TreeWAS – Variant ID: rs2299116

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C71.9 Brain, unspecified	0.000	0.495	0.505
C71 Malignant neoplasm of brain	0.000	0.509	0.491
C71.3 Parietal lobe	0.000	0.530	0.470
C71.1 Frontal lobe	0.000	0.551	0.449
C71.8 Overlapping lesion of brain	0.000	0.589	0.411
C71.0 Cerebrum, except lobes and ventricles	0.000	0.596	0.404
C71.4 Occipital lobe	0.000	0.615	0.385
C71.6 Cerebellum	0.000	0.648	0.352
C71.5 Cerebral ventricle	0.000	0.648	0.352
C71.7 Brain stem	0.000	0.656	0.344
C71.2 Temporal lobe	0.000	0.808	0.192
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.890	0.110
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.922	0.078
C70 Malignant neoplasm of meninges	0.000	0.931	0.069
C72.9 Central nervous system, unspecified	0.000	0.944	0.056
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.944	0.056
C72.5 Other and unspecified cranial nerves	0.000	0.944	0.056
C72.4 Acoustic nerve	0.000	0.944	0.056
C72.3 Optic nerve	0.000	0.944	0.056
C72.2 Olfactory nerve	0.000	0.944	0.056
C72.1 Cauda equina	0.000	0.944	0.056
C72.0 Spinal cord	0.000	0.945	0.055
C69 Malignant neoplasm of eye and adnexa	0.000	0.946	0.054
E87.0 Hyperosmolality and hypernatraemia	0.054	0.946	0.000
C70.9 Meninges, unspecified	0.000	0.950	0.049
C70.1 Spinal meninges	0.000	0.950	0.049
C69.9 Eye, unspecified	0.000	0.960	0.040
C70.0 Cerebral meninges	0.000	0.961	0.039
C69.8 Overlapping lesion of eye and adnexa	0.000	0.961	0.039
C69.5 Lachrymal gland and duct	0.000	0.961	0.039
C69.4 Ciliary body	0.000	0.961	0.039
C69.1 Cornea	0.000	0.961	0.039
C69.2 Retina	0.000	0.961	0.039
C69.6 Orbit	0.000	0.962	0.037
C69.0 Conjunctiva	0.000	0.968	0.031
C69.3 Choroid	0.000	0.972	0.028
D68.2 Hereditary deficiency of other clotting factors	0.000	0.981	0.019
O80.9 Single spontaneous delivery, unspecified	0.000	0.982	0.018
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.983	0.017
R44.1 Visual hallucinations	0.011	0.989	0.000
O80 Single spontaneous delivery	0.000	0.990	0.010
G44.2 Tension-type headache	0.008	0.992	0.000
O80.1 Spontaneous breech delivery	0.000	0.993	0.007
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.007	0.993	0.000
O80.8 Other single spontaneous delivery	0.000	0.993	0.007
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.993	0.007
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.993	0.007
M41.96 Scoliosis, unspecified (Lumbar region)	0.007	0.993	0.000
O80.0 Spontaneous vertex delivery	0.000	0.993	0.007
D68 Other coagulation defects	0.000	0.994	0.006
Y84.2 Radiological procedure and radiotherapy	0.000	0.995	0.005
G44 Other headache syndromes	0.005	0.995	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.995	0.005
D68.6 Other Thrombophilia	0.000	0.995	0.005
O80-O84 Delivery	0.000	0.995	0.005
M18 Arthrosis of first carpometacarpal joint	0.005	0.995	0.000
G44.1 Vascular headache, not elsewhere classified	0.005	0.995	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.995	0.005
G44.8 Other specified headache syndromes	0.005	0.995	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.005	0.995	0.000
D68.5 Primary Thrombophilia	0.000	0.996	0.004
D68.0 Von Willebrand's disease	0.000	0.996	0.004
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.996	0.004
G44.3 Chronic posttraumatic headache	0.004	0.996	0.000
O82 Single delivery by Caesarean section	0.000	0.996	0.004
R44 Other symptoms and signs involving general sensations and perceptions	0.004	0.996	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.004	0.996	0.000
E55.9 Vitamin D deficiency, unspecified	0.004	0.996	0.000
Z94.8 Other transplanted organ and tissue status	0.004	0.996	0.000
O82.0 Delivery by elective Caesarean section	0.000	0.996	0.004
O84 Multiple delivery	0.000	0.996	0.004
O83 Other assisted single delivery	0.000	0.996	0.004
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.004	0.996	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.004	0.996	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.004	0.996	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.004	0.996	0.000
O82.1 Delivery by emergency Caesarean section	0.000	0.996	0.004
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.003	0.996	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.003	0.996	0.000
M41.9 Scoliosis, unspecified	0.003	0.996	0.000
R44.2 Other hallucinations	0.003	0.997	0.000
G12.2 Motor neuron disease	0.000	0.997	0.003
Y83.3 Surgical operation with formation of external stoma	0.000	0.997	0.003
O81 Single delivery by forceps and vacuum extractor	0.000	0.997	0.003
H02.5 Other disorders affecting eyelid function	0.003	0.997	0.000
O82.8 Other single delivery by Caesarean section	0.000	0.997	0.003
O82.2 Delivery by Caesarean hysterectomy	0.000	0.997	0.003
D68.9 Coagulation defect, unspecified	0.000	0.997	0.003
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
Z63.4 Disappearance and death of family member	0.003	0.997	0.000
G44.0 Cluster headache syndrome	0.003	0.997	0.000
O81.4 Vacuum extractor delivery	0.000	0.997	0.003
O83.9 Assisted single delivery, unspecified	0.000	0.997	0.003
O83.8 Other specified assisted single delivery	0.000	0.997	0.003
O83.4 Destructive operation for delivery	0.000	0.997	0.003
O83.3 Delivery of viable foetus in abdominal pregnancy	0.000	0.997	0.003
O83.2 Other manipulation-assisted delivery	0.000	0.997	0.003
O83.1 Other assisted breech delivery	0.000	0.997	0.003
O83.0 Breech extraction	0.000	0.997	0.003
O84.9 Multiple delivery, unspecified	0.000	0.997	0.003
O84.8 Other multiple delivery	0.000	0.997	0.003
O84.2 Multiple delivery, all by Caesarean section	0.000	0.997	0.003
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.000	0.997	0.003
O84.0 Multiple delivery, all spontaneous	0.000	0.997	0.003
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.003	0.997	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.003	0.997	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.997	0.003
Q54.9 Hypospadias, unspecified	0.003	0.997	0.000
O82.9 Delivery by Caesarean section, unspecified	0.000	0.997	0.003
M67.8 Other specified disorders of synovium and tendon	0.003	0.997	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
J31.2 Chronic pharyngitis	0.000	0.997	0.003
M41.92 Scoliosis, unspecified (Cervical region)	0.003	0.997	0.000
A63.0 Anogenital (venereal) warts	0.003	0.997	0.000
R44.0 Auditory hallucinations	0.003	0.997	0.000
C77.3 Axillary and upper limb lymph nodes	0.003	0.997	0.000
S22.20 Fracture of sternum (closed)	0.003	0.997	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.003	0.997	0.000
K65.9 Peritonitis, unspecified	0.000	0.997	0.003
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.997	0.002
O81.2 Mid-cavity forceps with rotation	0.000	0.997	0.002
O81.1 Mid-cavity forceps delivery	0.000	0.997	0.002
C45.7 Mesothelioma of other sites	0.003	0.997	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.997	0.003
H49.0 Third [oculomotor] nerve palsy	0.000	0.997	0.003
M25.71 Osteophyte (Shoulder region)	0.003	0.997	0.000
Y54.3 Benzothiadiazine derivatives	0.003	0.997	0.000
Z73.3 Stress, not elsewhere classified	0.000	0.997	0.003
S72.40 Fracture of lower end of femur (closed)	0.000	0.997	0.002
M87.9 Osteonecrosis, unspecified	0.000	0.998	0.002
O81.3 Other and unspecified forceps delivery	0.000	0.998	0.002
O81.0 Low forceps delivery	0.000	0.998	0.002
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.002	0.998	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.998	0.002
M25.77 Osteophyte (Ankle and foot)	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.000	0.998	0.002
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
C44.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
D16.1 Short bones of upper limb	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.000	0.998	0.002
G12 Spinal muscular atrophy and related syndromes	0.000	0.998	0.002
Q54 Hypospadias	0.002	0.998	0.000
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.002	0.998	0.000
D16.3 Short bones of lower limb	0.002	0.998	0.000
C45 Mesothelioma	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
C81.1 Nodular sclerosis	0.002	0.998	0.000
I25.2 Old myocardial infarction	0.002	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.002	0.998	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.998	0.002
O21.2 Late vomiting of pregnancy	0.000	0.998	0.002
X67.9 Unspecified place	0.002	0.998	0.000
M24.1 Other articular cartilage disorders	0.000	0.998	0.002
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.998	0.002
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.998	0.002
M41 Scoliosis	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.998	0.002
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.998	0.002
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.998	0.002
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.998	0.002
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.998	0.002
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.998	0.002
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
S72.41 Fracture of lower end of femur (open)	0.000	0.998	0.002
K65.0 Acute peritonitis	0.000	0.998	0.002
S72.4 Fracture of lower end of femur	0.000	0.998	0.002
C45.0 Mesothelioma of pleura	0.002	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.998	0.002
E55 Vitamin D deficiency	0.002	0.998	0.000
Q54.1 Hypospadias, penile	0.002	0.998	0.000
J31.1 Chronic nasopharyngitis	0.000	0.998	0.002
J93.1 Other spontaneous pneumothorax	0.000	0.998	0.002
O21 Excessive vomiting in pregnancy	0.000	0.998	0.002
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.002	0.998	0.000
X68.9 Unspecified place	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
Q54.8 Other hypospadias	0.002	0.998	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.998	0.002
M25.78 Osteophyte (Other)	0.002	0.998	0.000
G12.9 Spinal muscular atrophy, unspecified	0.000	0.998	0.002
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.998	0.002
G12.1 Other inherited spinal muscular atrophy	0.000	0.998	0.002
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.998	0.002
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
L73.9 Follicular disorder, unspecified	0.002	0.998	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.998	0.002
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.000	0.998	0.002
C45.2 Mesothelioma of pericardium	0.002	0.998	0.000
C45.1 Mesothelioma of peritoneum	0.002	0.998	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.002	0.998	0.000
I44.6 Other and unspecified fascicular block	0.002	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.998	0.002
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.998	0.002
M41.5 Other secondary scoliosis	0.002	0.998	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.998	0.002
M24.18 Other articular cartilage disorders (Other)	0.000	0.998	0.002
M24.14 Other articular cartilage disorders (Hand)	0.000	0.998	0.002
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.998	0.002
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.998	0.002
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
M51.9 Intervertebral disk disorder, unspecified	0.002	0.998	0.000
N90.7 Vulvar cyst	0.000	0.998	0.002
M41.4 Neuromuscular scoliosis	0.002	0.998	0.000
M41.3 Thoracogenic scoliosis	0.002	0.998	0.000
M41.2 Other idiopathic scoliosis	0.002	0.998	0.000
M41.1 Juvenile idiopathic scoliosis	0.002	0.998	0.000
M41.0 Infantile idiopathic scoliosis	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
M41.8 Other forms of scoliosis	0.002	0.998	0.000
T86.0 Bone-marrow transplant rejection	0.002	0.998	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.002	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.002	0.998	0.000
E55.0 Rickets, active	0.001	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.998	0.002
S81.9 Open wound of lower leg, part unspecified	0.000	0.998	0.002
M25.87 Other specified joint disorders (Ankle and foot)	0.002	0.998	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.001	0.998	0.000
I25.3 Aneurysm of heart	0.000	0.998	0.002
O21.8 Other vomiting complicating pregnancy	0.000	0.998	0.001
R46.8 Other symptoms and signs involving appearance and behaviour	0.002	0.998	0.000
K65 Peritonitis	0.000	0.998	0.002
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.002
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.998	0.002
M25.7 Osteophyte	0.002	0.998	0.000
M51.8 Other specified intervertebral disk disorders	0.002	0.998	0.000
W06.0 Home	0.002	0.998	0.000
M15.1 Heberden's nodes (with arthropathy)	0.002	0.998	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.002	0.998	0.000
Z63 Other problems related to primary support group, including family circumstances	0.002	0.998	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.001	0.998	0.000
Z63.5 Disruption of family by separation and divorce	0.002	0.998	0.000
D16 Benign neoplasm of bone and articular cartilage	0.002	0.998	0.000
M15.99 Polyosteoarthritis, unspecified	0.001	0.998	0.000
M41.59 Other secondary scoliosis (Site unspecified)	0.001	0.998	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.54 Other secondary scoliosis (Thoracic region)	0.001	0.998	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.001	0.998	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.001	0.998	0.000
D16.9 Bone and articular cartilage, unspecified	0.001	0.998	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.002	0.998	0.000
F31.8 Other bipolar affective disorders	0.000	0.998	0.001
M06.0 Seronegative rheumatoid arthritis	0.002	0.998	0.000
Z63.6 Dependent relative needing care at home	0.001	0.998	0.000
F31 Bipolar affective disorder	0.000	0.998	0.002
F10.3 Withdrawal state	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.002	0.998	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.001	0.998	0.000
M25.73 Osteophyte (Forearm)	0.001	0.998	0.000
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.001	0.998	0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)	0.001	0.998	0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)	0.001	0.998	0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)	0.001	0.998	0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)	0.001	0.998	0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)	0.001	0.998	0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.29 Other idiopathic scoliosis (Site unspecified)	0.001	0.998	0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.26 Other idiopathic scoliosis (Lumbar region)	0.001	0.998	0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.24 Other idiopathic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.22 Other idiopathic scoliosis (Cervical region)	0.001	0.998	0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.39 Thoracogenic scoliosis-Site unspe	0.001	0.998	0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ	0.001	0.998	0.000
M41.37 Thoracogenic scoliosis-Lumbosacral	0.001	0.998	0.000
M41.36 Thoracogenic scoliosis-Lumbar	0.001	0.998	0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.34 Thoracogenic scoliosis (Thoracic region)	0.001	0.998	0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.32 Thoracogenic scoliosis-Cervical	0.001	0.998	0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl	0.001	0.998	0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M41.49 Neuromuscular scoliosis (Site unspecified)	0.001	0.998	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.46 Neuromuscular scoliosis (Lumbar region)	0.001	0.998	0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.44 Neuromuscular scoliosis (Thoracic region)	0.001	0.998	0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.42 Neuromuscular scoliosis (Cervical region)	0.001	0.998	0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.001	0.998	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.001	0.998	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.001	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.998	0.001
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.998	0.001
M15.9 Polyarthrosis, unspecified	0.001	0.998	0.000
O21.9 Vomiting of pregnancy, unspecified	0.000	0.998	0.001
Z50.5 Speech therapy	0.000	0.998	0.001
M41.89 Other forms of scoliosis (Site unspecified)	0.001	0.999	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.001	0.999	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.001	0.999	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.001	0.999	0.000
A63.8 Other specified predominantly sexually transmitted diseases	0.001	0.999	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.999	0.001
S72.2 Subtrochanteric fracture	0.000	0.999	0.001
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.001	0.999	0.000
M87.2 Osteonecrosis due to previous trauma	0.000	0.999	0.001
O70.2 Third degree perineal laceration during delivery	0.000	0.999	0.001
C49 Malignant neoplasm of other connective and soft tissue	0.001	0.999	0.000
M15 Polyarthrosis	0.001	0.999	0.000
L73.8 Other specified follicular disorders	0.001	0.999	0.000
M25.74 Osteophyte (Hand)	0.001	0.999	0.000
M25.70 Osteophyte (Multiple sites)	0.001	0.999	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.001	0.999	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.001	0.999	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.999	0.001
K08.3 Retained dental root	0.000	0.999	0.001
Z63.9 Problem related to primary support group, unspecified	0.001	0.999	0.000
Z63.3 Absence of family member	0.001	0.999	0.000
Z63.2 Inadequate family support	0.001	0.999	0.000
Z63.1 Problems in relationship with parents and in-laws	0.001	0.999	0.000
M87 Osteonecrosis	0.000	0.999	0.001
D16.8 Pelvic bones, sacrum and coccyx	0.001	0.999	0.000
D16.7 Ribs, sternum and clavicle	0.001	0.999	0.000
D16.6 Vertebral column	0.001	0.999	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.999	0.001
I05.9 Mitral valve disease, unspecified	0.001	0.999	0.000
D86 Sarcoidosis	0.000	0.999	0.001
M06.08 Seronegative rheumatoid arthritis (Other)	0.001	0.999	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.001	0.999	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.001	0.999	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.001	0.999	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.001	0.999	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.001	0.999	0.000
M25.79 Osteophyte (Site unspecified)	0.001	0.999	0.000
J85.2 Abscess of lung without pneumonia	0.000	0.999	0.001
N41.0 Acute prostatitis	0.000	0.999	0.001
S22.2 Fracture of sternum	0.001	0.999	0.000
D16.4 Bones of skull and face	0.001	0.999	0.000
M15.0 Primary generalised (osteo)arthrosis	0.001	0.999	0.000
M51.3 Other specified intervertebral disk degeneration	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.999	0.001
M16.0 Primary coxarthrosis, bilateral	0.000	0.999	0.001
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.999	0.001
Y54.4 Loop [high-ceiling] diuretics	0.001	0.999	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.999	0.001
Z38.0 Singleton, born in hospital	0.000	0.999	0.001
Z63.8 Other specified problems related to primary support group	0.001	0.999	0.000
S72.21 Subtrochanteric fracture (open)	0.000	0.999	0.001
I47.9 Paroxysmal tachycardia, unspecified	0.001	0.999	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.000	0.999	0.001
M87.28 Osteonecrosis due to previous trauma (Other)	0.000	0.999	0.001
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.999	0.001
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.000	0.999	0.001
M87.24 Osteonecrosis due to previous trauma (Hand)	0.000	0.999	0.001
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.000	0.999	0.001
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.000	0.999	0.001
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.000	0.999	0.001
B44.1 Other pulmonary aspergillosis	0.000	0.999	0.001
C49.8 Overlapping lesion of connective and soft tissue	0.001	0.999	0.000
D16.0 Scapula and long bones of upper limb	0.001	0.999	0.000
D86.3 Sarcoidosis of skin	0.000	0.999	0.001
F01.9 Vascular dementia, unspecified	0.001	0.999	0.000
F06.7 Mild cognitive disorder	0.001	0.999	0.000
F43.1 Posttraumatic stress disorder	0.001	0.999	0.000
M15.3 Secondary multiple arthrosis	0.001	0.999	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.999	0.001
O28 Abnormal findings on antenatal screening of mother	0.000	0.999	0.001
M10.90 Gout, unspecified (Multiple sites)	0.001	0.999	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.001	0.999	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.999	0.001
D86.1 Sarcoidosis of lymph nodes	0.000	0.999	0.001
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.999	0.001
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.999	0.001
Z63.7 Other stressful life events affecting family and household	0.001	0.999	0.000
M10.96 Gout, unspecified (Lower leg)	0.001	0.999	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.001	0.999	0.001
M15.8 Other polyarthrosis	0.001	0.999	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.999	0.001
M87.3 Other secondary osteonecrosis	0.000	0.999	0.001
M87.1 Osteonecrosis due to drugs	0.000	0.999	0.001
M87.0 Idiopathic aseptic necrosis of bone	0.000	0.999	0.001
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
M94.26 Chondromalacia (Lower leg)	0.000	0.999	0.001
S22.21 Fracture of sternum (open)	0.001	0.999	0.000
M87.8 Other osteonecrosis	0.000	0.999	0.001
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.999	0.001
M25.56 Pain in joint (Lower leg)	0.001	0.999	0.000
C49.5 Connective and soft tissue of pelvis	0.001	0.999	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.001	0.999	0.000
H44.8 Other disorders of globe	0.001	0.999	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.001	0.999	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.999	0.001
C49.3 Connective and soft tissue of thorax	0.001	0.999	0.000
D16.5 Lower jaw bone	0.001	0.999	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.001	0.999	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.001	0.999	0.000
D33.3 Cranial nerves	0.001	0.999	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.999	0.001
G11 Hereditary ataxia	0.000	0.999	0.001
M10.93 Gout, unspecified (Forearm)	0.001	0.999	0.000
D16.2 Long bones of lower limb	0.001	0.999	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.999	0.001
G11.9 Hereditary ataxia, unspecified	0.000	0.999	0.001
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.999	0.001
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.999	0.001
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.999	0.001
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.999	0.001
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.999	0.001
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.999	0.001
R09.2 Respiratory arrest	0.000	0.999	0.001
Y46.4 Iminostilbenes	0.001	0.999	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.001	0.999	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.999	0.001
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.999	0.001
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.999	0.001
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.999	0.001
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.000	0.999	0.001
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.000	0.999	0.001
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.000	0.999	0.001
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.000	0.999	0.001
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.000	0.999	0.001
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.000	0.999	0.001
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.000	0.999	0.001
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.000	0.999	0.001
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.000	0.999	0.001
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.000	0.999	0.001
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.000	0.999	0.001
M87.18 Osteonecrosis due to drugs (Other)	0.000	0.999	0.001
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.000	0.999	0.001
M87.16 Osteonecrosis due to drugs (Lower leg)	0.000	0.999	0.001
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.000	0.999	0.001
M87.14 Osteonecrosis due to drugs (Hand)	0.000	0.999	0.001
M87.13 Osteonecrosis due to drugs (Forearm)	0.000	0.999	0.001
M87.12 Osteonecrosis due to drugs (Upper arm)	0.000	0.999	0.001
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.000	0.999	0.001
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.000	0.999	0.001
M87.39 Other secondary osteonecrosis (Site unspecified)	0.000	0.999	0.001
M87.38 Other secondary osteonecrosis (Other)	0.000	0.999	0.001
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.000	0.999	0.001
M87.36 Other secondary osteonecrosis (Lower leg)	0.000	0.999	0.001
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.000	0.999	0.001
M87.34 Other secondary osteonecrosis (Hand)	0.000	0.999	0.001
M87.33 Other secondary osteonecrosis (Forearm)	0.000	0.999	0.001
M87.32 Other secondary osteonecrosis (Upper arm)	0.000	0.999	0.001
M87.31 Other secondary osteonecrosis (Shoulder region)	0.000	0.999	0.001
M87.30 Other secondary osteonecrosis (Multiple sites)	0.000	0.999	0.001
M87.89 Other osteonecrosis (Site unspecified)	0.000	0.999	0.001
M87.88 Other osteonecrosis (Other)	0.000	0.999	0.001
M87.87 Other osteonecrosis (Ankle and foot)	0.000	0.999	0.001
M87.86 Other osteonecrosis (Lower leg)	0.000	0.999	0.001
M87.84 Other osteonecrosis (Hand)	0.000	0.999	0.001
M87.83 Other osteonecrosis (Forearm)	0.000	0.999	0.001
M87.82 Other osteonecrosis (Upper arm)	0.000	0.999	0.001
M87.81 Other osteonecrosis (Shoulder region)	0.000	0.999	0.001
M87.80 Other osteonecrosis (Multiple sites)	0.000	0.999	0.001
B44.9 Aspergillosis, unspecified	0.000	0.999	0.001
H61.3 Acquired stenosis of external ear canal	0.001	0.999	0.000
M15.4 Erosive (osteo)arthrosis	0.001	0.999	0.000
Z94.4 Liver transplant status	0.001	0.999	0.000
G10 Huntington's disease	0.000	0.999	0.001
M10.92 Gout, unspecified (Upper arm)	0.001	0.999	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.999	0.001
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.001	0.999	0.000
C90.2 Plasmacytoma, extramedullary	0.001	0.999	0.000
G11.1 Early-onset cerebellar ataxia	0.000	0.999	0.001
T02.4 Fractures involving multiple regions of both upper limbs	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations