmune thyroiditis
0.000 0.831 0.169
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.837 0.163
E21.2 Other hyperparathyroidism
0.000 0.838 0.162
E83.9 Disorder of mineral metabolism, unspecified
0.158 0.841 0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.843 0.157
E23.1 Drug-induced hypopituitarism
0.000 0.843 0.157
G36.9 Acute disseminated demyelination, unspecified
0.155 0.845 0.000
G36.8 Other specified acute disseminated demyelination
0.155 0.845 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.155 0.845 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.850 0.149
E83.8 Other disorders of mineral metabolism
0.148 0.851 0.001
E83.2 Disorders of zinc metabolism
0.148 0.851 0.001
E83.0 Disorders of copper metabolism
0.148 0.851 0.001
E26.9 Hyperaldosteronism, unspecified
0.001 0.852 0.147
E65 Localised adiposity
0.001 0.855 0.144
G37.8 Other specified demyelinating diseases of central nervous system
0.141 0.858 0.000
E23.6 Other disorders of pituitary gland
0.000 0.883 0.116
E26.0 Primary hyperaldosteronism
0.001 0.885 0.115
E66 Obesity
0.000 0.887 0.113
E23.7 Disorder of pituitary gland, unspecified
0.000 0.890 0.110
M05-M14 Inflammatory polyarthropathies
0.000 0.894 0.106
E04 Other non-toxic goitre
0.000 0.896 0.104
E23.0 Hypopituitarism
0.000 0.900 0.100
E66.8 Other obesity
0.000 0.900 0.100
K75.4 Autoimmune hepatitis
0.000 0.903 0.097
M12 Other specific arthropathies
0.000 0.907 0.093
M05 Seropositive rheumatoid arthritis
0.000 0.911 0.089
O32.1 Maternal care for breech presentation
0.000 0.915 0.085
K75 Other inflammatory liver diseases
0.000 0.915 0.085
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.918 0.082
E66.1 Drug-induced obesity
0.000 0.919 0.081
K72.0 Acute and subacute hepatic failure
0.000 0.919 0.081
K72 Hepatic failure, not elsewhere classified
0.000 0.921 0.079
K70-K77 Diseases of liver
0.000 0.922 0.078
M12.3 Palindromic rheumatism
0.000 0.922 0.078
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.924 0.076
E04.8 Other specified non-toxic goitre
0.000 0.925 0.075
K73 Chronic hepatitis, not elsewhere classified
0.000 0.926 0.074
K74 Fibrosis and cirrhosis of liver
0.000 0.927 0.073
M12.2 Villonodular synovitis (pigmented)
0.000 0.928 0.072
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.928 0.072
M08 Juvenile arthritis
0.000 0.928 0.071
K75.8 Other specified inflammatory liver diseases
0.000 0.929 0.071
M12.5 Traumatic arthropathy
0.000 0.930 0.070
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.930 0.070
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.931 0.069
K73.9 Chronic hepatitis, unspecified
0.000 0.932 0.068
K74.3 Primary biliary cirrhosis
0.000 0.932 0.068
M14 Arthropathies in other diseases classified elsewhere
0.000 0.933 0.067
M12.4 Intermittent hydrarthrosis
0.000 0.933 0.067
M12.1 Kaschin-Beck disease
0.000 0.933 0.067
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.933 0.067
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.933 0.067
M05.8 Other seropositive rheumatoid arthritis
0.000 0.934 0.066
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.934 0.066
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.934 0.066
E04.0 Non-toxic diffuse goitre
0.000 0.935 0.065
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.936 0.064
M05.0 Felty's syndrome
0.000 0.936 0.064
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.936 0.064
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.937 0.063
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.937 0.063
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.939 0.061
K75.2 Nonspecific reactive hepatitis
0.000 0.939 0.061
K75.1 Phlebitis of portal vein
0.000 0.939 0.061
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.000 0.941 0.059
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.941 0.059
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.941 0.059
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.941 0.059
K74.6 Other and unspecified cirrhosis of liver
0.000 0.942 0.058
M11 Other crystal arthropathies
0.000 0.943 0.057
K72.1 Chronic hepatic failure
0.000 0.943 0.057
M05.1 Rheumatoid lung disease
0.000 0.943 0.056
M12.88 Other specific arthropathies, not elsewhere classified (Other)
0.000 0.943 0.056
K77 Liver disorders in diseases classified elsewhere
0.000 0.944 0.056
M12.38 Palindromic rheumatism (Other)
0.000 0.944 0.056
M12.37 Palindromic rheumatism (Ankle and foot)
0.000 0.944 0.056
M12.36 Palindromic rheumatism (Lower leg)
0.000 0.944 0.056
M12.35 Palindromic rheumatism (Pelvic region and thigh)
0.000 0.944 0.056
M12.34 Palindromic rheumatism (Hand)
0.000 0.944 0.056
M12.33 Palindromic rheumatism (Forearm)
0.000 0.944 0.056
M12.32 Palindromic rheumatism (Upper arm)
0.000 0.944 0.056
M12.31 Palindromic rheumatism (Shoulder region)
0.000 0.944 0.056
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.945 0.055
M10 Gout
0.000 0.945 0.055
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.945 0.055
M05.2 Rheumatoid vasculitis
0.000 0.945 0.055
E83.4 Disorders of magnesium metabolism
0.054 0.945 0.001
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.945 0.055
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.945 0.055
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.945 0.055
M09.0 Juvenile arthritis in psoriasis
0.000 0.945 0.055
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.054 0.946 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.946 0.054
K74.1 Hepatic sclerosis
0.000 0.946 0.054
M12.57 Traumatic arthropathy (Ankle and foot)
0.000 0.947 0.053
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.947 0.053
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.947 0.053
T83.1 Mechanical complication of other urinary devices and implants
0.053 0.947 0.000
K74.4 Secondary biliary cirrhosis
0.000 0.947 0.052
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.947 0.052
M12.30 Palindromic rheumatism (Multiple sites)
0.000 0.947 0.052
K74.5 Biliary cirrhosis, unspecified
0.000 0.948 0.052
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.052 0.948 0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)
0.000 0.948 0.052
M12.28 Villonodular synovitis (pigmented) (Other)
0.000 0.948 0.052
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)
0.000 0.948 0.052
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)
0.000 0.948 0.052
M12.23 Villonodular synovitis (pigmented) (Forearm)
0.000 0.948 0.052
M12.22 Villonodular synovitis (pigmented) (Upper arm)
0.000 0.948 0.052
M12.21 Villonodular synovitis (pigmented) (Shoulder region)
0.000 0.948 0.052
M12.20 Villonodular synovitis (pigmented) (Multiple sites)
0.000 0.948 0.052
M12.89 Other specific arthropathies, not elsewhere classified (Site unspecified)
0.000 0.948 0.052
M12.87 Other specific arthropathies, not elsewhere classified (Ankle and foot)
0.000 0.948 0.052
M12.86 Other specific arthropathies, not elsewhere classified (Lower leg)
0.000 0.948 0.052
M12.85 Other specific arthropathies, not elsewhere classified (Pelvic region and thigh)
0.000 0.948 0.052
M12.84 Other specific arthropathies, not elsewhere classified (Hand)
0.000 0.948 0.052
M12.83 Other specific arthropathies, not elsewhere classified (Forearm)
0.000 0.948 0.052
M12.82 Other specific arthropathies, not elsewhere classified (Upper arm)
0.000 0.948 0.052
M12.81 Other specific arthropathies, not elsewhere classified (Shoulder region)
0.000 0.948 0.052
M12.80 Other specific arthropathies, not elsewhere classified (Multiple sites)
0.000 0.948 0.052
M08.9 Juvenile arthritis, unspecified
0.000 0.948 0.051
M08.8 Other juvenile arthritis
0.000 0.948 0.051
M08.4 Pauciarticular juvenile arthritis
0.000 0.948 0.051
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.948 0.051
M08.2 Juvenile arthritis with systemic onset
0.000 0.948 0.051
M08.1 Juvenile ankylosing spondylitis
0.000 0.948 0.051
M12.59 Traumatic arthropathy (Site unspecified)
0.000 0.949 0.050
M12.58 Traumatic arthropathy (Other)
0.000 0.949 0.050
M12.56 Traumatic arthropathy (Lower leg)
0.000 0.949 0.050
M12.55 Traumatic arthropathy (Pelvic region and thigh)
0.000 0.949 0.050
M12.54 Traumatic arthropathy (Hand)
0.000 0.949 0.050
M12.53 Traumatic arthropathy (Forearm)
0.000 0.949 0.050
M12.52 Traumatic arthropathy (Upper arm)
0.000 0.949 0.050
M12.51 Traumatic arthropathy (Shoulder region)
0.000 0.949 0.050
M12.50 Traumatic arthropathy (Multiple sites)
0.000 0.949 0.050
K75.0 Abscess of liver
0.000 0.949 0.050
T83.0 Mechanical complication of urinary (indwelling) catheter
0.050 0.950 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.950 0.050
K72.9 Hepatic failure, unspecified
0.000 0.951 0.049
M14.2 Diabetic arthropathy
0.000 0.951 0.049
K74.0 Hepatic fibrosis
0.000 0.951 0.049
E04.9 Non-toxic goitre, unspecified
0.000 0.951 0.049
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.951 0.048

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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