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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2328519
log Bayes Factor = 16.0477
Chromosome 6   position 144,142,629  (GRCh37) Explore rs2328519 on Ensembl!
Variant rs2328519 is part of Cluster X0244

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
M70-M79 Other soft tissue disorders
0.994 0.006 0.000
Chapter II Neoplasms
0.994 0.006 0.000
T81 Complications of procedures, not elsewhere classified
0.990 0.010 0.000
Chapter XXI Factors influencing health status and contact with health services
0.986 0.014 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.985 0.015 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.981 0.019 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.980 0.020 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.974 0.026 0.000
Chapter XX External causes of morbidity and mortality
0.971 0.029 0.000
M79.6 Pain in limb
0.969 0.031 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.969 0.031 0.000
E10-E14 Diabetes mellitus
0.966 0.034 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.963 0.037 0.000
Chapter V Mental and behavioural disorders
0.961 0.039 0.000
M20-M25 Other joint disorders
0.959 0.041 0.000
M50-M54 Other dorsopathies
0.955 0.045 0.000
N20-N23 Urolithiasis
0.950 0.050 0.000
N10-N16 Renal tubulo-interstitial diseases
0.949 0.051 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.945 0.055 0.000
E11 Non-insulin-dependent diabetes mellitus
0.943 0.057 0.000
E65-E68 Obesity and other hyperalimentation
0.943 0.057 0.000
N00-N08 Glomerular diseases
0.939 0.061 0.000
M79.66 Pain in limb (Lower leg)
0.936 0.064 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.925 0.075 0.000
Chapter VI Diseases of the nervous system
0.923 0.077 0.000
N13 Obstructive and reflux uropathy
0.922 0.078 0.000
M20 Acquired deformities of fingers and toes
0.918 0.082 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.915 0.085 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.914 0.086 0.000
R50-R69 General symptoms and signs
0.910 0.090 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.910 0.090 0.000
E66 Obesity
0.903 0.097 0.000
E00-E07 Disorders of thyroid gland
0.901 0.099 0.000
N20 Calculus of kidney and ureter
0.900 0.100 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.900 0.100 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.899 0.101 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.897 0.103 0.000
N60-N64 Disorders of breast
0.895 0.105 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.894 0.106 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.892 0.108 0.000
E50-E64 Other nutritional deficiencies
0.891 0.109 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.889 0.111 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.881 0.119 0.000
Chapter VII Diseases of the eye and adnexa
0.877 0.123 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.875 0.125 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.874 0.126 0.000
E66.9 Obesity, unspecified
0.873 0.127 0.000
R60 Oedema, not elsewhere classified
0.872 0.128 0.000
Chapter X Diseases of the respiratory system
0.870 0.130 0.000
F41 Other anxiety disorders
0.870 0.130 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.865 0.135 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.865 0.135 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.865 0.135 0.000
M75 Shoulder lesions
0.862 0.138 0.000
S00-S09 Injuries to the head
0.861 0.139 0.000
C51-C58 Malignant neoplasms of female genital organs
0.860 0.140 0.000
N20.0 Calculus of kidney
0.856 0.144 0.000
F41.2 Mixed anxiety and depressive disorder
0.856 0.144 0.000
G20-G26 Extrapyramidal and movement disorders
0.852 0.148 0.000
Z03.8 Observation for other suspected diseases and conditions
0.850 0.150 0.000
N13.3 Other and unspecified hydronephrosis
0.850 0.150 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.845 0.155 0.000
M54 Dorsalgia
0.845 0.155 0.000
M15-M19 Arthrosis
0.844 0.156 0.000
C91 Lymphoid leukaemia
0.838 0.162 0.000
Z04 Examination and observation for other reasons
0.832 0.168 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.832 0.168 0.000
N03 Chronic nephritic syndrome
0.831 0.169 0.000
T51 Toxic effect of alcohol
0.829 0.171 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.828 0.172 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.827 0.173 0.000
M25 Other joint disorders, not elsewhere classified
0.826 0.174 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.820 0.180 0.000
S50-S59 Injuries to the elbow and forearm
0.817 0.183 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.817 0.183 0.000
S80-S89 Injuries to the knee and lower leg
0.816 0.184 0.000
C15-C26 Malignant neoplasms of digestive organs
0.813 0.187 0.000
E11.9 Without complications
0.812 0.188 0.000
M51 Other intervertebral disk disorders
0.811 0.189 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.811 0.189 0.000
W00-W19 Falls
0.811 0.189 0.000
E20-E35 Disorders of other endocrine glands
0.808 0.191 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.808 0.192 0.000
Chapter I Certain infectious and parasitic diseases
0.808 0.192 0.000
M45-M49 Spondylopathies
0.806 0.194 0.000
E11.5 With peripheral circulatory complications
0.804 0.196 0.000
C85.1 B-cell lymphoma, unspecified
0.802 0.198 0.000
R53 Malaise and fatigue
0.801 0.199 0.000
J95-J99 Other diseases of the respiratory system
0.801 0.199 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.801 0.199 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.799 0.201 0.000
Chapter VIII Diseases of the ear and mastoid process
0.797 0.203 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.794 0.206 0.000
E40-E46 Malnutrition
0.794 0.206 0.000
R60.0 Localised oedema
0.793 0.207 0.000
M79.60 Pain in limb (Multiple sites)
0.792 0.208 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.792 0.208 0.000
T66-T78 Other and unspecified effects of external causes
0.792 0.208 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.791 0.209 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.790 0.210 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.789 0.211 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.788 0.212 0.000
M20.4 Other hammer toe(s) (acquired)
0.788 0.212 0.000
R60.9 Oedema, unspecified
0.788 0.212 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.788 0.212 0.000
N64 Other disorders of breast
0.787 0.213 0.000
E11.2 With renal complications
0.787 0.213 0.000
Z92 Personal history of medical treatment
0.787 0.213 0.000
R01 Cardiac murmurs and other cardiac sounds
0.786 0.214 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.785 0.215 0.000
N21 Calculus of lower urinary tract
0.784 0.216 0.000
C50-C50 Malignant neoplasm of breast
0.784 0.216 0.000
M79.0 Rheumatism, unspecified
0.784 0.216 0.000
M20.2 Hallux rigidus
0.783 0.217 0.000
R80 Isolated proteinuria
0.783 0.217 0.000
M76 Enthesopathies of lower limb, excluding foot
0.782 0.218 0.000
M19 Other arthrosis
0.782 0.218 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.781 0.219 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.779 0.221 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.779 0.221 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.778 0.222 0.000
M79.8 Other specified soft tissue disorders
0.778 0.222 0.000
T51.0 Ethanol
0.778 0.222 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.775 0.224 0.000
E03 Other hypothyroidism
0.775 0.225 0.000
E11.3 With ophthalmic complications
0.773 0.227 0.000
M54.5 Low back pain
0.773 0.227 0.000
C34 Malignant neoplasm of bronchus and lung
0.772 0.228 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.772 0.228 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.772 0.228 0.000
M80-M85 Disorders of bone density and structure
0.771 0.228 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.770 0.230 0.000
R59 Enlarged lymph nodes
0.769 0.231 0.000
M79.69 Pain in limb (Site unspecified)
0.769 0.231 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.769 0.231 0.000
E11.4 With neurological complications
0.768 0.232 0.000
M50 Cervical disk disorders
0.768 0.232 0.000
G20 Parkinson's disease
0.767 0.233 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.767 0.233 0.000
E04 Other non-toxic goitre
0.765 0.235 0.000
F30-F39 Mood [affective] disorders
0.762 0.238 0.000
N60 Benign mammary dysplasia
0.761 0.239 0.000
M79.7 Fibromyalgia
0.761 0.239 0.000
R06 Abnormalities of breathing
0.761 0.239 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.760 0.240 0.000
C56 Malignant neoplasm of ovary
0.760 0.240 0.000
J40-J47 Chronic lower respiratory diseases
0.756 0.244 0.000
M20.5 Other deformities of toe(s) (acquired)
0.755 0.245 0.000
N03.9 Unspecified
0.754 0.246 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.754 0.246 0.000
J98 Other respiratory disorders
0.752 0.248 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.752 0.248 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.751 0.249 0.000
H25-H28 Disorders of lens
0.749 0.251 0.000
N63 Unspecified lump in breast
0.748 0.252 0.000
Z03.4 Observation for suspected myocardial infarction
0.746 0.254 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.745 0.255 0.000
F99-F99 Unspecified mental disorder
0.745 0.255 0.000
V10-V19 Pedal cyclist injured in transport accident
0.744 0.256 0.000
M19.9 Arthrosis, unspecified
0.744 0.256 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.744 0.256 0.000
R42 Dizziness and giddiness
0.743 0.257 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.743 0.257 0.000
E53 Deficiency of other B group vitamins
0.743 0.257 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.742 0.257 0.000
M75.1 Rotator cuff syndrome
0.742 0.258 0.000
M53 Other dorsopathies, not elsewhere classified
0.742 0.258 0.000
S90-S99 Injuries to the ankle and foot
0.741 0.259 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.740 0.260 0.000
G90-G99 Other disorders of the nervous system
0.739 0.261 0.000
N13.4 Hydroureter
0.739 0.261 0.000
Chapter XXII Codes for special purposes
0.739 0.261 0.000
S02 Fracture of skull and facial bones
0.737 0.263 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.737 0.263 0.000
C91.1 Chronic lymphocytic leukaemia
0.736 0.264 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.734 0.266 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.732 0.267 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.732 0.268 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.731 0.269 0.000
R05 Cough
0.731 0.269 0.000
N05 Unspecified nephritic syndrome
0.730 0.269 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.730 0.270 0.000
M20.1 Hallux valgus (acquired)
0.730 0.270 0.000
E55 Vitamin D deficiency
0.730 0.270 0.000
F60-F69 Disorders of adult personality and behaviour
0.729 0.270 0.000
H40-H42 Glaucoma
0.729 0.271 0.000
D00-D09 In situ neoplasms
0.726 0.274 0.000
F43 Reaction to severe stress, and adjustment disorders
0.725 0.275 0.000
O60-O75 Complications of labour and delivery
0.725 0.275 0.000
M86-M90 Other osteopathies
0.724 0.276 0.000
N02 Recurrent and persistent haematuria
0.723 0.277 0.000
G70-G73 Diseases of myoneural junction and muscle
0.722 0.278 0.000
Z85 Personal history of malignant neoplasm
0.721 0.279 0.000
N72 Inflammatory disease of cervix uteri
0.721 0.279 0.000
M40-M43 Deforming dorsopathies
0.720 0.280 0.000
Z51 Other medical care
0.720 0.280 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.720 0.280 0.000
W20-W49 Exposure to inanimate mechanical forces
0.717 0.283 0.000
N25-N29 Other disorders of kidney and ureter
0.717 0.283 0.000
J98.1 Pulmonary collapse
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.716 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
T86 Failure and rejection of transplanted organs and tissues
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
S70-S79 Injuries to the hip and thigh
0.716 0.284 0.000
S01 Open wound of head
0.715 0.285 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.714 0.286 0.000
M65-M68 Disorders of synovium and tendon
0.714 0.286 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.713 0.287 0.000
M71 Other bursopathies
0.713 0.287 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.713 0.287 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.713 0.287 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.713 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
N17-N19 Renal failure
0.713 0.287 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.712 0.288 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.712 0.288 0.000
M75.0 Adhesive capsulitis of shoulder
0.712 0.288 0.000
R02 Gangrene, not elsewhere classified
0.711 0.289 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.711 0.289 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.710 0.290 0.000
T81.9 Unspecified complication of procedure
0.710 0.290 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.710 0.290 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.710 0.290 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.710 0.290 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.710 0.290 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.710 0.290 0.000
E10 Insulin-dependent diabetes mellitus
0.710 0.290 0.000
G25 Other extrapyramidal and movement disorders
0.709 0.291 0.000
H55-H59 Other disorders of eye and adnexa
0.709 0.291 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.709 0.291 0.000
R01.1 Cardiac murmur, unspecified
0.709 0.291 0.000
C18 Malignant neoplasm of colon
0.708 0.292 0.000
M51.2 Other specified intervertebral disk displacement
0.707 0.293 0.000
R47-R49 Symptoms and signs involving speech and voice
0.707 0.293 0.000
M21 Other acquired deformities of limbs
0.706 0.294 0.000
M77 Other enthesopathies
0.706 0.294 0.000
M79.9 Soft tissue disorder, unspecified
0.706 0.294 0.000
M79.5 Residual foreign body in soft tissue
0.706 0.294 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.706 0.294 0.000
M79.3 Panniculitis, unspecified
0.706 0.294 0.000
M79.2 Neuralgia and neuritis, unspecified
0.706 0.294 0.000
M79.1 Myalgia
0.706 0.294 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.706 0.294 0.000
T42.4 Benzodiazepines
0.706 0.294 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.705 0.295 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.704 0.296 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.704 0.296 0.000
C95 Leukaemia of unspecified cell type
0.704 0.296 0.000
C94 Other leukaemias of specified cell type
0.704 0.296 0.000
C93 Monocytic leukaemia
0.704 0.296 0.000
C92 Myeloid leukaemia
0.704 0.296 0.000
C88 Malignant immunoproliferative diseases
0.704 0.296 0.000
C86 Other specified types of T/NK-cell lymphoma
0.704 0.296 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.704 0.296 0.000
C81 Hodgkin's disease
0.704 0.296 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.703 0.297 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.702 0.298 0.000
M23 Internal derangement of knee
0.701 0.299 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.700 0.300 0.000
M25.5 Pain in joint
0.699 0.301 0.000
N64.5 Other signs and symptoms in breast
0.699 0.301 0.000
Z04.9 Examination and observation for unspecified reason
0.699 0.301 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.699 0.301 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.698 0.301 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.698 0.301 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.698 0.301 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.698 0.301 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.698 0.301 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.698 0.301 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.698 0.301 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.698 0.301 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.698 0.301 0.000
T36 Poisoning by systemic antibiotics
0.698 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.696 0.303 0.000
Y35-Y36 Legal intervention and operations of war
0.696 0.303 0.000
Y10-Y34 Event of undetermined intent
0.696 0.303 0.000
Y00-Y09 Assault
0.696 0.303 0.000
X85-X99 Assault
0.696 0.303 0.000
X60-X84 Intentional self-harm
0.696 0.303 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.696 0.303 0.000
X50-X57 Overexertion, travel and privation
0.696 0.303 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.696 0.303 0.000
X30-X39 Exposure to forces of nature
0.696 0.303 0.000
X20-X29 Contact with venomous animals and plants
0.696 0.303 0.000
X10-X19 Contact with heat and hot substances
0.696 0.303 0.000
X00-X09 Exposure to smoke, fire and flames
0.696 0.303 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.696 0.303 0.000
W75-W84 Other accidental threats to breathing
0.696 0.303 0.000
W65-W74 Accidental drowning and submersion
0.696 0.303 0.000
W50-W64 Exposure to animate mechanical forces
0.696 0.303 0.000
V98-V99 Other and unspecified transport accidents
0.696 0.303 0.000
V95-V97 Air and space transport accidents
0.696 0.303 0.000
V90-V94 Water transport accidents
0.696 0.303 0.000
V80-V89 Other land transport accidents
0.696 0.303 0.000
V70-V79 Bus occupant injured in transport accident
0.696 0.303 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.696 0.303 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.696 0.303 0.000
V40-V49 Car occupant injured in transport accident
0.696 0.303 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.696 0.303 0.000
V20-V29 Motorcycle rider injured in transport accident
0.696 0.303 0.000
V01-V09 Pedestrian injured in transport accident
0.696 0.303 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.695 0.305 0.000
R59.0 Localised enlarged lymph nodes
0.695 0.305 0.000
M79.68 Pain in limb (Other)
0.695 0.305 0.000
M79.64 Pain in limb (Hand)
0.695 0.305 0.000
M79.63 Pain in limb (Forearm)
0.695 0.305 0.000
M79.61 Pain in limb (Shoulder region)
0.695 0.305 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.695 0.305 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.694 0.306 0.000
E13 Other specified diabetes mellitus
0.693 0.307 0.000
E12 Malnutrition-related diabetes mellitus
0.693 0.307 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.692 0.307 0.000
C53 Malignant neoplasm of cervix uteri
0.692 0.308 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.692 0.308 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.690 0.309 0.000
Z10 Routine general health check-up of defined subpopulation
0.690 0.309 0.000
M31 Other necrotising vasculopathies
0.690 0.309 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.690 0.310 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.689 0.311 0.000
F80-F89 Disorders of psychological development
0.689 0.311 0.000
F70-F79 Mental retardation
0.689 0.311 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.689 0.311 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.689 0.311 0.000
Z51.2 Other chemotherapy
0.688 0.312 0.000
C83.3 Large cell (diffuse)
0.688 0.312 0.000
S40-S49 Injuries to the shoulder and upper arm
0.688 0.312 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.688 0.312 0.000
M34 Systemic sclerosis
0.688 0.312 0.000
M33 Dermatopolymyositis
0.688 0.312 0.000
M32 Systemic lupus erythematosus
0.688 0.312 0.000
M30 Polyarteritis nodosa and related conditions
0.688 0.312 0.000
E61 Deficiency of other nutrient elements
0.687 0.313 0.000
N20.1 Calculus of ureter
0.687 0.313 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.686 0.314 0.000
E03.9 Hypothyroidism, unspecified
0.685 0.315 0.000
R61 Hyperhidrosis
0.683 0.317 0.000
R00 Abnormalities of heart beat
0.682 0.318 0.000
D46 Myelodysplastic syndromes
0.681 0.319 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.681 0.319 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.681 0.319 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.680 0.319 0.000
M05-M14 Inflammatory polyarthropathies
0.680 0.320 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.680 0.320 0.000
N15 Other renal tubulo-interstitial diseases
0.680 0.320 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.680 0.320 0.000
N11 Chronic tubulo-interstitial nephritis
0.680 0.320 0.000
N10 Acute tubulo-interstitial nephritis
0.680 0.320 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.679 0.321 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.678 0.322 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.678 0.322 0.000
C85.0 Lymphosarcoma
0.678 0.322 0.000
M20.0 Deformity of finger(s)
0.677 0.323 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.677 0.323 0.000
B35-B49 Mycoses
0.677 0.323 0.000
Z90.1 Acquired absence of breast(s)
0.677 0.323 0.000
E11.8 With unspecified complications
0.676 0.324 0.000
E11.7 With multiple complications
0.676 0.324 0.000
E11.6 With other specified complications
0.676 0.324 0.000
E11.1 With ketoacidosis
0.676 0.324 0.000
E11.0 With coma
0.676 0.324 0.000
E67 Other hyperalimentation
0.676 0.324 0.000
E68 Sequelae of hyperalimentation
0.676 0.324 0.000
E65 Localised adiposity
0.676 0.324 0.000
R55 Syncope and collapse
0.676 0.324 0.000
E14 Unspecified diabetes mellitus
0.675 0.324 0.000
R68 Other general symptoms and signs
0.675 0.325 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.674 0.326 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.674 0.326 0.000
N06 Isolated proteinuria with specified morphological lesion
0.674 0.326 0.000
N04 Nephrotic syndrome
0.674 0.326 0.000
N01 Rapidly progressive nephritic syndrome
0.674 0.326 0.000
N00 Acute nephritic syndrome
0.674 0.326 0.000
Z04.8 Examination and observation for other specified reasons
0.673 0.327 0.000
S82 Fracture of lower leg, including ankle
0.671 0.329 0.000
S06 Intracranial injury
0.668 0.332 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.667 0.333 0.000
R52 Pain, not elsewhere classified
0.666 0.334 0.000
S60-S69 Injuries to the wrist and hand
0.666 0.334 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.666 0.334 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.666 0.334 0.000
M72 Fibroblastic disorders
0.665 0.335 0.000
N21.0 Calculus in bladder
0.665 0.335 0.000
D45 Polycythaemia vera
0.665 0.335 0.000
F31 Bipolar affective disorder
0.665 0.335 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.664 0.336 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.664 0.336 0.000
Y95 Nosocomial condition
0.664 0.336 0.000
C34.3 Lower lobe, bronchus or lung
0.664 0.336 0.000
H53-H54 Visual disturbances and blindness
0.664 0.336 0.000
A30-A49 Other bacterial diseases
0.663 0.337 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.663 0.337 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.663 0.337 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.663 0.337 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.663 0.337 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.663 0.337 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.662 0.338 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.662 0.338 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.662 0.338 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.661 0.339 0.000
N13.8 Other obstructive and reflux uropathy
0.661 0.339 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.661 0.339 0.000
N13.6 Pyonephrosis
0.661 0.339 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.661 0.339 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.661 0.339 0.000
N23 Unspecified renal colic
0.661 0.339 0.000
C64-C68 Malignant neoplasms of urinary tract
0.660 0.340 0.000
S52 Fracture of forearm
0.659 0.341 0.000
M20.3 Other deformity of hallux (acquired)
0.658 0.341 0.000
E66.8 Other obesity
0.657 0.343 0.000
N20.2 Calculus of kidney with calculus of ureter
0.657 0.343 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.656 0.344 0.000
Y86 Sequelae of other accidents
0.656 0.344 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.656 0.344 0.000
Z03.3 Observation for suspected nervous system disorder
0.656 0.344 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.656 0.344 0.000
Z03.0 Observation for suspected tuberculosis
0.656 0.344 0.000
F48 Other neurotic disorders
0.655 0.344 0.000
F45 Somatoform disorders
0.655 0.344 0.000
F44 Dissociative [conversion] disorders
0.655 0.344 0.000
F42 Obsessive-compulsive disorder
0.655 0.344 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.655 0.345 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.655 0.345 0.000
S20-S29 Injuries to the thorax
0.654 0.346 0.000
N99-N99 Other disorders of the genitourinary system
0.654 0.346 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.654 0.346 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.653 0.347 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.653 0.347 0.000
R62 Lack of expected normal physiological development
0.653 0.347 0.000
R57 Shock, not elsewhere classified
0.653 0.347 0.000
R64 Cachexia
0.653 0.347 0.000
R58 Haemorrhage, not elsewhere classified
0.653 0.347 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.653 0.347 0.000
W19 Unspecified fall
0.652 0.348 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.652 0.348 0.000
M19.94 Arthrosis, unspecified (Hand)
0.651 0.349 0.000
R45 Symptoms and signs involving emotional state
0.651 0.349 0.000
H25 Senile cataract
0.651 0.349 0.000
C34.9 Bronchus or lung, unspecified
0.650 0.349 0.000
M54.56 Low back pain (Lumbar region)
0.650 0.350 0.000
F40 Phobic anxiety disorders
0.649 0.351 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.648 0.351 0.000
G30-G32 Other degenerative diseases of the nervous system
0.647 0.353 0.000
M22 Disorders of patella
0.647 0.353 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.647 0.353 0.000
E66.1 Drug-induced obesity
0.647 0.353 0.000
E66.0 Obesity due to excess calories
0.647 0.353 0.000
E46 Unspecified protein-energy malnutrition
0.647 0.353 0.000
H43-H45 Disorders of vitreous body and globe
0.647 0.353 0.000
E07 Other disorders of thyroid
0.646 0.354 0.000
E06 Thyroiditis
0.646 0.354 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.646 0.354 0.000
E00 Congenital iodine-deficiency syndrome
0.646 0.354 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.646 0.354 0.000
N20.9 Urinary calculus, unspecified
0.646 0.354 0.000
T65 Toxic effect of other and unspecified substances
0.645 0.354 0.000
T63 Toxic effect of contact with venomous animals
0.645 0.354 0.000
T62 Toxic effect of other noxious substances eaten as food
0.645 0.354 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.645 0.354 0.000
T60 Toxic effect of pesticides
0.645 0.354 0.000
T59 Toxic effect of other gases, fumes and vapours
0.645 0.354 0.000
T57 Toxic effect of other inorganic substances
0.645 0.354 0.000
T56 Toxic effect of metals
0.645 0.354 0.000
T54 Toxic effect of corrosive substances
0.645 0.354 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.645 0.354 0.000
T52 Toxic effect of organic solvents
0.645 0.354 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.645 0.354 0.000
T58 Toxic effect of carbon monoxide
0.645 0.354 0.000
T55 Toxic effect of soaps and detergents
0.645 0.354 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.645 0.355 0.000
T43.2 Other and unspecified antidepressants
0.645 0.355 0.000
R63 Symptoms and signs concerning food and fluid intake
0.645 0.355 0.000
O85-O92 Complications predominantly related to the puerperium
0.645 0.355 0.000
R40 Somnolence, stupor and coma
0.644 0.355 0.000
M24 Other specific joint derangements
0.644 0.356 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.644 0.356 0.000
M18 Arthrosis of first carpometacarpal joint
0.644 0.356 0.000
T78 Adverse effects, not elsewhere classified
0.643 0.357 0.000
Z90.2 Acquired absence of lung [part of]
0.643 0.357 0.000
M54.4 Lumbago with sciatica
0.643 0.357 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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