TreeWAS – Variant ID: rs2346177

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M25.78 Osteophyte (Other)	0.288	0.712	0.000
M25.76 Osteophyte (Lower leg)	0.281	0.719	0.000
M25.7 Osteophyte	0.280	0.720	0.000
M25.77 Osteophyte (Ankle and foot)	0.260	0.740	0.000
M25.71 Osteophyte (Shoulder region)	0.248	0.752	0.000
M25.73 Osteophyte (Forearm)	0.222	0.778	0.000
M25.79 Osteophyte (Site unspecified)	0.207	0.793	0.000
M25.70 Osteophyte (Multiple sites)	0.201	0.799	0.000
M25.72 Osteophyte (Upper arm)	0.165	0.835	0.000
M25.74 Osteophyte (Hand)	0.073	0.927	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.057	0.943	0.000
M47.9 Spondylosis, unspecified	0.029	0.971	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.029	0.971	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.029	0.971	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.028	0.972	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.026	0.974	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.024	0.976	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.023	0.977	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.022	0.977	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.021	0.979	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.020	0.979	0.000
S64 Injury of nerves at wrist and hand level	0.000	0.988	0.012
S02.60 Fracture of mandible (closed)	0.011	0.989	0.000
S64.3 Injury of digital nerve of thumb	0.000	0.989	0.011
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.989	0.011
S64.1 Injury of median nerve at wrist and hand level	0.000	0.990	0.010
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.990	0.010
S89.9 Unspecified injury of lower leg	0.000	0.990	0.010
S64.4 Injury of digital nerve of other finger	0.000	0.991	0.009
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.991	0.009
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.991	0.009
S64.8 Injury of other nerves at wrist and hand level	0.000	0.991	0.009
M47.96 Spondylosis, unspecified (Lumbar region)	0.007	0.993	0.000
T92 Sequelae of injuries of upper limb	0.007	0.993	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.007	0.993	0.000
T92.1 Sequelae of fracture of arm	0.007	0.993	0.000
T92.0 Sequelae of open wound of upper limb	0.007	0.993	0.000
S68 Traumatic amputation of wrist and hand	0.000	0.993	0.007
S60-S69 Injuries to the wrist and hand	0.000	0.993	0.007
S65 Injury of blood vessels at wrist and hand level	0.000	0.993	0.007
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.993	0.007
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.994	0.006
T92.8 Sequelae of other specified injuries of upper limb	0.006	0.994	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.994	0.006
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.994	0.006
T92.2 Sequelae of fracture at wrist and hand level	0.006	0.994	0.000
J38.7 Other diseases of larynx	0.006	0.994	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.006	0.994	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.994	0.006
M47 Spondylosis	0.006	0.994	0.000
S63.0 Dislocation of wrist	0.000	0.994	0.006
S65.1 Injury of radial artery at wrist and hand level	0.000	0.994	0.006
S65.5 Injury of blood vessel(s) of other finger	0.000	0.994	0.006
S68.0 Traumatic amputation of thumb (complete)(partial)	0.000	0.994	0.006
S63.6 Sprain and strain of finger(s)	0.000	0.994	0.006
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.994	0.006
G31.8 Other specified degenerative diseases of nervous system	0.000	0.994	0.006
T92.4 Sequelae of injury of nerve of upper limb	0.006	0.994	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.994	0.006
S65.0 Injury of ulnar artery at wrist and hand level	0.000	0.994	0.005
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.995	0.005
M25.96 Joint disorder, unspecified (Lower leg)	0.005	0.995	0.000
D53.9 Nutritional anaemia, unspecified	0.005	0.995	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.005	0.995	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.005	0.995	0.000
M25 Other joint disorders, not elsewhere classified	0.005	0.995	0.000
M25.9 Joint disorder, unspecified	0.005	0.995	0.000
M47.2 Other spondylosis with radiculopathy	0.005	0.995	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.005	0.995	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.000	0.995	0.005
S68.8 Traumatic amputation of other parts of wrist and hand	0.000	0.995	0.005
S68.4 Traumatic amputation of hand at wrist level	0.000	0.995	0.005
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.000	0.995	0.005
S63.5 Sprain and strain of wrist	0.000	0.995	0.005
M25.91 Joint disorder, unspecified (Shoulder region)	0.005	0.995	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.000	0.995	0.005
S65.8 Injury of other blood vessels at wrist and hand level	0.000	0.995	0.005
S65.7 Injury of multiple blood vessels at wrist and hand level	0.000	0.995	0.005
S65.4 Injury of blood vessel(s) of thumb	0.000	0.995	0.005
S65.3 Injury of deep palmar arch	0.000	0.995	0.005
S65.2 Injury of superficial palmar arch	0.000	0.995	0.005
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.995	0.005
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.995	0.005
S02.6 Fracture of mandible	0.005	0.995	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.995	0.005
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.995	0.005
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.995	0.005
T92.9 Sequelae of unspecified injury of upper limb	0.005	0.995	0.000
S63.1 Dislocation finger	0.000	0.995	0.005
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.995	0.005
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.005	0.995	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.995	0.005
S63.7 Sprain and strain of other and unspecified parts of hand	0.000	0.995	0.005
M47.0 Anterior spinal and vertebral artery compression syndromes	0.004	0.995	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.995	0.005
S67 Crushing injury of wrist and hand	0.000	0.995	0.004
Z47.8 Other specified orthopaedic follow-up care	0.004	0.996	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.000	0.996	0.004
S63.2 Multiple dislocations of fingers	0.000	0.996	0.004
M25.92 Joint disorder, unspecified (Upper arm)	0.004	0.996	0.000
G93.2 Benign intracranial hypertension	0.000	0.996	0.004
N36.0 Urethral fistula	0.000	0.996	0.004
M25.2 Flail joint	0.004	0.996	0.000
M25.1 Fistula of joint	0.004	0.996	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.996	0.004
S89 Other and unspecified injuries of lower leg	0.000	0.996	0.004
M25.98 Joint disorder, unspecified (Other)	0.004	0.996	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.004	0.996	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.004	0.996	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.004	0.996	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.004	0.996	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.004	0.996	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.004	0.996	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.004	0.996	0.000
M54.16 Radiculopathy (Lumbar region)	0.004	0.996	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.004	0.996	0.000
S02.61 Fracture of mandible (open)	0.004	0.996	0.000
M25.0 Haemarthrosis	0.004	0.996	0.000
N36.1 Urethral diverticulum	0.000	0.996	0.004
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.004	0.996	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.996	0.004
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.996	0.004
N36 Other disorders of urethra	0.000	0.996	0.004
S62.50 Fracture of thumb (closed)	0.004	0.996	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.000	0.996	0.003
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.004	0.996	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.003	0.996	0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.003	0.996	0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.003	0.996	0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.003	0.996	0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.003	0.996	0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.003	0.996	0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.003	0.996	0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.003	0.996	0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.003	0.996	0.000
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.003	0.996	0.000
G25.0 Essential tremor	0.004	0.996	0.000
L40.0 Psoriasis vulgaris	0.003	0.997	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.003	0.997	0.000
M25.94 Joint disorder, unspecified (Hand)	0.003	0.997	0.000
N36.2 Urethral caruncle	0.000	0.997	0.003
Q87.4 Marfan's syndrome	0.003	0.997	0.000
N36.8 Other specified disorders of urethra	0.000	0.997	0.003
Z32.0 Pregnancy, not (yet) confirmed	0.003	0.997	0.000
S69 Other and unspecified injuries of wrist and hand	0.000	0.997	0.003
S61 Open wound of wrist and hand	0.000	0.997	0.003
N36.9 Urethral disorder, unspecified	0.000	0.997	0.003
M25.19 Fistula of joint (Site unspecified)	0.003	0.997	0.000
M25.18 Fistula of joint (Other)	0.003	0.997	0.000
M25.17 Fistula of joint (Ankle and foot)	0.003	0.997	0.000
M25.16 Fistula of joint (Lower leg)	0.003	0.997	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.003	0.997	0.000
M25.14 Fistula of joint (Hand)	0.003	0.997	0.000
M25.13 Fistula of joint (Forearm)	0.003	0.997	0.000
M25.12 Fistula of joint (Upper arm)	0.003	0.997	0.000
M25.11 Fistula of joint (Shoulder region)	0.003	0.997	0.000
M25.10 Fistula of joint (Multiple sites)	0.003	0.997	0.000
M25.29 Flail joint (Site unspecified)	0.003	0.997	0.000
M25.28 Flail joint (Other)	0.003	0.997	0.000
M25.27 Flail joint (Ankle and foot)	0.003	0.997	0.000
M25.26 Flail joint (Lower leg)	0.003	0.997	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.003	0.997	0.000
M25.24 Flail joint (Hand)	0.003	0.997	0.000
M25.23 Flail joint (Forearm)	0.003	0.997	0.000
M25.22 Flail joint (Upper arm)	0.003	0.997	0.000
M25.21 Flail joint (Shoulder region)	0.003	0.997	0.000
M25.20 Flail joint (Multiple sites)	0.003	0.997	0.000
S89.7 Multiple injuries of lower leg	0.000	0.997	0.003
S89.1 Other specified injuries of lower leg	0.000	0.997	0.003
S89.0 Multiple injuries of lower leg	0.000	0.997	0.003
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.997	0.003
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.997	0.003
S61.0 Open wound of finger(s) without damage to nail	0.000	0.997	0.003
M25.3 Other instability of joint	0.003	0.997	0.000
M47.1 Other spondylosis with myelopathy	0.003	0.997	0.000
S89.8 Other specified injuries of lower leg	0.000	0.997	0.003
M25.09 Haemarthrosis (Site unspecified)	0.003	0.997	0.000
M25.08 Haemarthrosis (Other)	0.003	0.997	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.003	0.997	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.003	0.997	0.000
M25.04 Haemarthrosis (Hand)	0.003	0.997	0.000
M25.03 Haemarthrosis (Forearm)	0.003	0.997	0.000
M25.02 Haemarthrosis (Upper arm)	0.003	0.997	0.000
M25.01 Haemarthrosis (Shoulder region)	0.003	0.997	0.000
M25.00 Haemarthrosis (Multiple sites)	0.003	0.997	0.000
N70 Salpingitis and oophoritis	0.003	0.997	0.000
N70.1 Chronic salpingitis and oophoritis	0.003	0.997	0.000
M25.34 Other instability of joint (Hand)	0.003	0.997	0.000
D53 Other nutritional anaemias	0.003	0.997	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.003	0.997	0.000
N39.4 Other specified urinary incontinence	0.003	0.997	0.000
N80.8 Other endometriosis	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.003	0.997	0.000
G31.0 Circumscribed brain atrophy	0.000	0.997	0.003
M25.06 Haemarthrosis (Lower leg)	0.003	0.997	0.000
G93.9 Disorder of brain, unspecified	0.000	0.997	0.003
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.003	0.997	0.000
H57.0 Anomalies of pupillary function	0.000	0.997	0.003
M54.1 Radiculopathy	0.003	0.997	0.000
M54.19 Radiculopathy (Site unspecified)	0.003	0.997	0.000
S69.7 Multiple injuries of wrist and hand	0.000	0.997	0.002
M25.39 Other instability of joint (Site unspecified)	0.002	0.997	0.000
M25.38 Other instability of joint (Other)	0.002	0.997	0.000
M25.36 Other instability of joint (Lower leg)	0.002	0.997	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.002	0.997	0.000
M25.32 Other instability of joint (Upper arm)	0.002	0.997	0.000
M25.30 Other instability of joint (Multiple sites)	0.002	0.997	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.997	0.002
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.002	0.997	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.002	0.997	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.002	0.997	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.002	0.997	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.002	0.997	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.002	0.997	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.002	0.997	0.000
S61.7 Multiple open wounds of wrist and hand	0.000	0.998	0.002
M77.02 Medial epicondylitis (Upper arm)	0.002	0.998	0.000
L05.9 Pilonidal cyst without abscess	0.002	0.998	0.000
D53.8 Other specified nutritional anaemias	0.002	0.998	0.000
D53.2 Scorbutic anaemia	0.002	0.998	0.000
D53.0 Protein deficiency anaemia	0.002	0.998	0.000
N90.4 Leukoplakia of vulva	0.002	0.998	0.000
W11.6 Industrial and construction area	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.998	0.002
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
M25.33 Other instability of joint (Forearm)	0.002	0.998	0.000
M25.4 Effusion of joint	0.002	0.998	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.998	0.002
M54.14 Radiculopathy (Thoracic region)	0.002	0.998	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.998	0.002
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.998	0.002
M54.15 Radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
S69.8 Other specified injuries of wrist and hand	0.000	0.998	0.002
N70.0 Acute salpingitis and oophoritis	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.002	0.998	0.000
N42.8 Other specified disorders of prostate	0.000	0.998	0.002
I84.7 Unspecified thrombosed haemorrhoids	0.002	0.998	0.000
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
M25.42 Effusion of joint (Upper arm)	0.002	0.998	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.002	0.998	0.000
I50.0 Congestive heart failure	0.002	0.998	0.000
N36.3 Prolapsed urethral mucosa	0.000	0.998	0.002
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
S60 Superficial injury of wrist and hand	0.000	0.998	0.002
I47.2 Ventricular tachycardia	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.002	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.998	0.002
G93 Other disorders of brain	0.000	0.998	0.002
M25.41 Effusion of joint (Shoulder region)	0.002	0.998	0.000
S62.5 Fracture of thumb	0.001	0.998	0.001
M25.37 Other instability of joint (Ankle and foot)	0.002	0.998	0.000
A41.9 Septicaemia, unspecified	0.000	0.998	0.002
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
M25.47 Effusion of joint (Ankle and foot)	0.002	0.998	0.000
M25.43 Effusion of joint (Forearm)	0.002	0.998	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
G93.4 Encephalopathy, unspecified	0.000	0.998	0.002
W44.0 Home	0.002	0.998	0.000
M25.40 Effusion of joint (Multiple sites)	0.002	0.998	0.000
N48.4 Impotence of organic origin	0.000	0.998	0.002
X63.0 Home	0.002	0.998	0.000
M25.49 Effusion of joint (Site unspecified)	0.002	0.998	0.000
M25.48 Effusion of joint (Other)	0.002	0.998	0.000
J18.0 Bronchopneumonia, unspecified	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
W22.9 Unspecified place	0.002	0.998	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
S52.20 Fracture of shaft of ulna (closed)	0.002	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.002	0.998	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.002	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.998	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.002	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.002	0.998	0.000
G93.8 Other specified disorders of brain	0.000	0.998	0.002
S62.7 Multiple fractures of fingers	0.000	0.998	0.002
S69.9 Unspecified injury of wrist and hand	0.000	0.998	0.002
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.998	0.000
S62 Fracture at wrist and hand level	0.000	0.998	0.002
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.002	0.998	0.000
M25.31 Other instability of joint (Shoulder region)	0.001	0.998	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
G93.7 Reye's syndrome	0.000	0.998	0.002
S60.1 Contusion of finger(s) with damage to nail	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.000	0.998	0.002
C18.2 Ascending colon	0.002	0.998	0.000
L94.0 Localised scleroderma [morphea]	0.000	0.998	0.002
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.998	0.002
S62.71 Multiple fractures of fingers (open)	0.000	0.998	0.002
Z51.2 Other chemotherapy	0.002	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.001	0.998	0.000
M77.0 Medial epicondylitis	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.001	0.998	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.998	0.002
C44.2 Skin of ear and external auricular canal	0.002	0.998	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Z92.1 Personal history of long-term (current) use of anticoagulants	0.002	0.998	0.000
M47.8 Other spondylosis	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.000	0.998	0.002
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.998	0.002
N13.5 Kinking and stricture of ureter without hydronephrosis	0.002	0.998	0.000
F03 Unspecified dementia	0.002	0.998	0.000
M47.89 Other spondylosis (Site unspecified)	0.002	0.998	0.000
M47.86 Other spondylosis (Lumbar region)	0.002	0.998	0.000
M54.12 Radiculopathy (Cervical region)	0.001	0.998	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.000	0.998	0.001
S60.2 Contusion of other parts of wrist and hand	0.000	0.998	0.001
S62.1 Fracture of other carpal bone(s)	0.000	0.998	0.001
Z47.9 Orthopaedic follow-up care, unspecified	0.002	0.998	0.000
M25.44 Effusion of joint (Hand)	0.001	0.998	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.998	0.001
M81.98 Osteoporosis, unspecified (Other)	0.000	0.998	0.002
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.998	0.001
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.998	0.001
D86 Sarcoidosis	0.002	0.998	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.001	0.998	0.000
E23.0 Hypopituitarism	0.001	0.999	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.001	0.999	0.000
S43.1 Dislocation of acromioclavicular joint	0.001	0.999	0.000
W22.3 Sports and athletics area	0.001	0.999	0.000
S60.0 Contusion of finger(s) without damage to nail	0.000	0.999	0.001
M77.09 Medial epicondylitis (Site unspecified)	0.001	0.999	0.000
M77.08 Medial epicondylitis-Other	0.001	0.999	0.000
M77.07 Medial epicondylitis-Ankle/Foot	0.001	0.999	0.000
M77.06 Medial epicondylitis (Lower leg)	0.001	0.999	0.000
M77.05 Medial epicondylitis (Pelvic region and thigh)	0.001	0.999	0.000
M77.04 Medial epicondylitis-Hand	0.001	0.999	0.000
M77.03 Medial epicondylitis-Forearm	0.001	0.999	0.000
M77.01 Medial epicondylitis-Shldr region	0.001	0.999	0.000
M77.00 Medial epicondylitis (Multiple sites)	0.001	0.999	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.999	0.001
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
J03.9 Acute tonsillitis, unspecified	0.001	0.999	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.999	0.001
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
S62.51 Fracture of thumb (open)	0.001	0.999	0.001
Q18.0 Sinus, fistula and cyst of branchial cleft	0.000	0.999	0.001
W11.4 Street and highway	0.001	0.999	0.000
Z47 Other orthopaedic follow-up care	0.001	0.999	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.999	0.001
C88.0 Waldenstrom's macroglobulinaemia	0.001	0.999	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.999	0.001
D16.4 Bones of skull and face	0.000	0.999	0.001
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.001	0.999	0.000
G93.5 Compression of brain	0.000	0.999	0.001
N60.3 Fibrosclerosis of breast	0.000	0.999	0.001
M47.85 Other spondylosis (Thoracolumbar region)	0.001	0.999	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.999	0.001
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.999	0.001
H72.0 Central perforation of tympanic membrane	0.001	0.999	0.000
S62.4 Multiple fractures of metacarpal bones	0.000	0.999	0.001
M25.45 Effusion of joint (Pelvic region and thigh)	0.001	0.999	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.001	0.999	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.001	0.999	0.000
S52.21 Fracture of shaft of ulna (open)	0.001	0.999	0.000
F06.7 Mild cognitive disorder	0.001	0.999	0.000
K65.9 Peritonitis, unspecified	0.001	0.999	0.000
Z44.3 Fitting and adjustment of external breast prosthesis	0.000	0.999	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
L05 Pilonidal cyst	0.001	0.999	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.999	0.000
W11 Fall on and from ladder	0.001	0.999	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.999	0.001
H91.8 Other specified hearing loss	0.001	0.999	0.000
L05.0 Pilonidal cyst with abscess	0.001	0.999	0.000
N99.2 Postprocedural adhesions of vagina	0.000	0.999	0.001
W51.9 Unspecified place	0.001	0.999	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.001	0.999	0.000
R25.2 Cramp and spasm	0.000	0.999	0.001
S52.2 Fracture of shaft of ulna	0.001	0.999	0.000
S50.9 Superficial injury of forearm, unspecified	0.001	0.999	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.999	0.001
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.999	0.001
M77.1 Lateral epicondylitis	0.001	0.999	0.000
W22 Striking against or struck by other objects	0.001	0.999	0.000
M10.99 Gout, unspecified (Site unspecified)	0.001	0.999	0.000
N99.0 Postprocedural renal failure	0.000	0.999	0.001
M47.84 Other spondylosis (Thoracic region)	0.001	0.999	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.999	0.000
D89.3 Immune reconstitution syndrome	0.001	0.999	0.000
S62.2 Fracture of first metacarpal bone	0.000	0.999	0.001
W11.9 Unspecified place	0.001	0.999	0.000
W11.8 Other specified place	0.001	0.999	0.000
W11.0 Home	0.001	0.999	0.000
W11.7 Farm	0.001	0.999	0.000
W11.3 Sports and athletics area	0.001	0.999	0.000
W11.2 School, other institution and public administrative area	0.001	0.999	0.000
W11.1 Residential institution	0.001	0.999	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.999	0.001
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M77.13 Lateral epicondylitis-Forearm	0.001	0.999	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.999	0.000
N76.4 Abscess of vulva	0.001	0.999	0.000
Q28.3 Other malformations of cerebral vessels	0.001	0.999	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
D26.9 Uterus, unspecified	0.000	0.999	0.001
D86.8 Sarcoidosis of other and combined sites	0.001	0.999	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.999	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
N64.1 Fat necrosis of breast	0.000	0.999	0.001
Q12.0 Congenital cataract	0.000	0.999	0.001
R56.8 Other and unspecified convulsions	0.000	0.999	0.001
M77.19 Lateral epicondylitis (Site unspecified)	0.001	0.999	0.000
M77.18 Lateral epicondylitis-Other	0.001	0.999	0.000
M77.17 Lateral epicondylitis-Ankle/Foot	0.001	0.999	0.000
M77.16 Lateral epicondylitis (Lower leg)	0.001	0.999	0.000
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.001	0.999	0.000
M77.14 Lateral epicondylitis-Hand	0.001	0.999	0.000
M77.11 Lateral epicondylitis-Shldr region	0.001	0.999	0.000
M77.10 Lateral epicondylitis (Multiple sites)	0.001	0.999	0.000
D82.1 Di George's syndrome	0.001	0.999	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.000
D86.3 Sarcoidosis of skin	0.001	0.999	0.000
W22.8 Other specified place	0.001	0.999	0.000
W22.6 Industrial and construction area	0.001	0.999	0.000
W22.4 Street and highway	0.001	0.999	0.000
W22.0 Home	0.001	0.999	0.000
W22.7 Farm	0.001	0.999	0.000
W22.1 Residential institution	0.001	0.999	0.000
D83 Common variable immunodeficiency	0.001	0.999	0.000
D82 Immunodeficiency associated with other major defects	0.001	0.999	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
D80-D89 Certain disorders involving the immune mechanism	0.001	0.999	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.001	0.999	0.000
S52.01 Fracture of upper end of ulna (open)	0.001	0.999	0.000
S62.21 Fracture of first metacarpal bone (open)	0.000	0.999	0.001
W11.09 Fall on and from ladder; Home; During unspecified activity	0.001	0.999	0.000
W11.03 Fall on and from ladder; Home; While engaged in other types of work	0.001	0.999	0.000
W11.82 Fall on and from ladder; Other specified places; While working for income	0.001	0.999	0.000
W11.99 Fall on and from ladder; Unspecified place; During unspecified activity	0.001	0.999	0.000
D86.9 Sarcoidosis, unspecified	0.001	0.999	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.999	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.999	0.001
O73.0 Retained placenta, without haemorrhage	0.000	0.999	0.001
W28.9 Unspecified place	0.001	0.999	0.000
X78.0 Home	0.000	0.999	0.001
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.001	0.999	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.999	0.001
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.999	0.001
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.001	0.999	0.000
I47.0 Reentry ventricular arrhythmia	0.001	0.999	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.001	0.999	0.000
Q18.1 Preauricular sinus and cyst	0.000	0.999	0.001
Q79.6 Ehlers-Danlos syndrome	0.001	0.999	0.000
W11.5 Trade and service area	0.001	0.999	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.001	0.999	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.999	0.001
W22.09 Striking against or struck by other objects; Home; During unspecified activity	0.001	0.999	0.000
W22.03 Striking against or struck by other objects; Home; While engaged in other types of work	0.001	0.999	0.000
W22.41 Striking against or struck by other objects; Street and highway;While engaged in leisure activity	0.001	0.999	0.000
W22.62 Striking against or struck by other objects; Industrial and construction area ;While working for income	0.001	0.999	0.000
W22.88 Striking against or struck by other objects; Other specified places ;While engaged in other specified activities	0.001	0.999	0.000
D47.2 Monoclonal gammopathy	0.001	0.999	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
E23.2 Diabetes insipidus	0.001	0.999	0.000
E61.1 Iron deficiency	0.001	0.999	0.000
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.001	0.999	0.000
S50.1 Contusion of other and unspecified parts of forearm	0.001	0.999	0.000
D81 Combined immunodeficiencies	0.001	0.999	0.000
D80 Immunodeficiency with predominantly antibody defects	0.001	0.999	0.000
Q18 Other congenital malformations of face and neck	0.000	0.999	0.001
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.001	0.999	0.000
M43.62 Torticollis-Cervical	0.001	0.999	0.000
B02.2 Zoster with other nervous system involvement	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
F01.9 Vascular dementia, unspecified	0.001	0.999	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.001	0.999	0.000
F06.5 Organic dissociative disorder	0.001	0.999	0.000
F06.4 Organic anxiety disorder	0.001	0.999	0.000
F06.3 Organic mood [affective] disorders	0.001	0.999	0.000
F06.1 Organic catatonic disorder	0.001	0.999	0.000
F06.0 Organic hallucinosis	0.001	0.999	0.000
K02.8 Other dental caries	0.000	0.999	0.001
S51.0 Open wound of elbow	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations