TreeWAS – Variant ID: rs2307121

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M25.77 Osteophyte (Ankle and foot)	0.000	0.917	0.083
M25.76 Osteophyte (Lower leg)	0.000	0.947	0.053
M25.7 Osteophyte	0.000	0.948	0.052
M25.71 Osteophyte (Shoulder region)	0.000	0.951	0.049
M25.79 Osteophyte (Site unspecified)	0.000	0.956	0.043
M25.73 Osteophyte (Forearm)	0.000	0.962	0.038
M25.70 Osteophyte (Multiple sites)	0.000	0.963	0.037
M25.78 Osteophyte (Other)	0.000	0.981	0.019
M25.72 Osteophyte (Upper arm)	0.001	0.983	0.016
E04.2 Non-toxic multinodular goitre	0.017	0.983	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.984	0.016
O36.5 Maternal care for poor foetal growth	0.000	0.984	0.016
D73.0 Hyposplenism	0.000	0.984	0.016
E04.1 Non-toxic single thyroid nodule	0.015	0.985	0.000
O36 Maternal care for other known or suspected foetal problems	0.000	0.985	0.015
O36.8 Maternal care for other specified foetal problems	0.000	0.985	0.015
D73 Diseases of spleen	0.000	0.985	0.015
D73.5 Infarction of spleen	0.000	0.985	0.014
E04 Other non-toxic goitre	0.014	0.986	0.000
D73.1 Hypersplenism	0.000	0.988	0.012
O36.1 Maternal care for other isoimmunisation	0.000	0.988	0.012
D72 Other disorders of white blood cells	0.000	0.988	0.012
D72.8 Other specified disorders of white blood cells	0.000	0.988	0.012
D72.1 Eosinophilia	0.000	0.988	0.012
O36.9 Maternal care for foetal problem, unspecified	0.000	0.989	0.011
D73.3 Abscess of spleen	0.000	0.989	0.011
O36.2 Maternal care for hydrops foetalis	0.000	0.989	0.011
D73.2 Chronic congestive splenomegaly	0.000	0.989	0.011
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.989	0.011
M25.74 Osteophyte (Hand)	0.000	0.989	0.010
E04.0 Non-toxic diffuse goitre	0.011	0.989	0.000
E04.8 Other specified non-toxic goitre	0.010	0.990	0.000
O36.4 Maternal care for intra-uterine death	0.000	0.990	0.010
D73.9 Disease of spleen, unspecified	0.000	0.990	0.010
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.990	0.010
D73.8 Other diseases of spleen	0.000	0.990	0.010
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.990	0.010
O36.6 Maternal care for excessive foetal growth	0.000	0.991	0.009
D72.9 Disorder of white blood cells, unspecified	0.000	0.991	0.009
D72.0 Genetic anomalies of leukocytes	0.000	0.991	0.009
D73.4 Cyst of spleen	0.000	0.991	0.009
E05.0 Thyrotoxicosis with diffuse goitre	0.009	0.991	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.992	0.008
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.992	0.008
D74 Methaemoglobinaemia	0.000	0.992	0.008
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.992	0.008
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.992	0.008
L85.9 Epidermal thickening, unspecified	0.000	0.992	0.008
M25.75 Osteophyte (Pelvic region and thigh)	0.001	0.992	0.007
D75 Other diseases of blood and blood-forming organs	0.000	0.992	0.008
E05 Thyrotoxicosis [hyperthyroidism]	0.008	0.992	0.000
E00-E07 Disorders of thyroid gland	0.007	0.993	0.000
D75.1 Secondary polycythaemia	0.000	0.993	0.007
E06 Thyroiditis	0.007	0.993	0.000
E06.3 Autoimmune thyroiditis	0.007	0.993	0.000
D76.3 Other histiocytosis syndromes	0.000	0.993	0.006
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.007	0.993	0.000
L85 Other epidermal thickening	0.000	0.994	0.006
M16.0 Primary coxarthrosis, bilateral	0.006	0.994	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.994	0.006
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.994	0.006
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.994	0.006
L85.8 Other specified epidermal thickening	0.000	0.994	0.006
D74.9 Methaemoglobinaemia, unspecified	0.000	0.994	0.006
D74.8 Other methaemoglobinaemias	0.000	0.994	0.006
D74.0 Congenital methaemoglobinaemia	0.000	0.994	0.006
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.000	0.994	0.006
E06.5 Other chronic thyroiditis	0.006	0.994	0.000
E05.5 Thyroid crisis or storm	0.006	0.994	0.000
E05.4 Thyrotoxicosis factitia	0.006	0.994	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.006	0.994	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.006	0.994	0.000
D75.0 Familial erythrocytosis	0.000	0.994	0.005
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.005	0.994	0.000
E00 Congenital iodine-deficiency syndrome	0.005	0.994	0.000
E05.8 Other thyrotoxicosis	0.005	0.995	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.995	0.005
E06.4 Drug-induced thyroiditis	0.005	0.995	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.005	0.995	0.000
E06.1 Subacute thyroiditis	0.005	0.995	0.000
E06.0 Acute thyroiditis	0.005	0.995	0.000
D75.2 Essential thrombocytosis	0.000	0.995	0.005
C44.2 Skin of ear and external auricular canal	0.000	0.995	0.005
L85.3 Xerosis cutis	0.000	0.995	0.005
L85.2 Keratosis punctata (palmaris et plantaris)	0.000	0.995	0.005
L85.0 Acquired ichthyosis	0.000	0.995	0.005
E02 Subclinical iodine-deficiency hypothyroidism	0.005	0.995	0.000
H11.3 Conjunctival haemorrhage	0.000	0.995	0.005
D07.1 Vulva	0.000	0.995	0.005
E06.9 Thyroiditis, unspecified	0.004	0.996	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.996	0.004
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.004	0.996	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.004	0.996	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.004	0.996	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.004	0.996	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.004	0.996	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.004	0.996	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.004	0.996	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.004	0.996	0.000
O64.1 Obstructed labour due to breech presentation	0.004	0.996	0.000
E05.9 Thyrotoxicosis, unspecified	0.004	0.996	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.996	0.004
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.996	0.004
N42.1 Congestion and haemorrhage of prostate	0.004	0.996	0.000
D53.9 Nutritional anaemia, unspecified	0.000	0.996	0.004
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.996	0.004
H11.9 Disorder of conjunctiva, unspecified	0.000	0.996	0.004
N32.9 Bladder disorder, unspecified	0.004	0.996	0.000
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
D53 Other nutritional anaemias	0.000	0.996	0.004
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.996	0.004
E07 Other disorders of thyroid	0.003	0.996	0.000
H11 Other disorders of conjunctiva	0.000	0.996	0.003
D50-D53 Nutritional anaemias	0.000	0.997	0.003
D51.2 Transcobalamin II deficiency	0.000	0.997	0.003
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.997	0.003
H02.3 Blepharochalasis	0.000	0.997	0.003
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.997	0.003
H11.8 Other specified disorders of conjunctiva	0.000	0.997	0.003
H35.0 Background retinopathy and retinal vascular changes	0.003	0.997	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.997	0.003
E04.9 Non-toxic goitre, unspecified	0.003	0.997	0.000
D52 Folate deficiency anaemia	0.000	0.997	0.003
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.997	0.003
D52.9 Folate deficiency anaemia, unspecified	0.000	0.997	0.003
H10.9 Conjunctivitis, unspecified	0.000	0.997	0.003
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.997	0.003
M79.19 Myalgia (Site unspecified)	0.000	0.997	0.003
F41.9 Anxiety disorder, unspecified	0.000	0.997	0.003
H11.1 Conjunctival degenerations and deposits	0.000	0.997	0.003
D53.8 Other specified nutritional anaemias	0.000	0.997	0.003
D53.2 Scorbutic anaemia	0.000	0.997	0.003
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.997	0.003
D53.0 Protein deficiency anaemia	0.000	0.997	0.003
C43.5 Malignant melanoma of trunk	0.000	0.997	0.003
E07.1 Dyshormogenetic goitre	0.003	0.997	0.000
E07.0 Hypersecretion of calcitonin	0.003	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.997	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.997	0.003
Q54.9 Hypospadias, unspecified	0.003	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.000	0.997	0.003
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.997	0.003
E07.8 Other specified disorders of thyroid	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
S22.20 Fracture of sternum (closed)	0.003	0.997	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.997	0.003
D52.8 Other folate deficiency anaemias	0.000	0.997	0.002
D52.1 Drug-induced folate deficiency anaemia	0.000	0.997	0.002
D52.0 Dietary folate deficiency anaemia	0.000	0.997	0.002
C80.9 Malignant neoplasm, unspecified	0.003	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.997	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.997	0.003
L90.0 Lichen sclerosus et atrophicus	0.000	0.997	0.003
D07.4 Penis	0.000	0.998	0.002
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.000	0.998	0.002
D07.2 Vagina	0.000	0.998	0.002
H10 Conjunctivitis	0.000	0.998	0.002
K11.8 Other diseases of salivary glands	0.002	0.998	0.000
D86 Sarcoidosis	0.002	0.998	0.000
I33.0 Acute and subacute infective endocarditis	0.002	0.998	0.000
Q51.2 Other doubling of uterus	0.002	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.998	0.002
D07.6 Other and unspecified male genital organs	0.000	0.998	0.002
D07.3 Other and unspecified female genital organs	0.000	0.998	0.002
D07.0 Endometrium	0.000	0.998	0.002
S02.2 Fracture of nasal bones	0.000	0.998	0.002
K08.8 Other specified disorders of teeth and supporting structures	0.002	0.998	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.998	0.002
D69.6 Thrombocytopenia, unspecified	0.000	0.998	0.002
D07.5 Prostate	0.000	0.998	0.002
H11.2 Conjunctival scars	0.000	0.998	0.002
Q54.8 Other hypospadias	0.002	0.998	0.000
H10-H13 Disorders of conjunctiva	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
D69.4 Other primary thrombocytopenia	0.000	0.998	0.002
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.000	0.998	0.002
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.998	0.002
E03 Other hypothyroidism	0.002	0.998	0.000
I99 Other and unspecified disorders of circulatory system	0.000	0.998	0.002
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.998	0.002
G55.2 Nerve root and plexus compressions in spondylosis	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
Q54.1 Hypospadias, penile	0.002	0.998	0.000
D02.0 Larynx	0.000	0.998	0.002
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.998	0.002
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.002	0.998	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.998	0.002
N36.0 Urethral fistula	0.002	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
H11.0 Pterygium	0.000	0.998	0.002
M07.38 Other psoriatic arthropathies (Other)	0.000	0.998	0.002
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.998	0.002
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.998	0.002
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.998	0.002
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
H10.8 Other conjunctivitis	0.000	0.998	0.002
H10.5 Blepharoconjunctivitis	0.000	0.998	0.002
H10.2 Other acute conjunctivitis	0.000	0.998	0.002
H10.1 Acute atopic conjunctivitis	0.000	0.998	0.002
H10.0 Mucopurulent conjunctivitis	0.000	0.998	0.002
N71.1 Chronic inflammatory disease of uterus	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
D69.5 Secondary thrombocytopenia	0.000	0.998	0.002
H06.2 Dysthyroid exophthalmos	0.002	0.998	0.000
I45.5 Other specified heart block	0.002	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.002	0.998	0.000
R90.0 Intracranial space-occupying lesion	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
C53.9 Cervix uteri, unspecified	0.002	0.998	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.998	0.002
D69.8 Other specified haemorrhagic conditions	0.000	0.998	0.002
D69.1 Qualitative platelet defects	0.000	0.998	0.002
J32.0 Chronic maxillary sinusitis	0.000	0.998	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.998	0.002
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.998	0.002
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
H10.4 Chronic conjunctivitis	0.000	0.998	0.002
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.002	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.998	0.000
E80.6 Other disorders of bilirubin metabolism	0.002	0.998	0.000
H10.3 Acute conjunctivitis, unspecified	0.000	0.998	0.002
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.002
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.998	0.002
E03.5 Myxoedema coma	0.002	0.998	0.000
E03.4 Atrophy of thyroid (acquired)	0.002	0.998	0.000
E03.3 Postinfectious hypothyroidism	0.002	0.998	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.002	0.998	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.998	0.002
H13 Disorders of conjunctiva in diseases classified elsewhere	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.001	0.998	0.001
E03.1 Congenital hypothyroidism without goitre	0.002	0.998	0.000
Z46.8 Fitting and adjustment of other specified devices	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.000	0.998	0.002
Q52.1 Doubling of vagina	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.002
Z49.0 Preparatory care for dialysis	0.002	0.998	0.000
I33.9 Acute endocarditis, unspecified	0.002	0.998	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.002
T50.5 Appetite depressants	0.000	0.998	0.002
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.002
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.002
Q52.5 Fusion of labia	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.001	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.001	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.001	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.001	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.001	0.998	0.000
Q52.3 Imperforate hymen	0.001	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.001	0.998	0.000
Q52.0 Congenital absence of vagina	0.001	0.998	0.000
D55-D59 Haemolytic anaemias	0.000	0.998	0.001
C26.0 Intestinal tract, part unspecified	0.000	0.998	0.002
G94.2 Hydrocephalus in other diseases classified elsewhere	0.002	0.998	0.000
I45.3 Trifascicular block	0.002	0.998	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.998	0.000
T50.8 Diagnostic agents	0.000	0.998	0.001
D67 Hereditary factor IX deficiency	0.000	0.998	0.001
J04.0 Acute laryngitis	0.000	0.998	0.002
J38.0 Paralysis of vocal cords and larynx	0.000	0.998	0.002
O70.9 Perineal laceration during delivery, unspecified	0.002	0.998	0.000
Q53 Undescended testicle	0.001	0.998	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.998	0.002
E03.8 Other specified hypothyroidism	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.001	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.001	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.001	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.998	0.001
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.001
D80 Immunodeficiency with predominantly antibody defects	0.000	0.998	0.001
I77.8 Other specified disorders of arteries and arterioles	0.000	0.998	0.002
K11.6 Mucocele of salivary gland	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.001	0.998	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.000	0.998	0.001
H13.2 Conjunctivitis in other diseases classified elsewhere	0.000	0.998	0.001
H13.0 Filarial infection of conjunctiva	0.000	0.998	0.001
D66 Hereditary factor VIII deficiency	0.000	0.998	0.001
D81 Combined immunodeficiencies	0.001	0.998	0.001
L90 Atrophic disorders of skin	0.000	0.998	0.002
D82 Immunodeficiency associated with other major defects	0.001	0.998	0.001
O64.8 Obstructed labour due to other malposition and malpresentation	0.001	0.998	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.001
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.998	0.001
I33 Acute and subacute endocarditis	0.002	0.998	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
L90.5 Scar conditions and fibrosis of skin	0.000	0.998	0.002
B59 Pneumocystosis	0.001	0.998	0.000
D83 Common variable immunodeficiency	0.001	0.998	0.001
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.998	0.001
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.001
H13.3 Ocular pemphigoid	0.000	0.998	0.001
Q55.9 Congenital malformation of male genital organ, unspecified	0.001	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.001	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.001	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.001	0.998	0.000
Q55.3 Atresia of vas deferens	0.001	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.001	0.998	0.000
Q55.0 Absence and aplasia of testis	0.001	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.000	0.998	0.001
I31.9 Disease of pericardium, unspecified	0.000	0.999	0.001
I45.4 Nonspecific intraventricular block	0.001	0.999	0.000
D55 Anaemia due to enzyme disorders	0.000	0.999	0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.999	0.000
F05.0 Delirium not superimposed on dementia, so described	0.000	0.999	0.001
I45.9 Conduction disorder, unspecified	0.001	0.999	0.000
Q53.2 Undescended testicle, bilateral	0.001	0.999	0.000
C53 Malignant neoplasm of cervix uteri	0.001	0.999	0.000
D57 Sickle-cell disorders	0.000	0.999	0.001
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.001	0.999	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.999	0.001
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.999	0.001
Q28.2 Arteriovenous malformation of cerebral vessels	0.001	0.999	0.000
Q53.9 Undescended testicle, unspecified	0.001	0.999	0.000
Q53.0 Ectopic testis	0.001	0.999	0.000
Q55.6 Other congenital malformations of penis	0.001	0.999	0.000
D84 Other immunodeficiencies	0.001	0.999	0.001
M79.18 Myalgia (Other)	0.000	0.999	0.001
D58.2 Other haemoglobinopathies	0.000	0.999	0.001
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.999	0.001
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.999	0.001
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.999	0.001
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.999	0.001
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.999	0.001
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.001	0.999	0.000
H50.9 Strabismus, unspecified	0.001	0.999	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.001	0.999	0.000
D69.0 Allergic purpura	0.000	0.999	0.001
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.001
D81.8 Other combined immunodeficiencies	0.001	0.999	0.001
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.001
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.001
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.001
D81.4 Nezelof's syndrome	0.001	0.999	0.001
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.001
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.001
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.001
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.001
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.001	0.999	0.000
S05.1 Contusion of eyeball and orbital tissues	0.000	0.999	0.001
D58.0 Hereditary spherocytosis	0.000	0.999	0.001
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.001
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.001
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.001
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.001
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.001
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.001
L90.6 Striae atrophicae	0.000	0.999	0.001
L90.4 Acrodermatitis chronica atrophicans	0.000	0.999	0.001
L90.3 Atrophoderma of Pasini and Pierini	0.000	0.999	0.001
L90.2 Anetoderma of Jadassohn-Pellizzari	0.000	0.999	0.001
L90.1 Anetoderma of Schweninger-Buzzi	0.000	0.999	0.001
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.999	0.001
X51.9 Unspecified place	0.001	0.999	0.000
K62.4 Stenosis of anus and rectum	0.000	0.999	0.001
Q55.2 Other congenital malformations of testis and scrotum	0.001	0.999	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.001	0.999	0.000
M79.11 Myalgia (Shoulder region)	0.000	0.999	0.001
A41.1 Septicaemia due to other specified staphylococcus	0.001	0.999	0.000
C18.2 Ascending colon	0.001	0.999	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.999	0.001
D82.1 Di George's syndrome	0.001	0.999	0.001
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.001
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.001
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.001
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.001
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.999	0.001
R23.3 Spontaneous ecchymoses	0.000	0.999	0.001
S22.2 Fracture of sternum	0.001	0.999	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.000	0.999	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
C53.0 Endocervix	0.001	0.999	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.999	0.001
D55.8 Other anaemias due to enzyme disorders	0.000	0.999	0.001
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.999	0.001
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.999	0.001
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.999	0.001
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.999	0.001
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.999	0.001
D58.1 Hereditary elliptocytosis	0.000	0.999	0.001
F05.1 Delirium superimposed on dementia	0.000	0.999	0.001
I45.0 Right fascicular block	0.001	0.999	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.999	0.001
E80.4 Gilbert's syndrome	0.001	0.999	0.000
T42.4 Benzodiazepines	0.000	0.999	0.001
D56 Thalassaemia	0.000	0.999	0.001
I45 Other conduction disorders	0.001	0.999	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.001	0.999	0.000
C53.8 Overlapping lesion of cervix uteri	0.001	0.999	0.000
C53.1 Exocervix	0.001	0.999	0.000
C82.2 Large cell, follicular	0.000	0.999	0.001
D57.8 Other sickle-cell disorders	0.000	0.999	0.001
D57.3 Sickle-cell trait	0.000	0.999	0.001
D57.2 Double heterozygous sickling disorders	0.000	0.999	0.001
D57.0 Sickle-cell anaemia with crisis	0.000	0.999	0.001
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.001
L93.0 Discoid lupus erythematosus	0.000	0.999	0.001
C90.2 Plasmacytoma, extramedullary	0.000	0.999	0.001
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.001
F05.8 Other delirium	0.000	0.999	0.001
L90.9 Atrophic disorder of skin, unspecified	0.000	0.999	0.001
N82.3 Fistula of vagina to large intestine	0.000	0.999	0.001
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.001	0.999	0.000
O64.2 Obstructed labour due to face presentation	0.001	0.999	0.000
S02.4 Fracture of malar and maxillary bones	0.000	0.999	0.001
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.999	0.001
D59 Acquired haemolytic anaemia	0.000	0.999	0.001
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.001	0.999	0.000
D57.1 Sickle-cell anaemia without crisis	0.000	0.999	0.001
D84.8 Other specified immunodeficiencies	0.001	0.999	0.001
D84.1 Defects in the complement system	0.001	0.999	0.001
I71.3 Abdominal aortic aneurysm, ruptured	0.001	0.999	0.000
O64.5 Obstructed labour due to compound presentation	0.001	0.999	0.000
O64.4 Obstructed labour due to shoulder presentation	0.001	0.999	0.000
O64.3 Obstructed labour due to brow presentation	0.001	0.999	0.000
M43.29 Other fusion of spine (Site unspecified)	0.001	0.999	0.000
M43.26 Other fusion of spine (Lumbar region)	0.001	0.999	0.000
S22.21 Fracture of sternum (open)	0.001	0.999	0.000
D02.4 Respiratory system, unspecified	0.000	0.999	0.001
D02.3 Other parts of respiratory system	0.000	0.999	0.001
D02.2 Bronchus and lung	0.000	0.999	0.001
D02.1 Trachea	0.000	0.999	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
D89.3 Immune reconstitution syndrome	0.001	0.999	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.999	0.000
E80.1 Porphyria cutanea tarda	0.001	0.999	0.000
K62.6 Ulcer of anus and rectum	0.001	0.999	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
M25.57 Pain in joint (Ankle and foot)	0.000	0.999	0.001
D56.9 Thalassaemia, unspecified	0.000	0.999	0.001
D56.8 Other thalassaemias	0.000	0.999	0.001
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.999	0.001
D56.2 Delta-beta thalassaemia	0.000	0.999	0.001
D56.0 Alpha thalassaemia	0.000	0.999	0.001
D84.9 Immunodeficiency, unspecified	0.000	0.999	0.001
D89.2 Hypergammaglobulinaemia, unspecified	0.001	0.999	0.000
D89.1 Cryoglobulinaemia	0.001	0.999	0.000
L90.8 Other atrophic disorders of skin	0.000	0.999	0.001
N35.8 Other urethral stricture	0.001	0.999	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.001	0.999	0.000
M21.27 Flexion deformity (Ankle and foot)	0.000	0.999	0.001
M62.82 Other specified disorders of muscle (Upper arm)	0.000	0.999	0.001
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.001	0.999	0.000
Q79.6 Ehlers-Danlos syndrome	0.001	0.999	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.999	0.001
I45.2 Bifascicular block	0.001	0.999	0.000
J04.1 Acute tracheitis	0.000	0.999	0.001
M79.1 Myalgia	0.000	0.999	0.001
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.001	0.999	0.000
Q53.1 Undescended testicle, unilateral	0.001	0.999	0.001
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.999	0.001
D44.3 Pituitary gland	0.001	0.999	0.000
D59.8 Other acquired haemolytic anaemias	0.000	0.999	0.001
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.999	0.001
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.999	0.001
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.999	0.001
D59.3 Haemolytic-uraemic syndrome	0.000	0.999	0.001
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.999	0.001
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.999	0.001
I07.1 Tricuspid insufficiency	0.001	0.999	0.000
L92.0 Granuloma annulare	0.000	0.999	0.001
R90 Abnormal findings on diagnostic imaging of central nervous system	0.001	0.999	0.000
M48.04 Spinal stenosis (Thoracic region)	0.001	0.999	0.000
M53.96 Dorsopathy, unspecified (Lumbar region)	0.001	0.999	0.000
M94.88 Other specified disorders of cartilage (Other)	0.001	0.999	0.000
S32.40 Fracture of acetabulum (closed)	0.001	0.999	0.000
D37.7 Other digestive organs	0.000	0.999	0.001
D56.1 Beta thalassaemia	0.000	0.999	0.001
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.999	0.001
K29.0 Acute haemorrhagic gastritis	0.000	0.999	0.001
C55 Malignant neoplasm of uterus, part unspecified	0.001	0.999	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.999	0.001
M41.99 Scoliosis, unspecified (Site unspecified)	0.001	0.999	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.999	0.001
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations