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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2293861
log Bayes Factor = 22.1695
Chromosome 6   position 31,711,124  (GRCh37) Explore rs2293861 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.036 0.964
D69.6 Thrombocytopenia, unspecified
0.000 0.407 0.593
D69 Purpura and other haemorrhagic conditions
0.000 0.411 0.589
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.415 0.585
K90 Intestinal malabsorption
0.000 0.503 0.496
D69.5 Secondary thrombocytopenia
0.000 0.547 0.453
D69.9 Haemorrhagic condition, unspecified
0.000 0.560 0.440
D69.0 Allergic purpura
0.000 0.561 0.439
D69.8 Other specified haemorrhagic conditions
0.000 0.578 0.422
D69.2 Other nonthrombocytopenic purpura
0.000 0.578 0.422
D69.1 Qualitative platelet defects
0.000 0.578 0.422
E03 Other hypothyroidism
0.000 0.592 0.408
D69.4 Other primary thrombocytopenia
0.000 0.592 0.407
K90.9 Intestinal malabsorption, unspecified
0.000 0.596 0.404
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.598 0.402
D86 Sarcoidosis
0.000 0.617 0.383
D80-D89 Certain disorders involving the immune mechanism
0.000 0.619 0.381
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.625 0.375
D86.9 Sarcoidosis, unspecified
0.000 0.627 0.373
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.632 0.368
D86.0 Sarcoidosis of lung
0.000 0.643 0.357
K90.3 Pancreatic steatorrhoea
0.000 0.644 0.356
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.644 0.356
K90.1 Tropical sprue
0.000 0.644 0.356
D80 Immunodeficiency with predominantly antibody defects
0.000 0.659 0.341
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.688 0.312
K90.8 Other intestinal malabsorption
0.000 0.693 0.307
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.696 0.304
D84 Other immunodeficiencies
0.000 0.701 0.299
D86.1 Sarcoidosis of lymph nodes
0.000 0.705 0.295
E03.5 Myxoedema coma
0.000 0.707 0.293
E03.4 Atrophy of thyroid (acquired)
0.000 0.707 0.293
E03.3 Postinfectious hypothyroidism
0.000 0.707 0.293
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.707 0.293
E03.1 Congenital hypothyroidism without goitre
0.000 0.707 0.293
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.707 0.293
D73 Diseases of spleen
0.000 0.709 0.291
E03.8 Other specified hypothyroidism
0.000 0.711 0.289
D67 Hereditary factor IX deficiency
0.000 0.711 0.288
D86.8 Sarcoidosis of other and combined sites
0.000 0.712 0.288
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.718 0.282
D73.0 Hyposplenism
0.000 0.720 0.280
D86.3 Sarcoidosis of skin
0.000 0.725 0.275
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.725 0.275
D83 Common variable immunodeficiency
0.000 0.726 0.274
D82 Immunodeficiency associated with other major defects
0.000 0.726 0.274
D81 Combined immunodeficiencies
0.000 0.726 0.274
D66 Hereditary factor VIII deficiency
0.000 0.753 0.247
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.755 0.244
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.755 0.244
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.755 0.244
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.755 0.244
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.755 0.244
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.755 0.244
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.755 0.244
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.755 0.244
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.755 0.244
D55-D59 Haemolytic anaemias
0.000 0.760 0.240
D84.9 Immunodeficiency, unspecified
0.000 0.760 0.240
D73.5 Infarction of spleen
0.000 0.765 0.234
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.769 0.230
D72 Other disorders of white blood cells
0.000 0.780 0.220
D74 Methaemoglobinaemia
0.000 0.782 0.218
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.782 0.218
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.782 0.218
D84.8 Other specified immunodeficiencies
0.000 0.785 0.214
D84.1 Defects in the complement system
0.000 0.785 0.214
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.785 0.214
D73.9 Disease of spleen, unspecified
0.000 0.791 0.209
D73.8 Other diseases of spleen
0.000 0.791 0.209
D73.3 Abscess of spleen
0.000 0.791 0.209
D73.2 Chronic congestive splenomegaly
0.000 0.791 0.209
D73.1 Hypersplenism
0.000 0.791 0.209
D81.9 Combined immunodeficiency, unspecified
0.000 0.804 0.196
D81.8 Other combined immunodeficiencies
0.000 0.804 0.196
D81.7 Major histocompatibility complex class II deficiency
0.000 0.804 0.196
D81.6 Major histocompatibility complex class I deficiency
0.000 0.804 0.196
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.804 0.196
D81.4 Nezelof's syndrome
0.000 0.804 0.196
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.804 0.196
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.804 0.196
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.804 0.196
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.804 0.196
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.804 0.196
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.804 0.196
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.804 0.196
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.804 0.196
D82.2 Immunodeficiency with short-limbed stature
0.000 0.804 0.196
D82.1 Di George's syndrome
0.000 0.804 0.196
D82.0 Wiskott-Aldrich syndrome
0.000 0.804 0.196
D83.9 Common variable immunodeficiency, unspecified
0.000 0.804 0.196
D83.8 Other common variable immunodeficiencies
0.000 0.804 0.196
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.804 0.196
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.804 0.196
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.804 0.196
D73.4 Cyst of spleen
0.000 0.804 0.196
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.805 0.195
D59 Acquired haemolytic anaemia
0.000 0.807 0.193
D50-D53 Nutritional anaemias
0.000 0.824 0.176
D57 Sickle-cell disorders
0.000 0.828 0.172
D55 Anaemia due to enzyme disorders
0.000 0.828 0.172
D70 Agranulocytosis
0.000 0.829 0.171
D59.1 Other autoimmune haemolytic anaemias
0.000 0.834 0.165
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.834 0.165
D89.3 Immune reconstitution syndrome
0.000 0.834 0.165
D89.1 Cryoglobulinaemia
0.000 0.834 0.165
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.834 0.165
D72.8 Other specified disorders of white blood cells
0.000 0.837 0.163
D56 Thalassaemia
0.000 0.837 0.163
D72.9 Disorder of white blood cells, unspecified
0.000 0.842 0.158
D72.0 Genetic anomalies of leukocytes
0.000 0.842 0.158
D74.9 Methaemoglobinaemia, unspecified
0.000 0.843 0.156
D74.8 Other methaemoglobinaemias
0.000 0.843 0.156
D74.0 Congenital methaemoglobinaemia
0.000 0.843 0.156
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.846 0.154
D72.1 Eosinophilia
0.000 0.847 0.153
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.850 0.150
D60-D64 Aplastic and other anaemias
0.000 0.860 0.140
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.860 0.140
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.860 0.140
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.860 0.140
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.861 0.139
D59.8 Other acquired haemolytic anaemias
0.000 0.861 0.138
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.861 0.138
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.861 0.138
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.861 0.138
D59.3 Haemolytic-uraemic syndrome
0.000 0.861 0.138
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.861 0.138
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.861 0.138
D75 Other diseases of blood and blood-forming organs
0.000 0.862 0.137
D53 Other nutritional anaemias
0.000 0.864 0.135
D52 Folate deficiency anaemia
0.000 0.869 0.130
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.873 0.127
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.876 0.124
D55.8 Other anaemias due to enzyme disorders
0.000 0.876 0.124
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.876 0.124
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.876 0.124
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.876 0.124
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.876 0.124
D57.8 Other sickle-cell disorders
0.000 0.876 0.124
D57.3 Sickle-cell trait
0.000 0.876 0.124
D57.2 Double heterozygous sickling disorders
0.000 0.876 0.124
D57.1 Sickle-cell anaemia without crisis
0.000 0.876 0.124
D57.0 Sickle-cell anaemia with crisis
0.000 0.876 0.124
E10 Insulin-dependent diabetes mellitus
0.123 0.877 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.879 0.120
E10.4 With neurological complications
0.119 0.881 0.000
D58 Other hereditary haemolytic anaemias
0.001 0.882 0.117
D56.9 Thalassaemia, unspecified
0.000 0.883 0.117
D56.8 Other thalassaemias
0.000 0.883 0.117
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.883 0.117
D56.2 Delta-beta thalassaemia
0.000 0.883 0.117
D56.1 Beta thalassaemia
0.000 0.883 0.117
D56.0 Alpha thalassaemia
0.000 0.883 0.117
D76.3 Other histiocytosis syndromes
0.000 0.883 0.117
E10.2 With renal complications
0.113 0.887 0.000
E10.3 With ophthalmic complications
0.111 0.889 0.000
D62 Acute posthaemorrhagic anaemia
0.000 0.889 0.111
D56.3 Thalassaemia trait
0.000 0.892 0.107
D53.9 Nutritional anaemia, unspecified
0.000 0.894 0.106
E10.9 Without complications
0.106 0.894 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.895 0.105
E10.0 With coma
0.103 0.897 0.000
D75.2 Essential thrombocytosis
0.000 0.899 0.101
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.899 0.101
E10.5 With peripheral circulatory complications
0.100 0.900 0.000
D52.9 Folate deficiency anaemia, unspecified
0.000 0.902 0.098
E10.1 With ketoacidosis
0.097 0.902 0.000
D53.8 Other specified nutritional anaemias
0.000 0.903 0.097
D53.2 Scorbutic anaemia
0.000 0.903 0.097
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.903 0.097
D53.0 Protein deficiency anaemia
0.000 0.903 0.097
E10.6 With other specified complications
0.096 0.904 0.000
D52.8 Other folate deficiency anaemias
0.000 0.906 0.094
D52.1 Drug-induced folate deficiency anaemia
0.000 0.906 0.094
D52.0 Dietary folate deficiency anaemia
0.000 0.906 0.094
E10.7 With multiple complications
0.088 0.912 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.001 0.915 0.084
D58.2 Other haemoglobinopathies
0.001 0.915 0.084
D58.1 Hereditary elliptocytosis
0.001 0.915 0.084
M45.X9 Ankylosing spondylitis (Site unspecified)
0.085 0.915 0.000
E10.8 With unspecified complications
0.083 0.916 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.920 0.080
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.920 0.079
D75.0 Familial erythrocytosis
0.001 0.924 0.076
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.924 0.076
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.924 0.076
D51.2 Transcobalamin II deficiency
0.000 0.924 0.076
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.924 0.076
M45 Ankylosing spondylitis
0.074 0.926 0.000
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.928 0.072
D60.8 Other acquired pure red cell aplasias
0.000 0.928 0.072
D60.1 Transient acquired pure red cell aplasia
0.000 0.928 0.072
D60.0 Chronic acquired pure red cell aplasia
0.000 0.928 0.072
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.069 0.931 0.000
G35 Multiple sclerosis
0.000 0.932 0.068
D64 Other anaemias
0.000 0.933 0.067
D58.0 Hereditary spherocytosis
0.001 0.934 0.065
D58.9 Hereditary haemolytic anaemia, unspecified
0.001 0.938 0.061
D61 Other aplastic anaemias
0.000 0.939 0.060
D63.0 Anaemia in neoplastic disease
0.000 0.940 0.060
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.060 0.940 0.000
M06.9 Rheumatoid arthritis, unspecified
0.058 0.942 0.000
M06 Other rheumatoid arthritis
0.057 0.943 0.000
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.943 0.057
E10-E14 Diabetes mellitus
0.057 0.943 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.057 0.943 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.001 0.945 0.054
K90-K93 Other diseases of the digestive system
0.001 0.946 0.053
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.053 0.947 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.053 0.947 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.053 0.947 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.053 0.947 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.053 0.947 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.053 0.947 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.053 0.947 0.000
D75.1 Secondary polycythaemia
0.000 0.947 0.052
M05-M14 Inflammatory polyarthropathies
0.051 0.949 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.050 0.950 0.000
M06.0 Seronegative rheumatoid arthritis
0.050 0.950 0.000
D64.8 Other specified anaemias
0.000 0.951 0.049
M07 Psoriatic and enteropathic arthropathies
0.048 0.951 0.000
D64.4 Congenital dyserythropoietic anaemia
0.000 0.952 0.048
D64.3 Other sideroblastic anaemias
0.000 0.952 0.048
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.952 0.048
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.952 0.048
D64.0 Hereditary sideroblastic anaemia
0.000 0.952 0.048
M06.3 Rheumatoid nodule
0.047 0.952 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.047 0.953 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.953 0.047
M07.3 Other psoriatic arthropathies
0.047 0.953 0.000
M06.4 Inflammatory polyarthropathy
0.045 0.955 0.000
D61.8 Other specified aplastic anaemias
0.000 0.956 0.043
D61.3 Idiopathic aplastic anaemia
0.000 0.956 0.043
D61.2 Aplastic anaemia due to other external agents
0.000 0.956 0.043
D61.0 Constitutional aplastic anaemia
0.000 0.956 0.043
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.044 0.956 0.000
E14 Unspecified diabetes mellitus
0.043 0.957 0.000
E13 Other specified diabetes mellitus
0.043 0.957 0.000
M14 Arthropathies in other diseases classified elsewhere
0.043 0.957 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.042 0.958 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.042 0.958 0.000
D50 Iron deficiency anaemia
0.000 0.958 0.042
M06.8 Other specified rheumatoid arthritis
0.041 0.959 0.000
M06.2 Rheumatoid bursitis
0.041 0.959 0.000
M06.1 Adult-onset Still's disease
0.041 0.959 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.041 0.959 0.000
E12 Malnutrition-related diabetes mellitus
0.041 0.959 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.041 0.959 0.000
M11 Other crystal arthropathies
0.041 0.959 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.040 0.960 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.040 0.960 0.000
D61.1 Drug-induced aplastic anaemia
0.000 0.961 0.039
M45-M49 Spondylopathies
0.039 0.961 0.000
E11 Non-insulin-dependent diabetes mellitus
0.039 0.961 0.000
Q61 Cystic kidney disease
0.039 0.961 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.039 0.961 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.001 0.961 0.038
M06.34 Rheumatoid nodule (Hand)
0.039 0.961 0.000
E11.4 With neurological complications
0.038 0.962 0.000
E14.8 With unspecified complications
0.038 0.962 0.000
Q61.0 Congenital single renal cyst
0.038 0.962 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.037 0.963 0.000
M12 Other specific arthropathies
0.037 0.963 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.037 0.963 0.000
M08 Juvenile arthritis
0.037 0.963 0.000
M05 Seropositive rheumatoid arthritis
0.037 0.963 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.037 0.963 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.037 0.963 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.036 0.963 0.000
E14.6 With other specified complications
0.036 0.963 0.000
M14.6 Neuropathic arthropathy
0.036 0.963 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.036 0.964 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.036 0.964 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.036 0.964 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.036 0.964 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.036 0.964 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.036 0.964 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.036 0.964 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.036 0.964 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.036 0.964 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.036 0.964 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.036 0.964 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.036 0.964 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.035 0.965 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.035 0.965 0.000
E11.0 With coma
0.035 0.965 0.000
M07.6 Other enteropathic arthropathies
0.035 0.965 0.000
M07.5 Arthropathy in ulcerative colitis
0.035 0.965 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.035 0.965 0.000
M07.2 Psoriatic spondylitis
0.035 0.965 0.000
M07.1 Arthritis mutilans
0.035 0.965 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.035 0.965 0.000
Q61.3 Polycystic kidney, unspecified
0.035 0.965 0.000
E14.5 With peripheral circulatory complications
0.035 0.965 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.034 0.966 0.000
M06.38 Rheumatoid nodule (Other)
0.034 0.966 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.034 0.966 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.034 0.966 0.000
M06.33 Rheumatoid nodule (Forearm)
0.034 0.966 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.034 0.966 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.034 0.966 0.000
E14.4 With neurological complications
0.034 0.966 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.034 0.966 0.000
M07.38 Other psoriatic arthropathies (Other)
0.034 0.966 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.034 0.966 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.034 0.966 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.034 0.966 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.034 0.966 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.034 0.966 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.034 0.966 0.000
Q60-Q64 Congenital malformations of the urinary system
0.033 0.967 0.000
E13.9 Without complications
0.033 0.967 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.033 0.967 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.033 0.967 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.033 0.967 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.033 0.967 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.033 0.967 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.033 0.967 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.033 0.967 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.033 0.967 0.000
Q61.2 Polycystic kidney, adult type
0.032 0.968 0.000
M67 Other disorders of synovium and tendon
0.032 0.968 0.000
M65-M68 Disorders of synovium and tendon
0.032 0.968 0.000
M11.9 Crystal arthropathy, unspecified
0.032 0.968 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.032 0.968 0.000
Q61.4 Renal dysplasia
0.032 0.968 0.000
M49 Spondylopathies in diseases classified elsewhere
0.031 0.969 0.000
E14.1 With ketoacidosis
0.031 0.969 0.000
E14.7 With multiple complications
0.031 0.969 0.000
E14.2 Withrenal complications
0.031 0.969 0.000
E14.0 With coma
0.031 0.969 0.000
E13.8 With unspecified complications
0.031 0.969 0.000
E13.7 With multiple complications
0.031 0.969 0.000
E13.6 With other specified complications
0.031 0.969 0.000
E13.5 With peripheral circulatory complications
0.031 0.969 0.000
E13.4 With neurological complications
0.031 0.969 0.000
E13.3 With ophthalmic complications
0.031 0.969 0.000
E13.2 With renal complications
0.031 0.969 0.000
E13.1 With ketoacidosis
0.031 0.969 0.000
E13.0 With coma
0.031 0.969 0.000
Q61.5 Medullary cystic kidney
0.031 0.969 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.031 0.969 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.031 0.969 0.000
M14.4 Arthropathy in amyloidosis
0.031 0.969 0.000
M14.3 Lipoid dermatoarthritis
0.031 0.969 0.000
M14.2 Diabetic arthropathy
0.031 0.969 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.031 0.969 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.031 0.969 0.000
M11.2 Other chondrocalcinosis
0.031 0.969 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.030 0.969 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.030 0.970 0.000
M00-M03 Infectious arthropathies
0.030 0.970 0.000
D50.1 Sideropenic dysphagia
0.000 0.970 0.030
M67.8 Other specified disorders of synovium and tendon
0.030 0.970 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.030 0.970 0.000
M06.18 Adult-onset Still's disease (Other)
0.030 0.970 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.030 0.970 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.030 0.970 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.030 0.970 0.000
M06.14 Adult-onset Still's disease (Hand)
0.030 0.970 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.030 0.970 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.030 0.970 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.030 0.970 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.030 0.970 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.030 0.970 0.000
M06.28 Rheumatoid bursitis (Other)
0.030 0.970 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.030 0.970 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.030 0.970 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.030 0.970 0.000
M06.24 Rheumatoid bursitis (Hand)
0.030 0.970 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.030 0.970 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.030 0.970 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.030 0.970 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.030 0.970 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.030 0.970 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.030 0.970 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.030 0.970 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.030 0.970 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.030 0.970 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.030 0.970 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.030 0.970 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.030 0.970 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.030 0.970 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.030 0.970 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.970 0.030
E12.9 Without complications
0.029 0.970 0.000
E12.8 With unspecified complications
0.029 0.970 0.000
E12.7 With multiple complications
0.029 0.970 0.000
E12.6 With other specified complications
0.029 0.970 0.000
E12.5 With peripheral circulatory complications
0.029 0.970 0.000
E12.4 With neurological complications
0.029 0.970 0.000
E12.3 With ophthalmic complications
0.029 0.970 0.000
E12.2 With renal complications
0.029 0.970 0.000
E12.1 With ketoacidosis
0.029 0.970 0.000
E12.0 With coma
0.029 0.970 0.000
M60-M63 Disorders of muscles
0.030 0.970 0.000
M11.8 Other specified crystal arthropathies
0.029 0.971 0.000
M11.1 Familial chondrocalcinosis
0.029 0.971 0.000
M11.0 Hydroxyapatite deposition disease
0.029 0.971 0.000
M67.1 Other contracture of tendon (sheath)
0.029 0.971 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.028 0.972 0.000
E11.5 With peripheral circulatory complications
0.028 0.972 0.000
M91-M94 Chondropathies
0.028 0.972 0.000
E11.7 With multiple complications
0.028 0.972 0.000
Q61.9 Cystic kidney disease, unspecified
0.028 0.972 0.000
Q61.8 Other cystic kidney diseases
0.028 0.972 0.000
Q61.1 Polycystic kidney, infantile type
0.028 0.972 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.001 0.972 0.027
K93.1 Megacolon in Chagas' disease
0.001 0.972 0.027
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.001 0.972 0.027
E11.1 With ketoacidosis
0.027 0.972 0.000
M80-M85 Disorders of bone density and structure
0.027 0.973 0.000
D68 Other coagulation defects
0.001 0.973 0.026
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.973 0.027
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.027 0.973 0.000
M10 Gout
0.027 0.973 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.027 0.973 0.000
M08.9 Juvenile arthritis, unspecified
0.027 0.973 0.000
M08.8 Other juvenile arthritis
0.027 0.973 0.000
M08.4 Pauciarticular juvenile arthritis
0.027 0.973 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.027 0.973 0.000
M08.2 Juvenile arthritis with systemic onset
0.027 0.973 0.000
M08.1 Juvenile ankylosing spondylitis
0.027 0.973 0.000
M08.0 Juvenile rheumatoid arthritis
0.027 0.973 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.027 0.973 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.027 0.973 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.027 0.973 0.000
M09.0 Juvenile arthritis in psoriasis
0.027 0.973 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.027 0.973 0.000
M12.5 Traumatic arthropathy
0.027 0.973 0.000
M12.4 Intermittent hydrarthrosis
0.027 0.973 0.000
M12.3 Palindromic rheumatism
0.027 0.973 0.000
M12.2 Villonodular synovitis (pigmented)
0.027 0.973 0.000
M12.1 Kaschin-Beck disease
0.027 0.973 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.027 0.973 0.000
M05.8 Other seropositive rheumatoid arthritis
0.026 0.973 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.026 0.973 0.000
M05.2 Rheumatoid vasculitis
0.026 0.973 0.000
M05.1 Rheumatoid lung disease
0.026 0.973 0.000
M05.0 Felty's syndrome
0.026 0.973 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.026 0.973 0.000
M95.0 Acquired deformity of nose
0.026 0.974 0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)
0.026 0.974 0.000
E11.6 With other specified complications
0.026 0.974 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.974 0.026
Q64 Other congenital malformations of urinary system
0.026 0.974 0.000
Q38.7 Pharyngeal pouch
0.026 0.974 0.000
M99 Biomechanical lesions, not elsewhere classified
0.026 0.974 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.026 0.974 0.000
I83 Varicose veins of lower extremities
0.000 0.974 0.026
K92.1 Melaena
0.000 0.974 0.026
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.025 0.975 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.025 0.975 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.025 0.975 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.025 0.975 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.025 0.975 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.025 0.975 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.025 0.975 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.025 0.975 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.025 0.975 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.025 0.975 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.025 0.975 0.000
M07.18 Arthritis mutilans (Other)
0.025 0.975 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.025 0.975 0.000
M07.16 Arthritis mutilans (Lower leg)
0.025 0.975 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.025 0.975 0.000
M07.14 Arthritis mutilans (Hand)
0.025 0.975 0.000
M07.13 Arthritis mutilans (Forearm)
0.025 0.975 0.000
M07.12 Arthritis mutilans (Upper arm)
0.025 0.975 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.025 0.975 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.025 0.975 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.025 0.975 0.000
M07.28 Psoriatic spondylitis (Other)
0.025 0.975 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.025 0.975 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.025 0.975 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.025 0.975 0.000
M07.24 Psoriatic spondylitis (Hand)
0.025 0.975 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.025 0.975 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.025 0.975 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.025 0.975 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.025 0.975 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.025 0.975 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.025 0.975 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.025 0.975 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.025 0.975 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.025 0.975 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.025 0.975 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.025 0.975 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.025 0.975 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.025 0.975 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.025 0.975 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.025 0.975 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.025 0.975 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.025 0.975 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.025 0.975 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.025 0.975 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.025 0.975 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.025 0.975 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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