TreeWAS – Variant ID: rs2328874

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
E83 Disorders of mineral metabolism	0.000	0.920	0.080
J92.0 Pleural plaque with presence of asbestos	0.059	0.941	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.942	0.057
E83.8 Other disorders of mineral metabolism	0.000	0.942	0.057
E83.2 Disorders of zinc metabolism	0.000	0.942	0.057
E83.0 Disorders of copper metabolism	0.000	0.942	0.057
T39.1 4-Aminophenol derivatives	0.000	0.943	0.057
E83.4 Disorders of magnesium metabolism	0.000	0.946	0.054
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.958	0.042
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.962	0.038
J92 Pleural plaque	0.037	0.963	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.964	0.036
K11.5 Sialolithiasis	0.033	0.967	0.000
J92.9 Pleural plaque without asbestos	0.033	0.967	0.000
I51.7 Cardiomegaly	0.030	0.970	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.972	0.028
T39.2 Pyrazolone derivatives	0.000	0.972	0.028
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.973	0.027
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.973	0.027
E83.3 Disorders of phosphorus metabolism	0.000	0.974	0.026
T39.0 Salicylates	0.000	0.975	0.025
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.024	0.976	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.022	0.978	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.021	0.979	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.019	0.981	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.016	0.984	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.016	0.984	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.986	0.014
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.986	0.014
E10.1 With ketoacidosis	0.000	0.986	0.014
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.987	0.013
C19 Malignant neoplasm of rectosigmoid junction	0.013	0.987	0.000
M79.66 Pain in limb (Lower leg)	0.000	0.987	0.013
M79.6 Pain in limb	0.000	0.987	0.013
M79.60 Pain in limb (Multiple sites)	0.000	0.988	0.012
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.988	0.012
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.989	0.011
M79.61 Pain in limb (Shoulder region)	0.000	0.989	0.011
E83.5 Disorders of calcium metabolism	0.000	0.990	0.010
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.991	0.009
D32.0 Cerebral meninges	0.000	0.992	0.008
M79.68 Pain in limb (Other)	0.000	0.992	0.008
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.992	0.008
M79.64 Pain in limb (Hand)	0.000	0.992	0.008
C71.9 Brain, unspecified	0.000	0.993	0.007
D13.1 Stomach	0.000	0.993	0.007
H74 Other disorders of middle ear and mastoid	0.000	0.994	0.006
R90.0 Intracranial space-occupying lesion	0.000	0.994	0.006
M79.63 Pain in limb (Forearm)	0.000	0.994	0.006
E10.2 With renal complications	0.000	0.994	0.006
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.994	0.006
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.994	0.006
E10 Insulin-dependent diabetes mellitus	0.000	0.994	0.006
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.994	0.006
O20.9 Haemorrhage in early pregnancy, unspecified	0.006	0.994	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.994	0.006
H74.4 Polyp of middle ear	0.000	0.995	0.005
H74.1 Adhesive middle ear disease	0.000	0.995	0.005
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.000	0.995	0.005
C71 Malignant neoplasm of brain	0.000	0.995	0.005
D13.5 Extrahepatic bile ducts	0.000	0.995	0.005
E10.6 With other specified complications	0.000	0.995	0.005
D13.4 Liver	0.000	0.995	0.005
D13.3 Other and unspecified parts of small intestine	0.000	0.995	0.005
E10.0 With coma	0.000	0.995	0.005
C71.2 Temporal lobe	0.000	0.995	0.005
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.995	0.005
B00.9 Herpesviral infection, unspecified	0.005	0.995	0.000
H65 Nonsuppurative otitis media	0.000	0.995	0.005
E10.8 With unspecified complications	0.000	0.995	0.005
H65.2 Chronic serous otitis media	0.000	0.995	0.005
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.995	0.005
D13.6 Pancreas	0.000	0.995	0.004
D32 Benign neoplasm of meninges	0.000	0.995	0.005
C71.8 Overlapping lesion of brain	0.000	0.995	0.004
D13.2 Duodenum	0.000	0.996	0.004
H74.0 Tympanosclerosis	0.000	0.996	0.004
C71.3 Parietal lobe	0.000	0.996	0.004
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.996	0.004
C71.0 Cerebrum, except lobes and ventricles	0.000	0.996	0.004
E10.4 With neurological complications	0.000	0.996	0.004
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.000	0.996	0.004
S92.00 Fracture of calcaneus (closed)	0.000	0.996	0.004
E10.7 With multiple complications	0.000	0.996	0.004
E10.5 With peripheral circulatory complications	0.000	0.996	0.004
H65.4 Other chronic nonsuppurative otitis media	0.000	0.996	0.004
C71.6 Cerebellum	0.000	0.996	0.004
N90.4 Leukoplakia of vulva	0.004	0.996	0.000
D13.9 Ill-defined sites within the digestive system	0.000	0.996	0.004
C71.5 Cerebral ventricle	0.000	0.996	0.004
H65.0 Acute serous otitis media	0.000	0.996	0.004
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.000	0.996	0.004
D32.1 Spinal meninges	0.000	0.996	0.004
M79.69 Pain in limb (Site unspecified)	0.000	0.996	0.004
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.996	0.004
M79.2 Neuralgia and neuritis, unspecified	0.000	0.996	0.004
C71.1 Frontal lobe	0.000	0.996	0.004
D32.9 Meninges, unspecified	0.000	0.996	0.004
S02.50 Fracture of tooth (closed)	0.004	0.996	0.000
C50.8 Overlapping lesion of breast	0.000	0.996	0.004
M79 Other soft tissue disorders, not elsewhere classified	0.000	0.996	0.004
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.996	0.003
D13.7 Endocrine pancreas	0.000	0.996	0.003
H65.1 Other acute nonsuppurative otitis media	0.000	0.996	0.003
B00.5 Herpesviral ocular disease	0.003	0.996	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.000	0.996	0.003
H65-H75 Diseases of middle ear and mastoid	0.000	0.997	0.003
B00 Herpesviral [herpes simplex] infections	0.003	0.997	0.000
E70-E90 Metabolic disorders	0.000	0.997	0.003
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
C71.4 Occipital lobe	0.000	0.997	0.003
C71.7 Brain stem	0.000	0.997	0.003
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.000	0.997	0.003
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.000	0.997	0.003
E86 Volume depletion	0.000	0.997	0.003
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.000	0.997	0.003
S22.40 Multiple fractures of ribs (closed)	0.003	0.997	0.000
M79.5 Residual foreign body in soft tissue	0.000	0.997	0.003
H71 Cholesteatoma of middle ear	0.000	0.997	0.003
B00.4 Herpesviral encephalitis	0.003	0.997	0.000
E85 Amyloidosis	0.000	0.997	0.003
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.000	0.997	0.003
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.000	0.997	0.003
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.000	0.997	0.003
G71.0 Muscular dystrophy	0.003	0.997	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.000	0.997	0.003
M79.54 Residual foreign body in soft tissue (Hand)	0.000	0.997	0.003
E10.3 With ophthalmic complications	0.000	0.997	0.003
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.003	0.997	0.000
G93.3 Postviral fatigue syndrome	0.000	0.997	0.003
M79.3 Panniculitis, unspecified	0.000	0.997	0.003
D13.0 Oesophagus	0.000	0.997	0.003
L71.9 Rosacea, unspecified	0.000	0.997	0.003
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.000	0.997	0.003
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.000	0.997	0.003
B00.7 Disseminated herpesviral disease	0.003	0.997	0.000
B00.3 Herpesviral meningitis	0.003	0.997	0.000
B00.0 Eczema herpeticum	0.003	0.997	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.997	0.003
H67 Otitis media in diseases classified elsewhere	0.000	0.997	0.003
M35.0 Sicca syndrome [Sjogren]	0.003	0.997	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.997	0.003
T78.2 Anaphylactic shock, unspecified	0.003	0.997	0.000
E77 Disorders of glycoprotein metabolism	0.000	0.997	0.003
E76 Disorders of glycosaminoglycan metabolism	0.000	0.997	0.003
E72 Other disorders of amino-acid metabolism	0.000	0.997	0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.997	0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.997	0.003
B00.8 Other forms of herpesviral infection	0.003	0.997	0.000
E79 Disorders of purine and pyrimidine metabolism	0.000	0.997	0.003
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.997	0.003
M79.80 Other specified soft tissue disorders (Multiple sites)	0.000	0.997	0.003
I63.8 Other cerebral infarction	0.003	0.997	0.000
M79.7 Fibromyalgia	0.000	0.997	0.003
N30.2 Other chronic cystitis	0.003	0.997	0.000
E85.4 Organ-limited amyloidosis	0.000	0.997	0.003
M79.4 Hypertrophy of (infrapatellar) fat pad	0.000	0.997	0.003
E70 Disorders of aromatic amino-acid metabolism	0.000	0.997	0.003
E85.9 Amyloidosis, unspecified	0.000	0.997	0.003
E84 Cystic fibrosis	0.000	0.997	0.003
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.997	0.003
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.997	0.003
H68 Eustachian salpingitis and obstruction	0.000	0.997	0.002
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.000	0.997	0.002
M79.56 Residual foreign body in soft tissue (Lower leg)	0.000	0.997	0.002
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.000	0.997	0.002
M79.52 Residual foreign body in soft tissue (Upper arm)	0.000	0.997	0.002
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.000	0.997	0.002
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.000	0.997	0.002
G93.6 Cerebral oedema	0.000	0.997	0.003
E85.3 Secondary systemic amyloidosis	0.000	0.997	0.002
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.997	0.002
H66 Suppurative and unspecified otitis media	0.000	0.997	0.003
E85.8 Other amyloidosis	0.000	0.997	0.002
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.997	0.002
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.997	0.002
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.997	0.002
H60.9 Otitis externa, unspecified	0.000	0.997	0.003
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.997	0.003
E74 Other disorders of carbohydrate metabolism	0.000	0.997	0.002
E89.4 Postprocedural ovarian failure	0.000	0.998	0.002
M79.1 Myalgia	0.000	0.998	0.002
E89.3 Postprocedural hypopituitarism	0.000	0.998	0.002
H60.5 Acute otitis externa, non-infective	0.000	0.998	0.002
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.998	0.002
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.998	0.002
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
E73 Lactose intolerance	0.000	0.998	0.002
G95.8 Other specified diseases of spinal cord	0.000	0.998	0.002
M79.67 Pain in limb (Ankle and foot)	0.000	0.998	0.002
H70 Mastoiditis and related conditions	0.000	0.998	0.002
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.998	0.002
C72.0 Spinal cord	0.000	0.998	0.002
M79.39 Panniculitis, unspecified (Site unspecified)	0.000	0.998	0.002
M79.38 Panniculitis, unspecified (Other)	0.000	0.998	0.002
M79.37 Panniculitis, unspecified (Ankle and foot)	0.000	0.998	0.002
M79.36 Panniculitis, unspecified (Lower leg)	0.000	0.998	0.002
M79.35 Panniculitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M79.34 Panniculitis, unspecified (Hand)	0.000	0.998	0.002
M79.33 Panniculitis, unspecified (Forearm)	0.000	0.998	0.002
M79.32 Panniculitis, unspecified (Upper arm)	0.000	0.998	0.002
M79.31 Panniculitis, unspecified (Shoulder region)	0.000	0.998	0.002
M79.30 Panniculitis, unspecified (Multiple sites)	0.000	0.998	0.002
M79.70 Fibromyalgia (Multiple sites)	0.000	0.998	0.002
E80.2 Other porphyria	0.000	0.998	0.002
L27.1 Localised skin eruption due to drugs and medicaments	0.002	0.998	0.000
M79.58 Residual foreign body in soft tissue (Other)	0.000	0.998	0.002
M79.9 Soft tissue disorder, unspecified	0.000	0.998	0.002
H66.4 Suppurative otitis media, unspecified	0.000	0.998	0.002
M79.16 Myalgia (Lower leg)	0.000	0.998	0.002
E88 Other metabolic disorders	0.000	0.998	0.002
R72 Abnormality of white blood cells, not elsewhere classified	0.002	0.998	0.000
M79.53 Residual foreign body in soft tissue (Forearm)	0.000	0.998	0.002
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.998	0.002
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.998	0.002
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.998	0.002
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.998	0.002
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
E71.3 Disorders of fatty-acid metabolism	0.000	0.998	0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.998	0.002
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.998	0.002
E71.0 Maple-syrup-urine disease	0.000	0.998	0.002
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.998	0.002
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.998	0.002
E72.5 Disorders of glycine metabolism	0.000	0.998	0.002
E72.4 Disorders of ornithine metabolism	0.000	0.998	0.002
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.998	0.002
E72.2 Disorders of urea cycle metabolism	0.000	0.998	0.002
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.998	0.002
E72.0 Disorders of amino-acid transport	0.000	0.998	0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.998	0.002
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.998	0.002
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.998	0.002
E76.2 Other mucopolysaccharidoses	0.000	0.998	0.002
E76.1 Mucopolysaccharidosis, type II	0.000	0.998	0.002
E76.0 Mucopolysaccharidosis, type I	0.000	0.998	0.002
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.998	0.002
E77.8 Other disorders of glycoprotein metabolism	0.000	0.998	0.002
E77.1 Defects in glycoprotein degradation	0.000	0.998	0.002
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.998	0.002
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M79.28 Neuralgia and neuritis, unspecified (Other)	0.000	0.998	0.002
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.998	0.002
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.998	0.002
E79.1 Lesch-Nyhan syndrome	0.000	0.998	0.002
S92.0 Fracture of calcaneus	0.000	0.998	0.002
M79.78 Fibromyalgia (Other)	0.000	0.998	0.002
M79.77 Fibromyalgia (Ankle and foot)	0.000	0.998	0.002
M79.76 Fibromyalgia (Lower leg)	0.000	0.998	0.002
M79.75 Fibromyalgia (Pelvic region and thigh)	0.000	0.998	0.002
M79.74 Fibromyalgia (Hand)	0.000	0.998	0.002
M79.73 Fibromyalgia (Forearm)	0.000	0.998	0.002
M79.72 Fibromyalgia (Upper arm)	0.000	0.998	0.002
M79.71 Fibromyalgia (Shoulder region)	0.000	0.998	0.002
E80.6 Other disorders of bilirubin metabolism	0.000	0.998	0.002
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M79.49 Hypertrophy of (infrapatellar) fat pad-Site unspec	0.000	0.998	0.002
M79.48 Hypertrophy of (infrapatellar) fat pad (Other)	0.000	0.998	0.002
M79.47 Hypertrophy of (infrapatellar) fat pad (Ankle and foot)	0.000	0.998	0.002
M79.45 Hypertrophy of (infrapatellar) fat pad (Pelvic region and thigh)	0.000	0.998	0.002
M79.44 Hypertrophy of (infrapatellar) fat pad (Hand)	0.000	0.998	0.002
M79.43 Hypertrophy of (infrapatellar) fat pad (Forearm)	0.000	0.998	0.002
M79.42 Hypertrophy of (infrapatellar) fat pad (Upper arm)	0.000	0.998	0.002
M79.41 Hypertrophy of (infrapatellar) fat pad (Shoulder region)	0.000	0.998	0.002
M79.40 Hypertrophy of (infrapatellar) fat pad (Multiple sites)	0.000	0.998	0.002
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.998	0.002
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.998	0.002
E70.2 Disorders of tyrosine metabolism	0.000	0.998	0.002
E70.1 Other hyperphenylalaninaemias	0.000	0.998	0.002
E70.0 Classical phenylketonuria	0.000	0.998	0.002
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.998	0.002
E84.8 Cystic fibrosis with other manifestations	0.000	0.998	0.002
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.998	0.002
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.998	0.002
C70 Malignant neoplasm of meninges	0.000	0.998	0.002
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.998	0.002
H68.0 Eustachian salpingitis	0.000	0.998	0.002
H60 Otitis externa	0.000	0.998	0.002
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.998	0.002
H73 Other disorders of tympanic membrane	0.000	0.998	0.002
F06.7 Mild cognitive disorder	0.000	0.998	0.002
H66.3 Other chronic suppurative otitis media	0.000	0.998	0.002
M79.8 Other specified soft tissue disorders	0.000	0.998	0.002
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.998	0.002
M79.97 Soft tissue disorder, unspecified (Ankle and foot)	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
E70.3 Albinism	0.000	0.998	0.002
E75.6 Lipid storage disorder, unspecified	0.000	0.998	0.002
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.998	0.002
E75.3 Sphingolipidosis, unspecified	0.000	0.998	0.002
E75.2 Other sphingolipidosis	0.000	0.998	0.002
E75.1 Other gangliosidosis	0.000	0.998	0.002
E75.0 GM2 gangliosidosis	0.000	0.998	0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.998	0.002
H70.1 Chronic mastoiditis	0.000	0.998	0.002
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.998	0.002
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.998	0.002
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.998	0.002
E74.2 Disorders of galactose metabolism	0.000	0.998	0.002
E74.1 Disorders of fructose metabolism	0.000	0.998	0.002
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.998	0.002
E89.5 Postprocedural testicular hypofunction	0.000	0.998	0.002
E89.1 Postprocedural hypoinsulinaemia	0.000	0.998	0.002
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
H66.0 Acute suppurative otitis media	0.000	0.998	0.002
M79.17 Myalgia (Ankle and foot)	0.000	0.998	0.002
M79.14 Myalgia (Hand)	0.000	0.998	0.002
M79.13 Myalgia (Forearm)	0.000	0.998	0.002
M79.12 Myalgia (Upper arm)	0.000	0.998	0.002
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.002	0.998	0.000
E84.9 Cystic fibrosis, unspecified	0.000	0.998	0.002
C72.9 Central nervous system, unspecified	0.000	0.998	0.002
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.998	0.002
C72.5 Other and unspecified cranial nerves	0.000	0.998	0.002
C72.4 Acoustic nerve	0.000	0.998	0.002
C72.3 Optic nerve	0.000	0.998	0.002
C72.2 Olfactory nerve	0.000	0.998	0.002
C72.1 Cauda equina	0.000	0.998	0.002
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.998	0.002
E80.5 Crigler-Najjar syndrome	0.000	0.998	0.002
E80.3 Defects of catalase and peroxydase	0.000	0.998	0.002
E80.1 Porphyria cutanea tarda	0.000	0.998	0.002
E80.0 Hereditary erythropoietic porphyria	0.000	0.998	0.002
H60.8 Other otitis externa	0.000	0.998	0.002
H60.4 Cholesteatoma of external ear	0.000	0.998	0.002
M79.19 Myalgia (Site unspecified)	0.000	0.998	0.002
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.000	0.998	0.002
E73.8 Other lactose intolerance	0.000	0.998	0.002
E73.1 Secondary lactase deficiency	0.000	0.998	0.002
E73.0 Congenital lactase deficiency	0.000	0.998	0.002
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.998	0.002
H68.1 Obstruction of Eustachian tube	0.000	0.998	0.002
H70.8 Other mastoiditis and related conditions	0.000	0.998	0.002
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.998	0.002
M79.94 Soft tissue disorder, unspecified (Hand)	0.000	0.998	0.002
H70.2 Petrositis	0.000	0.998	0.002
M92.7 Juvenile osteochondrosis of metatarsus	0.000	0.998	0.002
C69 Malignant neoplasm of eye and adnexa	0.000	0.998	0.002
M79.18 Myalgia (Other)	0.000	0.998	0.002
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.998	0.002
B00.1 Herpesviral vesicular dermatitis	0.002	0.998	0.000
C53.0 Endocervix	0.000	0.998	0.002
G93.4 Encephalopathy, unspecified	0.000	0.998	0.002
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M79.93 Soft tissue disorder, unspecified (Forearm)	0.000	0.998	0.002
M79.92 Soft tissue disorder, unspecified (Upper arm)	0.000	0.998	0.002
M79.91 Soft tissue disorder, unspecified (Shoulder region)	0.000	0.998	0.002
M79.90 Soft tissue disorder, unspecified (Multiple sites)	0.000	0.998	0.002
H60.2 Malignant otitis externa	0.000	0.998	0.002
H65.3 Chronic mucoid otitis media	0.000	0.998	0.002
C44.7 Skin of lower limb, including hip	0.000	0.998	0.002
E88.3 Tumour lysis syndrome	0.000	0.998	0.002
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.998	0.002
E75.5 Other lipid storage disorders	0.000	0.998	0.002
S22.4 Multiple fractures of ribs	0.002	0.998	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.998	0.000
H70.0 Acute mastoiditis	0.000	0.998	0.002
H69 Other disorders of Eustachian tube	0.001	0.998	0.001
M79.11 Myalgia (Shoulder region)	0.000	0.998	0.002
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.998	0.002
M79.62 Pain in limb (Upper arm)	0.000	0.998	0.001
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.998	0.002
C70.9 Meninges, unspecified	0.000	0.998	0.002
C70.1 Spinal meninges	0.000	0.998	0.002
E74.0 Glycogen storage disease	0.000	0.998	0.002
M79.79 Fibromyalgia (Site unspecified)	0.000	0.998	0.002
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.998	0.002
C70.0 Cerebral meninges	0.000	0.998	0.002
E88.2 Lipomatosis, not elsewhere classified	0.000	0.998	0.002
E89.2 Postprocedural hypoparathyroidism	0.000	0.998	0.002
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.998	0.002
M79.81 Other specified soft tissue disorders (Shoulder region)	0.000	0.998	0.002
C69.3 Choroid	0.000	0.998	0.002
E88.8 Other specified metabolic disorders	0.000	0.998	0.002
H73.1 Chronic myringitis	0.000	0.998	0.002
H73.0 Acute myringitis	0.000	0.998	0.002
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.000	0.998	0.001
G90.2 Horner's syndrome	0.002	0.998	0.000
S12.9 Fracture of neck, part unspecified	0.000	0.998	0.002
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.998	0.002
Z53.9 Procedure not carried out, unspecified reason	0.000	0.998	0.002
E10.9 Without complications	0.000	0.998	0.002
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
H60.0 Abscess of external ear	0.000	0.998	0.002
M79.98 Soft tissue disorder, unspecified (Other)	0.000	0.998	0.001
H72 Perforation of tympanic membrane	0.000	0.998	0.002
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.001	0.998	0.001
C69.2 Retina	0.000	0.998	0.002
H60.3 Other infective otitis externa	0.000	0.998	0.002
S02.5 Fracture of tooth	0.002	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
C69.8 Overlapping lesion of eye and adnexa	0.000	0.998	0.001
C69.5 Lachrymal gland and duct	0.000	0.998	0.001
C69.4 Ciliary body	0.000	0.998	0.001
C69.1 Cornea	0.000	0.998	0.001
E88.9 Metabolic disorder, unspecified	0.000	0.998	0.001
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.000	0.998	0.002
J33.0 Polyp of nasal cavity	0.000	0.998	0.002
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.002	0.998	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.001	0.998	0.000
C69.6 Orbit	0.000	0.998	0.001
E73.9 Lactose intolerance, unspecified	0.000	0.998	0.001
H69.0 Patulous Eustachian tube	0.001	0.998	0.001
L98.0 Pyogenic granuloma	0.000	0.998	0.002
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
O61.0 Failed medical induction of labour	0.000	0.998	0.002
R73.9 Hyperglycaemia, unspecified	0.000	0.998	0.002
Z54.0 Convalescence following surgery	0.002	0.998	0.000
L71 Rosacea	0.000	0.998	0.002
C50.3 Lower-inner quadrant of breast	0.000	0.998	0.002
H72.2 Other marginal perforations of tympanic membrane	0.000	0.998	0.002
O20.0 Threatened abortion	0.002	0.998	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.000	0.998	0.002
M79.10 Myalgia (Multiple sites)	0.000	0.998	0.001
C69.0 Conjunctiva	0.000	0.998	0.001
H72.8 Other perforations of tympanic membrane	0.000	0.998	0.002
L71.1 Rhinophyma	0.000	0.998	0.002
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.998	0.002
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
G93 Other disorders of brain	0.000	0.998	0.002
S12.91 Fracture of neck, part unspecified (open)	0.000	0.998	0.001
S82.01 Fracture of patella (open)	0.002	0.998	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.001	0.998	0.000
R76.8 Other specified abnormal immunological findings in serum	0.000	0.998	0.002
G71 Primary disorders of muscles	0.002	0.998	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.998	0.001
I33.0 Acute and subacute infective endocarditis	0.002	0.998	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.000	0.998	0.002
M79.88 Other specified soft tissue disorders (Other)	0.000	0.998	0.001
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.001
S12.2 Fracture of other specified cervical vertebra	0.000	0.998	0.001
S12.1 Fracture of second cervical vertebra	0.000	0.998	0.001
S70.1 Contusion of thigh	0.001	0.998	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.000	0.998	0.001
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.001	0.998	0.000
S02.51 Fracture of tooth (open)	0.001	0.998	0.000
J15.9 Bacterial pneumonia, unspecified	0.000	0.998	0.001
F25.9 Schizoaffective disorder, unspecified	0.001	0.999	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.000	0.999	0.001
S12 Fracture of neck	0.000	0.999	0.001
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.000	0.999	0.001
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.999	0.001
H73.8 Other specified disorders of tympanic membrane	0.000	0.999	0.001
L71.0 Perioral dermatitis	0.000	0.999	0.001
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
C92.0 Acute myeloid leukaemia	0.000	0.999	0.001
L71.8 Other rosacea	0.000	0.999	0.001
M17.0 Primary gonarthrosis, bilateral	0.001	0.999	0.000
M65.1 Other infective (teno)synovitis	0.000	0.999	0.001
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.999	0.001
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
H70.9 Mastoiditis, unspecified	0.000	0.999	0.001
M92.6 Juvenile osteochondrosis of tarsus	0.000	0.999	0.001
R76.0 Raised antibody titer	0.000	0.999	0.001
G93.7 Reye's syndrome	0.000	0.999	0.001
I42.2 Other hypertrophic cardiomyopathy	0.000	0.999	0.001
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.001	0.999	0.000
C53.9 Cervix uteri, unspecified	0.000	0.999	0.001
C69.9 Eye, unspecified	0.000	0.999	0.001
H69.8 Other specified disorders of Eustachian tube	0.001	0.999	0.001
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.001	0.999	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.001	0.999	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.001	0.999	0.000
S12.11 Fracture of second cervical vertebra (open)	0.000	0.999	0.001
G71.9 Primary disorder of muscle, unspecified	0.001	0.999	0.000
G71.8 Other primary disorders of muscles	0.001	0.999	0.000
G71.2 Congenital myopathies	0.001	0.999	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.999	0.001
T88.5 Other complications of anaesthesia	0.000	0.999	0.001
M65.83 Other synovitis and tenosynovitis (Forearm)	0.000	0.999	0.001
S12.21 Fracture of other specified cervical vertebra (open)	0.000	0.999	0.001
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.999	0.001
K75.9 Inflammatory liver disease, unspecified	0.000	0.999	0.001
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.001	0.999	0.000
S12.7 Multiple fractures of cervical spine	0.000	0.999	0.001
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.999	0.001
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
D47.1 Chronic myeloproliferative disease	0.000	0.999	0.001
H43.1 Vitreous haemorrhage	0.001	0.999	0.000
H72.1 Attic perforation of tympanic membrane	0.000	0.999	0.001
M02.90 Reactive arthropathy, unspecified (Multiple sites)	0.001	0.999	0.000
G93.5 Compression of brain	0.000	0.999	0.001
K22.9 Disease of oesophagus, unspecified	0.000	0.999	0.001
S12.8 Fracture of other parts of neck	0.000	0.999	0.001
T43.2 Other and unspecified antidepressants	0.000	0.999	0.001
M92 Other juvenile osteochondrosis	0.000	0.999	0.001
M65.19 Other infective (teno)synovitis (Site unspecified)	0.000	0.999	0.001
M65.18 Other infective (teno)synovitis (Other)	0.000	0.999	0.001
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations