TreeWAS – Variant ID: rs2286656

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
L40 Psoriasis	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.004	0.996
E10-E14 Diabetes mellitus	0.000	0.005	0.995
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.006	0.994
L40.0 Psoriasis vulgaris	0.992	0.008	0.000
E10.4 With neurological complications	0.000	0.029	0.971
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.048	0.952
E10.3 With ophthalmic complications	0.000	0.077	0.923
E16 Other disorders of pancreatic internal secretion	0.000	0.078	0.922
E10.5 With peripheral circulatory complications	0.000	0.089	0.911
E16.2 Hypoglycaemia, unspecified	0.000	0.099	0.901
E50-E64 Other nutritional deficiencies	0.000	0.104	0.896
L40.1 Generalised pustular psoriasis	0.850	0.150	0.000
L40.8 Other psoriasis	0.847	0.153	0.000
E10.1 With ketoacidosis	0.000	0.153	0.847
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.847	0.153	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.844	0.156	0.000
E07 Other disorders of thyroid	0.000	0.158	0.842
T43.2 Other and unspecified antidepressants	0.837	0.163	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.833	0.167	0.000
E06 Thyroiditis	0.000	0.171	0.829
E10.2 With renal complications	0.000	0.171	0.829
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.188	0.812
E55 Vitamin D deficiency	0.000	0.196	0.804
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.780	0.220	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.226	0.774
T43.0 Tricyclic and tetracyclic antidepressants	0.773	0.227	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.767	0.233	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.756	0.244	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.748	0.252	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.747	0.253	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.740	0.260	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.261	0.739
M07.3 Other psoriatic arthropathies	0.739	0.261	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.264	0.736
M07.39 Other psoriatic arthropathies (Site unspecified)	0.730	0.270	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.723	0.277	0.000
E05.8 Other thyrotoxicosis	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E10.7 With multiple complications	0.000	0.283	0.717
E10.6 With other specified complications	0.000	0.283	0.717
E10.0 With coma	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.286	0.713
T43.6 Psychostimulants with abuse potential	0.710	0.290	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.293	0.707
E53 Deficiency of other B group vitamins	0.000	0.296	0.704
E06.3 Autoimmune thyroiditis	0.000	0.306	0.694
T46 Poisoning by agents primarily affecting the cardiovascular system	0.686	0.314	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.317	0.683
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.680	0.320	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.661	0.338	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.339	0.661
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.339	0.661
E16.4 Abnormal secretion of gastrin	0.000	0.339	0.661
E16.3 Increased secretion of glucagon	0.000	0.339	0.661
E10.8 With unspecified complications	0.000	0.343	0.657
T47.1 Other antacids and anti-gastric-secretion drugs	0.651	0.349	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.650	0.350	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.648	0.352	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.647	0.353	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.646	0.354	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.357	0.642
E63 Other nutritional deficiencies	0.000	0.357	0.642
E56 Other vitamin deficiencies	0.000	0.357	0.642
E51 Thiamine deficiency	0.000	0.357	0.642
E50 Vitamin A deficiency	0.000	0.357	0.642
E60 Dietary zinc deficiency	0.000	0.357	0.642
E59 Dietary selenium deficiency	0.000	0.357	0.642
E58 Dietary calcium deficiency	0.000	0.357	0.642
E54 Ascorbic acid deficiency	0.000	0.357	0.642
E52 Niacin deficiency [pellagra]	0.000	0.357	0.642
E61 Deficiency of other nutrient elements	0.000	0.364	0.636
E13 Other specified diabetes mellitus	0.000	0.365	0.635
E03.8 Other specified hypothyroidism	0.000	0.370	0.630
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.629	0.371	0.000
T45.0 Antiallergic and antiemetic drugs	0.627	0.372	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.624	0.376	0.000
E06.9 Thyroiditis, unspecified	0.000	0.383	0.617
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.613	0.387	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.610	0.390	0.000
T43.9 Psychotropic drug, unspecified	0.607	0.393	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.607	0.393	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.607	0.393	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.606	0.394	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.605	0.395	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.605	0.395	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.605	0.395	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.605	0.395	0.000
E07.1 Dyshormogenetic goitre	0.000	0.396	0.603
E07.0 Hypersecretion of calcitonin	0.000	0.396	0.603
T36 Poisoning by systemic antibiotics	0.601	0.399	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.597	0.403	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.597	0.403	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.597	0.403	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.597	0.403	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.597	0.403	0.000
T44.0 Anticholinesterase agents	0.597	0.403	0.000
E06.5 Other chronic thyroiditis	0.000	0.405	0.595
E06.4 Drug-induced thyroiditis	0.000	0.405	0.595
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.405	0.595
E06.1 Subacute thyroiditis	0.000	0.405	0.595
E06.0 Acute thyroiditis	0.000	0.405	0.595
T47.4 Other laxatives	0.593	0.407	0.000
E16.1 Other hypoglycaemia	0.000	0.416	0.584
E55.0 Rickets, active	0.000	0.423	0.577
E53.8 Deficiency of other specified B group vitamins	0.000	0.434	0.566
T46.4 Angiotensin-converting-enzyme inhibitors	0.563	0.437	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.445	0.555
T45.1 Antineoplastic and immunosuppressive drugs	0.538	0.462	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.536	0.464	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.536	0.464	0.000
T42.3 Barbiturates	0.536	0.464	0.000
T42.2 Succinimides and oxazolidinediones	0.536	0.464	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.535	0.465	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.535	0.465	0.000
T47.7 Emetics	0.535	0.465	0.000
T47.6 Antidiarrhoeal drugs	0.535	0.465	0.000
T47.5 Digestants	0.535	0.465	0.000
T47.3 Saline and osmotic laxatives	0.535	0.465	0.000
T47.2 Stimulant laxatives	0.535	0.465	0.000
T47.0 Histamine H(2)-receptor antagonists	0.535	0.465	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.532	0.468	0.000
M07.38 Other psoriatic arthropathies (Other)	0.529	0.470	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.529	0.470	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.529	0.470	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.529	0.470	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.529	0.470	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.518	0.481	0.000
T45.8 Other primarily systemic and haematological agents	0.518	0.481	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.518	0.481	0.000
T45.6 Fibrinolysis-affecting drugs	0.518	0.481	0.000
T45.5 Anticoagulants	0.518	0.481	0.000
T45.4 Iron and its compounds	0.518	0.481	0.000
T45.3 Enzymes, not elsewhere classified	0.518	0.481	0.000
T45.2 Vitamins, not elsewhere classified	0.518	0.481	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E40-E46 Malnutrition	0.001	0.486	0.514
T39.0 Salicylates	0.513	0.487	0.000
E12.9 Without complications	0.000	0.488	0.512
E12.8 With unspecified complications	0.000	0.488	0.512
E12.7 With multiple complications	0.000	0.488	0.512
E12.6 With other specified complications	0.000	0.488	0.512
E12.5 With peripheral circulatory complications	0.000	0.488	0.512
E12.4 With neurological complications	0.000	0.488	0.512
E12.3 With ophthalmic complications	0.000	0.488	0.512
E12.2 With renal complications	0.000	0.488	0.512
E12.1 With ketoacidosis	0.000	0.488	0.512
E12.0 With coma	0.000	0.488	0.512
T42.1 Iminostilbenes	0.511	0.489	0.000
T39.1 4-Aminophenol derivatives	0.507	0.493	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.495	0.505
E53.1 Pyridoxine deficiency	0.000	0.495	0.505
E53.0 Riboflavin deficiency	0.000	0.495	0.505
T42.0 Hydantoin derivatives	0.504	0.496	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.504	0.496	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.493	0.507	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.492	0.508	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.492	0.508	0.000
T46.7 Peripheral vasodilators	0.492	0.508	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.492	0.508	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.492	0.508	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.492	0.508	0.000
T46.1 Calcium-channel blockers	0.488	0.512	0.000
T38.1 Thyroid hormones and substitutes	0.486	0.514	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.474	0.526	0.000
T38.9 Other and unspecified hormone antagonists	0.466	0.534	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.466	0.534	0.000
T38.7 Androgens and anabolic congeners	0.466	0.534	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.466	0.534	0.000
T38.5 Other oestrogens and progestogens	0.466	0.534	0.000
T38.4 Oral contraceptives	0.466	0.534	0.000
T38.2 Antithyroid drugs	0.466	0.534	0.000
T38.0 Glucocorticoids and synthetic analogues	0.466	0.534	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.464	0.536	0.000
T50.8 Diagnostic agents	0.463	0.537	0.000
T50.7 Analeptics and opioid receptor antagonists	0.463	0.537	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.463	0.537	0.000
T50.5 Appetite depressants	0.463	0.537	0.000
T50.4 Drugs affecting uric acid metabolism	0.463	0.537	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.463	0.537	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.463	0.537	0.000
T50.1 Loop [high-ceiling] diuretics	0.463	0.537	0.000
T50.0 Mineralocorticoids and their antagonists	0.463	0.537	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.539	0.461
E50.8 Other manifestations of vitamin A deficiency	0.000	0.539	0.461
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.539	0.461
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.539	0.461
E50.5 Vitamin A deficiency with night blindness	0.000	0.539	0.461
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.539	0.461
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.539	0.461
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.539	0.461
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.539	0.461
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.539	0.461
E51.9 Thiamine deficiency, unspecified	0.000	0.539	0.461
E51.8 Other manifestations of thiamine deficiency	0.000	0.539	0.461
E51.2 Wernicke's encephalopathy	0.000	0.539	0.461
E51.1 Beriberi	0.000	0.539	0.461
E56.9 Vitamin deficiency, unspecified	0.000	0.539	0.461
E56.8 Deficiency of other vitamins	0.000	0.539	0.461
E56.1 Deficiency of vitamin K	0.000	0.539	0.461
E56.0 Deficiency of vitamin E	0.000	0.539	0.461
E63.9 Nutritional deficiency, unspecified	0.000	0.539	0.461
E63.8 Other specified nutritional deficiencies	0.000	0.539	0.461
E63.1 Imbalance of constituents of food intake	0.000	0.539	0.461
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.539	0.461
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.539	0.461
E64.8 Sequelae of other nutritional deficiencies	0.000	0.539	0.461
E64.3 Sequelae of rickets	0.000	0.539	0.461
E64.2 Sequelae of vitamin C deficiency	0.000	0.539	0.461
E64.1 Sequelae of vitamin A deficiency	0.000	0.539	0.461
E64.0 Sequelae of protein-energy malnutrition	0.000	0.539	0.461
K90 Intestinal malabsorption	0.000	0.542	0.458
E61.9 Deficiency of nutrient element, unspecified	0.000	0.544	0.456
E61.8 Deficiency of other specified nutrient elements	0.000	0.544	0.456
E61.7 Deficiency of multiple nutrient elements	0.000	0.544	0.456
E61.6 Vanadium deficiency	0.000	0.544	0.456
E61.5 Molybdenum deficiency	0.000	0.544	0.456
E61.4 Chromium deficiency	0.000	0.544	0.456
E61.3 Manganese deficiency	0.000	0.544	0.456
E61.2 Magnesium deficiency	0.000	0.544	0.456
E61.0 Copper deficiency	0.000	0.544	0.456
E13.8 With unspecified complications	0.000	0.544	0.456
E13.7 With multiple complications	0.000	0.544	0.456
E13.6 With other specified complications	0.000	0.544	0.456
E13.5 With peripheral circulatory complications	0.000	0.544	0.456
E13.4 With neurological complications	0.000	0.544	0.456
E13.3 With ophthalmic complications	0.000	0.544	0.456
E13.2 With renal complications	0.000	0.544	0.456
E13.1 With ketoacidosis	0.000	0.544	0.456
E13.0 With coma	0.000	0.544	0.456
T42.4 Benzodiazepines	0.455	0.545	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.450	0.550	0.000
E61.1 Iron deficiency	0.000	0.551	0.449
E07.8 Other specified disorders of thyroid	0.000	0.555	0.445
T39.4 Antirheumatics, not elsewhere classified	0.438	0.562	0.000
T39.2 Pyrazolone derivatives	0.438	0.562	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.434	0.566	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.434	0.566	0.000
T37.5 Antiviral drugs	0.434	0.566	0.000
T37.4 Anthelminthics	0.434	0.566	0.000
T37.3 Other antiprotozoal drugs	0.434	0.566	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.434	0.566	0.000
T37.1 Antimycobacterial drugs	0.434	0.566	0.000
T37.0 Sulphonamides	0.434	0.566	0.000
T41.5 Therapeutic gases	0.434	0.566	0.000
T41.4 Anaesthetic, unspecified	0.434	0.566	0.000
T41.3 Local anaesthetics	0.434	0.566	0.000
T41.2 Other and unspecified general anaesthetics	0.434	0.566	0.000
T41.1 Intravenous anaesthetics	0.434	0.566	0.000
T41.0 Inhaled anaesthetics	0.434	0.566	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.434	0.566	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.434	0.566	0.000
T48.5 Anti-common-cold drugs	0.434	0.566	0.000
T48.4 Expectorants	0.434	0.566	0.000
T48.3 Antitussives	0.434	0.566	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.434	0.566	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.434	0.566	0.000
T48.0 Oxytocic drugs	0.434	0.566	0.000
T49.9 Topical agent, unspecified	0.434	0.566	0.000
T49.8 Other topical agents	0.434	0.566	0.000
T49.7 Dental drugs, topically applied	0.434	0.566	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.434	0.566	0.000
T49.5 Ophthalmological drugs and preparations	0.434	0.566	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.434	0.566	0.000
T49.3 Emollients, demulcents and protectants	0.434	0.566	0.000
T49.2 Local astringents and local detergents	0.434	0.566	0.000
T49.1 Antipruritics	0.434	0.566	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.434	0.566	0.000
T36.9 Systemic antibiotic, unspecified	0.431	0.569	0.000
T36.8 Other systemic antibiotics	0.431	0.569	0.000
T36.7 Antifungal antibiotics, systemically used	0.431	0.569	0.000
T36.6 Rifamycins	0.431	0.569	0.000
T36.5 Aminoglycosides	0.431	0.569	0.000
T36.4 Tetracyclines	0.431	0.569	0.000
T36.3 Macrolides	0.431	0.569	0.000
T36.2 Chloramphenicol group	0.431	0.569	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.431	0.569	0.000
T36.0 Penicillins	0.427	0.573	0.000
E67 Other hyperalimentation	0.000	0.602	0.398
E68 Sequelae of hyperalimentation	0.000	0.602	0.398
E20-E35 Disorders of other endocrine glands	0.000	0.603	0.397
E14 Unspecified diabetes mellitus	0.000	0.612	0.388
E13.9 Without complications	0.000	0.622	0.377
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.630	0.370
E44 Protein-energy malnutrition of moderate and mild degree	0.001	0.631	0.368
E45 Retarded development following protein-energy malnutrition	0.001	0.631	0.368
E43 Unspecified severe protein-energy malnutrition	0.001	0.631	0.368
E42 Marasmic kwashiorkor	0.001	0.631	0.368
E41 Nutritional marasmus	0.001	0.631	0.368
E40 Kwashiorkor	0.001	0.631	0.368
E27 Other disorders of adrenal gland	0.000	0.637	0.363
E27.1 Primary adrenocortical insufficiency	0.000	0.645	0.355
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.349	0.650	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.652	0.348
E66 Obesity	0.000	0.657	0.343
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.342	0.658	0.000
E04 Other non-toxic goitre	0.000	0.667	0.333
K90.3 Pancreatic steatorrhoea	0.000	0.671	0.329
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.671	0.329
K90.1 Tropical sprue	0.000	0.671	0.329
E65 Localised adiposity	0.000	0.679	0.321
M07 Psoriatic and enteropathic arthropathies	0.319	0.681	0.000
E66.8 Other obesity	0.000	0.688	0.312
E14.3 With ophthalmic complications	0.000	0.691	0.308
E34 Other endocrine disorders	0.000	0.712	0.288
E67.8 Other specified hyperalimentation	0.000	0.714	0.286
E67.3 Hypervitaminosis D	0.000	0.714	0.286
E67.2 Megavitamin-B6 syndrome	0.000	0.714	0.286
E67.1 Hypercarotenaemia	0.000	0.714	0.286
E67.0 Hypervitaminosis A	0.000	0.714	0.286
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.715	0.285
E32 Diseases of thymus	0.000	0.715	0.285
E31 Polyglandular dysfunction	0.000	0.715	0.285
E30 Disorders of puberty, not elsewhere classified	0.000	0.715	0.285
E25 Adrenogenital disorders	0.000	0.715	0.285
E22 Hyperfunction of pituitary gland	0.000	0.721	0.279
E27.8 Other specified disorders of adrenal gland	0.000	0.721	0.279
E14.7 With multiple complications	0.000	0.721	0.278
E14.6 With other specified complications	0.000	0.721	0.278
E14.5 With peripheral circulatory complications	0.000	0.721	0.278
E14.2 Withrenal complications	0.000	0.721	0.278
E14.0 With coma	0.000	0.721	0.278
E20 Hypoparathyroidism	0.000	0.732	0.268
E14.8 With unspecified complications	0.000	0.732	0.267
E44.1 Mild protein-energy malnutrition	0.001	0.735	0.264
E44.0 Moderate protein-energy malnutrition	0.001	0.735	0.264
E14.1 With ketoacidosis	0.000	0.736	0.264
E28 Ovarian dysfunction	0.000	0.738	0.262
E27.5 Adrenomedullary hyperfunction	0.000	0.739	0.261
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.739	0.261
E27.0 Other adrenocortical overactivity	0.000	0.739	0.261
E27.2 Addisonian crisis	0.000	0.744	0.256
E26 Hyperaldosteronism	0.000	0.746	0.254
E29 Testicular dysfunction	0.000	0.747	0.253
L40-L45 Papulosquamous disorders	0.252	0.747	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.251	0.749	0.000
T40.8 Lysergide [LSD]	0.251	0.749	0.000
T40.7 Cannabis (derivatives)	0.251	0.749	0.000
T40.5 Cocaine	0.251	0.749	0.000
T40.3 Methadone	0.251	0.749	0.000
T40.1 Heroin	0.251	0.749	0.000
T40.0 Opium	0.251	0.749	0.000
K90.8 Other intestinal malabsorption	0.000	0.750	0.249
E66.1 Drug-induced obesity	0.000	0.754	0.246
E04.8 Other specified non-toxic goitre	0.000	0.761	0.238
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.764	0.236
E04.9 Non-toxic goitre, unspecified	0.000	0.765	0.235
E22.1 Hyperprolactinaemia	0.000	0.768	0.232
E24 Cushing's syndrome	0.000	0.768	0.232
T40.4 Other synthetic narcotics	0.231	0.769	0.000
M07.6 Other enteropathic arthropathies	0.229	0.771	0.000
M07.5 Arthropathy in ulcerative colitis	0.229	0.771	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.229	0.771	0.000
M07.2 Psoriatic spondylitis	0.229	0.771	0.000
M07.1 Arthritis mutilans	0.229	0.771	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.229	0.771	0.000
E14.4 With neurological complications	0.000	0.776	0.224
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.781	0.218
E34.9 Endocrine disorder, unspecified	0.000	0.787	0.213
E34.0 Carcinoid syndrome	0.000	0.790	0.210
T40.6 Other and unspecified narcotics	0.207	0.792	0.000
E34.5 Androgen resistance syndrome	0.000	0.793	0.207
E34.4 Constitutional tall stature	0.000	0.793	0.207
E34.3 Short stature, not elsewhere classified	0.000	0.793	0.207
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.793	0.207
E34.1 Other hypersecretion of intestinal hormones	0.000	0.793	0.207
E25.9 Adrenogenital disorder, unspecified	0.000	0.796	0.204
E25.8 Other adrenogenital disorders	0.000	0.796	0.204
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.796	0.204
E30.9 Disorder of puberty, unspecified	0.000	0.796	0.204
E30.8 Other disorders of puberty	0.000	0.796	0.204
E30.1 Precocious puberty	0.000	0.796	0.204
E30.0 Delayed puberty	0.000	0.796	0.204
E31.9 Polyglandular dysfunction, unspecified	0.000	0.796	0.204
E31.8 Other polyglandular dysfunction	0.000	0.796	0.204
E31.1 Polyglandular hyperfunction	0.000	0.796	0.204
E31.0 Autoimmune polyglandular failure	0.000	0.796	0.204
E32.9 Disease of thymus, unspecified	0.000	0.796	0.204
E32.8 Other diseases of thymus	0.000	0.796	0.204
E32.1 Abscess of thymus	0.000	0.796	0.204
E32.0 Persistent hyperplasia of thymus	0.000	0.796	0.204
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.796	0.204
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.796	0.204
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.796	0.204
E66.0 Obesity due to excess calories	0.000	0.796	0.204
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.204	0.796	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.799	0.201
E34.8 Other specified endocrine disorders	0.000	0.799	0.201
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.800	0.200
E22.8 Other hyperfunction of pituitary gland	0.000	0.800	0.200
E04.0 Non-toxic diffuse goitre	0.000	0.801	0.199
E28.3 Primary ovarian failure	0.000	0.802	0.198
E20.8 Other hypoparathyroidism	0.000	0.807	0.192
E20.1 Pseudohypoparathyroidism	0.000	0.807	0.192
E20.0 Idiopathic hypoparathyroidism	0.000	0.807	0.192
E28.9 Ovarian dysfunction, unspecified	0.000	0.812	0.188
E28.8 Other ovarian dysfunction	0.000	0.812	0.188
E28.1 Androgen excess	0.000	0.812	0.188
E28.0 Oestrogen excess	0.000	0.812	0.188
L42 Pityriasis rosea	0.187	0.813	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.818	0.182
E26.8 Other hyperaldosteronism	0.000	0.818	0.182
E26.1 Secondary hyperaldosteronism	0.000	0.818	0.182
E29.9 Testicular dysfunction, unspecified	0.000	0.818	0.182
E29.8 Other testicular dysfunction	0.000	0.818	0.182
E29.0 Testicular hyperfunction	0.000	0.818	0.182
L44 Other papulosquamous disorders	0.181	0.819	0.000
L41 Parapsoriasis	0.181	0.819	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.181	0.819	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.821	0.179
E04.1 Non-toxic single thyroid nodule	0.000	0.822	0.178
E20.9 Hypoparathyroidism, unspecified	0.000	0.824	0.176
E27.9 Disorder of adrenal gland, unspecified	0.000	0.825	0.175
E46 Unspecified protein-energy malnutrition	0.001	0.831	0.168
E21.0 Primary hyperparathyroidism	0.000	0.831	0.169
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.833	0.167
E24.8 Other Cushing's syndrome	0.000	0.833	0.166
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.833	0.166
E24.3 Ectopic ACTH syndrome	0.000	0.833	0.166
E24.2 Drug-induced Cushing's syndrome	0.000	0.833	0.166
E24.1 Nelson's syndrome	0.000	0.833	0.166
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.164	0.835	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.164	0.835	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.164	0.835	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.164	0.835	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.164	0.835	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.164	0.835	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.164	0.835	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.164	0.835	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.164	0.835	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.164	0.835	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.164	0.835	0.000
M07.18 Arthritis mutilans (Other)	0.164	0.835	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.164	0.835	0.000
M07.16 Arthritis mutilans (Lower leg)	0.164	0.835	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.164	0.835	0.000
M07.14 Arthritis mutilans (Hand)	0.164	0.835	0.000
M07.13 Arthritis mutilans (Forearm)	0.164	0.835	0.000
M07.12 Arthritis mutilans (Upper arm)	0.164	0.835	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.164	0.835	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.164	0.835	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.164	0.835	0.000
M07.28 Psoriatic spondylitis (Other)	0.164	0.835	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.164	0.835	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.164	0.835	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.164	0.835	0.000
M07.24 Psoriatic spondylitis (Hand)	0.164	0.835	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.164	0.835	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.164	0.835	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.164	0.835	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.164	0.835	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.164	0.835	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.164	0.835	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.164	0.835	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.164	0.835	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.164	0.835	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.164	0.835	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.164	0.835	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.164	0.835	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.164	0.835	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.164	0.835	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.164	0.835	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.164	0.835	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.164	0.835	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.164	0.835	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.164	0.835	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.164	0.835	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.164	0.835	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.164	0.835	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations