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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2393911
log Bayes Factor = 57.9165
Chromosome 6   position 27,057,079  (GRCh37) Explore rs2393911 on Ensembl!
Variant rs2393911 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
N40 Hyperplasia of prostate
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.997 0.003 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.997 0.003 0.000
E05.9 Thyrotoxicosis, unspecified
0.997 0.003 0.000
E03 Other hypothyroidism
0.997 0.003 0.000
E03.9 Hypothyroidism, unspecified
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.984 0.016 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.977 0.023 0.000
E16 Other disorders of pancreatic internal secretion
0.973 0.027 0.000
E16.2 Hypoglycaemia, unspecified
0.968 0.032 0.000
K90 Intestinal malabsorption
0.958 0.042 0.000
E10-E14 Diabetes mellitus
0.937 0.063 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.917 0.083 0.000
K90.9 Intestinal malabsorption, unspecified
0.912 0.088 0.000
E10 Insulin-dependent diabetes mellitus
0.909 0.091 0.000
R31 Unspecified haematuria
0.000 0.091 0.909
E20-E35 Disorders of other endocrine glands
0.898 0.102 0.000
E10.9 Without complications
0.898 0.102 0.000
E27 Other disorders of adrenal gland
0.879 0.121 0.000
E27.1 Primary adrenocortical insufficiency
0.851 0.149 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.845 0.155 0.000
E14 Unspecified diabetes mellitus
0.797 0.203 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.771 0.229 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.761 0.238 0.000
E13 Other specified diabetes mellitus
0.750 0.250 0.000
E03.8 Other specified hypothyroidism
0.748 0.251 0.000
E50-E64 Other nutritional deficiencies
0.746 0.254 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.745 0.255 0.000
E31 Polyglandular dysfunction
0.719 0.281 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.715 0.285 0.000
E00 Congenital iodine-deficiency syndrome
0.715 0.285 0.000
E05.5 Thyroid crisis or storm
0.715 0.285 0.000
E05.4 Thyrotoxicosis factitia
0.715 0.285 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.715 0.285 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.715 0.285 0.000
E03.5 Myxoedema coma
0.715 0.285 0.000
E03.4 Atrophy of thyroid (acquired)
0.715 0.285 0.000
E03.3 Postinfectious hypothyroidism
0.715 0.285 0.000
E03.1 Congenital hypothyroidism without goitre
0.715 0.285 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.715 0.285 0.000
E16.1 Other hypoglycaemia
0.714 0.286 0.000
E10.7 With multiple complications
0.711 0.289 0.000
E10.2 With renal complications
0.703 0.297 0.000
E15 Nondiabetic hypoglycaemic coma
0.701 0.299 0.000
E27.2 Addisonian crisis
0.698 0.302 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.697 0.303 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.697 0.303 0.000
E16.4 Abnormal secretion of gastrin
0.697 0.303 0.000
E16.3 Increased secretion of glucagon
0.697 0.303 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.696 0.304 0.000
E40-E46 Malnutrition
0.691 0.309 0.000
E10.1 With ketoacidosis
0.691 0.309 0.000
K90.3 Pancreatic steatorrhoea
0.687 0.313 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.687 0.313 0.000
K90.1 Tropical sprue
0.687 0.313 0.000
E14.5 With peripheral circulatory complications
0.686 0.314 0.000
E12 Malnutrition-related diabetes mellitus
0.671 0.328 0.000
E25 Adrenogenital disorders
0.669 0.330 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.663 0.336 0.000
E10.3 With ophthalmic complications
0.661 0.339 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.649 0.351 0.000
E10.5 With peripheral circulatory complications
0.649 0.351 0.000
E24 Cushing's syndrome
0.645 0.355 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.644 0.356 0.000
E32 Diseases of thymus
0.644 0.356 0.000
E30 Disorders of puberty, not elsewhere classified
0.644 0.356 0.000
E10.8 With unspecified complications
0.642 0.358 0.000
E14.3 With ophthalmic complications
0.637 0.363 0.000
E55 Vitamin D deficiency
0.634 0.366 0.000
E20 Hypoparathyroidism
0.633 0.367 0.000
E27.5 Adrenomedullary hyperfunction
0.631 0.369 0.000
E27.0 Other adrenocortical overactivity
0.631 0.369 0.000
E14.1 With ketoacidosis
0.621 0.379 0.000
E23 Hypofunction and other disorders of pituitary gland
0.615 0.385 0.000
E22 Hyperfunction of pituitary gland
0.608 0.392 0.000
E07 Other disorders of thyroid
0.605 0.394 0.000
K90.8 Other intestinal malabsorption
0.605 0.394 0.000
E13.9 Without complications
0.602 0.398 0.000
E05.8 Other thyrotoxicosis
0.601 0.399 0.000
E10.0 With coma
0.601 0.399 0.000
E14.6 With other specified complications
0.600 0.400 0.000
E14.2 Withrenal complications
0.592 0.408 0.000
E34 Other endocrine disorders
0.591 0.409 0.000
E31.0 Autoimmune polyglandular failure
0.591 0.409 0.000
E14.7 With multiple complications
0.572 0.428 0.000
E14.0 With coma
0.572 0.428 0.000
E06 Thyroiditis
0.565 0.435 0.000
E24.2 Drug-induced Cushing's syndrome
0.560 0.440 0.000
E13.3 With ophthalmic complications
0.559 0.441 0.000
E10.6 With other specified complications
0.558 0.442 0.000
E55.9 Vitamin D deficiency, unspecified
0.554 0.446 0.000
E27.9 Disorder of adrenal gland, unspecified
0.548 0.452 0.000
E61 Deficiency of other nutrient elements
0.547 0.453 0.000
E26 Hyperaldosteronism
0.545 0.455 0.000
E56 Other vitamin deficiencies
0.540 0.459 0.000
E13.8 With unspecified complications
0.538 0.462 0.000
E13.7 With multiple complications
0.538 0.462 0.000
E13.6 With other specified complications
0.538 0.462 0.000
E13.5 With peripheral circulatory complications
0.538 0.462 0.000
E13.4 With neurological complications
0.538 0.462 0.000
E13.2 With renal complications
0.538 0.462 0.000
E13.1 With ketoacidosis
0.538 0.462 0.000
E13.0 With coma
0.538 0.462 0.000
E21.0 Primary hyperparathyroidism
0.537 0.463 0.000
E28 Ovarian dysfunction
0.535 0.465 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.535 0.465 0.000
E63 Other nutritional deficiencies
0.535 0.465 0.000
E50 Vitamin A deficiency
0.535 0.465 0.000
E60 Dietary zinc deficiency
0.535 0.465 0.000
E59 Dietary selenium deficiency
0.535 0.465 0.000
E58 Dietary calcium deficiency
0.535 0.465 0.000
E54 Ascorbic acid deficiency
0.535 0.465 0.000
E52 Niacin deficiency [pellagra]
0.535 0.465 0.000
E22.1 Hyperprolactinaemia
0.533 0.467 0.000
E51 Thiamine deficiency
0.532 0.468 0.000
E14.9 Without complications
0.522 0.478 0.000
E14.8 With unspecified complications
0.519 0.481 0.000
E31.9 Polyglandular dysfunction, unspecified
0.516 0.484 0.000
E31.8 Other polyglandular dysfunction
0.516 0.484 0.000
E31.1 Polyglandular hyperfunction
0.516 0.484 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.513 0.487 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.513 0.487 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.513 0.487 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.513 0.487 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.513 0.487 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.513 0.487 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.513 0.487 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.513 0.487 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.505 0.494 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.496 0.504 0.000
E45 Retarded development following protein-energy malnutrition
0.496 0.504 0.000
E43 Unspecified severe protein-energy malnutrition
0.496 0.504 0.000
E42 Marasmic kwashiorkor
0.496 0.504 0.000
E41 Nutritional marasmus
0.496 0.504 0.000
E40 Kwashiorkor
0.496 0.504 0.000
E23.2 Diabetes insipidus
0.496 0.504 0.000
E14.4 With neurological complications
0.494 0.506 0.000
E27.8 Other specified disorders of adrenal gland
0.492 0.508 0.000
E29 Testicular dysfunction
0.489 0.511 0.000
E21.3 Hyperparathyroidism, unspecified
0.484 0.516 0.000
E23.6 Other disorders of pituitary gland
0.484 0.516 0.000
E12.9 Without complications
0.481 0.518 0.000
E12.8 With unspecified complications
0.481 0.518 0.000
E12.7 With multiple complications
0.481 0.518 0.000
E12.6 With other specified complications
0.481 0.518 0.000
E12.5 With peripheral circulatory complications
0.481 0.518 0.000
E12.4 With neurological complications
0.481 0.518 0.000
E12.3 With ophthalmic complications
0.481 0.518 0.000
E12.2 With renal complications
0.481 0.518 0.000
E12.1 With ketoacidosis
0.481 0.518 0.000
E12.0 With coma
0.481 0.518 0.000
E46 Unspecified protein-energy malnutrition
0.481 0.519 0.000
E25.9 Adrenogenital disorder, unspecified
0.480 0.520 0.000
E25.8 Other adrenogenital disorders
0.480 0.520 0.000
E21.4 Other specified disorders of parathyroid gland
0.466 0.534 0.000
E21.2 Other hyperparathyroidism
0.466 0.534 0.000
E24.8 Other Cushing's syndrome
0.462 0.537 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.462 0.537 0.000
E24.3 Ectopic ACTH syndrome
0.462 0.537 0.000
E24.1 Nelson's syndrome
0.462 0.537 0.000
E30.9 Disorder of puberty, unspecified
0.462 0.538 0.000
E30.8 Other disorders of puberty
0.462 0.538 0.000
E30.1 Precocious puberty
0.462 0.538 0.000
E30.0 Delayed puberty
0.462 0.538 0.000
E32.9 Disease of thymus, unspecified
0.462 0.538 0.000
E32.8 Other diseases of thymus
0.462 0.538 0.000
E32.1 Abscess of thymus
0.462 0.538 0.000
E32.0 Persistent hyperplasia of thymus
0.462 0.538 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.462 0.538 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.462 0.538 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.462 0.538 0.000
E55.0 Rickets, active
0.454 0.545 0.000
E20.8 Other hypoparathyroidism
0.454 0.546 0.000
E20.1 Pseudohypoparathyroidism
0.454 0.546 0.000
E20.0 Idiopathic hypoparathyroidism
0.454 0.546 0.000
E20.9 Hypoparathyroidism, unspecified
0.443 0.557 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.441 0.559 0.000
E23.1 Drug-induced hypopituitarism
0.441 0.559 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.436 0.564 0.000
E22.8 Other hyperfunction of pituitary gland
0.436 0.564 0.000
E34.8 Other specified endocrine disorders
0.435 0.565 0.000
E07.1 Dyshormogenetic goitre
0.434 0.566 0.000
E07.0 Hypersecretion of calcitonin
0.434 0.566 0.000
E07.8 Other specified disorders of thyroid
0.434 0.566 0.000
E24.0 Pituitary-dependent Cushing's disease
0.429 0.570 0.000
E34.5 Androgen resistance syndrome
0.424 0.576 0.000
E34.4 Constitutional tall stature
0.424 0.576 0.000
E34.3 Short stature, not elsewhere classified
0.424 0.576 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.424 0.576 0.000
E34.1 Other hypersecretion of intestinal hormones
0.424 0.576 0.000
E34.9 Endocrine disorder, unspecified
0.419 0.580 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.407 0.593 0.000
E23.7 Disorder of pituitary gland, unspecified
0.406 0.594 0.000
E06.5 Other chronic thyroiditis
0.405 0.595 0.000
E06.4 Drug-induced thyroiditis
0.405 0.595 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.405 0.595 0.000
E06.1 Subacute thyroiditis
0.405 0.595 0.000
E06.0 Acute thyroiditis
0.405 0.595 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.403 0.597 0.000
E61.1 Iron deficiency
0.401 0.599 0.000
E53 Deficiency of other B group vitamins
0.400 0.600 0.000
E28.3 Primary ovarian failure
0.399 0.601 0.000
E10.4 With neurological complications
0.395 0.604 0.000
E61.2 Magnesium deficiency
0.395 0.605 0.000
E56.1 Deficiency of vitamin K
0.393 0.607 0.000
E61.9 Deficiency of nutrient element, unspecified
0.392 0.608 0.000
E61.8 Deficiency of other specified nutrient elements
0.392 0.608 0.000
E61.7 Deficiency of multiple nutrient elements
0.392 0.608 0.000
E61.6 Vanadium deficiency
0.392 0.608 0.000
E61.5 Molybdenum deficiency
0.392 0.608 0.000
E61.4 Chromium deficiency
0.392 0.608 0.000
E61.3 Manganese deficiency
0.392 0.608 0.000
E61.0 Copper deficiency
0.392 0.608 0.000
E26.9 Hyperaldosteronism, unspecified
0.391 0.609 0.000
E26.8 Other hyperaldosteronism
0.391 0.609 0.000
E26.1 Secondary hyperaldosteronism
0.391 0.609 0.000
E56.9 Vitamin deficiency, unspecified
0.387 0.612 0.000
E56.8 Deficiency of other vitamins
0.387 0.612 0.000
E56.0 Deficiency of vitamin E
0.387 0.612 0.000
E28.9 Ovarian dysfunction, unspecified
0.384 0.616 0.000
E28.8 Other ovarian dysfunction
0.384 0.616 0.000
E28.1 Androgen excess
0.384 0.616 0.000
E28.0 Oestrogen excess
0.384 0.616 0.000
E50.9 Vitamin A deficiency, unspecified
0.383 0.616 0.000
E50.8 Other manifestations of vitamin A deficiency
0.383 0.616 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.383 0.616 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.383 0.616 0.000
E50.5 Vitamin A deficiency with night blindness
0.383 0.616 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.383 0.616 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.383 0.616 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.383 0.616 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.383 0.616 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.383 0.616 0.000
E63.9 Nutritional deficiency, unspecified
0.383 0.616 0.000
E63.8 Other specified nutritional deficiencies
0.383 0.616 0.000
E63.1 Imbalance of constituents of food intake
0.383 0.616 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.383 0.616 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.383 0.616 0.000
E64.8 Sequelae of other nutritional deficiencies
0.383 0.616 0.000
E64.3 Sequelae of rickets
0.383 0.616 0.000
E64.2 Sequelae of vitamin C deficiency
0.383 0.616 0.000
E64.1 Sequelae of vitamin A deficiency
0.383 0.616 0.000
E64.0 Sequelae of protein-energy malnutrition
0.383 0.616 0.000
E51.9 Thiamine deficiency, unspecified
0.381 0.619 0.000
E51.8 Other manifestations of thiamine deficiency
0.381 0.619 0.000
E51.1 Beriberi
0.381 0.619 0.000
E51.2 Wernicke's encephalopathy
0.378 0.622 0.000
E34.0 Carcinoid syndrome
0.362 0.637 0.000
E06.9 Thyroiditis, unspecified
0.362 0.638 0.000
E44.1 Mild protein-energy malnutrition
0.355 0.644 0.000
E44.0 Moderate protein-energy malnutrition
0.355 0.644 0.000
E29.9 Testicular dysfunction, unspecified
0.350 0.649 0.000
E29.8 Other testicular dysfunction
0.350 0.649 0.000
E29.0 Testicular hyperfunction
0.350 0.649 0.000
E22.0 Acromegaly and pituitary gigantism
0.338 0.661 0.000
E65-E68 Obesity and other hyperalimentation
0.332 0.668 0.000
E07.9 Disorder of thyroid, unspecified
0.325 0.675 0.000
E06.3 Autoimmune thyroiditis
0.321 0.679 0.000
E24.9 Cushing's syndrome, unspecified
0.314 0.685 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.305 0.695 0.000
E26.0 Primary hyperaldosteronism
0.291 0.708 0.000
E53.9 Vitamin B deficiency, unspecified
0.288 0.712 0.000
E53.1 Pyridoxine deficiency
0.287 0.713 0.000
E53.0 Riboflavin deficiency
0.287 0.713 0.000
E23.0 Hypopituitarism
0.285 0.715 0.000
E28.2 Polycystic ovarian syndrome
0.246 0.754 0.000
N40-N51 Diseases of male genital organs
0.000 0.760 0.240
E67 Other hyperalimentation
0.238 0.762 0.000
E68 Sequelae of hyperalimentation
0.238 0.762 0.000
N41 Inflammatory diseases of prostate
0.000 0.775 0.225
N42 Other disorders of prostate
0.000 0.781 0.219
N41.1 Chronic prostatitis
0.000 0.785 0.215
N42.1 Congestion and haemorrhage of prostate
0.000 0.788 0.212
N41.0 Acute prostatitis
0.000 0.797 0.203
E29.1 Testicular hypofunction
0.195 0.805 0.001
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.815 0.185
N42.0 Calculus of prostate
0.000 0.819 0.181
E65 Localised adiposity
0.180 0.820 0.000
N46 Male infertility
0.000 0.820 0.180
N44 Torsion of testis
0.000 0.822 0.178
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.828 0.172
E67.8 Other specified hyperalimentation
0.171 0.829 0.000
E67.3 Hypervitaminosis D
0.171 0.829 0.000
E67.2 Megavitamin-B6 syndrome
0.171 0.829 0.000
E67.1 Hypercarotenaemia
0.171 0.829 0.000
E67.0 Hypervitaminosis A
0.171 0.829 0.000
E04 Other non-toxic goitre
0.165 0.835 0.000
N41.3 Prostatocystitis
0.000 0.839 0.161
N41.2 Abscess of prostate
0.000 0.839 0.161
E83 Disorders of mineral metabolism
0.028 0.839 0.133
N43 Hydrocele and spermatocele
0.000 0.840 0.160
N42.3 Dysplasia of prostate
0.000 0.843 0.157
N45 Orchitis and epididymitis
0.000 0.844 0.156
N42.8 Other specified disorders of prostate
0.000 0.850 0.150
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.851 0.149
E53.8 Deficiency of other specified B group vitamins
0.148 0.852 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.867 0.133
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.867 0.133
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.867 0.133
N41.8 Other inflammatory diseases of prostate
0.000 0.868 0.132
N42.2 Atrophy of prostate
0.000 0.871 0.129
N49.2 Inflammatory disorders of scrotum
0.000 0.873 0.127
N43.4 Spermatocele
0.000 0.877 0.123
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.877 0.123
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.877 0.123
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.877 0.123
N51.2 Balanitis in diseases classified elsewhere
0.000 0.877 0.122
E83.3 Disorders of phosphorus metabolism
0.009 0.880 0.111
E04.8 Other specified non-toxic goitre
0.119 0.881 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.882 0.118
E83.9 Disorder of mineral metabolism, unspecified
0.020 0.885 0.095
E83.8 Other disorders of mineral metabolism
0.020 0.885 0.095
E83.2 Disorders of zinc metabolism
0.020 0.885 0.095
E83.0 Disorders of copper metabolism
0.020 0.885 0.095
N43.2 Other hydrocele
0.000 0.885 0.115
N43.1 Infected hydrocele
0.000 0.885 0.115
N43.0 Encysted hydrocele
0.000 0.885 0.115
R30-R39 Symptoms and signs involving the urinary system
0.000 0.898 0.102
R32 Unspecified urinary incontinence
0.000 0.903 0.097
N42.9 Disorder of prostate, unspecified
0.000 0.905 0.095
E04.0 Non-toxic diffuse goitre
0.093 0.907 0.000
E04.9 Non-toxic goitre, unspecified
0.089 0.911 0.000
N43.3 Hydrocele, unspecified
0.000 0.911 0.089
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.916 0.084
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.917 0.083
R33 Retention of urine
0.000 0.926 0.074
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.930 0.070
R34 Anuria and oliguria
0.000 0.930 0.070
R36 Urethral discharge
0.000 0.932 0.068
E04.1 Non-toxic single thyroid nodule
0.068 0.932 0.000
K90-K93 Other diseases of the digestive system
0.063 0.937 0.000
E83.4 Disorders of magnesium metabolism
0.016 0.940 0.044
N50 Other disorders of male genital organs
0.000 0.943 0.057
E04.2 Non-toxic multinodular goitre
0.050 0.950 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.951 0.049
H53.1 Subjective visual disturbances
0.048 0.952 0.000
E70-E90 Metabolic disorders
0.043 0.952 0.005
M20.5 Other deformities of toe(s) (acquired)
0.000 0.954 0.046
N50.9 Disorder of male genital organs, unspecified
0.000 0.954 0.046
K93 Disorders of other digestive organs in diseases classified elsewhere
0.045 0.954 0.000
E11 Non-insulin-dependent diabetes mellitus
0.042 0.958 0.000
E66 Obesity
0.042 0.958 0.000
T39.1 4-Aminophenol derivatives
0.000 0.958 0.042
E84 Cystic fibrosis
0.035 0.962 0.003
E70 Disorders of aromatic amino-acid metabolism
0.034 0.963 0.003
E11.6 With other specified complications
0.037 0.963 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.034 0.964 0.002
R30 Pain associated with micturition
0.000 0.964 0.036
E77 Disorders of glycoprotein metabolism
0.031 0.965 0.003
E76 Disorders of glycosaminoglycan metabolism
0.031 0.965 0.003
E72 Other disorders of amino-acid metabolism
0.031 0.965 0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.031 0.965 0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.031 0.965 0.003
E11.5 With peripheral circulatory complications
0.034 0.966 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.030 0.967 0.004
K44 Diaphragmatic hernia
0.000 0.967 0.033
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.032 0.967 0.000
K93.1 Megacolon in Chagas' disease
0.032 0.967 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.032 0.967 0.000
K40 Inguinal hernia
0.000 0.967 0.033
E79 Disorders of purine and pyrimidine metabolism
0.029 0.968 0.004
N50.0 Atrophy of testis
0.000 0.968 0.032
E74 Other disorders of carbohydrate metabolism
0.029 0.968 0.003
C44.2 Skin of ear and external auricular canal
0.032 0.968 0.000
E88 Other metabolic disorders
0.029 0.969 0.002
E11.7 With multiple complications
0.030 0.969 0.000
E83.5 Disorders of calcium metabolism
0.026 0.970 0.004
E84.9 Cystic fibrosis, unspecified
0.029 0.970 0.002
E66.1 Drug-induced obesity
0.030 0.970 0.000
E73 Lactose intolerance
0.026 0.970 0.004
E70.3 Albinism
0.028 0.970 0.002
E80.2 Other porphyria
0.028 0.970 0.001
E66.2 Extreme obesity with alveolar hypoventilation
0.029 0.971 0.000
E84.8 Cystic fibrosis with other manifestations
0.025 0.973 0.002
E84.1 Cystic fibrosis with intestinal manifestations
0.025 0.973 0.002
E84.0 Cystic fibrosis with pulmonary manifestations
0.025 0.973 0.002
E80.4 Gilbert's syndrome
0.027 0.973 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.025 0.973 0.002
E70.8 Other disorders of aromatic amino-acid metabolism
0.025 0.973 0.002
E70.2 Disorders of tyrosine metabolism
0.025 0.973 0.002
E70.1 Other hyperphenylalaninaemias
0.025 0.973 0.002
E70.0 Classical phenylketonuria
0.025 0.973 0.002
E80.7 Disorder of bilirubin metabolism, unspecified
0.025 0.974 0.002
E80.5 Crigler-Najjar syndrome
0.025 0.974 0.002
E80.3 Defects of catalase and peroxydase
0.025 0.974 0.002
E80.1 Porphyria cutanea tarda
0.025 0.974 0.002
E80.0 Hereditary erythropoietic porphyria
0.025 0.974 0.002
S92.30 Fracture of metatarsal bone (closed)
0.026 0.974 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.974 0.026
E11.8 With unspecified complications
0.026 0.974 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.025 0.974 0.001
R30.1 Vesical tenesmus
0.000 0.975 0.025
E71.3 Disorders of fatty-acid metabolism
0.022 0.975 0.003
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.022 0.975 0.003
E71.1 Other disorders of branched-chain amino-acid metabolism
0.022 0.975 0.003
E71.0 Maple-syrup-urine disease
0.022 0.975 0.003
E72.9 Disorder of amino-acid metabolism, unspecified
0.022 0.975 0.003
E72.8 Other specified disorders of amino-acid metabolism
0.022 0.975 0.003
E72.5 Disorders of glycine metabolism
0.022 0.975 0.003
E72.4 Disorders of ornithine metabolism
0.022 0.975 0.003
E72.3 Disorders of lysine and hydroxylysine metabolism
0.022 0.975 0.003
E72.2 Disorders of urea cycle metabolism
0.022 0.975 0.003
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.022 0.975 0.003
E72.0 Disorders of amino-acid transport
0.022 0.975 0.003
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.022 0.975 0.003
E76.8 Other disorders of glucosaminoglycan metabolism
0.022 0.975 0.003
E76.3 Mucopolysaccharidosis, unspecified
0.022 0.975 0.003
E76.2 Other mucopolysaccharidoses
0.022 0.975 0.003
E76.1 Mucopolysaccharidosis, type II
0.022 0.975 0.003
E76.0 Mucopolysaccharidosis, type I
0.022 0.975 0.003
E77.9 Disorder of glycoprotein metabolism, unspecified
0.022 0.975 0.003
E77.8 Other disorders of glycoprotein metabolism
0.022 0.975 0.003
E77.1 Defects in glycoprotein degradation
0.022 0.975 0.003
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.022 0.975 0.003
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.975 0.025
E88.9 Metabolic disorder, unspecified
0.023 0.975 0.001
E11.1 With ketoacidosis
0.024 0.976 0.000
N48 Other disorders of penis
0.000 0.976 0.024
E80.6 Other disorders of bilirubin metabolism
0.022 0.976 0.002
E75.6 Lipid storage disorder, unspecified
0.021 0.976 0.003
E75.4 Neuronal ceroid lipofuscinosis
0.021 0.976 0.003
E75.3 Sphingolipidosis, unspecified
0.021 0.976 0.003
E75.2 Other sphingolipidosis
0.021 0.976 0.003
E75.1 Other gangliosidosis
0.021 0.976 0.003
E75.0 GM2 gangliosidosis
0.021 0.976 0.003
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.976 0.024
K44.1 Diaphragmatic hernia with gangrene
0.000 0.976 0.024
E66.0 Obesity due to excess calories
0.024 0.976 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.976 0.024
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.021 0.976 0.003
E79.8 Other disorders of purine and pyrimidine metabolism
0.021 0.976 0.003
E79.1 Lesch-Nyhan syndrome
0.021 0.976 0.003
E74.9 Disorder of carbohydrate metabolism, unspecified
0.021 0.977 0.003
E74.8 Other specified disorders of carbohydrate metabolism
0.021 0.977 0.003
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.021 0.977 0.003
E74.2 Disorders of galactose metabolism
0.021 0.977 0.003
E74.1 Disorders of fructose metabolism
0.021 0.977 0.003
E74.0 Glycogen storage disease
0.021 0.977 0.003
E88.8 Other specified metabolic disorders
0.022 0.977 0.002
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.023 0.977 0.000
H53 Visual disturbances
0.023 0.977 0.000
E11.0 With coma
0.022 0.977 0.000
E75.5 Other lipid storage disorders
0.020 0.977 0.003
E88.3 Tumour lysis syndrome
0.021 0.977 0.002
E88.1 Lipodystrophy, not elsewhere classified
0.021 0.977 0.002
E73.8 Other lactose intolerance
0.019 0.978 0.003
E73.1 Secondary lactase deficiency
0.019 0.978 0.003
E73.0 Congenital lactase deficiency
0.019 0.978 0.003
E78.6 Lipoprotein deficiency
0.022 0.978 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.018 0.979 0.003
E89.2 Postprocedural hypoparathyroidism
0.021 0.979 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.019 0.979 0.003
E85 Amyloidosis
0.015 0.979 0.006
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.979 0.021
H53-H54 Visual disturbances and blindness
0.021 0.979 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.979 0.021
R30.9 Painful micturition, unspecified
0.000 0.979 0.020
K40-K46 Hernia
0.000 0.980 0.020
N50.1 Vascular disorders of male genital organs
0.000 0.980 0.020
S92.3 Fracture of metatarsal bone
0.020 0.980 0.000
E78.4 Other hyperlipidaemia
0.020 0.980 0.000
E88.2 Lipomatosis, not elsewhere classified
0.018 0.980 0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.981 0.019
E78.8 Other disorders of lipoprotein metabolism
0.019 0.981 0.000
H53.5 Colour vision deficiencies
0.019 0.981 0.000
N48.4 Impotence of organic origin
0.000 0.981 0.019
N48.3 Priapism
0.000 0.981 0.019
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.018 0.981 0.001
E89.8 Other postprocedural endocrine and metabolic disorders
0.018 0.981 0.001
E89.5 Postprocedural testicular hypofunction
0.018 0.981 0.001
E89.1 Postprocedural hypoinsulinaemia
0.018 0.981 0.001
H54 Blindness and low vision
0.018 0.982 0.000
E89.3 Postprocedural hypopituitarism
0.017 0.982 0.001
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.017 0.982 0.001
E11.3 With ophthalmic complications
0.018 0.982 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.017 0.982 0.001
E89.4 Postprocedural ovarian failure
0.017 0.982 0.001
Chapter VII Diseases of the eye and adnexa
0.018 0.982 0.000
E78.1 Pure hyperglyceridaemia
0.017 0.982 0.000
N48.5 Ulcer of penis
0.000 0.982 0.017
H26.9 Cataract, unspecified
0.018 0.982 0.000
T39.4 Antirheumatics, not elsewhere classified
0.000 0.982 0.017
T39.2 Pyrazolone derivatives
0.000 0.982 0.017
H46-H48 Disorders of optic nerve and visual pathways
0.017 0.983 0.000
H26 Other cataract
0.017 0.983 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.017 0.983 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.017 0.983 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.983 0.017
H25-H28 Disorders of lens
0.017 0.983 0.000
E78.3 Hyperchylomicronaemia
0.017 0.983 0.000
E73.9 Lactose intolerance, unspecified
0.014 0.983 0.003
H53.4 Visual field defects
0.017 0.983 0.000
N48.0 Leukoplakia of penis
0.000 0.983 0.017
H53.6 Night blindness
0.017 0.983 0.000
H53.3 Other disorders of binocular vision
0.017 0.983 0.000
S93.1 Dislocation of toe(s)
0.017 0.983 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.017 0.983 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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