TreeWAS – Variant ID: rs2373115

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M20.1 Hallux valgus (acquired)	0.000	0.112	0.888
M20 Acquired deformities of fingers and toes	0.000	0.159	0.841
M20.2 Hallux rigidus	0.000	0.186	0.814
M20.5 Other deformities of toe(s) (acquired)	0.000	0.194	0.806
F10 Mental and behavioural disorders due to use of alcohol	0.679	0.321	0.000
F10.2 Dependence syndrome	0.675	0.325	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.333	0.667
F10.1 Harmful use	0.667	0.333	0.000
F10.3 Withdrawal state	0.648	0.352	0.000
F10.0 Acute intoxication	0.641	0.359	0.000
F10.5 Psychotic disorder	0.538	0.462	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.464	0.536
F10.9 Unspecified mental and behavioural disorder	0.490	0.510	0.000
F10.8 Other mental and behavioural disorders	0.487	0.513	0.000
F10.7 Residual and late-onset psychotic disorder	0.487	0.513	0.000
M20.0 Deformity of finger(s)	0.000	0.526	0.474
M20.3 Other deformity of hallux (acquired)	0.000	0.547	0.453
F10.4 Withdrawal state with delirium	0.448	0.552	0.000
F10.6 Amnesic syndrome	0.408	0.592	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.113	0.887	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.087	0.913	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.082	0.918	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.081	0.919	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.081	0.919	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.081	0.919	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.081	0.919	0.000
F11 Mental and behavioural disorders due to use of opioids	0.076	0.924	0.000
F15.1 Harmful use	0.068	0.931	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.068	0.932	0.000
F15.9 Unspecified mental and behavioural disorder	0.063	0.937	0.000
F15.8 Other mental and behavioural disorders	0.063	0.937	0.000
F15.7 Residual and late-onset psychotic disorder	0.063	0.937	0.000
F15.6 Amnesic syndrome	0.063	0.937	0.000
F15.5 Psychotic disorder	0.063	0.937	0.000
F15.4 Withdrawal state with delirium	0.063	0.937	0.000
F15.3 Withdrawal state	0.063	0.937	0.000
F15.2 Dependence syndrome	0.063	0.937	0.000
F15.0 Acute intoxication	0.063	0.937	0.000
F19.2 Dependence syndrome	0.060	0.939	0.000
F19.9 Unspecified mental and behavioural disorder	0.059	0.941	0.000
F19.8 Other mental and behavioural disorders	0.059	0.941	0.000
F19.7 Residual and late-onset psychotic disorder	0.059	0.941	0.000
F19.6 Amnesic syndrome	0.059	0.941	0.000
F19.5 Psychotic disorder	0.059	0.941	0.000
F19.4 Withdrawal state with delirium	0.059	0.941	0.000
F19.3 Withdrawal state	0.059	0.941	0.000
F19.0 Acute intoxication	0.059	0.941	0.000
F13.9 Unspecified mental and behavioural disorder	0.058	0.941	0.000
F13.8 Other mental and behavioural disorders	0.058	0.941	0.000
F13.7 Residual and late-onset psychotic disorder	0.058	0.941	0.000
F13.6 Amnesic syndrome	0.058	0.941	0.000
F13.5 Psychotic disorder	0.058	0.941	0.000
F13.4 Withdrawal state with delirium	0.058	0.941	0.000
F13.3 Withdrawal state	0.058	0.941	0.000
F13.2 Dependence syndrome	0.058	0.941	0.000
F13.1 Harmful use	0.058	0.941	0.000
F13.0 Acute intoxication	0.058	0.941	0.000
F14.9 Unspecified mental and behavioural disorder	0.058	0.941	0.000
F14.8 Other mental and behavioural disorders	0.058	0.941	0.000
F14.7 Residual and late-onset psychotic disorder	0.058	0.941	0.000
F14.6 Amnesic syndrome	0.058	0.941	0.000
F14.5 Psychotic disorder	0.058	0.941	0.000
F14.4 Withdrawal state with delirium	0.058	0.941	0.000
F14.3 Withdrawal state	0.058	0.941	0.000
F14.2 Dependence syndrome	0.058	0.941	0.000
F14.1 Harmful use	0.058	0.941	0.000
F14.0 Acute intoxication	0.058	0.941	0.000
F16.9 Unspecified mental and behavioural disorder	0.058	0.941	0.000
F16.8 Other mental and behavioural disorders	0.058	0.941	0.000
F16.7 Residual and late-onset psychotic disorder	0.058	0.941	0.000
F16.6 Amnesic syndrome	0.058	0.941	0.000
F16.5 Psychotic disorder	0.058	0.941	0.000
F16.4 Withdrawal state with delirium	0.058	0.941	0.000
F16.3 Withdrawal state	0.058	0.941	0.000
F16.2 Dependence syndrome	0.058	0.941	0.000
F16.1 Harmful use	0.058	0.941	0.000
F16.0 Acute intoxication	0.058	0.941	0.000
F18.9 Unspecified mental and behavioural disorder	0.058	0.941	0.000
F18.8 Other mental and behavioural disorders	0.058	0.941	0.000
F18.7 Residual and late-onset psychotic disorder	0.058	0.941	0.000
F18.6 Amnesic syndrome	0.058	0.941	0.000
F18.5 Psychotic disorder	0.058	0.941	0.000
F18.4 Withdrawal state with delirium	0.058	0.941	0.000
F18.3 Withdrawal state	0.058	0.941	0.000
F18.2 Dependence syndrome	0.058	0.941	0.000
F18.1 Harmful use	0.058	0.941	0.000
F18.0 Acute intoxication	0.058	0.941	0.000
F19.1 Harmful use	0.058	0.942	0.000
F11.9 Unspecified mental and behavioural disorder	0.054	0.945	0.000
F11.8 Other mental and behavioural disorders	0.054	0.945	0.000
F11.7 Residual and late-onset psychotic disorder	0.054	0.945	0.000
F11.6 Amnesic syndrome	0.054	0.945	0.000
F11.5 Psychotic disorder	0.054	0.945	0.000
F11.4 Withdrawal state with delirium	0.054	0.945	0.000
F11.3 Withdrawal state	0.054	0.945	0.000
F11.1 Harmful use	0.054	0.945	0.000
F11.0 Acute intoxication	0.054	0.945	0.000
F12.9 Unspecified mental and behavioural disorder	0.049	0.951	0.000
F12.8 Other mental and behavioural disorders	0.049	0.951	0.000
F12.7 Residual and late-onset psychotic disorder	0.049	0.951	0.000
F12.6 Amnesic syndrome	0.049	0.951	0.000
F12.5 Psychotic disorder	0.049	0.951	0.000
F12.4 Withdrawal state with delirium	0.049	0.951	0.000
F12.3 Withdrawal state	0.049	0.951	0.000
F12.0 Acute intoxication	0.049	0.951	0.000
F11.2 Dependence syndrome	0.049	0.951	0.000
F12.2 Dependence syndrome	0.044	0.956	0.000
F12.1 Harmful use	0.043	0.957	0.000
D73.0 Hyposplenism	0.032	0.968	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.027	0.973	0.000
D73 Diseases of spleen	0.027	0.973	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.026	0.974	0.000
D73.9 Disease of spleen, unspecified	0.023	0.977	0.000
D70 Agranulocytosis	0.022	0.978	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.022	0.978	0.000
D73.4 Cyst of spleen	0.020	0.980	0.000
D73.3 Abscess of spleen	0.019	0.980	0.000
D73.2 Chronic congestive splenomegaly	0.019	0.980	0.000
D73.1 Hypersplenism	0.019	0.980	0.000
D73.8 Other diseases of spleen	0.019	0.981	0.000
F17.9 Unspecified mental and behavioural disorder	0.018	0.981	0.000
F17.8 Other mental and behavioural disorders	0.018	0.981	0.000
F17.7 Residual and late-onset psychotic disorder	0.018	0.981	0.000
F17.6 Amnesic syndrome	0.018	0.981	0.000
F17.5 Psychotic disorder	0.018	0.981	0.000
F17.4 Withdrawal state with delirium	0.018	0.981	0.000
F17.3 Withdrawal state	0.018	0.981	0.000
F17.0 Acute intoxication	0.018	0.981	0.000
D72 Other disorders of white blood cells	0.018	0.982	0.000
G43.9 Migraine, unspecified	0.018	0.982	0.000
D73.5 Infarction of spleen	0.017	0.983	0.000
D72.8 Other specified disorders of white blood cells	0.016	0.984	0.000
D74 Methaemoglobinaemia	0.016	0.984	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.016	0.984	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.016	0.984	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.014	0.986	0.000
D72.9 Disorder of white blood cells, unspecified	0.013	0.986	0.000
D72.0 Genetic anomalies of leukocytes	0.013	0.986	0.000
D72.1 Eosinophilia	0.013	0.987	0.000
D74.9 Methaemoglobinaemia, unspecified	0.011	0.988	0.000
D74.8 Other methaemoglobinaemias	0.011	0.988	0.000
D74.0 Congenital methaemoglobinaemia	0.011	0.988	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.012	0.988	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.011	0.989	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.011	0.989	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.989	0.011
M35.3 Polymyalgia rheumatica	0.000	0.990	0.010
D76.2 Haemophagocytic syndrome, infection-associated	0.010	0.990	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.010	0.990	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.010	0.990	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.990	0.010
H53.1 Subjective visual disturbances	0.010	0.990	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.010	0.990	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.010	0.990	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.009	0.991	0.000
D80-D89 Certain disorders involving the immune mechanism	0.009	0.991	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.009	0.991	0.000
D75 Other diseases of blood and blood-forming organs	0.008	0.991	0.001
H60.9 Otitis externa, unspecified	0.008	0.992	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.008	0.992	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.008	0.992	0.000
D89.3 Immune reconstitution syndrome	0.008	0.992	0.000
D89.1 Cryoglobulinaemia	0.008	0.992	0.000
D76.3 Other histiocytosis syndromes	0.008	0.992	0.000
H60 Otitis externa	0.008	0.992	0.000
F17.2 Dependence syndrome	0.008	0.992	0.000
H60.8 Other otitis externa	0.007	0.992	0.000
D82 Immunodeficiency associated with other major defects	0.007	0.993	0.000
M35 Other systemic involvement of connective tissue	0.000	0.993	0.007
D75.0 Familial erythrocytosis	0.007	0.993	0.000
D55-D59 Haemolytic anaemias	0.007	0.993	0.000
D80 Immunodeficiency with predominantly antibody defects	0.007	0.993	0.000
M20-M25 Other joint disorders	0.000	0.993	0.007
D81 Combined immunodeficiencies	0.007	0.993	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.007	0.993	0.000
H60.3 Other infective otitis externa	0.007	0.993	0.000
D83 Common variable immunodeficiency	0.007	0.993	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.993	0.007
D84 Other immunodeficiencies	0.007	0.993	0.000
I73 Other peripheral vascular diseases	0.000	0.993	0.007
D69.6 Thrombocytopenia, unspecified	0.007	0.993	0.000
H60.4 Cholesteatoma of external ear	0.007	0.993	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.006	0.993	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.006	0.994	0.000
H60.1 Cellulitis of external ear	0.006	0.994	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.006	0.994	0.000
D58 Other hereditary haemolytic anaemias	0.006	0.994	0.000
D69 Purpura and other haemorrhagic conditions	0.006	0.994	0.000
D82.1 Di George's syndrome	0.006	0.994	0.000
H60.0 Abscess of external ear	0.006	0.994	0.000
M32 Systemic lupus erythematosus	0.000	0.994	0.006
M33 Dermatopolymyositis	0.000	0.994	0.006
H60.2 Malignant otitis externa	0.006	0.994	0.000
O46.9 Antepartum haemorrhage, unspecified	0.006	0.994	0.000
H21.8 Other specified disorders of iris and ciliary body	0.006	0.994	0.000
G35 Multiple sclerosis	0.006	0.994	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.005	0.994	0.000
I73.0 Raynaud's syndrome	0.000	0.994	0.006
D86 Sarcoidosis	0.006	0.994	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.994	0.006
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.006	0.994	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.005	0.994	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.005	0.994	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.005	0.994	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.005	0.994	0.000
D82.2 Immunodeficiency with short-limbed stature	0.005	0.994	0.000
D82.0 Wiskott-Aldrich syndrome	0.005	0.994	0.000
H21 Other disorders of iris and ciliary body	0.006	0.994	0.000
H60.5 Acute otitis externa, non-infective	0.005	0.994	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.005	0.994	0.000
E10.9 Without complications	0.000	0.994	0.006
M35.2 Behcet's disease	0.000	0.994	0.005
D58.9 Hereditary haemolytic anaemia, unspecified	0.005	0.994	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.995	0.005
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.995	0.005
M35.5 Multifocal fibrosclerosis	0.000	0.995	0.005
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.995	0.005
H21.5 Other adhesions and disruptions of iris and ciliary body	0.005	0.995	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.995	0.005
I73.8 Other specified peripheral vascular diseases	0.000	0.995	0.005
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.995	0.005
D57 Sickle-cell disorders	0.005	0.995	0.000
D55 Anaemia due to enzyme disorders	0.005	0.995	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.005	0.995	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.005	0.995	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.005	0.995	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.005	0.995	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.005	0.995	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.005	0.995	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.005	0.995	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.005	0.995	0.000
M79.8 Other specified soft tissue disorders	0.005	0.995	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.005	0.995	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.005	0.995	0.000
D81.9 Combined immunodeficiency, unspecified	0.005	0.995	0.000
D81.8 Other combined immunodeficiencies	0.005	0.995	0.000
D81.7 Major histocompatibility complex class II deficiency	0.005	0.995	0.000
D81.6 Major histocompatibility complex class I deficiency	0.005	0.995	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.005	0.995	0.000
D81.4 Nezelof's syndrome	0.005	0.995	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.005	0.995	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.005	0.995	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.005	0.995	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.005	0.995	0.000
D56 Thalassaemia	0.005	0.995	0.000
D83.8 Other common variable immunodeficiencies	0.005	0.995	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.005	0.995	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.005	0.995	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.005	0.995	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.995	0.005
D69.5 Secondary thrombocytopenia	0.005	0.995	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.005	0.995	0.000
E10.1 With ketoacidosis	0.000	0.995	0.005
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.005	0.995	0.000
D84.8 Other specified immunodeficiencies	0.005	0.995	0.000
D84.1 Defects in the complement system	0.005	0.995	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.005	0.995	0.000
E10.3 With ophthalmic complications	0.000	0.995	0.005
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.995	0.005
M35.1 Other overlap syndromes	0.000	0.995	0.005
D59 Acquired haemolytic anaemia	0.005	0.995	0.000
D58.0 Hereditary spherocytosis	0.005	0.995	0.000
E10.4 With neurological complications	0.000	0.995	0.005
M35.7 Hypermobility syndrome	0.000	0.995	0.005
H18 Other disorders of cornea	0.005	0.995	0.000
D69.9 Haemorrhagic condition, unspecified	0.005	0.995	0.000
D83.9 Common variable immunodeficiency, unspecified	0.005	0.995	0.000
E10.5 With peripheral circulatory complications	0.000	0.995	0.005
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.995	0.005
M34 Systemic sclerosis	0.000	0.995	0.005
D86.1 Sarcoidosis of lymph nodes	0.005	0.995	0.000
D67 Hereditary factor IX deficiency	0.005	0.995	0.000
E10.8 With unspecified complications	0.000	0.995	0.005
M33.1 Other dermatomyositis	0.000	0.995	0.005
H18.9 Disorder of cornea, unspecified	0.005	0.995	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.005	0.995	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.005	0.995	0.000
M33.2 Polymyositis	0.000	0.995	0.005
M80.9 Unspecified osteoporosis with pathological fracture	0.005	0.995	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.005	0.995	0.000
D58.2 Other haemoglobinopathies	0.005	0.995	0.000
D58.1 Hereditary elliptocytosis	0.005	0.995	0.000
D69.4 Other primary thrombocytopenia	0.005	0.995	0.000
H16 Keratitis	0.005	0.995	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.005	0.995	0.000
S06.2 Diffuse brain injury	0.005	0.995	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.005	0.995	0.000
D84.9 Immunodeficiency, unspecified	0.004	0.995	0.000
H18.5 Hereditary corneal dystrophies	0.005	0.995	0.000
D69.2 Other nonthrombocytopenic purpura	0.005	0.995	0.000
D69.8 Other specified haemorrhagic conditions	0.005	0.995	0.000
D69.1 Qualitative platelet defects	0.005	0.995	0.000
D66 Hereditary factor VIII deficiency	0.005	0.995	0.000
E10.2 With renal complications	0.000	0.995	0.005
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.005	0.995	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.005	0.995	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.005	0.995	0.000
R39.1 Other difficulties with micturition	0.000	0.995	0.005
G43 Migraine	0.005	0.995	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.005	0.995	0.000
H16.9 Keratitis, unspecified	0.005	0.995	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.005	0.995	0.000
M30 Polyarteritis nodosa and related conditions	0.000	0.995	0.004
E10.6 With other specified complications	0.000	0.995	0.004
H16.0 Corneal ulcer	0.005	0.995	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.995	0.004
M32.8 Other forms of systemic lupus erythematosus	0.000	0.995	0.004
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.995	0.004
M33.9 Dermatopolymyositis, unspecified	0.000	0.995	0.004
M33.0 Juvenile dermatomyositis	0.000	0.995	0.004
M79.84 Other specified soft tissue disorders (Hand)	0.004	0.996	0.000
D69.0 Allergic purpura	0.004	0.996	0.000
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
D75.2 Essential thrombocytosis	0.004	0.996	0.001
E10.7 With multiple complications	0.000	0.996	0.004
E10.0 With coma	0.000	0.996	0.004
D86.3 Sarcoidosis of skin	0.004	0.996	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.996	0.004
H21.4 Pupillary membranes	0.004	0.996	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.004	0.996	0.000
H21.2 Degeneration of iris and ciliary body	0.004	0.996	0.000
S06 Intracranial injury	0.004	0.996	0.000
H21.0 Hyphaema	0.004	0.996	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.996	0.004
Z30.1 Insertion of (intra-uterine) contraceptive device	0.004	0.996	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.996	0.004
D55.9 Anaemia due to enzyme disorder, unspecified	0.004	0.996	0.000
D55.8 Other anaemias due to enzyme disorders	0.004	0.996	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.004	0.996	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.004	0.996	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.004	0.996	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.004	0.996	0.000
D57.8 Other sickle-cell disorders	0.004	0.996	0.000
D57.3 Sickle-cell trait	0.004	0.996	0.000
D57.2 Double heterozygous sickling disorders	0.004	0.996	0.000
D57.1 Sickle-cell anaemia without crisis	0.004	0.996	0.000
D57.0 Sickle-cell anaemia with crisis	0.004	0.996	0.000
H18.8 Other specified disorders of cornea	0.004	0.996	0.000
H18.2 Other corneal oedema	0.004	0.996	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.004	0.996	0.000
M22.8 Other disorders of patella	0.000	0.996	0.004
D56.9 Thalassaemia, unspecified	0.004	0.996	0.000
D56.8 Other thalassaemias	0.004	0.996	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.004	0.996	0.000
D56.2 Delta-beta thalassaemia	0.004	0.996	0.000
D56.1 Beta thalassaemia	0.004	0.996	0.000
D56.0 Alpha thalassaemia	0.004	0.996	0.000
M79.88 Other specified soft tissue disorders (Other)	0.004	0.996	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.996	0.004
G37 Other demyelinating diseases of central nervous system	0.004	0.996	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.004	0.996	0.000
I49.4 Other and unspecified premature depolarisation	0.004	0.996	0.000
O75.8 Other specified complications of labour and delivery	0.004	0.996	0.000
M22 Disorders of patella	0.000	0.996	0.004
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.004	0.996	0.000
I22.8 Subsequent myocardial infarction of other sites	0.000	0.996	0.004
D59.8 Other acquired haemolytic anaemias	0.004	0.996	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.004	0.996	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.004	0.996	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.004	0.996	0.000
D59.3 Haemolytic-uraemic syndrome	0.004	0.996	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.004	0.996	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.004	0.996	0.000
M34.1 CR(E)ST syndrome	0.000	0.996	0.004
Y84.2 Radiological procedure and radiotherapy	0.004	0.996	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.004	0.996	0.000
H18.7 Other corneal deformities	0.004	0.996	0.000
H18.3 Changes in corneal membranes	0.004	0.996	0.000
H18.0 Corneal pigmentations and deposits	0.004	0.996	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.996	0.004
S06.3 Focal brain injury	0.004	0.996	0.000
D56.3 Thalassaemia trait	0.004	0.996	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.996	0.004
M36.3 Arthropathy in other blood disorders	0.000	0.996	0.004
M36.2 Haemophilic arthropathy	0.000	0.996	0.004
M36.1 Arthropathy in neoplastic disease	0.000	0.996	0.004
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.996	0.004
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.996	0.004
M34.0 Progressive systemic sclerosis	0.000	0.996	0.004
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.996	0.004
H21.1 Other vascular disorders of iris and ciliary body	0.004	0.996	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.996	0.004
H15 Disorders of sclera	0.004	0.996	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.004	0.996	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.004	0.996	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.004	0.996	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.004	0.996	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.004	0.996	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.004	0.996	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.003	0.996	0.000
H18.6 Keratoconus	0.004	0.996	0.000
H18.4 Corneal degeneration	0.004	0.996	0.000
R47.1 Dysarthria and anarthria	0.000	0.996	0.004
S06.0 Concussion	0.004	0.996	0.000
H16.8 Other keratitis	0.004	0.996	0.000
H16.4 Corneal neovascularisation	0.004	0.996	0.000
H16.3 Interstitial and deep keratitis	0.004	0.996	0.000
H17 Corneal scars and opacities	0.004	0.996	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.003	0.996	0.000
D59.1 Other autoimmune haemolytic anaemias	0.003	0.996	0.000
G43.0 Migraine without aura [common migraine]	0.004	0.996	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.003	0.996	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.996	0.004
G43.3 Complicated migraine	0.003	0.996	0.000
G43.2 Status migrainosus	0.003	0.996	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.003	0.996	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.003	0.996	0.000
I49.5 Sick sinus syndrome	0.004	0.996	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.996	0.003
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.996	0.003
M30.2 Juvenile polyarteritis	0.000	0.996	0.003
S06.30 Focal brain injury (without open intracranial wound)	0.003	0.996	0.000
E73.9 Lactose intolerance, unspecified	0.000	0.996	0.004
M06.9 Rheumatoid arthritis, unspecified	0.004	0.996	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.003	0.996	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.000	0.996	0.003
S02.10 Fracture of base of skull (closed)	0.004	0.996	0.000
I22 Subsequent myocardial infarction	0.000	0.996	0.004
I27.2 Other secondary pulmonary hypertension	0.004	0.996	0.000
K25.3 Acute without haemorrhage or perforation	0.003	0.997	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.997	0.003
C15.9 Oesophagus, unspecified	0.003	0.997	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.003	0.997	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.997	0.003
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.997	0.003
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.997	0.003
E89.5 Postprocedural testicular hypofunction	0.000	0.997	0.003
E89.4 Postprocedural ovarian failure	0.000	0.997	0.003
E89.1 Postprocedural hypoinsulinaemia	0.000	0.997	0.003
S06.5 Traumatic subdural haemorrhage	0.003	0.997	0.000
H16.2 Keratoconjunctivitis	0.003	0.997	0.000
S06.7 Intracranial injury with prolonged coma	0.003	0.997	0.000
S06.1 Traumatic cerebral oedema	0.003	0.997	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.003	0.997	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.003	0.997	0.000
S06.00 Concussion (without open intracranial wound)	0.003	0.997	0.000
S06.8 Other intracranial injuries	0.003	0.997	0.000
S42.10 Fracture of scapula (closed)	0.003	0.997	0.000
I49.8 Other specified cardiac arrhythmias	0.003	0.997	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.997	0.003
E83.3 Disorders of phosphorus metabolism	0.000	0.997	0.003
G43.1 Migraine with aura [classical migraine]	0.003	0.997	0.000
M30.0 Polyarteritis nodosa	0.000	0.997	0.003
N18.9 Chronic renal failure, unspecified	0.000	0.997	0.003
N28.0 Ischaemia and infarction of kidney	0.000	0.997	0.003
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.003	0.997	0.000
H18.1 Bullous keratopathy	0.003	0.997	0.000
I49 Other cardiac arrhythmias	0.003	0.997	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.997	0.003
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.997	0.003
D86.9 Sarcoidosis, unspecified	0.003	0.997	0.000
G37.5 Concentric sclerosis [Balo]	0.003	0.997	0.000
G37.4 Subacute necrotising myelitis	0.003	0.997	0.000
G37.2 Central pontine myelinolysis	0.003	0.997	0.000
G37.1 Central demyelination of corpus callosum	0.003	0.997	0.000
G37.0 Diffuse sclerosis	0.003	0.997	0.000
M22.1 Recurrent subluxation of patella	0.000	0.997	0.003
M22.9 Disorder of patella, unspecified	0.000	0.997	0.003
H15.1 Episcleritis	0.003	0.997	0.000
G36 Other acute disseminated demyelination	0.003	0.997	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.997	0.003
I12 Hypertensive renal disease	0.000	0.997	0.003
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
E73 Lactose intolerance	0.000	0.997	0.003
D75.1 Secondary polycythaemia	0.001	0.997	0.002
S06.4 Epidural haemorrhage	0.003	0.997	0.000
H60-H62 Diseases of external ear	0.003	0.997	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.997	0.003
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
H17.8 Other corneal scars and opacities	0.003	0.997	0.000
K25.7 Chronic without haemorrhage or perforation	0.003	0.997	0.000
H15.9 Disorder of sclera, unspecified	0.003	0.997	0.000
H15.8 Other disorders of sclera	0.003	0.997	0.000
H15.0 Scleritis	0.003	0.997	0.000
Z85.4 Personal history of malignant neoplasm of genital organs	0.003	0.997	0.000
S06.01 Concussion (with open intracranial wound)	0.003	0.997	0.000
I49.9 Cardiac arrhythmia, unspecified	0.003	0.997	0.000
H17.1 Other central corneal opacity	0.003	0.997	0.000
H17.0 Adherent leukoma	0.003	0.997	0.000
H17.9 Corneal scar and opacity, unspecified	0.003	0.997	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.003	0.997	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.003	0.997	0.000
S06.9 Intracranial injury, unspecified	0.003	0.997	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.003	0.997	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.003	0.997	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.997	0.003
U80.1 Methicillin resistant agent	0.000	0.997	0.003
E89.2 Postprocedural hypoparathyroidism	0.000	0.997	0.003
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.003	0.997	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
M22.0 Recurrent dislocation of patella	0.000	0.997	0.003
O16 Unspecified maternal hypertension	0.003	0.997	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.997	0.003
O46 Antepartum haemorrhage, not elsewhere classified	0.003	0.997	0.000
N18.3 Chronic kidney disease, stage 3	0.000	0.997	0.003
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.997	0.003
H22.1 Iridocyclitis in other diseases classified elsewhere	0.003	0.997	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations