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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2294884
log Bayes Factor = 74.8957
Chromosome 6   position 32,367,259  (GRCh37) Explore rs2294884 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
K50.1 Crohn's disease of large intestine
1.000 0.000 0.000
K50 Crohn's disease [regional enteritis]
1.000 0.000 0.000
K50-K52 Noninfective enteritis and colitis
1.000 0.000 0.000
C44.7 Skin of lower limb, including hip
0.999 0.001 0.000
E10.1 With ketoacidosis
0.000 0.005 0.995
C44.2 Skin of ear and external auricular canal
0.993 0.007 0.000
C44.4 Skin of scalp and neck
0.990 0.010 0.000
K50.9 Crohn's disease, unspecified
0.982 0.018 0.000
E10.3 With ophthalmic complications
0.000 0.020 0.980
K51.4 Pseudopolyposis of colon
0.976 0.024 0.000
K51.2 Ulcerative (chronic) proctitis
0.973 0.027 0.000
Z93.2 Ileostomy status
0.969 0.031 0.000
C44.5 Skin of trunk
0.964 0.036 0.000
K51.8 Other ulcerative colitis
0.950 0.050 0.000
C44.6 Skin of upper limb, including shoulder
0.936 0.064 0.000
C44.0 Skin of lip
0.934 0.066 0.000
E10-E14 Diabetes mellitus
0.000 0.097 0.903
D86.9 Sarcoidosis, unspecified
0.000 0.105 0.895
D86 Sarcoidosis
0.000 0.112 0.888
E16.2 Hypoglycaemia, unspecified
0.000 0.116 0.884
E16 Other disorders of pancreatic internal secretion
0.000 0.117 0.883
C44.1 Skin of eyelid, including canthus
0.882 0.118 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.120 0.880
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.122 0.878
D86.0 Sarcoidosis of lung
0.000 0.132 0.868
E20-E35 Disorders of other endocrine glands
0.000 0.170 0.830
E27.1 Primary adrenocortical insufficiency
0.000 0.172 0.828
E27 Other disorders of adrenal gland
0.000 0.172 0.828
D86.8 Sarcoidosis of other and combined sites
0.000 0.180 0.820
K51.5 Mucosal proctocolitis
0.795 0.205 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.213 0.787
E10.8 With unspecified complications
0.000 0.215 0.784
E10.2 With renal complications
0.000 0.233 0.767
E10.6 With other specified complications
0.000 0.237 0.763
K90 Intestinal malabsorption
0.000 0.238 0.762
E10.0 With coma
0.000 0.241 0.759
E10.4 With neurological complications
0.000 0.247 0.752
K52 Other non-infective gastro-enteritis and colitis
0.727 0.273 0.000
E16.1 Other hypoglycaemia
0.000 0.281 0.719
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.284 0.716
C44.9 Malignant neoplasm of skin, unspecified
0.713 0.287 0.000
E13 Other specified diabetes mellitus
0.000 0.292 0.707
E22 Hyperfunction of pituitary gland
0.000 0.293 0.707
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.304 0.696
K50.8 Other Crohn's disease
0.695 0.305 0.000
E27.2 Addisonian crisis
0.000 0.333 0.667
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.334 0.666
K51.0 Ulcerative (chronic) enterocolitis
0.649 0.351 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.352 0.648
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.352 0.648
E00-E07 Disorders of thyroid gland
0.000 0.362 0.638
D86.3 Sarcoidosis of skin
0.000 0.364 0.636
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.364 0.636
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.367 0.633
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.367 0.633
E16.4 Abnormal secretion of gastrin
0.000 0.367 0.633
E16.3 Increased secretion of glucagon
0.000 0.367 0.633
E24 Cushing's syndrome
0.000 0.367 0.633
E15 Nondiabetic hypoglycaemic coma
0.000 0.369 0.631
E03 Other hypothyroidism
0.000 0.382 0.618
K52.1 Toxic gastro-enteritis and colitis
0.615 0.384 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.385 0.615
K51.3 Ulcerative (chronic) rectosigmoiditis
0.614 0.386 0.000
K52.3 Indeterminate colitis
0.603 0.396 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.603 0.397 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.398 0.602
E20 Hypoparathyroidism
0.000 0.400 0.599
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.405 0.595
E32 Diseases of thymus
0.000 0.405 0.595
E31 Polyglandular dysfunction
0.000 0.405 0.595
E30 Disorders of puberty, not elsewhere classified
0.000 0.405 0.595
E25 Adrenogenital disorders
0.000 0.405 0.595
E27.5 Adrenomedullary hyperfunction
0.000 0.406 0.593
E27.0 Other adrenocortical overactivity
0.000 0.406 0.593
E10.5 With peripheral circulatory complications
0.000 0.417 0.583
E40-E46 Malnutrition
0.000 0.420 0.579
K90.8 Other intestinal malabsorption
0.000 0.422 0.578
E13.9 Without complications
0.000 0.433 0.567
K90.9 Intestinal malabsorption, unspecified
0.000 0.442 0.558
E14 Unspecified diabetes mellitus
0.000 0.448 0.552
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.451 0.549
K90.3 Pancreatic steatorrhoea
0.000 0.454 0.546
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.454 0.546
K90.1 Tropical sprue
0.000 0.454 0.546
K52.8 Other specified non-infective gastro-enteritis and colitis
0.535 0.465 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.468 0.532
E34 Other endocrine disorders
0.000 0.491 0.509
E13.8 With unspecified complications
0.000 0.493 0.507
E13.7 With multiple complications
0.000 0.493 0.507
E13.6 With other specified complications
0.000 0.493 0.507
E13.5 With peripheral circulatory complications
0.000 0.493 0.507
E13.4 With neurological complications
0.000 0.493 0.507
E13.3 With ophthalmic complications
0.000 0.493 0.507
E13.2 With renal complications
0.000 0.493 0.507
E13.1 With ketoacidosis
0.000 0.493 0.507
E13.0 With coma
0.000 0.493 0.507
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.493 0.507
E22.8 Other hyperfunction of pituitary gland
0.000 0.493 0.507
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.506 0.494 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.498 0.501
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.499 0.501
E24.9 Cushing's syndrome, unspecified
0.000 0.509 0.491
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.519 0.481
E22.0 Acromegaly and pituitary gigantism
0.000 0.519 0.481
E29 Testicular dysfunction
0.000 0.520 0.480
E65-E68 Obesity and other hyperalimentation
0.000 0.534 0.466
E12.9 Without complications
0.000 0.535 0.464
E12.8 With unspecified complications
0.000 0.535 0.464
E12.7 With multiple complications
0.000 0.535 0.464
E12.6 With other specified complications
0.000 0.535 0.464
E12.5 With peripheral circulatory complications
0.000 0.535 0.464
E12.4 With neurological complications
0.000 0.535 0.464
E12.3 With ophthalmic complications
0.000 0.535 0.464
E12.2 With renal complications
0.000 0.535 0.464
E12.1 With ketoacidosis
0.000 0.535 0.464
E12.0 With coma
0.000 0.535 0.464
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.542 0.457
E00 Congenital iodine-deficiency syndrome
0.000 0.542 0.457
E24.8 Other Cushing's syndrome
0.000 0.546 0.454
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.546 0.454
E24.3 Ectopic ACTH syndrome
0.000 0.546 0.454
E24.2 Drug-induced Cushing's syndrome
0.000 0.546 0.454
E24.1 Nelson's syndrome
0.000 0.546 0.454
E24.0 Pituitary-dependent Cushing's disease
0.000 0.546 0.454
E03.5 Myxoedema coma
0.000 0.556 0.443
E03.4 Atrophy of thyroid (acquired)
0.000 0.556 0.443
E03.3 Postinfectious hypothyroidism
0.000 0.556 0.443
E03.1 Congenital hypothyroidism without goitre
0.000 0.556 0.443
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.556 0.443
E22.1 Hyperprolactinaemia
0.000 0.558 0.442
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.566 0.434
E20.9 Hypoparathyroidism, unspecified
0.000 0.566 0.434
E03.8 Other specified hypothyroidism
0.000 0.566 0.434
E21.0 Primary hyperparathyroidism
0.000 0.567 0.433
K52.0 Gastro-enteritis and colitis due to radiation
0.431 0.569 0.000
E20.8 Other hypoparathyroidism
0.000 0.570 0.430
E20.1 Pseudohypoparathyroidism
0.000 0.570 0.430
E20.0 Idiopathic hypoparathyroidism
0.000 0.570 0.430
E25.9 Adrenogenital disorder, unspecified
0.000 0.573 0.427
E25.8 Other adrenogenital disorders
0.000 0.573 0.427
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.573 0.427
E30.9 Disorder of puberty, unspecified
0.000 0.573 0.427
E30.8 Other disorders of puberty
0.000 0.573 0.427
E30.1 Precocious puberty
0.000 0.573 0.427
E30.0 Delayed puberty
0.000 0.573 0.427
E31.9 Polyglandular dysfunction, unspecified
0.000 0.573 0.427
E31.8 Other polyglandular dysfunction
0.000 0.573 0.427
E31.1 Polyglandular hyperfunction
0.000 0.573 0.427
E31.0 Autoimmune polyglandular failure
0.000 0.573 0.427
E32.9 Disease of thymus, unspecified
0.000 0.573 0.427
E32.8 Other diseases of thymus
0.000 0.573 0.427
E32.1 Abscess of thymus
0.000 0.573 0.427
E32.0 Persistent hyperplasia of thymus
0.000 0.573 0.427
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.573 0.427
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.573 0.427
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.573 0.427
J45 Asthma
0.000 0.577 0.423
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.584 0.415
E45 Retarded development following protein-energy malnutrition
0.000 0.584 0.415
E43 Unspecified severe protein-energy malnutrition
0.000 0.584 0.415
E42 Marasmic kwashiorkor
0.000 0.584 0.415
E41 Nutritional marasmus
0.000 0.584 0.415
E40 Kwashiorkor
0.000 0.584 0.415
E14.9 Without complications
0.000 0.596 0.404
E28 Ovarian dysfunction
0.000 0.597 0.403
E14.8 With unspecified complications
0.000 0.604 0.396
E14.7 With multiple complications
0.000 0.604 0.396
E14.2 Withrenal complications
0.000 0.604 0.396
E14.1 With ketoacidosis
0.000 0.604 0.396
E14.0 With coma
0.000 0.604 0.396
E14.6 With other specified complications
0.000 0.605 0.394
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.606 0.394
E21.4 Other specified disorders of parathyroid gland
0.000 0.606 0.394
E21.2 Other hyperparathyroidism
0.000 0.606 0.394
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.607 0.393
E27.9 Disorder of adrenal gland, unspecified
0.001 0.612 0.387
E14.3 With ophthalmic complications
0.000 0.615 0.385
E34.0 Carcinoid syndrome
0.000 0.618 0.382
E05.5 Thyroid crisis or storm
0.000 0.619 0.381
E05.4 Thyrotoxicosis factitia
0.000 0.619 0.381
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.619 0.381
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.619 0.381
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.635 0.365
E46 Unspecified protein-energy malnutrition
0.000 0.635 0.365
E34.5 Androgen resistance syndrome
0.000 0.635 0.365
E34.4 Constitutional tall stature
0.000 0.635 0.365
E34.3 Short stature, not elsewhere classified
0.000 0.635 0.365
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.635 0.365
E34.1 Other hypersecretion of intestinal hormones
0.000 0.635 0.365
E23 Hypofunction and other disorders of pituitary gland
0.000 0.637 0.363
E14.5 With peripheral circulatory complications
0.000 0.642 0.358
E14.4 With neurological complications
0.000 0.646 0.354
E26 Hyperaldosteronism
0.001 0.650 0.349
E29.9 Testicular dysfunction, unspecified
0.000 0.656 0.344
E29.8 Other testicular dysfunction
0.000 0.656 0.344
E29.0 Testicular hyperfunction
0.000 0.656 0.344
E05.8 Other thyrotoxicosis
0.000 0.664 0.336
E06 Thyroiditis
0.000 0.664 0.336
E67 Other hyperalimentation
0.000 0.665 0.334
E68 Sequelae of hyperalimentation
0.000 0.665 0.334
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.332 0.668 0.000
E50-E64 Other nutritional deficiencies
0.000 0.668 0.332
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.672 0.328
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.672 0.328
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.672 0.328
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.672 0.328
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.672 0.328
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.672 0.328
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.672 0.328
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.672 0.328
K50.0 Crohn's disease of small intestine
0.321 0.678 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.683 0.316
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.315 0.685 0.000
E66 Obesity
0.000 0.685 0.315
E34.8 Other specified endocrine disorders
0.000 0.686 0.314
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.313 0.687 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.312 0.688 0.000
J45.8 Mixed asthma
0.000 0.697 0.303
J45.1 Nonallergic asthma
0.000 0.697 0.303
J45.0 Predominantly allergic asthma
0.000 0.699 0.301
E44.1 Mild protein-energy malnutrition
0.000 0.702 0.298
E44.0 Moderate protein-energy malnutrition
0.000 0.702 0.298
E28.9 Ovarian dysfunction, unspecified
0.000 0.711 0.289
E28.8 Other ovarian dysfunction
0.000 0.711 0.289
E28.1 Androgen excess
0.000 0.711 0.289
E28.0 Oestrogen excess
0.000 0.711 0.289
Z93 Artificial opening status
0.278 0.722 0.000
E07 Other disorders of thyroid
0.000 0.723 0.276
E23.6 Other disorders of pituitary gland
0.000 0.724 0.276
C82.0 Small cleaved cell, follicular
0.276 0.724 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.727 0.273
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.740 0.260
E23.1 Drug-induced hypopituitarism
0.000 0.740 0.260
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.253 0.747 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.748 0.252
E26.8 Other hyperaldosteronism
0.001 0.749 0.250
E26.1 Secondary hyperaldosteronism
0.001 0.749 0.250
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.249 0.751 0.000
C82.3 Follicular lymphoma grade IIIa
0.245 0.755 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.245 0.755 0.000
C83.3 Large cell (diffuse)
0.244 0.756 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.757 0.243
E28.3 Primary ovarian failure
0.000 0.758 0.241
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.758 0.242
E06.5 Other chronic thyroiditis
0.000 0.759 0.241
E06.4 Drug-induced thyroiditis
0.000 0.759 0.241
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.759 0.241
E06.1 Subacute thyroiditis
0.000 0.759 0.241
E06.0 Acute thyroiditis
0.000 0.759 0.241
E67.8 Other specified hyperalimentation
0.000 0.760 0.240
E67.3 Hypervitaminosis D
0.000 0.760 0.240
E67.2 Megavitamin-B6 syndrome
0.000 0.760 0.240
E67.1 Hypercarotenaemia
0.000 0.760 0.240
E67.0 Hypervitaminosis A
0.000 0.760 0.240
E66.9 Obesity, unspecified
0.000 0.760 0.240
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.762 0.238
E63 Other nutritional deficiencies
0.000 0.762 0.238
E56 Other vitamin deficiencies
0.000 0.762 0.238
E50 Vitamin A deficiency
0.000 0.762 0.238
E60 Dietary zinc deficiency
0.000 0.762 0.238
E59 Dietary selenium deficiency
0.000 0.762 0.238
E54 Ascorbic acid deficiency
0.000 0.762 0.238
E52 Niacin deficiency [pellagra]
0.000 0.762 0.238
Z93.8 Other artificial opening status
0.237 0.763 0.000
E06.9 Thyroiditis, unspecified
0.000 0.767 0.233
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.233 0.767 0.000
C82.2 Large cell, follicular
0.232 0.768 0.000
E29.1 Testicular hypofunction
0.000 0.771 0.228
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.227 0.773 0.000
E11.1 With ketoacidosis
0.000 0.774 0.226
E66.1 Drug-induced obesity
0.000 0.774 0.226
E58 Dietary calcium deficiency
0.000 0.774 0.225
E53 Deficiency of other B group vitamins
0.000 0.775 0.225
C82.6 Cutaneous follicle centre lymphoma
0.224 0.776 0.000
C82.5 Diffuse follicle centre lymphoma
0.224 0.776 0.000
C82.4 Follicular lymphoma grade IIIb
0.224 0.776 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.776 0.223
Z93.6 Other artificial openings of urinary tract status
0.220 0.780 0.000
E51 Thiamine deficiency
0.000 0.782 0.218
C82.1 Mixed small cleaved and large cell, follicular
0.213 0.787 0.000
E65 Localised adiposity
0.001 0.791 0.208
E66.8 Other obesity
0.000 0.792 0.208
E23.2 Diabetes insipidus
0.000 0.793 0.207
C83.1 Small cleaved cell (diffuse)
0.206 0.794 0.000
Z93.9 Artificial opening status, unspecified
0.204 0.796 0.000
C83.2 Mixed small and large cell (diffuse)
0.200 0.799 0.000
E07.1 Dyshormogenetic goitre
0.000 0.801 0.198
E07.0 Hypersecretion of calcitonin
0.000 0.801 0.198
E26.9 Hyperaldosteronism, unspecified
0.002 0.804 0.195
E61 Deficiency of other nutrient elements
0.000 0.805 0.194
C95 Leukaemia of unspecified cell type
0.189 0.811 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.812 0.188
Z93.0 Tracheostomy status
0.188 0.812 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.813 0.186
E66.0 Obesity due to excess calories
0.000 0.815 0.185
Z93.1 Gastrostomy status
0.184 0.816 0.000
E11.2 With renal complications
0.000 0.816 0.184
E07.8 Other specified disorders of thyroid
0.000 0.817 0.182
Z93.4 Other artificial openings of gastro-intestinal tract status
0.182 0.818 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.181 0.819 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.179 0.821 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.179 0.821 0.000
C94 Other leukaemias of specified cell type
0.179 0.821 0.000
C93 Monocytic leukaemia
0.179 0.821 0.000
C86 Other specified types of T/NK-cell lymphoma
0.179 0.821 0.000
C83.6 Undifferentiated (diffuse)
0.175 0.824 0.000
C83.5 Lymphoblastic (diffuse)
0.175 0.824 0.000
C83.4 Immunoblastic (diffuse)
0.175 0.824 0.000
E11.7 With multiple complications
0.000 0.826 0.174
E50.9 Vitamin A deficiency, unspecified
0.000 0.829 0.171
E50.8 Other manifestations of vitamin A deficiency
0.000 0.829 0.171
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.829 0.171
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.829 0.171
E50.5 Vitamin A deficiency with night blindness
0.000 0.829 0.171
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.829 0.171
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.829 0.171
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.829 0.171
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.829 0.171
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.829 0.171
E56.9 Vitamin deficiency, unspecified
0.000 0.829 0.171
E56.8 Deficiency of other vitamins
0.000 0.829 0.171
E56.1 Deficiency of vitamin K
0.000 0.829 0.171
E56.0 Deficiency of vitamin E
0.000 0.829 0.171
E63.9 Nutritional deficiency, unspecified
0.000 0.829 0.171
E63.8 Other specified nutritional deficiencies
0.000 0.829 0.171
E63.1 Imbalance of constituents of food intake
0.000 0.829 0.171
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.829 0.171
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.829 0.171
E64.8 Sequelae of other nutritional deficiencies
0.000 0.829 0.171
E64.3 Sequelae of rickets
0.000 0.829 0.171
E64.2 Sequelae of vitamin C deficiency
0.000 0.829 0.171
E64.1 Sequelae of vitamin A deficiency
0.000 0.829 0.171
E64.0 Sequelae of protein-energy malnutrition
0.000 0.829 0.171
E11.6 With other specified complications
0.000 0.832 0.168
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.167 0.833 0.000
C85.0 Lymphosarcoma
0.167 0.833 0.000
C85.1 B-cell lymphoma, unspecified
0.167 0.833 0.000
E11.8 With unspecified complications
0.000 0.836 0.164
E53.8 Deficiency of other specified B group vitamins
0.000 0.837 0.163
C84 Peripheral and cutaneous T-cell lymphomas
0.162 0.838 0.000
C81 Hodgkin's disease
0.162 0.838 0.000
E53.1 Pyridoxine deficiency
0.000 0.838 0.162
E53.0 Riboflavin deficiency
0.000 0.838 0.162
C83.7 Burkitt's tumour
0.160 0.839 0.000
D82 Immunodeficiency associated with other major defects
0.000 0.839 0.160
D81 Combined immunodeficiencies
0.000 0.839 0.160
E55 Vitamin D deficiency
0.001 0.840 0.160
Z93.3 Colostomy status
0.158 0.842 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.843 0.156
E51.8 Other manifestations of thiamine deficiency
0.000 0.843 0.156
E51.1 Beriberi
0.000 0.843 0.156
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.150 0.850 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.850 0.150
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.850 0.150
C95.0 Acute leukaemia of unspecified cell type
0.149 0.850 0.000
E61.2 Magnesium deficiency
0.000 0.852 0.148
E53.9 Vitamin B deficiency, unspecified
0.000 0.853 0.147
C88 Malignant immunoproliferative diseases
0.147 0.853 0.000
D50-D53 Nutritional anaemias
0.000 0.854 0.146
D83 Common variable immunodeficiency
0.000 0.856 0.144
E11.0 With coma
0.000 0.859 0.140
E61.9 Deficiency of nutrient element, unspecified
0.000 0.860 0.139
E61.8 Deficiency of other specified nutrient elements
0.000 0.860 0.139
E61.7 Deficiency of multiple nutrient elements
0.000 0.860 0.139
E61.6 Vanadium deficiency
0.000 0.860 0.139
E61.5 Molybdenum deficiency
0.000 0.860 0.139
E61.4 Chromium deficiency
0.000 0.860 0.139
E61.3 Manganese deficiency
0.000 0.860 0.139
E61.0 Copper deficiency
0.000 0.860 0.139
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.862 0.138
E51.2 Wernicke's encephalopathy
0.001 0.863 0.136
E06.3 Autoimmune thyroiditis
0.000 0.863 0.136
C95.7 Other leukaemia of unspecified cell type
0.136 0.864 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.136 0.864 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.136 0.864 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.865 0.135
D80 Immunodeficiency with predominantly antibody defects
0.000 0.867 0.133
Z93.5 Cystostomy status
0.133 0.867 0.000
E11.5 With peripheral circulatory complications
0.000 0.867 0.133
D50.9 Iron deficiency anaemia, unspecified
0.000 0.868 0.132
C95.9 Leukaemia, unspecified
0.132 0.868 0.000
C34 Malignant neoplasm of bronchus and lung
0.000 0.869 0.130
D50 Iron deficiency anaemia
0.000 0.869 0.131
E26.0 Primary hyperaldosteronism
0.002 0.870 0.128
M45 Ankylosing spondylitis
0.129 0.871 0.000
D84 Other immunodeficiencies
0.001 0.871 0.128
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.128 0.872 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.128 0.872 0.000
C86.4 Blastic NK-cell lymphoma
0.128 0.872 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.128 0.872 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.128 0.872 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.128 0.872 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.128 0.872 0.000
C93.9 Monocytic leukaemia, unspecified
0.128 0.872 0.000
C93.7 Other monocytic leukaemia
0.128 0.872 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.128 0.872 0.000
C93.2 Subacute monocytic leukaemia
0.128 0.872 0.000
C93.1 Chronic monocytic leukaemia
0.128 0.872 0.000
C93.0 Acute monocytic leukaemia
0.128 0.872 0.000
C94.7 Other specified leukaemias
0.128 0.872 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.128 0.872 0.000
C94.5 Acute myelofibrosis
0.128 0.872 0.000
C94.4 Acute panmyelosis
0.128 0.872 0.000
C94.3 Mast cell leukaemia
0.128 0.872 0.000
C94.2 Acute megakaryoblastic leukaemia
0.128 0.872 0.000
C94.1 Chronic erythraemia
0.128 0.872 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.128 0.872 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.128 0.872 0.000
C96.8 Histiocytic sarcoma
0.128 0.872 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.128 0.872 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.128 0.872 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.128 0.872 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.128 0.872 0.000
C96.3 True histiocytic lymphoma
0.128 0.872 0.000
C96.2 Malignant mast cell tumour
0.128 0.872 0.000
C96.1 Malignant histiocytosis
0.128 0.872 0.000
C96.0 Letterer-Siwe disease
0.128 0.872 0.000
C34.9 Bronchus or lung, unspecified
0.000 0.872 0.128
C90 Multiple myeloma and malignant plasma cell neoplasms
0.126 0.874 0.000
C81.2 Mixed cellularity
0.124 0.875 0.000
C84.0 Mycosis fungoides
0.124 0.876 0.000
C34.3 Lower lobe, bronchus or lung
0.000 0.876 0.124
C34.1 Upper lobe, bronchus or lung
0.000 0.877 0.123
C81.0 Lymphocytic predominance
0.123 0.877 0.000
E23.0 Hypopituitarism
0.001 0.878 0.122
C43 Malignant melanoma of skin
0.122 0.878 0.000
C81.1 Nodular sclerosis
0.121 0.879 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.120 0.880 0.000
C34.0 Main bronchus
0.000 0.882 0.117
C84.9 Mature T/NK-cell lymphoma, unspecified
0.116 0.883 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.116 0.883 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.116 0.883 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.116 0.883 0.000
C84.3 Lymphoepithelioid lymphoma
0.116 0.883 0.000
C84.2 T-zone lymphoma
0.116 0.883 0.000
C84.1 Sezary's diease
0.116 0.883 0.000
C81.7 Other Hodgkin's disease
0.116 0.884 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.116 0.884 0.000
C81.3 Lymphocytic depletion
0.116 0.884 0.000
D81.9 Combined immunodeficiency, unspecified
0.000 0.885 0.115
D81.8 Other combined immunodeficiencies
0.000 0.885 0.115
D81.7 Major histocompatibility complex class II deficiency
0.000 0.885 0.115
D81.6 Major histocompatibility complex class I deficiency
0.000 0.885 0.115
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.885 0.115
D81.4 Nezelof's syndrome
0.000 0.885 0.115
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.885 0.115
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.885 0.115
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.885 0.115
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.885 0.115
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.885 0.115
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.885 0.115
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.885 0.115
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.885 0.115
D82.2 Immunodeficiency with short-limbed stature
0.000 0.885 0.115
D82.1 Di George's syndrome
0.000 0.885 0.115
D82.0 Wiskott-Aldrich syndrome
0.000 0.885 0.115
E55.0 Rickets, active
0.001 0.885 0.115
M45.X2 Ankylosing spondylitis (Cervical region)
0.114 0.886 0.000
E11.3 With ophthalmic complications
0.000 0.886 0.114
C91 Lymphoid leukaemia
0.109 0.890 0.001
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.892 0.108
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.892 0.108
D51.2 Transcobalamin II deficiency
0.000 0.892 0.108
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.892 0.108
C88.9 Malignant immunoproliferative disease, unspecified
0.106 0.894 0.000
C88.7 Other malignant immunoproliferative diseases
0.106 0.894 0.000
C88.3 Immunoproliferative small intestinal disease
0.106 0.894 0.000
C88.2 Gamma heavy chain disease
0.106 0.894 0.000
C88.1 Alpha heavy chain disease
0.106 0.894 0.000
C84.5 Other and unspecified T-cell lymphomas
0.105 0.895 0.000
D83.8 Other common variable immunodeficiencies
0.000 0.896 0.103
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.896 0.103
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.896 0.103
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.896 0.103
D52 Folate deficiency anaemia
0.000 0.896 0.103
C34.2 Middle lobe, bronchus or lung
0.000 0.897 0.103
C84.4 Peripheral T-cell lymphoma
0.103 0.897 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.102 0.897 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.102 0.898 0.000
D53 Other nutritional anaemias
0.000 0.899 0.101
C83.0 Small cell (diffuse)
0.099 0.901 0.000
C92 Myeloid leukaemia
0.099 0.901 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.098 0.902 0.000
C43.4 Malignant melanoma of scalp and neck
0.097 0.903 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.904 0.095
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.904 0.095
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.904 0.095
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.904 0.095
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.904 0.095
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.904 0.095

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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