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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2285803
log Bayes Factor = 64.4626
Chromosome 6   position 31,107,258  (GRCh37) Explore rs2285803 on Ensembl!
Variant rs2285803 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.002 0.998
E78.0 Pure hypercholesterolaemia
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
G35 Multiple sclerosis
0.995 0.005 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.006 0.994
E14 Unspecified diabetes mellitus
0.000 0.008 0.992
E70-E90 Metabolic disorders
0.000 0.009 0.991
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.010 0.990
E16 Other disorders of pancreatic internal secretion
0.000 0.018 0.982
E16.2 Hypoglycaemia, unspecified
0.000 0.026 0.974
E14.9 Without complications
0.000 0.055 0.945
E10.3 With ophthalmic complications
0.000 0.058 0.942
E14.3 With ophthalmic complications
0.000 0.078 0.922
C83.3 Large cell (diffuse)
0.000 0.082 0.918
E11.0 With coma
0.000 0.098 0.902
E83 Disorders of mineral metabolism
0.878 0.114 0.008
E10.1 With ketoacidosis
0.000 0.141 0.859
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.147 0.853
E78.2 Mixed hyperlipidaemia
0.000 0.165 0.835
E11.1 With ketoacidosis
0.000 0.167 0.833
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.169 0.831
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.177 0.823
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.177 0.823
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.181 0.819
E74 Other disorders of carbohydrate metabolism
0.000 0.182 0.818
E40-E46 Malnutrition
0.000 0.183 0.817
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.185 0.815
E10.8 With unspecified complications
0.000 0.202 0.798
E07 Other disorders of thyroid
0.000 0.204 0.796
E10.0 With coma
0.000 0.205 0.795
E10.6 With other specified complications
0.000 0.206 0.794
E83.3 Disorders of phosphorus metabolism
0.791 0.207 0.002
E14.5 With peripheral circulatory complications
0.000 0.209 0.791
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.211 0.789
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.211 0.789
C85.1 B-cell lymphoma, unspecified
0.000 0.212 0.788
E78.4 Other hyperlipidaemia
0.000 0.220 0.780
E13 Other specified diabetes mellitus
0.000 0.225 0.775
E79 Disorders of purine and pyrimidine metabolism
0.000 0.227 0.772
E14.1 With ketoacidosis
0.000 0.232 0.768
E16.1 Other hypoglycaemia
0.000 0.232 0.768
G35-G37 Demyelinating diseases of the central nervous system
0.764 0.236 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.240 0.760
E11.2 With renal complications
0.000 0.240 0.760
E14.4 With neurological complications
0.000 0.242 0.758
E78.8 Other disorders of lipoprotein metabolism
0.000 0.246 0.754
E03.8 Other specified hypothyroidism
0.000 0.246 0.754
E78.1 Pure hyperglyceridaemia
0.000 0.258 0.742
E14.6 With other specified complications
0.000 0.260 0.740
E83.9 Disorder of mineral metabolism, unspecified
0.714 0.281 0.005
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.281 0.719
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
G37 Other demyelinating diseases of central nervous system
0.712 0.288 0.000
E14.7 With multiple complications
0.000 0.289 0.711
E14.0 With coma
0.000 0.289 0.711
E77 Disorders of glycoprotein metabolism
0.000 0.289 0.710
E76 Disorders of glycosaminoglycan metabolism
0.000 0.289 0.710
E72 Other disorders of amino-acid metabolism
0.000 0.289 0.710
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.289 0.710
E70 Disorders of aromatic amino-acid metabolism
0.000 0.289 0.710
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.289 0.710
E15 Nondiabetic hypoglycaemic coma
0.000 0.290 0.709
E78.5 Hyperlipidaemia, unspecified
0.000 0.294 0.706
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.296 0.704
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.296 0.704
E16.4 Abnormal secretion of gastrin
0.000 0.296 0.704
E16.3 Increased secretion of glucagon
0.000 0.296 0.704
E11.8 With unspecified complications
0.000 0.297 0.703
E84 Cystic fibrosis
0.000 0.301 0.699
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.301 0.699
E14.2 Withrenal complications
0.000 0.305 0.695
C82.2 Large cell, follicular
0.000 0.311 0.689
E11.5 With peripheral circulatory complications
0.000 0.313 0.687
E46 Unspecified protein-energy malnutrition
0.000 0.314 0.686
E14.8 With unspecified complications
0.000 0.316 0.684
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.331 0.668
K90 Intestinal malabsorption
0.000 0.332 0.668
G37.9 Demyelinating disease of central nervous system, unspecified
0.666 0.334 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.341 0.659
L40.9 Psoriasis, unspecified
0.000 0.346 0.654
E10.5 With peripheral circulatory complications
0.000 0.346 0.653
C83.7 Burkitt's tumour
0.000 0.354 0.646
E83.4 Disorders of magnesium metabolism
0.639 0.359 0.002
C82.3 Follicular lymphoma grade IIIa
0.000 0.363 0.637
E07.9 Disorder of thyroid, unspecified
0.000 0.363 0.637
E05.8 Other thyrotoxicosis
0.000 0.365 0.635
E03.1 Congenital hypothyroidism without goitre
0.000 0.365 0.635
E83.8 Other disorders of mineral metabolism
0.629 0.365 0.006
E83.2 Disorders of zinc metabolism
0.629 0.365 0.006
E83.0 Disorders of copper metabolism
0.629 0.365 0.006
E88 Other metabolic disorders
0.000 0.368 0.632
E13.9 Without complications
0.000 0.375 0.625
C82.0 Small cleaved cell, follicular
0.000 0.378 0.622
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.384 0.616
E78.3 Hyperchylomicronaemia
0.000 0.385 0.615
C86 Other specified types of T/NK-cell lymphoma
0.000 0.397 0.603
E80.6 Other disorders of bilirubin metabolism
0.000 0.399 0.601
E80.2 Other porphyria
0.000 0.401 0.599
C83.6 Undifferentiated (diffuse)
0.000 0.404 0.596
C83.5 Lymphoblastic (diffuse)
0.000 0.404 0.596
C83.4 Immunoblastic (diffuse)
0.000 0.404 0.596
C83.2 Mixed small and large cell (diffuse)
0.000 0.404 0.596
C82.6 Cutaneous follicle centre lymphoma
0.000 0.410 0.590
C82.5 Diffuse follicle centre lymphoma
0.000 0.410 0.590
E07.8 Other specified disorders of thyroid
0.000 0.411 0.589
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.412 0.587
E10.2 With renal complications
0.000 0.413 0.587
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.413 0.586
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.413 0.586
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.413 0.586
E74.2 Disorders of galactose metabolism
0.000 0.413 0.586
E74.1 Disorders of fructose metabolism
0.000 0.413 0.586
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.414 0.586
E45 Retarded development following protein-energy malnutrition
0.000 0.414 0.586
E43 Unspecified severe protein-energy malnutrition
0.000 0.414 0.586
E42 Marasmic kwashiorkor
0.000 0.414 0.586
E41 Nutritional marasmus
0.000 0.414 0.586
E40 Kwashiorkor
0.000 0.414 0.586
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.416 0.584
C85.0 Lymphosarcoma
0.000 0.416 0.584
E80.4 Gilbert's syndrome
0.000 0.419 0.581
G37.8 Other specified demyelinating diseases of central nervous system
0.577 0.423 0.000
E80.1 Porphyria cutanea tarda
0.000 0.425 0.575
C82.4 Follicular lymphoma grade IIIb
0.000 0.426 0.574
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.427 0.573
E07.1 Dyshormogenetic goitre
0.000 0.429 0.571
E07.0 Hypersecretion of calcitonin
0.000 0.429 0.571
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.431 0.569
G36 Other acute disseminated demyelination
0.568 0.432 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.434 0.566
E80.5 Crigler-Najjar syndrome
0.000 0.434 0.566
E80.3 Defects of catalase and peroxydase
0.000 0.434 0.566
E80.0 Hereditary erythropoietic porphyria
0.000 0.434 0.566
E13.8 With unspecified complications
0.000 0.444 0.556
E13.7 With multiple complications
0.000 0.444 0.556
E13.6 With other specified complications
0.000 0.444 0.556
E13.5 With peripheral circulatory complications
0.000 0.444 0.556
E13.4 With neurological complications
0.000 0.444 0.556
E13.2 With renal complications
0.000 0.444 0.556
E13.1 With ketoacidosis
0.000 0.444 0.556
E13.0 With coma
0.000 0.444 0.556
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.446 0.554
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.446 0.554
E79.1 Lesch-Nyhan syndrome
0.000 0.446 0.554
C94 Other leukaemias of specified cell type
0.000 0.457 0.542
E13.3 With ophthalmic complications
0.000 0.460 0.540
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.463 0.537
K90.9 Intestinal malabsorption, unspecified
0.000 0.466 0.534
E74.0 Glycogen storage disease
0.000 0.468 0.531
C84.0 Mycosis fungoides
0.000 0.472 0.528
E73 Lactose intolerance
0.001 0.476 0.523
E10.4 With neurological complications
0.000 0.482 0.518
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.487 0.513
E83.5 Disorders of calcium metabolism
0.512 0.487 0.001
G37.5 Concentric sclerosis [Balo]
0.510 0.490 0.000
G37.4 Subacute necrotising myelitis
0.510 0.490 0.000
G37.2 Central pontine myelinolysis
0.510 0.490 0.000
G37.1 Central demyelination of corpus callosum
0.510 0.490 0.000
G37.0 Diffuse sclerosis
0.510 0.490 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.490 0.510
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.490 0.509
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.490 0.509
E70.3 Albinism
0.000 0.490 0.509
E70.2 Disorders of tyrosine metabolism
0.000 0.490 0.509
E70.1 Other hyperphenylalaninaemias
0.000 0.490 0.509
E70.0 Classical phenylketonuria
0.000 0.490 0.509
E71.3 Disorders of fatty-acid metabolism
0.000 0.490 0.509
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.490 0.509
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.490 0.509
E71.0 Maple-syrup-urine disease
0.000 0.490 0.509
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.490 0.509
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.490 0.509
E72.5 Disorders of glycine metabolism
0.000 0.490 0.509
E72.4 Disorders of ornithine metabolism
0.000 0.490 0.509
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.490 0.509
E72.2 Disorders of urea cycle metabolism
0.000 0.490 0.509
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.490 0.509
E72.0 Disorders of amino-acid transport
0.000 0.490 0.509
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.490 0.509
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.490 0.509
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.490 0.509
E76.2 Other mucopolysaccharidoses
0.000 0.490 0.509
E76.1 Mucopolysaccharidosis, type II
0.000 0.490 0.509
E76.0 Mucopolysaccharidosis, type I
0.000 0.490 0.509
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.490 0.509
E77.8 Other disorders of glycoprotein metabolism
0.000 0.490 0.509
E77.1 Defects in glycoprotein degradation
0.000 0.490 0.509
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.490 0.509
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.498 0.502
E84.8 Cystic fibrosis with other manifestations
0.000 0.499 0.501
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.499 0.501
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.499 0.501
C93 Monocytic leukaemia
0.001 0.500 0.499
E84.9 Cystic fibrosis, unspecified
0.000 0.510 0.489
E88.8 Other specified metabolic disorders
0.000 0.512 0.488
C84.4 Peripheral T-cell lymphoma
0.000 0.512 0.488
E88.2 Lipomatosis, not elsewhere classified
0.000 0.514 0.486
E11.6 With other specified complications
0.000 0.517 0.483
C84.5 Other and unspecified T-cell lymphomas
0.000 0.518 0.482
C83.1 Small cleaved cell (diffuse)
0.000 0.519 0.480
E75.6 Lipid storage disorder, unspecified
0.000 0.521 0.479
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.521 0.479
E75.3 Sphingolipidosis, unspecified
0.000 0.521 0.479
E75.2 Other sphingolipidosis
0.000 0.521 0.479
E75.1 Other gangliosidosis
0.000 0.521 0.479
E75.0 GM2 gangliosidosis
0.000 0.521 0.479
K90.3 Pancreatic steatorrhoea
0.000 0.521 0.479
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.521 0.479
K90.1 Tropical sprue
0.000 0.521 0.479
K90.8 Other intestinal malabsorption
0.000 0.527 0.473
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.527 0.473
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.527 0.473
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.527 0.473
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.527 0.473
C84.3 Lymphoepithelioid lymphoma
0.000 0.527 0.473
C84.2 T-zone lymphoma
0.000 0.527 0.473
C84.1 Sezary's diease
0.000 0.527 0.473
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.467 0.533 0.000
E88.3 Tumour lysis syndrome
0.000 0.538 0.461
E88.9 Metabolic disorder, unspecified
0.000 0.546 0.453
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.547 0.452
C88 Malignant immunoproliferative diseases
0.001 0.547 0.452
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.551 0.448
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.554 0.446
E11.4 With neurological complications
0.000 0.558 0.442
E75.5 Other lipid storage disorders
0.000 0.563 0.437
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.567 0.432
C86.4 Blastic NK-cell lymphoma
0.000 0.567 0.432
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.567 0.432
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.567 0.432
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.567 0.432
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.567 0.432
G36.0 Neuromyelitis optica [Devic]
0.427 0.572 0.000
C81 Hodgkin's disease
0.000 0.574 0.425
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.579 0.421
C96.8 Histiocytic sarcoma
0.000 0.579 0.421
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.579 0.421
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.579 0.421
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.579 0.421
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.579 0.421
C96.3 True histiocytic lymphoma
0.000 0.579 0.421
C96.2 Malignant mast cell tumour
0.000 0.579 0.421
C96.1 Malignant histiocytosis
0.000 0.579 0.421
C96.0 Letterer-Siwe disease
0.000 0.579 0.421
E44.1 Mild protein-energy malnutrition
0.000 0.580 0.420
E44.0 Moderate protein-energy malnutrition
0.000 0.580 0.420
C83.0 Small cell (diffuse)
0.000 0.589 0.411
E85 Amyloidosis
0.001 0.589 0.411
G36.9 Acute disseminated demyelination, unspecified
0.407 0.593 0.000
G36.8 Other specified acute disseminated demyelination
0.407 0.593 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.407 0.593 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.597 0.403
C94.7 Other specified leukaemias
0.000 0.611 0.389
C94.5 Acute myelofibrosis
0.000 0.611 0.389
C94.4 Acute panmyelosis
0.000 0.611 0.389
C94.3 Mast cell leukaemia
0.000 0.611 0.389
C94.2 Acute megakaryoblastic leukaemia
0.000 0.611 0.389
C94.1 Chronic erythraemia
0.000 0.611 0.389
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.611 0.389
E89.4 Postprocedural ovarian failure
0.000 0.620 0.380
C95 Leukaemia of unspecified cell type
0.001 0.623 0.376
E73.8 Other lactose intolerance
0.001 0.624 0.375
E73.1 Secondary lactase deficiency
0.001 0.624 0.375
E73.0 Congenital lactase deficiency
0.001 0.624 0.375
E06 Thyroiditis
0.000 0.627 0.373
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.640 0.360
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.640 0.360
E89.5 Postprocedural testicular hypofunction
0.000 0.640 0.360
E89.1 Postprocedural hypoinsulinaemia
0.000 0.640 0.360
C93.9 Monocytic leukaemia, unspecified
0.001 0.641 0.358
C93.7 Other monocytic leukaemia
0.001 0.641 0.358
C93.3 Juvenile myelomonocytic leukaemia
0.001 0.641 0.358
C93.2 Subacute monocytic leukaemia
0.001 0.641 0.358
C93.0 Acute monocytic leukaemia
0.001 0.641 0.358
E11.3 With ophthalmic complications
0.000 0.650 0.350
E89.3 Postprocedural hypopituitarism
0.000 0.650 0.349
C91 Lymphoid leukaemia
0.001 0.652 0.347
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.001 0.655 0.344
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.001 0.656 0.343
E65-E68 Obesity and other hyperalimentation
0.000 0.661 0.339
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.663 0.337
C88.9 Malignant immunoproliferative disease, unspecified
0.001 0.675 0.324
C88.7 Other malignant immunoproliferative diseases
0.001 0.675 0.324
C88.3 Immunoproliferative small intestinal disease
0.001 0.675 0.324
C88.2 Gamma heavy chain disease
0.001 0.675 0.324
C88.1 Alpha heavy chain disease
0.001 0.675 0.324
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.001 0.689 0.310
E89.2 Postprocedural hypoparathyroidism
0.000 0.693 0.307
C81.0 Lymphocytic predominance
0.000 0.694 0.305
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.695 0.305
C81.3 Lymphocytic depletion
0.000 0.695 0.305
C91.9 Lymphoid leukaemia, unspecified
0.000 0.697 0.302
C92 Myeloid leukaemia
0.000 0.700 0.300
C81.7 Other Hodgkin's disease
0.000 0.703 0.296
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.705 0.294
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.705 0.294
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.705 0.294
C81.2 Mixed cellularity
0.000 0.708 0.292
L40 Psoriasis
0.000 0.722 0.278
E06.5 Other chronic thyroiditis
0.000 0.723 0.276
E85.8 Other amyloidosis
0.001 0.726 0.273
C93.1 Chronic monocytic leukaemia
0.001 0.729 0.270
C95.7 Other leukaemia of unspecified cell type
0.001 0.729 0.270
C95.2 Subacute leukaemia of unspecified cell type
0.001 0.729 0.270
E20-E35 Disorders of other endocrine glands
0.000 0.730 0.270
E06.4 Drug-induced thyroiditis
0.000 0.732 0.267
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.732 0.267
E06.0 Acute thyroiditis
0.000 0.732 0.267
C81.9 Hodgkin's disease, unspecified
0.000 0.737 0.263
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.745 0.255
E85.9 Amyloidosis, unspecified
0.001 0.748 0.252
E28 Ovarian dysfunction
0.000 0.749 0.251
C91.8 Mature B-cell leukaemia Burkitt-type
0.001 0.750 0.249
C91.7 Other lymphoid leukaemia
0.001 0.750 0.249
C91.6 Prolymphocytic leukaemia of T-cell type
0.001 0.750 0.249
C91.3 Prolymphocytic leukaemia
0.001 0.750 0.249
C91.2 Subacute lymphocytic leukaemia
0.001 0.750 0.249
C81.1 Nodular sclerosis
0.000 0.750 0.249
E85.4 Organ-limited amyloidosis
0.001 0.751 0.248
E28.2 Polycystic ovarian syndrome
0.000 0.755 0.245
E67 Other hyperalimentation
0.000 0.757 0.243
E68 Sequelae of hyperalimentation
0.000 0.757 0.243
M06.9 Rheumatoid arthritis, unspecified
0.000 0.760 0.240
C91.5 Adult T-cell leukaemia
0.001 0.761 0.239
E06.1 Subacute thyroiditis
0.001 0.763 0.236
C95.1 Chronic leukaemia of unspecified cell type
0.001 0.765 0.234
L40.8 Other psoriasis
0.000 0.772 0.228
E85.3 Secondary systemic amyloidosis
0.001 0.772 0.227
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.773 0.226
E24 Cushing's syndrome
0.000 0.773 0.226
C95.9 Leukaemia, unspecified
0.001 0.780 0.219
C95.0 Acute leukaemia of unspecified cell type
0.001 0.783 0.216
E50-E64 Other nutritional deficiencies
0.000 0.783 0.216
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.784 0.215
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.784 0.215
C92.5 Acute myelomonocytic leukaemia
0.000 0.784 0.215
C92.3 Myeloid sarcoma
0.000 0.784 0.215
C92.2 Subacute myeloid leukaemia
0.000 0.784 0.215
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.787 0.213
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.788 0.212
C92.7 Other myeloid leukaemia
0.000 0.789 0.210
C92.9 Myeloid leukaemia, unspecified
0.000 0.790 0.209
L40.1 Generalised pustular psoriasis
0.000 0.796 0.203
C92.4 Acute promyelocytic leukaemia
0.000 0.797 0.202
C90 Multiple myeloma and malignant plasma cell neoplasms
0.021 0.799 0.180
L40.4 Guttate psoriasis
0.000 0.800 0.200
L40.2 Acrodermatitis continua
0.000 0.800 0.200
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.802 0.198
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.804 0.196
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.806 0.194
E32 Diseases of thymus
0.000 0.806 0.194
E31 Polyglandular dysfunction
0.000 0.806 0.194
E30 Disorders of puberty, not elsewhere classified
0.000 0.806 0.194
E25 Adrenogenital disorders
0.000 0.806 0.194
E24.0 Pituitary-dependent Cushing's disease
0.000 0.809 0.191
C91.1 Chronic lymphocytic leukaemia
0.000 0.810 0.190
E73.9 Lactose intolerance, unspecified
0.001 0.811 0.188
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.811 0.189
C91.0 Acute lymphoblastic leukaemia
0.001 0.812 0.188
C92.1 Chronic myeloid leukaemia
0.000 0.812 0.187
E26 Hyperaldosteronism
0.000 0.813 0.187
L40.0 Psoriasis vulgaris
0.000 0.814 0.186
E65 Localised adiposity
0.000 0.814 0.186
E28.9 Ovarian dysfunction, unspecified
0.000 0.820 0.180
E28.8 Other ovarian dysfunction
0.000 0.820 0.180
E28.1 Androgen excess
0.000 0.820 0.180
E28.0 Oestrogen excess
0.000 0.820 0.180
E06.9 Thyroiditis, unspecified
0.001 0.821 0.179
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.825 0.175
E67.8 Other specified hyperalimentation
0.000 0.825 0.174
E67.3 Hypervitaminosis D
0.000 0.825 0.174
E67.2 Megavitamin-B6 syndrome
0.000 0.825 0.174
E67.1 Hypercarotenaemia
0.000 0.825 0.174
E67.0 Hypervitaminosis A
0.000 0.825 0.174
E24.9 Cushing's syndrome, unspecified
0.000 0.831 0.169
L40.3 Pustulosis palmaris et plantaris
0.000 0.831 0.169
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.832 0.167
E06.3 Autoimmune thyroiditis
0.000 0.835 0.165
E24.2 Drug-induced Cushing's syndrome
0.000 0.837 0.163
E24.8 Other Cushing's syndrome
0.000 0.837 0.162
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.837 0.162
E24.3 Ectopic ACTH syndrome
0.000 0.837 0.162
E24.1 Nelson's syndrome
0.000 0.837 0.162
I25.1 Atherosclerotic heart disease
0.000 0.837 0.163
I25 Chronic ischaemic heart disease
0.000 0.838 0.162
E20 Hypoparathyroidism
0.000 0.840 0.160
I25.5 Ischaemic cardiomyopathy
0.000 0.843 0.157
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.844 0.156
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.844 0.155
E63 Other nutritional deficiencies
0.000 0.844 0.155
E50 Vitamin A deficiency
0.000 0.844 0.155
E60 Dietary zinc deficiency
0.000 0.844 0.155
E59 Dietary selenium deficiency
0.000 0.844 0.155
E54 Ascorbic acid deficiency
0.000 0.844 0.155
E52 Niacin deficiency [pellagra]
0.000 0.844 0.155
E29 Testicular dysfunction
0.000 0.845 0.155
E56 Other vitamin deficiencies
0.000 0.845 0.154
E23 Hypofunction and other disorders of pituitary gland
0.000 0.847 0.153
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.849 0.151
I25.2 Old myocardial infarction
0.000 0.850 0.150
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.855 0.145
E51 Thiamine deficiency
0.000 0.856 0.144
L40.5 Arthropathic psoriasis
0.000 0.857 0.143
E58 Dietary calcium deficiency
0.000 0.858 0.141
C90.3 Solitary plasmacytoma
0.015 0.859 0.126
C90.1 Plasma cell leukaemia
0.015 0.859 0.126
C88.0 Waldenstrom's macroglobulinaemia
0.002 0.860 0.138
E25.9 Adrenogenital disorder, unspecified
0.000 0.861 0.139
E25.8 Other adrenogenital disorders
0.000 0.861 0.139
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.861 0.139
E30.9 Disorder of puberty, unspecified
0.000 0.861 0.139
E30.8 Other disorders of puberty
0.000 0.861 0.139
E30.1 Precocious puberty
0.000 0.861 0.139
E30.0 Delayed puberty
0.000 0.861 0.139
E31.9 Polyglandular dysfunction, unspecified
0.000 0.861 0.139
E31.8 Other polyglandular dysfunction
0.000 0.861 0.139
E31.1 Polyglandular hyperfunction
0.000 0.861 0.139
E31.0 Autoimmune polyglandular failure
0.000 0.861 0.139
E32.9 Disease of thymus, unspecified
0.000 0.861 0.139
E32.8 Other diseases of thymus
0.000 0.861 0.139
E32.1 Abscess of thymus
0.000 0.861 0.139
E32.0 Persistent hyperplasia of thymus
0.000 0.861 0.139
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.861 0.139
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.861 0.139
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.861 0.139
E34 Other endocrine disorders
0.001 0.863 0.137
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.863 0.137
E26.9 Hyperaldosteronism, unspecified
0.000 0.866 0.134
E26.8 Other hyperaldosteronism
0.000 0.866 0.134
E26.1 Secondary hyperaldosteronism
0.000 0.866 0.134
E26.0 Primary hyperaldosteronism
0.000 0.872 0.128
M06 Other rheumatoid arthritis
0.000 0.874 0.126
E61 Deficiency of other nutrient elements
0.000 0.875 0.125
E28.3 Primary ovarian failure
0.000 0.878 0.121
E21.3 Hyperparathyroidism, unspecified
0.000 0.880 0.120
L40-L45 Papulosquamous disorders
0.000 0.881 0.119
I25.6 Silent myocardial ischaemia
0.000 0.884 0.116
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.884 0.116
E20.8 Other hypoparathyroidism
0.000 0.885 0.115
E20.1 Pseudohypoparathyroidism
0.000 0.885 0.115
E20.0 Idiopathic hypoparathyroidism
0.000 0.885 0.115
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.886 0.114
E23.2 Diabetes insipidus
0.000 0.886 0.114
E22 Hyperfunction of pituitary gland
0.000 0.887 0.113
E50.9 Vitamin A deficiency, unspecified
0.000 0.888 0.111
E50.8 Other manifestations of vitamin A deficiency
0.000 0.888 0.111
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.888 0.111
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.888 0.111
E50.5 Vitamin A deficiency with night blindness
0.000 0.888 0.111
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.888 0.111
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.888 0.111
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.888 0.111
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.888 0.111
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.888 0.111
E63.9 Nutritional deficiency, unspecified
0.000 0.888 0.111
E63.8 Other specified nutritional deficiencies
0.000 0.888 0.111
E63.1 Imbalance of constituents of food intake
0.000 0.888 0.111

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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