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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2294324
log Bayes Factor = 16.4277
Chromosome 6   position 166,891,600  (GRCh37) Explore rs2294324 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
M50-M54 Other dorsopathies
0.996 0.004 0.000
M70-M79 Other soft tissue disorders
0.988 0.012 0.000
M05-M14 Inflammatory polyarthropathies
0.988 0.012 0.000
J09-J18 Influenza and pneumonia
0.986 0.014 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.985 0.015 0.000
Chapter I Certain infectious and parasitic diseases
0.984 0.016 0.000
J18 Pneumonia, organism unspecified
0.979 0.021 0.000
N30-N39 Other diseases of urinary system
0.978 0.022 0.000
Chapter XIV Diseases of the genitourinary system
0.978 0.022 0.000
N39 Other disorders of urinary system
0.976 0.024 0.000
M54 Dorsalgia
0.974 0.026 0.000
M13 Other arthritis
0.972 0.028 0.000
J18.1 Lobar pneumonia, unspecified
0.971 0.029 0.000
M25 Other joint disorders, not elsewhere classified
0.970 0.030 0.000
N39.3 Stress incontinence
0.968 0.032 0.000
M51 Other intervertebral disk disorders
0.967 0.033 0.000
Chapter V Mental and behavioural disorders
0.961 0.039 0.000
M13.9 Arthritis, unspecified
0.960 0.040 0.000
M54.5 Low back pain
0.953 0.047 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.952 0.048 0.000
N35 Urethral stricture
0.951 0.049 0.000
G40-G47 Episodic and paroxysmal disorders
0.950 0.050 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.949 0.051 0.000
M80-M85 Disorders of bone density and structure
0.947 0.053 0.000
M40-M43 Deforming dorsopathies
0.947 0.053 0.000
M51.2 Other specified intervertebral disk displacement
0.946 0.054 0.000
B95-B98 Bacterial, viral and other infectious agents
0.938 0.062 0.000
N35.9 Urethral stricture, unspecified
0.931 0.069 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.927 0.073 0.000
M75 Shoulder lesions
0.924 0.076 0.000
Chapter XX External causes of morbidity and mortality
0.921 0.079 0.000
J90-J94 Other diseases of pleura
0.919 0.081 0.000
N39.4 Other specified urinary incontinence
0.918 0.082 0.000
G90-G99 Other disorders of the nervous system
0.918 0.082 0.000
M45-M49 Spondylopathies
0.912 0.088 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.908 0.092 0.000
J95-J99 Other diseases of the respiratory system
0.904 0.096 0.000
S60-S69 Injuries to the wrist and hand
0.904 0.096 0.000
M23 Internal derangement of knee
0.898 0.102 0.000
M65-M68 Disorders of synovium and tendon
0.897 0.103 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.896 0.104 0.000
M10 Gout
0.895 0.105 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.893 0.107 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.892 0.108 0.000
G40 Epilepsy
0.891 0.109 0.000
O60-O75 Complications of labour and delivery
0.888 0.112 0.000
M54.57 Low back pain (Lumbosacral region)
0.884 0.116 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.877 0.123 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.877 0.123 0.000
S80-S89 Injuries to the knee and lower leg
0.875 0.125 0.000
M54.56 Low back pain (Lumbar region)
0.874 0.126 0.000
S70-S79 Injuries to the hip and thigh
0.872 0.128 0.000
M81 Osteoporosis without pathological fracture
0.872 0.128 0.000
M20 Acquired deformities of fingers and toes
0.867 0.133 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.867 0.133 0.000
M22 Disorders of patella
0.866 0.134 0.000
Chapter VIII Diseases of the ear and mastoid process
0.865 0.135 0.000
G20-G26 Extrapyramidal and movement disorders
0.862 0.138 0.000
M75.1 Rotator cuff syndrome
0.859 0.141 0.000
M25.8 Other specified joint disorders
0.857 0.143 0.000
M43 Other deforming dorsopathies
0.857 0.143 0.000
M25.7 Osteophyte
0.855 0.145 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.855 0.145 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.853 0.147 0.000
S32 Fracture of lumbar spine and pelvis
0.851 0.149 0.000
B35-B49 Mycoses
0.850 0.150 0.000
N39.9 Disorder of urinary system, unspecified
0.845 0.155 0.000
O00-O08 Pregnancy with abortive outcome
0.843 0.157 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.842 0.158 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.840 0.160 0.000
M79.0 Rheumatism, unspecified
0.839 0.161 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.839 0.161 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.836 0.164 0.000
M41 Scoliosis
0.833 0.166 0.000
M79.8 Other specified soft tissue disorders
0.833 0.167 0.000
M10.9 Gout, unspecified
0.829 0.171 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.824 0.176 0.000
M13.94 Arthritis, unspecified (Hand)
0.823 0.177 0.000
M31 Other necrotising vasculopathies
0.821 0.179 0.000
Chapter VII Diseases of the eye and adnexa
0.820 0.180 0.000
M81.9 Osteoporosis, unspecified
0.818 0.182 0.000
J18.9 Pneumonia, unspecified
0.817 0.183 0.000
M48 Other spondylopathies
0.814 0.186 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.813 0.187 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.812 0.188 0.000
N30 Cystitis
0.812 0.188 0.000
J93 Pneumothorax
0.811 0.189 0.000
L50-L54 Urticaria and erythema
0.810 0.190 0.000
M20.1 Hallux valgus (acquired)
0.810 0.190 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.809 0.191 0.000
N17-N19 Renal failure
0.808 0.192 0.000
J30-J39 Other diseases of upper respiratory tract
0.807 0.193 0.000
J94 Other pleural conditions
0.807 0.193 0.000
M25.76 Osteophyte (Lower leg)
0.806 0.193 0.000
A30-A49 Other bacterial diseases
0.805 0.195 0.000
M15-M19 Arthrosis
0.804 0.196 0.000
G83 Other paralytic syndromes
0.804 0.196 0.000
M67 Other disorders of synovium and tendon
0.803 0.197 0.000
J98 Other respiratory disorders
0.802 0.198 0.000
G91 Hydrocephalus
0.796 0.204 0.000
L08 Other local infections of skin and subcutaneous tissue
0.795 0.205 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.794 0.206 0.000
T66-T78 Other and unspecified effects of external causes
0.794 0.206 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.793 0.206 0.000
M79.6 Pain in limb
0.793 0.207 0.000
M54.4 Lumbago with sciatica
0.793 0.207 0.000
M43.1 Spondylolisthesis
0.793 0.207 0.000
M25.4 Effusion of joint
0.791 0.209 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.787 0.213 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.786 0.213 0.000
M25.5 Pain in joint
0.785 0.215 0.000
G93 Other disorders of brain
0.784 0.216 0.000
M10.99 Gout, unspecified (Site unspecified)
0.784 0.216 0.000
M84 Disorders of continuity of bone
0.781 0.219 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.779 0.221 0.000
M13.98 Arthritis, unspecified (Other)
0.779 0.221 0.000
Y95 Nosocomial condition
0.775 0.225 0.000
B15-B19 Viral hepatitis
0.773 0.227 0.000
Chapter XXII Codes for special purposes
0.772 0.228 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.771 0.229 0.000
O72 Postpartum haemorrhage
0.767 0.232 0.000
F30-F39 Mood [affective] disorders
0.767 0.233 0.000
J92 Pleural plaque
0.766 0.234 0.000
S82 Fracture of lower leg, including ankle
0.765 0.235 0.000
G20 Parkinson's disease
0.765 0.235 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.765 0.235 0.000
J32 Chronic sinusitis
0.764 0.236 0.000
S32.5 Fracture of pubis
0.764 0.236 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.762 0.238 0.000
M17 Gonarthrosis [arthrosis of knee]
0.760 0.240 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.760 0.240 0.000
M75.3 Calcific tendinitis of shoulder
0.760 0.240 0.000
J60-J70 Lung diseases due to external agents
0.758 0.242 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.757 0.243 0.000
G47 Sleep disorders
0.757 0.243 0.000
M47 Spondylosis
0.756 0.244 0.000
M21 Other acquired deformities of limbs
0.755 0.245 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.755 0.245 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.754 0.246 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.753 0.247 0.000
S20-S29 Injuries to the thorax
0.753 0.247 0.000
M41.9 Scoliosis, unspecified
0.752 0.248 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.752 0.248 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.752 0.248 0.000
M71 Other bursopathies
0.751 0.249 0.000
M54.59 Low back pain (Site unspecified)
0.749 0.251 0.000
N19 Unspecified renal failure
0.749 0.251 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.748 0.252 0.000
S64 Injury of nerves at wrist and hand level
0.748 0.252 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.747 0.253 0.000
N00-N08 Glomerular diseases
0.747 0.253 0.000
N25-N29 Other disorders of kidney and ureter
0.747 0.253 0.000
A80-A89 Viral infections of the central nervous system
0.746 0.253 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.746 0.254 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.744 0.256 0.000
M48.0 Spinal stenosis
0.744 0.256 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.743 0.257 0.000
M23.3 Other meniscus derangements
0.742 0.257 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.742 0.258 0.000
G83.4 Cauda equina syndrome
0.742 0.258 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.740 0.260 0.000
S32.0 Fracture of lumbar vertebra
0.740 0.260 0.000
G40.8 Other epilepsy
0.740 0.260 0.000
M51.8 Other specified intervertebral disk disorders
0.739 0.261 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.738 0.262 0.000
F03 Unspecified dementia
0.737 0.263 0.000
M67.8 Other specified disorders of synovium and tendon
0.736 0.264 0.000
M91-M94 Chondropathies
0.736 0.264 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.736 0.264 0.000
S79 Other and unspecified injuries of hip and thigh
0.735 0.265 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.734 0.266 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.734 0.266 0.000
S90-S99 Injuries to the ankle and foot
0.731 0.269 0.000
F99-F99 Unspecified mental disorder
0.731 0.269 0.000
G30-G32 Other degenerative diseases of the nervous system
0.729 0.270 0.000
L53 Other erythematous conditions
0.729 0.271 0.000
M35 Other systemic involvement of connective tissue
0.729 0.271 0.000
M79.1 Myalgia
0.729 0.271 0.000
G35 Multiple sclerosis
0.728 0.272 0.000
N99-N99 Other disorders of the genitourinary system
0.728 0.272 0.000
M80 Osteoporosis with pathological fracture
0.727 0.273 0.000
H65-H75 Diseases of middle ear and mastoid
0.727 0.273 0.000
S65 Injury of blood vessels at wrist and hand level
0.726 0.274 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.726 0.274 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.725 0.275 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.725 0.275 0.000
M17.0 Primary gonarthrosis, bilateral
0.725 0.275 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.722 0.278 0.000
G62 Other polyneuropathies
0.720 0.280 0.000
M54.2 Cervicalgia
0.720 0.280 0.000
L05 Pilonidal cyst
0.719 0.281 0.000
M22.8 Other disorders of patella
0.718 0.282 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.283 0.000
S40-S49 Injuries to the shoulder and upper arm
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M34 Systemic sclerosis
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.716 0.284 0.000
M20.3 Other deformity of hallux (acquired)
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.715 0.285 0.000
M53 Other dorsopathies, not elsewhere classified
0.714 0.286 0.000
M13.0 Polyarthritis, unspecified
0.713 0.287 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.713 0.287 0.000
M79.66 Pain in limb (Lower leg)
0.713 0.287 0.000
S69 Other and unspecified injuries of wrist and hand
0.713 0.287 0.000
M23.5 Chronic instability of knee
0.713 0.287 0.000
O44 Placenta praevia
0.712 0.288 0.000
F60-F69 Disorders of adult personality and behaviour
0.711 0.288 0.000
M75.0 Adhesive capsulitis of shoulder
0.711 0.289 0.000
F80-F89 Disorders of psychological development
0.709 0.291 0.000
M76 Enthesopathies of lower limb, excluding foot
0.708 0.291 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.708 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.708 0.292 0.000
M12 Other specific arthropathies
0.708 0.292 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.708 0.292 0.000
M08 Juvenile arthritis
0.708 0.292 0.000
N39.8 Other specified disorders of urinary system
0.708 0.292 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.708 0.292 0.000
S60 Superficial injury of wrist and hand
0.708 0.292 0.000
J17 Pneumonia in diseases classified elsewhere
0.707 0.293 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.707 0.293 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.707 0.293 0.000
J12 Viral pneumonia, not elsewhere classified
0.707 0.293 0.000
J11 Influenza, virus not identified
0.707 0.293 0.000
J10 Influenza due to identified influenza virus
0.707 0.293 0.000
J14 Pneumonia due to Haemophilus influenzae
0.707 0.293 0.000
J09 Influenza due to certain identified influenza virus
0.707 0.293 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.707 0.293 0.000
N30.8 Other cystitis
0.707 0.293 0.000
O85-O92 Complications predominantly related to the puerperium
0.706 0.294 0.000
X50-X57 Overexertion, travel and privation
0.706 0.294 0.000
B99-B99 Other infectious diseases
0.706 0.294 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.294 0.000
B65-B83 Helminthiases
0.706 0.294 0.000
B50-B64 Protozoal diseases
0.706 0.294 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A65-A69 Other spirochaetal diseases
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
A15-A19 Tuberculosis
0.706 0.294 0.000
S89 Other and unspecified injuries of lower leg
0.706 0.294 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.705 0.295 0.000
M05 Seropositive rheumatoid arthritis
0.705 0.295 0.000
M11 Other crystal arthropathies
0.705 0.295 0.000
G70-G73 Diseases of myoneural junction and muscle
0.704 0.296 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.704 0.296 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.704 0.296 0.000
M86-M90 Other osteopathies
0.704 0.296 0.000
J18.8 Other pneumonia, organism unspecified
0.702 0.298 0.000
J18.2 Hypostatic pneumonia, unspecified
0.702 0.298 0.000
S32.50 Fracture of pubis (closed)
0.701 0.299 0.000
N37 Urethral disorders in diseases classified elsewhere
0.701 0.299 0.000
N34 Urethritis and urethral syndrome
0.701 0.299 0.000
N33 Bladder disorders in diseases classified elsewhere
0.701 0.299 0.000
B49 Unspecified mycosis
0.701 0.299 0.000
T91 Sequelae of injuries of neck and trunk
0.701 0.299 0.000
O70 Perineal laceration during delivery
0.700 0.300 0.000
M77 Other enthesopathies
0.700 0.300 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.700 0.300 0.000
N39.2 Orthostatic proteinuria, unspecified
0.700 0.300 0.000
N39.1 Persistent proteinuria, unspecified
0.700 0.300 0.000
G37 Other demyelinating diseases of central nervous system
0.699 0.301 0.000
O66 Other obstructed labour
0.698 0.302 0.000
M54.8 Other dorsalgia
0.698 0.302 0.000
M54.6 Pain in thoracic spine
0.698 0.302 0.000
M54.0 Panniculitis affecting regions of neck and back
0.698 0.302 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.698 0.302 0.000
S70 Superficial injury of hip and thigh
0.698 0.302 0.000
M65 Synovitis and tenosynovitis
0.697 0.303 0.000
M13.8 Other specified arthritis
0.697 0.303 0.000
M13.1 Monoarthritis, not elsewhere classified
0.697 0.303 0.000
S50-S59 Injuries to the elbow and forearm
0.697 0.303 0.000
N60-N64 Disorders of breast
0.697 0.303 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.697 0.303 0.000
M25.86 Other specified joint disorders (Lower leg)
0.696 0.304 0.000
G44 Other headache syndromes
0.696 0.304 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.695 0.305 0.000
M25.9 Joint disorder, unspecified
0.695 0.305 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.695 0.305 0.000
M25.3 Other instability of joint
0.695 0.305 0.000
M25.2 Flail joint
0.695 0.305 0.000
M25.1 Fistula of joint
0.695 0.305 0.000
M25.0 Haemarthrosis
0.695 0.305 0.000
M79.5 Residual foreign body in soft tissue
0.693 0.307 0.000
Y85 Sequelae of transport accidents
0.693 0.307 0.000
M51.3 Other specified intervertebral disk degeneration
0.693 0.307 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.693 0.307 0.000
M51.9 Intervertebral disk disorder, unspecified
0.693 0.307 0.000
M51.4 Schmorl's nodes
0.693 0.307 0.000
G45.4 Transient global amnesia
0.693 0.307 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.693 0.307 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.692 0.308 0.000
J32.0 Chronic maxillary sinusitis
0.692 0.308 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.690 0.310 0.000
O00 Ectopic pregnancy
0.690 0.310 0.000
T92 Sequelae of injuries of upper limb
0.690 0.310 0.000
M20.4 Other hammer toe(s) (acquired)
0.690 0.310 0.000
M54.3 Sciatica
0.689 0.311 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.689 0.311 0.000
F70-F79 Mental retardation
0.689 0.311 0.000
T90 Sequelae of injuries of head
0.689 0.311 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.689 0.311 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.688 0.312 0.000
M13.93 Arthritis, unspecified (Forearm)
0.688 0.312 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.688 0.312 0.000
T98 Sequelae of other and unspecified effects of external causes
0.688 0.312 0.000
S86 Injury of muscle and tendon at lower leg level
0.688 0.312 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.686 0.314 0.000
M22.2 Patellofemoral disorders
0.685 0.315 0.000
J94.2 Haemothorax
0.685 0.315 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.684 0.316 0.000
V10-V19 Pedal cyclist injured in transport accident
0.684 0.316 0.000
M54.55 Low back pain (Thoracolumbar region)
0.683 0.317 0.000
M54.54 Low back pain-Thoracic
0.683 0.317 0.000
M54.53 Low back pain-Cervicothoracic
0.683 0.317 0.000
M54.52 Low back pain-Cervical
0.683 0.317 0.000
M54.51 Low back pain-Occipit-atl-axl
0.683 0.317 0.000
M54.50 Low back pain (Multiple sites in spine)
0.683 0.317 0.000
B35 Dermatophytosis
0.683 0.317 0.000
H25-H28 Disorders of lens
0.683 0.317 0.000
M25.57 Pain in joint (Ankle and foot)
0.682 0.318 0.000
M75.5 Bursitis of shoulder
0.682 0.318 0.000
N35.8 Other urethral stricture
0.682 0.318 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.682 0.318 0.000
N35.0 Posttraumatic urethral stricture
0.682 0.318 0.000
F22 Persistent delusional disorders
0.681 0.319 0.000
M54.1 Radiculopathy
0.681 0.319 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.681 0.319 0.000
G41 Status epilepticus
0.681 0.319 0.000
M24 Other specific joint derangements
0.680 0.319 0.000
M79.9 Soft tissue disorder, unspecified
0.680 0.320 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.680 0.320 0.000
M79.3 Panniculitis, unspecified
0.680 0.320 0.000
M79.2 Neuralgia and neuritis, unspecified
0.680 0.320 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.679 0.321 0.000
O03 Spontaneous abortion
0.679 0.321 0.000
J93.9 Pneumothorax, unspecified
0.679 0.321 0.000
M42 Spinal osteochondrosis
0.679 0.321 0.000
M40 Kyphosis and lordosis
0.679 0.321 0.000
M85 Other disorders of bone density and structure
0.679 0.321 0.000
M83 Adult osteomalacia
0.679 0.321 0.000
M82 Osteoporosis in diseases classified elsewhere
0.679 0.321 0.000
M31.6 Other giant cell arteritis
0.678 0.322 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.678 0.322 0.000
J93.1 Other spontaneous pneumothorax
0.678 0.322 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.677 0.323 0.000
G91.9 Hydrocephalus, unspecified
0.677 0.323 0.000
M50 Cervical disk disorders
0.676 0.324 0.000
G82 Paraplegia and tetraplegia
0.676 0.324 0.000
O30 Multiple gestation
0.674 0.326 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.673 0.327 0.000
L53.9 Erythematous condition, unspecified
0.672 0.328 0.000
G95 Other diseases of spinal cord
0.672 0.328 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.671 0.329 0.000
J98.4 Other disorders of lung
0.671 0.329 0.000
F05.9 Delirium, unspecified
0.670 0.330 0.000
N10-N16 Renal tubulo-interstitial diseases
0.670 0.330 0.000
H90-H95 Other disorders of ear
0.670 0.330 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.670 0.330 0.000
M23.4 Loose body in knee
0.668 0.332 0.000
O47 False labour
0.668 0.332 0.000
M45 Ankylosing spondylitis
0.667 0.333 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.666 0.334 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.666 0.334 0.000
F00 Dementia in Alzheimer's disease
0.666 0.334 0.000
L40-L45 Papulosquamous disorders
0.665 0.335 0.000
L10-L14 Bullous disorders
0.665 0.335 0.000
M25.46 Effusion of joint (Lower leg)
0.663 0.337 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.662 0.337 0.000
M75.8 Other shoulder lesions
0.662 0.338 0.000
M75.9 Shoulder lesion, unspecified
0.662 0.338 0.000
M75.2 Bicipital tendinitis
0.662 0.338 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.661 0.339 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.660 0.340 0.000
Y35-Y36 Legal intervention and operations of war
0.660 0.340 0.000
Y10-Y34 Event of undetermined intent
0.660 0.340 0.000
Y00-Y09 Assault
0.660 0.340 0.000
X85-X99 Assault
0.660 0.340 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.660 0.340 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.660 0.340 0.000
X30-X39 Exposure to forces of nature
0.660 0.340 0.000
X10-X19 Contact with heat and hot substances
0.660 0.340 0.000
X00-X09 Exposure to smoke, fire and flames
0.660 0.340 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.660 0.340 0.000
W75-W84 Other accidental threats to breathing
0.660 0.340 0.000
W65-W74 Accidental drowning and submersion
0.660 0.340 0.000
W50-W64 Exposure to animate mechanical forces
0.660 0.340 0.000
V98-V99 Other and unspecified transport accidents
0.660 0.340 0.000
V95-V97 Air and space transport accidents
0.660 0.340 0.000
V90-V94 Water transport accidents
0.660 0.340 0.000
V80-V89 Other land transport accidents
0.660 0.340 0.000
V70-V79 Bus occupant injured in transport accident
0.660 0.340 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.660 0.340 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.660 0.340 0.000
V40-V49 Car occupant injured in transport accident
0.660 0.340 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.660 0.340 0.000
V01-V09 Pedestrian injured in transport accident
0.660 0.340 0.000
M48.06 Spinal stenosis (Lumbar region)
0.660 0.340 0.000
M07 Psoriatic and enteropathic arthropathies
0.660 0.340 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.660 0.340 0.000
Chapter II Neoplasms
0.659 0.341 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.659 0.341 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.658 0.342 0.000
G96 Other disorders of central nervous system
0.658 0.342 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.658 0.342 0.000
G90 Disorders of autonomic nervous system
0.658 0.342 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.658 0.342 0.000
G92 Toxic encephalopathy
0.658 0.342 0.000
Y88 Sequelae of surgical and medical care as external cause
0.657 0.343 0.000
B07 Viral warts
0.657 0.343 0.000
J18.0 Bronchopneumonia, unspecified
0.657 0.343 0.000
S00-S09 Injuries to the head
0.657 0.343 0.000
J94.8 Other specified pleural conditions
0.656 0.344 0.000
G93.9 Disorder of brain, unspecified
0.656 0.344 0.000
M79.60 Pain in limb (Multiple sites)
0.656 0.344 0.000
O80-O84 Delivery
0.655 0.345 0.000
M25.59 Pain in joint (Site unspecified)
0.654 0.346 0.000
M49 Spondylopathies in diseases classified elsewhere
0.654 0.346 0.000
O36 Maternal care for other known or suspected foetal problems
0.652 0.348 0.000
A49 Bacterial infection of unspecified site
0.652 0.348 0.000
M22.4 Chondromalacia patellae
0.652 0.348 0.000
M54.9 Dorsalgia, unspecified
0.652 0.348 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.651 0.349 0.000
S37 Injury of urinary and pelvic organs
0.651 0.349 0.000
S36 Injury of intra-abdominal organs
0.651 0.349 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.651 0.349 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.651 0.349 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.651 0.349 0.000
S31 Open wound of abdomen, lower back and pelvis
0.651 0.349 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.651 0.349 0.000
G93.0 Cerebral cysts
0.649 0.351 0.000
V20-V29 Motorcycle rider injured in transport accident
0.649 0.351 0.000
J86 Pyothorax
0.649 0.351 0.000
M72 Fibroblastic disorders
0.649 0.351 0.000
H72 Perforation of tympanic membrane
0.649 0.351 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.648 0.351 0.000
J96 Respiratory failure, not elsewhere classified
0.648 0.351 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.648 0.351 0.000
H80-H83 Diseases of inner ear
0.648 0.352 0.000
S67 Crushing injury of wrist and hand
0.648 0.352 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.647 0.353 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.647 0.353 0.000
O42 Premature rupture of membranes
0.646 0.354 0.000
S72 Fracture of femur
0.644 0.356 0.000
M23.9 Internal derangement of knee, unspecified
0.644 0.356 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.644 0.356 0.000
M23.1 Discoid meniscus (congenital)
0.644 0.356 0.000
M23.0 Cystic meniscus
0.644 0.356 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.643 0.357 0.000
M66 Spontaneous rupture of synovium and tendon
0.643 0.357 0.000
F25 Schizoaffective disorders
0.643 0.357 0.000
J39 Other diseases of upper respiratory tract
0.643 0.357 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.642 0.357 0.000
F02 Dementia in other diseases classified elsewhere
0.642 0.357 0.000
F01 Vascular dementia
0.642 0.357 0.000
F09 Unspecified organic or symptomatic mental disorder
0.642 0.357 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.642 0.357 0.000
M79.61 Pain in limb (Shoulder region)
0.642 0.358 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.642 0.358 0.000
M10.4 Other secondary gout
0.642 0.358 0.000
M10.3 Gout due to impairment of renal function
0.642 0.358 0.000
M10.2 Drug-induced gout
0.642 0.358 0.000
M10.1 Lead-induced gout
0.642 0.358 0.000
M10.0 Idiopathic gout
0.642 0.358 0.000
J98.1 Pulmonary collapse
0.641 0.359 0.000
F32 Depressive episode
0.640 0.360 0.000
O72.1 Other immediate postpartum haemorrhage
0.640 0.360 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.640 0.360 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.640 0.360 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.640 0.360 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.639 0.361 0.000
G80 Infantile cerebral palsy
0.639 0.361 0.000
M10.96 Gout, unspecified (Lower leg)
0.639 0.361 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.639 0.361 0.000
G40.5 Special epileptic syndromes
0.639 0.361 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.639 0.361 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.639 0.361 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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