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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2294309
log Bayes Factor = 29.6881
Chromosome 6   position 27,483,816  (GRCh37) Explore rs2294309 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.608 0.392
E10.9 Without complications
0.000 0.615 0.385
E83 Disorders of mineral metabolism
0.000 0.631 0.369
E10.3 With ophthalmic complications
0.000 0.651 0.349
E10.5 With peripheral circulatory complications
0.000 0.653 0.347
E10-E14 Diabetes mellitus
0.000 0.653 0.347
E10.8 With unspecified complications
0.000 0.659 0.341
E10.1 With ketoacidosis
0.000 0.662 0.338
E70-E90 Metabolic disorders
0.000 0.668 0.332
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.672 0.328
E88 Other metabolic disorders
0.000 0.677 0.323
E10.4 With neurological complications
0.000 0.687 0.313
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.693 0.307
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.693 0.307
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.700 0.300
E16 Other disorders of pancreatic internal secretion
0.000 0.708 0.292
E80.4 Gilbert's syndrome
0.000 0.712 0.288
E10.7 With multiple complications
0.000 0.714 0.286
E13 Other specified diabetes mellitus
0.000 0.714 0.286
E10.0 With coma
0.000 0.715 0.284
E10.6 With other specified complications
0.000 0.716 0.284
E16.2 Hypoglycaemia, unspecified
0.000 0.720 0.280
E27.1 Primary adrenocortical insufficiency
0.000 0.730 0.270
E84 Cystic fibrosis
0.000 0.734 0.265
E88.8 Other specified metabolic disorders
0.000 0.734 0.265
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.736 0.264
E83.8 Other disorders of mineral metabolism
0.000 0.736 0.264
E83.2 Disorders of zinc metabolism
0.000 0.736 0.264
E83.0 Disorders of copper metabolism
0.000 0.736 0.264
E20-E35 Disorders of other endocrine glands
0.000 0.738 0.262
E10.2 With renal complications
0.000 0.739 0.260
E27 Other disorders of adrenal gland
0.000 0.740 0.260
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.743 0.257
E88.3 Tumour lysis syndrome
0.000 0.750 0.250
E12 Malnutrition-related diabetes mellitus
0.000 0.751 0.249
E88.2 Lipomatosis, not elsewhere classified
0.000 0.752 0.248
E40-E46 Malnutrition
0.000 0.753 0.247
E13.9 Without complications
0.000 0.759 0.241
E77 Disorders of glycoprotein metabolism
0.000 0.762 0.238
E76 Disorders of glycosaminoglycan metabolism
0.000 0.762 0.238
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.762 0.238
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.762 0.238
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.765 0.235
E70 Disorders of aromatic amino-acid metabolism
0.000 0.765 0.235
E72 Other disorders of amino-acid metabolism
0.000 0.767 0.233
E80.6 Other disorders of bilirubin metabolism
0.000 0.771 0.229
E88.9 Metabolic disorder, unspecified
0.000 0.771 0.229
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.773 0.227
E20 Hypoparathyroidism
0.000 0.775 0.225
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.780 0.220
E80.5 Crigler-Najjar syndrome
0.000 0.780 0.220
E80.3 Defects of catalase and peroxydase
0.000 0.780 0.220
E80.1 Porphyria cutanea tarda
0.000 0.780 0.220
E80.0 Hereditary erythropoietic porphyria
0.000 0.780 0.220
E15 Nondiabetic hypoglycaemic coma
0.000 0.780 0.220
E14 Unspecified diabetes mellitus
0.000 0.781 0.219
E84.9 Cystic fibrosis, unspecified
0.000 0.782 0.218
E29 Testicular dysfunction
0.000 0.782 0.217
K90 Intestinal malabsorption
0.000 0.785 0.215
E80.2 Other porphyria
0.000 0.786 0.214
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.791 0.209
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.791 0.209
E16.4 Abnormal secretion of gastrin
0.000 0.791 0.209
E16.3 Increased secretion of glucagon
0.000 0.791 0.209
E13.3 With ophthalmic complications
0.000 0.793 0.207
E79 Disorders of purine and pyrimidine metabolism
0.000 0.793 0.207
E14.3 With ophthalmic complications
0.000 0.793 0.207
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.794 0.206
E13.8 With unspecified complications
0.000 0.795 0.205
E13.7 With multiple complications
0.000 0.795 0.205
E13.6 With other specified complications
0.000 0.795 0.205
E13.5 With peripheral circulatory complications
0.000 0.795 0.205
E13.4 With neurological complications
0.000 0.795 0.205
E13.2 With renal complications
0.000 0.795 0.205
E13.1 With ketoacidosis
0.000 0.795 0.205
E13.0 With coma
0.000 0.795 0.205
E24 Cushing's syndrome
0.000 0.797 0.203
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.798 0.202
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.799 0.201
E20.9 Hypoparathyroidism, unspecified
0.000 0.802 0.198
E26 Hyperaldosteronism
0.000 0.807 0.193
E74 Other disorders of carbohydrate metabolism
0.000 0.809 0.191
E84.8 Cystic fibrosis with other manifestations
0.000 0.809 0.190
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.809 0.190
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.809 0.190
E46 Unspecified protein-energy malnutrition
0.000 0.812 0.188
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.812 0.188
E32 Diseases of thymus
0.000 0.812 0.188
E31 Polyglandular dysfunction
0.000 0.812 0.188
E30 Disorders of puberty, not elsewhere classified
0.000 0.812 0.188
E25 Adrenogenital disorders
0.000 0.812 0.188
E73 Lactose intolerance
0.000 0.813 0.187
E27.5 Adrenomedullary hyperfunction
0.000 0.814 0.186
E27.0 Other adrenocortical overactivity
0.000 0.814 0.186
E29.1 Testicular hypofunction
0.000 0.814 0.186
E65-E68 Obesity and other hyperalimentation
0.000 0.817 0.183
E12.9 Without complications
0.000 0.821 0.179
E12.8 With unspecified complications
0.000 0.821 0.179
E12.7 With multiple complications
0.000 0.821 0.179
E12.6 With other specified complications
0.000 0.821 0.179
E12.5 With peripheral circulatory complications
0.000 0.821 0.179
E12.4 With neurological complications
0.000 0.821 0.179
E12.3 With ophthalmic complications
0.000 0.821 0.179
E12.2 With renal complications
0.000 0.821 0.179
E12.1 With ketoacidosis
0.000 0.821 0.179
E12.0 With coma
0.000 0.821 0.179
E24.2 Drug-induced Cushing's syndrome
0.000 0.822 0.178
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.822 0.178
E16.1 Other hypoglycaemia
0.000 0.822 0.177
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.823 0.177
E45 Retarded development following protein-energy malnutrition
0.000 0.823 0.177
E43 Unspecified severe protein-energy malnutrition
0.000 0.823 0.177
E42 Marasmic kwashiorkor
0.000 0.823 0.177
E41 Nutritional marasmus
0.000 0.823 0.177
E40 Kwashiorkor
0.000 0.823 0.177
E14.5 With peripheral circulatory complications
0.000 0.829 0.171
E71.3 Disorders of fatty-acid metabolism
0.000 0.829 0.171
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.829 0.171
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.829 0.171
E71.0 Maple-syrup-urine disease
0.000 0.829 0.171
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.829 0.171
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.829 0.171
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.829 0.171
E76.2 Other mucopolysaccharidoses
0.000 0.829 0.171
E76.1 Mucopolysaccharidosis, type II
0.000 0.829 0.171
E76.0 Mucopolysaccharidosis, type I
0.000 0.829 0.171
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.829 0.171
E77.8 Other disorders of glycoprotein metabolism
0.000 0.829 0.171
E77.1 Defects in glycoprotein degradation
0.000 0.829 0.171
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.829 0.171
E83.3 Disorders of phosphorus metabolism
0.000 0.831 0.169
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.832 0.168
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.832 0.168
E70.2 Disorders of tyrosine metabolism
0.000 0.832 0.168
E70.1 Other hyperphenylalaninaemias
0.000 0.832 0.168
E70.0 Classical phenylketonuria
0.000 0.832 0.168
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.833 0.167
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.833 0.167
E72.5 Disorders of glycine metabolism
0.000 0.833 0.167
E72.4 Disorders of ornithine metabolism
0.000 0.833 0.167
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.833 0.167
E72.2 Disorders of urea cycle metabolism
0.000 0.833 0.167
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.833 0.167
E27.2 Addisonian crisis
0.000 0.833 0.167
E70.3 Albinism
0.000 0.835 0.165
E14.2 Withrenal complications
0.000 0.837 0.163
E75.6 Lipid storage disorder, unspecified
0.000 0.837 0.163
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.837 0.163
E75.3 Sphingolipidosis, unspecified
0.000 0.837 0.163
E75.2 Other sphingolipidosis
0.000 0.837 0.163
E75.1 Other gangliosidosis
0.000 0.837 0.163
E75.0 GM2 gangliosidosis
0.000 0.837 0.163
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.837 0.162
E72.0 Disorders of amino-acid transport
0.000 0.838 0.161
E34 Other endocrine disorders
0.000 0.839 0.161
E20.8 Other hypoparathyroidism
0.000 0.839 0.161
E20.1 Pseudohypoparathyroidism
0.000 0.839 0.161
E20.0 Idiopathic hypoparathyroidism
0.000 0.839 0.161
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.841 0.158
E14.7 With multiple complications
0.000 0.843 0.157
E14.0 With coma
0.000 0.843 0.157
E78.4 Other hyperlipidaemia
0.000 0.843 0.156
E29.9 Testicular dysfunction, unspecified
0.000 0.844 0.156
E29.8 Other testicular dysfunction
0.000 0.844 0.156
E29.0 Testicular hyperfunction
0.000 0.844 0.156
E78.1 Pure hyperglyceridaemia
0.000 0.845 0.155
K90.3 Pancreatic steatorrhoea
0.000 0.846 0.154
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.846 0.154
K90.1 Tropical sprue
0.000 0.846 0.154
E78.6 Lipoprotein deficiency
0.000 0.846 0.154
E75.5 Other lipid storage disorders
0.000 0.849 0.151
E14.6 With other specified complications
0.000 0.850 0.150
E14.1 With ketoacidosis
0.000 0.850 0.150
E11 Non-insulin-dependent diabetes mellitus
0.000 0.851 0.149
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.851 0.149
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.851 0.149
E79.1 Lesch-Nyhan syndrome
0.000 0.851 0.149
E78.3 Hyperchylomicronaemia
0.000 0.852 0.148
E26.0 Primary hyperaldosteronism
0.000 0.853 0.147
E24.8 Other Cushing's syndrome
0.000 0.853 0.147
E27.8 Other specified disorders of adrenal gland
0.000 0.853 0.147
E65 Localised adiposity
0.000 0.853 0.146
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.854 0.146
E24.3 Ectopic ACTH syndrome
0.000 0.854 0.146
E24.1 Nelson's syndrome
0.000 0.854 0.146
E24.0 Pituitary-dependent Cushing's disease
0.000 0.858 0.142
E11.2 With renal complications
0.000 0.860 0.140
E26.8 Other hyperaldosteronism
0.000 0.861 0.139
E26.1 Secondary hyperaldosteronism
0.000 0.861 0.139
E78.2 Mixed hyperlipidaemia
0.000 0.861 0.139
K90.8 Other intestinal malabsorption
0.000 0.862 0.138
E85 Amyloidosis
0.000 0.862 0.137
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.863 0.137
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.863 0.137
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.863 0.137
E74.2 Disorders of galactose metabolism
0.000 0.863 0.137
E74.1 Disorders of fructose metabolism
0.000 0.863 0.137
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.864 0.136
E25.9 Adrenogenital disorder, unspecified
0.000 0.865 0.135
E25.8 Other adrenogenital disorders
0.000 0.865 0.135
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.865 0.135
E30.9 Disorder of puberty, unspecified
0.000 0.865 0.135
E30.8 Other disorders of puberty
0.000 0.865 0.135
E30.1 Precocious puberty
0.000 0.865 0.135
E30.0 Delayed puberty
0.000 0.865 0.135
E31.9 Polyglandular dysfunction, unspecified
0.000 0.865 0.135
E31.8 Other polyglandular dysfunction
0.000 0.865 0.135
E31.1 Polyglandular hyperfunction
0.000 0.865 0.135
E31.0 Autoimmune polyglandular failure
0.000 0.865 0.135
E32.9 Disease of thymus, unspecified
0.000 0.865 0.135
E32.8 Other diseases of thymus
0.000 0.865 0.135
E32.1 Abscess of thymus
0.000 0.865 0.135
E32.0 Persistent hyperplasia of thymus
0.000 0.865 0.135
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.865 0.135
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.865 0.135
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.865 0.135
E26.9 Hyperaldosteronism, unspecified
0.000 0.865 0.135
E73.8 Other lactose intolerance
0.000 0.866 0.134
E73.1 Secondary lactase deficiency
0.000 0.866 0.134
E73.0 Congenital lactase deficiency
0.000 0.866 0.134
E67 Other hyperalimentation
0.000 0.868 0.131
E68 Sequelae of hyperalimentation
0.000 0.868 0.131
E34.9 Endocrine disorder, unspecified
0.000 0.870 0.130
E89.4 Postprocedural ovarian failure
0.000 0.872 0.128
E44.1 Mild protein-energy malnutrition
0.000 0.873 0.127
E44.0 Moderate protein-energy malnutrition
0.000 0.873 0.127
E83.4 Disorders of magnesium metabolism
0.000 0.873 0.127
E11.1 With ketoacidosis
0.000 0.877 0.123
E74.0 Glycogen storage disease
0.000 0.879 0.120
E14.8 With unspecified complications
0.000 0.882 0.118
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.882 0.117
E34.5 Androgen resistance syndrome
0.000 0.884 0.116
E34.4 Constitutional tall stature
0.000 0.884 0.116
E34.3 Short stature, not elsewhere classified
0.000 0.884 0.116
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.884 0.116
E34.1 Other hypersecretion of intestinal hormones
0.000 0.884 0.116
E14.4 With neurological complications
0.000 0.886 0.114
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.886 0.114
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.886 0.114
E89.5 Postprocedural testicular hypofunction
0.000 0.886 0.114
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.887 0.113
E24.9 Cushing's syndrome, unspecified
0.000 0.890 0.110
E11.6 With other specified complications
0.000 0.892 0.108
E23 Hypofunction and other disorders of pituitary gland
0.000 0.893 0.107
E11.7 With multiple complications
0.000 0.893 0.107
E11.0 With coma
0.000 0.894 0.106
E11.8 With unspecified complications
0.000 0.895 0.105
E89.1 Postprocedural hypoinsulinaemia
0.000 0.896 0.104
E78.8 Other disorders of lipoprotein metabolism
0.000 0.900 0.100
E34.0 Carcinoid syndrome
0.000 0.900 0.100
E85.8 Other amyloidosis
0.000 0.901 0.098
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.901 0.098
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.901 0.098
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.901 0.098
E22 Hyperfunction of pituitary gland
0.000 0.904 0.096
E28 Ovarian dysfunction
0.000 0.905 0.095
E27.9 Disorder of adrenal gland, unspecified
0.001 0.905 0.095
E89.0 Postprocedural hypothyroidism
0.000 0.905 0.095
E67.8 Other specified hyperalimentation
0.000 0.905 0.094
E67.3 Hypervitaminosis D
0.000 0.905 0.094
E67.2 Megavitamin-B6 syndrome
0.000 0.905 0.094
E67.1 Hypercarotenaemia
0.000 0.905 0.094
E67.0 Hypervitaminosis A
0.000 0.905 0.094
E11.5 With peripheral circulatory complications
0.000 0.914 0.086
E23.2 Diabetes insipidus
0.000 0.914 0.086
E34.8 Other specified endocrine disorders
0.000 0.916 0.083
E73.9 Lactose intolerance, unspecified
0.000 0.917 0.082
E11.4 With neurological complications
0.000 0.918 0.082
E85.9 Amyloidosis, unspecified
0.000 0.918 0.082
E83.5 Disorders of calcium metabolism
0.000 0.918 0.082
E85.3 Secondary systemic amyloidosis
0.000 0.918 0.081
M25.57 Pain in joint (Ankle and foot)
0.000 0.919 0.081
E23.1 Drug-induced hypopituitarism
0.000 0.923 0.077
E23.7 Disorder of pituitary gland, unspecified
0.000 0.924 0.076
E22.1 Hyperprolactinaemia
0.000 0.928 0.072
E85.4 Organ-limited amyloidosis
0.000 0.930 0.070
E23.6 Other disorders of pituitary gland
0.000 0.931 0.069
E22.8 Other hyperfunction of pituitary gland
0.000 0.931 0.069
E50-E64 Other nutritional deficiencies
0.000 0.931 0.069
E28.9 Ovarian dysfunction, unspecified
0.000 0.931 0.068
E28.8 Other ovarian dysfunction
0.000 0.931 0.068
E28.1 Androgen excess
0.000 0.931 0.068
E28.0 Oestrogen excess
0.000 0.931 0.068
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.935 0.064
E89.2 Postprocedural hypoparathyroidism
0.000 0.936 0.064
E89.3 Postprocedural hypopituitarism
0.000 0.938 0.061
E00-E07 Disorders of thyroid gland
0.000 0.938 0.062
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.940 0.059
K90.9 Intestinal malabsorption, unspecified
0.001 0.944 0.056
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.950 0.049
E63 Other nutritional deficiencies
0.000 0.950 0.049
E50 Vitamin A deficiency
0.000 0.950 0.049
E60 Dietary zinc deficiency
0.000 0.950 0.049
E59 Dietary selenium deficiency
0.000 0.950 0.049
E52 Niacin deficiency [pellagra]
0.000 0.950 0.049
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.951 0.049
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.953 0.047
E51 Thiamine deficiency
0.000 0.953 0.047
E56 Other vitamin deficiencies
0.000 0.953 0.046
M25.5 Pain in joint
0.000 0.954 0.046
E58 Dietary calcium deficiency
0.000 0.954 0.046
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.956 0.044
E00 Congenital iodine-deficiency syndrome
0.000 0.956 0.044
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.957 0.043
E53 Deficiency of other B group vitamins
0.000 0.957 0.043
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.958 0.042
E54 Ascorbic acid deficiency
0.000 0.958 0.041
E28.3 Primary ovarian failure
0.001 0.960 0.040
E07 Other disorders of thyroid
0.000 0.960 0.040
M25.51 Pain in joint (Shoulder region)
0.000 0.960 0.040
E22.0 Acromegaly and pituitary gigantism
0.000 0.961 0.039
E11.3 With ophthalmic complications
0.000 0.962 0.038
M25.58 Pain in joint (Other)
0.000 0.962 0.038
E28.2 Polycystic ovarian syndrome
0.000 0.963 0.036
E06 Thyroiditis
0.000 0.963 0.037
E55 Vitamin D deficiency
0.000 0.963 0.037
M25.52 Pain in joint (Upper arm)
0.000 0.963 0.037
E66 Obesity
0.000 0.964 0.036
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.964 0.036
E50.9 Vitamin A deficiency, unspecified
0.000 0.964 0.036
E50.8 Other manifestations of vitamin A deficiency
0.000 0.964 0.036
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.964 0.036
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.964 0.036
E50.5 Vitamin A deficiency with night blindness
0.000 0.964 0.036
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.964 0.036
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.964 0.036
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.964 0.036
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.964 0.036
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.964 0.036
E63.9 Nutritional deficiency, unspecified
0.000 0.964 0.036
E63.8 Other specified nutritional deficiencies
0.000 0.964 0.036
E63.1 Imbalance of constituents of food intake
0.000 0.964 0.036
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.964 0.036
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.964 0.036
E64.8 Sequelae of other nutritional deficiencies
0.000 0.964 0.036
E64.3 Sequelae of rickets
0.000 0.964 0.036
E64.2 Sequelae of vitamin C deficiency
0.000 0.964 0.036
E64.1 Sequelae of vitamin A deficiency
0.000 0.964 0.036
E64.0 Sequelae of protein-energy malnutrition
0.000 0.964 0.036
M25.53 Pain in joint (Forearm)
0.000 0.966 0.034
E51.9 Thiamine deficiency, unspecified
0.000 0.966 0.034
E51.8 Other manifestations of thiamine deficiency
0.000 0.966 0.034
E51.1 Beriberi
0.000 0.966 0.034
E56.9 Vitamin deficiency, unspecified
0.000 0.966 0.033
E56.8 Deficiency of other vitamins
0.000 0.966 0.033
E56.0 Deficiency of vitamin E
0.000 0.966 0.033
E53.9 Vitamin B deficiency, unspecified
0.000 0.966 0.034
E05.8 Other thyrotoxicosis
0.000 0.966 0.034
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.967 0.033
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.968 0.032
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.968 0.032
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.968 0.032
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.968 0.032
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.968 0.032
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.968 0.032
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.968 0.032
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.968 0.032
E21.2 Other hyperparathyroidism
0.000 0.969 0.031
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.969 0.031
E53.1 Pyridoxine deficiency
0.000 0.969 0.031
E53.0 Riboflavin deficiency
0.000 0.969 0.031
E51.2 Wernicke's encephalopathy
0.000 0.969 0.031
E56.1 Deficiency of vitamin K
0.000 0.969 0.030
E61 Deficiency of other nutrient elements
0.001 0.970 0.030
E05.5 Thyroid crisis or storm
0.000 0.970 0.030
E05.4 Thyrotoxicosis factitia
0.000 0.970 0.030
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.970 0.030
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.970 0.030
E21.4 Other specified disorders of parathyroid gland
0.000 0.970 0.029
E04 Other non-toxic goitre
0.000 0.971 0.029
E07.1 Dyshormogenetic goitre
0.000 0.971 0.029
E07.0 Hypersecretion of calcitonin
0.000 0.971 0.029
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.971 0.029
E06.5 Other chronic thyroiditis
0.000 0.971 0.028
E07.8 Other specified disorders of thyroid
0.000 0.972 0.028
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.973 0.027
E03 Other hypothyroidism
0.000 0.973 0.027
E14.9 Without complications
0.000 0.973 0.027
E06.4 Drug-induced thyroiditis
0.000 0.973 0.027
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.973 0.027
E06.0 Acute thyroiditis
0.000 0.973 0.027
E55.0 Rickets, active
0.000 0.973 0.026
E66.1 Drug-induced obesity
0.000 0.974 0.026
E07.9 Disorder of thyroid, unspecified
0.000 0.974 0.026
E06.1 Subacute thyroiditis
0.000 0.975 0.025
E04.0 Non-toxic diffuse goitre
0.000 0.975 0.025
E06.3 Autoimmune thyroiditis
0.000 0.976 0.024
M25.59 Pain in joint (Site unspecified)
0.000 0.976 0.024
E04.9 Non-toxic goitre, unspecified
0.000 0.977 0.023
E66.0 Obesity due to excess calories
0.000 0.977 0.023
E61.9 Deficiency of nutrient element, unspecified
0.001 0.978 0.022
E61.8 Deficiency of other specified nutrient elements
0.001 0.978 0.022
E61.7 Deficiency of multiple nutrient elements
0.001 0.978 0.022
E61.6 Vanadium deficiency
0.001 0.978 0.022
E61.5 Molybdenum deficiency
0.001 0.978 0.022
E61.4 Chromium deficiency
0.001 0.978 0.022
E61.3 Manganese deficiency
0.001 0.978 0.022
E61.0 Copper deficiency
0.001 0.978 0.022
E04.8 Other specified non-toxic goitre
0.000 0.979 0.021
E23.0 Hypopituitarism
0.001 0.979 0.020
E06.9 Thyroiditis, unspecified
0.000 0.979 0.021
E61.2 Magnesium deficiency
0.001 0.979 0.020
E21.0 Primary hyperparathyroidism
0.000 0.979 0.020
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.980 0.020
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.980 0.020
E03.5 Myxoedema coma
0.000 0.980 0.019
E03.4 Atrophy of thyroid (acquired)
0.000 0.980 0.019
E03.3 Postinfectious hypothyroidism
0.000 0.980 0.019
E03.8 Other specified hypothyroidism
0.000 0.981 0.019
M25.54 Pain in joint (Hand)
0.000 0.981 0.019
E53.8 Deficiency of other specified B group vitamins
0.000 0.981 0.019
E03.1 Congenital hypothyroidism without goitre
0.000 0.981 0.019
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.982 0.017
E86 Volume depletion
0.000 0.983 0.017
K90-K93 Other diseases of the digestive system
0.000 0.983 0.017
G30.9 Alzheimer's disease, unspecified
0.000 0.985 0.015
M25.50 Pain in joint (Multiple sites)
0.000 0.985 0.015
E05.9 Thyrotoxicosis, unspecified
0.000 0.985 0.015
E55.9 Vitamin D deficiency, unspecified
0.000 0.986 0.013
G30 Alzheimer's disease
0.000 0.986 0.014
G31.8 Other specified degenerative diseases of nervous system
0.000 0.987 0.013
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.988 0.012
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.988 0.012
E21.3 Hyperparathyroidism, unspecified
0.000 0.988 0.012
G30.0 Alzheimer's disease with early onset
0.000 0.989 0.011
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.989 0.011
G30-G32 Other degenerative diseases of the nervous system
0.000 0.989 0.011
G31.0 Circumscribed brain atrophy
0.000 0.989 0.011
K56.4 Other impaction of intestine
0.011 0.989 0.000
G30.8 Other Alzheimer's disease
0.000 0.990 0.010
G30.1 Alzheimer's disease with late onset
0.000 0.990 0.010
E66.9 Obesity, unspecified
0.000 0.990 0.010
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.990 0.010
E04.1 Non-toxic single thyroid nodule
0.000 0.991 0.009
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.991 0.009
K93.1 Megacolon in Chagas' disease
0.000 0.991 0.009
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.991 0.009
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.991 0.009
E87.3 Alkalosis
0.000 0.991 0.008
E04.2 Non-toxic multinodular goitre
0.000 0.992 0.008
E87.4 Mixed disorder of acid-base balance
0.000 0.992 0.008
E87.7 Fluid overload
0.000 0.992 0.008
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.992 0.008
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.992 0.008
M94.86 Other specified disorders of cartilage (Lower leg)
0.007 0.993 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.000 0.993 0.007
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.007 0.993 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.007 0.993 0.000
E61.1 Iron deficiency
0.001 0.993 0.006
E87.5 Hyperkalaemia
0.000 0.993 0.007
G31.2 Degeneration of nervous system due to alcohol
0.000 0.993 0.006
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.994 0.006
M94.8 Other specified disorders of cartilage
0.006 0.994 0.000
M25.56 Pain in joint (Lower leg)
0.000 0.994 0.006
F06.7 Mild cognitive disorder
0.006 0.994 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.995 0.005
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)
0.005 0.995 0.000
E87.2 Acidosis
0.000 0.995 0.005
K51.2 Ulcerative (chronic) proctitis
0.005 0.995 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.995 0.005
M94.89 Other specified disorders of cartilage (Site unspecified)
0.005 0.995 0.000
O63.1 Prolonged second stage (of labour)
0.005 0.995 0.000
E11.9 Without complications
0.000 0.995 0.005
K63.3 Ulcer of intestine
0.005 0.995 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.995 0.005
Z34.9 Supervision of normal pregnancy, unspecified
0.005 0.995 0.000
M94.84 Other specified disorders of cartilage (Hand)
0.004 0.995 0.000
M94.83 Other specified disorders of cartilage (Forearm)
0.004 0.995 0.000
M94.82 Other specified disorders of cartilage (Upper arm)
0.004 0.995 0.000
M94.81 Other specified disorders of cartilage (Shoulder region)
0.004 0.995 0.000
M94.80 Other specified disorders of cartilage (Multiple sites)
0.004 0.995 0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)
0.004 0.995 0.000
M94.88 Other specified disorders of cartilage (Other)
0.004 0.995 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.996 0.004
R49.0 Dysphonia
0.000 0.996 0.004
Z53.0 Procedure not carried out because of contraindication
0.000 0.996 0.004
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.996 0.004
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.004 0.996 0.000
H20.9 Iridocyclitis, unspecified
0.000 0.996 0.004
M41.9 Scoliosis, unspecified
0.004 0.996 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.004 0.996 0.000
K02.9 Dental caries, unspecified
0.000 0.996 0.004
K91.5 Postcholecystectomy syndrome
0.000 0.996 0.004
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.004 0.996 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.004 0.996 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.996 0.004
M94 Other disorders of cartilage
0.004 0.996 0.000
G44.2 Tension-type headache
0.004 0.996 0.000
G82.5 Tetraplegia, unspecified
0.000 0.996 0.004
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.004 0.996 0.000
K91.3 Postoperative intestinal obstruction
0.000 0.997 0.003
M94.0 Chondrocostal junction syndrome [Tietze]
0.003 0.997 0.000
G82.4 Spastic tetraplegia
0.000 0.997 0.003
M13.90 Arthritis, unspecified (Multiple sites)
0.000 0.997 0.003
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease
0.003 0.997 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.997 0.003
R27.0 Ataxia, unspecified
0.000 0.997 0.003
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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