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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs238876
log Bayes Factor = 44.7528
Chromosome 6   position 29,349,609  (GRCh37) Explore rs238876 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.9 Without complications
0.000 0.003 0.997
E16.2 Hypoglycaemia, unspecified
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.003 0.997
E16 Other disorders of pancreatic internal secretion
0.000 0.004 0.996
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.004 0.996
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.004 0.996
E00-E07 Disorders of thyroid gland
0.000 0.006 0.994
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.009 0.991
E10.3 With ophthalmic complications
0.000 0.047 0.953
E10.2 With renal complications
0.000 0.075 0.925
E10.4 With neurological complications
0.000 0.081 0.919
E16.1 Other hypoglycaemia
0.000 0.155 0.845
E13 Other specified diabetes mellitus
0.000 0.176 0.824
E10.1 With ketoacidosis
0.000 0.197 0.803
E14 Unspecified diabetes mellitus
0.000 0.201 0.799
E05.8 Other thyrotoxicosis
0.000 0.209 0.791
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.244 0.756
E10.6 With other specified complications
0.000 0.252 0.748
E10.0 With coma
0.000 0.259 0.741
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.714
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.714
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.714
E16.3 Increased secretion of glucagon
0.000 0.285 0.714
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
E13.9 Without complications
0.000 0.286 0.714
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.287 0.713
E00 Congenital iodine-deficiency syndrome
0.000 0.287 0.713
E10.7 With multiple complications
0.000 0.293 0.707
E14.3 With ophthalmic complications
0.000 0.293 0.707
E40-E46 Malnutrition
0.000 0.351 0.649
E10.5 With peripheral circulatory complications
0.000 0.361 0.638
E14.6 With other specified complications
0.000 0.366 0.634
E14.8 With unspecified complications
0.000 0.373 0.627
E14.1 With ketoacidosis
0.000 0.390 0.609
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.597 0.403 0.000
E14.4 With neurological complications
0.000 0.405 0.595
E13.8 With unspecified complications
0.000 0.409 0.591
E13.7 With multiple complications
0.000 0.409 0.591
E13.6 With other specified complications
0.000 0.409 0.591
E13.5 With peripheral circulatory complications
0.000 0.409 0.591
E13.4 With neurological complications
0.000 0.409 0.591
E13.2 With renal complications
0.000 0.409 0.591
E13.1 With ketoacidosis
0.000 0.409 0.591
E13.0 With coma
0.000 0.409 0.591
E06 Thyroiditis
0.000 0.413 0.587
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.418 0.581
E14.7 With multiple complications
0.000 0.427 0.572
E14.0 With coma
0.000 0.427 0.572
E07 Other disorders of thyroid
0.000 0.430 0.570
E14.2 Withrenal complications
0.000 0.436 0.564
E13.3 With ophthalmic complications
0.000 0.437 0.563
E10.8 With unspecified complications
0.000 0.467 0.533
E14.5 With peripheral circulatory complications
0.000 0.472 0.528
E12.9 Without complications
0.000 0.487 0.512
E12.8 With unspecified complications
0.000 0.487 0.512
E12.7 With multiple complications
0.000 0.487 0.512
E12.6 With other specified complications
0.000 0.487 0.512
E12.5 With peripheral circulatory complications
0.000 0.487 0.512
E12.4 With neurological complications
0.000 0.487 0.512
E12.3 With ophthalmic complications
0.000 0.487 0.512
E12.2 With renal complications
0.000 0.487 0.512
E12.1 With ketoacidosis
0.000 0.487 0.512
E12.0 With coma
0.000 0.487 0.512
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.489 0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.489 0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.489 0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.489 0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.489 0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.489 0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.489 0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.489 0.511
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.534 0.466
E45 Retarded development following protein-energy malnutrition
0.000 0.534 0.466
E43 Unspecified severe protein-energy malnutrition
0.000 0.534 0.466
E42 Marasmic kwashiorkor
0.000 0.534 0.466
E41 Nutritional marasmus
0.000 0.534 0.466
E40 Kwashiorkor
0.000 0.534 0.466
E06.9 Thyroiditis, unspecified
0.000 0.541 0.459
E06.1 Subacute thyroiditis
0.000 0.549 0.451
E07.8 Other specified disorders of thyroid
0.000 0.563 0.437
E03 Other hypothyroidism
0.000 0.565 0.435
E06.5 Other chronic thyroiditis
0.000 0.570 0.430
E06.4 Drug-induced thyroiditis
0.000 0.579 0.421
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.579 0.421
E06.0 Acute thyroiditis
0.000 0.579 0.421
E07.1 Dyshormogenetic goitre
0.000 0.591 0.409
E07.0 Hypersecretion of calcitonin
0.000 0.591 0.409
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.595 0.404
E46 Unspecified protein-energy malnutrition
0.000 0.599 0.401
K90 Intestinal malabsorption
0.000 0.602 0.398
E50-E64 Other nutritional deficiencies
0.000 0.628 0.372
E65-E68 Obesity and other hyperalimentation
0.000 0.652 0.348
E44.1 Mild protein-energy malnutrition
0.000 0.666 0.334
E44.0 Moderate protein-energy malnutrition
0.000 0.666 0.334
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.678 0.322
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.679 0.321
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.684 0.316
E03.5 Myxoedema coma
0.000 0.688 0.312
E03.4 Atrophy of thyroid (acquired)
0.000 0.688 0.312
E03.3 Postinfectious hypothyroidism
0.000 0.688 0.312
E03.1 Congenital hypothyroidism without goitre
0.000 0.690 0.309
K90.3 Pancreatic steatorrhoea
0.000 0.714 0.285
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.714 0.285
K90.1 Tropical sprue
0.000 0.714 0.285
E03.8 Other specified hypothyroidism
0.000 0.716 0.284
E51 Thiamine deficiency
0.000 0.724 0.276
K90.9 Intestinal malabsorption, unspecified
0.000 0.726 0.274
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.733 0.267
E50 Vitamin A deficiency
0.000 0.733 0.267
E60 Dietary zinc deficiency
0.000 0.733 0.267
E59 Dietary selenium deficiency
0.000 0.733 0.267
E54 Ascorbic acid deficiency
0.000 0.733 0.267
E52 Niacin deficiency [pellagra]
0.000 0.733 0.267
E56 Other vitamin deficiencies
0.000 0.744 0.255
E67 Other hyperalimentation
0.000 0.750 0.249
E68 Sequelae of hyperalimentation
0.000 0.750 0.249
E58 Dietary calcium deficiency
0.000 0.752 0.248
E83 Disorders of mineral metabolism
0.243 0.756 0.000
E63 Other nutritional deficiencies
0.000 0.761 0.239
K90.8 Other intestinal malabsorption
0.000 0.763 0.237
E55 Vitamin D deficiency
0.000 0.767 0.233
E61 Deficiency of other nutrient elements
0.000 0.774 0.226
E53 Deficiency of other B group vitamins
0.000 0.791 0.209
E83.3 Disorders of phosphorus metabolism
0.208 0.791 0.000
E65 Localised adiposity
0.000 0.792 0.208
E51.2 Wernicke's encephalopathy
0.000 0.793 0.207
E07.9 Disorder of thyroid, unspecified
0.000 0.800 0.200
E51.9 Thiamine deficiency, unspecified
0.000 0.802 0.198
E51.8 Other manifestations of thiamine deficiency
0.000 0.802 0.198
E51.1 Beriberi
0.000 0.802 0.198
E50.9 Vitamin A deficiency, unspecified
0.000 0.808 0.191
E50.8 Other manifestations of vitamin A deficiency
0.000 0.808 0.191
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.808 0.191
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.808 0.191
E50.5 Vitamin A deficiency with night blindness
0.000 0.808 0.191
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.808 0.191
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.808 0.191
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.808 0.191
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.808 0.191
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.808 0.191
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.808 0.191
E64.8 Sequelae of other nutritional deficiencies
0.000 0.808 0.191
E64.3 Sequelae of rickets
0.000 0.808 0.191
E64.2 Sequelae of vitamin C deficiency
0.000 0.808 0.191
E64.1 Sequelae of vitamin A deficiency
0.000 0.808 0.191
E64.0 Sequelae of protein-energy malnutrition
0.000 0.808 0.191
E83.9 Disorder of mineral metabolism, unspecified
0.190 0.810 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.816 0.183
E56.8 Deficiency of other vitamins
0.000 0.816 0.183
E56.0 Deficiency of vitamin E
0.000 0.816 0.183
E11 Non-insulin-dependent diabetes mellitus
0.000 0.819 0.181
E67.8 Other specified hyperalimentation
0.000 0.821 0.179
E67.3 Hypervitaminosis D
0.000 0.821 0.179
E67.2 Megavitamin-B6 syndrome
0.000 0.821 0.179
E67.1 Hypercarotenaemia
0.000 0.821 0.179
E67.0 Hypervitaminosis A
0.000 0.821 0.179
E83.8 Other disorders of mineral metabolism
0.175 0.825 0.000
E83.2 Disorders of zinc metabolism
0.175 0.825 0.000
E83.0 Disorders of copper metabolism
0.175 0.825 0.000
E56.1 Deficiency of vitamin K
0.000 0.828 0.172
E63.8 Other specified nutritional deficiencies
0.000 0.828 0.172
E63.1 Imbalance of constituents of food intake
0.000 0.828 0.172
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.828 0.172
E11.6 With other specified complications
0.000 0.828 0.172
E55.0 Rickets, active
0.000 0.833 0.167
E53.9 Vitamin B deficiency, unspecified
0.000 0.835 0.165
E61.9 Deficiency of nutrient element, unspecified
0.000 0.838 0.162
E61.8 Deficiency of other specified nutrient elements
0.000 0.838 0.162
E61.7 Deficiency of multiple nutrient elements
0.000 0.838 0.162
E61.6 Vanadium deficiency
0.000 0.838 0.162
E61.5 Molybdenum deficiency
0.000 0.838 0.162
E61.4 Chromium deficiency
0.000 0.838 0.162
E61.3 Manganese deficiency
0.000 0.838 0.162
E61.0 Copper deficiency
0.000 0.838 0.162
E61.1 Iron deficiency
0.000 0.843 0.157
E53.1 Pyridoxine deficiency
0.000 0.850 0.150
E53.0 Riboflavin deficiency
0.000 0.850 0.150
E63.9 Nutritional deficiency, unspecified
0.000 0.856 0.144
E55.9 Vitamin D deficiency, unspecified
0.000 0.866 0.134
E11.1 With ketoacidosis
0.000 0.867 0.133
E11.7 With multiple complications
0.000 0.870 0.130
E61.2 Magnesium deficiency
0.000 0.870 0.130
E83.4 Disorders of magnesium metabolism
0.126 0.874 0.000
E14.9 Without complications
0.000 0.880 0.120
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.880 0.120
E11.8 With unspecified complications
0.000 0.882 0.118
E11.2 With renal complications
0.000 0.885 0.115
E11.0 With coma
0.000 0.890 0.110
I83 Varicose veins of lower extremities
0.106 0.894 0.000
E11.3 With ophthalmic complications
0.000 0.900 0.100
E06.3 Autoimmune thyroiditis
0.002 0.902 0.097
C20 Malignant neoplasm of rectum
0.000 0.912 0.088
E20-E35 Disorders of other endocrine glands
0.000 0.914 0.086
C15-C26 Malignant neoplasms of digestive organs
0.000 0.919 0.081
C15 Malignant neoplasm of oesophagus
0.000 0.923 0.077
I83.0 Varicose veins of lower extremities with ulcer
0.074 0.926 0.000
C15.4 Middle third of oesophagus
0.000 0.928 0.072
E11.5 With peripheral circulatory complications
0.000 0.928 0.072
E24 Cushing's syndrome
0.000 0.929 0.071
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.071 0.929 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.929 0.070
C15.5 Lower third of oesophagus
0.000 0.932 0.068
E21.3 Hyperparathyroidism, unspecified
0.000 0.935 0.065
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.937 0.063
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.938 0.062
E32 Diseases of thymus
0.000 0.938 0.062
E30 Disorders of puberty, not elsewhere classified
0.000 0.938 0.062
C25 Malignant neoplasm of pancreas
0.000 0.938 0.062
C17 Malignant neoplasm of small intestine
0.000 0.939 0.061
E20 Hypoparathyroidism
0.000 0.939 0.060
E25 Adrenogenital disorders
0.000 0.941 0.059
E31 Polyglandular dysfunction
0.000 0.941 0.059
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.942 0.058
E24.2 Drug-induced Cushing's syndrome
0.000 0.942 0.058
E22 Hyperfunction of pituitary gland
0.000 0.943 0.057
E03.9 Hypothyroidism, unspecified
0.000 0.943 0.057
C24.0 Extrahepatic bile duct
0.000 0.943 0.057
E24.0 Pituitary-dependent Cushing's disease
0.000 0.943 0.056
C17.0 Duodenum
0.000 0.944 0.056
C15.1 Thoracic part of oesophagus
0.000 0.944 0.055
C15.8 Overlapping lesion of oesophagus
0.000 0.945 0.055
C15.2 Abdominal part of oesophagus
0.000 0.945 0.055
E21.2 Other hyperparathyroidism
0.000 0.946 0.054
E53.8 Deficiency of other specified B group vitamins
0.000 0.946 0.054
C15.0 Cervical part of oesophagus
0.000 0.948 0.052
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.949 0.051
E24.3 Ectopic ACTH syndrome
0.000 0.949 0.051
E24.1 Nelson's syndrome
0.000 0.949 0.051
E29 Testicular dysfunction
0.000 0.949 0.051
E24.8 Other Cushing's syndrome
0.000 0.949 0.051
C15.3 Upper third of oesophagus
0.000 0.949 0.051
E21.4 Other specified disorders of parathyroid gland
0.000 0.949 0.051
C25.3 Pancreatic duct
0.000 0.949 0.051
E24.9 Cushing's syndrome, unspecified
0.000 0.950 0.050
C25.1 Body of pancreas
0.000 0.950 0.050
C25.8 Overlapping lesion of pancreas
0.000 0.950 0.050
C15.9 Oesophagus, unspecified
0.000 0.951 0.049
E28 Ovarian dysfunction
0.000 0.953 0.047
C24.9 Biliary tract, unspecified
0.000 0.953 0.047
C25.2 Tail of pancreas
0.000 0.953 0.047
E26 Hyperaldosteronism
0.000 0.954 0.046
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.954 0.046
E04 Other non-toxic goitre
0.003 0.954 0.043
C24.8 Overlapping lesion of biliary tract
0.000 0.955 0.045
C17.1 Jejunum
0.000 0.955 0.045
E30.9 Disorder of puberty, unspecified
0.000 0.955 0.045
E30.8 Other disorders of puberty
0.000 0.955 0.045
E30.1 Precocious puberty
0.000 0.955 0.045
E30.0 Delayed puberty
0.000 0.955 0.045
E32.9 Disease of thymus, unspecified
0.000 0.955 0.045
E32.8 Other diseases of thymus
0.000 0.955 0.045
E32.1 Abscess of thymus
0.000 0.955 0.045
E32.0 Persistent hyperplasia of thymus
0.000 0.955 0.045
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.955 0.045
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.955 0.045
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.955 0.045
C25.4 Endocrine pancreas
0.000 0.955 0.045
E22.1 Hyperprolactinaemia
0.000 0.955 0.045
C17.8 Overlapping lesion of small intestine
0.000 0.956 0.044
C17.3 Meckel's diverticulum
0.000 0.956 0.044
E20.8 Other hypoparathyroidism
0.000 0.956 0.043
E20.1 Pseudohypoparathyroidism
0.000 0.956 0.043
E20.0 Idiopathic hypoparathyroidism
0.000 0.956 0.043
E25.9 Adrenogenital disorder, unspecified
0.000 0.957 0.043
E25.8 Other adrenogenital disorders
0.000 0.957 0.043
E31.9 Polyglandular dysfunction, unspecified
0.000 0.958 0.042
E31.8 Other polyglandular dysfunction
0.000 0.958 0.042
E31.1 Polyglandular hyperfunction
0.000 0.958 0.042
E34 Other endocrine disorders
0.000 0.958 0.042
E20.9 Hypoparathyroidism, unspecified
0.000 0.958 0.042
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.959 0.041
E22.8 Other hyperfunction of pituitary gland
0.000 0.959 0.041
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.959 0.041
E11.4 With neurological complications
0.000 0.959 0.041
C25.9 Pancreas, unspecified
0.000 0.960 0.040
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.960 0.040
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.960 0.040
E31.0 Autoimmune polyglandular failure
0.000 0.961 0.039
C25.7 Other parts of pancreas
0.000 0.962 0.038
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.962 0.038
E29.9 Testicular dysfunction, unspecified
0.000 0.963 0.037
E29.8 Other testicular dysfunction
0.000 0.963 0.037
E29.0 Testicular hyperfunction
0.000 0.963 0.037
C22.9 Liver, unspecified
0.000 0.964 0.036
C25.0 Head of pancreas
0.000 0.964 0.036
C17.9 Small intestine, unspecified
0.000 0.966 0.034
E11.9 Without complications
0.000 0.966 0.034
E28.9 Ovarian dysfunction, unspecified
0.000 0.966 0.034
E28.8 Other ovarian dysfunction
0.000 0.966 0.034
E28.1 Androgen excess
0.000 0.966 0.034
E28.0 Oestrogen excess
0.000 0.966 0.034
E22.0 Acromegaly and pituitary gigantism
0.000 0.966 0.034
E26.8 Other hyperaldosteronism
0.000 0.966 0.033
E26.1 Secondary hyperaldosteronism
0.000 0.966 0.033
C22.7 Other specified carcinomas of liver
0.000 0.967 0.033
C22.4 Other sarcomas of liver
0.000 0.967 0.033
C22.3 Angiosarcoma of liver
0.000 0.967 0.033
C22.2 Hepatoblastoma
0.000 0.967 0.033
E04.8 Other specified non-toxic goitre
0.002 0.967 0.031
E26.9 Hyperaldosteronism, unspecified
0.000 0.968 0.031
C23 Malignant neoplasm of gallbladder
0.000 0.968 0.031
C22.1 Intrahepatic bile duct carcinoma
0.000 0.969 0.031
E34.3 Short stature, not elsewhere classified
0.000 0.969 0.030
E34.5 Androgen resistance syndrome
0.000 0.969 0.030
E34.4 Constitutional tall stature
0.000 0.969 0.030
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.969 0.030
E34.1 Other hypersecretion of intestinal hormones
0.000 0.969 0.030
C26.8 Overlapping lesion of digestive system
0.000 0.970 0.029
C26.1 Spleen
0.000 0.970 0.029
E34.9 Endocrine disorder, unspecified
0.000 0.970 0.030
C18.9 Colon, unspecified
0.000 0.971 0.029
E28.2 Polycystic ovarian syndrome
0.000 0.971 0.029
E23 Hypofunction and other disorders of pituitary gland
0.000 0.971 0.028
C17.2 Ileum
0.000 0.972 0.028
C18 Malignant neoplasm of colon
0.000 0.972 0.028
E27 Other disorders of adrenal gland
0.000 0.973 0.027
E21.0 Primary hyperparathyroidism
0.000 0.973 0.027
C21 Malignant neoplasm of anus and anal canal
0.000 0.973 0.027
E28.3 Primary ovarian failure
0.000 0.973 0.027
I83.1 Varicose veins of lower extremities with inflammation
0.026 0.974 0.000
E29.1 Testicular hypofunction
0.000 0.974 0.026
C18.1 Appendix
0.000 0.975 0.025
E34.8 Other specified endocrine disorders
0.000 0.975 0.024
C24.1 Ampulla of Vater
0.001 0.976 0.023
C26.0 Intestinal tract, part unspecified
0.000 0.977 0.023
K90-K93 Other diseases of the digestive system
0.000 0.977 0.023
E27.1 Primary adrenocortical insufficiency
0.000 0.977 0.023
C26.9 Ill-defined sites within the digestive system
0.000 0.978 0.022
E04.0 Non-toxic diffuse goitre
0.002 0.978 0.020
E34.0 Carcinoid syndrome
0.000 0.978 0.022
C18.8 Overlapping lesion of colon
0.000 0.978 0.022
E26.0 Primary hyperaldosteronism
0.000 0.979 0.021
E66 Obesity
0.000 0.979 0.021
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.979 0.021
E23.1 Drug-induced hypopituitarism
0.000 0.979 0.021
E23.7 Disorder of pituitary gland, unspecified
0.000 0.980 0.020
E27.5 Adrenomedullary hyperfunction
0.000 0.980 0.020
E27.0 Other adrenocortical overactivity
0.000 0.980 0.020
C21.2 Cloacogenic zone
0.000 0.980 0.019
E27.9 Disorder of adrenal gland, unspecified
0.000 0.982 0.018
C18.2 Ascending colon
0.000 0.982 0.017
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.983 0.017
C22.0 Liver cell carcinoma
0.000 0.983 0.017
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.983 0.017
E23.6 Other disorders of pituitary gland
0.000 0.983 0.017
E23.2 Diabetes insipidus
0.000 0.984 0.016
O04.9 Complete or unspecified, without complication
0.016 0.984 0.000
Z71.8 Other specified counselling
0.016 0.984 0.000
E27.2 Addisonian crisis
0.000 0.984 0.015
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.984 0.015
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.984 0.015
E66.1 Drug-induced obesity
0.000 0.984 0.015
C18.6 Descending colon
0.000 0.986 0.014
O04 Medical abortion
0.014 0.986 0.000
C16 Malignant neoplasm of stomach
0.000 0.987 0.013
C21.0 Anus, unspecified
0.000 0.987 0.013
C18.4 Transverse colon
0.000 0.987 0.013
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.988 0.012
K93.1 Megacolon in Chagas' disease
0.000 0.988 0.012
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.988 0.012
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.012 0.988 0.000
E83.5 Disorders of calcium metabolism
0.012 0.988 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.988 0.011
C21.1 Anal canal
0.000 0.988 0.011
C18.7 Sigmoid colon
0.000 0.989 0.011
E04.9 Non-toxic goitre, unspecified
0.001 0.989 0.010
E23.0 Hypopituitarism
0.000 0.989 0.011
E66.0 Obesity due to excess calories
0.000 0.989 0.011
C18.3 Hepatic flexure
0.000 0.989 0.011
O04.8 Complete or unspecified, with other and unspecified complications
0.010 0.990 0.000
H40.2 Primary angle-closure glaucoma
0.010 0.990 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.990 0.010
O04.7 Complete or unspecified, complicated by embolism
0.010 0.990 0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.010 0.990 0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.010 0.990 0.000
O04.3 Incomplete, with other and unspecified complications
0.010 0.990 0.000
O04.2 Incomplete, complicated by embolism
0.010 0.990 0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection
0.010 0.990 0.000
C16.5 Lesser curvature of stomach, unspecified
0.000 0.990 0.010
O04.4 Incomplete, without complication
0.010 0.990 0.000
C16.8 Overlapping lesion of stomach
0.000 0.991 0.009
C18.5 Splenic flexure
0.000 0.991 0.009
C16.1 Fundus of stomach
0.000 0.991 0.008
O03 Spontaneous abortion
0.009 0.991 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.009 0.991 0.000
E70-E90 Metabolic disorders
0.004 0.991 0.004
C16.2 Body of stomach
0.000 0.991 0.008
C16.4 Pylorus
0.000 0.992 0.008
O00-O08 Pregnancy with abortive outcome
0.008 0.992 0.000
C16.9 Stomach, unspecified
0.000 0.992 0.008
C16.6 Greater curvature of stomach, unspecified
0.000 0.992 0.008
K14.8 Other diseases of tongue
0.000 0.992 0.008
C16.0 Cardia
0.000 0.992 0.008
O03.4 Incomplete, without complication
0.008 0.992 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.008 0.992 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.007 0.992 0.000
H40.5 Glaucoma secondary to other eye disorders
0.007 0.993 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.007 0.993 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.000 0.993 0.007
C18.0 Caecum
0.000 0.993 0.007
C16.3 Pyloric antrum
0.000 0.993 0.006
T92 Sequelae of injuries of upper limb
0.000 0.993 0.007
O03.7 Complete or unspecified, complicated by embolism
0.006 0.994 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.006 0.994 0.000
O03.2 Incomplete, complicated by embolism
0.006 0.994 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.006 0.994 0.000
O06 Unspecified abortion
0.006 0.994 0.000
E77 Disorders of glycoprotein metabolism
0.003 0.994 0.003
E76 Disorders of glycosaminoglycan metabolism
0.003 0.994 0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.003 0.994 0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.003 0.994 0.003
T92.0 Sequelae of open wound of upper limb
0.000 0.994 0.006
E70 Disorders of aromatic amino-acid metabolism
0.003 0.994 0.003
E79 Disorders of purine and pyrimidine metabolism
0.003 0.994 0.003
E72 Other disorders of amino-acid metabolism
0.003 0.994 0.003
O03.3 Incomplete, with other and unspecified complications
0.006 0.994 0.000
E84 Cystic fibrosis
0.003 0.994 0.003
O07 Failed attempted abortion
0.006 0.994 0.000
O05 Other abortion
0.006 0.994 0.000
O01 Hydatidiform mole
0.006 0.994 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.003 0.994 0.003
E04.1 Non-toxic single thyroid nodule
0.003 0.994 0.004
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.994 0.006
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)
0.000 0.994 0.006
E74 Other disorders of carbohydrate metabolism
0.003 0.994 0.003
E73 Lactose intolerance
0.002 0.994 0.004
T92.1 Sequelae of fracture of arm
0.000 0.994 0.006
O02 Other abnormal products of conception
0.006 0.994 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.006 0.994 0.000
E85 Amyloidosis
0.003 0.994 0.003
O08 Complications following abortion and ectopic and molar pregnancy
0.005 0.994 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.000 0.994 0.006
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.000 0.995 0.005
H66.3 Other chronic suppurative otitis media
0.005 0.995 0.000
H40 Glaucoma
0.005 0.995 0.000
J69.0 Pneumonitis due to food and vomit
0.000 0.995 0.005
O06.9 Complete or unspecified, without complication
0.005 0.995 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.005 0.995 0.000
O06.8 Complete or unspecified, with other and unspecified complications
0.005 0.995 0.000
O06.7 Complete or unspecified, complicated by embolism
0.005 0.995 0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.005 0.995 0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.005 0.995 0.000
O06.4 Incomplete, without complication
0.005 0.995 0.000
O06.3 Incomplete, with other and unspecified complications
0.005 0.995 0.000
O06.2 Incomplete, complicated by embolism
0.005 0.995 0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage
0.005 0.995 0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection
0.005 0.995 0.000
E71.3 Disorders of fatty-acid metabolism
0.002 0.995 0.003
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.002 0.995 0.003
E71.1 Other disorders of branched-chain amino-acid metabolism
0.002 0.995 0.003
E71.0 Maple-syrup-urine disease
0.002 0.995 0.003
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.002 0.995 0.003
E76.8 Other disorders of glucosaminoglycan metabolism
0.002 0.995 0.003
E76.3 Mucopolysaccharidosis, unspecified
0.002 0.995 0.003
E76.2 Other mucopolysaccharidoses
0.002 0.995 0.003
E76.1 Mucopolysaccharidosis, type II
0.002 0.995 0.003
E76.0 Mucopolysaccharidosis, type I
0.002 0.995 0.003
E77.9 Disorder of glycoprotein metabolism, unspecified
0.002 0.995 0.003
E77.8 Other disorders of glycoprotein metabolism
0.002 0.995 0.003
E77.1 Defects in glycoprotein degradation
0.002 0.995 0.003
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.002 0.995 0.003
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.002 0.995 0.002
E70.8 Other disorders of aromatic amino-acid metabolism
0.002 0.995 0.002
E70.2 Disorders of tyrosine metabolism
0.002 0.995 0.002
E70.1 Other hyperphenylalaninaemias
0.002 0.995 0.002
E70.0 Classical phenylketonuria
0.002 0.995 0.002
E72.9 Disorder of amino-acid metabolism, unspecified
0.003 0.995 0.002
E72.8 Other specified disorders of amino-acid metabolism
0.003 0.995 0.002
E72.5 Disorders of glycine metabolism
0.003 0.995 0.002
E72.4 Disorders of ornithine metabolism
0.003 0.995 0.002
E72.3 Disorders of lysine and hydroxylysine metabolism
0.003 0.995 0.002
E72.2 Disorders of urea cycle metabolism
0.003 0.995 0.002
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.003 0.995 0.002
E79.8 Other disorders of purine and pyrimidine metabolism
0.003 0.995 0.002
E79.1 Lesch-Nyhan syndrome
0.003 0.995 0.002
E88 Other metabolic disorders
0.002 0.995 0.003
E84.8 Cystic fibrosis with other manifestations
0.003 0.995 0.002
E84.1 Cystic fibrosis with intestinal manifestations
0.003 0.995 0.002
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.000 0.995 0.005
E04.2 Non-toxic multinodular goitre
0.003 0.995 0.002
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.003 0.995 0.002
E75.6 Lipid storage disorder, unspecified
0.002 0.995 0.002
E75.4 Neuronal ceroid lipofuscinosis
0.002 0.995 0.002
E75.3 Sphingolipidosis, unspecified
0.002 0.995 0.002
E75.1 Other gangliosidosis
0.002 0.995 0.002
E75.0 GM2 gangliosidosis
0.002 0.995 0.002
O01.9 Hydatidiform mole, unspecified
0.005 0.995 0.000
O01.1 Incomplete and partial hydatidiform mole
0.005 0.995 0.000
O01.0 Classical hydatidiform mole
0.005 0.995 0.000
O05.9 Complete or unspecified, without complication
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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