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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2290161
log Bayes Factor = 15.2998
Chromosome 3   position 12,633,168  (GRCh37) Explore rs2290161 on Ensembl!
Variant rs2290161 is part of Cluster X0232

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
R50-R69 General symptoms and signs
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
I60-I69 Cerebrovascular diseases
0.995 0.005 0.000
Chapter VIII Diseases of the ear and mastoid process
0.995 0.005 0.000
Chapter X Diseases of the respiratory system
0.993 0.007 0.000
R69 Unknown and unspecified causes of morbidity
0.985 0.015 0.000
M15-M19 Arthrosis
0.984 0.016 0.000
I30-I52 Other forms of heart disease
0.982 0.018 0.000
R63 Symptoms and signs concerning food and fluid intake
0.980 0.020 0.000
M17 Gonarthrosis [arthrosis of knee]
0.972 0.028 0.000
H90-H95 Other disorders of ear
0.971 0.029 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.970 0.030 0.000
I67 Other cerebrovascular diseases
0.968 0.032 0.000
Chapter V Mental and behavioural disorders
0.963 0.037 0.000
M17.9 Gonarthrosis, unspecified
0.959 0.041 0.000
M45-M49 Spondylopathies
0.955 0.045 0.000
Chapter XX External causes of morbidity and mortality
0.954 0.046 0.000
J09-J18 Influenza and pneumonia
0.952 0.048 0.000
I67.9 Cerebrovascular disease, unspecified
0.950 0.050 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.949 0.051 0.000
Chapter VI Diseases of the nervous system
0.946 0.054 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.942 0.058 0.000
R63.4 Abnormal weight loss
0.941 0.059 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.932 0.068 0.000
H91 Other hearing loss
0.929 0.071 0.000
J18 Pneumonia, organism unspecified
0.922 0.078 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.916 0.084 0.000
R51 Headache
0.910 0.090 0.000
H65-H75 Diseases of middle ear and mastoid
0.907 0.093 0.000
M20-M25 Other joint disorders
0.903 0.097 0.000
I34 Nonrheumatic mitral valve disorders
0.899 0.101 0.000
H91.9 Hearing loss, unspecified
0.898 0.102 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.898 0.102 0.000
M70-M79 Other soft tissue disorders
0.896 0.104 0.000
S40-S49 Injuries to the shoulder and upper arm
0.891 0.109 0.000
I51 Complications and ill-defined descriptions of heart disease
0.889 0.111 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.888 0.112 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.888 0.112 0.000
J18.9 Pneumonia, unspecified
0.888 0.112 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.886 0.114 0.000
Chapter XIV Diseases of the genitourinary system
0.885 0.115 0.000
M47 Spondylosis
0.882 0.118 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.879 0.121 0.000
R47-R49 Symptoms and signs involving speech and voice
0.879 0.121 0.000
M17.1 Other primary gonarthrosis
0.875 0.125 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.874 0.126 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.874 0.126 0.000
M20 Acquired deformities of fingers and toes
0.872 0.128 0.000
I49 Other cardiac arrhythmias
0.871 0.129 0.000
Chapter I Certain infectious and parasitic diseases
0.871 0.129 0.000
R63.0 Anorexia
0.871 0.129 0.000
I47 Paroxysmal tachycardia
0.871 0.129 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.866 0.134 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.864 0.136 0.000
R56 Convulsions, not elsewhere classified
0.859 0.141 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.859 0.141 0.000
H90 Conductive and sensorineural hearing loss
0.857 0.143 0.000
I69 Sequelae of cerebrovascular disease
0.857 0.143 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.855 0.145 0.000
I95 Hypotension
0.854 0.146 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.849 0.150 0.000
J90-J94 Other diseases of pleura
0.849 0.151 0.000
M50-M54 Other dorsopathies
0.845 0.155 0.000
M47.8 Other spondylosis
0.844 0.156 0.000
M40-M43 Deforming dorsopathies
0.839 0.161 0.000
R42 Dizziness and giddiness
0.835 0.165 0.000
I45 Other conduction disorders
0.835 0.165 0.000
I34.0 Mitral (valve) insufficiency
0.832 0.168 0.000
M79.6 Pain in limb
0.832 0.168 0.000
H80-H83 Diseases of inner ear
0.831 0.169 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.829 0.171 0.000
I95.1 Orthostatic hypotension
0.827 0.173 0.000
N10-N16 Renal tubulo-interstitial diseases
0.827 0.173 0.000
I62 Other nontraumatic intracranial haemorrhage
0.822 0.178 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.822 0.178 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.821 0.179 0.000
R26 Abnormalities of gait and mobility
0.820 0.180 0.000
M47.82 Other spondylosis (Cervical region)
0.820 0.180 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.815 0.185 0.000
J95-J99 Other diseases of the respiratory system
0.814 0.186 0.000
N17-N19 Renal failure
0.811 0.189 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.811 0.189 0.000
J84 Other interstitial pulmonary diseases
0.810 0.190 0.000
G81 Hemiplegia
0.808 0.192 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.807 0.193 0.000
I05-I09 Chronic rheumatic heart diseases
0.805 0.195 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.802 0.198 0.000
R21 Rash and other nonspecific skin eruption
0.802 0.198 0.000
J20-J22 Other acute lower respiratory infections
0.801 0.199 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.801 0.199 0.000
M48 Other spondylopathies
0.798 0.202 0.000
I67.1 Cerebral aneurysm, nonruptured
0.797 0.203 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.797 0.203 0.000
I47.1 Supraventricular tachycardia
0.794 0.206 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.793 0.207 0.000
M86-M90 Other osteopathies
0.792 0.208 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.789 0.211 0.000
I51.9 Heart disease, unspecified
0.788 0.212 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.787 0.213 0.000
I42 Cardiomyopathy
0.787 0.213 0.000
R73 Elevated blood glucose level
0.784 0.216 0.000
F30-F39 Mood [affective] disorders
0.784 0.216 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.784 0.216 0.000
F60-F69 Disorders of adult personality and behaviour
0.782 0.218 0.000
B95-B98 Bacterial, viral and other infectious agents
0.781 0.219 0.000
G20-G26 Extrapyramidal and movement disorders
0.781 0.219 0.000
I63 Cerebral infarction
0.781 0.219 0.000
J18.1 Lobar pneumonia, unspecified
0.780 0.220 0.000
N13 Obstructive and reflux uropathy
0.779 0.221 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.779 0.221 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.776 0.224 0.000
G90-G99 Other disorders of the nervous system
0.776 0.224 0.000
Chapter XXII Codes for special purposes
0.776 0.224 0.000
Y95 Nosocomial condition
0.775 0.225 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.774 0.226 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.772 0.228 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.770 0.229 0.000
J30-J39 Other diseases of upper respiratory tract
0.769 0.231 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.768 0.231 0.000
H66 Suppurative and unspecified otitis media
0.768 0.232 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.767 0.233 0.000
G81.9 Hemiplegia, unspecified
0.767 0.233 0.000
N60-N64 Disorders of breast
0.766 0.234 0.000
M54 Dorsalgia
0.763 0.237 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.762 0.238 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.762 0.238 0.000
R50 Fever of unknown origin
0.762 0.238 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.761 0.239 0.000
R56.8 Other and unspecified convulsions
0.759 0.241 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.758 0.242 0.000
S20-S29 Injuries to the thorax
0.757 0.243 0.000
M79.67 Pain in limb (Ankle and foot)
0.757 0.243 0.000
M16 Coxarthrosis [arthrosis of hip]
0.757 0.243 0.000
H60-H62 Diseases of external ear
0.755 0.245 0.000
R40 Somnolence, stupor and coma
0.754 0.246 0.000
M46 Other inflammatory spondylopathies
0.752 0.248 0.000
W00-W19 Falls
0.751 0.249 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.751 0.249 0.000
R52 Pain, not elsewhere classified
0.751 0.249 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.750 0.250 0.000
H72 Perforation of tympanic membrane
0.750 0.250 0.000
G30-G32 Other degenerative diseases of the nervous system
0.749 0.251 0.000
M65-M68 Disorders of synovium and tendon
0.749 0.251 0.000
R29.6 Tendency to fall, not elsewhere classified
0.748 0.252 0.000
O36 Maternal care for other known or suspected foetal problems
0.748 0.252 0.000
R47 Speech disturbances, not elsewhere classified
0.748 0.252 0.000
S80-S89 Injuries to the knee and lower leg
0.747 0.253 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.746 0.253 0.000
M20.1 Hallux valgus (acquired)
0.745 0.255 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.743 0.257 0.000
O48 Prolonged pregnancy
0.741 0.259 0.000
F10.2 Dependence syndrome
0.739 0.261 0.000
J93 Pneumothorax
0.739 0.261 0.000
S42 Fracture of shoulder and upper arm
0.738 0.262 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.736 0.264 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.733 0.267 0.000
N18 Chronic renal failure
0.732 0.268 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.732 0.268 0.000
E70-E90 Metabolic disorders
0.731 0.269 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.730 0.270 0.000
I60 Subarachnoid haemorrhage
0.728 0.272 0.000
S60-S69 Injuries to the wrist and hand
0.727 0.273 0.000
M20.5 Other deformities of toe(s) (acquired)
0.727 0.273 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.726 0.274 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.725 0.275 0.000
S90-S99 Injuries to the ankle and foot
0.725 0.275 0.000
N17 Acute renal failure
0.723 0.276 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.723 0.277 0.000
D60-D64 Aplastic and other anaemias
0.723 0.277 0.000
T79-T79 Certain early complications of trauma
0.720 0.279 0.000
I49.9 Cardiac arrhythmia, unspecified
0.719 0.281 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R68 Other general symptoms and signs
0.716 0.284 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.716 0.284 0.000
R62 Lack of expected normal physiological development
0.716 0.284 0.000
R57 Shock, not elsewhere classified
0.716 0.284 0.000
R64 Cachexia
0.716 0.284 0.000
R58 Haemorrhage, not elsewhere classified
0.716 0.284 0.000
R49 Voice disturbances
0.716 0.284 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.716 0.284 0.000
R22.2 Localised swelling, mass and lump, trunk
0.715 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.714 0.286 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.714 0.286 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.712 0.288 0.000
I49.3 Ventricular premature depolarisation
0.712 0.288 0.000
H93 Other disorders of ear, not elsewhere classified
0.711 0.289 0.000
R20 Disturbances of skin sensation
0.710 0.290 0.000
E20-E35 Disorders of other endocrine glands
0.710 0.290 0.000
N72 Inflammatory disease of cervix uteri
0.709 0.290 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.709 0.291 0.000
M79.7 Fibromyalgia
0.709 0.291 0.000
N13.3 Other and unspecified hydronephrosis
0.708 0.291 0.000
M21 Other acquired deformities of limbs
0.708 0.292 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.707 0.293 0.000
M77 Other enthesopathies
0.707 0.293 0.000
M15 Polyarthrosis
0.705 0.294 0.000
H71 Cholesteatoma of middle ear
0.705 0.295 0.000
I52 Other heart disorders in diseases classified elsewhere
0.704 0.296 0.000
I48 Atrial fibrillation and flutter
0.704 0.296 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.704 0.296 0.000
I41 Myocarditis in diseases classified elsewhere
0.704 0.296 0.000
I40 Acute myocarditis
0.704 0.296 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.704 0.296 0.000
I37 Pulmonary valve disorders
0.704 0.296 0.000
I36 Nonrheumatic tricuspid valve disorders
0.704 0.296 0.000
I33 Acute and subacute endocarditis
0.704 0.296 0.000
I32 Pericarditis in diseases classified elsewhere
0.704 0.296 0.000
I30 Acute pericarditis
0.704 0.296 0.000
J35 Chronic diseases of tonsils and adenoids
0.704 0.296 0.000
R41.0 Disorientation, unspecified
0.704 0.296 0.000
I51.7 Cardiomegaly
0.703 0.297 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.703 0.297 0.000
J81 Pulmonary oedema
0.702 0.297 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.702 0.297 0.000
R63.5 Abnormal weight gain
0.702 0.297 0.000
R63.3 Feeding difficulties and mismanagement
0.702 0.297 0.000
R63.2 Polyphagia
0.702 0.297 0.000
R63.1 Polydipsia
0.702 0.297 0.000
I45.9 Conduction disorder, unspecified
0.701 0.299 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.701 0.299 0.000
M19 Other arthrosis
0.699 0.301 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.698 0.301 0.000
I61 Intracerebral haemorrhage
0.698 0.302 0.000
W20-W49 Exposure to inanimate mechanical forces
0.698 0.302 0.000
H81 Disorders of vestibular function
0.698 0.302 0.000
M17.5 Other secondary gonarthrosis
0.697 0.303 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.697 0.303 0.000
M17.3 Other posttraumatic gonarthrosis
0.697 0.303 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.697 0.303 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.696 0.303 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.696 0.303 0.000
H92 Otalgia and effusion of ear
0.696 0.303 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.696 0.304 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.695 0.305 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.695 0.305 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.695 0.305 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.695 0.305 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.695 0.305 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.695 0.305 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.695 0.305 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.695 0.305 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.695 0.305 0.000
T36 Poisoning by systemic antibiotics
0.695 0.305 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.695 0.305 0.000
O60-O75 Complications of labour and delivery
0.694 0.305 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.694 0.306 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.694 0.306 0.000
I67.5 Moyamoya disease
0.694 0.306 0.000
I67.4 Hypertensive encephalopathy
0.694 0.306 0.000
I67.3 Progressive vascular leukoencephalopathy
0.694 0.306 0.000
I67.2 Cerebral atherosclerosis
0.694 0.306 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.694 0.306 0.000
I49.8 Other specified cardiac arrhythmias
0.694 0.306 0.000
N18.3 Chronic kidney disease, stage 3
0.694 0.306 0.000
M41 Scoliosis
0.693 0.307 0.000
S40 Superficial injury of shoulder and upper arm
0.692 0.308 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.691 0.309 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.691 0.309 0.000
S00-S09 Injuries to the head
0.691 0.309 0.000
F99-F99 Unspecified mental disorder
0.690 0.310 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.690 0.310 0.000
F80-F89 Disorders of psychological development
0.690 0.310 0.000
F70-F79 Mental retardation
0.690 0.310 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.690 0.310 0.000
H90.2 Conductive hearing loss, unspecified
0.687 0.312 0.000
V10-V19 Pedal cyclist injured in transport accident
0.687 0.313 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.687 0.313 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.685 0.315 0.000
J98 Other respiratory disorders
0.685 0.315 0.000
M49 Spondylopathies in diseases classified elsewhere
0.685 0.315 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.684 0.316 0.000
Y35-Y36 Legal intervention and operations of war
0.684 0.316 0.000
Y10-Y34 Event of undetermined intent
0.684 0.316 0.000
Y00-Y09 Assault
0.684 0.316 0.000
X85-X99 Assault
0.684 0.316 0.000
X60-X84 Intentional self-harm
0.684 0.316 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.684 0.316 0.000
X50-X57 Overexertion, travel and privation
0.684 0.316 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.684 0.316 0.000
X30-X39 Exposure to forces of nature
0.684 0.316 0.000
X20-X29 Contact with venomous animals and plants
0.684 0.316 0.000
X10-X19 Contact with heat and hot substances
0.684 0.316 0.000
X00-X09 Exposure to smoke, fire and flames
0.684 0.316 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.684 0.316 0.000
W75-W84 Other accidental threats to breathing
0.684 0.316 0.000
W65-W74 Accidental drowning and submersion
0.684 0.316 0.000
W50-W64 Exposure to animate mechanical forces
0.684 0.316 0.000
V98-V99 Other and unspecified transport accidents
0.684 0.316 0.000
V95-V97 Air and space transport accidents
0.684 0.316 0.000
V90-V94 Water transport accidents
0.684 0.316 0.000
V80-V89 Other land transport accidents
0.684 0.316 0.000
V70-V79 Bus occupant injured in transport accident
0.684 0.316 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.684 0.316 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.684 0.316 0.000
V40-V49 Car occupant injured in transport accident
0.684 0.316 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.684 0.316 0.000
V20-V29 Motorcycle rider injured in transport accident
0.684 0.316 0.000
V01-V09 Pedestrian injured in transport accident
0.684 0.316 0.000
T66-T78 Other and unspecified effects of external causes
0.684 0.316 0.000
M79.63 Pain in limb (Forearm)
0.684 0.316 0.000
J17 Pneumonia in diseases classified elsewhere
0.683 0.317 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.683 0.317 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.683 0.317 0.000
J12 Viral pneumonia, not elsewhere classified
0.683 0.317 0.000
J11 Influenza, virus not identified
0.683 0.317 0.000
J10 Influenza due to identified influenza virus
0.683 0.317 0.000
J14 Pneumonia due to Haemophilus influenzae
0.683 0.317 0.000
J09 Influenza due to certain identified influenza virus
0.683 0.317 0.000
M45 Ankylosing spondylitis
0.683 0.317 0.000
N00-N08 Glomerular diseases
0.682 0.318 0.000
T39.1 4-Aminophenol derivatives
0.680 0.320 0.000
R46 Symptoms and signs involving appearance and behaviour
0.680 0.320 0.000
R45 Symptoms and signs involving emotional state
0.680 0.320 0.000
R43 Disturbances of smell and taste
0.680 0.320 0.000
I42.9 Cardiomyopathy, unspecified
0.680 0.320 0.000
M18 Arthrosis of first carpometacarpal joint
0.679 0.321 0.000
G70-G73 Diseases of myoneural junction and muscle
0.678 0.322 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.678 0.322 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.678 0.322 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.678 0.322 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.678 0.322 0.000
F33 Recurrent depressive disorder
0.678 0.322 0.000
I63.8 Other cerebral infarction
0.677 0.323 0.000
M80-M85 Disorders of bone density and structure
0.676 0.324 0.000
R60 Oedema, not elsewhere classified
0.676 0.324 0.000
R23 Other skin changes
0.676 0.324 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.676 0.324 0.000
T43.2 Other and unspecified antidepressants
0.676 0.324 0.000
R27 Other lack of coordination
0.675 0.324 0.000
M79.62 Pain in limb (Upper arm)
0.675 0.325 0.000
E86 Volume depletion
0.675 0.325 0.000
G25 Other extrapyramidal and movement disorders
0.675 0.325 0.000
R79 Other abnormal findings of blood chemistry
0.673 0.327 0.000
N60 Benign mammary dysplasia
0.671 0.329 0.000
R54 Senility
0.670 0.330 0.000
I34.1 Mitral (valve) prolapse
0.670 0.330 0.000
M20.3 Other deformity of hallux (acquired)
0.668 0.332 0.000
H91.8 Other specified hearing loss
0.666 0.334 0.000
H91.3 Deaf mutism, not elsewhere classified
0.666 0.334 0.000
H91.2 Sudden idiopathic hearing loss
0.666 0.334 0.000
H91.1 Presbycusis
0.666 0.334 0.000
H91.0 Ototoxic hearing loss
0.666 0.334 0.000
I51.8 Other ill-defined heart diseases
0.666 0.334 0.000
M54.1 Radiculopathy
0.666 0.334 0.000
R25 Abnormal involuntary movements
0.665 0.335 0.000
M05-M14 Inflammatory polyarthropathies
0.665 0.335 0.000
I38 Endocarditis, valve unspecified
0.664 0.336 0.000
M20.4 Other hammer toe(s) (acquired)
0.664 0.336 0.000
R73.0 Abnormal glucose tolerance test
0.664 0.336 0.000
M24 Other specific joint derangements
0.664 0.336 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.663 0.336 0.000
J22 Unspecified acute lower respiratory infection
0.663 0.337 0.000
I05 Rheumatic mitral valve diseases
0.662 0.338 0.000
H73 Other disorders of tympanic membrane
0.662 0.338 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.662 0.338 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.661 0.339 0.000
J18.8 Other pneumonia, organism unspecified
0.661 0.339 0.000
J18.2 Hypostatic pneumonia, unspecified
0.661 0.339 0.000
N17.9 Acute renal failure, unspecified
0.661 0.339 0.000
J60-J70 Lung diseases due to external agents
0.661 0.339 0.000
J91 Pleural effusion in conditions classified elsewhere
0.660 0.340 0.000
S70-S79 Injuries to the hip and thigh
0.660 0.340 0.000
R94 Abnormal results of function studies
0.659 0.341 0.000
H65 Nonsuppurative otitis media
0.658 0.342 0.000
M25 Other joint disorders, not elsewhere classified
0.658 0.342 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.657 0.343 0.000
I69.3 Sequelae of cerebral infarction
0.657 0.343 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.657 0.343 0.000
I99 Other and unspecified disorders of circulatory system
0.657 0.343 0.000
T40.2 Other opioids
0.657 0.343 0.000
H90.3 Sensorineural hearing loss, bilateral
0.656 0.344 0.000
R22.0 Localised swelling, mass and lump, head
0.656 0.344 0.000
M79.69 Pain in limb (Site unspecified)
0.655 0.345 0.000
F00 Dementia in Alzheimer's disease
0.654 0.346 0.000
D64 Other anaemias
0.654 0.346 0.000
T39.0 Salicylates
0.653 0.347 0.000
F10.1 Harmful use
0.653 0.347 0.000
I10-I15 Hypertensive diseases
0.652 0.348 0.000
F60 Specific personality disorders
0.652 0.348 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.652 0.348 0.000
M43 Other deforming dorsopathies
0.651 0.348 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.651 0.349 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.651 0.349 0.000
O36.9 Maternal care for foetal problem, unspecified
0.651 0.349 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.650 0.349 0.000
H74 Other disorders of middle ear and mastoid
0.650 0.349 0.000
H70 Mastoiditis and related conditions
0.650 0.349 0.000
H69 Other disorders of Eustachian tube
0.650 0.349 0.000
H68 Eustachian salpingitis and obstruction
0.650 0.349 0.000
H67 Otitis media in diseases classified elsewhere
0.650 0.349 0.000
R52.9 Pain, unspecified
0.650 0.350 0.000
S50-S59 Injuries to the elbow and forearm
0.650 0.350 0.000
I45.1 Other and unspecified right bundle-branch block
0.649 0.351 0.000
R55 Syncope and collapse
0.649 0.351 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.648 0.352 0.000
I65.2 Occlusion and stenosis of carotid artery
0.648 0.352 0.000
M79.60 Pain in limb (Multiple sites)
0.648 0.352 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.647 0.353 0.000
M34 Systemic sclerosis
0.647 0.353 0.000
M33 Dermatopolymyositis
0.647 0.353 0.000
M32 Systemic lupus erythematosus
0.647 0.353 0.000
M30 Polyarteritis nodosa and related conditions
0.647 0.353 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.647 0.353 0.000
R73.9 Hyperglycaemia, unspecified
0.647 0.353 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.647 0.353 0.000
Chapter VII Diseases of the eye and adnexa
0.647 0.353 0.000
M48.0 Spinal stenosis
0.646 0.354 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.644 0.356 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.644 0.356 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.644 0.356 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.644 0.356 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.644 0.356 0.000
J80 Adult respiratory distress syndrome
0.644 0.356 0.000
B25-B34 Other viral diseases
0.644 0.356 0.000
M54.5 Low back pain
0.643 0.357 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.643 0.357 0.000
I31 Other diseases of pericardium
0.643 0.357 0.000
M76 Enthesopathies of lower limb, excluding foot
0.642 0.358 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.642 0.358 0.000
M71 Other bursopathies
0.642 0.358 0.000
M20.2 Hallux rigidus
0.641 0.359 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.640 0.359 0.000
F10.3 Withdrawal state
0.640 0.360 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.639 0.361 0.000
S48 Traumatic amputation of shoulder and upper arm
0.639 0.361 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.639 0.361 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.639 0.361 0.000
S44 Injury of nerves at shoulder and upper arm level
0.639 0.361 0.000
S41 Open wound of shoulder and upper arm
0.639 0.361 0.000
S47 Crushing injury of shoulder and upper arm
0.639 0.361 0.000
T81 Complications of procedures, not elsewhere classified
0.639 0.361 0.000
I51.6 Cardiovascular disease, unspecified
0.638 0.362 0.000
I51.5 Myocardial degeneration
0.638 0.362 0.000
I51.4 Myocarditis, unspecified
0.638 0.362 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.638 0.362 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.638 0.362 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.638 0.362 0.000
I51.0 Cardiac septal defect, acquired
0.638 0.362 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.638 0.362 0.000
O85-O92 Complications predominantly related to the puerperium
0.637 0.363 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.637 0.363 0.000
R77 Other abnormalities of plasma proteins
0.637 0.363 0.000
R76 Other abnormal immunological findings in serum
0.637 0.363 0.000
R74 Abnormal serum enzyme levels
0.637 0.363 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.637 0.363 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.637 0.363 0.000
R71 Abnormality of red blood cells
0.637 0.363 0.000
M79.8 Other specified soft tissue disorders
0.636 0.364 0.000
H66.9 Otitis media, unspecified
0.636 0.364 0.000
T87 Complications peculiar to reattachment and amputation
0.635 0.365 0.000
T86 Failure and rejection of transplanted organs and tissues
0.635 0.365 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.635 0.365 0.000
I44 Atrioventricular and left bundle-branch block
0.635 0.365 0.000
G40-G47 Episodic and paroxysmal disorders
0.634 0.366 0.000
M47.2 Other spondylosis with radiculopathy
0.632 0.368 0.000
M47.1 Other spondylosis with myelopathy
0.632 0.368 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.632 0.368 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.632 0.368 0.000
I49.0 Ventricular fibrillation and flutter
0.632 0.368 0.000
M53 Other dorsopathies, not elsewhere classified
0.632 0.368 0.000
R61 Hyperhidrosis
0.631 0.368 0.000
I46 Cardiac arrest
0.631 0.369 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.631 0.369 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.631 0.369 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.631 0.369 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.631 0.369 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.631 0.369 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.631 0.369 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.631 0.369 0.000
F11 Mental and behavioural disorders due to use of opioids
0.631 0.369 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.631 0.369 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.630 0.369 0.000
T17 Foreign body in respiratory tract
0.630 0.370 0.000
I73 Other peripheral vascular diseases
0.630 0.370 0.000
M86 Osteomyelitis
0.629 0.371 0.000
B15-B19 Viral hepatitis
0.628 0.372 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.627 0.373 0.000
B35-B49 Mycoses
0.627 0.373 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.627 0.373 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.627 0.373 0.000
T39.4 Antirheumatics, not elsewhere classified
0.627 0.373 0.000
T39.2 Pyrazolone derivatives
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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